Vitamin A Compound Or Derivative Patents (Class 514/725)
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Publication number: 20100113352Abstract: A composition for the treatment of skin comprises a non-emulsified, aqueous suspension of retinol. The composition may further include at least one protein species, and some proteins used in the composition include collagen and elastin. The composition may also include hyaluronic acid. The composition may also include one or more of tocopheryl acetate, propylene glycol, and linseed extract. Also disclosed are methods for making the composition and use of the composition for the treatment of skin.Type: ApplicationFiled: October 20, 2009Publication date: May 6, 2010Inventor: Elliott Millstein
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Publication number: 20100113587Abstract: The present invention relates generally to the fields of molecular biology and pharmacology. More particularly, it concerns the use of abscissic acid to treat various diseases, including neurodegenerative diseases and neuromuscular diseases.Type: ApplicationFiled: March 6, 2006Publication date: May 6, 2010Inventors: Robert H. Broyles, Robert A. Floyd, Visar Belegu, Austin C. Roth
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Patent number: 7709536Abstract: The invention relates to pharmaceutical formulations, and more particularly to formulations containing cannabinoids for administration via a pump action spray. In particular, the invention relates to pharmaceutical formulations, for use in administration of lipophilic medicaments via mucosal surfaces, comprising: at least one lipophilic medicament, a solvent and a co-solvent, wherein the total amount of solvent and co-solvent present in the formulation is greater than 55% wt/wt of the formulation and the formulation is absent of a self emulsifying agent and/or a fluorinated propellant.Type: GrantFiled: September 16, 2005Date of Patent: May 4, 2010Assignee: GW Pharma LimitedInventor: Brian Whittle
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Publication number: 20100104644Abstract: Methods are disclosed for treating or preventing ophthalmic conditions related to a toxic visual cycle product. Compounds and compositions useful in these methods, either alone or in combination with other therapeutic agents, are also described, along with methods of screening for new agents useful in said the therapeutic and prophylactic methods of the invention.Type: ApplicationFiled: July 27, 2007Publication date: April 29, 2010Applicant: University of Florida Research Foundation, Inc.Inventors: Shalesh Kaushal, Syed Mohammed Noorwez
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Publication number: 20100092446Abstract: It is an object of the present invention to provide a drug solution which has a reduced dissolved oxygen content and is less susceptible to oxidative degradation and highly stable over time, a production method therefor, and a drug solution containing pack which is capable of maintaining the dissolved oxygen content of a drug solution at a reduced level, less susceptible to oxidative degradation of the drug solution and highly stable over time. To achieve the aforementioned object, the reduced-dissolved-oxygen-content drug solution is produced by filling and sealing the drug solution in a drug solution container (15) formed of a plastic material having an oxygen permeability of not lower than 200 cm3/m2·24 h·atm at 25° C. at 60% RH within 12 hours after a steam sterilization process or a hot water sterilization process and having a steady-state oxygen permeability of not higher than 100 cm3/m2·24 h·atm at 25° C.Type: ApplicationFiled: October 25, 2007Publication date: April 15, 2010Inventors: Nobuaki Sumiyoshi, Isamu Tateishi, Hitoshi Mori, Yasushi Morimoto
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Patent number: 7695732Abstract: The invention pertains to a method of treating or preventing pressure ulcers, comprising enterally administering to a subject in need thereof a composition comprising proteins, carbohydrates, fats, arginine or equivalents thereof, ascorbic acid equivalents and ?-tocopherol equivalents, wherein arginine or equivalents thereof is administered in a daily amount of 3-15 g, ascorbic acid equivalents are administered in a daily amount of 180-840 mg and ?-tocopherol equivalents are administered in a daily amount of 50-400 mg.Type: GrantFiled: November 22, 2004Date of Patent: April 13, 2010Assignee: N.V. NutriciaInventors: Maria Anna Verheul-Koot, Chantal Nelleke Kleijer, Robert Johan Joseph Hageman, Roelof Andre Bork, Maud Goethals
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Publication number: 20100080764Abstract: A basic facial and body treatment cosmetic formulation is a combination of a cationic emulsifying agent, an oil soluble liquid polymer and a naturally occurring lactate buffer system. The basic formulation is a starter system that can be specialized to skin moisturizers, skin lighteners, skin pigmenting agents, sunscreens, antioxidants, line reducing products, wrinkle reducing products, anti-cellulite products, pharmaceuticals and the like.Type: ApplicationFiled: September 28, 2009Publication date: April 1, 2010Inventor: Charles Fox
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Publication number: 20100062040Abstract: A method of forming water soluble microparticles is disclosed that includes the steps of providing a water insoluble food supplement, mixing the food supplement in a water miscible polar solvent, heating the mixture to increase the solubility and dissolve the food supplement into the solvent to form a saturated solution, and streaming the solution into water to form a solvent-water mix such that microparticles of the food supplement are producedType: ApplicationFiled: August 21, 2009Publication date: March 11, 2010Inventors: Donald E. Ackley, Eugene Tu
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Publication number: 20100063162Abstract: A method for predicting preventive and/or therapeutic effect of an RAR-? agonist on a malignant tumor, which comprises the steps of measuring an expression level of a class of p160 family molecule and an expression level of a class of SP110 family molecule in a sample collected from the malignant tumor of a patient, and when the class of the p160 family molecule is dominant in a balance between the expression level of the class of the p160 family molecule and the expression level of the class of the SP110 family molecule, determining that an RAR-? agonist is effective for therapeutic treatment of the malignant tumor of the patient.Type: ApplicationFiled: October 23, 2006Publication date: March 11, 2010Applicant: TAIHO PHARMACEUTICAL CO., LTD.Inventor: Koji MURAKAMI
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Publication number: 20100047198Abstract: A perfume-containing PIT emulsion which is suited to contribute to an excellent and long-lasting scenting of textiles during the use of a dryer. The PIT emulsion is simple for the user to handle and allows the user to better control the user's individual scent experience during the handling of textiles. The PIT emulsions can also be used for aroma therapy purposes and for the scenting of rooms. In addition, a kit made of detergents and the perfume-containing PIT emulsion, which enables the user to obtain optimal laundry scenting results.Type: ApplicationFiled: November 5, 2009Publication date: February 25, 2010Applicant: Henkel AG & Co., KGaAInventors: Gert-Lothar Striepling, Andreas Bauer, Matthias Hloucha, Thomas Gerke, Gerard Veldman
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Publication number: 20100040598Abstract: The present invention relates to a combination of pharmaceutical compositions adapted for oral administration one of which comprises a pharmaceutically active ingredient being acid resistant, and the other of which comprises a pharmaceutically active ingredient being acid labile. Said combination is in the form of a kit of parts which is administered in such way as to use food intake to optimize absorption of both the acid labile and the acid resistant active ingredient. Consequently, the kit of parts of the present invention when administered according to the invention provides improved bioavailability of both the acid-resistant and acid-labile active ingredient.Type: ApplicationFiled: July 10, 2007Publication date: February 18, 2010Inventors: Johannes Raneburger, Franz Xaver Schwarz
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Patent number: 7662855Abstract: Compositions for topical application for treating a skin disorder (e.g., acne) include a retinoid, which is solubilized completely in alcohol only with the aid of cosolvents such as esters (e.g., alkyl benzoate, isopropyl palmitate, isopropyl myristate, diisopropyl adipate and their derivatives). This completely solubilized retinoid can be used to formulate an emulsion system or liquid to powder suspension containing a second active, such as an antibiotic (e.g., clindamycin).Type: GrantFiled: November 9, 2004Date of Patent: February 16, 2010Assignee: Imaginative Research Associates, Inc.Inventors: Mohan Vishnupad, Naomi Vishnupad
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Publication number: 20100028460Abstract: The present invention relates to an improved assay for identifying compounds that may be of use in conjunction with cancer chemotherapeutic agents and anti-proliferative agents, to improve efficacy of such agents and/or render effective compounds with relatively little therapeutic activity. There is also provided a class of compounds of formula (I) and retinoids identified by said assay which may be used in a combination therapy, with current and novel agents, to treat cancers and other diseases associated with abnormal host cell proliferation, such as psoriasis.Type: ApplicationFiled: July 25, 2007Publication date: February 4, 2010Inventors: Roland Wolf, John Hayes, Xiu Jun Wang
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Publication number: 20100028318Abstract: The present invention has its object to provide a safer and highly effective composition capable of relieving or preventing xerostomia. The present invention relates to an agent for relieving or preventing xerostomia comprising an oxidized coenzyme Q and/or a reduced coenzyme Q as active ingredients, a composition containing the agent for relieving or preventing xerostomia in a form of a food product, a health food, a dietary supplement, a supplement, an oral health care product, a medicament, a quasi drug, a pet food, a feed or the like, and a method for treating xerostomia and a method for reducing risks of xerostomia comprising administering the composition.Type: ApplicationFiled: January 31, 2008Publication date: February 4, 2010Applicants: KANEKA CORPORATIONInventors: Ichiro Saito, Kenji Fujii, Kazuya Hamada
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Publication number: 20100015221Abstract: The present invention provides an orally rapid disintegrating tablet preparation that contains a high dose of a fat-soluble active ingredient, that exhibits excellent disintegration characteristics in the oral cavity, and that can be produced by a dry tabletting method. The present invention also provides a method of producing an orally rapid disintegrating tablet preparation. The present invention discloses an orally rapid disintegrating tablet preparation that is obtained by tabletting a uniform mixture prepared by mixing saccharide alcohol, crystalline cellulose, and a lubricant with a granule that has been produced by the adsorption of a fat-soluble active ingredient on a porous material.Type: ApplicationFiled: December 20, 2006Publication date: January 21, 2010Applicant: Eisai R&D Management Co.Ltd.Inventors: Norishige Takami, Shinsuke Nagira, Yasushi Okada, Noriko Okada, Takayuki Ohwaki, Reiko Nishijima
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METHOD FOR PREPARING PARTICLES COMPRISING METAL OXIDE COATING AND PARTICLES WITH METAL OXIDE COATING
Publication number: 20100016443Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.Type: ApplicationFiled: February 3, 2008Publication date: January 21, 2010Applicant: SOL-GEL TECHNOLOGIES LTD.Inventors: Ofer Toledano, Haim Bar-Simantov, Nissim Bilman, Leora Shapiro, Raed Abu-Reziq, Srikanth Sriadibhatla, William T. Sommer -
Patent number: 7642288Abstract: Administration of adapalene in a topical medicament to a patient so as to sustain its biological response in the treatment of acne vulgaris, wherein the administration pattern of the topical medicament comprises topically applying onto the afflicted skin area a therapeutically effective amount of adapalene at least once every two days for at least 6 months.Type: GrantFiled: July 26, 2007Date of Patent: January 5, 2010Assignee: Galderma Research & DevelopmentInventor: Michael Graeber
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Publication number: 20090317343Abstract: Personal care compositions are disclosed containing a silicone elastomer from the reaction of an organohydrogen-siloxane having at least two SiH containing cyclosiloxane rings in its molecule, a compound having at least two aliphatic unsaturated groups in its molecule, and a hydrosilylation catalyst.Type: ApplicationFiled: December 19, 2007Publication date: December 24, 2009Inventors: Shaow Lin, Isabella Van Reeth
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Publication number: 20090311329Abstract: The present invention relates to the field of food technology and delivery of hydrophobic biologically active compounds, particularly nutrients, via food products and beverages. In particular the present invention provides isolated casein micelles useful for the encapsulation of hydrophobic nutrients, therapeutic and cosmetic compounds, compositions thereof and methods of preparing the micelles.Type: ApplicationFiled: April 19, 2007Publication date: December 17, 2009Inventors: Yoav D. Livney, Douglas G. Dalgleish
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Publication number: 20090291919Abstract: Methods are disclosed for treating ophthalmic conditions related to the production of toxic visual cycle products that accumulate in the eye, and are associated with reactions of the visual cycle during medical procedures that expose the eye to light, most commonly the various forms of ophthalmic surgery. Compounds and compositions useful in the these methods, either alone or in combination with other therapeutic agents, are also described, along with methods of screening for new agents useful in said treatments.Type: ApplicationFiled: January 21, 2009Publication date: November 26, 2009Applicant: University of Florida Research Foundation, Inc.Inventors: Shalesh Kaushal, Syed M. Noorwez
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Publication number: 20090263513Abstract: The present invention features novel cosmetic skin care compositions for lightening hyperpigmentation.Type: ApplicationFiled: April 18, 2008Publication date: October 22, 2009Inventor: Jan Marini
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Patent number: 7605185Abstract: A polypeptide is identified as being functionally included in a signal transduction pathway having a biological effect. Contemplated polypeptides are different from a retinoic acid receptor, a retinoid X receptor, or a cellular retinoic acid binding protein, however bind a retinoid or retinoid metabolite, and binding of the retinoid or retinoid metabolite lead to a modulation of the biological effect. In particularly contemplated methods, a retinoid or retinoid metabolite is administered to a cell or mammal in a concentration effective to modulate the biological effect.Type: GrantFiled: February 17, 2005Date of Patent: October 20, 2009Inventor: Gerhart Graupner
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Publication number: 20090214661Abstract: A process for the production of cross-linked beadlets containing one or more active ingredients selected from the group of a fat-soluble vitamin active material, a carotenoid and a polyunsaturated fatty acid is provided. The process comprises treating a dry particulate form at a temperature in the range of from 90° C. to 140° C. for a time period of from 30 seconds to 30 minutes or from 1 minute to 10 minutes or from 3 minutes to 7 minutes.Type: ApplicationFiled: April 1, 2009Publication date: August 27, 2009Applicant: DSM IP ASSETS B.V.Inventors: Sylvain DIGUET, Toresten Huber, Johann Ulm
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Publication number: 20090214504Abstract: A method for treating a patient suffering from a wound, ulcer, or inflammation includes providing a topical formulation comprising a carrier and a combination of active ingredients that includes at least one retinoid and at least one blood vessel dilator, and applying the topical formulation to the skin of the patient to cause healing, accelerated healing or prevention of the wound, ulcer or inflammation. Additional active ingredients may include a promoter of mitochondrial function or an antioxidant.Type: ApplicationFiled: January 22, 2009Publication date: August 27, 2009Applicant: BIOCHEMICS, INC.Inventors: Stephen G. Carter, Zhen Zhu, Kanu Patel, Diane L. Kozwich
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Patent number: 7572462Abstract: The invention provides a nutritional supplement system and program for patients undergoing or who have undergone a surgical or other invasive or stressful procedure, or who have suffered an injury. This nutritional supplement for the peri-operative period is designed to prevent deficiencies of nutrients needed for optimal health and healing during this period or for general application and to enable the person receiving the nutritional supplementation to achieve maximum healing and rapid recovery from a procedure or injury.Type: GrantFiled: March 19, 2007Date of Patent: August 11, 2009Inventor: Edward M. Lane
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Publication number: 20090180974Abstract: The invention relates to an agent or a composition for protecting body cells for the preventive and/or performance-enhancing influencing of body cells. The agent comprises a combination of herbal active substances and vitamins and amino acids, with one active substance consisting of polyphenols from green tea.Type: ApplicationFiled: October 23, 2006Publication date: July 16, 2009Inventor: Hans-Emanuel Holzgang
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Publication number: 20090181076Abstract: Methods of producing a controlled release formulation for an active substance are disclosed, wherein the methods involve dispersing a discontinuous phase comprising an active substance into a continuous phase so as to form a two-phase liquid system comprising droplets of said discontinuous phase, and allowing nanoparticles provided to the two-phase liquid system to congregate at the phase interface to thereby coat the surface of the droplets in at least one layer of said nanoparticles. The methods utilise a concentration of a suitable electrolyte which enhances the nanoparticle congregation such that the coating of nanoparticles on the surface of the droplets presents a semi-permeable barrier to the active substance, or otherwise utilise a amount of the active substance that is greater than the solubility limit of that active substance in the discontinous phase. Formulations comprising vitamin A (retinol) as the active substance for dermal delivery are specifically exemplified.Type: ApplicationFiled: May 4, 2007Publication date: July 16, 2009Applicant: University of South AustraliaInventors: Clive Allan Prestidge, Spomenka Simovic, Nasrin Ghouchi Eskandar
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Patent number: 7560123Abstract: The present invention relates to compositions that may be swallowable, chewable or dissolvable, comprising various vitamins and minerals, and in a specific embodiment comprising vitamin A, beta carotene, B-complex vitamins, vitamin C, vitamin D3, vitamin E, iron, magnesium and zinc, and methods for using these compositions for nutritional supplementation in subjects undergoing physiologically stressful events, such as, for example and without limitation, pregnancy, lactation or any disease state.Type: GrantFiled: August 12, 2004Date of Patent: July 14, 2009Assignee: Everett Laboratories, Inc.Inventors: John A. Giordano, Charles J. Balzer
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Publication number: 20090176876Abstract: Compositions, kits and regimens for treatment of damaged skin, especially décolletage, include application of a retinoid, hydroquinone or hydroquinone derivatives, and a composition containing a multi-metal complex.Type: ApplicationFiled: December 10, 2008Publication date: July 9, 2009Applicant: JR CHEM, LLCInventors: Jose E. Ramirez, Joseph R. Faryniarz
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Publication number: 20090136470Abstract: Methods of stimulating or increasing differentiation to regulatory T cells, cultures of regulatory T cells and methods of reducing or decreasing an immune response, inflammation or an inflammatory response, among other things, are provided. Methods include, among other things, contacting blood cells or T cells with an amount of TGF-beta or a TGF-beta analogue and a retinoic acid receptor agonist, or an amount of a retinoid X receptor (RXR) or peroxisome proliferator activated receptor-gamma (PPARgamma) agonist, sufficient to stimulate or increase differentiation to regulatory T cells. Cultures of regulatory T cells include T cells that express a marker associated with regulatory T cells, such as cultures in which regulatory T cells represent, for example, 30% or more of the total number of cells in the culture.Type: ApplicationFiled: June 13, 2008Publication date: May 28, 2009Inventors: HILDE CHEROUTRE, YUNJI PARK, DANIEL DE SOUSA MUCIDA, IDELFONSO VICENTE-SUAREZ
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Publication number: 20090131537Abstract: Formulations and methods for treating wounds utilizing these formulations are disclosed. The formulations accelerate wound healing by providing a unique serum-free cellular nutrient medium that supports wound healing of mammalian skin in the absence of protein growth factors. The protein-free composition contains physiological levels of a retinoid compound. This retinoid-containing composition enhances epidermal wound healing of both normal acute and chronic wounds by stimulating the growth of the adult epidermal keratinocytes without the need of any protein growth factors. The wound healing active composition may be used in combination with a topical wound gel preparation including both proteinaceous and non-proteinaceous biopolymers and hydrogels.Type: ApplicationFiled: November 13, 2008Publication date: May 21, 2009Inventor: John Jacob Wille, JR.
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Publication number: 20090105331Abstract: The present invention relates to compositions containing fat-soluble active ingredients and/or colorants in a matrix based on improved modified polysaccharides, i.e. modified polysaccharides where parts were separated, and to a process for preparing these compositions as well as to these improved modified polysaccharides themselves and a process for the manufacture thereof. The present invention further relates to the use of the compositions of this invention for the enrichment, fortification and/or for the coloration of food, beverages, animal feed, cosmetics and pharmaceutical compositions and to such food, beverages, animal feed, cosmetics and pharmaceutical compositions themselves.Type: ApplicationFiled: February 6, 2007Publication date: April 23, 2009Inventors: David Schaffner, Christian Schafer, Bernd Schlegel
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Publication number: 20090105687Abstract: Angioplasty and other dilatation devices are provided with scoring elements. The device additionally incorporates a separate drug application membrane which is used to deliver drugs and other active substances to a body lumen, typically a blood vessel. The device functions to release drug into a region of the luminal wall as the scoring structure is radially expanded into the lumen wall.Type: ApplicationFiled: September 26, 2008Publication date: April 23, 2009Applicant: AngioScore, Inc.Inventors: Robert K. Deckman, Brian Placek, Michael A. Munrow, Craig Gerbi
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Publication number: 20090075864Abstract: Combination therapy comprising RXR modulators and glucose reabsorption inhibitors useful for the treatment of diabetes and Syndrome X are disclosed.Type: ApplicationFiled: October 24, 2007Publication date: March 19, 2009Inventors: Jacqueline C. Bussolari, Xiaoli Chen, Bruce R. Conway, Keith T. Demarest, Hamish N.M Ross, Rafael Severino
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Publication number: 20090061048Abstract: A complex coacervate delivery system is provided which encapsulates lipophilic nutrients such as, for example, fish oils high in omega-3 fatty acids. The complex coacervate delivery system protects the lipophilic nutrient from degradation, e.g., oxidation and hydrolysis, and also reduces or eliminates the unpleasant taste and odor of the lipophilic nutrient. The complex coacervate delivery system upon ingestion is operative to substantially release the lipophilic nutrient in the lower gastrointestinal tract in a pH-controlled manner. The complex coacervate delivery system may be included in a food or beverage product having a pH value within the range of about 1.5 to about 5.0.Type: ApplicationFiled: August 28, 2007Publication date: March 5, 2009Applicant: PepsiCo, Inc.Inventors: Daniel S. Kohane, Yoon Yeo, Peter Given, Robert S. Langer
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Publication number: 20090054532Abstract: Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein also provide for the screening of modulators of retinol-RBP-TTR complex formation. Furthermore, the methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-related macular degeneration and/or dystrophies.Type: ApplicationFiled: August 11, 2008Publication date: February 26, 2009Applicant: SIRION THERAPEUTICS, INC.Inventors: Nathan L. Mata, Yun Han, Kenneth Widder, Jay Lichter
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Publication number: 20090035292Abstract: Disclosed herein are methods of treating neuroblastomas and medulloblastomas in a subject comprising administering to the subject a phosphatase ligand in an amount effective to treat the subject. Also disclosed herein are method of treating neuroblastomas and medulloblastomas in a subject comprising administering to the subject a histone deacteylase ligand in an amount effective to treat the subject.Type: ApplicationFiled: August 1, 2008Publication date: February 5, 2009Inventors: John S. Kovach, Zhengping Zhuang
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Publication number: 20090036354Abstract: The invention relates to a carrier for administering biologically active compounds comprising one or more C1-C4 alcohols, polyols and polymers thereof, water and one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof. The carrier may be used in administering biologically active compounds, in particular pharmaceuticals including cosmetic agents.Type: ApplicationFiled: June 16, 2006Publication date: February 5, 2009Inventors: Paul Gavin, Robert Gianello, Esra Ogru
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Publication number: 20090035392Abstract: Methods, apparatus, systems and the like for treating acne vulgaris that improves treatment effectiveness and/or reduces bothersome side effects associated with the ingredients used. The present Methods, apparatus, systems, etc., also provide topical compositions of benzoyl peroxide and/or other anti-acne agents that are useful for treating acne vulgaris and may be used simultaneously or sequentially in a user-adjustable ratio of two or more such compositions, or other compositions as desired such as cleansers or lotions.Type: ApplicationFiled: June 9, 2006Publication date: February 5, 2009Inventor: Randall Wilkinson
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Patent number: 7485320Abstract: A liposome formulation for stably incorporating high content of hydrophobic substance is disclosed. The liposome includes two phospholipids with different phase transition temperatures such as saturated and unsaturated phosphatidyl cholines, hydrophobic substances, cholesterol, cholesterol derivatives, antioxidant and hydrophilic polymer-modified lipids such as MPEG-DSPE.Type: GrantFiled: July 23, 2003Date of Patent: February 3, 2009Assignee: Industrial Technology Research InstituteInventors: Pei Kan, Ae-June Wang, Won-Ko Chen, Chih-Wan Tsao
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Publication number: 20090028904Abstract: A process for producing a small-sized, lipid-based cochleate. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca2+ or Zn2+, forms a cochleate precipitate of a particle size less than one micron. The process may be used to produce cochleates containing biologically relevant molecules.Type: ApplicationFiled: April 23, 2008Publication date: January 29, 2009Applicant: BioDelivery Sciences International, Inc.Inventors: Leila Zarif, Tuo Jin, Ignacio Segarra, Raphael J. Mannino
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Publication number: 20090023628Abstract: The present invention relates to a cosmetic composition comprising: a wetting system that comprises at least glycerin in an amount ranging from 8.0% to 10% by weight, based on the total weight of the composition; an emollient system that comprises at least cetyl lactate and Shea butter; an emulsifying system that comprises at least steareth-2 and steareth-21; an oiliness adsorbing system that comprises at least nylon 12; and a silicone system that comprises at least cyclomethicone and cyclomethicone and dimethicone crosspolymer. This multifunctional cosmetic composition exhibits rapid absorption, properties of differentiated softness, smoothness and intensive and prolonged hydration when applied to the skin. Further, the present invention relates to a process of preparing the referred-to cosmetic composition and to a cosmetic product that comprises said composition.Type: ApplicationFiled: December 28, 2005Publication date: January 22, 2009Inventors: Luciana Villa Nova Silva, Alexandre Roberto Silva, Thiago Braz
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Publication number: 20090022818Abstract: A liquid cleansing composition comprising a cleansing surfactant, an adsorbed skin-care agent, adsorptive polymeric particles having an adsorption capacity of at least 2 g of skin care agent per gm of dry polymeric particles, a polymeric thickening agent having a molecular weight in the range of 500,000-10,000,000 Dalton, a water-soluble polymer having a molecular weight in the range of 200-50,000 Dalton, and a hydrophilic liquid, the said cleansing composition having the following features i) the low molecular weight, water-soluble polymer component functions as a foam-boosting and thixotropy-boosting agent; ii) the ratio of the Brookfield viscosity at 1 rpm of spindle speed to the Brookfield viscosity at 100 rpm of spindle speed is at least 10; and iii) the foam-volume is at least 20% higher with the water-soluble, polymeric, foam-boosting component than without it.Type: ApplicationFiled: July 14, 2008Publication date: January 22, 2009Applicant: AMCOL International CorporationInventors: Ashoke K. SenGupta, Limin Liu, Gholam-Reza Vakili-Tahami, Ralph Spindler
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Publication number: 20090017123Abstract: An object of the present invention is to provide a novel dermal regeneration enhancer. In accordance with the present invention, there is provided a dermal regeneration enhancer as a novel pharmaceutical use of lyotropic liquid crystal which has been utilized as a basic material for pharmaceutical preparations for external application and for cosmetics, and the dermal regeneration enhancer of the present invention achieves an excellent suppressive effect to aging of the skin, generation of spots, etc.Type: ApplicationFiled: April 28, 2006Publication date: January 15, 2009Applicants: JAPAN SCIENCE AND TECHNOLOGY AGENCY, NANOEGG RESEARCH LABORATORIES, INC.Inventors: Yoko Yamaguchi, Rie Igarashi
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Patent number: 7476380Abstract: The invention describes a means for the treatment of diseases of the tracheo-bronchial tract, particularly of COPD.Type: GrantFiled: May 12, 2005Date of Patent: January 13, 2009Assignee: GSE-Forschungszentrum fur Umwelt und Gesundheit GmbHInventors: Marion Frankenberger, Konrad Maier, Gerhard Scheuch, Hans-Werner Ziegler-Heitbrock
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Publication number: 20090010968Abstract: The invention relates to a novel formulation of use in cosmetology and in dermatology which uses the storage capacity of the sebaceous glands. The formulation is of the spot-on type and comprises a lipophilic active principle chosen from vitamin A, vitamin E a lipophilic agent for combating free radicals, ceramides or sphingoid bases and steroid hormones, in combination with one or more unsaturated C4-C26 fatty acids and a liquid vehicle, having sebaceous tropism. Application to the localized topical administration of lipophilic active principles.Type: ApplicationFiled: May 12, 2005Publication date: January 8, 2009Inventors: Jean-Claude Allart, Jean-Marie Lefevre, Jacques Peyrot, Jean-Paul Marty
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Publication number: 20090004304Abstract: The present invention provides a powder superior in water-dispersibility/solubility, workability and tabletability, which contains an oil component containing a bioactive substance, a water-soluble polymer, a saccharide other than polysaccharides and a surfactant, at a particular ratio. The powder can be utilized for food, food with nutrient function claims, food for specified health uses, nutritional supplement, nutritional product, animal drug, drinks, feed, pharmaceutical product, quasi-drug, cosmetic and the like.Type: ApplicationFiled: June 23, 2008Publication date: January 1, 2009Applicant: Kaneka CorporationInventors: Toshinori Ikehara, Takayuki Sakogawa
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Publication number: 20080317835Abstract: Assays are preformed to determine nutrient deficiency levels in an individual to address the deficiencies and improve health and longevity. Nutraceutical and cosmeceutical products containing nanoencapsulated active ingredients are provided, in addition to dietary, exercise, sleep, and other lifestyle recommendations.Type: ApplicationFiled: June 20, 2007Publication date: December 25, 2008Inventors: Nazli Azimi, Mohammad Saeed Kharazmi
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Publication number: 20080305193Abstract: A cosmetic composition suitable for topical application to human or animal skin comprising an effective amount of active ingredient dispersed in an acceptable cosmetic base or carrier, wherein the active ingredient comprises a mixture of an amino acid, a low glycemic glycoside and a Vitamin, wherein the amino acid is L-arginine, and wherein the low glycemic glycoside is derived from kiwi fruit.Type: ApplicationFiled: June 5, 2007Publication date: December 11, 2008Inventor: James R. Duprey, JR.
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Publication number: 20080305186Abstract: The present invention includes compositions and methods treat a patient suffering from one or more symptoms of cardiac hypertrophy, hypertension and/or ischemia by administering a pharmaceutically effective amount of a pharmaceutical composition having an anti-epileptic drug and an antibiotic to the patient, for example, the anti-epileptic drug may be carbamazepine and the antibiotic may be doxycycline.Type: ApplicationFiled: June 11, 2007Publication date: December 11, 2008Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Harold R. Garner, Mounir Errami