Alicyclic Ring Containing Patents (Class 514/729)
  • Patent number: 11358985
    Abstract: Provided are a tripeptide compound, a preparation method therefor, and an application thereof. The structure of the related compound is represented by formula (I). The provided compound has angiotensin converting enzyme inhibiting bioactivity, and the compound and a pharmaceutical composition thereof play a role in preventing and treating hypertension and other cardiocerebral vascular system diseases.
    Type: Grant
    Filed: November 27, 2015
    Date of Patent: June 14, 2022
    Assignee: NORTHWEST UNIVERSITY
    Inventors: Xiaohui Zheng, Yajun Bai, Fanggang Qin, Pei Liu, Jiacheng Fang, Xirui He, Xiaoxiao Wang
  • Patent number: 11358921
    Abstract: The invention relates to fused cyclooctyne compounds, and to a method for their preparation. The invention also relates to a conjugate wherein a fused cyclooctyne compound according to the invention is conjugated to a label, and to the use of these conjugates in bioorthogonal labeling, imaging and/or modification, such as for example surface modification, of a target molecule. The invention further relates to a method for the modification of a target molecule, wherein a conjugate according to the invention is reacted with a compound comprising a 1,3-dipole or a 1,3-(hetero)diene.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: June 14, 2022
    Assignee: SYNAFFIX B.V.
    Inventors: Floris Louis Van Delft, Floris Petrus Johannes Theodorus Rutjes, Frederik Jan Dommerholt
  • Patent number: 11279857
    Abstract: A thin adhesive tape includes a base and an adhesive layer provided on one surface of the base, wherein the base has a thickness of 2 to 25 ?m, the adhesive layer has a thickness of 0.1 to 10 ?m, the adhesive tape has a thickness of 30 ?m or less, the adhesive tape has a peel adhesion of 0.50 N/10 mm or more in accordance with JIS Z 0237:2000, and the adhesive tape has a strength to repel members calculated by the following formula of 70 MPa·mm or less, the adhesive tape being excellent in a balance between fixability of members and followability to members: Strength to repel members (MPa·mm)=tensile elastic modulus (MPa) of adhesive tape×thickness (mm) of adhesive tape.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: March 22, 2022
    Assignee: TERAOKA SEISAKUSHO CO., LTD.
    Inventor: Takashi Edahiro
  • Patent number: 11253579
    Abstract: Several embodiments provided in the present disclosure relate to compositions that carry an antigen to which tolerance is desired, the antigen being coupled, bound, or otherwise joined to a targeting moiety, the targeting moiety configured to direct the composition to the liver of a subject. In several embodiments, the antigen in coupled to the targeting moiety by way of a polymeric linker. In several embodiments, the polymeric linker is configured to liberate the antigen in vivo. Methods of using the compositions to reduce and/or prevent unwanted immune responses against an antigen of interest are also provided.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: February 22, 2022
    Assignees: The University of Chicago, Anokion SA
    Inventors: Jeffrey A. Hubbell, David Scott Wilson, Kristen Marie Lorentz, Stephan Kontos
  • Patent number: 11213029
    Abstract: The present invention relates to a composition for controlling plant diseases containing a limonene derivative as an active ingredient. In the present invention, the limonene derivatives have an effect of inhibiting the growth of Xanthomonas oryzae pv. Oryzae (Xoo), which is a pathogen mediating bacterial leaf blight, and Magnaporthe oryzae, which is a pathogen mediating rice blast, and it was confirmed in an experiment with respect to inhibition using volatility (i.e., in a state not being in direct contact with Xoo or M. oryzae) that the limonene derivatives have a growth inhibitory effect. Accordingly, the limonene derivatives have an inhibitory effect against the growth of Xoo and thus they can be effectively used as a composition for controlling plant diseases.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: January 4, 2022
    Assignee: KOREA ATOMIC ENERGY RESEARCH INSTITUTE
    Inventors: Sungbeom Lee, Gun Woong Lee, Kwangwoo Jung, Byung Yeoup Chung, Seungsik Lee, Jin-Hong Kim, Hyoungwoo Bai, Yong-Dae Park
  • Patent number: 11154517
    Abstract: The present disclosure relates to the use of cannabidiol (CBD) for the treatment of atonic seizures. In particular the CBD appears particularly effective in reducing atonic seizures in patients suffering with etiologies that include: Lennox-Gastaut Syndrome; Tuberous Sclerosis Complex; Dravet Syndrome; Doose Syndrome; Aicardi syndrome; CDKL5 and Dup15q in comparison to other seizure types. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).
    Type: Grant
    Filed: April 27, 2021
    Date of Patent: October 26, 2021
    Assignee: GW Research Limited
    Inventors: Geoffrey Guy, Stephen Wright, Orrin Devinsky
  • Patent number: 11096905
    Abstract: The present disclosure relates to the use of cannabidiol (CBD) for the treatment of atonic seizures. In particular the CBD appears particularly effective in reducing atonic seizures in patients suffering with etiologies that include: Lennox-Gastaut Syndrome; Tuberous Sclerosis Complex; Dravet Syndrome; Doose Syndrome; Aicardi syndrome; CDKL5 and Dup15q in comparison to other seizure types. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: August 24, 2021
    Assignee: GW Research Limited
    Inventors: Geoffrey Guy, Stephen Wright, Orrin Devinsky
  • Patent number: 11098003
    Abstract: Control or repellency of bed bugs is accomplished by bringing the bed bugs into contact with at least one of the compounds of the structure (I) Wherein R is selected from —OH, —OC(O)R4, —OR6, —(OR6)2, wherein each R6 is independently selected from an alkyl group containing from 1 to 4 carbon atoms and R4 is a branched or straight chain saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; X is O or CH2, with the proviso that when X is O, R can only be ?O; each Z is independently selected from (CH) and (CH2) y is a numeral selected from 1 and 2; R1 is selected from H or a branched or straight chain saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms. R2 is selected from H and a branched or straight chain saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: August 24, 2021
    Assignee: Bedoukian Research, Inc.
    Inventor: Robert H. Bedoukian
  • Patent number: 10980719
    Abstract: This invention relates to a dentifrice comprising (i) at least one source of ionic tin; and (ii) an antibacterial system comprising caprylyl glycol together with 3-phenyl-1-propanol, phenethyl salicylate, or both 3-phenyl-1-propanol and phenethyl salicylate, as well as to methods of using and of making these compositions.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: April 20, 2021
    Assignee: Colgate-Palmolive Company
    Inventors: Ruth Hinrichs, Andre Brunella, Turan Matur
  • Patent number: 10966939
    Abstract: The present disclosure relates to the use of cannabidiol (CBD) for the treatment of atonic seizures. In particular the CBD appears particularly effective in reducing atonic seizures in patients suffering with etiologies that include: Lennox-Gastaut Syndrome; Tuberous Sclerosis Complex; Dravet Syndrome; Doose Syndrome; Aicardi syndrome; CDKL5 and Dup15q in comparison to other seizure types. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: April 6, 2021
    Assignee: GW Research Limited
    Inventors: Geoffrey Guy, Stephen Wright, Orrin Devinsky
  • Patent number: 10932472
    Abstract: The invention relates to an extract from coffee pulp, a process for its preparation and its use in agrochemical against plant pathogens, especially against fungal infections. The invention also relates to the use of the main active ingredient contained in the extract in agrochemical, optionally in combination with other fungicide agents and/or agents that act as defence elicitors.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: March 2, 2021
    Assignee: KAMAD KNOWLEDGE SOLUTIONS SL
    Inventors: Juan Fernando Gil Romero, Luis Fernando Echeverri López, Francesc Xavier Justribó´Abós
  • Patent number: 10864189
    Abstract: The present invention relates to compositions and methods for the prevention and treatment of skin disorders. In particular, the application describes topical compositions and methods of treatments comprising the combined use of one or more cannabinoids, or use of an ingredient that works on the endocannabinoid system, such as but not limited to, Palmitoylethanolamide (PEA), polyolprepolymers and stem cell extract.
    Type: Grant
    Filed: June 27, 2019
    Date of Patent: December 15, 2020
    Inventor: Jenna Borok
  • Patent number: 10632090
    Abstract: Methods of suppressing cyclooxygenase activity or reducing platelet aggregation of a mammal in need thereof by administering to a mammal in need thereof an effective amount of trans-resveratrol and arginine for a period of at least two weeks.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: April 28, 2020
    Inventors: Shil Kothari, Gary Troxel
  • Patent number: 10517935
    Abstract: A method of treating a synucleinopathy with a peptide (C)DQPVLPD (SEQ ID NO: 59), (C)DMPVLPD (SEQ ID NO: 60), (C)DSPVLPD (SEQ ID NO: 61), (C)DQPVLPDN (SEQ ID NO: 64), (C)DMPVLPDN (SEQ ID NO: 65), (C)DSPVLPDN (SEQ ID NO: 66), (C)HDRPVTPD (SEQ ID NO: 70), (C)DRPVTPD (SEQ ID NO: 71), (C)DVPVLPD (SEQ ID NO: 72), (C)DTPVYPD (SEQ ID NO: 73), (C)DTPVIPD (SEQ ID NO: 74), (C)HDRPVTPDN (SEQ ID NO: 75), (C)DRPVTPDN (SEQ ID NO: 76), (C)DVPVLPDN (SEQ ID NO: 78), (C)DTPVYPDN (SEQ ID NO: 79), (C)DQPVLPDG (SEQ ID NO: 81), (C)DMPVLPDG (SEQ ID NO: 82), (C)DSPVLPDG (SEQ ID NO: 83), (C)DHPVHPDS (SEQ ID NO: 86), (C)DMPVSPDR (SEQ ID NO: 87), (C)DRPVYPDI (SEQ ID NO: 90), (C)DHPVTPDR (SEQ ID NO: 91), (C)DTPVLPDS (SEQ ID NO: 93), (C)DMPVTPDT (SEQ ID NO: 94), (C)DAPVTPDT (SEQ ID NO: 95), (C)DSPVVPDN (SEQ ID NO: 96), (C)DLPVTPDR (SEQ ID NO: 97), (C)DSPVHPDT (SEQ ID NO: 98), (C)DAPVRPDS (SEQ ID NO: 99), (C)DMPVLPDG (SEQ ID NO: 100), (C)DRPVQPDR (SEQ ID NO: 102), (C)YDRPVQPDR (SEQ ID NO: 103), (C)DMPVDADN (SEQ ID NO: 105), DQPVLPD(C) (SE
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: December 31, 2019
    Assignee: AFFIRIS AG
    Inventors: Markus Mandler, Harald Weninger, Radmila Santic, Edith Kopinits
  • Patent number: 10449177
    Abstract: The invention provides compositions and methods for the treatment of mild cognitive impairment (MCI), and for inhibiting, reducing, delaying and/or preventing the progression of MCI to Alzheimer's disease. The methods entail administering an effective amount of one or more compounds selected from the group consisting of tropisetron, disulfuram, honokiol and nimetazepam. The methods also are useful for prophylactic and therapeutic treatment of amyloidogenic diseases, including Alzheimer's disease.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: October 22, 2019
    Assignee: Buck Institute for Research on Aging
    Inventors: Varghese John, Dale E. Bredesen
  • Patent number: 10406129
    Abstract: Methods of suppressing cyclooxygenase activity or reducing platelet aggregation of a mammal in need thereof by administering to a mammal in need thereof an effective amount of trans-resveratrol and arginine for a period of at least two weeks.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: September 10, 2019
    Inventors: Shil Kothari, Gary Troxel
  • Patent number: 10206963
    Abstract: A novel process for incorporating cannabis extract in an emollient carrier. The carrier is a hydrophobic gel that helps to keep skin soft, smooth and hydrated.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: February 19, 2019
    Inventors: Joan McMahon, Stephanie House
  • Patent number: 10058515
    Abstract: The invention provides methods for preventing, ameliorating and treating the acute and chronic forms of graft-versus-host disease (GVHD) by using Cannabidiol compositions.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: August 28, 2018
    Assignee: MOR RESEARCH APPLICATIONS LTD.
    Inventor: Moshe Yeshurun
  • Patent number: 9968565
    Abstract: A method for protection, treatment and improvement of liver health includes administering a meso-zeaxanthin composition in an effective amount to a subject in need thereof. In particular, methods are described of administering a meso-zexanthin composition to a subject fed with high fat diet (HFD), and studying the effect of meso-zeaxanthin for treatment of fatty liver condition, through evaluation of various parameters such as biochemical indicators, anti-inflammatory markers, and nutritional markers.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: May 15, 2018
    Assignee: OmniActive Health Technologies Limited
    Inventors: Jayant Deshpande, Vijaya Juturu, Abhijit Bhattacharya
  • Patent number: 9956182
    Abstract: The invention provides methods for preventing, ameliorating and treating the acute and chronic forms of graft-versus-host disease (GVHD) by using Cannabidiol compositions.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: May 1, 2018
    Assignee: MOR RESEARCH APPLICATIONS LTD.
    Inventor: Moshe Yeshurun
  • Patent number: 9889100
    Abstract: The invention provides methods for preventing, ameliorating and treating the acute and chronic forms of graft-versus-host disease (GVHD) by using Cannabidiol compositions.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: February 13, 2018
    Assignee: MOR RESEARCH APPLICATIONS LTD.
    Inventor: Moshe Yeshurun
  • Patent number: 9833420
    Abstract: Disclosed are methods of preventing, treating, or diagnosing in a subject a disorder in protein folding or aggregation, or amyloid formation, deposition, accumulation, or persistence consisting of administering to said subject a pharmaceutically effective amount of inositol stereoisomers, enantiomers or derivatives thereof.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: December 5, 2017
    Inventor: JoAnne McLaurin
  • Patent number: 9757440
    Abstract: The present invention provides attenuated Toxoplasma gondii mutants for use as vaccines in the prevention or treatment of cancer.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: September 12, 2017
    Assignee: Trustees of Dartmouth College
    Inventors: David J. Bzik, Barbara A. Fox, Steven N. Fiering, Jose R. Conejo-Garcia, Jason Baird
  • Patent number: 9724399
    Abstract: The present invention relates to the use of at least one compound comprising the amino acid sequence (Formula?1) (SEQ?ID?NO:?57) (X1)nX2X3PVX4X5X6(X7)m, wherein X1 is any amino acid residue, X2 is an amino acid residue selected from the group consisting of aspartic acid (D) and glutamic acid (E), X3 is any amino acid residue, X4 is any amino acid residue, X5 is an amino acid residue selected from the group consisting of proline (P) and alanine (A), X6 is an amino acid residue selected from the group consisting of aspartic acid (D) and glutamic acid (E), X7 is any amino acid residue, n and m, independently, are 0 or an integer of more than 0, and wherein the amino acid sequence according to Formula I is not identical with, or does not comprise the 8-mer polypeptide fragment of alpha-synuclein having the amino acid sequence DMPVDPDN (SEQ ID NO: 1), said compound having a binding capacity to an antibody which is specific for an epitope of alpha-synuclein comprising the amino acid sequen
    Type: Grant
    Filed: February 23, 2009
    Date of Patent: August 8, 2017
    Assignee: AFFIRIS AG
    Inventors: Markus Mandler, Harald Weninger, Radmila Santic, Edith Kopinits
  • Patent number: 9526708
    Abstract: A method of reducing nerve damage associated with prostatectomy in a human subject includes the steps of infiltrating a phenylephrine containing solution into the prostate and/or regions adjacent to the prostate and performing a prostatectomy on the human subject. The methods reduce nerve damage often caused by prostatectomy and thereby increase a subject's odds for recovery of full sexual potency as well as complete continence.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: December 27, 2016
    Inventor: James C. Jensen
  • Patent number: 9422227
    Abstract: Provided are compounds and processes of making compounds of the formula: wherein x=4 to 8, R is H, C1 to C4 alkyl, —C(O)OR1 or —OC(O)R1, y=4 to 8, R? is H, C1 to C4 alkyl, and at least one R? is —C(O)OR1 or —OC(O)R1, wherein R1 is a branched C4 to C14 alkyl, and their use in polymer compositions.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: August 23, 2016
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Jihad Mohammed Dakka, Edmund John Mozeleski, Lisa Saunders Baugh, Stephen Zushma
  • Patent number: 9271492
    Abstract: The present invention relates to an antimicrobial composition and a method for disinfection involving the antimicrobial composition. It particularly relates to an antimicrobial composition for personal cleaning, oral care or hard surface cleaning applications. It was found that compositions comprising thymol, menthadiene alcohols and a carrier provide synergistic antimicrobial action. In a preferred aspect the composition also comprises 1 to 80%-wt of one or more surfactants.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: March 1, 2016
    Assignee: Dow Global Technologies LLC
    Inventors: Robert J. Cornmell, Megan A. Diehl, Stephen Golding, John R. Harp, Ian P. Stott, Katherine M. Thompson, Carol L. Truslow
  • Patent number: 9222940
    Abstract: The invention relates to fused cyclooctyne compounds, and to a method for their preparation. The invention also relates to a conjugate wherein a fused cyclooctyne compound according to the invention is conjugated to a label, and to the use of these conjugates in bioorthogonal labeling, imaging and/or modification, such as for example surface modification, of a target molecule. The invention further relates to a method for the modification of a target molecule, wherein a conjugate according to the invention is reacted with a compound comprising a 1,3-dipole or a 1,3-(hetero)diene.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: December 29, 2015
    Assignee: SynAffix B.V.
    Inventors: Floris Louis Van Delft, Floris Petrus Johannes Theodorus Rutjes, Frederik Jan Dommerholt
  • Patent number: 9220680
    Abstract: The invention provides compositions and methods for the prevention, diagnosis, or treatment of conditions affecting breast tissue. The compositions can include one or more therapeutic agents or diagnostic agents, and an effective carrier. The composition can be specifically adapted for transdermal permeation through the mammary papilla, areola, or a combination thereof, and into underlying breast tissue.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: December 29, 2015
    Assignee: South Dakota State University
    Inventors: Omathanu P Perumal, Kaushalkumar Dave, Chandradhar Dwivedi, Sreevidy Santha
  • Publication number: 20150147288
    Abstract: The invention generally relates to environmental friendly pesticide compounds, formulations, methods of preparation and application and utilities thereof. More particularly, the invention relates to pesticide compounds and formulations that include terpenes or terpenoids having chemical formula of (C5H8)n, and its derivatives and analogs thereof, as active insecticidal ingredients; certain botanical essential oils as synergists, and other select ingredients as additives.
    Type: Application
    Filed: February 2, 2015
    Publication date: May 28, 2015
    Inventor: Tao Zhong
  • Publication number: 20150148430
    Abstract: The present disclosure provides phenolic compounds useful in the treatment of neurological conditions such as convulsions and tremors, having the structure of Formula (I): wherein R2, R4, & R5, are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating neurological conditions.
    Type: Application
    Filed: November 24, 2014
    Publication date: May 28, 2015
    Inventors: Max Baker, Rajesh Kumar Mishra, John J. Talley, Eduardo J. Martinez
  • Publication number: 20150141523
    Abstract: A compound of the absolute stereochemical formula and salts thereof is useful in the prophylaxis or treatment of inflammatory bowel disease or other inflammatory autoimmune diseases with similar aetiology involving T-cell proliferation or or function.
    Type: Application
    Filed: May 23, 2013
    Publication date: May 21, 2015
    Inventors: Neil Frankish, Helen Sheridan
  • Publication number: 20150133540
    Abstract: Control or repellency of mosquitoes is accomplished by bringing the insects into contact with at least one of the compounds of the structure (I) wherein R is selected from —OH, ?O, —OC(O)R4, —OR6, —(OR6)2, wherein each R6 is independently selected from an alkyl group containing from 1 to 4 carbon atoms and R4 is a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; X is O or CH2, with the proviso that when X is O R can only be ?O; each Z is independently selected from (CH) and (CH2); y is a numeral selected from 1 and 2; R1 is selected from H or a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to two double bonds and from 1 to 15 carbon atoms; R2 is selected from H and a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero to three double bonds and from 1 to 15 carbon atoms; R3 is selected from the group consisting of H and a branched or straight chain, satur
    Type: Application
    Filed: April 30, 2013
    Publication date: May 14, 2015
    Inventor: Robert H. Bedoukian
  • Publication number: 20150133565
    Abstract: The present invention relates to a thermo-responsive hydrogel polymer formulated with one or more active agents selected from the group consisting of menthol and menthone, wherein said active agents are effective in invigorating the user and/or effective in relieving fatigue.
    Type: Application
    Filed: June 6, 2013
    Publication date: May 14, 2015
    Inventors: Shaojun Yao, W. Rudolf Seitz
  • Publication number: 20150125402
    Abstract: Compounds are used in compositions as antimicrobial agents against microbes, such as for example, Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, and Aspergillus brasiliensis. Antimicrobial action is obtained by contact of a microorganism with at least one of the compounds of the structure (I); wherein R is a branched or straight chain, saturated or unsaturated hydrocarbyl group with zero or one double bond and a total of from 1 to 11 carbon atoms; R1 is —OH, =0 or —OC(0)CH3 and wherein the compounds of structure (I) contain a total of from 9 to 18 carbon atoms in the compounds.
    Type: Application
    Filed: April 30, 2013
    Publication date: May 7, 2015
    Inventor: Robert H. Bedoukian
  • Publication number: 20150126572
    Abstract: A method for treating a patient having ASD is disclosed. The method includes administering to the patient a plurality of comestible units, e.g., cookies, cumulatively comprising a therapeutically effective amount of inositol. The method may further include administering to the patient a therapeutically effective amount of an alpha-2 adrenergic agonist in an extended release dosage form.
    Type: Application
    Filed: January 14, 2015
    Publication date: May 7, 2015
    Inventor: Richard Louis Price
  • Publication number: 20150125410
    Abstract: A hyaluronic acid production promoter and a melanin synthesis inhibitor include soybean saponin as an active ingredient. The soybean saponin can be a soybean saponin aglycone, such as soyasapogenol A and/or soyasapogenol B. The hyaluronic acid production promoter and melanin synthesis inhibitor can be administered transdermally or orally.
    Type: Application
    Filed: January 9, 2015
    Publication date: May 7, 2015
    Inventors: Shuichi KAMO, Shunsuke SUZUKI, Toshiro SATO
  • Publication number: 20150126614
    Abstract: A hyaluronic acid production promoter and a melanin synthesis inhibitor include soybean saponin as an active ingredient. The soybean saponin can be a soybean saponin aglycone, such as soyasapogenol A and/or soyasapogenol B. The hyaluronic acid production promoter and melanin synthesis inhibitor can be administered transdermally or orally.
    Type: Application
    Filed: January 9, 2015
    Publication date: May 7, 2015
    Inventors: Shuichi KAMO, Shunsuke SUZUKI, Toshiro SATO
  • Publication number: 20150118172
    Abstract: The present invention relates to the use of at least one dicyclohexylmethanol derivative of the formula (I) as antimicrobial active compound or as anti-acne, antidandruff, deodorant or antiperspirant active compound, to preparations comprising these compounds, and to specific dicyclohexylmethanol derivatives and to a process for the preparation thereof.
    Type: Application
    Filed: April 5, 2013
    Publication date: April 30, 2015
    Applicant: MERCK PATENT GMBH
    Inventors: Thomas Rudolph, Tatjana Best
  • Publication number: 20150110901
    Abstract: The present invention relates to a novel use of sesquiterpenoid compounds, the pharmaceutically acceptable salts thereof, or the extracts of Cyperus rotundus comprising same or the fractions thereof in the prevention or treatment of menopausal diseases. The sesquiterpenoid compound according to the present invention, the extracts of Cyperus rotundus comprising the same or fractions thereof exhibit excellent estrogenic activity or anti-allergic activity, and therefore they can be used for the prevention or treatment of menopausal diseases caused by a decline in estrogen level or by allergic diseases.
    Type: Application
    Filed: October 17, 2014
    Publication date: April 23, 2015
    Applicant: RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
    Inventors: Kyu Hyuck CHUNG, Jong Hwan KWAK
  • Publication number: 20150110728
    Abstract: Disclosed is a personal care composition comprising cooling active and copolymer comprising acrylamidopropyltrimonium chloride, wherein the weight ratio of the amount of the cooling active to the amount of the copolymer is in the range from 1:5 to 100:1. The copolymer improves deposition of the cooling active during topical application of the product to skin.
    Type: Application
    Filed: April 26, 2013
    Publication date: April 23, 2015
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Amit Jayaswal, Zhengrong Li, Yingying Pi
  • Publication number: 20150105460
    Abstract: Provided in the present invention are various labdane diterpenoid compounds and derivatives thereof for use in preparation of a pharmaceutical composition for preventing or treating neurodegenerative diseases. Also provided in the present invention is a semen biotae extract comprising one or more labdane diterpenoid compounds and derivatives thereof for use in preparation of a pharmaceutical composition for preventing or treating neurodegenerative diseases.
    Type: Application
    Filed: June 4, 2012
    Publication date: April 16, 2015
    Inventors: Weiwei Su, Yonggang Wang, Fengyin Liang, Ning Wang, Zhong Pei, Haibin Liu
  • Publication number: 20150086421
    Abstract: The present invention relates to a method of disinfecting a surface and to an antibacterial composition. Essential oils, which are used as antibacterial actives, are also known for their strong odour; using high amounts of these gives a strong smell to the product that is not always appreciated by the consumer. It is therefore an object of the invention to provide an antibacterial composition, having good anti-bacterial properties, at very low levels of essential oil actives. The present inventors have achieved this using a synergistic combination of select anti-bacterial actives, specific polymers and select hydrotropes.
    Type: Application
    Filed: November 19, 2012
    Publication date: March 26, 2015
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Sujatha Jayaraman, Shanthi Appavoo, Sameer Keshav Barne, Maya Treesa Saji
  • Patent number: 8980951
    Abstract: Bicyclic sesquiterpene compounds exhibiting antifungal characteristics are formulated into antifungal compositions for use in the treatment of fungal infections in humans, animals, and plants. Particularly, sesquiterpene alcohols derived from drimane have been discovered to possess broad-spectrum antifungal characteristics. Exemplary antifungal sesquiterpene compounds include albicanol and drimenol, which have been shown effective against a number of pathogenic fungi.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: March 17, 2015
    Assignee: Kansas State University Research Foundation
    Inventors: Govindsamy Vediyappan, Duy H. Hua
  • Publication number: 20150064261
    Abstract: A multiparticulate dosage form includes a plurality of individual spheroidal enteric coated particulates having (a) a diameter of 0.1 to 2.5 mm; (b) a solid core containing an effective amount of a combination of an L-menthol source and a terpene-based essential oil; (c) a continuous proteinaceous subcoating over the core; and (d) an enteric coating over the subcoating. The multiparticulate dosage form can be used to treat gastrointestinal disorders.
    Type: Application
    Filed: November 7, 2014
    Publication date: March 5, 2015
    Inventors: Syed M. Shah, Fred Hassan, Daniel Hassan, Sarah Hassan
  • Publication number: 20150057342
    Abstract: Provided are oral pharmaceutical compositions comprising sustained release or a combination of sustained and immediate release formulation of cannabinoids, a process for their preparation and methods of use thereof.
    Type: Application
    Filed: July 31, 2014
    Publication date: February 26, 2015
    Inventors: Zohar KOREN, Eyal BALLAN, Itamar BOROCHOV, Shay Avraham SARID
  • Patent number: 8962695
    Abstract: Provided is a hyaluronic acid production promoter and a melanin synthesis inhibitor. The hyaluronic acid production promoter and the melanin synthesis inhibitor of the present invention each contain soybean saponin as an active ingredient. The soybean saponin is preferably soybean saponin aglycone. The soybean saponin aglycone preferably includes soyasapogenol A and/or soyasapogenol B. The hyaluronic acid production promoter and the melanin synthesis inhibitor of the present invention are each administered transdermally or orally.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: February 24, 2015
    Assignee: J-Oil Mills, Inc.
    Inventors: Shuichi Kamo, Shunsuke Suzuki, Toshiro Sato
  • Publication number: 20150051276
    Abstract: Compounds are used as agents that deter feeding of crops by agricultural pests such as hemiptera, lepidoptera and coleoptera, including, but not limited to, stink bugs, codling moth larvae and granary weevils.
    Type: Application
    Filed: April 30, 2013
    Publication date: February 19, 2015
    Inventor: Robert H. Bedoukian
  • Publication number: 20150037276
    Abstract: The present invention provides a hydrocolloid composition which, based on 100% by weight of the hydrocolloid composition, comprises: 10-90%) by weight of a polyisobutylene tackifier; 5-55% by weight of a hydrophilic absorbing substance; and 0.1-20% by weight of a functional ingredient. The invention further provides an article containing the hydrocolloid composition.
    Type: Application
    Filed: November 8, 2011
    Publication date: February 5, 2015
    Applicant: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Ting Fan, Ying Wei Xie, Jing Huang, Kai Qiu, Grace Ho, Dong Wu, Jie Hu
  • Patent number: 8945597
    Abstract: The invention generally relates to environmental friendly pesticide compounds, formulations, methods of preparation and application and utilities thereof. More particularly, the invention relates to pesticide compounds and formulations that include terpenes or terpenoids having chemical formula of (C5H8)n, and its derivatives and analogs thereof, as active insecticidal ingredients; certain botanical essential oils as synergists, and other select ingredients as additives.
    Type: Grant
    Filed: June 18, 2012
    Date of Patent: February 3, 2015
    Inventor: Tao Zhong