Polyhydroxy Patents (Class 514/738)
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Patent number: 8846646Abstract: The invention relates to an unexpected discovery that propylene glycol is highly effective at killing or inhibiting Propionibacterium acnes in a mammalian skin disorder, as well as to the use of propylene glycol and salicylic acid in a skin-disorder treatment. This invention also relates to compositions containing propylene glycol alone or in combination with salicylic acid for use in killing or inhibiting Propionibacterium acnes.Type: GrantFiled: October 3, 2008Date of Patent: September 30, 2014Assignee: Winlind Skincare, LLCInventor: Win L Chiou
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Patent number: 8841264Abstract: Compositions containing a combination of hydroxytyrosol and resveratrol or liqustilide or (?)-epigallocatechin gallate or honokiol or genistein or Magnolia bark extract or a combination of oleuropein and resveratrol or ligustilide are used to treat inflammatory disorders.Type: GrantFiled: July 12, 2007Date of Patent: September 23, 2014Assignee: DSM IP Assets B.V.Inventors: Daniel Raederstorff, Nathalie Richard, Joseph Schwager, Karin Wertz
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Publication number: 20140274683Abstract: Compositions including (a) a pollinating insect repelling, controlling, or directing compound or composition and (b) a compound or composition capable of protecting seeds, plant parts, or plants against insect and/or nematode infestation are provided. The disclosure also provides for methods of repelling, controlling, or directing a pollinating insect, for example a bee, while protecting seeds, plant parts, and/or plants against insect and/or nematode infestation. Seeds, plants, and plant parts treated with compositions described herein are also provided for by the disclosure.Type: ApplicationFiled: March 5, 2014Publication date: September 18, 2014Applicant: Bayer CropScience LPInventors: Tai-Teh WU, Dick ROGERS, Jian ZHANG, Robert CROFT, Chi Yu Roy CHEN
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Patent number: 8835512Abstract: A method and composition for suppressing replication of the HIV-1 virus strains, modulating the production and liberation of inflammatory mediators; and the prevention and treatment of neurocognitive disorders. The method comprises administering to a subject an effective amount of an a macrocyclic diterpenoid, such as 4R cembranoid.Type: GrantFiled: October 11, 2012Date of Patent: September 16, 2014Inventors: Peter Andrew Ferchmin, Vesna Ana Eterovic, Jose Wigberto Rodriguez, Eddy Oscar Rios-Olivares, Antonio Henrique Baccin Martins
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Patent number: 8829053Abstract: An antimicrobial composition with synergistic biocidal activity is described which comprises at least one antimicrobial polymeric biguanide and at least one antimicrobial vicinal diol, said vicinal diol comprises at least one monoalkyl glycol, monoalkyl glycerol, or monoacyl glycerol, to diminish or eliminate biofilm communities. Such synergistic interaction is effective in wound treatment, particularly for chronic wounds, burns and battlefield-induced wounds, as well as for disinfecting non-biological surfaces. The antimicrobial composition can also be prepared as viscous solutions or as gels. The antimicrobial composition may be added to a substrate and dried, such as to a catheter, or to a foam, or to a fiber wound dressing, or coated as a viscous solution or gel upon such devices, to provide controlled release antimicrobial activity.Type: GrantFiled: December 7, 2011Date of Patent: September 9, 2014Assignee: Rochal Industries LLPInventors: Joseph Salamone, Ann Beal Salamone
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Patent number: 8822549Abstract: An oxygen therapeutic composition, comprising a perfluorocarbon material, a viscosity modifier, a buffer, wherein the buffer stabilizes a pH of the composition at between about 6.5 to about 7.5, and wherein the composition comprises a viscosity of about 2.0 to about 3.5 mPas, and wherein the fluorocarbon has a boiling point of about 4 degrees Celsius to about 60 degrees Celsius.Type: GrantFiled: October 13, 2011Date of Patent: September 2, 2014Inventors: Jennifer L. Johnson, Evan C. Unger
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Publication number: 20140243410Abstract: A method is provided for treating a subject in need of medication as an adjunct to elective surgery, comprising administration of a ketogenic material sufficient to produce a physiologically acceptable ketosis in the patient. Preferably the surgery is selected from the groups consisting of removal or section of tumours, removal of redundant organs such as lymph nodes and appendix, open heart surgery, cosmetic surgery, joint and bone surgery.Type: ApplicationFiled: May 7, 2014Publication date: August 28, 2014Applicant: BTG International LimitedInventors: Keith Frank Martin, David John Heal
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Patent number: 8796339Abstract: The present invention relates to a composition comprising or consisting of: (a) one, two or more compounds selected from the group consisting of benzyl alcohol derivatives of the formula (I) wherein each of the substituents R1, R2, and R3 has a position at the aromatic ring, and wherein the substituents R1, R2, and R3 independently of one another are selected from the group consisting of: H; OH; OCH3; COON; linear or branched, saturated aliphatic hydrocarbon radical having 1 to 8 carbon atoms; linear or branched, unsaturated aliphatic hydrocarbon radical having 2 to 8 carbon atoms; COOR4, wherein R4 is a linear or branched alkyl radical having 1 to 8 carbon atoms; wherein the total number of carbon atoms in substituents R1, R2 and R3 is 1 to 12, and (b) one, two or more compounds selected from the group consisting of: (i) branched or unbranched 1,2-alkanediols having 3 to 14 carbon atoms, (ii) benzoic acid (INCI: Benzoic Acid) and its esters and salts, (iii) 4-hydroxybenzoic acid and its esters (Type: GrantFiled: July 10, 2008Date of Patent: August 5, 2014Assignee: Symrise AGInventors: Gerhard Schmaus, Antje Pfeiffer
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Patent number: 8784855Abstract: Pesticides based on vicinal diols, are available to control arthropod ectoparasites such as Pediculus Humanus, Dermatophagoides pteronyssinus, Musca domestica, the Blattidae, Blatella Germanica, and Periplaneta Americana, by introducing to the locus of an infestation of the pest, a composition containing as active ingredient a vicinal diol.Type: GrantFiled: February 12, 2009Date of Patent: July 22, 2014Assignee: Ectopharma LimitedInventors: John Campbell, Andrew Carver
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Patent number: 8779007Abstract: The invention is a cosmetic or dermatological formulation comprising a) at least one polyol in a concentration of from 0.1 to 20% by weight, based on the total weight of the formulation, and b) at least one diol selected from the group consisting of 2-methyl-1,3-propanediol, pentanediol, and hexanediol, in a concentration of from 0.1 to 25% by weight, based on the total weight of the formulation. The invention also includes formulations further comprising at least one antioxidant, and formulations further comprising at least one UV filter. The invention also includes a method of moisturizing skin comprising applying the formulation to the skin. The invention further includes a method for reducing the tacky sensation, a method for reducing the viscosity, and a method for increasing the stability of a polyol-containing formulation comprising adding a diol selected from the group consisting of 2-methyl-1,3-propanediol, pentanediol, and hexanediol.Type: GrantFiled: August 25, 2006Date of Patent: July 15, 2014Assignee: Beiersdorf AGInventors: Rainer Kröpke, Jens Nielsen, Kathrin Wolter
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Publication number: 20140193532Abstract: This invention relates to novel compositions and methods of use by which the compositions of this invention are applied topically to one or more body parts of at least two individuals who bring said body parts into contact with the other individual and, when said body parts come into contact with each other, permit the formulations to interact and thereby achieve an unexpected sensation to each individual.Type: ApplicationFiled: March 10, 2014Publication date: July 10, 2014Applicant: McNeil-PPC, Inc.Inventors: Nawaz Ahmad, Cheng-Ji Cui, Bryant Ison
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Patent number: 8765157Abstract: The present invention relates to compositions and methods for the treatment of topical skin conditions, comprising of Cocoa butter and or petroleum jelly, jojoba oil, dihydrogen oxide, Stearic acid, Anhydrous Magnesium Sulphate, Zinc Oxide, Glycerin and a suitable amount of a pharmaceutically acceptable carrier, shea butter. U.S. Patent Documents 7,429,386 September, 2008 First 6,596,287 July, 2003 Deckers, et al.Type: GrantFiled: January 25, 2012Date of Patent: July 1, 2014Inventor: Agnes Mwangi Blomberg
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Patent number: 8759315Abstract: A ribose-related compound is added to whole blood or packed red cells which have suboptimal function as measured by decreased levels of 2,3-DPG in order to rejuvenate the red blood cells to normal function as seen by raised levels of 2,3-DPG. Two representative ribose-related compounds are D-ribose and inosine.Type: GrantFiled: January 5, 2007Date of Patent: June 24, 2014Assignee: Viacell, LLCInventors: John A St. Cyr, Daniel G Ericson, Clarence A Johnson
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Patent number: 8754134Abstract: Disclosed are compositions that include treated biodiesel glycerin. The disclosed compositions may be utilized as soil-amendments for controlling pests, weeds and for enhancing growth of plants. The biodiesel glycerin utilized in the disclosed compositions may be treated by one or more steps including neutralization, heating, refluxing, condensing, and distilling.Type: GrantFiled: March 15, 2013Date of Patent: June 17, 2014Assignee: Auburn UniversityInventors: Robert H. Walker, Rodrigo Rodríguez-Kábana
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Publication number: 20140161903Abstract: The invention features topical formulations comprising an osmotically active agent and/or a vasoconstrictor and/or an astringent agent for the treatment and prevention of eyelid swelling, and methods of use thereof.Type: ApplicationFiled: February 12, 2014Publication date: June 12, 2014Applicant: ACIEX THERAPEUTICS, INC.Inventors: Matthew J. Chapin, Mark Barry Abelson, Keith Jeffrey Lane, Akimitsu Makino
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Patent number: 8748414Abstract: The present invention relates to a complex made up of at least one molecule of statin or a derivative thereof, covalently bonded to at least one hydrocarbon radical including at least 18 carbon atoms and containing at least one 2-methyl-buta-2-ene unit, to nanoparticles of such a complex, and to a method for preparing same, said complex and/or said nanoparticles optionally being in the form of a lyophilizate. The present invention also relates to a pharmaceutical composition including at least one complex and/or nanoparticles such as previously defined. The invention finally relates to said complex and/or to said nanoparticles for the treatment and/or prevention of hyperlipemia and hypercholesterolemia.Type: GrantFiled: October 28, 2009Date of Patent: June 10, 2014Inventors: Patrick Couvreur, Didier Desmaele, Fat'ma Zouhiri, Reddy Harivardhan Lakkireddy
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Publication number: 20140142190Abstract: Biodegradable single-phase cohesive hydrogels useful, e.g., for the formulation of viscosupplementation compositions or compositions for filling wrinkles, contain a homogeneous blend of x polymers, which may be identical or different, crosslinked prior to the interpenetration thereof by mixing in the form of a single-phase hydrogel, wherein such crosslinked polymers are insoluble in water and miscible with one another, and x ranges from 2 to 5; in one embodiment, the hydrogels are such that the x polymers have identical or different degrees of crosslinking, at least one of the x polymers having a degree of crosslinking x1 and at least one of the x polymers having a degree of crosslinking x2, with x1 being greater than or equal to x2.Type: ApplicationFiled: January 27, 2014Publication date: May 22, 2014Applicant: Laboratoires VivacyInventors: Estelle Marie Piron, Guy Vitally
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Patent number: 8716355Abstract: Compounds of the hydroxytolan family kill tumor cells, inhibit tumor growth and development, and are thus useful in method for treating a tumor or cancer in subjects in need thereof. These compounds are also active in preventing or treating a variety of skin diseases and conditions. The most preferred hydroxytolan compounds are 4,4?-dihydroxytolan. (KST-201), 4 hydroxy 4? trifluoromethyltolan or 4? hydroxy 4 trifluoromethyltolan (KST-213), 3,4?,5-trihydroxytolan or 3?,4,5?-trihydroxytolan (KST-301) and 3,3?,5,5?-tetrahydroxytolan (KST-401). The compounds and methods of using them alone and in combination with ascorbate and certain cyclic compounds to inhibit the development, growth or metastasis of tumor/cancer or preneoplastic cells, or to prevent or treat skin disorders in a subject are disclosed.Type: GrantFiled: June 20, 2008Date of Patent: May 6, 2014Assignee: Kent State UniversityInventor: Chun-che Tsai
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Publication number: 20140121269Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis, which is the % of glucose production that comes from gluconeogenesis (“GNG”), as opposed to glycogenolysis (“GLY”), the other form of glucose production. Nutritional formulations, materials, cocktails and methods for feeding patients by parenteral and other means are disclosed. The amount, type and rate of such nutritional feeding are typically based upon the above estimating. The invention discloses formulations that contain labels, such as deuterium, for medical diagnostics, such as for estimating BES and fractional gluconeogenesis.Type: ApplicationFiled: May 28, 2013Publication date: May 1, 2014Applicant: Run Them Sweet, LLCInventors: Michael A. Horning, George A. Brooks
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Publication number: 20140121172Abstract: Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis, which is the % of glucose production that comes from gluconeogenesis (“GNG”), as opposed to glycogenolysis (“GLY”), the other form of glucose production. Nutritional formulations, materials, cocktails and methods for feeding patients by parenteral and other means are disclosed. The amount, type and rate of such nutritional feeding are typically based upon the above estimating. The invention discloses formulations that contain labels, such as deuterium, for medical diagnostics, such as for estimating BES and fractional gluconeogenesis.Type: ApplicationFiled: May 28, 2013Publication date: May 1, 2014Applicant: Run Them Sweet, LLCInventors: Michael A. Horning, George A. Brooks
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Publication number: 20140120175Abstract: Disclosed is a composition comprising MZ for use as a dietary supplement or food additive for oral consumption for improving the visual performance of a human subject.Type: ApplicationFiled: December 2, 2013Publication date: May 1, 2014Applicant: HOWARD FOUNDATION HOLDINGS LIMITEDInventors: John Nolan, Stephen Beatty, James Loughman, Alan N. Howard, David Thurnham
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Patent number: 8710103Abstract: A method of preserving a cosmetic product by adding to the cosmetic product a concentrate, which may be in anhydrous form, which includes (a) 1-(2-ethylhexyl) glycerol ether, and (b) one or more aromatic alcohols, (a) and (b) having a weight ratio of (a)/(b) is less than or equal to 0.15.Type: GrantFiled: April 11, 2013Date of Patent: April 29, 2014Assignee: Air Liquide Sante (International)Inventors: Wolfgang Beilfuss, Ralf Gradtke, Wolfgang Siegert, Michael Mohr, Klaus Weber
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Patent number: 8710067Abstract: The present invention provides uses of a salt adduct comprising at least one positively charged moiety being a pyridoxine or a derivative thereof and at least one carboxylated 5- to 7-membered lactam ring, optionally additionally substituted, for the preparation of a medicament for the treatment, alleviation of symptoms of, relieving, improving and preventing a cognitive disease, disorder or condition in a subject. Additionally, the invention provides use of said salt adducts for the preparation of medicaments for the improvement of cognitive functions in a healthy subject.Type: GrantFiled: July 3, 2012Date of Patent: April 29, 2014Assignee: Alcobra Ltd.Inventors: Rina Yamin, Dalia Megiddo, Yaron Ilan
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Patent number: 8710252Abstract: The present invention relates to enantiomeric forms of hepoxilin analogs of Formula I-VIII, pharmaceutical compositions thereof, a method for the separation of said enantiomeric forms of hepoxilin analogs comprising applying said hepoxilin to a chiral phase HPLC column and eluting said hepoxilin with an alkane and alcohol solvent mixture. Said enantiomeric forms of hepoxilin analogs of Formula I-VIII were found to be useful in controlling the biological effects of PPAR mediated transcriptional control for the treatment of diseases such as cancer, thromboxane-mediated diseases and for modulating intracellular calcium concentration.Type: GrantFiled: April 19, 2007Date of Patent: April 29, 2014Inventors: Cecil Pace-Asciak, Alexandra SantAna Sorensen, Jean-Philippe Meyer, Peter Denim
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Publication number: 20140106008Abstract: The invention discloses the use of a treatment composition for preventing, or reducing, the production of contaminants selected from microorganisms and microorganism-produced toxins by contacting the substrate with the composition. The composition comprises a water glycerol mixture and calcium hydroxide in which the percentage by mass of glycerol in the water glycerol mixture is between 5% and 95%, at least some of the calcium hydroxide is dissolved in the water glycerol mixture and the concentration of the dissolved calcium hydroxide in the water glycerol mixture is at least 1.5 times higher than the maximum concentration of dissolved calcium hydroxide which can be obtained in water alone, thereby preventing or reducing the production of the contaminants. The extent of the prevention or reduction is at least 1.5 times more than the corresponding prevention or reduction produced by a treatment composition comprising water and calcium hydroxide only.Type: ApplicationFiled: June 21, 2012Publication date: April 17, 2014Applicant: BIO-ENERGY INGREDIENTS LIMITEDInventor: Abraham Christo Venter
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Publication number: 20140107225Abstract: A method and composition for suppressing replication of the HIV-1 virus strains, modulating the production and liberation of inflammatory mediators; and the prevention and treatment of neurocognitive disorders. The method comprises administering to a subject an effective amount of an a macrocyclic diterpenoid, such as 4R cembranoid.Type: ApplicationFiled: October 11, 2012Publication date: April 17, 2014Inventors: Peter Andrew Ferchmin, Vesna Ana Eterovic, Jose Wigberto Rodriguez, Eddy Oscar Rios-Olivares, Antonio Henrique Baccin Martins
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Patent number: 8697125Abstract: The present invention provides a tablet without causing a tableting trouble, which is superior in the tablet formability, dissolution property of pharmaceutically active ingredient, and the like.Type: GrantFiled: January 30, 2008Date of Patent: April 15, 2014Assignee: Takeda Pharmaceutical Company LimitedInventors: Akihiko Ono, Shigeyuki Marunaka, Makoto Fukuta
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Patent number: 8697103Abstract: An alcoholic foam composition, which can be dispensed as a foam via a pump-foam system contains a) at least 52 to ?99 wt % of an alcohol or mixture of alcohols, b) a surfactant or a surfactant mixture, c) at least one polyalkylene glycol, d) optionally, at least one foam stabilizer, e) optionally, at least one member selected from the group consisting of cosmetic auxiliaries, adjuvants, active ingredients, and mixtures thereof, and f) optionally water. The surface tension of component b) lies in the range of ±15 dyn/cm of the surface tension of component a) or corresponds to the surface tension of component a), and the sum of components a) to f) is 100 wt % relative to the total quantity of the foam composition.Type: GrantFiled: February 6, 2012Date of Patent: April 15, 2014Assignee: Deb IP LimitedInventors: Marcel Veeger, Markus Himming
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Patent number: 8691776Abstract: A process for preparing parenteral iron-saccharidic complexes, and the complexes produced, comprising: (1) providing an aqueous solution or dispersion including (i) Fe(III) and (OH)? ions and (ii) at least one saccharide, to form a reaction mixture, where the molar ratio of (i):(ii) is about 30:1 to about 1:30; and the mixture temperature and pH are at or above the complex assembly point (CAP); and (2) maintaining temperature and pH at or above the CAP for a time sufficient to form an iron-saccharidic complex having a molecular weight of about 25,000 Daltons or more. Control of the temperature and pH efficiently produces a high molecular weight complex. The complex can be separated by precipitation, dialysis and/or column fractionation and, if desired, dried, e.g., lyophilized or spray dried. The process can controllably synthesize complexes of varying molecular weight and/or chemical composition, particularly sodium ferric gluconate and ferric hydroxide-sucrose.Type: GrantFiled: May 16, 2011Date of Patent: April 8, 2014Assignee: Chromaceutical Advanced Technologies,Inc.Inventors: Robert A. Beck, Robert A. Mateer, Jr., John Kowalski
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Patent number: 8685439Abstract: The invention features novel topical ophthalmic formulations comprising an osmotically active agent and a vasoconstrictor. Suitable osmotically active agents for use in the ophthalmic formulations of the invention include, without limitation, sodium chloride, dextrose, glycerine, sucrose, mannitol, and sorbitol; suitable vasoconstritors include, without limitation, naphazoline and oxymetazoline. Also provided are methods of using the ophthalmic formulations of the invention for the treatment and prevention of eyelid swelling by administering the ophthalmic formulations of the invention to the eye surface of a subject in need thereof.Type: GrantFiled: April 26, 2007Date of Patent: April 1, 2014Assignee: Aciex Therapeutics, Inc.Inventors: Matthew Jonathan Chapin, Mark Barry Abelson, Keith Jeffrey Lane, Akimitsu Makino
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Publication number: 20140080919Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.Type: ApplicationFiled: November 20, 2013Publication date: March 20, 2014Applicant: ECOLAB USA INC.Inventors: Joseph R. Wegner, Cheryl A. Littau
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Patent number: 8673330Abstract: Insecticidal compositions suitable for use in preparation of insecticidal granular fertilizer and insecticidal formulations comprising a pyrethroid and a glycol present in a concentration of from 40.0% by weight to 99.0% by weight based upon the total weight of all components in the composition is disclosed.Type: GrantFiled: July 10, 2012Date of Patent: March 18, 2014Assignees: FMC Corporation, The Scotts Company LLCInventors: Edward Kikta, Larry G. Faehl, Kim Watson, David R. Kilanowski, Robert Radabaugh, Coby L. Crane
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Patent number: 8673328Abstract: The present invention relates to compositions and methods for the treatment of topical skin conditions, comprising of cocoa butter, petroleum jelly, jojoba oil, dihydrogen oxide, Stearic acid, Anhydrous Magnesium Sulphate, Zinc Oxide, Glycerin and a suitable amount of a pharmaceutically acceptable shea butter.Type: GrantFiled: April 11, 2010Date of Patent: March 18, 2014Inventor: Agnes Mwangi Blomberg
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Patent number: 8663608Abstract: A hydroxytyrosol polymer formed by either C—C coupling or C—O—C coupling is provided. Preferred polymers are formed by C—C coupling and the dimer has the following structure: Compounds of the invention have been found to have antioxidant properties and their use in antioxidant compositions forms a further aspect of the invention.Type: GrantFiled: September 22, 2010Date of Patent: March 4, 2014Assignee: University of Cape TownInventors: Stephanie Gail Burton, Lester Merlin Davids
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Publication number: 20140057983Abstract: An ophthalmic preparation and method, usable to treat conjunctivochalasis. The ophthalmic preparation comprises an aqueous solution of glycerol. The preparation may also include additional components including high molecular weight polymers for viscosity control and pharmacologically active substances. The method includes administering an ophthalmic preparation including an aqueous solution of glycerol to a patient.Type: ApplicationFiled: November 5, 2013Publication date: February 27, 2014Applicant: RESDEVCO RESEARCH AND DEVELOPMENT CO. LTD.Inventor: Shabtay DIKSTEIN
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Patent number: 8658199Abstract: Systems and methods provide sugar alcohol to heat stressed ruminants to improve performance. During periods of high temperature or humidity, heat stressed ruminants may exhibit decreased dry matter intake, and in response, an effective amount of sugar alcohol such as sorbitol may be provided in the ruminant diet to cause performance to increase, which may include increased milk yield, improved feed efficiency or both compared to heat stressed dairy cattle without sugar alcohol in the diet.Type: GrantFiled: February 1, 2012Date of Patent: February 25, 2014Assignee: Purina Animal Nutrition LLCInventors: Bill L. Miller, Jill A. Davidson, Cindie M. Luhman
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Publication number: 20140051769Abstract: A method of improving the health of a first group of young monogastric mammals, the first group of young monogastric mammals nursing from a first lactating monogastric mammal during a pre-weaning period, the method including feeding the first lactating monogastric mammal an effective amount of an animal feed during the pre-weaning period, and feeding the first lactating monogastric mammal an effective amount of sugar alcohol during the pre-weaning period.Type: ApplicationFiled: August 22, 2013Publication date: February 20, 2014Applicant: PURINA ANIMAL NUTRITION LLCInventors: Brenda de Rodas, Cindie M. Luhman, Bill L. Miller, Paul A. Porter
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Publication number: 20140045773Abstract: Ophthalmic compositions including compatible solute components and/or polyanionic components are useful in treating eyes, for example, to relieve dry eye syndrome, to protect the eyes against hypertonic insult and/or the adverse effects of cationic species on the ocular surfaces of eyes and/or to facilitate recovery from eye surgery.Type: ApplicationFiled: September 11, 2013Publication date: February 13, 2014Applicant: Allergan, Inc.Inventors: Joseph G. Vehige, Peter A. Simmons, Joan-En Chang-Lin
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Patent number: 8647651Abstract: Antimicrobial mixtures comprising or consisting of: one or more branched or unbranched alkanediols having 6-12 carbon atoms, one, two or more compounds chosen from the group consisting of the tropolones of the formula (I) wherein the substituents R1, R2, R3, R4 and R5 independently of one another have the following meaning: H; linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; OH; OR6, wherein R6 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; COOH; COOR7, wherein R7 is a linear or branched, saturated or unsaturated, aliphatic hydrocarbon radical having up to 30 C atoms; NO2; NH2; F, Cl, Br, I; are described.Type: GrantFiled: July 27, 2006Date of Patent: February 11, 2014Assignee: Symrise AGInventors: Gerhard Schmaus, Sabine Lange, Ravikumar Pillai, William Johncock
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Publication number: 20140039066Abstract: Disclosed herein are foamable gritty foam compositions that can suspend particulate mechanical scrubbers with particles sized from about 100 microns to about 800 microns that is capable of being foamed through a non-aerosol, or unpressurized pump dispenser.Type: ApplicationFiled: March 14, 2013Publication date: February 6, 2014Inventors: Louise GRIMADELL, David Michael Ross Creaghan, John D. Hines, Pierre Bruno Grascha
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Publication number: 20140037701Abstract: A stack of folded web substrates is disclosed. Each folded web substrate has a folded surface area of about A/8 produced from a respective unfolded web substrate having an unfolded surface area of A and having a lotion applied to one surface thereof. The stack of folded web substrates has a normalized Mellin gauge value of greater than 0.06.Type: ApplicationFiled: August 6, 2012Publication date: February 6, 2014Inventors: André Mellin, Monica Ho-Kleinwaechter, Joseph L. Cuellar
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Patent number: 8633171Abstract: The invention relates to a gellant system for a polar oil comprising gellant effective amounts of silica, a sugar fatty acid ester and a long chain polymer. The gellant system of the invention is useful in gelling polar oils to produce transparent or translucent gels useful in topical compositions.Type: GrantFiled: November 9, 2010Date of Patent: January 21, 2014Assignee: ELC Management, LLCInventors: Dexin Luo, Tian Xiang Wang, Tatyana R. Tabakman, Shahan Nazar, Steven Hasher, Joseph Gubernick
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Publication number: 20140018333Abstract: The invention relates to compositions containing at least 90% by weight of dimer diol for use in a method for the surgical or therapeutic treatment of the human or animal body, and in particular to the use thereof as a body fluid replacement substance.Type: ApplicationFiled: July 10, 2012Publication date: January 16, 2014Applicant: ACTO E.V.Inventor: Norbert SCHRAGE
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Publication number: 20140018438Abstract: Disclosed is a method of preventing or inhibiting biofilm formation by a population of bacteria comprising the administration of a sterile intravenous normal saline solution containing glycerin and amino acids. In some embodiments, the concentration of glycerin in the normal saline solution is approximately 3%. In some embodiments, the concentration of amino acids in the normal saline solution is approximately 3%. In some embodiments, the intravenous solution is administered for 48 hours at 80 cc/hour. In some embodiments, the solution is infused via intracavernous administration into an infected body cavity.Type: ApplicationFiled: June 6, 2013Publication date: January 16, 2014Inventor: Thomas Bryan
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Patent number: 8629180Abstract: A novel antiseptic agent composition which has a wide antimicrobial spectrum and excellent antiseptic properties is provided. An antiseptic agent composition A contains a glycerin hydroxy fatty acid monoester that is an ester of glycerin and a hydroxy fatty acid having 8 to 18 carbon atoms, and a specific antiseptic agent such as an alkanediol. An antiseptic agent composition B contains the glycerin hydroxy fatty acid monoester and an aromatic antiseptic agent. An antiseptic agent composition C contains the glycerin hydroxy fatty acid monoester and a chelating agent.Type: GrantFiled: January 18, 2010Date of Patent: January 14, 2014Assignee: Taiyo CorporationInventors: Shuji Kanatani, Soota Iwamoto
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Publication number: 20140010901Abstract: Provided is a novel bleomycin hydrolase production promoter. Provided is a bleomycin hydrolase production promoter, natural moisturizing factor production promoter, and dry skin remedy, comprising as an active ingredient thereof one or a plurality of ingredients selected from the group consisting of chestnut rose extract, angelica root extract, cork tree bark extract, lamium album extract, rosemary extract, benzenesulfonyl GABA and erythritol.Type: ApplicationFiled: March 14, 2012Publication date: January 9, 2014Inventors: Toshihiko Hibino, Shoko Yamada, Hidekazu Fukushima
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Publication number: 20140010775Abstract: To provide a solid makeup cosmetic material which has a high moisturizing effect, is superior in stability in a humidified environment and allows the moisturizing effect to be actually sensed upon use. In a solid makeup cosmetic material, 33% by mass or more of an oil component and 3 to 15% by mass of a moisturizing agent are incorporated with respect to the total amount of the cosmetic material.Type: ApplicationFiled: March 19, 2012Publication date: January 9, 2014Applicant: SHISEIDO COMPANY, LTD.Inventors: Yuji Sonoyama, Mariko Chihara
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Publication number: 20130345315Abstract: A water-releasing cosmetic composition in the form of an emulsion and process for preparing the cosmetic composition are provided. The cosmetic composition includes an aqueous phase and an oil phase. The aqueous phase includes a hydrating agent at a concentration, by weight, of about 1% to about 50% and a preservative system at a concentration, by weight, based upon weight of the composition. The oil phase includes dimethicone at concentration, by weight of about 1% to about 40%, and an emulsifying crosslinked siloxane elastomer at a concentration, by weight, of about 3% to about 20%, both based upon weight of the composition. The cosmetic composition converts from an emulsion to a plurality of droplets upon rubbing. The process for preparing the water-releasing cosmetic composition includes regular or cold-processing methods to form the emulsion.Type: ApplicationFiled: June 21, 2012Publication date: December 26, 2013Applicant: L'OREAL S.A.Inventor: Catherine CHIOU
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Publication number: 20130345316Abstract: A water-releasing cosmetic composition in the form of an emulsion and process for preparing the cosmetic composition are provided. The cosmetic composition includes an aqueous phase and an oil phase. The aqueous phase includes a hydrating agent at a concentration, by weight, of about 1% to about 50% and a preservative system at a concentration of about 0.1 to 3%, by weight, based upon weight of the composition. The oil phase includes dimethicone at concentration, by weight of about 1% to about 40%, and an emulsifying crosslinked siloxane elastomer at a concentration, by weight, of about 3% to about 20%, both based upon weight of the composition. The cosmetic composition has a phase ratio of the aqueous phase to the oil phase of about 1.5 to about 12.0. The cosmetic composition converts from an emulsion to a plurality of droplets upon rubbing.Type: ApplicationFiled: April 2, 2013Publication date: December 26, 2013Inventor: Catherine CHIOU
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Publication number: 20130344083Abstract: Provided are methods and compositions for treatment of cancer. In particular, these methods and compositions may include an inhibitor of a deubiquitinating enzyme. In certain aspects, these methods and compositions may include a modulator of glucose metabolism. Also provided are methods of assaying the glucose content of cells and tissues using detection of uH2B.Type: ApplicationFiled: March 14, 2013Publication date: December 26, 2013Inventors: C. Wilson Xu, Yasuyo Urasaki