Siliceous Or Calcareous Material (e.g., Clay, Earth, Etc.) Patents (Class 514/770)
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Patent number: 5897869Abstract: The present application relates to an extruded cosmetic composition, provided in the form of a soft paste, comprising, in a fatty phase, at least one compound having a high melting temperature.The invention also relates to a process for preparing the composition by extrusion.Type: GrantFiled: June 3, 1996Date of Patent: April 27, 1999Assignee: L'OrealInventors: Veronique Roulier, Therese Daubige
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Patent number: 5895663Abstract: Pseudoephedrine hydrochloride extended-release tablets including a sustained release hydroxypropylmethylcellulose matrix and a microcrystalline cellulose disintegrant formed by a dry mixed, direct compression method.Type: GrantFiled: July 31, 1997Date of Patent: April 20, 1999Assignee: L. Perrigo CompanyInventors: Jack T. Irwin, Shirish A. Shah
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Patent number: 5888534Abstract: A composition providing a relatively slow release of water-soluble drugs, such as apomorphine, for delivery via the sublingual or buccal routes.Type: GrantFiled: April 29, 1997Date of Patent: March 30, 1999Assignee: Pentech Pharmaceuticals, Inc.Inventors: Ragab El-Rashidy, Bruce Ronsen, Emad Eldin Hassan
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Patent number: 5885617Abstract: A dry moisture barrier film coating composition for forming a moisture barrier film coating for pharmaceutical tablets and the like comprises polyvinyl alcohol, soya lecithin, and optionally a flow aid, a colorant, and/or a suspending agent. A liquid coating solution or dispersion for forming a moisture barrier film coating for pharmaceutical tablets and the like comprises polyvinyl alcohol, soya lecithin, water, and optionally a flow aid, a colorant, and/or a suspending agent. A method of coating pharmaceutical tablets and the like with a moisture barrier film coating comprises forming a liquid coating solution or dispersion for forming a moisture barrier film coating for pharmaceutical tablets and the like comprising polyvinyl alcohol, soya lecithin, water, and optionally a flow aid, a colorant, and/or a suspending agent, applying the coating solution or dispersion onto the tablets to form a film coating on the tablets, and drying the film coating on the tablets.Type: GrantFiled: June 6, 1995Date of Patent: March 23, 1999Assignee: BPSI Holdings, Inc.Inventor: Martin Philip Jordan
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Patent number: 5882689Abstract: This invention provides a method for controlling soilborne fungal disease in cultivated field plants such as a peanut crop. Field crop soil is treated with a free-flowing granular fungicide composition which can be applied by aerial means with minimal settling on plant foliage. The granular fungicide composition comprises ammonium bicarbonate and a solid surfactant ingredient, and is effective against soilborne fungi such as a Sclerotinia, Rhizoctonia, Pythium, Fusarium, Phytophthora or Verticillium species.Type: GrantFiled: December 23, 1997Date of Patent: March 16, 1999Assignee: Church & Dwight Co., Inc.Inventors: M. Steven Lajoie, Carl E. Henry
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Patent number: 5879706Abstract: A tablet comprising at least 50% w/w valaciclovir and 0.05 to 3% w/w colloidal silicon dioxide in which the valaciclovir is present within granules of the tablets and the silicon dioxide, a lubricant and a microcrystalline cellulose filler are present extragranularly has excellent hardness and friability properties while still maintaining lubrication of the tablet granules.Type: GrantFiled: August 29, 1997Date of Patent: March 9, 1999Assignee: Glaxo Wellcome Inc.Inventors: Barry Howard Carter, Lloyd Gary Tillman
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Patent number: 5851406Abstract: A method to prevent the degradation of water soluble film placed in contact with halogenated hydantoin or chlorinated cyanuric acid and an apparatus for disinfecting water systems. Halogenated 5,5-dialkyl hydantoin or chlorinated cyanuric acid is combined with a stabilizing agent to prevent the halogenated hydantoin or chlorinated cyanuric acid from discoloring or degrading a polymeric film which it may contact. The oxidizing agent includes alkaline hydroxide, alkaline carbonates, alkaline bicarbonates, alkaline phosphates, alkaline silicates, and alkaline borates. Polymeric films for which this is suitable include 2-hydroxy propyl cellulose and poly(vinyl alcohol).Type: GrantFiled: November 22, 1995Date of Patent: December 22, 1998Assignee: Bio-Lab, Inc.Inventors: Ronald L. Jones, P. Kirk Mitchell
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Patent number: 5849333Abstract: A delaminated talc has a plurality of high aspect ratio, smooth surface particles. The aspect ratio of the particles is determined by dividing their extent along an upper surface thereof by their thickness. The upper surface is substantially parallel to the lamellar interface direction and the thickness is measured perpendicularly to the interface direction. The upper, lower and side surfaces of the particles are smooth, lacking acute angularity and staircase effect which give rise to increased coefficient of friction and light scattering. The talc is especially suitable in cosmetic and pharmacologic preparations due to its high degree of transparency, skin adhesiveness, lubricity and spreadability.Type: GrantFiled: April 4, 1995Date of Patent: December 15, 1998Assignee: American Westmin, Inc.Inventors: Mary Ann Nordhauser, James Robert Anderson
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Organic/inorganic gels for delivering controlled quantities of active compounds in aqueous solutions
Patent number: 5846555Abstract: The invention concerns a composite gel comprising an inorganic matrix containing a fibrous inorganic polymer in which an active organic compound is dispersed.The invention also concerns a device comprising the gel and a process for delivering a controlled quantity of active organic compound in an aqueous solution.The invention applies to the prevention of biological growth in aqueous solutions used domestically, agriculturally or industrially, in particular in the solutions used in photographic processing.Type: GrantFiled: September 5, 1996Date of Patent: December 8, 1998Assignee: Eastman Kodak CompanyInventors: Olivier Jean Christian Poncelet, Danielle Marie Henriette Wettling, Jeannine Rigola -
Patent number: 5840320Abstract: A method of increasing the bulk density and improving the water-dispersibility, oil sorption capacity, and body dirt and oil removability by compacting and/or shearing a magnesium rich calcium montmorillonite clay. In an optional embodiment of the present invention, silica gel, sodium silicate, acrylic polymers and copolymers, carboxy methyl cellulose, or other materials capable of providing lubricity to the surface of the clay crystals is added to the clay, prior to shearing, to enhance the compaction and/or shearing process and further increase the bulk density of the clay. The clay is sheared in an extruder, pug mill or California-type pellet mill when the clay includes about 20% to about 45%, preferably about 25% to about 40% by weight water, based on the dry weight of the clay.Type: GrantFiled: October 25, 1995Date of Patent: November 24, 1998Assignee: AMCOL International CorporationInventor: Ira Edgar Odom
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Patent number: 5763364Abstract: The invention relates to thixotropic aqueous suspension concentrates of plant protection agents. The invention furthermore relates to the use of these agents in plant protection and the use of saponites as auxiliaries in the preparation of plant protection agent suspensions by wet grinding of the solid constituents.Type: GrantFiled: September 19, 1995Date of Patent: June 9, 1998Assignee: Hoechst Schering AgrEvo GmbHInventors: Gerhard Frisch, Thomas Maier
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Patent number: 5759575Abstract: An effervescent granulated material for a pharmaceutical preparation contains calcium carbonate and citric acid. From 5-20 parts by weight of the total acid provided for the reaction with the calcium carbonate is replaced by at least one of malic acid, gluconic acid, lactic acid, and their salts. Citric acid and calcium carbonate are granulated with a partial reaction, and in each case at least part of the compound partially replacing the citric acid is granulated in solid, powdered form together with the citric acid and the calcium carbonate and/or dissolved in a granulation liquid or buffer solution.Type: GrantFiled: March 26, 1996Date of Patent: June 2, 1998Assignee: Gerhard GergelyInventors: Gerhard Gergely, Thomas Gergely, Irmgard Gergely, Stephen Gergely
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Patent number: 5720977Abstract: Oral water-soluble pharmaceutical compositions containing a therapeutically effective amount of a water-soluble and stable estrogen compound such as estropipate (piperazine estrone sulfate), and at least one water-soluble, pharmaceutically acceptable calcium salt in the presence of a suitable, pharmaceutically acceptable excipient. Compositions which include an organic acid and a calcium carbonate or bicarbonate compound which reacts with the organic acid when the composition is added to water to provide effervescence are preferred.Type: GrantFiled: February 1, 1996Date of Patent: February 24, 1998Inventor: Romano Deghenghi
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Patent number: 5676966Abstract: A granular additive composition for ruminant feed which stably protects a biologically active substance in the rumen of the ruminant and allows it to be effectively digested and absorbed in the digestive organs after the abomasum.Type: GrantFiled: April 19, 1995Date of Patent: October 14, 1997Assignee: Ajinomoto Co., Inc.Inventors: Nobuyoshi Kitamura, Susumu Shibahara, Toru Ikeda
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Patent number: 5662935Abstract: An improved process for preparing controlled release pharmaceutical forms comprises exposing a mixture comprising one or more excipients and one or more active ingredients compatible with each other and with said excipients to mechanical or electromechanical actions for a well established time and within a wide range of frequencies to give tablets, matrices or mono or multilayered films. Said forms can be optionally crushed to give a granulate or powder. Depending on the employed excipient, a delayed or rapid but always controllable release of the active ingredient can be attained.Type: GrantFiled: June 23, 1995Date of Patent: September 2, 1997Assignee: Saitec S.R.L.Inventor: Giuseppe Motta
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Patent number: 5660860Abstract: A water-dispersible tablet comprises acyclovir and a dispersing agent. The dispersing agent is a swellable clay such as a smectite, e.g. Veegum F or bentonite, and is generally present within the granules of the tablet to provide a tablet which is capable of dispersing in water within 3 minutes to provide a dispersion which will pass through a 710 .mu.m sieve. The tablet can be optionally film-coated in which case the dispersion time is less than 5 minutes.Type: GrantFiled: October 3, 1994Date of Patent: August 26, 1997Assignee: Glaxo Wellcome Inc.Inventor: Krystyna Elzbieta Fielden
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Patent number: 5648390Abstract: A method has been discovered for repelling ants by treating objects or areas with effective amounts of compositions that include (a) one or more C.sub.6 to C.sub.8 carboxylic acids; (b) one or more C.sub.6 to C.sub.14 alcohols; (c) one or more esters which are reaction products of (a) and (b) or an ester which is a reaction product of the repellents and other carboxylic acids or alcohols; (d) one or more C.sub.6 to C.sub.11 carboxylic acid esters; (e) one or more C.sub.6 to C.sub.14 ketones; or (f) mixtures thereof.Type: GrantFiled: August 4, 1994Date of Patent: July 15, 1997Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Robert K. Vander Meer, William A. Banks, Clifford S. Lofgren
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Patent number: 5626878Abstract: A medicament adsorbate containing corn syrup having contained therein from about 10 to about 90% by weight of the adsorbate of a medicament drug a magnesium trisilicate having a surface area of at least 400 m.sup.2 /g and having a structure with multiple interstitial spaces, and having adsorbed therein from about 0.5 to about 30% by weight of the adsorbate of a medicament drug, wherein the medicament drug is an antihistamine. A reduction in the electrostatic forces between adsorbates is experienced due to the particle size of the adsorbate being in the range greater than 40 to about 800 um, most of the adsorbates prepared being a particle size greater than 150 um, which allows for better processing.Type: GrantFiled: January 10, 1995Date of Patent: May 6, 1997Assignee: Warner Lambert CompanyInventors: Felipe Garay, Stanley Lech, Mark Oehling
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Patent number: 5624677Abstract: A composition providing a relatively slow release of water-soluble drugs, such as apomorphine, for delivery via the sublingual or buccal routes.Type: GrantFiled: June 13, 1995Date of Patent: April 29, 1997Assignee: Pentech Pharmaceuticals, Inc.Inventors: Ragab El-Rashidy, Bruce Ronsen, Emad E. Hassan
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Patent number: 5624683Abstract: A sustained-release multi-granule tablet is obtained by compressing sustained-release granules, which contains a basis, and a formulation adjuvant. Each of the granules has been coated in advance with a layer of the formulation adjuvant and/or a layer of a mixture of the formulation adjuvant and the basis. The tablet releases an active substance at a suitable velocity into the digestion tract, resulting in that the inbalance in the absorption of the drug in each patient and among individual patients is minimized to achieve maximum bioavailability.Type: GrantFiled: February 7, 1994Date of Patent: April 29, 1997Assignee: Eisai Co., Ltd.Inventors: Hidenobu Andoh, Sumio Watanabe, Yasuo Miyake
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Patent number: 5604208Abstract: An antibiotic formulation comprising gentamicin, and optionally tetracycline or oxytetracycline, for use in plants.Type: GrantFiled: January 30, 1995Date of Patent: February 18, 1997Assignee: Quimica Agronomica de Mexica, S.de.R.L.MI.Inventor: Miguel E. Alvarado-Licon
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Patent number: 5597575Abstract: This application proposes a new topical treatment for the stimulation and induction of hair growth as well as for preventing further hair loss. These pharmacologic results would be achieved by stimulation of an inactive hair follicle or by reversing the dysfunction of the hair follicles or by improvement of the general physiologic state of the scalp skin. It would also stimulate the maturation and differentiation of those cells specifically involved in hair growth either directly or by stimulating the organelles and supporting structures associated with the hair follicle. The topical composition comprises vitamin D.sub.3 or various nitro-benzoic acids esters thereof, or the biologically active metabolites of vitamin D.sub.3 preferabiy affixed, during preparation to microparticulate charged non-metaliic microparticles and aloe. The final concentration of vitamin D.sub.3 in the composition is 0.5% or 500,000 IU by volume.Type: GrantFiled: June 6, 1994Date of Patent: January 28, 1997Inventor: Richard Breitbarth
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Patent number: 5595762Abstract: Stabilized pulverulent active agents, compositions containing them and also process for obtaining them; such stabilized active agents enable dry and stable pharmaceutical, dietary, nutritional or cosmetic compositions to be obtained, in which the properties of the said active agents are neither modified nor impaired. Such stabilized active agents are stabilized by coating with a coating composition comprising:-- at least one film-forming agent, in proportions of between 2 and 25% by weight of the final mass, selected from polyvinylpyrrolidones (povidone), polyvinyl alcohols, vinylpyrrolidone/vinyl acetate copolymer, vinylpyrrolidone/polyvinyl alcohol copolymer, cellulose derivatives such as cellulose acetate, cellulose acetate phthalate, cellulose butyrate, ethylcellulose and methylcellulose, acrylic and methacrylic polymers and copolymers and vegetable, animal or synthetic waxes, and-- at least one pore-forming agent, in proportions of between 0 and 5%, by weight preferably of between 0.Type: GrantFiled: November 30, 1993Date of Patent: January 21, 1997Assignee: Laboratoires VirbacInventors: Guy Derrieu, Bernard Raynier
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Patent number: 5589159Abstract: A method for treating hypersensitive teeth by treating the teeth with an oral composition comprising hectorite clay, especially Laponite clay.Type: GrantFiled: April 11, 1995Date of Patent: December 31, 1996Assignee: Block Drug Company Inc.Inventors: Kenneth Markowitz, Mikhail Y. Gelfer
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Patent number: 5576021Abstract: A sustained-release multi-granule tablet is obtained by compressing sustained-release granules, which contains an active substance, and a formulation adjuvant. Each of the granules has been coated in advance with a layer of the formulation adjuvant and/or a layer of a mixture of the formulation adjuvant and the active substance. The tablet releases an active substance at a suitable velocity into the digestion tract, resulting in that the variability in the absorption of the drug in each patient and among individual patients is minimized to achieve maximum bioavailability.Type: GrantFiled: July 15, 1994Date of Patent: November 19, 1996Assignee: Eisai Co., Ltd.Inventors: Hidenobu Andoh, Sumio Watanabe, Yasuo Miyake
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Patent number: 5574006Abstract: A physiologically active peptide composition having a physiologically active peptide dispersed homogeneously in and adsorbed homogeneously onto a unique carrier. The physiologically active peptide composition contains a physiologically effective amount of the physiologically active peptide dispersed homogeneously in and adsorbed homogeneously onto hydroxyapatite. The composition is nasally administrable in powdery form.Type: GrantFiled: October 18, 1994Date of Patent: November 12, 1996Assignee: Dott Research LaboratoryInventor: Akira Yanagawa
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Patent number: 5543393Abstract: The present invention relates to a cyclosporin-containing powder composition which comprises cyclosporin, a non-ionic hydrophilic surfactant and a porous carrier. In addition, the present invention relates to a method for preparing the cyclosporin-containing powder composition which comprises dissolving cyclosporin and a non-ionic hydrophilic surfactant in an organic solvent, adding a porous carrier to the resulting solution and then evaporating the organic solvent from the mixture. The powder composition of the present invention is stable and does not require a special manufacturing technique when it is formulated. In addition, since the powder composition of the present invention does not contain an organic solvent, the necessity of a special package is excluded. Furthermore, the composition of the present invention provides an improved bioavailability which results in decrease of a single dosage, and therefore, can contribute to the alleviation of the side effects associated with cyclosporin.Type: GrantFiled: November 23, 1994Date of Patent: August 6, 1996Assignee: Chong Kun Dang Corp.Inventors: Jung W. Kim, Hee J. Shin, Joon K. Park, Kyeong B. Min
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Patent number: 5518986Abstract: The present invention provides an effective method for controlling foliage and root fungus infection in cultivated crops. A fungicide composition in the form of an aqueous formulation which is applied to pre-harvest crops contains ingredients such as pentachloronitrobenzene, sodium bicarbonate, sodium carbonate, potassium oleate, potassium octanoate and xanthan gum. The combination of potassium oleate, potassium octanoate and xanthan gum functions as an effective spreader-sticker medium for forming an adherent coating on plant foliage surfaces, and for saturating ground soil. The coating exhibits both immediate and long duration fungicidal activities.Type: GrantFiled: April 6, 1995Date of Patent: May 21, 1996Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5518987Abstract: The present invention provides an effective method for controlling foliage and root fungus infection in cultivated crops. A fungicide composition in the form of an aqueous formulation which is applied to pre-harvest crops contains ingredients such as etridiazole, potassium bicarbonate, sodium carbonate, potassium oleate, potassium caprylate and xanthan gum. The combination of potassium oleate, potassium caprylate and xanthan gum functions as an effective spreader-sticker medium for forming an adherent coating on plant foliage surfaces, and for saturating ground soil. The coating exhibits both immediate and long duration fungicidal activities.Type: GrantFiled: October 3, 1995Date of Patent: May 21, 1996Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5512300Abstract: A method for preparing ibuprofen granulations which exhibit improved stability and resistance to the formation of low melting point eutectics is disclosed. The method includes forging an amalgamation of ibuprofen and an alkali metal in a physical matrix which is suitable for inclusion in a composition without destroying the amalgamation. The stabilized ibuprofen granulation can be combined with other active ingredients and/or excipients to form compositions which have extended shelf life and are resistant to the formation of low melting point eutectics.Type: GrantFiled: September 15, 1992Date of Patent: April 30, 1996Assignee: Warner-Lambert CompanyInventors: Timothy H. Weng, Michael G. Williams
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Patent number: 5508043Abstract: The controlled release of therapeutically active agents is achieved from a controlled release matrix of sodium alginate and a calcium salt. When the composition is to be administered rectally, the matrix is combined with a therapeutically active agent and a suitable suppository base. When the composition is to be administered orally, the matrix further includes a higher aliphatic alcohol.Type: GrantFiled: February 21, 1995Date of Patent: April 16, 1996Assignee: Euro- Celtique, S.A.Inventor: Thinnayam N. Krishnamurthy
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Patent number: 5490987Abstract: The present invention provides a novel formulation of matter and a novel process for making it. In particular, the present invention provides unique and novel 1000 mg tablets of Colestipol hydrochloride having the advantageous properties of hardness and low friability and a novel process for making such tablets.Type: GrantFiled: December 30, 1993Date of Patent: February 13, 1996Assignee: The Upjohn CompanyInventors: Robert W. Shen, Jeffrey E. Price
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Patent number: 5484800Abstract: The present invention is directed to liquid medicinal suspension compositions for the administration of doses of active pharmaceutical agents such as H.sub.2 -antagonists. H.sub.2 -antagonists are known for their adverse taste and/or malodor and the claimed suspension functions to mask the adverse taste and odor of such active ingredients. Also disclosed are liquid medicinal compositions comprising the claimed suspension composition and the H.sub.2 -antagonist active ingredients.Type: GrantFiled: August 30, 1994Date of Patent: January 16, 1996Assignee: American Home Products CorporationInventors: Robert G. Blank, Annabelle Mogavero, Alexander Seabrook
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Patent number: 5482720Abstract: This invention provides an encapsulated co-micronized bicarbonate salt powder composition which is a blend of crystalline ingredients having a particle size between about 0.1-30 microns. The composition is produced by mill co-micronization of a crystalline bicarbonate ingredient and a crystalline inorganic compound ingredient having a Mohs hardness value between about 3-7, and then surface coating the particles with a polymer. A blend of crystalline particles such as sodium bicarbonate and zinc oxide is free-flowing and essentially free of agglomerated solids after co-micronization, and the discrete crystalline particles are coated with a polymer to form a present invention encapsulated co-micronized bicarbonate salt powder composition.Type: GrantFiled: October 11, 1994Date of Patent: January 9, 1996Assignee: Church & Dwight Co., Inc.Inventors: Richard T. Murphy, Wolfgang R. Bergmann
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Patent number: 5472938Abstract: The present invention relates to aqueous depot formulations of hirudin, particularly desulphatohirudin, which are very stable. These formulations contain water, hirudin, and calcium, magnesium, or zinc ions in the form of water insoluble salts, the salts being in a concentration of from 100 mM to 600 mM.Type: GrantFiled: February 17, 1994Date of Patent: December 5, 1995Assignee: Ciba-Geigy CorporationInventor: Tudor Arvinte
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Patent number: 5468716Abstract: The present invention provides a fungicide composition which contains ingredients which are biocompatible for purposes of agricultural applications, and which are harmless to animals and humans. An invention fungicide composition in the form of a dry blend formulation remains non-caking and free-flowing under storage conditions. Illustrative of an invention fungicide composition is a formulation which has a content of sodium bicarbonate, potassium bicarbonate, xanthan gum, dialkylsulfosuccinate salt and alkyl sulfate salt surfactants, and magnesium silicate anti-caking ingredient. The xanthan gum and surfactants function as an effective spreader-sticker and film-forming medium when the composition is diluted with water for agricultural applications.Type: GrantFiled: October 3, 1994Date of Patent: November 21, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5468473Abstract: An aqueous alcohol carrier solvent based antiperspirant composition which does not contain silicone products and which forms a thick lotion for use on the hands and feet. The composition includes a thickener--absorber mixture of hydroxylalkylcellulose, preferably hydroxypropylmethylcellulose, with colloidal silica and silicates and an antiperspirant active material, preferably chlorhydrol. A preferred embodiment includes the addition of Tea Tree Oil to the formulation. The antiperspirant composition reduces sweating on the hands and feet and is nonirritating, nontacky and mildly soothing to the skin.Type: GrantFiled: February 9, 1994Date of Patent: November 21, 1995Assignee: Innova Products, Inc.Inventor: Patricia Mullen
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Patent number: 5462750Abstract: A biologically active composition made up of core particles having diameters of less than about 1000 nanometers which are coated with a layer which is designed to allow attachment of biologically active proteins, peptides or pharmacological agents to the microparticles. When viral protein is attached to the core particles, the result is a viral decoy which accurately mimics the native virus in both size and structure while being entirely devoid of virulent activity due to the microparticle core. Other antigenic proteins or peptides are attached to provide molecules which are useful in raising antibodies or as a diagnostic tool. Further, pharmacological agents are attached to the microparticles to provide pharmaceutical compositions.Type: GrantFiled: April 8, 1994Date of Patent: October 31, 1995Assignee: The Regents of the University of CaliforniaInventors: Nir Kossovsky, Rointan F. Bunshah
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Patent number: 5459122Abstract: An aromatic oil having an aniline point less than 120.degree. F., a mutagenicity index based on The Modified Ames Test of less than 2.0, a benzene, naphthalene and methyl substituted benzenes and naphthalenes individual component concentrations less than 100 wppm, and a clay gel aromatics fraction content of at least 50 weight % based on aromatic oil, said aromatics fraction characterized in that it has a naphthene-benzenes and dinaphthenebenzenes content of at least 50 volume % based on aromatics fraction. The invention also relates to a process for preparing the aromatic oil which comprises the steps of selective solvent extraction, selective distillation and two-stage hydrotreating with removal of hydrogen sulfide and/or ammonia. The aromatic oils are useful in agricultural formulations due to their low environmental impacts.Type: GrantFiled: April 26, 1994Date of Patent: October 17, 1995Assignee: Exxon Research & Engineering Co.Inventors: Thomas J. Ford, Gilbert V. Chambers
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Patent number: 5444096Abstract: An anhydrous, topically-effective composition that resists phase separation and exhibits improved properties comprising a topically-active compound, such as an astringent salt; an improved suspending agent comprising a finely-divided silica and a suspending wax composition; and a suitable volatile liquid carrier, such as a volatile silicone or a volatile hydrocarbon. The suspending wax composition comprises a wax, an ester including at least 10 to about 32 carbon atoms and a volatile liquid carrier. The anhydrous, topically-effective composition is useful in topical cosmetic and medicinal preparations, such as antiperspirants, sunscreens and topical drug products, and is especially useful in cosmetic and medicinal preparations wherein an insoluble topically-active compound is dispersed throughout a liquid phase.Type: GrantFiled: November 9, 1993Date of Patent: August 22, 1995Assignee: Helene Curtis, Inc.Inventors: Andrew D. McCrea, Michael P. Diulus
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Patent number: 5432146Abstract: The present invention provides a fungicidal fertilizer composition which contains ingredients which are biocompatible for purposes of agricultural applications, and which are harmless to animals and humans. An invention fungicide composition in the form of a dry blend formulation remains non-caking and free-flowing under storage conditions. Illustrative of an invention fungicide composition is a formulation which has a content of sodium bicarbonate, potassium bicarbonate, potassium oleate, xanthan gum and a fertilizer-effective content of nitrogen, phosphorus and potassium elements. The combination of potassium oleate and xanthan gum functions as an effective spreader-sticker and film-forming medium when the composition is diluted with water for agricultural applications. When the aqueous medium is hard water, calcium oleate is formed which enhances the sticker properties of the aqueous fungicide composition in agricultural applications.Type: GrantFiled: December 20, 1993Date of Patent: July 11, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5427772Abstract: The use of acyl lactylates having a C.sub.4 to C.sub.16 acyl group or of compositions containing such acyl lactylates to enhance the elasticity of skin, is provided.Type: GrantFiled: October 21, 1993Date of Patent: June 27, 1995Assignee: Elizabeth Arden Co., Division of Conopco, Inc.Inventor: Desmond B. Hagan
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Patent number: 5415877Abstract: The present invention provides a fungicide composition which contains ingredients which are biocompatible for purposes of agricultural applications, and which are harmless to animals and humans. An invention fungicide composition in the form of a dry blend formulation remains non-caking and free-flowing under storage conditions. Illustrative of an invention fungicide composition is a formulation which has a content of sodium bicarbonate, potassium bicarbonate, xanthan gum, dialkylsulfosuccinate salt and alkyl sulfate salt surfactants, and magnesium silicate anti-caking ingredient. The xanthan gum and surfactants function as an effective spreader-sticker and film-forming medium when the composition is diluted with water for agricultural applications.Type: GrantFiled: December 22, 1993Date of Patent: May 16, 1995Assignee: Church & Dwight Co., Inc.Inventor: Anthony E. Winston
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Patent number: 5401515Abstract: Aqueous coating compositions for forming elastomeric films around active cores (e.g., drugs) comprising a dispersion of pre-crosslinked polyorganosiloxane latex particles, colloidal silica particles, and a water-dispersible organic material (e.g., polyethylene glycol) are disclosed and claimed. The elastomeric films formed by the coating compositions are used to control the rate of release of an active agent in the cores into an aqueous environment. Methods of formulating the coating compositions and active cores coated with the coating compositions are also disclosed.Type: GrantFiled: January 28, 1994Date of Patent: March 28, 1995Assignee: Dow Corning CorporationInventors: John T. Woodard, Martin C. Musolf, Patrick J. Miller
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Patent number: 5395615Abstract: A pharmaceutical composition of a free amine benzophenanthridine alkaloid and a pharmaceutically acceptable carrier is disclosed. The composition is an antibacterial and antifungal agent.Type: GrantFiled: September 30, 1992Date of Patent: March 7, 1995Assignee: Vipont Pharmaceutical, Inc.Inventors: Kenneth C. Godowski, Ronald J. Harkrader, Richard L. Dunn, Arthur J. Tipton
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Patent number: 5395851Abstract: A coating composition for application to tree wounds, such as pruning wounds of living trees is provided. The composition is non-phytotoxic and provides extended protection against fungal pathogens. The coating composition comprises a liquid carrier together with a fatty acid metal salt active ingredient. Exemplary fatty acid metal salts include those prepared from alpha monocarboxylic acids having from 4 to 18 carbon atoms and a compound containing a metal selected from the group consisting of calcium, copper, iron, magnesium, and zinc. Various additives can be included within the composition, including gum-like substances and binders suitable to facilitate the adhesion of the active ingredient to the tree surface, as well as defoaming agents and other formulation enhancing agents.Type: GrantFiled: July 16, 1993Date of Patent: March 7, 1995Assignee: W. Neudorff GmbH KGInventor: Frederick S. Sedun
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Patent number: 5382433Abstract: Cosmetic formulations have activatable dormant pigments dispersed in an anhydrous base or vehicle. Shear forces applied to the cosmetic formulation following application to the skin causes activation of the dormant pigment thereby releasing the pigment and giving the original color of the anhydrous base or vehicle renewed intensity or a "long wearing" affect.Type: GrantFiled: January 21, 1994Date of Patent: January 17, 1995Assignee: Avon Products, Inc.Inventors: Harold E. Pahlck, Shari R. Martin, Michael E. Squires
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Patent number: 5356617Abstract: New cosmetic raw materials are provided in the form of complexes of pigment materials coupled to small microspheres providing complexes that impart richness and feel, with low oil absorbency while displaying the optical and other properties of the pigment. Improvements in spatial disposition of small pigment particles provide a better dispersion of pigment in and products such as makeups, creams, lipsticks, blushers, nail enamels, and the like. Preferred embodiments include talc, nylon, silica, starches and iron oxide pigments coupled by a liquid titanate coupling agent to microspheres of polyvinylidene chloride copolymer, polyethylene, nylon and silica. Simple methods of manufacture include spraying a liquid titanate in solution on a blended mixture of pigment and microsphere and drying the product while blending, to cure it.Type: GrantFiled: December 7, 1992Date of Patent: October 18, 1994Assignee: Kobo Products, Inc.Inventor: David S. Schlossman
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Patent number: 5326560Abstract: An insecticide carrier and insecticide comprising a mixture of petrolatum and diatomaceous earth. A diluent, such as crop oil, may be added to the mixture, particularly for use as a spray insecticide. Any of a variety of insecticides containing active ingredients may also be added. The resulting formulation provides a longer life product, as well as ultraviolet shielding, good adhesion to insects and vegetation, and increased insect penetration.Type: GrantFiled: April 20, 1993Date of Patent: July 5, 1994Inventor: Jack A. Henderson
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Patent number: 5326573Abstract: In the combating of agricultural and horticultural pests by applying to a locus from which it is desired to exclude such pests a normally liquid active compound and a normally solid active compound, the improvement which comprises applying such active compound in the form of granules comprisinga) carrier granules having a non-absorptive surface,b) at least one liquid active compound and at least one solid active compound,c) at least one adhesive based on polyurethane as a binder, optionally mixed with a further adhesive selected from the group consisting of polyvinyl acetate, polyvinylpyrrolidine, polyvinyl alcohol, vinyl acetate/di-n-butyl maleate copolymers, acrylic acid ester, vinyl acetate/ethylene, vinyl acetate/ethylene/vinyl chloride, vinyl acetate/acrylic acid ester, vinyl acetate/vinyl ester and styrene/acrylic acid ester, andd) optionally an additive.Type: GrantFiled: February 23, 1993Date of Patent: July 5, 1994Assignee: Bayer AktiengesellschaftInventors: Elmar Antfang, Dimitrios Kerimis, Rolf-Jurgen Singer