Abstract: A skin cream composition of the present invention comprises: water, and emulsified and dispersed in the water: (1) a protein complex comprising serum proteins and hydrolyzed animal proteins; (2) a protein-amino acid-vitamin-nucleotide complex comprising proplylene glycol, serum proteins, niacinamide, water, adenosine phosphate, and arginine; and (3) dimethylsilanoyl hyaluronate complex, and the dimethylsilanoyl hyaluronate are each present in cosmetically effective quantities. Preferably, the skin cream composition further comprises a highly stable micellar complex.

Abstract: Disclosed is a composition for bonding separated tissues together or for coating tissues or prosthetic materials including at least one natural or synthetic peptide and at least one support material which may be activated by energy.

Abstract: Binary polymer mixtures of albumin and glycosaminoglycan and ternary polymer mixtures of polyionic polypeptide and high molecular weight and highly charged polyanions are useful for managing skin including wrinkles or other irregularities. Aqueous compositions of the ternary mixtures have pH dependent phase change properties and provide skin activated films.

Abstract: Compositions and methods for treating bacterial infections are disclosed. Compositions of a quinolone carboxylic acid or a pharmaceutically acceptable salt or metal ion-acid complex thereof and a polymeric additive that reduces vein irritation upon infusion are described and utilized as antibacterial agents. The compositions of the present invention are parenterally administered to a patient.

Abstract: A readily dissolvable carrier material having sufficient rigidity for administration of drugs, nutrients, vitamins, biologically-active materials, foodstuffs and combinations thereof capable of rapid dissolution by saliva, bodily fluids or other liquid comprising an interim skeletal structure of a watersoluble, hydratable gel or foam forming material, preferably a proteinaceous material, such as with maltodextran, in the hydrated state and dehydrated to leave spaces in place of hydration water. On dissolution by saliva, bodily fluids or other liquids, the composition becomes a liquid system. While the oral route is preferred, other routes may be used to administer the compositions of this method.

Abstract: A powdery complex is obtained by combining a useful substance such as vitamin E and liquid fatty oil with albumin. This powdery complex has excellent storage stability and can keep the useful substance contained therein stably for a long time.

Abstract: The pharmaceutical composition of the present invention is a pharmaceutical composition of high drug content containing 1-200 parts by weight of a drug having a protein binding property and 100 parts by weight of albumin.This pharmaceutical composition is produced by stirring the drug and albumin of the above proportions at a high speed in an aqueous solvent and then removing the solvent by distillation, and has effects of alleviating the side effect of the drug used therein and also of improving the absorption, light stability, etc. of the drug.

Abstract: A readily dissolvable carrier material having sufficient rigidity for administration of drugs, nutrients, vitamins, biologically-active materials, foodstuffs and combinations thereof capable of rapid dissolution by saliva, bodily fluids or other liquid comprising an interim skeletal structure of a water-soluble, hydratable gel or foam forming material, preferably a proteinaceous material, such as gelatin, that has been hydrated, rigidified, such as with maltodextrin, in the hydrated state and dehydrated to leave spaces in place of hydration water. On dissolution by saliva, bodily fluids or other liquids. The composition becomes a liquid system. While the oral route is preferred, other routes may be used to administer the compositions of this method.

Abstract: A liquid coacervate composition and a method of introducing heme, hemoproteins and/or heme-hemoprotein complexes into the body. The liquid composition, comprising an oxygen-carrying molecule containing iron and a two-phase aqueous coacervate system, can be administered orally or intraveneously. The liquid composition is utilized to augment the oxygen transport capability of the body, to treat for several of the anemias and/or to act as an oxygen-carrying plasma volume extender.

Abstract: Provided is a cosmetic compositiom which beautifies and moisturizes the skin of a human being. The composition may also have therapeutic effects on the human skin such as the removal of lines or wrinkles, dissolution of fat pockets, the removal of bags under the eyes, and the closing of pores or gaps in the skin to render a smooth uniform appearance. The composition is comprised of seven basic ingredients, which include:live yeat cells,selenium,carotene,RNA,DNA,water andalbumen.These core ingredients generally make up from about 80% to 100% of the composition used in the treatment, and are the basis for the advantages realized thereby. Significant and long-lasting results are particularly achieved upon application of the composition to the human skin with exposure to sunlight.

Abstract: A method of preventing erythropoietin in an aqueous solution from being adsorbed on the inner surface of the wall of a container by incorporating in the aqueous solution one or more additives, and an erythropoietin composition so formulated as to avoid the adsorption of erythropoietin onto the inner surface of the wall of a container are disclosed.The additives which are useful in this invention include human serum albumin, bovine serum albumin, lecithin, dextrans, ethylene oxide-propylene oxide copolymers, hydroxypropyl cellulose, methylcellulose, polyoxyethylene hydrogenated castor oils, polyethylene glycols and the like.

Abstract: The invention provides an immunizing agent or preparation e.g. a vaccine for parenteral administration comprising particles of coalesced and covalently interlinked physiologically compatible proteinaceous molecules and, entrapped in these particles, an immunogen adapted to be released by the gradual proteolysis of the particles and, when so released, being of sufficient size to elicit an immuno response to characteristic immunogenic determinants of the immunogen. The proteinaceous molecules are preferably homotypic for the animal to be immunized. Preferably, the particles or molecules carrying the immunogenic determinants are crosslinked to the proteinaceous molecules.

Abstract: Parenteral solutions comprising(a) a sparingly soluble medicament active compound,(b) a solvent consisting of(i) 5-100 M/V % of an organic solvent or of a mixture of organic solvents and(ii) 0-95 W/V % of water,(c) A 0.5-30 W/V % strength aqueous solution of a human serum protein and customary auxiliaries and/or excipients, 1 to 40,000 parts by weight, preferably 25 to 30,000 parts by weight of solvent (b) and 1 to 1,000,000 parts by weight, preferably 50 to 40,000 parts by weight, of human serum protein solution (c) being present per part by weight of medicament active compound.The sparingly soluble medicament active compounds which can be used have a solubility in water of between 1 .mu.g and 10 g, preferably between 10 .mu.g and 1 g per liter of water. Examples of such medicaments are dihydropyridine compounds and pyrazolones, and muzolimine.

Abstract: The present invention provides for an oral drug delivery system based on a two phase liquid coacervate system prepared from water and one or more surfactants selected from anionic, cationic, amphoteric, and non-toxic surfactants, polysaccharides, synthetic polymers and polysorbates and their derivatives, and in which a pharmaceutical component is incorporated. The delivery system may be prepared in the form of a microemulsion as well as other forms including encapuslated microparticles. The claimed oral composition is useful to delivery oral dosage forms of drugs, their salts and derivatives thereof; biologicals, enzymes, and other pharmocologically active compositions. A method to prepare the oral drug delivery system is also disclosed.

Abstract: Porcine serum albumin stabilizes porcine growth hormone, and provided for sustained release of porcine growth hormone in implant devices for swine.

Abstract: According to the invention there are provided a quail egg based stabilized foam composition for cosmetic purposes comprising 5-75% by weight of quail egg, 20-80% by weight of one or more carrier/s/, 0-40% by weight of one or more additive/s/, 0.1-1% by weight of one or more antiseptic agent/s/ and 1-3% by weight of one or more sulfonamide/s/ potentiated with 2,4-diamino-5-/3',4',5'-trimethoxybenzyl/pyrimidine in a weight ratio of /1:5/-/5:1/, furthermore 5-20% by weight of a propellant.The compositions of the present invention can be stored for a very long period of time without decomposition due to their excellent stability.

Abstract: This invention relates to a cosmetic composition of the oil-in-water type comprising an oily substance having no free carboxyl group, water, and an emulsifier composed of either a combination of a basic polypeptide and a higher fatty acid or a salt (soap) formed from these compounds. This cosmetic composition using such an emulsifier derived from naturally occurring materials causes no irritation to the skin, as contrasted with cosmetic compositions using synthetic emulsifiers. In addition, it shows excellent emulsion stability and storage stability, gives an agreeable feeling, and presents an attractive appearance (fine texture and good gloss).