Designated Organic Nonactive Ingredient Containing Other Than Hydrocarbon Patents (Class 514/772)
  • Patent number: 10251844
    Abstract: A substantially solvent-free matrix layer containing (?)-5,6,7,8-tetrahydro-6-[propyl-[2-(2-thienyl)ethyl]amino]-1-naphthalenol is produced by adding an active substance to an adhesive solution, coating the resultant active substance-containing adhesive solution onto a suitable sheet, and removing the solvents in a drying process to give said substantially solvent-free matrix layer.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: April 9, 2019
    Assignees: LTS LOHMANN THERAPIE-SYSTEME AG, UCB MANUFACTURING IRELAND LIMITED
    Inventors: Walter Müller, James V. Peck
  • Patent number: 10213418
    Abstract: Uses of pharmaceutical compositions comprising berberine for treatment of dermatologic toxicities and other skin disorders.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: February 26, 2019
    Assignee: TWi Biotechnology, Inc.
    Inventors: Po-Yuan Tseng, Carol Oscar Brown, III, I-Yin Lin, Chen-En Tsai, Chih-Kuang Chen
  • Patent number: 10054548
    Abstract: The pH sensing biofilms include anthocyanin and a cellulose nanostructure or a cellulose nanocomposite. The cellulose nanostructure can include cellulose nanofibrils. The cellulose nanocomposite can include a composite of cellulose nanofibrils and pectin or a composite of cellulose nanofibrils and alginate. The presence of the anthocyanin in the biofilm allows the biofilm to change color in response to pH changes, thereby allowing the biofilm to be used as an active visual indicator of decay.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: August 21, 2018
    Assignee: King Saud University
    Inventors: Ali Abdullah Alshatwi, Jegan Athinarayanan, Periasamy Vaiyapuri Subbarayan
  • Patent number: 10028506
    Abstract: The present invention relates to a plant strengthener in the form of a formulation comprising tocopherol or a derivative of a tocopherol, and to the use thereof for increasing the tolerance of crop plants to stress events, in particular to chemically induced stress, cold-induced stress, drought-induced stress or light-induced stress. The plant strengtheners are present in the form of formulations which comprise the following components A, B and C: a) at least one tocopherol or derivative of a tocopherol (component A); b) at least one nonionic emulsifier (component B); and c) at least one water-soluble boron compound (component C), and, if appropriate, d) one or more UV absorbers (component D) and e) one or more organic solvents.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: July 24, 2018
    Assignee: COMPO EXPERT GMBH
    Inventors: Georg Ebert, Christian Jaeger
  • Patent number: 9993401
    Abstract: The invention provides a benefit agent delivery particle having an average diameter of less than 50 micron comprising; at least one shell formed by a step-growth polymerization reaction, preferably involving an isocyanate monomer, more preferably a urethane and/or a urea. interior said shell, at least one region formed by chain-growth polymerization reaction (preferably a free-radical polymerization) which does not involve an isocyanate, c) optionally, a benefit agent interior to said shell, and/or a deposition aid exterior to said shell. The invention further provides a process for the preparation of such particles wherein the shell is formed prior to the chain-growth polymerization of the at least one region interior of the shell, preferably be forming the shell at a temperature at which the chain-growth reaction is inhibited.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: June 12, 2018
    Assignee: Conopco, Inc.
    Inventors: Stuart Anthony Barnett, Craig Warren Jones, Adam John Limer, James Merrington, Jeremy Nicholas Winter
  • Patent number: 9944754
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Grant
    Filed: September 28, 2016
    Date of Patent: April 17, 2018
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Joseph Edward Semple, Tomas Vojkovsky
  • Patent number: 9877971
    Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising non-systemic corticosteroid soft lozenges, methods for making the same, and methods for treating subjects in need thereof with such lozenges. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the oral pharmaceutical compositions comprise chewable, suckable, or buccally-dissolvable soft lozenges for the treatment of esophageal lesions. The soft lozenges provide topical, non-systemic delivery of corticosteroids to the esophagus and oral cavity.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: January 30, 2018
    Assignee: Banner Life Sciences LLC
    Inventors: Yinyan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
  • Patent number: 9867834
    Abstract: Described herein are topical, non-systemic, slow releasing oral pharmaceutical compositions, methods for making the same, and methods for treating subjects in need thereof with such compositions. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the pharmaceutical composition provides topical corticosteroids to the esophagus and oral cavity.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: January 16, 2018
    Assignee: Banner Life Sciences LLC
    Inventors: Yinyan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
  • Patent number: 9750780
    Abstract: The invention provides a primary carotenoid-containing composition comprising an aqua-containing component, a lipid-containing component and a carotenoid-containing fiber material from plant origin with lowered content of aqua-soluble substances. The invention also provides oral compositions that comprise the primary composition in a foodstuff, in a food supplement or in a pharmaceutical preparation.
    Type: Grant
    Filed: June 25, 2012
    Date of Patent: September 5, 2017
    Inventor: Dmitry Druzhinin
  • Patent number: 9750707
    Abstract: Compositions are provided that contain a TRPV1 agonist, such as capsaicin, and a solvent system. Topical application of the composition results in rapid delivery of agonist to the dermis and epidermis. Method of using the compositions for reducing nociceptive nerve fiber function in subjects, and for treatment of capsaicin-responsive conditions are also provided.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: September 5, 2017
    Assignee: ACORDA THERAPEUTICS, INC.
    Inventors: Naweed Muhammad, Gene Curtis Jamieson, Keith R. Bley, Sanjay Chanda
  • Patent number: 9670301
    Abstract: Problem: To provide a novel copolymer capable of use as a surface treatment agent which is safe and does not generate hydrogen, which has good compatibility with other cosmetic raw materials so as to be able to improve compounding stability of a cosmetic, which contributes to good water resistance, sebum resistance, gloss, feel, hair attachment ability, skin attachment ability and the like of a cosmetic, which further may be used for treatment of powders of a wide range of cosmetics, and which nearly entirely suppresses the occurrence of dispersion failure on the skin. Resolution Means: A copolymer comprising: (A) an unsaturated monomer having a carbosiloxane dendrimer structure; and (B) an unsaturated monomer having at least one hydrophilic group in the molecule. A content of the unsaturated monomer having the carbosiloxane dendrimer structure is in the range of 35 to 50% by mass of the total monomer units of the copolymer.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: June 6, 2017
    Assignee: Dow Corning Toray Co., Ltd.
    Inventors: Haruhiko Furukawa, Akito Hayashi, Tomohiro Iimura
  • Patent number: 9499665
    Abstract: The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same. Compositions herein are useful for drug-delivery applications.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: November 22, 2016
    Assignee: Intezyne Technologies, Inc.
    Inventors: Kevin Sill, Tomas Vojkovsky, Adam Carie
  • Patent number: 9480977
    Abstract: A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: November 1, 2016
    Assignee: Dow Corning Corporation
    Inventors: Kurt Brandstadt, Simon Cook, Aswini Dash, Matthew Olsen, Avril Surgenor, Richard Taylor, Binh Nguyen, Ming-Shin Tzou
  • Patent number: 9427432
    Abstract: Pharmaceutical compositions comprising berberine for treatment of skin disorders and methods of use thereof.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: August 30, 2016
    Assignee: TWi Biotechnology, Inc.
    Inventors: Pao-Li Wang, Way-Yu Lin, Chen-Mao Lin, Po-Yuan Tseng
  • Patent number: 9376416
    Abstract: Provided are: a composition containing scirpusin B, which is a composition derived from a natural material and contains scirpusin B at a high content; and a process for producing the composition containing scirpusin B.A composition containing scirpusin B is produced by the extraction from a passion fruit seed. In the extraction of scirpusin B, the passion fruit seed is crushed, and subsequently at least one solvent selected from a hydrous alcohol solvent and a hydrous ketone solvent is added to the crushed product to thereby extract scirpusin B into the solvent.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: June 28, 2016
    Assignee: MORINAGA & CO., LTD.
    Inventors: Shoko Sano, Kenkichi Sugiyama
  • Patent number: 9265708
    Abstract: Provided is a composition containing a sterol ester, which is an oil poorly soluble in water, and superior in transparency, stability, foaming property, rinsability, skin feel (during rinsing and/or after use), and emollience. A composition containing (A) a sterol ester, (B) one or more anionic surfactants selected from (B1) N-acylamino acid having a C8-22 acyl group or a salt thereof, (B2) polyoxyethylene alkyl ether sulfate or a salt thereof, (C) a betaine-type amphoteric surfactant, (D) glyceryl mono-C8-14 fatty acid ester, (E) C5-6 hydroxyalcohol, and (F) water, and having pH 4-8.
    Type: Grant
    Filed: March 23, 2015
    Date of Patent: February 23, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Rina Yumioka, Eiko Oshimura
  • Patent number: 9132091
    Abstract: The present invention relates to an oil-in-water (O/W) type nano-emulsion composition comprising an oil component containing oil and a polyethylene glycol ester-based emulsifier; and a water component containing a polyol or a polyol derivative. The present invention also relates to a cosmetic composition comprising the oil-in-water type nano-emulsion composition, and to a method for preparing the oil-in-water type nano-emulsion composition. According to the present invention, a nano-sized low-viscosity emulsion having a high inner phase can be obtained through the method that is different from the conventional methods of phase inversion temperature emulsification or high pressure emulsification, thereby significantly improving the stability of the emulsion. In addition, the nano-emulsion composition of the present invention can be added to a variety of cosmetic compositions having a variety of methods of use and can thus deliver active ingredients to the skin effectively since it has small-sized particles.
    Type: Grant
    Filed: March 22, 2011
    Date of Patent: September 15, 2015
    Assignee: Amorepacific Corporation
    Inventors: Sung Il Park, Youn Joon Kim, Sang Hoon Han
  • Patent number: 9109051
    Abstract: The present invention relates to methods of producing crosslinked hyaluronic acid microbeads, as well as the produced microbeads, said method comprising the steps of: (a) providing an aqueous alkaline solution comprising hyaluronic acid, or a salt thereof; (b) forming microdroplets having a desired size from the mixed solution of step (a) in an organic or oil phase to form a water in organic or water in oil (VWO) emulsion, wherein the amount of oil phase used is of from 20 to less than 50% by weight based on the sum of oil phase and water; (c) adding a solution comprising a crosslinking agent to the emulsion, whereby the reaction of hyaluronic acid with the crosslinking agent takes place to provide crosslinked hyaluronic acid microbeads; and (d) optionally working up the dispersion of crosslinked hyaluronic acid microbeads obtained in step (c).
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: August 18, 2015
    Assignees: EVONIK GOLDSCHMIDT GMBH, NOVOZYMES BIOPOLYMER A/S
    Inventors: Hans Henning Wenk, Mike Farwick, Sandra Nattland, Ursula Maczkiewitz, Birgitte Moelholm Malle
  • Patent number: 9085545
    Abstract: The present invention provides a novel macrocyclic compound exhibiting superior odor qualities and having a musk-like aroma, a method for producing the same, and a novel flavor or fragrance composition, and food products or beverages, fragrances or cosmetics, daily necessities or household goods and oral products using the novel macrocyclic compound. The invention relates to a compound represented by the formula (1), wherein each of wavy lines represents at least one of an E-configuration of C?C double bond and an Z-configuration of C?C double bond; m represents an integer of 0 to 10; and n represents an integer of 1 to 11, and n represents an integer of 1 to 11 when m is 0 to 4 or 6 to 10, and n is an integer of 1 or 3 to 11 when m is 5.
    Type: Grant
    Filed: February 24, 2012
    Date of Patent: July 21, 2015
    Assignee: TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Teruhiko Inaba, Kenya Ishida
  • Patent number: 9040592
    Abstract: The present invention relates to a process for preparing 4-cyclohexyl-2-methyl-2-butanol. The process comprises the following steps: a) reaction of styrene with isopropanol at elevated temperature to obtain 4-phenyl-2-methyl-2-butanol, and b) heterogeneously catalyzed hydrogenation of 4-phenyl-2-methyl-2-butanol over a catalyst suitable for ring hydrogenation of aromatics.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: May 26, 2015
    Assignee: BASF SE
    Inventors: Klaus Ebel, Stefan Rüdenauer, Ralf Pelzer, Martin Bock
  • Publication number: 20150140177
    Abstract: A liquid beverage enhancer product including a shelf-stable highly concentrated liquid flavor and color solution including at least 10% non-water solvents with humectant properties including propylene glycol, glycerol, ethanol and other alcohols. The liquid beverage enhancer product in combination with beverages or non-beverage food products. A method of enhancing a beverage by adding a liquid beverage enhancer product including a shelf-stable highly concentrated liquid flavor and color solution having at least 10% non-water solvents with humectant properties to a beverage, and enhancing the flavor and color of the beverage. A method of enhancing milk, milk substitute beverages, and protein containing products, by adding the liquid beverage enhancer product having a pH of greater than 4.6 to milk, milk substitute beverages, or protein containing products, and enhancing the flavor and color of the milk, milk substitute beverages, or protein containing products without curdling.
    Type: Application
    Filed: April 21, 2014
    Publication date: May 21, 2015
    Applicant: AMT Group, LLC dba Imbibe
    Inventors: Young Kang, Joe Farinella, Kathryn Frothingham, Justin Kozlowski, Holly Lynch, John Higgs
  • Publication number: 20150133454
    Abstract: Provided is a nanostructured mucoadhesive microparticle including a biocompatible polymer, the microparticle having a surface with a nanostructure formed thereon. The present nanostructured mucoadhesive microparticle having an increased retention time on the mucous as well as with a minimized irritation to the surface can be advantageously used as a drug delivery vehicle. Thus the increased bioavailability of a therapeutic agent administered by the present microparticle leads to an increased therapeutic efficacy, reduced dosage and reduced number of administration as well as significant cost savings and improved patient convenience resulted therefrom.
    Type: Application
    Filed: May 14, 2013
    Publication date: May 14, 2015
    Applicant: SNU R&DB FOUNDATION
    Inventors: Young Bin Choy, Chun Gwon Park
  • Publication number: 20150126964
    Abstract: It has been discovered that compositions comprising magnetically heatable entities (MHEs), therapeutic agents and optional carriers such as hydrogels can be piloted from an injection point in a blood vessel to a specific location of the blood-brain barrier (BBB) using for example, a magnetic resonance imaging (MRI) device for propelling, steering and tracking of MHEs. Once the MHEs have reached their target location at or near the desired blood vessel of the BBB, an alternating magnetic field causes the MHEs to controllably heat up, thereby reversibly increasing the permeability of the BBB and allowing the therapeutic (or cytotoxic) agent to enter brain tissue.
    Type: Application
    Filed: May 13, 2013
    Publication date: May 7, 2015
    Inventors: Sylvain Martel, Seyed Nasrollah Tabatabaei Shafie
  • Publication number: 20150125403
    Abstract: Disclosed herein are methods of reducing irritation associated with personal care and cosmetic compositions comprising 1,3-propanediol, wherein the 1,3-propanediol in said personal care or cosmetic composition has a bio-based carbon content of about 1% to 100%. In addition, it is preferred that the 1,3-propanediol be biologically-derived, and wherein upon biodegradation, the biologically-derived 1,3-propanediol contributes no anthropogenic carbon dioxide emissions to the atmosphere.
    Type: Application
    Filed: January 5, 2015
    Publication date: May 7, 2015
    Applicant: DuPont Tate & Lyle Bio Products Company, LLC
    Inventors: Melissa Joerger, Gyorgyi Fenyvesi, Raja Hari Poladi, Irwin A. Palefsky, Ann Wehner
  • Publication number: 20150119422
    Abstract: The present invention relates to solid pharmaceutical formulations based on simethicone and calcium phosphate and mannitol.
    Type: Application
    Filed: December 11, 2012
    Publication date: April 30, 2015
    Inventors: José Luis Velada, Hiteshkumar Anilkant Doshi, Anjali Rajesh Tendulkar, Vicky Shinde
  • Publication number: 20150118174
    Abstract: Provided is a fragrance composition containing a compound that is highly harmonious with other various fragrances and that can impart a stronger floral feeling by being blended. A fragrance composition containing 3,6-dimethyl-heptane-2-ol. The fragrance composition may further contain at least one selected from the group consisting of, for example, 7-methyloctane-3-ol, esters, carbonates, aldehydes, ethers, lactones, and alcohols other than 3,6-dimethylheptane-2-ol.
    Type: Application
    Filed: May 30, 2013
    Publication date: April 30, 2015
    Applicant: Kao Corporation
    Inventors: Junko Ueda, Yoshiharu Ataka, Takahiro Asada, Naotoshi Toki
  • Patent number: 9011309
    Abstract: An electromagnetic radiation activated device comprises a property changing material and at least one functionalized fullerene that upon irradiation of the functionalized fullerenes with electromagnetic radiation of one or more frequencies a thermally activated chemical or physical transformation occurs in the property changing material. The thermal activated transformation of the property changing material is triggered by the heating or combustion of the functionalized fullerenes upon their irradiation. The device can include a chemical agent that is embedded in the property changing material and is released when the material is heated by the functionalized fullerenes upon irradiation.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: April 21, 2015
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Vijay Krishna, Karl Zawoy, Brij M. Moudgil, Benjamin L. Koopman, Nathanael Ian Stevens, Kevin William Powers
  • Patent number: 9011915
    Abstract: This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local disease states.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: April 21, 2015
    Assignee: Ramscor, Inc.
    Inventors: Vernon G. Wong, Louis L. Wood
  • Patent number: 9000051
    Abstract: The present invention relates mainly to a cosmetic composition and in particular a composition for making up and/or caring for keratin material and more particularly the skin and/or the lips, including at least one supramolecular polymer and a filler with an oil uptake of greater than or equal to 1.5 ml/g.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: April 7, 2015
    Assignee: L'Oreal
    Inventors: Charlotte Feltin, Gaelle Brun
  • Patent number: 8993811
    Abstract: Described herein are mixed ethers and cosmetic and/or pharmaceutical preparations comprising mixed ethers. Certain mixed ethers have a melting range between ?25° C. and +70° C., wherein the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35 ±10° C. These mixed ethers are obtainable for example by condensation reaction of a) 25 to 90% by weight of unbranched fatty alcohols with a chain length of 12 to 19 carbon atoms; b) 5 to 50 by weight of isostearyl alcohol; c) 0 to 35% by weight of a fatty alcohol with a chain length of 20 and/or 22 carbon atoms; and d) 0 to 25% by weight of a fatty alcohol having 8 and/or 10 carbon atoms.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: March 31, 2015
    Assignee: BASF SE
    Inventors: Markus Dierker, Peter Kempers, Rolf Kawa, Stefan Brüning, Jadranka Milardovic, Burkhard Beckedahl, Eike Ulf Mahnke, Heinz-Josef Krüppel
  • Publication number: 20150087724
    Abstract: Unsaturated fatty alcohol alkoxylates, processes for making them, and methods of using them are disclosed. In one aspect, a monounsaturated fatty alcohol alkoxylate is made by reducing a metathesis-derived monounsaturated alkyl ester, followed by alkoxylation of the resulting monounsaturated alcohol. Microscopy reveals that the monounsaturated alkoxylates have isotropic and lamellar phases over a wider range of actives levels compared with their saturated analogs. This attribute expands formulating latitude for many end-use applications. The unsaturated fatty alcohol alkoxylates are valuable in, for example, agricultural solvents, nonionic emulsifiers for agricultural compositions, hard surface cleaners, laundry detergents, specialty foams, additives or surfactants for paints or coatings, and surfactant compositions for enhanced oil recovery.
    Type: Application
    Filed: March 13, 2013
    Publication date: March 26, 2015
    Inventors: David R. Allen, Marcos Alonso, Mary Beddaoui, Randal J. Bernhardt, Aaron Brown, Xue Min Dong, Wilma Gorman, John Hutchison, Gary Luebke, Renee Luka, Franz Luxem, Andrew D. Malec, Ronald A Masters, Dennis S Murphy, Patti Skelton, Brian Sook, Chris Spaulding, Michael Wiester, Patrick Shane Wolfe
  • Patent number: 8986728
    Abstract: The present invention provides an implantable device having a biosoluble coating or a biosoluble body structure comprising a polyelectrolyte and a counterion and the methods of making and using the same.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: March 24, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Syed F. A. Hossainy, Mikael O. Trollsas, Lothar W. Kleiner
  • Patent number: 8987340
    Abstract: The invention relates to compositions suitable for the delivery and/or stabilization of biologically active substances. The compositions comprise a sublimable matrix material and the biologically active agent to be delivered. The compositions can be used as drug delivery systems to treat a wide variety of diseases or as systems for the protection and stabilization of such substances. Also disclosed are methods for preparing compositions of the present invention.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: March 24, 2015
    Assignee: Oakwood Laboratories, LLC
    Inventor: Richard Maskiewicz
  • Patent number: 8986738
    Abstract: A medical aid for the direct transport of at least one drug into lung regions of a patient, wherein provided as the carrier for at least one active substance is at least one semifluorinated alkane in which the at least one active substance is purely physically dissolved in a homogeneous phase.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: March 24, 2015
    Assignee: NOVALIQ GmbH
    Inventor: Hasso Meinert
  • Publication number: 20150079077
    Abstract: The present disclosure provides inter alia compositions that comprise therapeutic agents (e.g., live attenuated viral antigens, therapeutic proteins, etc.) and a lipid component. The lipid component may comprise or consist of different types of lipid or lipids as described herein. In some embodiments the therapeutic agents are thermolabile. The present disclosure also provides methods for preparing compositions, including the aforementioned compositions (e.g., melt methods and spray injection methods among others).
    Type: Application
    Filed: January 25, 2013
    Publication date: March 19, 2015
    Inventors: Marc J. Kirchmeier, David E. Anderson
  • Publication number: 20150080480
    Abstract: A method of producing a glycerin derivative-modified silicone or a composition comprising the same, including a process that treats the glycerin derivative-modified silicone or the composition comprising the same with one or more type of acidic inorganic salt, which is solid at 25° C. and water soluble, and which is such that a pH at 25° C. of an aqueous solution prepared by dissolving 50 g of the acidic inorganic salt in 1 L of ion exchanged water is 4 or lower; and an external use preparation, cosmetic composition, or raw materials thereof that contain the low odor glycerin derivative-modified silicone obtained by the production method.
    Type: Application
    Filed: December 26, 2012
    Publication date: March 19, 2015
    Inventors: Seiki Tamura, Tatsuo Souda, Seiji Hori
  • Patent number: 8980290
    Abstract: The present invention relates generally to compositions or formulations for transdermal or transmucosal administration of anticholinergic agents such as oxybutynin. The invention utilizes a novel delivery vehicle and is a substantially malodorous-free and irritation free transdermal formulation which is substantially free of long chain fatty alcohols, long-chain fatty acids, and long-chain fatty esters. A method is disclosed for treating a subject for urinary incontinence with these formulations while reducing the incidences of peak concentrations of drug and undesirable side effects associated with oral anticholinergics.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: March 17, 2015
    Assignee: Antares Pharma IPL AG
    Inventors: Dario Norberto R. Carrara, Arnaud Grenier
  • Patent number: 8980230
    Abstract: The present invention is directed towards a process for making oral compositions comprising gel networks. The gel networks are formed from a fatty amphiphile dispersion and swelling surfactant. The fatty amphiphile dispersion comprises one or more fatty amphiphiles, one or more dispersing surfactants, and one or more solvents. A gel network is formed when the fatty amphiphile dispersion is combined with the swelling surfactant. A method of preparing the fatty amphiphile dispersion and oral composition is included.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 17, 2015
    Assignee: The Procter & Gamble Company
    Inventors: Michael Jude LeBlanc, George Endel Deckner
  • Patent number: 8968775
    Abstract: Provided are pharmaceutical carriers based on oil-in-water microemulsions and methods of making same. Also provided are pharmaceutical compositions comprising a carrier of the invention and a lipophilic active pharmaceutical ingredient (API), as well as methods for making same. The pharmaceutical compositions are particularly suitable for use in formulating lipophilic APIs for topical administration to the eye. Specifically included are pharmaceutical compositions comprising fenofibrate or fenofibric acid as API. Also provided is a method of treating a disease of the posterior segment of the eye. Also provided is a pharmaceutical composition comprising a compound represented by formulated for topical administration to the eye.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 3, 2015
    Assignee: EyeCRO, LLC
    Inventors: Ronald A. Wassel, Fadee G. Mondalek, Rafal A. Farjo, Alexander B. Quiambao, Didier J. Nuño
  • Patent number: 8968769
    Abstract: The present invention features an orally disintegrating dosage form including from about 5% to about 40%, by weight, of at least one hydrated salt and a pharmaceutically active agent, wherein the at least one hydrated salt has a dehydration temperature of from about 20 to about 120 ° C.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: March 3, 2015
    Assignee: McNeil-PPC, Inc.
    Inventors: Frank Bunick, Joseph Luber
  • Publication number: 20150050323
    Abstract: Disclosed herein are inventive stable homogenized biomass hetero-colloids, their production and uses. Such biomass hetero-colloids comprise biomass derived solid particle colloid matter and at least 15% (w/w) biomass derived soluble colloid matter. The novel biomass hetero-colloids provide an inventive approach for the application of biologically active compounds. Bio-actives are made available in an innovative form involving low intervention processing and enhancing the biological availability.
    Type: Application
    Filed: April 19, 2013
    Publication date: February 19, 2015
    Inventor: Othmar KAEPPELI
  • Patent number: 8957116
    Abstract: To provide a solution for forming a double eyelid which enables extremely easy formation of a natural and ideal double eyelid without giving a displeased feeling or an uncomfortable feeling to a user, and a method for forming a double eyelid using the solution for forming a double eyelid. A solution for forming a double eyelid 1 according to the present invention is formed by dissolving, into a solvent having volatility, a fibrous material which forms a film 1a onto a skin 5a of an eyelid 5 and shrinks with vaporization of the solvent. By applying the solution 1, in a successive-curve form, over an imaginary line I forming a fold 5d of a double eyelid in the eyelid 5 onto which a user want to make a fold and vaporizing the solvent so as to shrink the film 1a, successive concaved groove-like constricted part 5c is formed on the imaginary line I and the fold 5d of a double eyelid along the constricted part 5c is formed.
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: February 17, 2015
    Inventors: Naoko Iwagaki, Masayuki Kamagata, Jirou Taniyama
  • Patent number: 8956598
    Abstract: The invention relates to hydrocarbon mixtures containing the 14C isotope, use thereof and cosmetic and/or pharmaceutical preparations comprising hydrocarbon mixtures containing the 14C isotope.
    Type: Grant
    Filed: June 12, 2008
    Date of Patent: February 17, 2015
    Assignee: Cognis IP Management GmbH
    Inventors: Bettina Jackwerth, Markus Dierker, Rolf Kawa, Stefanie Maurer
  • Publication number: 20150045455
    Abstract: Methods for preparing a PEG composition by co-precipitation of two or more components to produce a substantially homogenous powder. According to some embodiments, the two or more components are at least and partially soluble in a solvent, and at least one component is a functionalized PEG. Contacting the at least two component with the solvent at least partially dissolves the components which are then co-precipitated. The resulting product is substantially homogenous, unlike product made by other methods. The PEG composition may be co-precipitated with additional compounds, such as a colorant like indocyanine green.
    Type: Application
    Filed: March 15, 2013
    Publication date: February 12, 2015
    Applicant: NEOMEND, INC.
    Inventors: Tina Lanette Mcarthur, Tracy Hutchison, Jon Mckannan, Charles Vaughn Cassingham
  • Patent number: 8951431
    Abstract: Provided are azeotropic and azeotrope-like compositions of 1,2,3,3,3-pentafluoropropene (HFO-1225ye) and water. Such azeotropic and azeotrope-like compositions are useful in isolating 1,2,3,3,3-pentafluoropropene from impurities during production. Azeotropes of the instant invention are similarly useful in final compositions or manufacturing final compositions, such as blowing agent, propellants, refrigerants, diluents for gaseous sterilization and the like.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: February 10, 2015
    Assignee: E I du Pont de Nemours and Company
    Inventors: Ryan Hulse, Haluk Kopkalli, Hang T. Pham
  • Publication number: 20150037394
    Abstract: Mixtures of C1-12 compounds comprising at least one -Alk-O— group with thermogenic formulations, such as those comprising supercooled solutions of salts, are capable of substantial enhancement of transdermal drug delivery.
    Type: Application
    Filed: June 22, 2012
    Publication date: February 5, 2015
    Inventors: Daniel Guy Wood, Stuart Allen Jones, Marc Barry Brown
  • Publication number: 20150030684
    Abstract: An irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers is described. Also, methods for treating a bone having a bone gap or a bone defect with the composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers are also provided. Also, kits including the irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material and a mixture of non-random poly(oxyalkylene) block copolymers are described.
    Type: Application
    Filed: October 13, 2014
    Publication date: January 29, 2015
    Inventors: Gregory J. Pomrink, Cecilia A. Cao, Zehra Tosun, David M. Gaisser
  • Publication number: 20150024022
    Abstract: The present disclosure relates to a hydrogel composition and methods of using the same. The hydrogel composition may include precursors that react with each other upon contact as well as precursors that react upon contact with an initiator. In embodiments, the resulting hydrogels may have varying levels of crosslinking with both denser and less dense regions.
    Type: Application
    Filed: October 7, 2014
    Publication date: January 22, 2015
    Inventors: Steven Bennett, Nathaniel Mast, Kevin Lavigne, Walter Skalla, Saumya Banerjee, Timothy Sargeant, Joshua Stopek
  • Publication number: 20150025020
    Abstract: The present invention relates to a self-preserved oil dispersion. Especially, the present invention relates to a self-preserved oil dispersion including a dispersed oil phase, an aqueous phase and at least one surfactant, wherein said oil dispersion comprises boric acid in an amount ranging from 0.005% to 0.075% in weight of the total weight of the oil dispersion, said amount of boric acid being a preservative effective amount so that the oil dispersion has a preservative activity.
    Type: Application
    Filed: February 22, 2013
    Publication date: January 22, 2015
    Inventors: Jean-Sébastien Garrigue, Frédéric Lallemand, Betty Philips
  • Patent number: 8937033
    Abstract: The present invention relates to the use of phosphated 2-propylheptanol, phosphated 2-proyplheptanol alkoxylate and/or mixtures thereof in agricultural formulations. The invention also relates to agricultural formulations comprising the aforementioned adjuvants, and to methods of treating a plant with the agricultural formulations of the invention.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: January 20, 2015
    Assignee: Akzo Nobel N.V.
    Inventor: Mark Alexander