Abstract: The invention relates to N-cyanomethylated chitosans of formula (1) and to the hydrolysates thereof of formula (2), as well as to processes for the preparation of these compounds. The cyanomethylated chitosans, in particular the hydrolysates corresponding to formula (2), find versatile utility as separating membranes, complexing agents, encrustation inhibitors, stabilisers for bleaching liquors, moisture retainers in cosmetic compositions, thickeners and repellents.

Abstract: The present invention is directed to compositions, particularly cosmetic compositions, in which the oil is thickened using at least one copolymer which has a hydrophobic functionality sufficient to provide at least partial solubility and optionally stability in oil and a hydrophilic functionality sufficient to provide thickening of the oil. Use of such copolymers as thickening agents are advantageous in that they are soluble and stable in the oil phase. Further, sufficient thickening may be accomplished using very low amounts of these copolymers without the use of additional polymeric thickeners.

Abstract: The present invention deals with the application of certain novel esters which are prepared by the reaction of a guerbet alcohol and meadowfoam fatty, methyl ester or triglyceride in personal care applications. These materials are useful as cosmetic ingredients where outstanding liquidity, resistance to oxidation, and minimal taste and odor variation are required. This combination of properties make these compounds excellent candidates as additives to personal care products like skin care oils and lipsticks.

Abstract: The invention encompasses topical sunblock formulae for shielding skin from ultraviolet radiation, and a composite sunblocking component thereof. The sunblocking component of the formula includes an effective amount of a plurality of particles having diameters in the range of about 0.01-100 microns, each particle including a matrix and a UV-attenuating compound incorporated into the matrix. The composite sunblocking component may include a particle that is colored or transparent, depending upon the matrix, UV-attenuating compound and the particle size. The sunblocking component is dispersible in water and thus in water-based dermatological carriers. The formula includes these particles dispersed within a dermatologically acceptable liquid carrier in at least an amount sufficient to shield substantially all of the skin over which the formula is applied from hazardous effects of ultraviolet radiation.

Abstract: Fatty acid amides in combination with azoles and either retinol or retinyl ester resulted in a synergistic enhancement in keratinocyte proliferation and synergistic inhibition of keratinocyte differentiation. The effects of the retinol or retinyl esters in combination with fatty acid amides and azoles were analogous to treatment with retinoic acid.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin mucic acid or mucolactone.

Abstract: Topical formulations comprising an anti-irritant amount of aqueous-soluble strontium (Sr.sup.2+) cation, and methods for using the same to inhibit skin irritation, are disclosed.

Abstract: This disclosure introduces the use of an isophorone diisocyanate urethane polymer of naturally occurring castor oil as an active ingredient for skin and personal care compositions and products.

Abstract: Preventive as well as therapeutic treatment to alleviate cosmetic conditions and symptoms of dermatologic disorders with amphoteric compositions containing alpha hydroxyacids, alpha ketoacids, related compounds or polymeric forms of hydroxyacids is disclosed. The cosmetic conditions and the dermatologic disorders in which the amphoteric compositions and the polymeric compounds may be useful include dry skin, dandruff, ache, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, warts, blemished skin, hyperpigmented skin, kyperkeratotic skin, inflammatory dermatoses, skin changes associated with aging, and skin requiring cleansers.

Abstract: Melinamide in combination with either retinol or retinyl ester resulted in a synergistic enhancement in keratinocyte proliferation. The effects of the retinol or retinyl esters in combination with fatty acid amides were analogous to treatment with retinoic acid.

Abstract: The present invention discloses ceramide 3 derivatives based on monounsaturated fatty acids. A preferred compound is N-oleoylphytosphingosine (Ceramide IIIB). A method for preparing these compounds is also disclosed. The solubility of these compounds is higher than the solubility of the corresponding saturated ceramide 3 derivatives, whereas their stability is comparable to saturated ceramide 3 stabilities. In addition, a method is described for maintaining the water permeability characteristics of the skin by topical application of a formulation containing a monounsaturated ceramide 3 derivative.

Abstract: Composition and method for enhancing therapeutic effects of topically applied agents are disclosed. The cosmetic or therapeutic composition may include one or more of cosmetic or pharmaceutical agents present in a total amount of from 0.01 to 40 percent and one or more of hydroxycarboxylic acids or related compounds present in a total amount of from 0.01 to 99 percent by weight of the total composition. The cosmetic and pharmaceutical agents may include but not limited to age spots, wrinkles and keratoses removing agents; vitamins; aloes; sun screens; tanning, depigmenting and shampooing agents; antiyeasts; antifungal, antibacterial and antiviral agents; topical bronchial dilators and topical cardiovascular agents; hormonal agents; vasodilators; retinoids and other dermatological agents. The hydroxycarboxylic acids and related compounds include organic alpha and beta hydroxycarboxylic acids, alpha and beta ketocarboxylic acids and salts thereof.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: Cosmetic compositions containing water having a mineralization of at least 400 mg/l and an active agent having an irritant side effect exhibit a reduced irritant effect; the water is especially a thermal spring water and/or mineral water and the active agent is especially a keratolytic agent of the salicylic acid derivative type.

Abstract: An external skin treatment composition comprising (i) vitamin A and (ii) at least one skin roughening improvement aid selected from the group consisting of (a) polyoxyalkylene modified organopolysiloxanes, (b) sugars, and (c) anti-inflammatory agents.

Abstract: Alpha hydroxyacid esters and related compounds on topical application induced increased skin thickness due to new biosyntheses of dermal components including glycosaminoglycans, proteoglycans, collagen and elastin. Such dermal effects are desirable and beneficial for topical use and treatment of aging related integumental changes including age spots, skin lines, wrinkles, photoaging and aging skin.

Abstract: Methods for improved topical delivery of lactic acid comprising forming a topically acceptable composition by admixing lactic acid and an amphoteric or pseudoamphoteric agent, and applying said topically acceptable composition to the skin.

Abstract: Methods for improved topical delivery of an alpha hydroxyacid, alpha ketoacid or related compound.

Abstract: Cationic dispersion containing at least 1) one natural or synthetic ceramide or glycoceramide or a mixture of natural or synthetic ceramides and/or glycoceramides of formula (I) where R.sub.1 denotes C.sub.14 -C.sub.30 alkyl, R.sub.2 denotes hydrogen, (glycosyl).sub.n, (galactosyl).sub.m or sulfogalactosyl, n having the value 1 to 4 and m having the value 1 to 8, R.sub.3 denotes a C.sub.15 -C.sub.26 hydrocarbon radical or a C.sub.15 -C.sub.26 .alpha.-hydroxyalkyl radical in the case of the natural ceramides and/or glycoceramides; 2) a compound of formula (II) where X is an anion and a) R.sub.4, R.sub.5 and R.sub.6 denote C.sub.1 -C.sub.4 alkyl and R.sub.7 denotes C.sub.22 alkyl, or b) R.sub.4 and R.sub.5 denote C.sub.1 -C.sub.4 alkyl and: (i) R.sub.6 and R.sub.7 denote C.sub.20 -C.sub.22 alkyl; or (ii) R.sub.6 denotes C.sub.22 alkyl and R.sub.7 denotes benzyl; or c) R.sub.4 denotes C.sub.1 -C.sub.4 alkyl, R.sub.5 denotes (alkyl and/or alkenyl)amidoethyl and R.sub.6 and R.sub.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin mandelic acid.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin gluconic acid or gluconolactone.

Abstract: The liquid of the present invention can provide good cleansing, lather and good sensory feel and yet surprisingly provide a lipid moisturizing benefit via deposition of the lipid on the skin of the user. The liquid composition is stable and on a macro scale is homogeneous. The dual cleansing and lipid moisturizing liquid composition of this invention comprises: (1) about 5 parts to about 30 parts of a lipid skin moisturizing agent; (2) about 1 to about 15 parts of an ethylene glycol fatty acid ester; (3) from about 0.05 parts to about 3 parts of a selected water dispersible gel forming polymer (4) from about 5 parts to about 30 parts of a lathering synthetic surfactant, and; (5) water, and wherein said synthetic surfactant and any soap has a combined CMC equilibrium surface tension value of from 15 to 50, and wherein said lathering skin cleansing liquid composition has a Lipid Deposition Value (LDV) of from about 5 to about 1000 .mu.g of lipid per sq. cm of skin.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin citric acid.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin lactic acid.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin glucuronic acid or glucuronolactone.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin pantoic acid or pantolactone.

Abstract: A formulation containing tretinoin, a gelling agent, proteinaceous material, and water is provided for the uniform topical application of tretinoin. The water-based formulation is oil- and fat-free, alcohol-free, and rich in proteinaceous material. The formulation is stable over time and is comedogenic and less irritating and drying to the skin.

Abstract: A method for visibly reducing a facial wrinkle by topically applying to the wrinkle gulonic acid or a topically effective salt thereof, or gulonolactone.

Abstract: Composition and method for enhancing therapeutic effects of topically applied agents are disclosed. The cosmetic or therapeutic composition may include one or more of cosmetic or pharmaceutical agents present in a total amount of from 0.01 to 40 percent and one or more of hydroxycarboxylic acids or related compounds present in a total amount of from 0.01 to 99 percent by weight of the total composition. The cosmetic and pharmaceutical agents may include but not limited to age spots, wrinkles and keratoses removing agents; vitamins; aloes; sun screens; tanning, depigmenting and shampooing agents; antiyeasts; antifungal, antibacterial and antiviral agents; topical bronchial dilators and topical cardiovascular agents; hormonal agents; vasodilators; retinoids and other dermatological agents. The hydroxycarboxylic acids and related compounds include organic alpha and beta hydroxycarboxylic acids, alpha and beta ketocarboxylic acids and salts thereof.

Abstract: The invention relates to preparations for the improved release of oxygen into the skin and to the use of same as cosmetics/dermatics. The preparations according to this invention contain, as the essential component, fluorocarbon emulsions consisting of nonionic emulsifiers and an oxygen-loaded fluorocarbon or fluorocarbon mixture, the fluorocarbon content being in the range from 0.05 to 100% by weight/volume. They are prepared by emulsifying the corresponding components and incorporating the resulting emulsion in known carriers for, for example, ointments, creams, lotions, waters, alcoholic extracts, pastes, powders, gels, tinctures or masks.

Abstract: The ceramides according to the invention are compounds corresponding to the formula: ##STR1## in which: R.sub.1 is a C.sub.11 to C.sub.21 alkyl or alkenyl radical;R.sub.2 is a linear or branched C.sub.1 to C.sub.29 hydroxyalkyl radical or a C.sub.7 to C.sub.29 hydroxyaralkyl radical, these compounds being in the form of a racemic mixture of the erythro and threo diastereoisomers for the aminodiol part ##STR2## in erythro:threo ratios of from 85:15 to 20:80. Application to cosmetic and dermopharmaceutical compositions.

Abstract: The present invention are anhydrous after shave lotions comprising a perfume, an alcohol, and a low viscosity silicone fluid. Said compositions have less stinging and burning than compositions known in the art. Furthermore, said compositions are economical and have good skin feel characteristics.

Abstract: The invention relates to the use of acylated sugar monoacid amides in cosmetic preparations corresponding to formula I: ##STR1##

Abstract: A method for strengthening of the mechanical and/or cosmetic properties of keratinous superficial body growths such as the hair, the eyelashes and the nails, by applying certain bioflavonoids, in particular citrus bioflavonoids, as treatment agents to the keratinous superficial body growths. Also, stable compositions containing bioflavonoids and a method for protecting the keratin of superficial body growths from damage by environmental agents.

Abstract: A system for moisturizing the skin and decreasing established acne is presented. The system consist of a therapeutic preparation comprised of bananas, orange juice, and coconut milk. An alternative procedure consist of the use of a conventional cleanser, toner, facial scrub, and moisturizer. These preparations provide moisturizing benefits, performs a skin sloughing treatment, and alleviates many undesirable skin conditions, including acne. The preparation is used with a facial mask which seals the therapeutic skin treatment on the skin and protects the skin from bacteria and contaminants.

Abstract: A skin cream composition according to the present invention provides significant retexturization of the skin, producing significantly improved smoothness, as well as significantly minimizing age spots and improving color of the skin, together with increasing the firmness and moisture content of the skin. The composition also reduces the extent of sebum and/or oil on the skin. The composition can comprise: water, and emulsified and dispersed in the water: (1) sodium lactate; (2) a long-chain fatty acid ester of ascorbic acid; (3) a short-chain carboxylic acid ester of tocopherol; (4) witch hazel; and (5) horsetail extract. The sodium lactate, the ascorbic acid ester, the tocopherol ester, the witch hazel, and the horsetail extract are each present in a quantity sufficient to increase the smoothness and/or firmness and to diminish the oiliness of skin to which the composition is applied.

Abstract: A preparation for external application to the skin which comprises disodium adenosine triphosphate and tranexamic acid for prevention of skin roughening and skin improvement. The preparation further contains ginseng extract.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin ribonic acid or ribonolactone.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin quinic acid or quinolactone.

Abstract: The present invention deals with the certain novel esters which are prepared by the reaction of an alpha methyl alcohol and a fatty acid. These materials are useful as conditioning agents for skin.

Abstract: A dermatological or cosmetic composition for skin care containing 0.01 to 30% by weight of at least one ceramide and 1 to 15% by weight of linoleic acid useful for restoring the barrier function of the stratum corneum of dry or very dry skin.

Abstract: The invention relates to personal product compositions containing heteroatom containing alkyl aldonamide compounds and skin conditioning agent. Unexpectedly, applicants have found that when these heteroatom containing alkyl aldonamides are used, benefits such as enhanced stability and/or enhanced viscosity are obtained relative to the use of other known thickeners or non-heteroatom containing aldonamides.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin gulonic acid or gulonolactone.

Abstract: A cosmetic component is produced by dispersing in water a water-soluble fiber composed of about 4 to 6 weight percent beta glucan, about 1 to 5 weight percent fat, about 80 to 94 weight percent carbohydrates and less than 8 weight percent protein. The fiber composition forms a dispersion (e.g., a first paste or gel) with the hot water, which is mixed for about 1 to 5 minutes. Following mixing, the dispersion is cooled and then combined with one or more stable cosmetic components to form a cosmetic product. One novel cosmetic component useful with the invention is composed of: (a) about 4.0 to about 8.0 percent water by weight; (b) about 4.5 to about 5.5 percent beta-glucan by weight; (c) less than 8.0 percent protein by weight; (d) about 2.0 to 3.0 percent ash by weight; (e) about 1.0 to about 5.0 percent fat by weight; and (f) about 80 to about 94 percent carbohydrate by weight.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin glycolic acid.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy to mammalian skin comprising treating the skin with a safe and effective amount of salicylic add and/or additional active component.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin galactonic acid or galactonolactone.

Abstract: Moisturizing composition for the simultaneous treatment of the surface layers and deep layers of the skin, and use thereof. The composition of the invention comprises a first dispersion of lipid vesicles which are capable of penetrating into the deep layers of the skin and which contain at least one active agent selected from the group consisting of polyols, sugars, proteins, vitamins and the derivatives thereof, ceramides, essential fatty acids, and sterols, for treating these deep layers, and a second dispersion of lipid vesicles which are capable of penetrating into the surface layers of the skin and which contain at least one active agent selected from the group consisting of polyols, nitrogen-containing carboxylic acid derivatives, keratolytic agents, inorganic salts and lipoamino acids, for treating these surface layers.

Abstract: A cosmetic composition containing triglyceride oleate and yeast extract and further, if desired, an L-cysteine hydrochloride as components for proliferating indigenous bacteria on the skin.