Seborrhea Patents (Class 514/864)
  • Patent number: 8951775
    Abstract: The present invention relates to the cosmetic use of an effective amount of at least one probiotic microorganism and/or a fraction thereof and/or a metabolite thereof, as an agent for treating and/or preventing oily skin or skin with an oily tendency and the associated skin disorders.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: February 10, 2015
    Assignees: L'Oreal, Nestec SA
    Inventors: Isabelle Castiel, Audrey Gueniche
  • Patent number: 8609718
    Abstract: Disclosed is a novel use of phytosphingosine. More particularly, disclosed are a composition for preventing or treating hyper-proliferative skin diseases comprising pachastrissamine as an active ingredient, a use of pachastrissamine or a pharmaceutically acceptable salt thereof for preparing a preventing/therapeutic agent of hyper-proliferative skin diseases, and a method for treating hyper-proliferative skin diseases administering an effective amount of pachastrissamine or a pharmaceutically acceptable salt thereof to a subject in need thereof. The pachastrissamine inhibits the degradation of FoxO3a protein and increases the expression of FoxO3a protein. Thus, the inventive pharmaceutical composition has a preventing of treating effect on hyper-proliferative diseases by inducing apoptosis of hyper-proliferative cells and inhibiting the cell cycle.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: December 17, 2013
    Assignee: Catholic University Industry Academy Cooperation Foundation
    Inventors: Dong Heon Shin, Tae Yoon Kim
  • Patent number: 8591876
    Abstract: Provided herein are methods of using gaseous nitric oxide and/or at least one nitric oxide source to or decrease sebum production in the skin of a subject. In some embodiments, the nitric oxide source includes small molecule and/or macromolecular NO-releasing compounds.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: November 26, 2013
    Assignee: Novan, Inc.
    Inventors: Susanne Bauman, Nathan A. Stasko
  • Patent number: 8586066
    Abstract: A topical, foamable composition is provided that includes at least one antifungal agent that is able to penetrate the upper layers of skin and is retained in or on an area to be treated for a prolonged period of time, and that has a residual non-volatile component content less than 25%. In addition, a method of treating fungal diseases including jock itch, tinea, dandruff and sebborheic dermatitis is provided, and includes applying to the affected area of patient requiring such treatment an antifungal composition.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: November 19, 2013
    Assignee: Delcor Asset Corporation
    Inventors: Greg Davey, Albert Zorko Abram
  • Patent number: 8529970
    Abstract: Materials with high levels of unsaponifiable matter, such as extracts from plants, produce hydrolysates with unique properties. Properties that are sought in traditional saponification of natural oils are a result of low levels of unsaponifiables. These properties include high levels of aqueous surfactant activity, water-solubility or ready water-dispersability, activity as foaming agents, and the like. An objective of traditional saponification processes is to increase the water-solubility and surfactant activity of naturally occurring materials. It has been found that the application of a hydrolysis process to materials, particularly materials with a high level of unsaponifiables (e.g., at least 6 weight percent of the material), produces a product with properties significantly different from those products resulting from the conventional saponification of materials with less than 6 weight percent of unsaponifiables.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: September 10, 2013
    Assignee: International Flora Technologies, Ltd.
    Inventors: James H. Brown, Lee Roy Copeland, Robert Kleiman, Melanie K. Cummings, Sambasivarao Koritala
  • Patent number: 8512718
    Abstract: A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepared by mixing 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, by weight, wherein at least one of them has therapeutic or cosmetic benefits, in the presence or absence of a biologically active substance.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: August 20, 2013
    Assignee: Foamix Ltd.
    Inventors: Meir Eini, Dov Tamarkin
  • Patent number: 8501202
    Abstract: A topical composition for the treatment of mammalian skin dermatoses comprising a sulfacetamide or a derivative thereof and at least 1 sunscreen wherein the sunscreen is present in a sufficient amount to produce a sun protection factor of about 1.6 to about 20.6. Also provided is a method of treating mammalian dermatoses by administering a topical composition comprising a sulfacetamide or a derivative thereof and at least 1 sunscreen wherein the sunscreen is present in a sufficient amount to produce a sun protection factor of about 1.6 to about 20.6.
    Type: Grant
    Filed: January 26, 2006
    Date of Patent: August 6, 2013
    Assignee: Aqua Pharmaceuticals, LLC
    Inventor: Charles W. Stiefel
  • Patent number: 8465763
    Abstract: The present invention relates to the use of 3?-hydroxychlormadinone acetate (17?-acetoxychloropregna-4,6-dien-3?-ol-20-one) and/or 3?-hydroxychlormadinone acetate (17?-acetoxychloropregna-4,6-dien-3?-ol-20-one) for producing a medicament for treating skin, preferably human skin by means of topical application, and to a pharmaceutical or cosmetic composition containing 3?-hydroxychlormadinone acetate and/or 3?-hydroxychlormadinone acetate.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: June 18, 2013
    Assignee: Richter Gedeon Nyrt.
    Inventors: Georg Schramm, Christa Kneip
  • Patent number: 8287846
    Abstract: The present invention relates to odour improved dermatological or cosmetic preparations comprising N-acetylcysteine and a polyol system containing one or more polyols as masking odour agents. The emulsions of the present invention are useful in the treatment of dermatological disorders or cosmetic skin conditions.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: October 16, 2012
    Assignee: ZAMBON S.p.A.
    Inventors: Luca Rampoldi, Alberto Moretto, Alessandro Grassano
  • Patent number: 8227490
    Abstract: Compounds of the formula (I) are disclosed and are suitable for the treatment of seborrheic dermatitis.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: July 24, 2012
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Manfred Bohn, Karl Theodor Kraemer, Astrid Markus
  • Patent number: 8026238
    Abstract: A topical, foamable composition is provided that includes at least one antifungal agent that is able to penetrate the upper layers of skin and is retained in or on an area to be treated for a prolonged period of time, and that has a residual non-volatile component content of less than 25%. In addition, a method of treating fungal diseases including jock itch, tinea, dandruff and sebborheic dermatitis is provided, and includes applying to the affected area of a patient requiring such treatment an antifungal composition.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: September 27, 2011
    Assignee: Stiefel Research Australia, Pty Ltd
    Inventors: Greg Davey, Albert Zorko Abram
  • Patent number: 7981909
    Abstract: Compounds of the formula (I) are disclosed and are suitable for the treatment of seborrheic dermatitis.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: July 19, 2011
    Assignee: Medicis Pharmaceutical Corporation
    Inventors: Manfred Bohn, Karl Theodor Kraemer, Astrid Markus
  • Patent number: 7682623
    Abstract: A pharmaceutical or cosmetic carrier or composition for topical application characterized by rheological properties which render the carrier or composition semi-solid at rest and a liquid upon application of shear forces thereto. The composition or carrier are prepared by mixing 1-25 percent of a solidifying agent and 75-99 percent of a hydrophobic solvent, by weight, wherein at least one of them has therapeutic or cosmetic benefits, in the presence or absence of a biologically active substance.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: March 23, 2010
    Assignee: Foamix Ltd.
    Inventors: Meir Eini, Dov Tamarkin
  • Patent number: 7553835
    Abstract: The subject matter relates to a topical, foamable composition including at least one antifungal agent, said composition characterised in that said at least one antifungal agent is able to penetrate the upper layers of skin and is retained in or on an area to be treated for a prolonged period of time, and in that it has a residual non-volatile component content of less than 25%. The subject matter furthermore relates to a method of treating fungal diseases including jock itch, tinea, dandruff and sebborheic dermatitis by applying to the affected area of a patient requiring such treatment the antifungal composition.
    Type: Grant
    Filed: October 19, 1998
    Date of Patent: June 30, 2009
    Assignee: Stiefel Research Australia Pty Ltd
    Inventors: Greg Davey, Albert Zorko Abram
  • Patent number: 7357938
    Abstract: A method for treating rosacea in a patient comprising administering to a patient suffering from rosacea a first topical composition comprising at least one sulfacetamide or a derivative thereof and at least one sunscreen, wherein the administration of said first composition provides a more effective treatment of said rosacea in comparison to treatment of rosacea achieved by administration of a second topical composition comprising metronidazole.
    Type: Grant
    Filed: September 10, 2004
    Date of Patent: April 15, 2008
    Assignee: Stiefel Laboratories, Inc.
    Inventor: Charles W. Stiefel
  • Patent number: 7312196
    Abstract: The present invention is concerned with a pharmaceutical formulation comprising an amylin agonist and optionally a buffer, a tonicifier or stabilizer, and a preservative in a container, for example, a vial, prefilled cartridge, prefilled syringe or disposable pen. This formulation may be in liquid, gel, solid or powdered form for delivery, for example, via nasal, pulmonary, oral, sublingual, buccal, transdermal, or parenteral routes. Formulation with biocompatible polymers and release modifiers, such as sugars, can facilitate controlled release after injection, minimizing the number of administrations to a patient. These formulations maintain stability upon storage under refrigerated or room temperature conditions. Such formulations can be further combined with insulin for administration to a patient.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: December 25, 2007
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: James L'Italien, Gregg Stetsko
  • Patent number: 7252831
    Abstract: This invention relates to improved compositions and methods for preventing or inhibiting the development of ingrown hairs or razor bumps in skin subjected to hair removal techniques by applying compositions containing sebum reduction agents; keratolytic agents and anti-inflammatory agents.
    Type: Grant
    Filed: June 12, 2006
    Date of Patent: August 7, 2007
    Assignee: J&J Consumer Companies, Inc.
    Inventors: Alain V. Khaiat, Anna Gomes, Vaishali Bhide, Catherine Salerno, Victoria Dole
  • Patent number: 7201931
    Abstract: Pharmaceutical and/or cosmetic compositions for the treatment and the prevention of scalp disorders, containing as active components extracts of Serenoa repens and of Vitis vinifera.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: April 10, 2007
    Assignee: Indena S.p.A.
    Inventor: Francesco Di Pierro
  • Patent number: 7186754
    Abstract: The present invention relates to the use of creatine compounds such as, for example, creatine, creatine phosphate or analogs of creatine, such as creatine-pyruvate, creatine-ascorbate, cyclocreatine, 3 guanidinopropionic acid, guanidinoacetate, homocyclocreatine, guanidino benzoates as energy generating systems and antioxidants for preservation of skin against adverse aging effects and damage secondary to insults such as harmful sun radiations, stress and fatigue. The creatine compounds which can be used in the present method include (1) creatine, creatine phosphate and analogs of these compounds which can act as substrates or substrate analogs for creatine kinase; (2) molecules that mimic the biological activity of creatine (3) molecules that modulate the creatine kinase system.
    Type: Grant
    Filed: March 23, 2005
    Date of Patent: March 6, 2007
    Assignee: Avicena Group, Inc.
    Inventor: Rima Kaddurah-Daouk
  • Patent number: 7094431
    Abstract: This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or wound healing composition alone. In one embodiment, the wound healing composition comprises (a) zinc oxide; (b) calcium channel blocker, and (c) fat-soluble vitamins admixed with antibacterial and antifungal agents. The therapeutic antibacterial/antifungal-wound healing compositions may be utilized in a wide variety of pharmaceutical products and administered orally or topically.
    Type: Grant
    Filed: September 30, 2003
    Date of Patent: August 22, 2006
    Inventor: Mickey L. Peshoff
  • Patent number: 7022332
    Abstract: The present invention provides improved sulfacetamide and sulfur formulations including sunscreens for the treatment of rosacea.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: April 4, 2006
    Assignee: Stiefel Laboratories, Inc.
    Inventor: Charles W. Stiefel
  • Patent number: 6979468
    Abstract: A method and composition for the treatment of acne vulgaris, acne rosacea, and other inflammatory skin conditions comprises the oral administration of a composition comprising a dose of nicotinamide delivered at levels substantially in excess of normal dietary levels, the nicotinamide being delivered in combination with zinc. The composition may also include quantities of copper and folic acid. In a most preferred embodiment, the nicotinamide and copper each are present in immediate release formats, while the zinc is present in a sustained release format.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: December 27, 2005
    Assignee: Sirius Laboratories
    Inventor: Frank Pollard
  • Patent number: 6946153
    Abstract: A method of treating a patient suffering a disease associated with Trichophyton mentagrophytes or Pityrosporum ovale by applying topically an anti-fungal pharmaceutical composition which is prepared from Zingiber officinale, includes the following steps: preparing a crude liquid from rhizomes of ginger by extraction with an organic solvent or supercritical CO2, or by distillation with steam; introducing the crude liquid to a reverse phase chromatography column, and eluting the column with water, a first eluent and a second eluent having a polarity weaker than that of the first eluent but stronger than that of chloroform, so that a first eluate resulting from elution of the first eluent and a second eluate resulting from elution of the second eluent are obtained; removing the first eluent and the second eluent from the first eluate and the second eluate by evaporation, respectively, so that a first concentrated eluate and a second concentrated eluate are obtained as the potent extract.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: September 20, 2005
    Assignee: Medical and Pharmaceutical Industry Technology and Development Center
    Inventors: Tian-Shung Wu, Sheng-Chu Kuo, Che-Ming Teng, Feng-Nien Ko
  • Patent number: 6939568
    Abstract: The invention relates to the use of one or more antimicrobial metals, most preferably silver, preferably formed with atomic disorder, and preferably in a nanocrystalline form, for the treatment of inflammatory skin conditions. The nanocrystalline antimicrobial metal of choice may be used in the form of a nanocrystalline coating of one or more antimicrobial metals, a nanocrystalline powder of one or more antimicrobial metals, or a solution containing dissolved species from a nanocrystalline powder or coating of one or more antimicrobial metals.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: September 6, 2005
    Assignee: Nucryst Pharmaceuticals Corp.
    Inventors: Robert Edward Burrell, Hua Qing Yin
  • Patent number: 6867238
    Abstract: Compositions are provided for the topical treatment of cancer consisting of lotions, creams, sprays, suppositories or slow-release transdermal patches containing lipid-soluble, skin-penetrating organic selenium compounds in combination with inert carriers in therapeutically effective amounts of selenium compound. The selenium compounds are medium linear chain dialkyl diselenides and precursors such as alkyl selenols. Preferred compositions employ R—Se—Se—R compounds where R is from 6 to 8 carbon atoms, and most specifically di-n-hexyl diselenide. Commonly used carriers may be purified hydrocarbon fractions, oils, with or without added fat-soluble vitamins, water and emulsifying agents.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: March 15, 2005
    Inventor: Gerhard N. Schrauzer
  • Patent number: 6756060
    Abstract: Compositions and methods for treating wounds to significantly reduce the healing time, reduce the incidence of scar formation, improve the success of skin grafts, reduce the inflammatory response and providing anti-bacterial treatments to a patient in need thereof, that include small non-interlinked particles of bioactive glass or highly porous bioactive glass, are disclosed. Anti-bacterial solutions derived from bioactive glass, and methods of preparation and use thereof, are also disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with anti-bacterial agents and/or anti-inflammatory agents. The compositions can include an appropriate carrier for topical administration. Anti-bacterial properties can be imparted to implanted materials, such as prosthetic implants, sutures, stents, screws, plates, tubes, and the like, by incorporating small bioactive glass particles or porous bioactive glass into or onto the implanted materials.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: June 29, 2004
    Assignee: USBiomaterials Corp.
    Inventors: David C. Greenspan, Jon K. West, Sean Lee, James L. Meyers, Mason Diamond
  • Patent number: 6730703
    Abstract: The present invention provides a method of treating sebaceous gland disorders comprising administering to a patient in need of said treatment an effective amount of a compound named [(2,4,6-triisopropyl-phenyl)-acetyl]-sulfamic acid 2,6-diiso-propyl-phenyl ester or a pharmaceutically acceptable salt thereof. Particularly, methods of treating sebaceous gland disorders are provided wherein said disorders are selected from seborrhea, acnes, perioral dermatitis, rosacea, and corticosteroid-induced acneiform lesions. The present invention provides methods of treating acnes such as, for example, chloracne, ciliaris acne, cystic acne, keratosa acne, vulgaris acne, senile acne, and medicinal acne.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: May 4, 2004
    Assignee: Warner-Lambert Company
    Inventor: Reynold Homan
  • Patent number: 6703026
    Abstract: The present application relates to cosmetic compositions containing, in a cosmetically acceptable aqueous medium, at least one polyorganosiloxane and an acrylic terpolymer, as well as to the use of these compositions for treating keratinous material, in particular the skin or the hair. The acrylic terpolymer comprises: a) about 20 to 70% by weight of a carboxylic acid containing &agr;,&bgr;-monoethylenic unsaturation; b) about 20 to 80% by weight of a non-surfactant monomer containing monoethylenic unsaturation, which is different from a), and c) about 0.5 to 60% by weight of a nonionic urethane monomer which is the product of reaction of a monohydric nonionic surfactant with a monoisocyanate containing monoethylenic unsaturation. The polyorganosiloxane is preferably a non-volatile silicone.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: March 9, 2004
    Assignee: L'Oreal
    Inventor: Christine Dupuis
  • Patent number: 6696069
    Abstract: Cosmetic skin care methods and compositions containing phosphates and/or sulfates of branched alcohols and/or ethoxylates thereof. The inventive compositions provide control of sebum secretion from sebocytes, improved oil control and improved skin feel, prevent shine and stickiness, while also providing anti-aging benefits which results in reduced appearance of wrinkles and aged skin, improved skin color, treatment of photoaged skin, improvement in skin's radiance and clarity and finish, and an overall healthy and youthful appearance of the skin.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: February 24, 2004
    Assignee: Unilever Home & Personal Care USA, division of Conopco, Inc.
    Inventors: Bijan Steven Harichian, Laurence Boen, John Steven Bajor
  • Patent number: 6692773
    Abstract: The invention relates to the use of one or more noble metals selected from silver, gold, platinum, and palladium but most preferably silver, in a nanocrystalline form, for the treatment of a hyperproliferative skin disorder or disease such as psoriasis. Among the noble metals, silver is preferred for such treatment. The nanocrystalline noble metal of choice may be used in the form of a nanocrystalline coating of one or more noble metals, a nanocrystalline powder of one or more noble metals, or a solution containing dissolved species from a nanocrystalline powder or coating of one or more noble metals.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: February 17, 2004
    Assignee: Nucryst Pharmaceuticals Corp.
    Inventors: Robert Edward Burrell, John Barrymore Wright, Kan Lam
  • Patent number: 6692775
    Abstract: A gel formulation is combined with a bactericidal concentrate which is a liquid mixture of about 1000 parts by volume of ultra pure water having an electrical resistance of 16-26 megohms, total dissolved solids of less than 0.04 parts per million and a specific conductance of less than 0.10 mho with about 1.2 to 3 parts by volume of Willard Water as prepared in accordance with U.S. Pat. No. 3,893,943. The bactericidal liquid concentrate in the amount of 3.5 to 12 ml in one liter of gel formulation is applied directly to a skin surface area having a burn or other dermal lesion to protect the area from bacterial contamination.
    Type: Grant
    Filed: June 24, 2002
    Date of Patent: February 17, 2004
    Assignee: Aqua Med, Inc.
    Inventor: John D. Young
  • Patent number: 6663874
    Abstract: A composition for use by animals, including humans, to alleviate pain and/or inflammation around a painful joint, joint replacement surgery site, muscle, tendon, and/or ligament. A method to ameliorate pain and/or inflammation in or around a joint, muscle, tendon, and/or ligament, by topically applying Applicant's composition.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: December 16, 2003
    Inventor: Victor Stevens
  • Publication number: 20030190303
    Abstract: The present invention relates to pharmaceutical compositions and methods for treating allergic disorders characterized by a local immune response including inflammatory skin reactions, asthma, and arthritis.
    Type: Application
    Filed: April 10, 1998
    Publication date: October 9, 2003
    Inventors: IAN KIMBER, MARIE CUMBERBATCH, REBECCA J. DEARMAN, ORLA M. CONNEELY, PAULINE WARD
  • Patent number: 6582709
    Abstract: The preset invention relates to a pharmaceutical cream composition for topical application for the treatment of skin disorders and skin diseases, comprising 1-6 wt. % Dead Sea Mud as an active ingredient. Said composition is for use in treating skin disorders and skin diseases such as psoriasis, saborrehic dermatitis, xerosis, attopic dermatitis, eczema, diaper rush, skin burns of stage I and sensitive skin. Said cream composition is also for use as a leave-on cosmetic cream for beautifying and enhancing the skin appearance. In addition to Dead Sea Mud said composition comprises ingredients suitable for the preparation of cosmetic cream. Said cream can further comprises up to 4 wt % Dead Sea water.
    Type: Grant
    Filed: October 15, 2001
    Date of Patent: June 24, 2003
    Assignee: Dead Sea Laboratories Ltd.
    Inventors: Zeev Maor, Shaul Yehuda, Shlomo Magdassi, Galit Meshulam-Simon, Yona Gavrieli, Zivn Gilad, Dov Efron
  • Patent number: 6572848
    Abstract: Agonists of chlorine/potassium channel receptor, for example taurine, gamma-aminobutyric acid (GABA), isoguvacin, isonipecotic acid, 4,5,6,7-tetrahydroisoxazolo-(5,4-c)pyrid-3(2H)-one, a benzodiazepine, steroids, and cromakalim, pinacidil, nicorandil and minoxidil, are well suited for treating sensitive human skin and are especially useful for treating/eliminating skin itching, pruritus, tautness, tingling and/or erythema.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: June 3, 2003
    Assignee: Societe L'Oreal S.A.
    Inventors: Lionel Breton, Olivier De Lacharriere, Isabelle Nonotte
  • Patent number: 6559183
    Abstract: The present invention relates to a composition comprising a nano-emulsion that contains 5-aminolevulinic acid as well as a carrier in an aqueous phase. This invention also relates to a pharmaceutical preparation containing this composition. The nano-emulsions of this type can be used in photodynamic therapy as well as in the photodiagnostic detection of proliferatives cells.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: May 6, 2003
    Assignee: ASAT AG Applied Science & Technology
    Inventors: Hans W. Schmid, Gerd Burmeister
  • Patent number: 6544502
    Abstract: A method for treating a skin condition by intimately combining a water soluble antibiotic with the keratin layer of the outermost layer of the cleansed epidermis. The antibiotic is dissolved in the alkaline fraction of an electrolyzed water. The solution is characterized by the absence of hydrolysis products, turbidity, and loss of potency of the antibiotic. The aqueous solution is applied to the treatment area where the water is absorbed by the keratin and the antibiotic is carried into intimate contact with the keratin after which the water is evaporated leaving the antibiotic dispersed across the treatment area.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: April 8, 2003
    Assignee: Wasatch Pharmaceutical Inc.
    Inventor: Gary V. Heesch
  • Patent number: 6503523
    Abstract: The invention relates to topical preparations containing one or more compounds chosen from group (A), which consists of vitamin A-acid or its derivatives, combined with one or more compounds chosen from group (B), which consists of ubiquinones and their derivatives and plastoquinones and their derivatives.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: January 7, 2003
    Assignee: GS Development A.B.
    Inventors: Udo Hoppe, Volker Schreiner, Franz Stäb
  • Patent number: 6444709
    Abstract: The invention relates to novel heteroethynylenic compounds having the general formula (I): as well as to the use of these compounds in pharmaceutical compositions intended for use in human or veterinary medicine (dermatological, rheumatic, respiratory, cardiovascular and ophthalmological complaints in particular), or alternatively in cosmetic compositions.
    Type: Grant
    Filed: February 7, 2000
    Date of Patent: September 3, 2002
    Assignee: Galderma Research & Development S.N.C.
    Inventors: Philippe Diaz, Jean-Michel Bernardon
  • Patent number: 6440978
    Abstract: The present invention provides a therapeutic agent for dermatitis, particularly a therapeutic agent for atopic dermatitis, which is very safe and which shows few adverse side-effects in comparison to, for example, steroidal agents. The present invention relates to a therapeutic agent containing a compound represented by the following formula (I) or a pharmaceutically acceptable salt or hydrate thereof as an effective ingredient: wherein R is hydrogen or a halogen. The therapeutic agent for dermatitis according to the present invention effectively and in a dose-dependent manner suppresses antigen-induced swelling in a mouse ear, a recognized animal model for atopic dermatitis, and suppresses the antigen-induced flare-up reaction in mice which occurred with the swelling reaction. In addition, no adverse reaction in the skin are observed.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: August 27, 2002
    Assignee: Nippon Zoki Pharmaceutical Co., Ltd.
    Inventors: Haruo Yoshii, Akihiro Fujita
  • Patent number: 6436926
    Abstract: Compositions comprising 4,4′-methylenebis(tetrahydro-1,2,4-thiadiazine) 1,1,1′,1′,-tetraoxide and their use in treating dermatologic disorders are disclosed.
    Type: Grant
    Filed: September 4, 2001
    Date of Patent: August 20, 2002
    Assignee: MedPointe, Inc.
    Inventor: James C. Costin
  • Patent number: 6423343
    Abstract: This invention relates to a method for treating inflammatory symptoms such as burning, redness, itching, swelling and pain which accompany skin disorders other than wounds of the skin. The method comprising topical application of a topical medicinal composition comprising a non-interlinked, particulate bioactive glass mixed with a topical medicinal carrier to the site of the skin disorder.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: July 23, 2002
    Assignee: USBiomaterials Corporation
    Inventors: Sean Lee, James L. Meyers
  • Patent number: 6416790
    Abstract: The concentrate is a liquid mixture of about 1000 parts by volume of ultra pure water having an electrical resistance of 16-26 megohms, total dissolved solids of less than 0.04 parts per million and a specific conductance of less than 0.10 microhmo to about 1.2 to 3 parts by volume of Willard Water as prepared in accordance with U.S. Pat. No. 3,893,943. The liquid concentrate is applied directly to a skin surface area having a burn or other dermal lesion to protect the area from bacterial contamination.
    Type: Grant
    Filed: March 13, 2000
    Date of Patent: July 9, 2002
    Assignee: Aqua Med, Inc.
    Inventor: John D. Young
  • Patent number: 6403656
    Abstract: The invention concerns the use of at least one activator of receptors of the PPAR-&ggr; type for preparing a pharmaceutical composition for treating skin disorders related to an anomaly of the differentiation of epidermic cells.
    Type: Grant
    Filed: September 7, 2000
    Date of Patent: June 11, 2002
    Assignee: Galderma Research & Development S.N.C
    Inventors: Michel Rivier, Irina Safonova, Serge Michel
  • Patent number: 6399108
    Abstract: The present invention is directed to methods and compositions for treating skin disorders. The present invention is easily administered and can be used for both humans and animals. The compositions of the present invention comprise borate compounds and provide relief from skin disorder symptoms and lesions. Additionally, the present invention can be used to provide long term maintenance of symptom-free skin.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: June 4, 2002
    Assignee: P.H.C., Inc.
    Inventor: Don H. Girvan
  • Publication number: 20020061284
    Abstract: The present application relates to cosmetic compositions containing, in a cosmetically acceptable aqueous medium, at least one polyorganosiloxane and an acrylic terpolymer, as well as to the use of these compositions for treating keratinous material, in particular the skin or the hair.
    Type: Application
    Filed: June 14, 1999
    Publication date: May 23, 2002
    Inventor: CHRISTINE DUPUIS
  • Patent number: 6379713
    Abstract: A method of treatment for a mammal in need of analgesia from an itching skin comprising applying by directional friction against the skin proximate to the itch a composition consisting essentially of dry elemental iodine in the form of an amorphous condensate. The method is found effective in producing analgesia to the affected skin within 1 to 5 minutes after application.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: April 30, 2002
    Inventor: André Reiss
  • Publication number: 20020040034
    Abstract: Methods utilizing descarboethoxyloratadine (“DCL”), for the treatment of allergic disorders, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. Also included are methods for the treatment of allergic asthma using DCL and either a decongestant or a leukotriene inhibitor, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. The invention also encompasses the administration of DCL in a nasal or oral spray.
    Type: Application
    Filed: April 24, 2000
    Publication date: April 4, 2002
    Inventors: Dean A. Handley, Paul D. Rubin
  • Patent number: 6355649
    Abstract: The instant invention involves a method of treating and/or reversing androgenic alopecia and promoting hair growth, and methods of treating acne vulgaris, seborrhea, and female hirsutism, by administering to a patient in need of such treatment a 5&agr;-reductase 2 inhibitor, such as finasteride, in a dosage amount under 5 mgs/day.
    Type: Grant
    Filed: October 30, 2000
    Date of Patent: March 12, 2002
    Assignee: Merck & Co., Inc.
    Inventors: Glenn J. Gormley, Keith D. Kaufman, Elizabeth Stoner, Joanne Waldstreicher
  • Patent number: 6342486
    Abstract: A method for treatment of skin includes topical application of a composition containing a therapeutically effective amount of a 1,3-beta-glucan ether derivative. Such application effectively provides treatment and/or prophylaxis of various skin-related problems, such as neurodermatitis and psoriasis, and reduces the evidence of aging by minimizing wrinkles. In an advantageous embodiment, the glucan ether derivative is present in the composition in a range of concentration of about 0.002% to about 8% by weight. In another embodiment the glucan ether derivative is advantageously carboxymethyl glucan sodium salt.
    Type: Grant
    Filed: July 18, 1997
    Date of Patent: January 29, 2002
    Assignee: Mibelle AG Cosmetics
    Inventors: Fred Zülli, Franz Suter