Low Shear Followed By High Shear Patents (Class 516/930)
  • Patent number: 7683098
    Abstract: Methods for manufacturing nanomaterial dispersions, such as nanomaterial concentrates, and related nanotechnology are provided. The nanomaterial concentrates provided can be more cheaply stored and transported compared to non-concentrate nanomaterial forms.
    Type: Grant
    Filed: June 21, 2005
    Date of Patent: March 23, 2010
    Assignee: PPG Industries Ohio, Inc.
    Inventor: Tapesh Yadav
  • Patent number: 7214717
    Abstract: A fractionable polydisperse stable double oil-in-water emulsion, having 50 to 95 wt. % relative to the total weight of the double emulsion, droplets of an invert monodisperse emulsion Ei dispersed in a continuous aqueous phase. The continuous aqueous phase includes a polysaccharide thickening agent in a proportion of 1 to 10 wt. % relative to the total weight of the continuous aqueous phase, a water-soluble ethylene oxide and propylene oxide block copolymer as surfactant, and an osmotic pressure balancing agent. The emulsion Ei has a viscosity not higher than the viscosity of the continuous aqueous phase and has 50 to 95 wt. %, relative to the total weight of Ei, droplets of an internal aqueous phase dispersed in an oily phase. The internal aqueous phase includes an active hydrophilic substance and the oily phase includes poly glycerol polyricinoleate as surfactant.
    Type: Grant
    Filed: September 4, 2000
    Date of Patent: May 8, 2007
    Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Jérôme Michel Jaques Bibette, Fernando Leal Calderon, Philippe Gorria
  • Patent number: 6716885
    Abstract: A storage-stable aerated gel composition comprising 30 to 97% by weight of water, 0.2 to 5% by weight of a gelling agent selected from xanthan gum, sodium alginate and neutralized carboxyvinyl polymer and 2 to 5% by weight of a fine particulate hydrophobic silicone-treated silica having a surface area of from 80 to 300 m2/g. The composition is in the form of fine particles of an aqueous gel containing the water and the gelling agent, the surface of which particles are coated with a coating of the finely divided particulate hydrophobic silica. The gel composition is prepared by mixing, under high shear conditions, the water and the fine particulate silica, and then adding to the resulting mixture, the gelling agent and mixing under high shear conditions.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: April 6, 2004
    Assignee: Sorex Limited
    Inventors: Roland Twydell, Lesley Le Quesne
  • Patent number: 5985941
    Abstract: A heat and shelf-stable oil-in-water emulsion useful as a tissue or cell-selective delivery vehicle. Radioactive or stable, synthetic or semi-synthetic polyhalogenated triglycerides, such as 2-oleoylglycerol-1,3-bis[7-(3-amino-2,4,6-triiodophenyl)heptanoate] or 2-oleoylglycerol-1,3-bis[.omega.-(3,5-bis-trifluoromethyl)hepatanoate] or phenyl acetate, can be incorporated into the lipophilic core of a lipoprotein-like emulsion particle. The lipophilic core is surrounded by a phospholipid membrane comprising cholesterol and apolipoproteins. For hepatocyte-selective delivery, the emulsion is chylomicron remnant-like by being in a size range of 50 to 200 nm as measured by number weighting analysis with a narrow size distribution (<2% greater than 300 nm) and having a composition simulating naturally-occurring chylomicron remnants. Use of cholesterol in the emulsion formula facilitates association of apolipoproteins, especially Apo E which are recognized by liver cells and necessary for binding and uptake.
    Type: Grant
    Filed: June 30, 1995
    Date of Patent: November 16, 1999
    Assignee: University of Michigan
    Inventors: Raymond E. Counsell, Marc A. Longino, Jamey P. Weichert, Douglas A. Bakan
  • Patent number: 5980592
    Abstract: A method and a plant for processing problematic, organic, chemical wastes for the disposal thereof. The different types of waste are collected in separate portions and the liquid waste portions are pooled, and the resulting liquid mixture is left to separate into a number of fractions. Each viscous or solid waste portions is subjected to a compatibility test with a liquid fraction. The waste portions are admixed with an amount of a compatible liquid fraction, ensuring that a workable mixture is obtained. The different mixtures are gradually mixed and a mixed and workable buffer portion is obtained. The buffer portion or a portion thereof is subjected to grinding at a high shear. A pumpable, combustible dispersion is obtained, which can be incinerated without any risk of explosions.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: November 9, 1999
    Assignee: RAG Umweltrohstoffe GmbH
    Inventor: Dennis S.o slashed.gaard
  • Patent number: RE38459
    Abstract: An injectable physiologically acceptable aqueous phase fluorocarbon emulsion, which has substantially no free fluorocarbon, has an excellent stability is prepared by a process of the invention. Typically, more than about 99.8 wt. % of the fluorocarbon remains in the size range of about 0.2 to 0.4 microns even after being stored at room temperature for one year or more in sealed containers under a non-oxidizing atmosphere. The emulsion is useful in medical applications, for example, coronary angioplasty, cancer therapy, among others.
    Type: Grant
    Filed: January 21, 1999
    Date of Patent: March 9, 2004
    Assignee: Thomas Jefferson University
    Inventors: Stuart Raynolds, Robert H. Dettre