Abstract: The present invention is generally directed to thiol quantitation assays, methods of performing the assays, and compounds used in the assays. It is more specifically directed to assays that include one or more disulfides and related molecules and methods. The disulfides contain a FRET pair.

Abstract: The present invention relates to compounds suitable as modulators of protein misfolding and/or protein aggregation. The compounds are particularly suitable as inhibitors of amyloid aggregate formation and/or modulators of amyloid surface properties, and/or as activators of degradation or reduction of amyloid aggregates.

Abstract: Poly-azo compound selected from the group consisting compounds of the formula (I) and compounds of the formula (II), (wherein, Me represents copper, nickel, zinc or iron, A represents a naphthyl group having 1 to 3 sulfonic groups and further optionally having an alkyl group or alkoxy group, R1 and R2 represent each independently a hydrogen atom, alkyl group or alkoxy group, and R3 represents an amino group or hydroxyl group.).

Abstract: A hardness indicator composition, and a method of water hardness analysis, capable of measuring hardness even with higher-hardness water without requiring titration by a two-liquid system. The hardness indicator composition is formulated of a metal indicator with a desensitizer added thereto.

Abstract: Named compounds are useful in making dry analytical elements for assaying lithium in serum. The compounds have the general structure: ##STR1## wherein R, R.sub.1, R.sub.2 and X are as presented below:______________________________________ R R.sub.1 R.sub.2 X ______________________________________ n-C.sub.12 H.sub.25 SO.sub.2 CH.sub.3 CH.sub.3 CH n-C.sub.12 H.sub.25 NO.sub.2 CH.sub.3 CH CH.sub.3 SO.sub.2 N(n-C.sub.6 H.sub.13).sub.2 CH.sub.3 CH CH.sub.2 C.sub.6 H.sub.5 SO.sub.2 N(n-C.sub.6 H.sub.13).sub.2 CH.sub.3 CH CH.sub.2 C.sub.6 H.sub.5 SO.sub.2 N(CH.sub.3)-n-C.sub.18 H.sub.37 CH.sub.3 CH CH.sub.3 NO.sub.2 n-C.sub.7 H.sub.15 CH n-C.sub.12 H.sub.25 H CH.sub.

Abstract: A fibre-reactive azo dyestuff of the formula ##STR1## in which X is alkyl or alkoxy with 1 to 4 carbon atoms, carboxyl or halogen, n is 1, 2 or 3, m is 0 or 1, p is 0 or 1 and q is 0 or 1 and the benzene or naphthalene rings A, B and B' can contain further substituents in addition to SO.sub.3 H groups. The dyestuffs of the invention are suitable inter alia, for dyeing and printing silk, leather, wool, high molecular weight polyamide fibres and high molecular weight polyurethanes, but especially cellulose-containing materials having a fibrous structure.

Abstract: A disazo reaction dyestuff for cellulose fibers which is of the formula: ##STR1## wherein D is a residue of a monoazo dye, R.sup.1 is hydrogen or lower alkyl, and X is a group: ##STR2## wherein R.sup.2 and R.sup.3 are each hydrogen, methyl, methoxy or --SO.sub.3 M, Y is an aromatic or aliphatic divalent residue and M is hydrogen or an alkali metal.

Abstract: Physiologically acceptable cation salts of (2-alkoxy-4-sulfonyl-5-alkylphenyl)azo-1-hydroxynaphthalene sulfonic acids useful as blue-red colorants for textile fabrics, cellulosic fibers and edible compositions are prepared by diazotizing 2-alkoxy-4-sulfonyl-5-alkylanilines and coupling the resulting diazo compounds to a 1-hydroxynaphthalene mono- or disulfonic acid.

Abstract: The disodium salt of 1-[(6-methoxy-4-sulfo-3-methylphenyl)azo]-2-naphthol-6-sulfonic acid (FD and C Red 40), the disodium salt of 1-[(4-sulfophenyl)azo]-2-naphthol-6-sulfonic acid (FD and C Yellow 6), the trisodium salt of 1-[1-(4-sulfonaphthyl)azo]-2-naphthol-3,6-disulfonic acid (FD and C Red 2), the disodium salt of 2-[1-(4-sulfonaphthyl)azo]-1-naphthol-4-sulfonic acid (Carmoisine) and the sodium salt of 2-(2-quinolyl)-1,3-indanedione-sulfonic acid (D and C Yellow 10) are prepared and purified in high yield and in a high state of purity by subjecting their aqueous reaction mixtures to ultrafiltration through a membrane of such structure and under such conditions that the impurities are separated from the reaction mixtures, and the products are concentrated in high purity concentrates from which the products can be isolated directly by evaporation of the solvent.

Abstract: Water-soluble azo compounds which, in the free acid form, are represented by the formula: ##STR1## wherein one of X and Y is hydrogen and the other is --SO.sub.3 H; one of A and B is hydrogen and the other is --SO.sub.3 H; each of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is independently hydrogen, methyl group, ethyl group, methoxy group, ethoxy group, acylamino group or ureido group; and each of R.sub.5 and R.sub.6 is independently hydrogen, methyl group, ethyl group, methoxy group, ethoxy group, acylamino group, chlorine, hydroxyl group or carboxyl group, and a method for dyeing cellulose fibers, blended yarn fabrics of cellulose fibers with other kinds of fibers, particularly with polyester fibers, using the said compounds.

Abstract: The halogenated azo dyestuffs of the present invention possess fire-proofing and antimicrobial properties and have the following general formula: ##STR1##