Oxygen Containing Six-membered Hetero Ring (e.g., Oxathiane, Etc.) Patents (Class 536/6)
  • Derivative of desglucohellebrin and therapeutic use
    Patent number: 4038386
    Abstract: Compounds are prepared of the formula ##STR1## The compounds of the invention possess valuable pharmacodynamic properties. They especially have a positive inotropic effect which is particularly noted in oral or enteral application. In contrast to the known compounds the compounds of the invention have more favorable pharmacological or pharmaceutical properties.
    Type: Grant
    Filed: April 3, 1975
    Date of Patent: July 26, 1977
    Assignee: Deutsch Gold- und Silber-Scheideanstalt Vormals Roessler
    Inventors: Otto Isaac, Klaus Posselt, Horst Uthemann
  • 3.beta.-(4-Oxo-.a lpha.-L-rhamnosyl)-.beta.-hydroxy-bufa-4,20,22-trienolide
    Patent number: 4031212
    Abstract: The compound of the formula ##STR1## which is useful as a cardiotonic.
    Type: Grant
    Filed: July 30, 1975
    Date of Patent: June 21, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Walter Losel, Werner Traunecker, Wolfgang Hoefke
  • 3.beta.-(.alpha.-L-althromethylosyl)-14.beta.-hydroxy-bufa-4,20,22-trieno lide and acylated derivatives thereof
    Patent number: 4021547
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are hydrogen or carboxylic acyl, particularly acetyl, benzoyl or p-nitro-benzoyl; the compounds are useful as cardiotonics.
    Type: Grant
    Filed: January 21, 1976
    Date of Patent: May 3, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Walter Losel, Werner Traunecker, Wolfgang Hoefke
  • Acyl derivatives of proscillaridin A
    Patent number: 3987031
    Abstract: Compounds of the formula ##SPC1##Wherein R.sub.3 is hydrogen, methyl, cyclopropylcarbonyl, benzoyl or thenoyl, andWhen R.sub.3 is hydrogen, R.sub.2 is phenyl, phenethyl, phenyl-propyl, chloro-propyl, chloro-phenyl, fluoro-phenyl, cycloalkyl of 3 to 8 carbon atoms or (cycloalkyl of 5 to 6 carbon atoms)-methyl, orWhen R.sub.3 is other than hydrogen, R.sub.2 is methyl, ethyl, phenyl, cyclopropyl or chloropropyl; the compounds are useful as cardiotonics.
    Type: Grant
    Filed: December 5, 1973
    Date of Patent: October 19, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Walter Losel, Herbert Merz, Wolfgang Hoefke, Werner Traunecker
  • Derivatives of 3.beta.-(4'-oxo-.alpha.-L-rhamnosyl)-14.beta.-hydroxy-bufa-4,20,22-trien olide
    Patent number: 3981992
    Abstract: Compounds of the formula ##SPC1##WhereinR is ##SPC2##R.sub.1 is hydrogen or alkoxy of 1 to 4 carbon atoms, andR.sub.2 is alkoxy of 1 to 4 carbon atoms, orR.sub.1 and R.sub.2 together are oxygen;The compounds are useful as cardiotonics.
    Type: Grant
    Filed: July 30, 1975
    Date of Patent: September 21, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Walter Losel, Werner Traunecker, Wolfgang Hoefke