Halogen Containing Compound Utilized In Process Patents (Class 536/75)
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Publication number: 20130131333Abstract: This invention provides cellulose ester interpolymers, and methods of oxidizing cellulose interpolymers and cellulose ester interpolymers. The invention also provides routes to access carboxylated cellulose ester derivatives with high acid numbers wherein the carboxyl group is attached directly to the cellulose backbone by a carbon-carbon bond. Through functionalization of an intermediate aldehyde, the corresponding cationic or zwitterionic cellulose ester derivatives can also be accessed. The interpolymers of the present invention have a number of end-use applications, for example, as binder resins in various types of coating compositions and as drug delivery agents.Type: ApplicationFiled: December 27, 2012Publication date: May 23, 2013Applicant: Eastman Chemical CompanyInventor: Eastman Chemical Company
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Publication number: 20120328877Abstract: The present invention is cellulose nanofibers having an average polymerization degree of 600 to 30000, an aspect ratio of 20 to 10000, an average diameter of 1 nm to 800 nm, and an I?-type crystal peak in an X-ray diffraction pattern.Type: ApplicationFiled: September 5, 2012Publication date: December 27, 2012Applicant: Olympus CorporationInventors: KOHEI SHIRAMIZU, Naohito Shiga, Takashi Magara, Kohei Oguni, Lianzhen Lin
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Publication number: 20120238741Abstract: Ionic liquids and cellulose ester compositions and processes for producing ionic liquids and cellulose esters. Cellulose esters can be produced by subjecting a cellulose-ionic liquid solution comprising cellulose, one or more ionic liquids, and one or more co-solvents to esterification to thereby produce an esterified medium comprising a cellulose ester. The co-solvents employed in the present invention can be either miscible or immiscible with the cellulose-ionic liquid solution but can be readily dispersed or soluble in the esterified medium.Type: ApplicationFiled: June 1, 2012Publication date: September 20, 2012Applicant: EASTMAN CHEMICAL COMPANYInventors: Charles Michael Buchanan, Norma Lindsey Buchanan
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Publication number: 20120238742Abstract: Ionic liquids and cellulose ester compositions and processes for producing ionic liquids and cellulose esters. Cellulose esters can be produced by subjecting a cellulose-ionic liquid solution comprising cellulose, one or more ionic liquids, and one or more co-solvents to esterification to thereby produce an esterified medium comprising a cellulose ester. The co-solvents employed in the present invention can be either miscible or immiscible with the cellulose-ionic liquid solution but can be readily dispersed or soluble in the esterified medium.Type: ApplicationFiled: June 1, 2012Publication date: September 20, 2012Applicant: EASTMAN CHEMICAL COMPANYInventors: Charles Michael Buchanan, Norma Lindsey Buchanan
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Patent number: 7345166Abstract: Novel antenna polymers characterized by a polymeric background of a biodegradable water soluble polymer and chromophores chemically bonded to the polymeric background have been found to be useful as photocatalysts in aqueous media. On completion of the desired photochemical reaction, the residual medium can safely be discharged to the natural environment as the catalyst residues undergo biodegradation to form environmentally harmless products.Type: GrantFiled: October 23, 2003Date of Patent: March 18, 2008Inventors: James E. Guillet, Maria Nowakowska
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Patent number: 6293972Abstract: In the fluorinated cellulosic material obtained by a method for fluorinating a cellulosic material by reacting a cellulosic material selected from the group consisting of cellulose material and lignocellulose material with at least one fluorine-containing compound selected from the group consisting of fluorine-containing olefin compound, fluorine-containing acrylate compound and fluorine-containing methacrylate compound in an organic solvent in the presence of a catalyst, not only the surface but also the inside of the cellulose and/or lignocellulose materials are modified and high performance of the cellulose and/or lignocellulose materials is realized.Type: GrantFiled: September 29, 1998Date of Patent: September 25, 2001Assignee: Daikin Industries Ltd.Inventors: Fumihiko Yamaguchi, Eiji Sakamoto
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Patent number: 6162794Abstract: The invention relates to compounds of the formula: ##STR1## and to pharmaceutically acceptable salts thereof, wherein R and Z are as defined herein.The invention also relates to pharmaceutical compositions containing the compounds of formula I, methods of using said compounds of formula I in the treatment of infections and methods of preparing said compounds of formula I.Type: GrantFiled: July 20, 1999Date of Patent: December 19, 2000Assignee: Pfizer Inc.Inventor: Yong-Jin Wu
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Patent number: 6054435Abstract: The instant invention provides novel macrolide compounds and compositions useful in treating bacterial infections. Also provided are processes for preparing same.Type: GrantFiled: March 19, 1999Date of Patent: April 25, 2000Assignee: Abbott LaboratoriesInventors: Yat Sun Or, Richard F. Clark, Zhenkun Ma, Michael John Rupp
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Patent number: 5919916Abstract: Novel 6-O-alkyl derivatives of erythronolide B are provided. A process for the preparation of 6-O-alkyl derivatives of erythronolide B using erythromycin B is also provided. A process for preparing 6-O-alkyl derivatives of erythromycin C using novel 6-O-alkyl derivatives of erythronolide B is further provided.Type: GrantFiled: December 1, 1997Date of Patent: July 6, 1999Assignee: Abbott LaboratoriesInventors: H. Eugene Gracey, Stephen H. Montgomery, David A. Riley, Jih-Hua Liu
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Patent number: 5869629Abstract: The preparation of azitromycin dihydrate from 9-deoxo-9a-aza-11,12-deoxy-9a-methyl-9a-homoerythromycin A 11,12-hydrogenorthoborate, obtained by a step by step process starting from 9-deoxo-6-deoxy-6,9-epoxy-9,9a-dihydro-9a-azahomoerythromycin A is a process which takes place under mild conditions and with good yields.Type: GrantFiled: July 11, 1997Date of Patent: February 9, 1999Assignee: Asturpharma, S.A.Inventors: D. Miguel Santos Bayod Jasanda, D. Jose Ramon Fernandez Gonzalez
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Patent number: 5864023Abstract: The disclosed invention relates to novel 3'-N-O, 9-O-oxime protected, 6-O-alkyl erthyromycin derivatives, a process of preparing the same. The invention also relates to a process of preparing 6-O-alkyl erythromycin A by eliminating the 3'-N-oxide group and 9-O-oxime protecting groups and optionally deprotecting the hydroxy groups at the 2'- and 4"- positions under suitable reaction conditions.Type: GrantFiled: February 13, 1997Date of Patent: January 26, 1999Assignee: Abbott LaboratoriesInventors: Yi-Yin Ku, David A. Riley
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Patent number: 5854219Abstract: The invention relates to 9-N-ethenyl derivatives of 9 (S)-erythromycylamine, new semisynthetic antibiotics of the macrolide class of the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and represent nitryl, a carboxyl group of the formula COOR.sup.3, wherein R.sup.3 represents a C.sub.1 -C.sub.4 alkyl group, or a keto group of the formula COR.sup.4, wherein R.sup.4 represents a C.sub.1 -C.sub.4 alkyl group, to their pharmaceutically acceptable addition salts with inorganic or organic acids, to a process for their preparation, to a process for the preparation of the pharmaceutical compositions as well as to the use of the obtained pharmaceutical compositions in the treatment of bacterial infections.Type: GrantFiled: October 23, 1997Date of Patent: December 29, 1998Assignee: PLIVA, farmaceutska, kemijska, prehrambena i kozmeticka industrija, dionicko drustvoInventors: Nedjeljko Kujundzic, Dina Pavlovic, Gabrijela Kobrehel, Gorjana Lazarevski, Zeljko Kelneric
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Patent number: 5844105Abstract: The present invention provides a process for the preparation of 6-O-methylerythromycin A Form II comprising converting erythromycin A to 6-O-methylerythromycin A and treating the 6-O-methylerythromycin A with a number of common organic solvents or mixtures of common organic solvents.Type: GrantFiled: July 29, 1996Date of Patent: December 1, 1998Assignee: Abbott LaboratoriesInventors: Jih-Hua Liu, David A. Riley
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Patent number: 5840861Abstract: New A83543 components, including fermentation products A83543K, A835430, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.Type: GrantFiled: February 8, 1995Date of Patent: November 24, 1998Assignee: DowElancoInventors: Jon S. Mynderse, Mary C. Broughton, Walter M. Nakatsukasa, James A. Mabe, Jan R. Turner, Lawrence Creemer, Mary L. B. Huber, Herbert A. Kirst, James W. Martin
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Patent number: 5770726Abstract: The present invention relates to a process for preparing a substituted cellulose acetoacetate alkanoate without using a carboxamide/lithium chloride solvent system. The process involves contacting cellulose in a carboxylic acid diluent with an acetylating compound selected from the group consisting of a carboxylic acid anhydride and an acid chloride, an acetoacetylating compound selected from the group consisting of diketene, an alkyl acetoacetate and 2,2,6-trimethyl-4H-1,3-dioxin-4-one, and a mineral acid catalyst under conditions and in a molar ratio sufficient to cause the cellulose, acetylating compound and acetoacetylating compound to react to produce a substituted cellulose acetoacetate alkanoate.Type: GrantFiled: March 10, 1997Date of Patent: June 23, 1998Assignee: Eastman Chemical CompanyInventors: Chung Ming Kuo, Kevin Joseph Edgar
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Patent number: 5670486Abstract: New A83543 components, including fermentation products A83543K, A83543O, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.Type: GrantFiled: June 7, 1995Date of Patent: September 23, 1997Assignee: DowElancoInventors: Jon S. Mynderse, James A. Mabe, Jan R. Turner, Mary L. B. Huber, Mary C. Broughton, Walter M. Nakatsukasa, Lawrence Creemer, Herbert A. Kirst, James W. Martin
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Patent number: 5670632Abstract: A process is disclosed for recovering isoflavones from a soy extract comprises:dripping the soy extract dissolved in the aqueous solvent through a chromatographic column from top to bottom packed with a ground highly polar cationic exchange resin containing sulfonic acid functional groups of the formula:{MHSO.sub.3 }--Nawherein MH is the particular adsorbent resin on which the sulfonic acid functional groups are immobilized and wherein the resin is charged with sodium ions which replace the hydrogen ions of sulfonic acid, to selectively adsorb the 7-glycosyl-isoflavones directly on the sulfonate sulfur atom while the undesired proteins and glycosides other than the 7-glycosyl-isoflavones are eluted through the chromatographic column and are removed.Type: GrantFiled: January 18, 1996Date of Patent: September 23, 1997Assignee: ACDS Technologies, Ltd.Inventor: Abas Chaihorsky
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Patent number: 5670364Abstract: New A83543 components, including fermentation products A83543K, A835430, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.Type: GrantFiled: June 7, 1995Date of Patent: September 23, 1997Assignee: DowElancoInventors: Jon S. Mynderse, James A. Mabe, Jan R. Turner, Mary L. B. Huber, Mary C. Broughton, Walter M. Nakatsukasa, Lawrence Creemer, Herbert A. Kirst, James W. Martin
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Patent number: 5614614Abstract: Novel intermediates for the preparation of the compounds of Formula I wherein the substituents are as defined in the specification.Type: GrantFiled: February 21, 1995Date of Patent: March 25, 1997Assignee: Roussel UclafInventors: Constantin Agouridas, Alain Bonnefoy, Jean-Francois Chantot, Alexis Denis, Odile Le Martret
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Patent number: 5552533Abstract: (8S)-8-fluoroerythromycins are prepared by reacting 8,9-anhydroerythromycin 6,9-hemiacetals or an N-oxide thereof with a carboxylic acid and an N-F fluorinating agent. The anhydro starting material may be prepared in situ from erythromycins or an N-oxide derivative thereof. The (8S)-8-fluoroerythromycin products are useful antibacterial agents.Type: GrantFiled: September 14, 1994Date of Patent: September 3, 1996Assignee: AlliedSignal Inc.Inventors: Andrew J. Poss, George A. Shia
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Patent number: 5516673Abstract: Polymers containing a plurality of free hydroxy groups, such as cellulose, agarose or polyvinyl alcohol, are contacted in absence of reactants for hydroxy groups, with at least one N-heterocyclic compound, e.g. pyridine, pyrrole, pyridazine, their partially or fully hydrogenated analogs and any of these which may be substituted, in a pre-activation step prior to reaction with reactant for free hydroxy groups in the polymer, the polymer-bound residue of which reactant may be thereafter reacted in turn with amino compounds containing at least one unsubstituted N-attached hydrogen atom, e.g. proteins, thereby to form amine-polymer conjugates. The invention further relates to a powder, bandage, patch or like cover for application to wounds which has been manufactured from polymer containing a plurality of hydroxy groups by a process which includes the step of providing an amine conjugated to the polymer; the amine may be, e.g., trypsin, chymotrypsin, lysozyme, collagenase, albumin and hyaluronidase.Type: GrantFiled: February 10, 1994Date of Patent: May 14, 1996Assignee: Bar Ilan UniversityInventors: Shlomo Margel, Sophia Sturchak
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Patent number: 5378828Abstract: The present invention provides a process for the preparation of water soluble alkali metal salts of cellulose sulfate having a degree of substitution ranging from 1 to 3 and viscosity of 1 percent aqueous solution in excess of 20 centipoises (cps). The process involves the use of chlorosulfuric acid as a sulfonating agent in the presence of pyridine used as a solvent in reaction. The important steps of the process for preparation of the water soluble salts include presoaking of the cellulose in pyridine followed by washing the pyridine salt with an alcohol such as methanol and reacting saturated alkali metal bicarbonate or carbonate solutions with the sulfonated cellulose.Type: GrantFiled: September 2, 1993Date of Patent: January 3, 1995Assignee: Dextran Products LimitedInventors: Thomas C. Usher, Natu Patel, Chhagan G. Tele
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Patent number: 5294703Abstract: Provided is a novel improved process for the preparation of .alpha.-D-cellobiose octaacetate via the acetylative degradation of cellulose or cellulose acetate. The title compound is provided in high yield and quality in a facile one-pot process, amenable to large-scale synthesis.Type: GrantFiled: April 7, 1993Date of Patent: March 15, 1994Assignee: Eastman Kodak CompanyInventors: John A. Hyatt, Tony L. Sander, D. Mark Naylor, Bobby L. Bernard
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Patent number: 5227295Abstract: An improved process for isolating A83543 factors from fermentation broth in which they are produced which comprises:a) adding an approximately equal volume of a water miscible, polar organic solvent to the fermentation broth, including the biomass thereof;b) separating the liquid phase of the resulting mixture from the biomass;c) adjusting the pH of the separated liquid phase to between about 7 and 13;d) applying the separated liquid phase directly to a column of nonfunctional, macroreticular polymer;e) eluting the A83543 components from the column with an aqueous solution of water miscible, polar organic solvent; andf) collecting the fractions containing A83543 components.Type: GrantFiled: November 8, 1991Date of Patent: July 13, 1993Assignee: DowElancoInventor: Patrick J. Baker
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Patent number: 4673736Abstract: For the synthesis of (8S)-8-fluoroerythromycins the corresponding 8,9-anhydroerythromycins 6,9-hemiketal are directly fluorinated with perchloryl fluoride.Type: GrantFiled: July 11, 1984Date of Patent: June 16, 1987Assignee: Pierrel SpAInventor: Luciano Toscano
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Patent number: 4672109Abstract: A method for the selective methylation of a hydroxy group at the 6-position of an erythromycin A derivative which comprises converting an erythromycin A derivative into an erythromycin A 9-oxime derivative, and reacting the resulting ethythromycin A 9-oxime derivative with an methylating agent.Type: GrantFiled: April 5, 1985Date of Patent: June 9, 1987Assignee: Taisho Pharmaceutical Co., Ltd.Inventors: Yoshiaki Watanabe, Shigeo Morimoto, Masami Goi, Morihiro Mitsukuchi, Takashi Adachi, Jozi Nakagami, Toshifumi Asaka, Tadashi Eguchi, Kaoru Sota
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Patent number: 4594187Abstract: The present invention is directed to a chemical process for preparing the antibiotic substance denominated antibiotic L 17054 and its pharmaceutically acceptable salts by selectively hydrolyzing teicoplanin or a factor or component thereof with a concentrated strong organic acid.Type: GrantFiled: December 11, 1984Date of Patent: June 10, 1986Assignee: Gruppo Lepetit S.p.A.Inventors: Paolo Strazzolini, Adriano Malabarba, Bruno Cavalleri
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Patent number: 4568740Abstract: Disclosed is a process for purifying Tylosin by selective adsorption of the fermentation broth previously brought to 7.5-10.0 pH on polymeric resins and by subsequent deadsorption of the purified product with a aqueous-alcoholic or aqueous-acetonic solution and further purification of the eluate by filtration through macroreticular weak anion resins.Type: GrantFiled: March 28, 1984Date of Patent: February 4, 1986Assignee: Farmitalia Carlo Erba S.p.A.Inventors: Ernesto Oppici, Onorino G. Rosa, Carlo Varesio, Giovanni Lazzari, Danillo Fabris