Nitrogen, Sulfur, Cyano Or -c(=x)-, Wherein X Is Chalcogen, Bonded Directly To The Cyclopentanohydrophenanthrene Ring System Patents (Class 540/13)
  • Patent number: 8105504
    Abstract: Organic materials which possess outstanding stability to oxidative, thermal or light-induced degradation comprise as stabilizers at least one compound of the formula (I) wherein the general symbols are as defined in claim 1. The compounds of formula I are especially useful as stabilizers for protecting polymers and lubricants against oxidative, thermal or light-induced degradation and as scavengers for oxidized developer in color photographic material.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: January 31, 2012
    Assignee: BASF SE
    Inventors: Michèle Gerster, Peter Nesvadba
  • Patent number: 7576198
    Abstract: A compound of the formula (I): wherein X is hydroxy or the like; Y is —C(?R2)—R3—R4 wherein R2 and R3 is oxygen atom or the like, R4 is hydrogen, optionally substituted alkyl, optionally substituted heteroaryl or the like; Z is hydrogen or the like; Z1 and Z3 each is independently a bond, alkylene or the like; Z2 is a bond, alkylene, —O— or the like; R1 is optionally substituted aryl, optionally substituted heteroaryl or the like; p is 0 to 2 and ring (A) is optionally substituted aromatic heterocycle, a tautomer of itself, a prodrug thereof, a pharmaceutically acceptable salt thereof or a solvate thereof has an integrase-inhibiting activity.
    Type: Grant
    Filed: August 25, 2000
    Date of Patent: August 18, 2009
    Assignee: Shionogi & Co., Ltd.
    Inventors: Takashi Kawasuji, Tomokazu Yoshinaga
  • Patent number: 7348320
    Abstract: The present invention relates to platinum complexes containing bile acid derivatives having antitumor activity
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: March 25, 2008
    Assignee: ICE s.r.l.
    Inventors: Enzo Bartoli, Beniamino Palmieri, Alessandro Medici
  • Patent number: 5149696
    Abstract: Novel 19-nor-steroids of the formula ##STR1## wherein the A and B rings have a structure selected from the group consisting of ##STR2## having hormonal properties and their preparation and intermediates.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: September 22, 1992
    Assignee: Roussel Uclaf
    Inventors: Andre Claussner, Lucien Nedelec, Daniel Philibert, Patrick Van De Velde
  • Patent number: 4904462
    Abstract: Novel, multiple-tritiated steroid-20,17-spirolactones of general Formula I ##STR1## wherein --A--B-- is --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH-- or ##STR2## and --C--D-- is ##STR3## R is hydrogen or tritium and n is 0 or 1,are usable as tracer materials for the detection of mineralocorticoid receptors.
    Type: Grant
    Filed: April 12, 1985
    Date of Patent: February 27, 1990
    Assignee: Schering Aktiengesellschaft
    Inventors: Paul-Eberhard Schulze, Klaus Nickisch, Henry Laurent, Kunhard Pollow
  • Patent number: 4762919
    Abstract: Compounds of the formula: ##STR1## wherein one X is COOR, CH.sub.2 COOR, CH(COOR).sub.2, CONHR, CH.sub.2 CONHR, or CNremaining X's are H, F, CH.sub.3, OH, COOR, CH.sub.2 COOR, CH(COOR).sub.2, CONHR, CH.sub.2 CONHR, or CN;Y is ##STR2## R is H, alkyl of 1-5 carbon atoms, or benzyl; R.sub.1 is CH.sub.2 OR.sub.3, COOR, or CONHR;R.sub.2 is H, OR.sub.3, or BR;R.sub.3 is H, COR.sub.4, or tetrahydropyranyl;R.sub.4 is alkyl of 1-5 carbon atoms or benzyl;R.sub.5 is H or COR.sub.4 ;represents a single or double bond;represents .alpha.-position, .beta.-position, or a mixture of .alpha.- and .beta.-positions; and--- represents .alpha.-position;and methods for preparing the same.
    Type: Grant
    Filed: February 12, 1986
    Date of Patent: August 9, 1988
    Assignee: Florida Agricultural and Mechanical University
    Inventor: Henry J. Lee