Abstract: Disclosed herein is a method of sorting, treating, and feeding a group of bovine animals in a feed lot, wherein the method may include the steps of determining an ob genotype of each animal, comparing the relative weight and back fat of each animal with the other animals, dividing the animals into subgroups based on weight, back fat, and ob genotype. Zilpaterol hydrochloride (ZH) may be added to a feed ration fed to animals only in selected subgroups. Each group is fed a finishing period and then moved lot to slaughter. Each slaughter date and finishing period is independent of other subgroups.
Abstract: The present invention relates to the treatment of diseases and conditions with an effective amount of a steroid having those formulas given in the specification, or a pharmacologically-acceptable salt or ester thereof. The disease or conditions treatable according to the invention include angiogenic diseases and conditions of the eye, angiogenic diseases and conditions of the brain, inflammatory diseases and conditions of the eye, inflammatory diseases and conditions of the brain and neurodegenerative diseases.
Abstract: A composition for treating cancer cells and a preparation method therefore is provided. The composition includes novel withanolide compounds derived from a Solanaceae plant, which the novel withanolide compounds have the cytotoxicity to the cancer cells.
Abstract: A novel process for making estra-4,9(10)-diene-3,17-dione steroids from readily available 19-nor-androst-4-ene-3-one steroids by a straightforward three-step process. Products of this process are important intermediates in the preparation of biologically active substances.
Type:
Application
Filed:
June 6, 2002
Publication date:
January 2, 2003
Inventors:
Verlan H. Van Rheenen, Edward J. Hessler
Abstract: .alpha.-adrenoceptor antagonists having the formula: ##STR1## which are useful to produce .alpha.-adrenoceptor antagonism, pharmaceutical compositions including these antagonists, and methods of using these antagonist to produce .alpha.-adrenoceptor antagonism in mammals.
Type:
Grant
Filed:
June 6, 1989
Date of Patent:
September 25, 1990
Assignee:
SmithKline Beecham Corporation
Inventors:
John J. Lafferty, Robert M. Demarinis, Joseph W. Venslavsky
Abstract: The method of preparing a 2.alpha.-cyano-4.alpha.,5.alpha.-epoxy-3-oxo steroid or a steroid fused at the 2- and 3-positions with a heterocyclic ring of controlled particle size which comprises dissolving the steroid in an organic solvent, precipitating the steroid by mixing a non-solvent for the steroid with the resulting solution, and controlling the time of mixing and the degree of agitation during mixing.