The Hetero Ring Shares A Ring Carbon With Two Other Cyclos Of The Polycyclo Ring System (e.g., Peri-fused, Etc.) Patents (Class 540/93)
  • Method for synthesizing furanosteroids
    Patent number: 8067583
    Abstract: The present invention is a method for synthesizing furanosteroids. The method involves intramolecular Diels-Alder/retro-Diels-Alder reaction and tautomerization of a functionalized alkyne oxazole to produce a furo[2,3-b]phenol derivative which is elaborated by intermolecular and intramolecular condensations to generate ring-A of the furanosteroid. Furanosteroids and pharmaceutical compositions containing the same are also provided.
    Type: Grant
    Filed: December 4, 2007
    Date of Patent: November 29, 2011
    Assignee: Trustees of Dartmouth College
    Inventor: Peter A. Jacobi
  • Method for synthesizing furanosteroids
    Publication number: 20090143346
    Abstract: The present invention is a method for synthesizing furanosteroids. The method involves intramolecular Diels-Alder/retro-Diels-Alder reaction and tautomerization of a functionalized alkyne oxazole to produce a furo[2,3-b]phenol derivative which is elaborated by intermolecular and intramolecular condensations to generate ring-A of the furanosteroid. Furanosteroids and pharmaceutical compositions containing the same are also provided.
    Type: Application
    Filed: December 4, 2007
    Publication date: June 4, 2009
    Inventor: Peter A. Jacobi
  • UCY1003 derivatives
    Patent number: 4952576
    Abstract: Compounds having analgesic activity which have the formula ##STR1## wherein R.sub.1 -R.sub.6 represent hydrogen or a substituent and X and Y together represent inter alia as epoxyethylene, ethylene halohydrin, haloethylene or a --CH.dbd.CH-group.
    Type: Grant
    Filed: July 22, 1988
    Date of Patent: August 28, 1990
    Assignee: Kyowa Hakko Kogyo Kabushiki Kaisha
    Inventors: Toru Yasuzawa, Hiroshi Sano, Hirofumi Nakano, Shunji Ichikawa, Katsuichi Shuto
  • Novel substance UCY1003 and process for preparing the same
    Patent number: 4914198
    Abstract: Novel substance UCY1003 produced by culturing of a microorganism has the following chemical structure and analgesic, hypotensive and antifungal activities: ##STR1##
    Type: Grant
    Filed: December 29, 1986
    Date of Patent: April 3, 1990
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Hirofumi Nakano, Mitsunobu Hara, Yoshinori Yamashita, Isao Kawamoto, Katsuhiko Ando, Hiroshi Sano, Toru Yasuzawa, Katsuichi Shuto