Phosphorus Containing Patents (Class 544/195)
  • Patent number: 10351776
    Abstract: The present invention relates to triazine-intercalated metal phosphates including at least one monomer unit of the following general formula (I): (A-H)a(+)[Mbm+(H2PO4)x1(?)(HPO4)x22(?)(PO4)x33(?)(PO3)y(?)](a?)*pH2O??(I) The invention further relates to the use thereof, the specific compounds of the general formula (I), to the preparation thereof, and to compositions.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: July 16, 2019
    Assignee: J.M. Huber Corporation
    Inventors: Hans-Günter Köstler, Trupte Dave, Wolfgang Wehner
  • Patent number: 9708538
    Abstract: The present invention relates to flame retardant compositions comprising (a) at least one triazine-intercalated metal phosphate with open framework structure with at least one monomer unit of the following general formula (I): (A-H)a(+)[Mbm+(H2PO4)x1(?)(HPO4)x22(?)(PO4)x33(?)(PO3)y(?)](a?)*pH2O??(I) and (b) at least one flame retardant component other than (a). The invention further relates to the use thereof, the specific compounds of the general formula (I) and to the preparation thereof.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: July 18, 2017
    Assignee: J.M. Huber Corporation
    Inventors: Hans-Günter Köstler, Trupte Dave, Wolfgang Wehner
  • Patent number: 9238777
    Abstract: A method for producing compounds of formula (I) in which the radical R1 is selected from —NH2, —NH2-zAz, and monovalent alkyl and aryl radicals, the radicals A are selected in each case independently of one another from the phosphoryl radicals DOPO-, DPhPO- and DPhOPO-, and the indices x, y and z, in each case independently of one another, stand for 0 or 1, wherein at least one of the indices is ?0, by reacting, in a first step, melamine or, when R1 is an alkyl or aryl radical, the corresponding alkyl or aryl guanamine, with one or more of the corresponding phosphinyl chlorides DOP-CI, DPhP-Cl and DPhOP-CI, in order to bond one or more phosphinyl radicals to the amino groups(s) of the melamine or guanamine, and in a second step oxidizing the phosphinyl radical(s) by reaction with an oxidizing agent to give the corresponding phosphoryl radical(s).
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: January 19, 2016
    Assignee: METADYNEA AUSTRIA GmbH
    Inventors: Thomas Zich, Fritz Johann Freidl, Bernadette Mehofer, Manfred Doring, Michael Ciesielski, Bettina Burk
  • Patent number: 9133617
    Abstract: A coating system comprising: (1) a liquid intumescent coating composition comprising a resin system comprising at least one polymeric component, at least one ethylenically unsaturated monomeric component, and at least one intumescent ingredient, the coating composition being curable to a solid state by free radical polymerization, and (2) a reinforcement structure. The reinforcement structure may comprise any of mesh, fabric and/or tape. The reinforcement structure preferably comprises an inorganic fabric, and may be installed by application of a suitable adhesive binder.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: September 15, 2015
    Assignee: SHERWIN-WILLIAMS PROTECTIVE & MARINE COATINGS
    Inventors: John Darryl Green, William Allen, Andrew Philip Taylor
  • Publication number: 20150111857
    Abstract: Compounds and compositions useful for treating disorders related to KIT and PDFGR are described herein.
    Type: Application
    Filed: October 17, 2014
    Publication date: April 23, 2015
    Applicant: BLUEPRINT MEDICINES CORPORATION
    Inventors: Brian L. Hodous, Joseph L. Kim, Chandrasekhar V. Miduturu, Douglas Wilson, Yulian Zhang
  • Publication number: 20140353551
    Abstract: The invention relates to dispersants for inorganic particles, preferably for hydraulic binders, which comprises the following structural units: i) at least one triazine structural unit, ii) at least one polyalkylene glycol structural unit, iii) and at least two phosphoric ester structural units, and also relates to a process for preparing the dispersants, to building material mixtures comprising one or more dispersants and one or more inorganic binders. The invention relates to the use of the dispersants as a water reducing agent, as a means for reducing the viscosity and for enhancing the early strengths of aqueous inorganic binders, and also to the use as a grinding aid in the production of cement.
    Type: Application
    Filed: December 7, 2012
    Publication date: December 4, 2014
    Applicant: Construction Research & Technology GmbH
    Inventors: Joachim Dengler, Alexander Kraus
  • Patent number: 8877838
    Abstract: The present invention relates to flame retardant polymer compositions which comprise melamine phenylphosphinates and mixtures with dihydro-oxa-phosphaphenanthrene derivatives. The compositions are especially useful for the manufacture of flame retardant compounds based on polyfunctional epoxides or polycondensates like polyesters, polyamides and polycarbonates.
    Type: Grant
    Filed: November 16, 2009
    Date of Patent: November 4, 2014
    Assignee: BASF SE
    Inventors: Sabine Fuchs, Thomas Weiβ
  • Patent number: 8865321
    Abstract: The present invention relates to electronic devices, in particular organic electroluminescent devices, which comprise compounds of the formula (1), and to the corresponding compounds and to the use thereof in organic electroluminescent devices.
    Type: Grant
    Filed: October 15, 2009
    Date of Patent: October 21, 2014
    Assignee: Merck Patent GmbH
    Inventors: Philipp Stoessel, Holger Heil, Dominik Joosten, Christof Pflumm, Anja Gerhard, Esther Breuning, Amir Hossain Parham
  • Patent number: 8697864
    Abstract: Flame retardant compositions that are halogen-free or substantially halogen-free are disclosed. In certain examples, the compositions comprise a halogen-free or substantially halogen-free epoxide and one or more phosphorated compounds. In some examples, the phosphorated compound comprises an average particle size less than 10 microns. In other examples, the phosphorated compound provides a surface area of 78.5 ?m2 to about 1965 ?m2. Prepregs, laminates, molded articles and printed circuit boards using the compositions are also disclosed.
    Type: Grant
    Filed: March 5, 2012
    Date of Patent: April 15, 2014
    Assignee: Isola USA Corp.
    Inventors: David Bedner, William D. Varnell
  • Publication number: 20140066406
    Abstract: The invention features compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 6, 2014
    Applicant: ARIAD PHARMACEUTICALS, INC.
    Inventor: ARIAD PHARMACEUTICALS, INC.
  • Publication number: 20130338264
    Abstract: Condensation products of melamine and phenylphosphonic acid, a process for their preparation, their compositions with polymeric materials and their use as flame retardants in polymer substrates are provided. The compositions are especially useful for the manufacture of flame retardant compounds based on polyfunctional epoxides or polycondensates, such as polyesters, polyamides and polycarbonates.
    Type: Application
    Filed: March 9, 2012
    Publication date: December 19, 2013
    Applicant: BASF SE
    Inventors: Thomas Weiss, Beat Michael Aebli, Rainer Xalter
  • Publication number: 20130294994
    Abstract: A producing method of a high-purity pyrophosphate comprising a calcination of the orthophosphate under the condition of 120° C.-350° C.; and a producing method suitable for manufacturing effectively the high-purity melamine pyrophosphate.
    Type: Application
    Filed: August 25, 2011
    Publication date: November 7, 2013
    Applicant: ADEKA CORPORATION
    Inventors: Tetsuo Kamimoto, Takayoshi Kaneda, Hitoshi Kinoshita, Shinji Nakano, Susumu Ishii
  • Publication number: 20130225527
    Abstract: The invention features compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 29, 2013
    Applicant: ARIAD PHARMACEUTICALS, INC.
    Inventor: ARIAD PHARMACEUTICALS, INC.
  • Publication number: 20120292582
    Abstract: The invention relates to ammonium salts of 9,10-dihydro-10-hydroxy-9-oxa-10-phosphaphenanthrene-10-one or -10-oxide (DOPO-OH) of formula I: wherein X is selected from ammonia, melamine, and guanidine, as well as ring-opened hydrolyzates thereof according to the following formula II: wherein X is defined as above.
    Type: Application
    Filed: April 17, 2012
    Publication date: November 22, 2012
    Applicant: Krems Chemie Chemical Services AG
    Inventors: Thomas Zich, Fritz Freidl, Bernadette Mehofer, Michael Hönel, Johannes Artner, Manfred Döring, Michael Ciesielski
  • Publication number: 20120202776
    Abstract: The invention features compounds of the general formula (I) in which the variable groups are as defined herein, and to their preparation and use.
    Type: Application
    Filed: May 21, 2009
    Publication date: August 9, 2012
    Applicant: ARIAD Pharmaceuticals, Inc.
    Inventors: Yihan Wang, Wei-Sheng Huang, Shuangying Liu, William C. Shakespeare, R. Mathew Thomas, Jiwei Qi, Feng Li, Xiaotian Zhu, Anna Kohlmann, David C. Dalgarno, Jan Antoinette C. Romero, Dong Zou
  • Patent number: 8153787
    Abstract: The present invention provides 5-azacytosine derivatives with antiviral activity, specifically having viral replication inhibiting properties, more particularly in DNA viruses such as pox-, papilloma- and herpes viruses in humans. The invention also provides pharmaceutical compositions comprising such 5-azacytosine derivatives as active ingredients in combination with pharmaceutically acceptable carriers, which are useful for the treatment of subjects suffering from viral infections.
    Type: Grant
    Filed: December 8, 2006
    Date of Patent: April 10, 2012
    Assignees: K.U. Leuven Research & Development, Institute of Organic Chemistry and Biochemistry Academy of Sciences of the Czech Republic
    Inventors: Antonin Holy, Marcela Krecmerova, Alois Piskala, Graciela Andrei, Robert Snoeck, Erik De Clercq, Johan Neyts, Lieve Naesens
  • Publication number: 20110309345
    Abstract: The present invention provides a compound of formula (I) for an organic electroluminescent device: wherein X and Y are each independently selected for the group consisting of an alkyl substituted, aryl substituted or unsubstituted carbazole, indolocarbazole, triphenylsilyl and diphenylphosphine oxide represented by formula (A), (B), (C), (D) or (E), in which R1, R2, and R3 are each independently selected from the group consisting of a hydrogen, an alkyl having 1 to 15 carbons atoms, an aryl group having 6 to 15 carbons atoms, an alkyl substituted, an aryl substituted or unsubstituted triphenylsilyl, and a diphenylphosphine oxide represented by the formula (D) or (E); m and n are each independently 0 or 1, provided that m+n is 1 or more; and Ar1 and Ar2 are each independently selected from the group consisting of an alkyl substituted, aryl substituted or unsubstituted phenyl, tolyl, naphthyl, fluorenyl, anthracenyl, and phenanthryl.
    Type: Application
    Filed: June 16, 2011
    Publication date: December 22, 2011
    Applicant: E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD.
    Inventors: Banumathy Balaganesan, Yi-Huan Fu, Huang-Ming Guo
  • Publication number: 20110288206
    Abstract: The present invention relates to flame retardant polymer compositions which comprise melamine phenylphosphinates and mixtures with dihydro-oxa-phosphaphenanthrene derivatives. The compositions are especially useful for the manufacture of flame retardant compounds based on polyfunctional epoxides or polycondensates like polyesters, polyamides and polycarbonates.
    Type: Application
    Filed: November 16, 2009
    Publication date: November 24, 2011
    Applicant: BASF SE
    Inventors: Sabine Fuchs, Thomas Weiss
  • Publication number: 20110245383
    Abstract: The present invention relates to phosphorus-containing triazine compounds of the formula (I) and (III) and to the polymers obtainable from the water-eliminating polycondensation of a compound of the formula (II), and to the use thereof as flame retardants. [(A-H)+]m[Mm+(HPO42?)m]??(III-1), [(A-H)+]m[Mm+(P2O74?)m/2]??(III-2).
    Type: Application
    Filed: July 16, 2008
    Publication date: October 6, 2011
    Inventors: Trupti Dave, Wolfgang Wehner
  • Publication number: 20110201778
    Abstract: The present invention relates to electronic devices, in particular organic electroluminescent devices, which comprise compounds of the formula (1), and to the corresponding compounds and to the use thereof in organic electroluminescent devices.
    Type: Application
    Filed: October 15, 2009
    Publication date: August 18, 2011
    Applicant: Merck Patent GmbH
    Inventors: Philipp Stoessel, Holger Heil, Dominik Joosten, Christof Pflumm, Anja Gerhard, Esther Breuning, Amir Hossain
  • Patent number: 7888504
    Abstract: Compounds are provided which are glucokinase activators and thus are useful in treating diabetes and related diseases and have the structure wherein in the ring represents one or two double bonds; R1 is aryl or heteroaryl; R2 is halogen, cycloalkyl, heterocyclyl, aryl, or heteroaryl; R5 is as defined herein; Z is O, S, S(O), S(O)2, or NR5a; X is S, O, N, NR3, or CR3; Y is NCR4 or N4; R3, R4, and R5 are as defined herein; R8 is aryl or heteroaryl; R6 and R7 are independently H, halogen, or alkyl; m is 0 or 1; and n is 0 to 3, or a pharmaceutically acceptable salt thereof. A method for treating diabetes and related diseases employing the above compounds is also provided.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: February 15, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Sean Chen, Peter T. W. Cheng, Rebecca A. Smirk
  • Publication number: 20100210594
    Abstract: The present invention relates to substituted arylsulphonylaminomethyl-phosphonic acid derivatives of general formula wherein R, X, Y and Z are defined as in claim 1, the tautomers, enantiomers, diastereomers, mixtures thereof and salts thereof which have valuable pharmacological properties, particularly the suppression of the interaction of glycogen phosphorylase a with the GL subunit of glycogen-associated protein phosphatase 1 (PP1), and their use as pharmaceutical compositions.
    Type: Application
    Filed: July 25, 2008
    Publication date: August 19, 2010
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Holger Wagner, Elke Langkopf, Matthias Eckhardt, Ruediger Streicher, Corinna Schoelch, Annette Schuler-Metz, Alexander Pautsch
  • Patent number: 7687480
    Abstract: The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and the like.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: March 30, 2010
    Assignee: The Regents of the University of California
    Inventors: Karl Y. Hostetler, James R. Beadle, Ganesh D. Kini
  • Publication number: 20090264339
    Abstract: This invention relates to heterocyclic compounds of the formulas shown in the specification. It also relates to methods for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, and tissue injuries with one of the heterocyclic compounds.
    Type: Application
    Filed: November 3, 2008
    Publication date: October 22, 2009
    Applicant: TaiGen Biotechnology Co., Ltd.
    Inventors: Chi-Feng Yen, Cheng-Kung Hu, Chang-Pin Huang, Ying-Huey Huang, Gholam Hossein Hakimelahi, Chi-Hsin Richard King
  • Publication number: 20090005346
    Abstract: The present invention provides 5-azacytosine derivatives with antiviral activity, specifically having viral replication inhibiting properties, more particularly in DNA viruses such as pox-, papilloma- and herpes viruses in humans. The invention also provides pharmaceutical compositions comprising such 5-azacytosine derivatives as active ingredients in combination with pharmaceutically acceptable carriers, which are useful for the treatment of subjects suffering from viral infections.
    Type: Application
    Filed: December 8, 2006
    Publication date: January 1, 2009
    Applicants: K.U.Leuven Research & Development, Institute of Organic Chemistry and Biochemistry Academy of Sciences of the Czech Republic
    Inventors: Antonin Holy, Marcela Krecmerova, Alois Piskala, Graciela Andrei, Erik De Clercq, Robert Snoeck, Johan Neyts, Lieve Naesens
  • Publication number: 20080255353
    Abstract: A method for producing a melamine salt of bis(pentaerythritol phosphate) phosphoric acid is proposed. The method includes the steps of reacting and mixing pentaerythritol and diphosphorous pentaoxide in an extruder to carry out esterification to produce bis(pentaerythritol phosphate) phosphoric acid; and mixing bis(pentaerythritol phosphate) phosphoric acid with melamine or a derivative thereof to carry out quaternization in the presence of a solvent, followed by removing water to obtain a melamine salt of bis(pentaerythritol phosphate) phosphoric acid. Diphosphorous pentaoxide is used in the method as a reactant, so that no hydrogen chloride is produced and it is not necessary to recollect trichlorophosphoric acid. Moreover, in the method of the present invention, such that esterification time can be shortened and a high pressure in a closed reaction system that causes explosion can be avoided.
    Type: Application
    Filed: January 25, 2008
    Publication date: October 16, 2008
    Applicant: Chang Chun Plastics Co., Ltd.
    Inventors: Kuen-Yuan HWANG, An-Pang Tu, Gai-Chi Chen
  • Patent number: 7345168
    Abstract: A simple and economical process for the preparation of polyphosphates of organic bases consists of reacting a mixture of phosphorus pentoxide and at least one organic nitrogen base with at least one compound which releases water accompanied by decomposition under the prevailing conditions in such a molar ratio that upon decomposition of the water-releasing compound at most essentially 2 mol. water are produced per mol. phosphorus pentoxide. Thus-prepared polyphosphates are particularly suitable as flame-protection agents for plastics.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: March 18, 2008
    Assignee: Chemische Fabrik Budenheim KG
    Inventors: Liselotte Götzmann, legal representative, Hans-Dieter Nagerl, Thomas Futterer, Karl Gotzmann
  • Patent number: 7250509
    Abstract: A method for preparing a melamine salt of pentaerypolyol phosphoric acid is provided. The method comprises the following steps of: ball milling a mixture of pentaerypolyol and phosphorus pentoxide (P2O5) under a solvent-free reacting environment to obtain a pentaerypolyol phosphoric acid, and ball milling a mixture of a pentaerypolyol phosphoric acid and melamine without organic solvent reacting environment to obtain a melamine salt of pentaerypolyol phosphoric acid.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: July 31, 2007
    Assignee: Chung Shan Institute of Science and Technology
    Inventors: Yu-Sheng Lin, Wen-Chiung Su, Chong Ma, Yuen-Hsin Peng
  • Patent number: 6797821
    Abstract: The present invention discloses an active-hydrogen-containing phosphorus compound for cross-linking a resin and for imparting flame-retardancy to the cured resin, and in particular to a cured frame-retardant epoxy resin prepared by reacting the hardener with a di- or poly-functional epoxy resin via an addition reaction between the active hydrogen and the epoxide group. The present invention also discloses an epoxy resin made from the active-hydrogen-containing phosphorus compound and epihalohydrin.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: September 28, 2004
    Inventors: Chun-Shan Wang, Jeng-Yueh Shieh, Ching Hsuan Lin
  • Patent number: 6737526
    Abstract: Bis-(pentaerythritol phosphate) phosphoric acid is prepared by mechanochemical synthesis including ball milling a mixture containing P2O5, pentaerythritol, an alkyl benzene having one or two C1-C5 alkyl groups, and a metal halide catalyst, in a ball mill as a reactor and at a temperature of room temperature to 150° C. Melamine is then reacted with the resulting bis-(pentaerythritol phosphate) phosphoric acid to form a product of melamine salt thereof.
    Type: Grant
    Filed: November 26, 2002
    Date of Patent: May 18, 2004
    Assignee: Chung-Shan Institute of Science & Technology
    Inventors: Chong Ma, Tseng-Rong Wu, Yuen-Hsin Peng
  • Patent number: 6673924
    Abstract: The present invention includes a precursor compound pertaining to a 1,2,4-Triazolo[4,3-a][1,3,5] Triazine compound, particularly a 1,2,4-Triazolo[4,3-a][1,3,5] Triazine-3,5,7-Triamine, and novel fused ring structures such as triazolyl-tetrazinyl-aminotriazine compounds, and complexes and salts thereof, and other such chemical structures.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: January 6, 2004
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: William M. Koppes, Michael E. Sitzmann
  • Patent number: 6653474
    Abstract: Salt of a 1,3,5-triazine compound with polyphosphoric acid with a virtually linear structure, with the number average degree of condensation n being higher than 20, the content of the 1,3,5-triazine compound being higher than 1.1 mole per mole of phosphorus atom and the pH of a 10% slurry in water being higher than 4.5. Further, a process for the preparation of the polyphosphate salt of a 1,3,5-triazine compound with a number average degree of condensation n that is higher than 20, by converting a 1,3,5-triazine compound with orthophosphoric acid at room temperature into the phosphate of the 1,3,5-triazine compound, after which this salt is converted at elevated temperature into a polyphosphate of the 1,3,5-triazine compound, and further flame retardant polymer compositions comprising the polyphosphate salt of a 1,3,5-triazine compound with a number average degree of condensation n higher than 20.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: November 25, 2003
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Johanna G. Kersjes, Renier H. M. Kierkels
  • Patent number: 6518453
    Abstract: In a process for stabilizing chemical compounds having at least one ethylenically unsaturated bond to undesired free radical polymerization, a nitroxyl radical and a chemical compound containing phosphorus in chemically bonded form are added to the unsaturated compound present as pure substance or as a component of a mixture.
    Type: Grant
    Filed: July 3, 2001
    Date of Patent: February 11, 2003
    Assignee: BASF Aktiengesellschaft
    Inventors: Heinz Friedrich Sutoris, Gerhard Wagenblast, Volker Schliephake, Jürgen Schröder, Klaus Joachim Müller-Engel, Harald Keller, Thomas Jaworek
  • Publication number: 20030008848
    Abstract: Compound of the formula I, II, III or IV 1
    Type: Application
    Filed: December 5, 2001
    Publication date: January 9, 2003
    Inventors: Roman Wolfgang Fleck, Terence Alfred Kelly, Jin Mi Kim, Jinbo Lee, Rene Marc Lemieux, Ronald John Sorcek, Jiang-Ping Wu
  • Patent number: 6489333
    Abstract: This invention relates to novel heterocycles which are useful as antagonists of the &agr;v&bgr;3 integrin, the &agr;2b&bgr;3 integrin, and related cell surface adhesive protein receptors, to pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of cell adhesion, the treatment of angiogenic disorders, inflammation, bone degradation, cancer metastasis, diabetic retinopathy, thrombosis, restenosis, macular degeneration, and other conditions mediated by cell adhesion and/or cell migration and/or angiogenesis.
    Type: Grant
    Filed: April 9, 2001
    Date of Patent: December 3, 2002
    Assignee: Bristol - Meyers Squibb Pharma Company
    Inventors: William J. Pitts, Prabhakar K. Jadhav
  • Publication number: 20020052495
    Abstract: Carboxylic acid derivatives 1
    Type: Application
    Filed: December 27, 2000
    Publication date: May 2, 2002
    Inventors: Hartmut Riechers, Dagmar Klinge, Wilhelm Amberg, Andreas Kling, Stefan Muller, Ernst Baumann, Joachim Rheinheimer, Uwe Josef Vogelbacher, Wolfgang Wernet, Liliane Unger, Manfred Raschack
  • Patent number: 6369137
    Abstract: Salt of a 1,3,5-triazine compound with polyphosphoric acid with a virtually linear structure, with the number average degree of condensation n being higher than 20, the content of the 1,3,5-triazine compound being higher than 1.1 mole per mole of phosphorus atom and the pH of a 10% slurry in water being higher than 4.5. Further, a process for the preparation of the polyphosphate salt of a 1,3,5-triazine compound with a number average degree of condensation n that is higher than 20, by converting a 1,3,5-triazine compound with orthophosphoric acid at room temperature into the phosphate of the 1,3,5-triazine compound, after which this salt is converted at elevated temperature into a polyphosphate of the 1,3,5-triazine compound, and further flame retardant polymer compositions comprising the polyphosphate salt of a 1,3,5-triazine compound with a number average degree of condensation n higher than 20.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: April 9, 2002
    Assignee: DSM N.V.
    Inventors: Johanna G. Kersjes, Renier H. M. Kierkels
  • Publication number: 20010051720
    Abstract: The present invention describes 1,3,5-Triazine-2,4,6-tris-hydroxyalkyl acids of the general formula I 1
    Type: Application
    Filed: July 12, 2001
    Publication date: December 13, 2001
    Inventor: John J. Waldmann
  • Patent number: 6268494
    Abstract: This invention relates to a novel process for the preparation of condensed melamine phosphates, and to melamine pyrophosphate prepared by this process having improved thermal stability as a flame retardant.
    Type: Grant
    Filed: August 9, 2000
    Date of Patent: July 31, 2001
    Assignee: E. I. du Pont de Nemours and Company
    Inventor: Robert Valentine Kasowski
  • Publication number: 20010005745
    Abstract: Salt of a 1,3,5-triazine compound with polyphosphoric acid with a virtually linear structure, with the number average degree of condensation n being higher than 20, the content of the 1,3,5-triazine compound being higher than 1.1 mole per mole of phosphorus atom and the pH of a 10% slurry in water being higher than 4.5. Further, a process for the preparation of the polyphosphate salt of a 1,3,5-triazine compound with a number average degree of condensation n that is higher than 20, by converting a 1,3,5-triazine compound with orthophosphoric acid at room temperature into the phosphate of the 1,3,5-triazine compound, after which this salt is converted at elevated temperature into a polyphosphate of the 1,3,5-triazine compound, and further flame retardant polymer compositions comprising the polyphosphate salt of a 1,3,5-triazine compound with a number average degree of condensation n higher than 20.
    Type: Application
    Filed: January 8, 2001
    Publication date: June 28, 2001
    Inventors: Johanna G. Kersjes, Renier H.M. Kierkels
  • Patent number: 6194576
    Abstract: Nucleotide analogues having the general formula (I) and pharmaceutically acceptable derivatives: wherein n is 0 or an integer; X is O or S, CH2, CH-halogen, CH—N3, or C═CH2; Q and U are independently selected from: O, S, and CH(Ra) wherein Ra is hydrogen, OH, halogen, N3 ,NH2, SH, carboxyl, C1-6 alkyl or Ra is CH2(Rb) wherein Rb is hydrogen, OH, SH, NH2, C1-6 alkyl or carboxyl; or both Q and U are CH when Q and U are linked by a double bond; Z is selected from: O, a C1-6 alkoxy, a C1-6 thioalkyl, a C1-6 aminoalkyl, (CH2)m wherein m is 0 or an integer, and N(Rc)2 wherein both Rc are independently hydrogen or a C1-6 alkyl; and R2 is a purine or pyrimidine base or an analogue or derivative thereof. Members of this series of analogues possess anti-viral activity.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: February 27, 2001
    Assignee: BioChem Pharma, Inc.
    Inventors: Nghe Nguyen-Ba, Miguel Quimpere, Laval Chan Chun Kong, William L. Brown, Gervais Dionne
  • Patent number: 6136973
    Abstract: A melamine.melam.melem salt of a polyphosphoric acid, which has a solubility of from 0.01 to 0.10 g/100 ml in water (25.degree. C.), a pH of from 4.0 to 7.0 as a 10 wt % aqueous slurry (25.degree. C.), and a melamine content of from 0.05 to 1.00 mol, a melam content of from 0.30 to 0.60 mol and a melem content of from 0.05 to 0.80 mol, per mol of the phosphorous atom; andA process for producing the above mentioned melamine.melam.melem salt of a polyphosphoric acid, which comprises the following steps (a) and (b):(a) a step of obtaining a reaction product by mixing melamine and phosphoric acid at a temperature of from 0 to 330.degree. C. in such a ratio that the melamine is from 2.0 to 4.0 mols per mol of the phosphoric acid (as calculated as orthophosphoric acid content), and(b) a step of baking the reaction product obtained in step (a) at a temperature of from 340 to 450.degree. C. for from 0.1 to 30 hours.
    Type: Grant
    Filed: September 2, 1999
    Date of Patent: October 24, 2000
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Keitaro Suzuki, Masuo Shindo, Motoko Iijima
  • Patent number: 6121445
    Abstract: A 1,3,5-triazine derivative salt of a polyacid comprising phosphorus, sulfur and oxygen, which has a solubility of from 0.01 to 0.10 g/100 ml in water (25.degree. C.) and a pH of from 2.0 to 7.0 as a 10 wt % aqueous slurry (25.degree. C.), and which is obtained from the following steps (a) and (b):(a) a step of obtaining a reaction product by mixing melamine, phosphoric acid and sulfuric acid at a temperature of from 0 to 330.degree. C. in such ratios that the melamine is from 1.0 to 4.0 mols per mol of the total molar amount of the phosphoric acid (as calculated as orthophosphoric acid content) and the sulfuric acid (as sulfuric acid content), and the sulfuric acid (as sulfuric acid content) is from 0.05 to 20 mols per mol of the phosphoric acid (as calculated as orthophosphoric acid content), and(b) a step of baking the reaction product obtained in step (a) at a temperature of from 340 to 400.degree. C. for from 0.1 to 30 hours; and a process for its production.
    Type: Grant
    Filed: September 3, 1999
    Date of Patent: September 19, 2000
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Keitaro Suzuki, Masuo Shindo, Motoko Iijima
  • Patent number: 6114421
    Abstract: Flame-retarding composition for polymers, copolymers and mixed polymers comprising piperazine diacid pyrophosphate, piperazine acid phosphate, melamine acid phosphate, melamine and possibly though not necessarily, an alkaline phosphate. Process for the preparation of said flame-retarding composition, consisting in reacting a mixture comprising phosphoric anhydride, piperazine and melamine with water in controlled conditions, either with mass reaction or suspension reaction with a suitable solvent/dispersing agent.
    Type: Grant
    Filed: July 2, 1998
    Date of Patent: September 5, 2000
    Assignee: Domus Industria Chimica S.p.A,
    Inventor: Alessandro Malcangi
  • Patent number: 6008349
    Abstract: A melamine polymetaphosphate having a solubility of from 0.01 to 0.10 g/100 ml in water at 25.degree. C., a pH of from 2.5 to 4.5 in the form of a 10 wt % aqueous slurry at 25.degree. C. and a melamine content of from 1.0 to 1.1 mol per mol of phosphorus atom.A process for producing such a melamine polymetaphosphate, which comprises the following steps (a) and (b):(a) a step of mixing melamine, urea and an aqueous orthophosphoric acid solution containing at least 40 wt % of orthophosphoric acid, in such a ratio that melamine is from 1.0 to 1.5 mol per mol of orthophosphoric acid and urea is from 0.1 to 1.5 mol per mol of orthophosphoric acid, at a temperature of from 0 to 140.degree. C., to form a reaction mixture, and stirring the reaction mixture at a temperature of from 0 to 140.degree. C., while removing water, to obtain a powdery product of a double salt of orthophosphoric acid with melamine and urea; and(b) a step of calcining the powdery product obtained in step (a) at a temperature of from 240 to 340.
    Type: Grant
    Filed: June 10, 1998
    Date of Patent: December 28, 1999
    Assignee: Nissan Chemical Industries, Ltd.
    Inventors: Keitaro Suzuki, Kouji Shishido, Masuo Shindo
  • Patent number: 5886179
    Abstract: Nucleotide phosphonate esters characterized by the presence of an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise an ester bond that is hydrolyzed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for their synthesis and use are described.
    Type: Grant
    Filed: December 29, 1995
    Date of Patent: March 23, 1999
    Assignee: Gilead Sciences, Inc.
    Inventors: Murty N. Arimilli, Norbert W. Bischofberger, Robert J. Jones, William A. Lee, Ernest J. Prisbe
  • Patent number: 5804583
    Abstract: Derivatives of bicyclic heterocycles comprising a pyrimidone ring fused to another 5, 6, or 7 membered nitrogen heterocycle which is C-substituted, through a methylene bridge, by a biphenyl group.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: September 8, 1998
    Assignee: Istituto Luso Farmaco D'Italia
    Inventors: Aldo Salimbeni, Davide Poma, Anna Renzetti, Carlo Scolastico
  • Patent number: 5744600
    Abstract: A compound of the Formula I or Formula II ##STR1## wherein R.sup.1 and R.sup.2 are independently hydrogen, hydroxy, chlorine, fluorine, bromine, or an organic substituent having 1 to 5 carbon atoms and selected from acyloxy having a hydrocarbon stem of 1 to 4 carbon atoms, alkoxy, alkylthio, amino, alkylamino and dialkylamino;R.sup.3 and R.sup.4 are independently hydrogen, or organic phosphonic ester substituents having 1 to 12 carbon atoms and selected from alkyl, alkenyl, aryl, and aralkyl; andB is a heterocyclic group selected from the group consisting of pyrimidine, purine, triazine, deazapurine, and triazole, attached through a ring nitrogen atom thereof optionally substituted with 1 to 3 substituents selected from the group consisting of hydroxy, mercapto, amino, hydrazino, fluoro, chloro, bromo, iodo, C.sub.1 to C.sub.3 alkyl, C2-C3 alkenyl, C2-C3 haloalkenyl, C1-C3 alkoxy, and C1-C3 alkylthio;and the pharmaceutically acceptable acid addition, metal, and amine salts thereof.
    Type: Grant
    Filed: December 16, 1994
    Date of Patent: April 28, 1998
    Assignees: Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic, Rega Stichting v.z.w.
    Inventors: Muzammil M. Mansuri, John C. Martin, Thomas W. Hudyma, Joanne J. Bronson, Louis M. Ferrara
  • Patent number: 5677450
    Abstract: Disclosed are an organic acid salt of melamine represented by the following general formula (1) and a thermosetting and a photocurable and thermosetting coating compositions containing the salt mentioned above. ##STR1## wherein Z represents ##STR2## wherein R.sup.1 represents a hydrogen atom or an alkyl group, alkylene group, alicyclic hydrocarbon, or aromatic hydrocarbon severally having from 1 to 18 carbon atoms, or any of said groups or hydrocarbons whose hydrogen atom is substituted by carboxyl group, hydroxyl group, or a halogen atom, R.sup.2 represents a hydrogen atom or an alkyl group or alkylene group severally having from 1 to 9 carbon atoms, or any of said groups whose hydrogen atom is substituted by acryloyl group or methacryloyl group, R.sup.3 represents an alkyl group or alkylene group severally having from 1 to 9 carbon atoms, or any of said groups whose hydrogen atom is substituted by acryloyl group or methacryloyl group, and R.sup.
    Type: Grant
    Filed: November 5, 1996
    Date of Patent: October 14, 1997
    Assignee: Taiyo Ink Manufacturing Co., Ltd.
    Inventors: Nobuyuki Suzuki, Kazunobu Fukushima, Kyo Ichikawa, Teruo Saito, Hitoshi Inagaki
  • Patent number: 5571915
    Abstract: This invention provides a process for preparing amide derivatives of acids by the reaction of haloaminotriazines and acid halides.This invention also provides a process for preparing isocyanates and isocyanate adducts from amide derivatives derived from haloaminotriazines and acid halides such as oxalyl chloride, phosgene and phosgene analogs.Melamine derived acid amides are prepared by reaction of trichloro and hexachloromelamines with chloroformates and acid chlorides. The by-product chlorine may be recycled in this process.Amides, carbamates, sulfonamides, phosphoramides, and related amide derivatives may be prepared by the novel processes of the invention.
    Type: Grant
    Filed: March 3, 1995
    Date of Patent: November 5, 1996
    Assignee: Cytec Technology Corp.
    Inventor: Ram B. Gupta