Additional Ring Containing Patents (Class 544/206)
  • Patent number: 6288226
    Abstract: Provided is a process for preparing an at least bis-carbamate functional 1,3,5-triazine by contacting an at least diamino-1,3,5-triazine, an acyclic organic carbonate and a base, as well as certain novel compositions producible thereby. Also provided are substantially halogen contamination free crosslinker compositions comprising the products obtainable by the process, and curable compositions based upon these crosslinkers.
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: September 11, 2001
    Assignee: Cytec Technology Corporation
    Inventors: Lawrence A. Flood, Ram B. Gupta, Revathi Iyengar, David A. Ley, Venkatarao K. Pai
  • Patent number: 6284710
    Abstract: The invention relates to novel substituted 2-amino-4-alkylamino-1,3,5-triazines of the formula (I) in which R1 represents optionally substituted methyl, R2 represents hydrogen or alkyl, Y represents in each case optionally substituted benzyl, naphthylmethyl, heterocyclylmethyl or heterocyclyloxy, and Z represents hydrogen, represents halogen or represents in each case optionally substituted alkyl, alkoxy, alkylcarboxyl, alkoxycarbonyl, alkylthio, alkylsulphinyl, alkylsulphonyl, alkenyl or alkinyl, to processes and to novel intermediates for their preparation and to their use as herbicides.
    Type: Grant
    Filed: April 6, 1999
    Date of Patent: September 4, 2001
    Assignees: Bayer Aktiengesellschaft, Nihon Bayer Agrochem K.L.
    Inventors: Hans-Jochem Riebel, Stefan Lehr, Uwe Stelzer, Yukiyoshi Watanabe, Markus Dollinger, Peter Dahmen, Seishi Ito, Toshio Goto, Akihiko Yanagi
  • Patent number: 6271178
    Abstract: The invention relates to novel substituted 2,4-diamino-1,3,5-triazines of the formula (I) In which R1 represents hydrogen or optionally substitued alkyl, R2 represents formyl or represents in each case optionally substituted alkylcarbonyl, alkoxycarbonyl, alkylsulphonyl, arylcarbonyl or arylsulphonyl, R3 represents in each case optionally substituted alkyl or cycloalkyl, R4 represents hydrogen or alkyl, A represents oxygen or methylene, Ar represents in each case optionally substituted aryl or heterocyclyl, and z represents hydrogen, hydroxyl, cyano, nitrogen, halogen or represents in each case optionally substituted alkyl, alkoxy, alkylcarbonyl, alkoxycarbonyl, alkylthio, alkylsulphinyl, alkylsulphonyl, alkenyl or alkinyl, (except for three prior-art compounds), to processes and to novel intermediates for preparation of the novel compounds and to their use as herbicides.
    Type: Grant
    Filed: April 7, 1999
    Date of Patent: August 7, 2001
    Assignees: Bayer AG, Nihon Bayer Agrochem K.K.
    Inventors: Hans-Jochem Riebel, Stefan Lehr, Uwe Stelzer, Yukiyoshi Watanabe, Markus Dollinger, Toshio Goto
  • Patent number: 6265348
    Abstract: Compounds of the formula (I) and salts thereof in which R1 to R6, W, X, Y and Z are defined as in claim 1, have herbicidal or plant growth-regulatory properties. They can be prepared by processes analogous to known processes (cf. claim 5), in some cases via novel intermediate products (cf.
    Type: Grant
    Filed: February 17, 1999
    Date of Patent: July 24, 2001
    Assignee: Hoechst Schering AgrEvo GmbH
    Inventors: Heinz Kehne, Lothar Willms, Klaus Bauer, Hermann Bieringer, Christopher Rosinger
  • Patent number: 6204382
    Abstract: The present invention relates generally to carboxylated amino-1,3,5-triazines and the preparation thereof via carboxylation of amino-1,3,5-triazines with carbon dioxide and a base. These carboxylated amino-1,3,5-triazines find use, for example, as intermediates in the production of other useful amino-1,3,5-triazine derivatives, and particularly carbamate and isocyanate functional 1,3,5-triazines. The present invention also relates to the preparation of such carbamate and isocyanate functional 1,3,5-triazines.
    Type: Grant
    Filed: August 5, 1994
    Date of Patent: March 20, 2001
    Assignee: Cytec Technology Corp.
    Inventors: Lawrence Allen Flood, Ram Baboo Gupta
  • Patent number: 6191131
    Abstract: Corticotropin releasing factor (CRF) antagonists of formula I or II: and their use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or heart-related diseases and colonic hypersensitivity associated with psychopathological disturbance and stress.
    Type: Grant
    Filed: January 28, 1998
    Date of Patent: February 20, 2001
    Assignee: DuPont Pharmaceuticals Company
    Inventors: Liqi He, Paul Gilligan, Robert Chorvat, Argyrios Georgios Arvanitis
  • Patent number: 6150362
    Abstract: Compounds having Formula I ##STR1## or pharmaceutically acceptable salts or prodrugs thereof, are useful for treating pathological states which arise from or are exacerbated by angiogenesis. The invention also relates to pharmaceutical compositions comprising these compounds and to methods of inhibiting anglogenesis in a mammal.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: November 21, 2000
    Inventors: Jack Henkin, Donald J. Davidson
  • Patent number: 6143888
    Abstract: The present invention provides a process for the inhibition (quenching) of the effect of an anionic fluorescent whitening agents on a substrate, comprising treating the substrate with a triazine UVA compound, some of which are new compounds.
    Type: Grant
    Filed: December 2, 1998
    Date of Patent: November 7, 2000
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Peter Rohringer, Dieter Reinehr, Robert Hochberg, Georges Metzger
  • Patent number: 6111102
    Abstract: Compounds of the formula I or salts thereof, in whichX is oxygen, --O--NR.sup.2 -- or --SO.sub.2 --NR.sup.2 --, and Y is N or CH,R.sup.1 is (C.sub.1 -C.sub.6)alkyl, (C.sub.2 -C.sub.6)alkenyl or (C.sub.2 -C.sub.6)alkynyl, which are in each case optionally substituted, or, in the case where X=oxygen, also (subst.) phenyl,R.sup.2 is H, (C.sub.1 -C.sub.6)alkyl, (C.sub.2 -C.sub.6)alkenyl or -alkynyl or (C.sub.3 -C.sub.6)cycloalkyl,R.sup.3 and R.sup.4 are H, (subst.) (C.sub.1 -C.sub.4)alkyl or (subst.) (C.sub.1 -C.sub.4)alkoxy or halogen, (C.sub.1 -C.sub.4)alkylthio, (C.sub.1 -C.sub.4)-alkylamino or di[(C.sub.1 -C.sub.4)alkyl]-amino,R.sup.5 is H or (C.sub.1 -C.sub.4)alkyl and R.sup.6 is hydrogen,may be prepared by reacting compounds of the formula II,R.sup.1 --X--R.sup.7 (II)with compounds of the formulae III, IV and VR.sup.8 --OCN (III)SO.sub.2 Cl.sub.2 (IV) ##STR1## where R.sup.7 and R.sup.8 are H, a quarternary ammonium ion or one equivalent of a metal cation.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: August 29, 2000
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Gunter Schlegel
  • Patent number: 6071860
    Abstract: Compounds of the formula (I) and salts thereof ##STR1## where R.sup.1 to R.sup.5, A, Z, X, X', n and m are as defined in claim 1 are suitable as herbicides and plant growth regulators.
    Type: Grant
    Filed: February 6, 1997
    Date of Patent: June 6, 2000
    Assignee: Hoechst Schering AgrEvo GmbH
    Inventors: Wolfgang Giencke, Lothar Willms, Klaus Bauer, Hermann Bieringer, Christopher Rosinger
  • Patent number: 6069114
    Abstract: Compounds of the formula (I) and their salts ##STR1## in which R.sup.1 to R.sup.6, Y.sup.1, to Y.sup.2, Y.sup.3, m and n are as defined in claim 1 are suitable as herbicides and plant growth regulators. They can be prepared analogously to known processes using intermediates of the formula (V) (cf. claim 6).
    Type: Grant
    Filed: February 25, 1997
    Date of Patent: May 30, 2000
    Assignee: Hoechst Schering AgrEvo GmbH
    Inventors: Klaus Lorenz, Klemens Minn, Lothar Willms, Klaus Bauer, Hermann Bieringer, Christopher Rosinger
  • Patent number: 6045586
    Abstract: The present invention relates to new compounds which are useful as ultraviolet absorbing agents (UVAs) and to a method of improving the sun protection factor (SPF) of textile fibre material treated with the new compounds.
    Type: Grant
    Filed: January 22, 1998
    Date of Patent: April 4, 2000
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Jean-Pierre Bacher, Werner Kaufmann, Dieter Reinehr
  • Patent number: 6004902
    Abstract: A triazine compound of the formula (I), ##STR1## wherein X.sup.1 is a linear or branched C.sub.1 -C.sub.4 alkyl group or a halogen atom; n is an integer of 0 or 1 to 4, provided that when n is 2 or more, a plurality of substituents X.sup.1 are the same or different; and R.sup.1 is a linear or branched C.sub.1 -C.sub.10 alkyl group which is optionally substituted with 1 to 4 C.sub.1 -C.sub.4 alkoxy groups and/or hydroxy groups, provided that when the linear or branched C.sub.1 -C.sub.10 alkyl group is substituted with 2 or more C.sub.1 -C.sub.4 alkoxy groups and/or hydroxy groups, a plurality of the C.sub.1 -C.sub.4 alkoxy groups and/or hydroxy groups are the same or different; a process for the production thereof, and a herbicide composition containing the compound. The triazine compounds exhibit excellent crops-weeds selectivity, even under poor conditions of excessive water content, etc., which are liable to cause phytotoxicity.
    Type: Grant
    Filed: October 27, 1997
    Date of Patent: December 21, 1999
    Assignee: Idemitsu Kosan Co., Ltd.
    Inventors: Mineyuki Kubota, Masatoshi Saitou, Kazuyoshi Koike, Shin-ichiro Ogawa
  • Patent number: 5969134
    Abstract: Carboxylic acid derivatives ##STR1## where R-R.sup.6, X, Y and Z have the meanings stated in the description, and the preparation thereof, are described. The novel compounds are suitable for controlling diseases.
    Type: Grant
    Filed: November 2, 1998
    Date of Patent: October 19, 1999
    Assignee: BASF Aktiengesellschaft
    Inventors: Hartmut Riechers, Dagmar Klinge, Wilhelm Amberg, Andreas Kling, Stefan Muller, Ernst Baumann, Joachim Rheinheimer, Uwe Josef Vogelbacher, Wolfgang Wernet, Liliane Unger, Manfred Raschack
  • Patent number: 5958933
    Abstract: A method for treating a mammal having a damaged central nervous system, as the result of trauma or disease, for reestablishing previously destroyed neurological functions in a traumatized or diseased mammal, or for controlling spasticity and for providing protection from such injury to the central nervous system. The method comprises administering to the mammal at least one neurologically active compound comprising two groups, one group providing alpha-adrenergic agonist activity, specifically a guanidino group, and the second group providing agonist activity selected from the group consisting of beta-adrenergic agonist activity, serotinergic agonist activity, and GABA-ergic agonist activity (for example a methylated xanthine group, having beta-adrenergic agonist activity) as the primary therapeutic agent. The neurologically active compound is administered in a dosage amount and at a dosage rate sufficient to at least partially restore the lost neurological function or to control spasticity.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: September 28, 1999
    Inventor: N. Eric Naftchi
  • Patent number: 5945396
    Abstract: The present invention provides a compound having the formula: ##STR1## in which each R.sub.d is the same or different and each is --NH--Z--N(R.sub.a)(R.sub.b) or --N--?Z--N(R.sub.a)(R.sub.b)!.sub.2 in which Z is C.sub.2 -C.sub.14 alkylene or optionally substituted arylene, R.sub.a and R.sub.b are the same or different and each is C.sub.1 -C.sub.12 alkyl, or R.sub.a and R.sub.b, together with the nitrogen atom to which they are each attached, form a morpholino, piperidino or piperazino ring; each R.sub.c is the same or different and is NH.sub.2, NH(C.sub.1 -C.sub.4 alkyl), N(C.sub.1 -C.sub.4 alkyl).sub.2, N(CH.sub.2 CH.sub.2 OH).sub.2, O--C.sub.1 -C.sub.4 alkyl, ##STR2## alkali metal atom, ammonium or a cation formed from an amine; or a quaternized form thereof.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: August 31, 1999
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Claude Eckhardt, Georges Metzger, Dieter Reinehr, Hanspeter Sauter, Mario Dubini
  • Patent number: 5936085
    Abstract: Disclosed and claimed is a process for the preparation of a carbamate (IV)Ar--O--CO--NR--B (IV)by reaction of a saltM.sup..sym. .crclbar.NR--B (II-S)with a diaryl carbonate(ArO).sub.2 CO (III).The carbamate can be reacted, without any necessity of intermediate isolation, with a sulfonamide A--SO.sub.2 NH.sub.2 (V) to give a sulfonylurea (I) or salts thereofA--SO.sub.2 --NH--CO--NR--B (I).And thus, disclosed and claimed too is a process for the preparation of sulfonylurea (I) by (i) contacting a salt (II-S) with a diaryl carbonate (III) to form a carbamate (IV), and (ii) contacting carbamate (IV) from step (i) with or without intermediate isolation, with a sulfonamide (V). These processes avoid the use of alkali metal hydrides as a base. And, these processes can additionally include the preparation of salt (II-S) from a compound H--NR--B (II) and base M.sup..sym. Base.sup..crclbar..
    Type: Grant
    Filed: July 11, 1996
    Date of Patent: August 10, 1999
    Assignee: Hoechst Schering AgrEvo GmbH
    Inventors: Gerhard Schnabel, Harald Knorr, Klemens Minn, Jan Vermehren
  • Patent number: 5925597
    Abstract: Compounds of the formula (I) and their salts as defined in claim 1, ##STR1## in which R.sup.1 is CO--Q--R.sup.8, where R.sup.8 =H or RR.sup.2 and R.sup.3 are H or (C.sub.1 -C.sub.4)alkyl,R.sup.4 is H, R, RO, OH, RCO, RSO.sub.2, PhSO.sub.2R.sup.5 is RSO.sub.2, PhSO.sub.2, PhCO, RNHSO.sub.2, R.sub.2 NSO.sub.2, RCO, CHO, COCOR', CW--T--R.sup.9, CW--NR.sup.10 R.sup.11, CW--N(R.sup.12).sub.2 orR.sup.4 and R.sup.5 together are the chain (CH.sub.2).sub.m B or --B.sup.1 --(CH.sub.2).sub.m1 B-- where B=SO.sub.2, CO; m=3, 4; m.sup.1 =2, 3;T and W=O, S; Q=O, S, NR.sup.13 where R.sup.13 =H, R;R.sup.6 =H, R, RO, RCO, ROCO, Hal, NO.sub.2, CN;R.sup.7 =H, CH.sub.3 ; R.sup.9 =R; R.sup.10, R.sup.11 =H, R; N(R.sup.12).sub.2 =heterocycleA=pyrimidinyl and triazinyl radical or an analog thereof,where R=(substituted) aliphatic hydrocarbon radical, are suitable as selective herbicides. They are prepared by analogous processes via sulfonamides, some of which are new, of the formula (II).
    Type: Grant
    Filed: March 31, 1997
    Date of Patent: July 20, 1999
    Assignee: Hoechst Schering AgrEvo GmbH
    Inventors: Klaus Lorenz, Lothar Willms, Klaus Bauer, Hermann Bieringer
  • Patent number: 5922648
    Abstract: Compounds of the formula (I) and salts thereof ##STR1## in which R.sup.1 to R.sup.9, X, Y n and m are as defined in the claim 1 are suitable as herbicides and plant growth regulators.
    Type: Grant
    Filed: June 17, 1996
    Date of Patent: July 13, 1999
    Assignee: Hoechst Schering AgrEvo GmbH
    Inventors: Klaus Lorenz, Klemens Minn, Lothar Willms, Klaus Bauer, Hermann Bieringer, Christopher Rosinger
  • Patent number: 5885935
    Abstract: Herbicidal sulfonamides of the formula: ##STR1## and salts thereof, where: A represents a substituted or unsubstituted benzene ring, or a 5- or 6-membered substituted or unsubstituted heteroaromatic ring; Q is --O--, --S-- or a group --CXX'--; X and X', which may be the same or different, are each hydrogen, halogen, cyano, an optionally-substituted alkyl group, or a group --OR.sup.a, --SR.sup.a, or --COR.sup.b ; or one of X and X' represents hydroxy and the other is as defined above; or X and X' together represent .dbd.O or .dbd.S; R.sup.a is an optionally-substituted alkyl, aryl or acyl group; R.sup.b is an optionally-substituted alkyl or aryl group, or a group --OR.sup.c or --NR.sup.c R.sup.d ; R.sup.c and R.sup.d, which may be the same or different, are each hydrogen, or an optionally-substituted alkyl or aryl group; Y is nitrogen or a group CR.sup.9 ; R.sup.1 is an optionally-substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocyclyl, benzoheterocyclyl or amino group; R.sup.
    Type: Grant
    Filed: June 21, 1996
    Date of Patent: March 23, 1999
    Assignee: Agrevo UK Limited
    Inventors: Peter Stuart Gates, Graham Peter Jones, David Edward Saunders
  • Patent number: 5886176
    Abstract: The invention relates to a novel process for preparing herbicidal sulphonylurea salts of the formula (I) ##STR1## in which M.sup.+ represents an alkali metal ion or an alkaline earth metal ion equivalent,Z represents N, CH or C-halogen,R.sup.1 represents in each case optionally substituted aryl, aralkyl or heteroaryl,(where R.sup.2, X and Y have the meanings given in the description).
    Type: Grant
    Filed: March 1, 1993
    Date of Patent: March 23, 1999
    Assignee: Bayer Aktiengesellschaft
    Inventor: Klaus-Helmut Muller
  • Patent number: 5792864
    Abstract: The present invention relates generally to carboxylated amino-1,3,5-triazines and the preparation thereof via carboxylation of amino-1,3,5-triazines with carbon dioxide and a base. These carboxylated amino-1,3,5-triazines find use, for example, as intermediates in the production of other useful amino-1,3,5-triazine derivatives, and particularly carbamate and isocyanate functional 1,3,5-triazines. The present invention also relates to the preparation of such carbamate and isocyanate functional 1,3,5-triazines.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: August 11, 1998
    Assignee: Cytec Technology Corp.
    Inventors: Lawrence Allen Flood, Ram Baboo Gupta
  • Patent number: 5792865
    Abstract: The present invention relates generally to carboxylated amino-1,3,5-triazines and the preparation thereof via carboxylation of amino-1,3,5-triazines with carbon dioxide and a base. These carboxylated amino-1,3,5-triazines find use, for example, as intermediates in the production of other useful amino-1,3,5-triazine derivatives, and particularly carbamate and isocyanate functional 1,3,5-triazines. The present invention also relates to the preparation of such carbamate and isocyanate functional 1,3,5-triazines.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: August 11, 1998
    Assignee: Cytec Technology Corp.
    Inventors: Lawrence Allen Flood, Ram Baboo Gupta
  • Patent number: 5741905
    Abstract: New compounds having the formula ##STR1## in which m is 1 or 2; when m is 1, A is a residue selected from those of the formulae ##STR2## and, when m is 2, A is a residue of the formula ##STR3## B is --O--, --NH-- or --SO.sub.2 --, and D is as defined herein, are useful as ultraviolet absorbing agents (UVAs) and a method of improving the sun protection factor of textile fibre material by treating the material with the new compounds.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: April 21, 1998
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Jean-Pierre Bacher, Werner Kaufmann, Dieter Reinehr
  • Patent number: 5736628
    Abstract: The present invention is directed to novel benzenesulfonylurea derivatives having herbicidal activity.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 7, 1998
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Dae-Whang Kim, Young Kwan Ko, Jin-Seog Kim, Dong Whan Ku
  • Patent number: 5686486
    Abstract: The present invention relates to compounds of formula I which are 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl?b!pyran-2-ones useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus. ##STR1## Wherein R.sub.10 and R.sub.
    Type: Grant
    Filed: August 4, 1995
    Date of Patent: November 11, 1997
    Assignee: Pharmacia & Upjohn Company
    Inventors: Paul Kosta Tomich, Michael John Bohanon, Steven Ronald Turner, Joseph Walter Strohbach, Suvit Thaisrivongs, Richard C. Thomas, Karen Rene Romines, Chih-Ping Yang, Paul Adrian Aristoff, Harvey Irving Skulnick, Paul D. Johnson, Ronald B. Gammill, Qingwei Zhang, Gordon L. Bundy, David John Anderson, Lee S. Banitt
  • Patent number: 5596039
    Abstract: Provided by the present invention are novel diguanamine derivatives, led by 2,5/2,6-bis(4,6-diamino-1,3,5-triazin-2-yl)-bicyclo[2.2.1]heptanes and 1,3/1,4-bis(4,6-diamino-1,3,5-triazin-2-yl)-cyclohexanes, and derivatives thereof, applications of these compounds in fields such as adhesives and paints, utilization of these compounds in flame-retarding, thermal stabilization and compatibilization methods of resins, thermosetting molding compositions and thermosetting expansion-molding compositions making use of these compounds, as well as polymeric microspheres also using these compounds. These compounds are expected to find wide spread industrial utility as various excellent properties can be obtained by using them.
    Type: Grant
    Filed: February 24, 1994
    Date of Patent: January 21, 1997
    Assignee: Mitsui Toatsu Chemicals, Incorporated
    Inventors: Tetsuya Oishi, Hiroshi Ozawa, Minato Karasawa, Masamitsu Inomata, Izumi Mega, Atsuyoshi Yamauchi
  • Patent number: 5571915
    Abstract: This invention provides a process for preparing amide derivatives of acids by the reaction of haloaminotriazines and acid halides.This invention also provides a process for preparing isocyanates and isocyanate adducts from amide derivatives derived from haloaminotriazines and acid halides such as oxalyl chloride, phosgene and phosgene analogs.Melamine derived acid amides are prepared by reaction of trichloro and hexachloromelamines with chloroformates and acid chlorides. The by-product chlorine may be recycled in this process.Amides, carbamates, sulfonamides, phosphoramides, and related amide derivatives may be prepared by the novel processes of the invention.
    Type: Grant
    Filed: March 3, 1995
    Date of Patent: November 5, 1996
    Assignee: Cytec Technology Corp.
    Inventor: Ram B. Gupta
  • Patent number: 5569761
    Abstract: Process for the preparation of sulfonylureasHerbicidal sulfonylureas of the formula I, ##STR1## in which X is --O--, --0--NR.sup.2 -- or --SO.sub.2 --NR.sup.2 --, Y is --N-- or CH,R.sup.1 is (substituted) alkyl, (substituted) alkenyl or (substituted) alkynyl, or else, where X.dbd.O, (substituted) phenyl,R.sup.2 is H, alkyl, alkenyl, alkynyl or cycloalkyl,R.sup.3, R.sup.4 are H, (substituted) alkyl or (substituted) alkoxy, halogen, alkylthio, alkylamino or dialkylamino andR.sup.5, R.sup.
    Type: Grant
    Filed: February 7, 1995
    Date of Patent: October 29, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Lothar Willms, Stephen Lacchein, Gunter Schlegel, Heinz Kehne
  • Patent number: 5550238
    Abstract: This invention relates to a process for preparing sulfonylureas comprising reacting a sulfonyl chloride with a cyanate salt and an amine base in the presence of an inert aprotic solvent to give an isocyanate complex which is then reacted with an amino heterocycle to form the sulfonylurea product and a process for converting the crystal form of the prepared sulfonylurea product to a more stable crystal product form.
    Type: Grant
    Filed: August 23, 1995
    Date of Patent: August 27, 1996
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: George C. Chiang, Richard F. Davis, Kwaku O. Temeng
  • Patent number: 5508402
    Abstract: A process for the preparation of substituted benzenes or benzenesulfonic acid and its derivatives comprising diazotisation of an aminobenzene or ortho-amino-benzenesulfonic acid derivative followed by homogeneous palladium-catalysed coupling with an olefine and heterogeneous palladium-catalysed hydrogenation of the olefinic substituent, wherein the homogeneous catalyst is reduced and precipitated as metal after the coupling in the reaction mixture and used as a heterogeneous palladium catalyst for the hydrogenation step. The process is particular suitable for the preparation N-benzenesulfon-N'-triazinyl-urea herbicides.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: April 16, 1996
    Assignee: Ciba-Geigy Corporation
    Inventors: Peter Baumeister, Gottfried Seifert, Heinz Steiner
  • Patent number: 5470921
    Abstract: A synthetic polyamide of formula I and its salts ##STR1## in which each R.sub.1 independently is selected from hydrogen, carboxyl, amino or a group of formula .alpha.-A.sub.1 -R.sub.10 (.alpha.)where A, is a bridging group and R.sub.10 is a sterically hindered amine group;each R.sub.2 independently is hydrogen or a group of formula .alpha.A is a bridging group of the formula ##STR2## is 0 or 1; R.sub.3 is hydrogen, C.sub.1-12 alkyl or is a significance of R.sub.10 ;R.sub.5 is hydrogen or C.sub.1-12 alkylR.sub.4 is a significance of R.sub.10 or a group of formula .alpha.; andp is an integer from 5 to 200;with the proviso that the compound of formula I contains 1-400 sterically hindered amine groups.
    Type: Grant
    Filed: May 20, 1994
    Date of Patent: November 28, 1995
    Assignee: Sandoz Ltd.
    Inventors: Bansi L. Kaul, Angelos-Elie Vougioukas, Jurgen Goldmann
  • Patent number: 5451666
    Abstract: A water-soluble dye having a reactive group of the Formula (1): ##STR1## wherein: R.sup.1 is H or optionally substituted alkyl;R.sup.2 is H or C.sub.1-4 -alkyl;L is a divalent organic spacer group; andV is vinyl or a group convertible to vinyl on treatment with aqueous alkali.The reactive dyes of the present invention are useful for coloring natural and artificial textile materials containing amino or hydroxyl groups.
    Type: Grant
    Filed: June 9, 1993
    Date of Patent: September 19, 1995
    Assignee: Zeneca Limited
    Inventor: Kenneth Anderton
  • Patent number: 5420257
    Abstract: A reactive dye comprising a 1,3,5-s-triazine group having a chromophoric group at two of the 2-, 4- and 6-positions and a substituent at the remaining 2-, 4- or 6-position selected from H, optionally substituted alkyl, optionally substituted phenyl, --CH(CO.sub.2 R.sup.1).sub.2, --NR.sup.1 SO.sub.2 R.sup.2, and --SO.sub.2 R.sup.2, wherein each R.sup.1 is H or alkyl and R.sup.2 is alkyl. The reactive dyes may be used for the coloration of textile materials.
    Type: Grant
    Filed: September 17, 1993
    Date of Patent: May 30, 1995
    Assignee: Zeneca Limited
    Inventors: Kenneth Anderton, Andrew P. Shawcross
  • Patent number: 5418212
    Abstract: The present invention provides a novel alkanoic acid amide derivative of the formula, ##STR1## (wherein R.sup.1 is a hydrogen atom, an alkyl group or an alkoxyalkoxy group, R.sup.2 is a group of --SO.sub.2 R or a hydroxyl group, R.sup.5 is an alkyl group, R.sup.3 is an alkyl group, a cycloalkyl group, a cycloalkenyl group or a phenyl group, R.sup.4 is a hydrogen atom or an alkyl group, X and Y may be the same or different and are an alkoxy group, an alkylamino group or a dialkylamino group, and Z is a methine group or a nitrogen atom) and its salt, a process for preparing the same and a herbicidal composition containing the same as an effective ingredient.This compound kills annual and perennial weeds grown in paddy fields and upland fields at a small dose, and is safe to a useful crop plant.
    Type: Grant
    Filed: April 27, 1993
    Date of Patent: May 23, 1995
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Takumi Yoshimura, Keiji Toriyabe, Katsumi Masuda, Ryo Hanai
  • Patent number: 5410051
    Abstract: Disclosed are novel nitrogen containing heterocyclic compounds and novel vinyl terminated polyurethane/polyamide polymers together with the use of both of these compounds in a novel adhesive and coating composition. The nitrogen containing heterocyclic compounds of the invention contain two vinyl-terminated substituents and at least one carbamylmethyl substituent and have a nucleus selected from melamine, oligomers of melamine, benzoguanamine, and oligomers of benzoguanamine, glycoluril and oligomers of glycoluril, cyclohexylguanamine, oligomers of cyclohexylguanamine, acetoguanamine, and oligomers of acetoguanamine. The vinyl terminated polyurethane compounds of the invention have a molecular weight of from about 3000 to about 80000, and contain at least two vinyl end groups.
    Type: Grant
    Filed: June 17, 1993
    Date of Patent: April 25, 1995
    Assignee: Cytec Technology Corp.
    Inventors: Peter S. Forgione, William A. Henderson, Balwant Singh, Yuhshi Luh
  • Patent number: 5405959
    Abstract: This invention provides a process for preparing amide derivatives of acids by the reaction of haloaminotriazines and acid halides.This invention also provides a process for preparing isocyanates and isocyanate adducts from amide derivatives derived from haloaminotriazines and acid halides such as oxalyl chloride, phosgene and phosgene analogs.Melamine derived acid amides are prepared by reaction of trichloro and hexachloromelamines with chloroformates and acid chlorides. The by-product chlorine may be recycled in this process.Amides, carbamates, sulfonamides, phosphoramides, and related amide derivatives may be prepared by the novel processes of the invention.
    Type: Grant
    Filed: November 10, 1993
    Date of Patent: April 11, 1995
    Assignee: Cytec Technology Corp.
    Inventor: Ram B. Gupta
  • Patent number: 5380843
    Abstract: Phenyl (1,3,5-triazin-2-yl)carbamates of the formula (I): ##STR1## wherein R.sup.1 is H, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy, R.sup.2 and R.sup.3 are independently H, halogen atom, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkylthio, C.sub.2 -C.sub.4 alkoxyalkyl or NR.sup.7 R.sup.8 (R.sup.7, R.sup.8 : H or C.sub.1 -C.sub.4 alkyl, independently), and R.sup.4, R.sup.5 and R.sup.6 are independently H, halogen atom, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy, are prepared by reacting a 2-amino-1,3,5-triazine of the formula (II): ##STR2## with a diphenyl carbonate of the formula (III): ##STR3## in the presence of an alkali metal hydride in an acrotic polar solvent. An parotic polar solvent mixture of the phenyl (1,3,5-triazin-2-yl)carbamate of the formula (I) and an alkali metal phenoxide is also disclosed.
    Type: Grant
    Filed: May 19, 1993
    Date of Patent: January 10, 1995
    Assignee: Kureha Kagaku Kogyo K.K.
    Inventors: Yoichi Kanda, Hideo Arabori
  • Patent number: 5374725
    Abstract: A compound of formula I or salt thereof can be prepared in a process which comprises reacting a compound of formula II with a compound of formula III: ##STR1## wherein the formulae I-III the radical X is O, ONR.sup.2 or SO.sub.2 NR.sup.2 ; Y is N or CH;R.sup.1 is (subst.) alkyl, (subst.) alkenyl, (subst.) alkynyl, or in case X.dbd.O, also (subst.) phenyl;R.sup.2 is H, alkyl, alkenyl, alkynyl or cycloalkyl,R.sup.3 -R.sup.6 are defined in claim 1;Z is S or NR.sup.8 ; R.sup.7, R.sup.8 are H, alkyl, (subst.) phenyl or (subst.) benzyl, or, in case Z.dbd.NR.sup.8, R.sup.7 and NR.sup.8 are also a 5- to 7-membered heterocycle.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: December 20, 1994
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gunter Schlegel, Hilmar Mildenberger
  • Patent number: 5364937
    Abstract: Compounds of the formula I or salts thereof, ##STR1## in which X is oxygen, --O--NR.sup.2 -- or --SO.sub.2 --NR.sup.2 --, and Y is N or CH,R.sup.1 is (C.sub.1 -C.sub.6)alkyl, (C.sub.2 -C.sub.6)alkenyl or (C.sub.2 -C.sub.6)alkynyl, which are in each case optionally substituted, or, in the case where X=oxygen, also (subst.) phenyl,R.sup.2 is H, (C.sub.1 -C.sub.6)alkyl, (C.sub.2 -C.sub.6)alkenyl or -alkynyl or (C.sub.3 -C.sub.6) cycloalkyl,R.sup.3 and R.sup.4 are H, (subst.) (C.sub.1 -C.sub.4)alkyl or (subst.) (C.sub.1 -C.sub.4)alkoxy or halogen, (C.sub.1 -C.sub.4)alkylthio, (C.sub.1 -C.sub.4)alkylamino or di[(C.sub.1 -C.sub.4)alkyl]-amino,R.sup.5 is H or (C.sub.1 -C.sub.4)alkyl and R.sup.6 is hydrogen,may be prepared by reacting compounds of the formula II,R.sup.1 --X--R.sup.7 (II)with compounds of the formulae III, IV and VR.sup.8 --OCN (III)SO.sub.2 Cl.sub.2 (IV) ##STR2## where R.sup.7 and R.sup.8 are H, a quarternary ammonium ion or one equivalent of a metal cation.
    Type: Grant
    Filed: March 4, 1993
    Date of Patent: November 15, 1994
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Gunter Schlegel
  • Patent number: 5334709
    Abstract: Fiber-reactive dyestuffs, such as, for example, azo dyestuffs and heavy metal complex derivatives thereof, anthraquinone dyestuffs, phthalocyanine dyestuffs and formazan dyestuffs, which contain a fiber-reactive group of the vinylsulfone series and furthermore a group of the general formula ##STR1## in which R.sup.x is hydrogen or lower alkyl, which can be substituted by substituents customary in dyestuffs, and Q.sup.1 and Q.sup.2 both independently of one another are each lower alkyl, which is substituted by 1 or 2 lower alkanoyl groups or 1 or 2 lower alkoxycarbonyl groups or by one such alkoxycarbonyl and alkanoyl group, or an amino group, which is substituted by optionally substituted aryl and/or alkyl radicals, or an optionally substituted alkoxy, aryloxy, alkylthio or arylthio radical or a cyanamido radical, are described.
    Type: Grant
    Filed: December 18, 1992
    Date of Patent: August 2, 1994
    Assignee: Hoechst AG
    Inventors: Jorg Dannheim, Werner H. Russ
  • Patent number: 5326869
    Abstract: A process for the preparation of a 5,7-diaryloxy-2-(2-heteroaryl)-triazolo[1,5-a][1,3,5]triazine, which comprises reacting a N-2-(4,6-diaryloxy)-[1,3,5]triazinyl-N'-(2-heteroarylcarbonyl)hydrazine with a polyphosphoric acid silyl ester. The invention also provides a multistep process for preparing certain triazolotriazines having activity asadenosine antagonists.
    Type: Grant
    Filed: November 20, 1992
    Date of Patent: July 5, 1994
    Assignee: Imperial Chemical Industries, PLC
    Inventor: Jonathan Hutton
  • Patent number: 5300503
    Abstract: Insects, and particularly the larvae of Lepidoptera and Coleoptera, are controlled by application of 4,6-diamino-1,2-dihydro-dihydro-1,3,5-trazine derivatives, and agriculturally acceptable salts thereof, having the following structure; ##STR1## when they are admixed with a compatible agricultural vehicle; additionally, certain related novel heterocyclyl, phenyl, and naphthyl triazines and their substituted counterparts are also taught.
    Type: Grant
    Filed: November 1, 1991
    Date of Patent: April 5, 1994
    Assignee: FMC Corporation
    Inventors: Clinton J. Peake, Thomas G. Cullen, Albert C. Lew
  • Patent number: 5290754
    Abstract: The present invention relates to a novel triazine derivative represented by the general formula ##STR1## in the formula, A denotes ##STR2## (in which Y.sup.1 denotes a hydrogen atom or a methyl group and Z denotes an oxygen atom or a sulfur atom), ##STR3## (in which Y.sup.2 and Y.sup.3, which can be of the same kind or different kinds, each denote a methyl group or a methoxy group) or ##STR4## (in which Y.sup.4 denotes a methyl group, trifluoromethyl group, methoxy group or fluorine atom and n denotes an integer of 0 ro 2), X.sup.1 denotes a halogen atom and R.sup.1 denotes hydrogen, a methyl group or an ethyl group as well as a herbicide containing the triazine derivative represented by the general formula (I) as an effective ingredient.
    Type: Grant
    Filed: October 5, 1990
    Date of Patent: March 1, 1994
    Assignee: Idemitsu Kosan Company Limited
    Inventors: Masahiro Nishii, Izumi Kobayashi, Masatoshi Uemura, Tetsuo Takematsu
  • Patent number: 5288865
    Abstract: This invention provides a process for preparing amide derivatives of acids by the reaction of haloaminotriazines and acid halides.This invention also provides a process for preparing isocyanates and isocyanate adducts from amide derivatives derived from haloaminotriazines and acid halides such as oxalyl chloride, phosgene and phosgene analogs.Melamine derived acid amides are prepared by reaction of trichloro and hexachloromelamines with chloroformates and acid chlorides. The by-product chlorine may be recycled in this process.Amides, carbamates, sulfonamides, phosphoramides, and related amide derivatives may be prepared by the novel processes of the invention.
    Type: Grant
    Filed: October 30, 1992
    Date of Patent: February 22, 1994
    Assignee: American Cyanamid Company
    Inventor: Ram B. Gupta
  • Patent number: 5284946
    Abstract: There are described new triazinyl-substituted acrylic esters of the formula (I) ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, X and Y have the meaning given in the description, and a process for their preparation.The new acrylic esters of the formula (I) are used for the preparation of pesticides.
    Type: Grant
    Filed: March 11, 1993
    Date of Patent: February 8, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Peter C. Knuppel, Dieter Berg, Stefan Dutzmann, Heinz-Wilhelm Dehne, Gerd Hanssler
  • Patent number: 5280110
    Abstract: Water-soluble dyes, such as, for example, azo dyes, heavy metal complex azo dyes, anthraquinone, phthalocyanine and formazan dyes containing the group of the formula ##STR1## are described, in which R.sup.x is hydrogen or substituted or unsubstituted lower alkyl, U is hydrogen, cyano, lower alkanoyl, lower alkoxycarbonyl, nitro, lower alkylsulfonyl or substituted or unsubstituted arylsulfonyl, V is cyano, lower alkoxycarbonyl, substituted or unsubstituted aryloxycarbonyl, carboxy, lower alkylaminocarbonyl, substituted or unsubstituted arylaminocarbonyl, lower alkylcarbonyl, substituted or unsubstituted arylcarbonyl or arylsulfonyl, aminocarbonyl, dialkylaminocarbonyl, trifluoromethyl, nitro or lower alkylsulfonyl and Q is an amino group which is mono- or disubstituted by the radical --W--(SO.sub.2 --Y).sub.
    Type: Grant
    Filed: December 18, 1992
    Date of Patent: January 18, 1994
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Jorg Dannheim, Andreas v.d. Eltz
  • Patent number: 5258513
    Abstract: New substituted cyclopropylamino-1,3,5-triazines having the formula ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.3 -alkyl, C.sub.3 -C.sub.5 -cycloalkyl or C.sub.1 -C.sub.3 -alkyl-C.sub.3 -C.sub.5 -cycloalkylR.sub.2 is bis(2-hydroxyethyl)amino, 3-hydroxy-1-azetidinyl, 3-methoxy-1-azetidinyl, 3-oxo-1-azetidinyl, morpholino, 4-hydroxypiperidino, thiomorpholino, thiomorpholino S-oxide, thiomorpholino S,S-dioxide, 3-thiazolidinyl, 3-thiazolidinyl S-oxide, 3-thiazolidinyl S,S-dioxide or 8-oxa-3-azabicyclo[3,2,1]oct-3-yl. Processes for the preparation thereof and pharmaceutical composition containing them are also given. The compounds are useful for the treatment of disorders associated with Alzheimer's disease, senile dementia, Alzheimer's type and with any evolutive cognitive pathology, and also for the treatment of depression, anxiety, mood disturbances, inflammatory phenomena and asthma.
    Type: Grant
    Filed: July 20, 1992
    Date of Patent: November 2, 1993
    Assignee: UCB S.A.
    Inventors: Berend Jan Van Keulen, Solo Goldstein, Eric Cossement, Jean Gobert, Ernst Wulfert
  • Patent number: 5258514
    Abstract: Novel s-triazine compounds containing at least one N,N-bis(alkoxy or hydroxyalkoxy-carbonyl-amino C.sub.2 -C.sub.10 alkyl) amino substituent function in self-condensation and as cross-linkers for compounds containing active hydrogen groups. The compositions cure to coatings with excellent properties, especially corrosion resistance, humidity resistance, abrasion resistance and flexibility. The coatings have excellent exterior durability.
    Type: Grant
    Filed: May 14, 1992
    Date of Patent: November 2, 1993
    Assignee: American Cyanamid Company
    Inventor: Girish G. Parekh
  • Patent number: 5250686
    Abstract: A process for producing a triazine derivative of the formula (III), ##STR1## wherein R.sup.1 is a C.sub.1 -C.sub.4 alkyl group, n is an integer of O to 2, R.sup.2 is hydrogen or a C.sub.1 -C.sub.2 alkyl group, and X is a halogen atom,which comprises reacting a biguanide derivative of the formula, ##STR2## wherein R.sup.1 and n are as defined in the formula (III), and X' is a halogen atom,with a halocarboxylic acid ester of the formula, ##STR3## wherein R.sup.2 and X are as defined in the formula (III), and R.sup.3 is a C.sub.1 -C.sub.4 alkyl group,in the presence of a base, wherein a dehydrating agent is present in the reaction system, and processes for producing 2-fluoroisobutyric acid ester as an intermediate compound for the production of the triazine derivative.
    Type: Grant
    Filed: April 14, 1992
    Date of Patent: October 5, 1993
    Assignee: Idemitsu Kosan Company Limited
    Inventors: Ryoichi Adachi, Kazufumi Nakamura, Masahiro Nishii, Masahiro Yoshida, Izumi Terada, Hidetoshi Koga