Heavy Metal Or Aluminum Containing Patents (Class 544/64)
  • Patent number: 5068371
    Abstract: Titanocenes of the formula I ##STR1## in which R.sup.1 are cyclopentadienyl.sup..crclbar. groups and R.sup.2 and R.sup.3 are aromatic radicals which are substituted in both ortho-positions by fluorine and, in addition, are substituted by a pyrrylalkyl group, amidoalkyl group or imidoalkyl group, are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated compounds.
    Type: Grant
    Filed: May 23, 1990
    Date of Patent: November 26, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Eginhard Steiner, Harry Beyeler, Rinaldo Husler
  • Patent number: 5030729
    Abstract: Compounds of formula (I) ##STR1## in which R.sub.1 is hydrogen, O.degree., CN, NO, cyanomethyl, C.sub.1 -C.sub.12 -alkyl, C.sub.3 -C.sub.12 -alkenyl or C.sub.3 -C.sub.12 -alkynyl subject to the proviso that the carbon atom attached to the nitrogen atom is a primary carbon atom, C.sub.7 -C.sub.12 -aralkyl, C.sub.1 -C.sub.12 -acyl, 2,3-epoxypropyl, OH-monosubstituted C.sub.2 -C.sub.6 -alkyl or 2,3-dihydroxypropyl, R.sub.2 is hydrogen, C.sub.1 -C.sub.18 -alkyl, C.sub.5 -C.sub.18 -cycloalkyl, C.sub.6 -C.sub.18 -aryl or C.sub.7 -C.sub.18 -aryalkyl, R.sub.3 is C.sub.6 -C.sub.18 -aryl or a group of the formula (II) ##STR2## in which R.sub.1 is as defined above, n is an integer from 1 to 4 and R.sub.4 is an organic or inorganic radical of a valency equal to n are useful for stabilizing organic material against oxidative, thermal and/or light induced degradation.
    Type: Grant
    Filed: March 1, 1990
    Date of Patent: July 9, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Giuseppe Cantatore, Valerio Borzatta
  • Patent number: 4975433
    Abstract: A compound of the formula: ##STR1## wherein: R and R.sub.1 may be the same or different and are selected from the group consisting of H; cycloalkyl groups having up to 10 carbon atoms; or straight or branched chain alkyl, alkenyl or alkynyl of 1 to 10 carbon atoms;R.sub.2 and R.sub.3 together with the nitrogen atom to which they are bonded form a pyrrolidine, piperidine, N-methyl piperazine, piperazine or morpholine ring;or a non-toxic pharmaceutically acceptable salt, adduct, oxide or other derivative thereof; and pharmaceutical compositions adapted for topical administration to a human or non-human animal and methods of topically administering the compositions to humans and non-human animals.
    Type: Grant
    Filed: January 31, 1989
    Date of Patent: December 4, 1990
    Assignee: University of Florida
    Inventor: Kenneth B. Sloan
  • Patent number: 4963470
    Abstract: Titanocenes with silylated .pi.-cyclopentadienyl ligands in which one or two carbo- or heterocyclic aromatic rings are bonded to the titanium, the aromatic rings being substituted by fluorine, --CF.sub.3, --C.sub.2 F.sub.5, --CF.sub.2 CL or --CF.sub.2 CH.sub.3 in at least one of the two ortho-positions relative to the metal-carbon bonds, are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated substrates. They are distinguished by a high sensitivity, stability to air and the action of heat, and a high activity in the region of UV light to visible light. They are furthermore readily soluble in the photopolymerizable compositions.
    Type: Grant
    Filed: January 19, 1990
    Date of Patent: October 16, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Bernd Klingert, Franciszek Sitek, Manfred Rembold
  • Patent number: 4952289
    Abstract: Methods and apparatus for electrochemical extraction of a ligand such as molecular oxygen from a first fluid environment and for release of a ligand such as molecular oxygen, as well as ligand carrier compounds therefor comprising macrocyclic amines having the general formulas: ##STR1## where: A, B, C, D, E, and F are each nitrogen, oxygen, sulfur, or phosphorous;m, n, o, p, q, and r are each typically 2, 3, 4, 5, or 6;the R substituents are each generally H or short chain (linear or branched) alkyl, although R.sub.2 may represent ketyl (.dbd.o); andM is a suitable transition metal ion.
    Type: Grant
    Filed: May 9, 1988
    Date of Patent: August 28, 1990
    Assignee: Aquanautics Corporation
    Inventors: Joseph P. Ciccone, Emory S. DeCastro, John B. Kerr
  • Patent number: 4940696
    Abstract: A benzonaphthalene compound has the formula ##STR1## wherein R.sub.1 represents ##STR2## or (ii) --CH.sub.2 OH; R.sub.6 represents ##STR3## or OR.sub.7 wherein R.sub.7 represents hydrogen, alkyl having 1-20 carbon atoms, monohydroxyalkyl or polyhydroxyalkyl, r' or r" represent hydrogen, lower alkyl, mono or polyhydroxyalkyl, aryl or a residue of an amino acid or a sugar, or together form a heterocycle; R.sub.2 represents hydrogen, alkyl having 1-15 carbon atoms, alkoxy having 1-4 carbon atoms or a cycloaliphatic radical; R.sub.3 represents hydrogen, hydroxy, alkyl having 1-4 carbon atoms, alkoxy having 1-10 carbon atoms, a cycloaliphatic radical, a thiocycloaliphatic radical or --O--Si(CH.sub.3).sub.2 --R.sub.8 wherein R.sub.8 represents lower alkyl; and R.sub.4 and R.sub.5 represent hydrogen, lower alkyl, hydroxy or lower acyloxy.This compound is useful in the topical and systemic treatment of dermatologic diseases and in the treatment of the degeneration of conjunctive tissues.
    Type: Grant
    Filed: November 16, 1987
    Date of Patent: July 10, 1990
    Assignee: Centre International de Recherches Dermatologioues (CIRD)
    Inventors: Braham Shroot, Jacques Eustache, Jean-Michel Bernardon
  • Patent number: 4937338
    Abstract: Pigment of the general formula:f.Het (I)where F is the cation of a cationic dye which has an absorption maximum at >700 nm and may or may not contain anionic groups and Het is an anion of a heteropolyacid based on tungsten, molybdenum, vanadium or a mixture of these with phosphorus, silicon, cobalt, aluminum, manganese, chromium, nickel or a mixture of these or a copper (I)-hexacyanoferrate(II) anion, are superior to the known IR dyes in terms of thermal stability and photostability, and give optical recording media having superior properties, such as a high signal/noise ratio.
    Type: Grant
    Filed: April 20, 1989
    Date of Patent: June 26, 1990
    Assignee: BASF Aktiengesellschaft
    Inventors: Helmut Flohr, Joachim Jesse, Bernhard Albert, Peter Neumann
  • Patent number: 4921963
    Abstract: Complexes of platinum II containing a single radiosensitizer ligand and an amino or ammine substituent shows superior binding to DNA and are useful in chemotherapy and sensitization of hypoxic tumors to radiation. The chemotherapeutic value of these compounds is enhanced by administration of vasoactive agents.
    Type: Grant
    Filed: April 13, 1987
    Date of Patent: May 1, 1990
    Assignee: British Columbia Cancer Foundation
    Inventors: Kirsten A. Skov, Nicholas P. Farrell, David J. Chaplin
  • Patent number: 4910121
    Abstract: Titanocenes containing .pi.-cyclopentadienyl ligands, in which one or two carbocyclic or heterocyclic aromatic rings are attached to the metal atom, said aromatic rings being substituted by fluorine in at least one of the two ortho-positions relative to the metal-carbon bonds, are suitable photoinitiators for the photopolymerization of ethylenically unsaturated substrates. They are distinguished by high sensitivity, stability to air and heat, and are very effective in the range from UV light to visible light.
    Type: Grant
    Filed: July 28, 1987
    Date of Patent: March 20, 1990
    Assignee: Ciba-Geigy Corporation
    Inventors: Martin Riediker, Martin Roth, Niklaus Buhler, Joseph Berger
  • Patent number: 4874867
    Abstract: Tetrazole intermediates useful to prepare antihypertensive compounds described in coassigned application U.S. Ser. No. 884,920, filed July 11, 1986, are described, these tetrazoles have the formula: ##STR1## wherein X.sup.1 and X.sup.2 are as described in the specification.
    Type: Grant
    Filed: November 23, 1988
    Date of Patent: October 17, 1989
    Assignee: E. I. Du Pont De Nemours and Company
    Inventors: Paul E. Aldrich, John Jonas V. Duncia, Michael E. Pierce
  • Patent number: 4855468
    Abstract: Titanocenes with .pi.-cyclopentadienyl ligands, in which one or two carbocyclic or heterocyclic aromatic rings are bonded to the metal, the aromatic rings being substituted in at least one of the two ortho-positions relative to the metal-carbon bonds by CF.sub.2 Z (Z=F or substituted or unsubstituted alkyl), are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated compounds. They are distinguished by a high radiation sensitivity, stability to air and thermal effects, and high effectiveness in the range from UV light to visible light.
    Type: Grant
    Filed: September 11, 1987
    Date of Patent: August 8, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Martin Riediker, Kurt Meier, Hans Zweifel
  • Patent number: 4851549
    Abstract: Pigments of the general formulaF.multidot.Het (I)where F is the cation of a cationic dye which has an absorption maximum at >700 nm and may or may not contain anionic groups and Het is an anion of a heteropolyacid based on tungsten, molybdenum, vanadium or a mixture of these with phosphorus, silicon, cobalt, aluminum, manganese, chromium, nickel or a mixture of these or a copper(I)-hexacyanoferrate(II) anion, are superior to the known IR dyes in terms of thermal stability and photostability, and give optical recording media having superior properties, such as a high signal/noise ratio.
    Type: Grant
    Filed: August 23, 1988
    Date of Patent: July 25, 1989
    Assignee: BASF Aktiengesellschaft
    Inventors: Helmut Flohr, Joachim Jesse, Bernhard Albert, Peter Neumann
  • Patent number: 4843068
    Abstract: A pyrazole oxime derivative represented by the general formula (I) which is useful as an insecticide and fungicide, ##STR1## wherein the structural elements are defined in the specification, and the method of controlling said pests. The compounds represented by the general formula (I) can be synthesized by the methods disclosed in the specification.
    Type: Grant
    Filed: December 29, 1986
    Date of Patent: June 27, 1989
    Assignee: Nihon Nohyaku Co., Ltd.
    Inventors: Hiroshi Hamaguchi, Hideo Takaishi, Tetsuji Ohshima, Takamichi Konno, Yukio Miyagi, Shiraiwa Yutaka, Takayuki Akita
  • Patent number: 4820843
    Abstract: Tetrazole intermediates useful to prepare antihypertensive compounds described in coassigned application U.S. Ser. No. 884,920, filed July 11, 1986, are described, these tetrazoles have the formula: ##STR1## wherein X.sup.1 and X.sup.2 are as described in the specification.
    Type: Grant
    Filed: May 22, 1987
    Date of Patent: April 11, 1989
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Paul E. Aldrich, John Jonas V. Duncia, Michael E. Pierce
  • Patent number: 4810782
    Abstract: Novel chelates of 2,6-diureadopyridines and certain metal ions are provided which exhibit exceptional fluorescent characteristics when such chelates are exposed to incident or X-ray irradiation.
    Type: Grant
    Filed: November 2, 1987
    Date of Patent: March 7, 1989
    Inventor: Spyros Theodoropulos
  • Patent number: 4791204
    Abstract: Compositions comprising(a) a pyrrolopyrrole of formula I ##STR1## wherein A and B are identical or different alkyl, aralkyl, aryl or heterocyclic aromatic radicals, R.sub.1 and R.sub.2 are hydrogen atoms, unsubstituted or substituted alkyl radicals, and also alkenyl, alkynyl, aralkyl, cycloalkyl, carbamoyl, alkylcarbamoyl, arylcarbamoyl, alkoxycarbonyl, aryl, alkanoyl or aroyl groups, and X is an --O-- or --S-- atom, and(b) a pyrrolopyrrole of the above formula I that contains at least one group of formula --SO.sub.3 L, --CO.sub.2 L, --PO.sub.3 (L).sub.2, --N(R.sub.4)(R.sub.5 ), ##STR2## oder --NHCOR wherein L is --H, a group of formula M.sub.n.sup.+n or N.sup.+ H(R.sub.3)(R.sub.4)(R.sub.5), M is a monovalent, divalent or trivalent metal cation, n is 1, 2 or 3, R.sub.3 R.sub.4 and R.sub.5 are each independently --H or alkyl, aralkyl, C.sub.5 -C.sub.6 cycloalkyl or aryl radicals, or R.sub.4 and R.sub.
    Type: Grant
    Filed: November 19, 1986
    Date of Patent: December 13, 1988
    Assignee: Ciba-Geigy Corporation
    Inventors: Max Jost, Abul Iqbal, Alain C. Rochat
  • Patent number: 4786721
    Abstract: The reactive dyes are useful, in particular, for dyeing or printing cellulose-containing fiber materials by the cold pad-batch method and produce, with a high dyeing yield, dyeings and prints having good fastness properties.
    Type: Grant
    Filed: August 13, 1986
    Date of Patent: November 22, 1988
    Assignee: Ciba-Geigy Corporation
    Inventors: Athanassios Tzikas, Peter Aeschlimann, Paul Herzig
  • Patent number: 4743294
    Abstract: A selective herbicide of the formula ##STR1## in which m is 0, 1 or 2,R.sup.5 is an organic radical,R.sup.3 is hydrogen or an organic radical,R.sup.9 is hydrogen or an optionally substituted alkyl radical,R.sup.10 is an organic radical or forms a ring with R.sup.9,R.sup.40 and R.sup.41 are alkyl or alkoxy, andM is hydrogen or a metal or ammonium radical, or an acid adduct thereof.
    Type: Grant
    Filed: April 22, 1987
    Date of Patent: May 10, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Joachim Diehr, Christa Fest, Rolf Kirsten, Joachim Kluth, Klaus-Helmut Muller, Theodor Pfister, Uwe Priesnitz, Hans-Jochem Riebel, Wolfgang Roy, Hans-Joachim Santel, Robert R. Schmidt, Koichi Moriya, Ludwig Eue, Klaus Lurssen
  • Patent number: 4734406
    Abstract: Compounds of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and Y have the indicated meanings, their physiologically tolerated acid addition salts, and a process for the preparation of these compounds, are described. The compounds inhibit thromboxane synthetase and can thus be used as medicaments.
    Type: Grant
    Filed: March 11, 1986
    Date of Patent: March 29, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Hermann Lau, Wilhelm Bartmann, Gerhard Beck, Gunther Wess
  • Patent number: 4732893
    Abstract: Platinum complex having formula (I)cis-[L-(Pt.sup.II XX').sub.m ].(Solv).sub.n (I)whereinm is 1 or 2;X and X', which are the same or different, are Cl, OH, CH.sub.3 SOCH.sub.3.Cl or CH.sub.3 SOCH.sub.3.H.sub.2 O;L is a bidentate ligand of formula II ##STR1## Solv. represents the crystallization solvents and m is zero, 0.5 or an integer from 1 to 6,are described.The compounds I are useful in therapy as antitumoral agents.
    Type: Grant
    Filed: August 2, 1985
    Date of Patent: March 22, 1988
    Assignee: Boehringer Biochemia Robin S.p.A.
    Inventors: Alessandro Pasini, Franco Zunino, Odoardo Tofanetti, Carmelo A. Gandolfi, Sergio Tongnella
  • Patent number: 4725305
    Abstract: Herbicidally active novel N,N'-bis-sulphonyl guanidines of the formula ##STR1## in which M is hydrogen, a metal or an ammonium radical, andR.sup.4, R.sup.5, R.sup.40 and R.sup.41 are various organic radicals.
    Type: Grant
    Filed: November 14, 1986
    Date of Patent: February 16, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Koichi Moriya, Theodor Pfister, Hans-Jochem Riebel, Ludwig Eue, Robert R. Schmidt, Klaus Lurssen, Hans-Joachim Diehr, Christa Fest, Rolf Kirsten, Joachim Kluth, Klaus-Helmut Muller, Uwe Priesnitz, Wolfgang Roy, Hans-Joachim Santel
  • Patent number: 4691037
    Abstract: A ruthenium-phosphine complex represented by the formula (I)Ru.sub.x H.sub.y Cl.sub.z (R--BINAP).sub.2 (S).sub.p (I)wherein R--BINAP represents tertiary phosphine represented by the formula (II) ##STR1## R which is the same represents hydrogen, methyl or t-butyl, S represents tertiary amine, y represents 0 or 1, and when y is 0, x represents 2, z represents 4 and p represents 1, and when y is 1, x represents 1, z represents 1 and p represents 0.
    Type: Grant
    Filed: January 6, 1986
    Date of Patent: September 1, 1987
    Assignee: Takasago Perfumery Co., Ltd.
    Inventors: Sadao Yoshikawa, Masahiko Saburi, Takao Ikariya, Youichi Ishii, Susumu Akutagawa
  • Patent number: 4657903
    Abstract: This invention relates to novel transition metal complexes of 2-acetyl- and -propionylpyridine thiosemicarbazones, their selenium analogs. These compounds are useful as antimalarial and antileukemic agents. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones and their selenium analogs.
    Type: Grant
    Filed: March 31, 1982
    Date of Patent: April 14, 1987
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: John P. Scovill, Daniel L. Klayman, Charles F. Franchino
  • Patent number: 4637988
    Abstract: There are described stable fluorescent labels comprising a complex of lanthanide metal and a chelating agent comprising a nucleus which is a triplet sensitizer having a triplet energy greater than that of said lanthanide metal and at least two heteroatom-containing groups which form coordinate complexes with lanthanide metals and a third heteroatom-containing group or heteratom in or appended to the triplet sensitizer. Labeled physiologically active materials useful in specific binding assays such as labeled antigens, heptens, antibodies, hormones and the like comprising the stable fluorescent labels having physiologically active materials adsorbed or bonded thereto are also described.
    Type: Grant
    Filed: February 3, 1986
    Date of Patent: January 20, 1987
    Assignee: Eastman Kodak Company
    Inventors: Jerald C. Hinshaw, John L. Toner, George A. Reynolds
  • Patent number: 4590287
    Abstract: Titanocenes containing .pi.-cyclopentadienyl ligands, in which one or two carbocyclic or heterocyclic aromatic rings are attached to the metal atom, said aromatic rings being substituted by fluorine in at least one of the two ortho-positions relative to the metal-carbon bonds, are suitable photoinitiators for the photopolymerization of ethylenically unsaturated substrates. They are distinguished by high sensitivity, stability to air and heat, and are very effective in the range from UV light to visible light.
    Type: Grant
    Filed: February 2, 1984
    Date of Patent: May 20, 1986
    Assignee: Ciba-Geigy Corporation
    Inventors: Martin Riediker, Martin Roth, Niklaus Buhler, Joseph Berger
  • Patent number: 4588811
    Abstract: There are described novel cationic quinophthalone compounds of the formula I ##STR1## wherein the symbols have the meanings defined in claim 1, and also processes for producing them. These novel quinophthalone compounds can be used in particular as dyes for dyeing and printing paper, greenish-yellow dyeings having good fastness to water and to light being obtained.
    Type: Grant
    Filed: November 19, 1984
    Date of Patent: May 13, 1986
    Assignee: Ciba-Geigy Corporation
    Inventor: Jean-Marie Adam
  • Patent number: 4569993
    Abstract: An antibacterial 7beta-substituted malonamido-7alpha-methoxy-3-tetrazolylthiomethyl-1-dethia-1-oxa-3-cephem-4 -carboxylic acid and its derivative represented by the following formula: ##STR1## (wherein R.sup.1 is alkyl, hydroxyaryl, or thienyl;R.sup.2 and R.sup.4 each is hydrogen, light metal or a carboxy-protecting group; andR.sup.3 is optionally protected hydroxyalkyl, carbamoylalkyl, dialkylaminoalkyl, or sulfamoylalkyl)are disclosed.
    Type: Grant
    Filed: December 6, 1984
    Date of Patent: February 11, 1986
    Assignee: Shionogi & Co., Ltd.
    Inventors: Masayuki Narisada, Fumihiko Watanabe, Yoshio Hamashima
  • Patent number: 4551469
    Abstract: Antifungal and plant growth regulatory compounds of the formula ##STR1## in which R.sub.1 is alkyl, cycloalkyl or optionally substituted phenyl, and R.sub.2 is optionally substituted phenyl or benzyl.
    Type: Grant
    Filed: September 3, 1980
    Date of Patent: November 5, 1985
    Assignee: Imperial Chemical Industries PLC
    Inventors: Keith P. Parry, Paul A. Worthington, William G. Rathmell
  • Patent number: 4551502
    Abstract: Novel complexes are prepared from water-soluble compounds having at least one amidocarbonylic unit and a square planar organometallic compound.
    Type: Grant
    Filed: September 19, 1983
    Date of Patent: November 5, 1985
    Inventors: Bobby A. Howell, Erik W. Walles
  • Patent number: 4544743
    Abstract: This invention relates to new salts of 1,3,5-oxadiazines-2,4,6-triones, to new 1,3,5-oxadiazines-2,4,6-triones and to the preparation thereof.
    Type: Grant
    Filed: June 27, 1983
    Date of Patent: October 1, 1985
    Assignee: Societe Carbochimique
    Inventors: Pierre M. Lambert, Ignacio De Aguirre-Otegui
  • Patent number: 4533730
    Abstract: Intermediates for preparing an antibacterial 1-dethia-1-oxacephalosporins which are represented by the following formula: ##STR1## wherein R is a monovalent group (minus the carbonyl) from an acyl derived from a carboxylic or carbonic acid;Y.sup.1 is a divalent group of the following formula: ##STR2## wherein COB is carboxy or protected carboxy;X is hydrogen or a nucleophilic group; andZ is a leaving groupare prepared from a compound of the following formula; ##STR3## wherein R and Y.sup.1 are as defined above by the action of an acid. The new compounds of this invention shown by the following formula: ##STR4## wherein A is amino or substituted amino;E is hydrogen or methoxy; andY is a divalent group of the following formula: ##STR5## in which COB, X, and Z are as defined above are convertible into other compounds of the same formula by applying conventional methods in .beta.-lactam chemistry.
    Type: Grant
    Filed: October 19, 1983
    Date of Patent: August 6, 1985
    Assignee: Shionogi & Co., Ltd.
    Inventors: Mitsuru Yoshioka, Uyeo Shoichiro, Yoshio Hamashima, Ikuo Kikkawa, Teruji Tsuji, Wataru Nagata
  • Patent number: 4532233
    Abstract: An antibacterial 7.beta.-(fluorinated methylthioacetamido)-7.alpha.-methoxy-3-(1-hydroxyalkyl-5-tetrazolyl)thiom ethyl-1-dethia-1-oxa-3-cephem-4-carboxylic acid and its derivatives at the carboxy or hydroxyalkyl represented by the following formula: ##STR1## wherein, R is FCH.sub.2 -- or F.sub.2 CH--; R.sup.1 is R.sup.3 O-substituted-alkyl in which R.sup.3 is hydrogen or a hydroxy-protecting group; and R.sup.2 is a hydrogen or light metal atom or a carboxy-protecting group, antibacterial drugs containing it, its use and production.
    Type: Grant
    Filed: December 22, 1983
    Date of Patent: July 30, 1985
    Assignee: Shionogi & Co., Ltd.
    Inventors: Teruji Tsuji, Hisao Sato, Yoshio Hamashima
  • Patent number: 4529721
    Abstract: A compound of the formula: ##STR1## wherein u represents hydrogen, carboxamido, N-hydroxycarboxamido, carboxy, azido, an aryl, an acylamino, a protected carboxy or an N-alkoxycarboxamido, or, together with v, can represent --S-- or --CH.sub.2 S--; v represents hydrogen, halogen, cyano or an alkylthio, or, together with u, can represent --S-- or --CH.sub.2 S--, or, together with w, can represent --(CH.sub.2).sub.3 CO--; w represents hydrogen, carboamoyl, cyano, carboxy, an N-alkylcarbamoyl, an alkyl, an aryl, a protected carboxy or a heterocycle, or, together with v, can represents --(CH.sub.2).sub.
    Type: Grant
    Filed: September 21, 1983
    Date of Patent: July 16, 1985
    Assignee: Shionogi & Co., Ltd.
    Inventors: Wataru Nagata, Mitsuru Yoshioka, Yasuhiro Nishitani, Tsutomu Aoki, Toshiro Konoike, Tadatoshi Kubota
  • Patent number: 4515954
    Abstract: This disclosure describes metal chelates of anthracene-9,10-bis-carbonylhydrazones and derivatives thereof useful as antibacterial agents, for inhibiting the growth of transplanted mouse tumors, and for inducing the regression and/or palliation of leukemia and related cancers.
    Type: Grant
    Filed: June 6, 1983
    Date of Patent: May 7, 1985
    Assignee: American Cyanamid Company
    Inventors: Stanley A. Lang, Jr., Keith C. Murdock
  • Patent number: 4489002
    Abstract: Compounds of the general formula I ##STR1## where E is --CH.dbd. or --N.dbd., K is the radical of an amine or of a coupling component of the benzene, naphthalene, pyrazole, pyridine, pyrimidine, quinoline or isoquinoline series, or the radical of a 1,3-dicarbonyl compound which can be coupled, X is --O-- or --COO--, Y is --O--, --COO-- or --NH--, Z.sup.1 and Z.sup.2 independently of one another are unsubstituted or substituted alkyl or cycloalkyl, and one of them may furthermore be unsubstituted or substituted aryl, or Z.sup.1 and Z.sup.2 together with the nitrogen atom are a heterocyclic radical, and Z is unsubstituted or substituted C.sub.2 - or C.sub.3 -alkylene, from 1 to 4 sulfonic acid groups can be present and the rings A and B can be further substituted or can carry a fused benzene ring.The compounds of the present invention are suitable for dyeing or printing natural or synthetic N-containing materials, i.e., wool, leather or polyamide or polyurethane fibers, as wells as for coloring inks.
    Type: Grant
    Filed: June 4, 1982
    Date of Patent: December 18, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Hans Baumann, Klaus Grychtol
  • Patent number: 4478959
    Abstract: Amino and amido carboxylates of divalent tin, zinc, cobalt and nickel which are useful as catalysts for polyurethane formulations. Such compounds correspond to either of the formulae: ##STR1## wherein R.sub.1 and R.sub.2 are independently C.sub.1 -C.sub.20 alkyl, C.sub.6 -C.sub.20 cyclohydrocarbyl, C.sub.2 -C.sub.20 hydroxyalkyl or alkoxyalkyl, or R.sub.1 and R.sub.2 together with N form a nitrogen-containing heterocyclic ring of 5 or 6 atoms;R.sub.3 is a --CH.sub.2).sub.n group where n is an integer from 2 to 6 or a ##STR2## group where R.sub.4 is an alkyl, cycloalkyl or aryl group of up to 6 carbon atoms;A is ##STR3## wherein R.sub.5 and R.sub.6 are independently hydrogen, C.sub.1 -C.sub.4 alkyl or R.sub.5 and R.sub.6 together form part of a six-member cyclohydrocarbyl ring, andM is divalent tin, zinc, cobalt or nickel.
    Type: Grant
    Filed: September 29, 1983
    Date of Patent: October 23, 1984
    Assignee: Air Products and Chemicals, Inc.
    Inventors: Ibrahim S. Bechara, Rocco L. Mascioli
  • Patent number: 4464490
    Abstract: Amino and amido dialkyltin dicarboxylates and stannoxy carboxylates are prepared by first reacting an amine or amino alcohol with a dicarboxylic acid anhydride, followed by reaction of the resulting product with a dialkyltin oxide. The obtained compounds are useful as catalysts for promoting reaction of organic isocyanates with organic compounds having one or more active hydrogen-containing groups.
    Type: Grant
    Filed: March 18, 1983
    Date of Patent: August 7, 1984
    Assignee: Air Products and Chemicals, Inc.
    Inventors: Ibrahim S. Bechara, Rocco L. Mascioli
  • Patent number: 4454135
    Abstract: Novel tetraorganotin benzenesulfonamide compounds are described which possess insecticidal and arachnicidal activity. In addition, novel trifluoroacetate organotin benzenesulfonamide intermediates useful in the synthesis of these tetraorganotin benzenesulfonamide compounds are described.
    Type: Grant
    Filed: January 4, 1983
    Date of Patent: June 12, 1984
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Gerald E. Lepone
  • Patent number: 4430456
    Abstract: Amino and amido dialkyltin dicarboxylates and stannoxy carboxylates are prepared by first reacting an amine or amino alcohol with a dicarboxylic acid anhydride, followed by reaction of the resulting product with a dialkyltin oxide. The obtained compounds are useful as catalysts for promoting reaction of organic isocyanates with organic compounds having one or more active hydrogen-containing groups.
    Type: Grant
    Filed: September 16, 1982
    Date of Patent: February 7, 1984
    Assignee: Air Products and Chemicals, Inc.
    Inventors: Ibrahim S. Bechara, Rocco L. Mascioli
  • Patent number: 4417012
    Abstract: Additives for rubber compositions, giving vulcanisates having improved retention of optimum physical properties, are compounds containing two or more groups of the formula --S--SO.sub.2 R linked by an organic bridging group, or polymers containing two or more groups of the formula --S--SO.sub.2 R attached to an organic polymer chain, where R represents (a) a radical OM where M is a monovalent metal, the equivalent of a multivalent metal, a monovalent ion derived by the addition of a proton to a nitrogenous base, or the equivalent of a multivalent ion derived by the addition of two or more protons to a nitrogenous base, or (b) an organic radical selected from aliphatic, cycloaliphatic, aromatic and heterocyclic radicals, and radicals which are combinations of any two or more such radicals.
    Type: Grant
    Filed: June 30, 1982
    Date of Patent: November 22, 1983
    Assignee: Monsanto Europe S.A.
    Inventor: Philippe G. Moniotte
  • Patent number: 4367304
    Abstract: Compounds of the formula I, II, III or IV ##STR1## wherein X is halogen, OH, --OR.sup.1, --OOCR.sup.2, --OOC--R.sup.4 --COOR.sup.3 or --N(R.sup.5)(R.sup.6), or the two X groups together form a group --O--R.sup.9 --O-- or --OOC--R.sup.9 --COO--, Y has one of the meanings given for X, or it is --NHR.sup.5, --NHNH.sub.2 or --NHNH-phenyl, Z has one of the meanings given for X, or is --SR, and R, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.9 and R' are organic radicals having the meanings defined hereinbelow, are thermal stabilizers for chlorine-containing thermoplastics particularly for PVC. Their effect can be further intensified by the addition of co-stabilizers.
    Type: Grant
    Filed: November 4, 1980
    Date of Patent: January 4, 1983
    Assignee: Ciba-Geigy Corporation
    Inventors: Klaus-Peter Michaelis, Wolfgang Wehner, Holger Andreas, Horst Muller
  • Patent number: 4361579
    Abstract: A polycondensation product of a germanium trihydroxide compound of the formula: ##STR1## wherein W is hydrogen, alkyl, halogen, alkoxycarbonyl, carboxy, aryl, cycloalkyl which may be substituted, cycloalkenyl, heteroaryl or a group of the formula: (R.sup.1)(R.sup.2)N-- wherein R.sup.1 and R.sup.2 are each lower alkyl or R.sup.1 and R.sup.2 together with the adjacent nitrogen atom form a group of the formula: ##STR2## wherein R.sup.3 is hydrogen, lower alkyl, phenyl which may be substituted, aralkyl, acyl, acylamino or heteroaryl, and X is --N.dbd., --CH.dbd. or ##STR3## A is a bond, alkylene, alkenylene, --CO--Y--, --CONH--Y--, --O--Y--, --S--Y-- or ##STR4## (Y is alkylene); and R is alkyl. Such compounds are useful as agents for treating immune diseases.
    Type: Grant
    Filed: September 19, 1980
    Date of Patent: November 30, 1982
    Assignee: Yoshitomi Pharmaceutical Industries, Ltd.
    Inventors: Tomohiko Munakata, Chiaki Tashiro, Yutaka Maruyama
  • Patent number: 4360670
    Abstract: Amino and amido dialkyltin dicarboxylates and stannoxy carboxylates are prepared by first reacting an amine or amino alcohol with a dicarboxylic acid anhydride, followed by reaction of the resulting product with a dialkyltin oxide. The obtained compounds are useful as catalysts for promoting reaction of organic isocyanates with organic compounds having one or more active hydrogen-containing groups.
    Type: Grant
    Filed: February 2, 1981
    Date of Patent: November 23, 1982
    Assignee: Air Products and Chemicals, Inc.
    Inventors: Ibrahim S. Bechara, Rocco L. Mascioli
  • Patent number: 4355161
    Abstract: A new composition of matter comprising molybdenum trioxide and heterocyclic nitrogen or oxygen Lewis bases. The molybdenum trioxide, upon reaction with Lewis base, forms a layered compound characterized in that the Lewis base is covalently bonded to molybdenum atoms in molybdenum oxide layers. The layered compound has the formula LMoO.sub.3 where L is a Lewis base containing nitrogen or oxygen electron donors and selected from the group consisting of 5- and 6-membered heterocyclic amines, amine oxides, triorganophosphates, phosphine oxides and sulfoxides. L has the steric requirement such that its cross-sectional area perpendicular to an axis running through the L-Mo covalent bond is less than about 30(A).sup.2.
    Type: Grant
    Filed: November 10, 1980
    Date of Patent: October 19, 1982
    Assignee: Exxon Research and Engineering Co.
    Inventors: Jack W. Johnson, Allan J. Jacobson
  • Patent number: 4355162
    Abstract: A new composition of matter comprising the reaction product of a mixed oxide having layers of corner linked octahedra and tetrahedra and a Lewis base. The reaction product forms a layered compound of the formula L.sub.x MOM'O.sub.4 where MOM'O.sub.4 is a mixed oxide selected from the group consisting of VOPO.sub.4, VOSO.sub.4, VOAsO.sub.4, VOMoO.sub.4, NbOPO.sub.4, NbOAsO.sub.4, TaOPO.sub.4 and MoOPO.sub.4, x is from about 0.1 to 1.0 and L is a Lewis base containing nitrogen or oxygen electron donor and is selected from the group consisting of 5-membered heterocyclic amines, 6-membered heterocyclic amines, amine oxides, triorganophosphates, phosphine oxides and sulfoxides. The layered compounds are characterized in that L is covalently bound to a metal atom in the MOM'O.sub.4 layer.
    Type: Grant
    Filed: November 10, 1980
    Date of Patent: October 19, 1982
    Assignee: Exxon Research and Engineering Co.
    Inventors: Jack W. Johnson, Allan J. Jacobson
  • Patent number: 4354024
    Abstract: A new composition of matter comprising layered compounds of tungsten trioxide and heterocyclic nitrogen or oxygen Lewis bases which have a unique layered structure. The layered compounds have the formula LWO.sub.3 where L is a Lewis base selected from the group consisting of 5-membered heterocyclic amines, 6-membered heterocyclic amines, amine oxides, triorganophosphates, phosphine oxides and sulfoxides, the layered compounds being characterized in that L is covalently bound to a tungsten atom in the tungsten oxide layer.
    Type: Grant
    Filed: November 10, 1980
    Date of Patent: October 12, 1982
    Assignee: Exxon Research and Engineering Company
    Inventors: Jack W. Johnson, Allan J. Jacobson
  • Patent number: 4339448
    Abstract: New imidazole-copper complex compounds having a good fungicidal action, fungicides containing these compounds as active ingredients, processes for their manufacture, and their use for combating fungi.
    Type: Grant
    Filed: October 22, 1979
    Date of Patent: July 13, 1982
    Assignee: BASF Aktiengesellschaft
    Inventors: Toni Dockner, Anton Frank, Ernst-Heinrich Pommer
  • Patent number: 4321373
    Abstract: This invention relates to 2-hydroxy-3-naphthoic acid amides of the general formula: ##STR1## wherein R.sub.1 is hydrogen, a substituted or unsubstituted alkyl, cycloalkyl, aralkyl, or aryl group, and R.sub.2 and R.sub.3 are identical or different and are hydrogen, a substituted or unsubstituted alkyl, cycloalkyl, aralkyl, or aryl group, or, together with the nitrogen atom to which they are attached, a substituted or unsubstituted heterocyclic group. The compounds are useful as coupling components for diazo printing.
    Type: Grant
    Filed: August 29, 1980
    Date of Patent: March 23, 1982
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Siegfried Scheler
  • Patent number: 4297364
    Abstract: New compounds of the formula ##STR1## which have a good fungicidal action, their manufacture, fungicides containing these compounds as active ingredients, and processes for combating fungi with these compounds.
    Type: Grant
    Filed: October 10, 1979
    Date of Patent: October 27, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Hubert Sauter, Bernd Zeeh, Costin Rentzea, Ernst-Heinrich Pommer
  • Patent number: 4296030
    Abstract: This disclosure describes metal chelates of symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxy-anthraquinones useful for inhibiting the growth of tumors and as colorants or dyes.
    Type: Grant
    Filed: April 9, 1980
    Date of Patent: October 20, 1981
    Assignee: American Cyanamid Company
    Inventors: Stanley A. Lang, Jr., Keith C. Murdock