Abstract: This invention relates to substituted dihydropyridazinones, pyridazinones and related compounds, of the formula ##STR1## wherein A, Q, D and R1 are as defined within, compositions containing these compounds and methods of controlling agricultural and mammalian fungal diseases.

Abstract: The present invention provides anionic polymerization initiators, comprising lithium amino magnesiate complexes, resulting in diene polymer and copolymer elastomers. The invention initiators have stable living ends at high polymerization temperatures and produce polymers containing a high level of tertiary amine functionality. Such polymers exhibit an increased efficiency in coupling termination reactions, and elastomers and products prepared from such polymers exhibit reduced hysteresis properties. Methods are also provided for preparing the initiators, the polymers and the elastomers.

Abstract: Novel pyrazole-containing compounds useful as light-stabilizers for polymers, their Ni, Zn, Cu, and Co metal complexes, and methods for the synthesis of such complexes are provided. The compounds include a hindered amine light stabilizer (HALS) such as a substituted piperidine, thereby incorporate the properties of UV absorbers and redical scavengers. The compounds are of the formulas I and II, ##STR1## where R.sub.1 is phenyl, R.sub.2 is methyl, X is oxygen or sulphur, Z is oxygen or N-aryl, and R.sub.3 is hydrogen, alkyl, a derivative of carboxyacryloyl or carboxybenzoyl or a derivative of pyrazole. The compounds and their metal complexes are highly compatible with various polymers, thermostable, and retain their photostability under conditions of continuous and intensive irradiation. Methods for the synthesis of metal complexes include the reaction of: (a) a compound with metal acetate; or (b) a metal complex with anhydride or a pyrazole derivative.

Abstract: Heterocyclic chelating agents and salts thereof of formula I: ##STR1## wherein X represents a bond, O or S, or a group CHR.sup.1 or NR.sup.3 ; each R.sup.1 represents H, a group OR.sup.3 or NR.sup.3 R.sup.3, or an alkyl or alkoxyalkyl group optionally substituted by a hydroxyl group or by a group NR.sup.3 R.sup.3 or CON.sup.3 R.sup.3 ;each R.sup.2 represents H, or an alkyl or alkoxy group optionally substituted by a hydroxyl or alkoxy group;each R.sup.3 represents H, an optionally hydroxylated alkyl group or a group CH.sub.2 Y;Y represents a group COZ, CON(OH)R.sup.4, POZ.sub.2 or SO.sub.2 Z,Z represents a group OR.sup.4, NR.sup.4 R.sup.4 or ##STR2## where each R.sup.11 is H, a hydroxyl group or an optionally hydroxylated alkyl group, s is 0, 1 or 2, and W is CHR.sup.11, NR.sup.11 or an oxygen atom; andeach R.sup.4 represents H, or an optionally mono- or poly-hydroxylated alkyl, alkoxyalkyl or polyalkoxyalkyl group;with the provisos that where s is 0 then W is CHR.sup.

Abstract: An anionic initiator system formed by the reaction product of: (1) an organolithium compound with (2) the reaction product of (a) a secondary amine and (b) diisopropenyl benzene, initiates polymerization to produce a polymer containing tertiary amine functional sites incorporated at the head of the polymer chain. A subclass of these polymers can be compounded to exhibit reduced hysteresis over conventionally prepared polymers.

Abstract: Compounds of formula (I): ##STR1## in which: A and B are separately monoamines or together diamines; and Z is a group of formula (II) or (III): ##STR2## (in which R.sup.1, R.sup.2 and R.sup.7 are various organic groups, n is 0, 1 or 2 and X is a direct carbon-carbon bond or lower alkylene) show valuable anti-tumor activity and may be prepared by reacting an amine-platinum complex with a compound providing the group represented by Z.

Abstract: Novel bis(platinum) (IV) complexes coupled via diamine bridging agents are taught as well as methods for their preparation. These complexes are to be used as pharmaceutical agents, e.g., for the treatment of cancer and parasitic diseases.

Abstract: Water-soluble complexes having the formula: ##STR1## and stereoisomers thereof, where Z.sup.1 and Z.sup.2 are halogens, and X.sup.1 and X.sup.2 are selected from the group consisting of sulfate, phosphate, nitrate, and monocarboxylate, or are jointly dicarboxylate, have been found to have desirable antitumor activity, as well as relatively low levels of toxicity.

Abstract: Titanocenes of the formula I ##STR1## in which R.sup.1 are cyclopentadienyl.sup..crclbar. groups and R.sup.2 and R.sup.3 are aromatic radicals which are substituted in both ortho-positions by fluorine and, in addition, are substituted by an acyloxy group are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated compounds.

Abstract: A ferrocene derivatives represented by the following formula (I): ##STR1## can be a useful ligand to metals with Lewis acidity and is used as a catalyst for asymmetric synthesis with good enantioselectivity. This ferrocene derivatives is synthesized from a novel haloferrocene derivative represented by formula (II) and the haloferrocene derivative is synthesized from a novel ferrocene derivative represented by formula (III).

Abstract: Titanocenes of the formula I ##STR1## in which R.sup.1 are cyclopentadienyl.sup..crclbar. groups and R.sup.2 and R.sup.3 are aromatic radicals which are substituted in both ortho-positions by fluorine and, in addition, are substituted by an acyloxy group are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated compounds.

Abstract: Comounds having the formula ##STR1## wherein: a is 2 or 3; b is an integer from 0 to 4;Me.sup.(a+) is an ion of an element of atomic number from 57 to 70 or an ion of a transition metal of atomic number 21-29, 42 or 44;E.sup.(b+) is one or more physiologically biocompatible cation of an inorganic or an organic base or amino acid, said cation representing a total positive charge of b units;S is the group --A--O--R wherein:A is --(CH.sub.2).sub.m --; --CH.sub.2 --C(CH.sub.3).sub.2 --; m is an integer from 1 to 5; R is H; linear or branched alkyl of 1 to 8 carbon atoms, said carbon atoms being unsubstituted or substituted by one or more hyroxy group; aralkyl of 1 to 4 aliphatic carbon atoms; phenyl or phenyl substituted by halogen, amino, hydroxy or trifluoromethyl; (poly)-oxa-alkyl of 1 to 10 oxygen atoms and from 3 to 30 carbon atoms;R.sub.1 is R.sub.2 or --CH.sub.2 COOZ; --CH(CH.sub.3)COOZ; --(CH.sub.2).sub.n --N(CH.sub.2 COOZ).sub.

Abstract: Disclosed herein is a class of chiral copper-amine complexes of the formula R(L*) CuLi in which L* is selected from: ##STR1## In this formula, R is a transferable ligand, which can be alkyl, aryl or aralkyl. M is a metal ion such as Li, Na, K, Cs, Rb, Be, Mg and other metal ions from the first two columns of the periodic table. R.sub.1 is straight chain alkyl, R.sub.2 is aryl or substituted aryl and R.sub.3 and R.sub.4 form a heterocyclic ring or a substituted heterocyclic ring with 4 to 8 members including oxygen and sulfur.Such complexes react with .alpha.,.beta.-unsaturated ketones, aldehydes, esters and other carbonyl containing compounds such that R is transferred to the 3 position enantioselectively as shown below. ##STR2## Such complexes react with .alpha.,.beta.-unsaturated ketones in the presence of trialkysilyl halides to give silyl enol ether in which R is substituted in the 3 position as shown below.

Abstract: A ferrocene derivatives represented by the following formula (I): ##STR1## can be a useful ligand to metals with Lewis acidity and is used as a catalyst for asymmetric synthesis with good enantioselectivety. This ferrocene derivatives is synthesized from a novel haloferrocene derivative represented by formula (II) and the haloferrocene derivative is synthesized from a novel ferrocene derivative represented by formula (III).

Abstract: Platinum complexes of the general formula I[(R.sup.1 NH.sub.2).sub.n Pt].sub.q Y.sub.m X.sub.p (I)in which Y is a phosphonic acid ligand, and the preparation thereof, are described. The platinum complexes are suitable as active substances in pharmaceuticals, in particular for controlling cancers.

Abstract: This disclosure sets forth a novel process for producing cisplatin analogs which possess antitumor activity.

Abstract: A platinum complex of the formula ##STR1## wherein n is 1 or 2 and X is chlorine, bromine or iodine is described, which is useful intermediate; thus, it can be reacted with silver nitrate or silver sulfate and the resulting compound can be treated with an anion exchange resin or barium hyroxide to give a compound of the formula ##STR2## which can then be reacted with glycolic acid to furnish a compound of the formula ##STR3## wherein n is 1 or 2 and A is --OCOCH.sub.2 O--; these products are useful antineoplastic agents.

Abstract: Titanocenes with silylated .pi.-cyclopentadienyl ligands in which one or two carbo- or heterocyclic aromatic rings are bonded to the titanium, the aromatic rings being substituted by fluorine, --CF.sub.3, --C.sub.2 F.sub.5, --CF.sub.2 CL or --CF.sub.2 CH.sub.3 in at least one of the two ortho-positions relative to the metal-carbon bonds, are suitable as photoinitiators for the photopolymerization of ethylenically unsaturated substrates. They are distinguished by a high sensitivity, stability to air and the action of heat, and a high activity in the region of UV light to visible light. They are furthermore readily soluble in the photopolymerizable compositions.

Abstract: Methods and apparatus for the extraction of a ligand such as molecular oxygen from a first fluid environment and for release of a ligand such as molecular oxygen, as well as ligand carrier compounds therefor comprising linear, pentadentate polyalkylamines and transition metal ions. The carrier compounds have the general formula: ##STR1## where, each of R.sub.1 and R.sub.2 is independently an organic group including a sulfur, an oxygen or a nitrogen coordinated to M;each of m, n, o, and p is 1, 2, 3, or 4;X is selected from the group consisting of 2,6-pyridyl, 2,6-piperidyl, 2,5-pyrrolyl, 2,4-imidazolyl, substituted heterocyclic amines, --)--, --S--, ##STR2## and ##STR3## where R.sub.3 is hydrogen, lower alkyl or aralkyl; and M is a transition metal ion.

Abstract: Novel platinum complex of the formula: ##STR1## wherein n is an integer of 1 or 2 and A is a ligand of the formula: ##STR2## which has excellent antineoplastic activity and is useful as an antineoplastic agent for the treatment of various malignant tumors, and a pharmaceutical composition containing the platinum complex as an active ingredient, and an intermediate for preparing the compound.

Abstract: This disclosure sets forth a novel process for producing cisplatin analogs which possess antitumor activity.

Abstract: Complexes of platinum II containing a single radiosensitizer ligand and an amino or ammine substituent shows superior binding to DNA and are useful in chemotherapy and sensitization of hypoxic tumors to radiation. The chemotherapeutic value of these compounds is enhanced by administration of vasoactive agents.

Abstract: Compounds suitable for NMR imaging having the formula: ##STR1## wherein a is 2 or 3;b is an integer from 0 to 4;Me.sup.(a+) is Fe.sup.(2+), Fe.sup.(3+), Gd.sup.(3+), or Mn.sup.(2+) ;E.sup.(b+) is an ion of an alkali metal, alkaline earth metal, alkyl ammonium, alkanol ammonium, polyhydroxyalkyl ammonium, or basic protonated amino acid, said ions representing a total charge of b;m is an integer from 1 to 5;R is H, alkyl with from 1 to 8 carbon atoms, alkyl with from 1 to 8 carbon atoms wherein from 1 to 5 carbons are substituted with OH; aralkyl with 1 to 4 aliphatic carbon atoms; phenyl or phenyl substituted by halogen, hydroxyl, carboxyl, carboxamide, ester, SO.sub.3 H, sulfonamide, lower alkyl, lower hydroxy alkyl, amino, acylamino; (poly)oxa-alkyl with 1 to 50 oxygen atoms and from 3 to 150 carbon atoms, wherein 1 to 5 hydrogen atoms may be substituted by OH;R.sub.1 is the same as R.sub.2 oris --CH.sub.2 COOZ, --CH(CH.sub.3)COOZ, CH.sub.2 CH.sub.2 --N(CH.sub.2 COOZ).sub.

Abstract: Preparation of ethylene copolymers from ethylene and polar and/or non-polar comonomers in the presence of selected nickel-containing catalysts.

Abstract: A compound of the formula (I): ##STR1## (wherein R is C.sub.1 -C.sub.6 alkyl, hydroxy, carboxy, C.sub.1 -C.sub.6 alkoxy, halogen or oxo; m is an integer from 2 to 7; X and Y each is chlorine or nit-rato ligand, or taken together form --OCOCH(R.sup.1)O--, OCOCOO--, ##STR2## R.sup.1 is hydrogen, C.sub.1 -C.sub.5 alkyl, hydroxymethyl, halogmethyl or phenyl; R.sup.2 is hydrogen or C.sub.1 -C.sub.5 alkyl; and n is an integer from 2 to 5), being useful as antitumor agents is provided.

Abstract: Zinc compounds of formula IICF.sub.3 CCl.sub.2 ZnCl.cndot.yL (II)wherein y is 1 or 2 and L is a solvent ligand selected from the group of the N-disubstituted acid amides, N-substituted lactams and the organic sulfoxides, are suitable for reaction with CO.sub.2, COS or SO.sub.2 to give, after working up, the acids of formula ICF.sub.3 CCl.sub.2 --X (I)wherein X is --CO.sub.2 H, --CSOH or --SO.sub.2 H, in good yield.

Abstract: Organic platinum complexes active as anti-tumor agents in warm-blooded animals, and methods for synthesis of same, are described.

Abstract: Tetrazole intermediates useful to prepare antihypertensive compounds described in coassigned application U.S. Ser. No. 884,920, filed July 11, 1986, are described, these tetrazoles have the formula: ##STR1## wherein X.sup.1 and X.sup.2 are as described in the specification.

Abstract: A method of combating fungi or regulating the growth of plants which comprises applying to such fungi, such plants or to a fungus or plant growth situs an amount effective therefor of an imidazo-pyrrolo-pyridine of the formula ##STR1## in which R.sup.1 represents cyano, alkoxycarbonyl or aminocarbonyl,R.sup.2 represents hydrogen, alkyl, trimethylsilyl or one equivalent of a metal cation andR.sup.3 and R.sup.4 independently of one another each represent alkyl, cycloalkyl or cycloalkylalkyl orR.sup.3 and R.sup.4 together represent a divalent alkanediyl radical.Many of the compounds are new.

Abstract: A ruthenium-phosphine complex represented by formula (I): ##STR1## wherein R represents a hydrogen atom, a methyl group, or a methoxy group; S represents a tertiary amine; when y is 0, then x is 2, z is 4, and p is 1; and when y is 1, then x is 1, z is 1, and p is 0. The complex is inexpensive and exhibits excellent performance as a catalyst for various organic syntheses, and particularly asymmetric hydrogenation.

Abstract: This disclosure describes platinum complexes of heterocyclic-1,2-diamines which possess the property of inhibiting the growth of tumors in mammals.

Abstract: A ruthenium-phosphine complex represented by the formula (I)Ru.sub.x H.sub.y Cl.sub.z (R--BINAP).sub.2 (S).sub.p (I)wherein R--BINAP represents tertiary phosphine represented by the formula (II) ##STR1## R which is the same represents hydrogen, methyl or t-butyl, S represents tertiary amine, y represents 0 or 1, and when y is 0, x represents 2, z represents 4 and p represents 1, and when y is 1, x represents 1, z represents 1 and p represents 0.

Abstract: Titanocenes containing .pi.-cyclopentadienyl ligands, in which one or two carbocyclic or heterocyclic aromatic rings are attached to the metal atom, said aromatic rings being substituted by fluorine in at least one of the two ortho-positions relative to the metal-carbon bonds, are suitable photoinitiators for the photopolymerization of ethylenically unsaturated substrates. They are distinguished by high sensitivity, stability to air and heat, and are very effective in the range from UV light to visible light.

Abstract: Novel complexes are prepared from water-soluble compounds having at least one amidocarbonylic unit and a square planar organometallic compound.

Abstract: Vinyl-tin compounds in which one of the carbon atoms of the vinyl moiety is bonded to the nitrogen atom of a nitrogen-containing moiety, useful for controlling invertebrate pests.

Abstract: Preparation of zeolites having the formula:(1.5.+-.0.6) M.sub.2/n O.Al.sub.2 O.sub.3.ySiO.sub.2.zH.sub.2 O[wherein y ranges from 20 to 90, z ranges from 2 to 12, M is at least one cation and n is the valence of M], comprising the admixing of diethyl-piperidinium hydroxide, or a salt thereof, with H.sub.2 O and with at least one Na compound, one Al compound and one Si compound, the molar ratios (ratios of oxides) being:SiO.sub.2 :Al.sub.2 O.sub.3 =from 20 to 120;H.sub.2 O:Na.sub.2 O=from 50 to 600;Na.sub.2 O:SiO.sub.2 =from 0.07 to 0.50;(DEPP).sub.2 O:SiO.sub.2 =from 0.05 to 0.50.The invention concerns also the thus obtained zeolites and their use for acid-catalyzed conversions of hydrocarbons.

Abstract: A new composition of matter comprising molybdenum trioxide and heterocyclic nitrogen or oxygen Lewis bases. The molybdenum trioxide, upon reaction with Lewis base, forms a layered compound characterized in that the Lewis base is covalently bonded to molybdenum atoms in molybdenum oxide layers. The layered compound has the formula LMoO.sub.3 where L is a Lewis base containing nitrogen or oxygen electron donors and selected from the group consisting of 5- and 6-membered heterocyclic amines, amine oxides, triorganophosphates, phosphine oxides and sulfoxides. L has the steric requirement such that its cross-sectional area perpendicular to an axis running through the L-Mo covalent bond is less than about 30(A).sup.2.

Abstract: A new composition of matter comprising layered compounds of tungsten trioxide and heterocyclic nitrogen or oxygen Lewis bases which have a unique layered structure. The layered compounds have the formula LWO.sub.3 where L is a Lewis base selected from the group consisting of 5-membered heterocyclic amines, 6-membered heterocyclic amines, amine oxides, triorganophosphates, phosphine oxides and sulfoxides, the layered compounds being characterized in that L is covalently bound to a tungsten atom in the tungsten oxide layer.

Abstract: This disclosure describes metal chelates of symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxy-anthraquinones useful for inhibiting the growth of tumors and as colorants or dyes.

Abstract: This invention relates to novel phosphoramidates of the formula: ##STR1## wherein R.sup.1 is hydrogen, alkyl, cycloalkyl, or optionally substituted aralkyl, aryl, pyridyl, pyridylmethyl, pyridylethyl or pyrazinyl;R.sup.2 is hydrogen provided R.sup.1 is other than optionally substituted aryl; alkyl; cycloalkyl; alkoxyalkyl; alkylthioalkyl; cyanoalkyl; alkenyl; optionally substituted aralylky; or optionally substituted aryl, provided R.sup.1 is other than hydrogen;R.sup.1 and R.sup.2 taken together with the nitrogen to which they are attached form an optionally substituted morpholino or piperidino group;R.sup.3 is hydrogen, alkyl, cycloalkyl, alkenyl, or optionally substituted aralkyl or aryl;R.sup.4 is (C.sub.1 -C.sub.6) alkyl;R.sup.5 is (C.sub.3 -C.sub.4) alkyl; andX, Y and Z are independently oxygen or sulfur;the agronomically acceptable metal salts and metal salt complexes thereof; and to methods of using them to control nematodes.

Abstract: A Process is disclosed for the preparation of zeolite ferrierite of high purity by hydrothermal crystallization from a starting mixture containing at least one compound selected from piperidine and alkyl-substituted piperidines.

Abstract: The invention relates to metal salts of hydroxybenzoic acids which are complexed with a 4-amino-polyalkylpiperidine derivative or to mixed metal salts of a hydroxybenzoic acid and a polyalkylpiperidine carboxylic acid which may be complexed or not with an 4-amino-polyalkylpiperidine. The metal cation may be that of a di- or trivalent metal such as Ni, Co, Al, Zn or Ca. From hydroxybenzoic acids the 3,5-di-tert.butylbenzoic acid is preferred.These salts are valuable light stabilizers for plastics, especially for polyolefins, styrene polymers and polyamides or polyurethanes respectively. The salts show a strong tendency to retain water. For high compatibility with plastics a low water content is of importance.

Abstract: Novel compounds of the general formula I ##STR1## wherein M.sup.q.sym. is a metal ion carrying a double or triple positive charge and q is 2 or 3 and r is 1 or 2, the quotient q/r being 1, 1.5, 2 or 3, and L is a piperidine which is substituted by at least one enolate group in the 1-position or 4-position and wherein the ring nitrogen is sterically hindered by alkyl substituents in the adjacent positions, and m is 0, 1 or 2 and A is H.sub.2 O or an amine.

Abstract: A process for the preparation of pyrrolidone-5-carboxylic acid/metal salt/amine complexes by reacting 1 mol of a L-glutamic acid lower alkyl ester/metal salt complex with 1 mol of an aliphatic, cycloaliphatic or aromatic-aliphatic damine or 2 mols of an aliphatic or cycloaliphatic monoamine in a polar solvent, with the elimination of 2 mols of alcohol.The complex compounds prepared according to the invention are valuable curing agents for epoxide resins.

Abstract: Nickel complexes containing ortho- or para-hydroxybenzoate anions and a non-ionic amine ligand are valuable light-stabilizers for polymers, particularly for polyolefins. The complexes may also contain a second carboxylate anion, different from the benzoate anion, and in this case also the amine-free nickel compounds show a high stabilizing action.

Abstract: 1,2,3-Thiadiazole-2-id-derivative of the formula ##STR1## in which R.sub.1 is hydrogen or alkyl which may be substituted in one or several places by oxygen or sulfur and wherein R.sub.1 has the meaning as given in the attached specification and wherein X is oxygen or sulfur and B is a univalent metal atom. The compounds have properties suited for controlling the natural growth and natural development of plants and in addition have a superior defoliating property.

Abstract: A single stage process is provided for the direct synthesis of mixed polyimino derivatives of aluminium and alkaline earth metals consisting of reacting aluminium, an amine, the alkaline earth metal or hydride or amide derivative thereof, in the presence of hydrogen, the reaction being promoted by an activator in either hydrocarbon or ether solvents.

Abstract: Process for the homogeneous catalytic hydrogenation of .beta.-substituted-.alpha.-acylamido-acrylic acids which yields, after hydrogenation, an optically active mixture. The process comprises the hydrogenation of .beta.-substituted-.alpha.-acylamido-acrylic acids in the presence of an optically active coordinated metal complex hydrogenation catalyst, in which the metal is selected from the group consisting of rhodium, iridium, ruthenium, osmium, palladium and platinum.This process is a generalized process for any asymmetric hydrogenation of .beta.-substituted-.alpha.-acylamido-acrylic acids in which one .alpha.-amino acid enantiomorph is the desired end-product. It is especially useful for the preparation of .alpha.-amino acids found in nature which possess optical activity and which have a hydrogen attached to the asymmetric center.This invention also relates to new optically active coordinated metal complex hydrogenation catalysts.

Abstract: A process of manufacturing sodium lactamoaluminates by reacting an excess of a lactam in an aromatic hydrocarbon with at least one compound selected from sodium tetrahydridoaluminate, trisodium hexahydridoaluminate, sodium dihydrido-bis(2-methoxyethoxo)aluminate, and sodium tetraamidoaluminate.