Phosphorus Attached Directly To The Six-membered Hetero Ring By Nonionic Bonding Patents (Class 546/21)
  • Patent number: 4259492
    Abstract: Compounds of the formula I ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.18 alkyl,R.sub.2 is hydrogen or C.sub.1 -C.sub.18 alkyl, andA is a substituted primary or secondary aliphatic or alicyclic, aromatic or araliphatic amine, in which the substituents are identical or different, a heterocyclic amine or a hydrazine derivative.
    Type: Grant
    Filed: May 18, 1979
    Date of Patent: March 31, 1981
    Assignee: Ciba-Geigy Corporation
    Inventor: Michael Rasberger
  • Patent number: 4250314
    Abstract: Adducts of alkylphosphorous triamides with alpha, beta-unsaturated carbonyl compounds provide novel sulfur-free load-carrying additives for various organic compositions, e.g., lubricant oils.
    Type: Grant
    Filed: April 30, 1979
    Date of Patent: February 10, 1981
    Assignee: Mobil Oil Corporation
    Inventor: Abraham O. Okorodudu
  • Patent number: 4235809
    Abstract: This invention relates to the preparation of .alpha.-amino phosphonic acids by the direct addition of phosphorous acid to imines.
    Type: Grant
    Filed: August 12, 1976
    Date of Patent: November 25, 1980
    Assignee: Petrolite Corporation
    Inventor: Derek Redmore
  • Patent number: 4232010
    Abstract: A phosphonic acid ester of the formula: ##STR1## and R is a lower alkyl, exhibits a calcium-antagonistic activity. Pharmaceutical compositions containing the same are useful in prophylaxis and treatment of ischemic heart diseases such as angina pectoris, myocardial, infarction, etc. and hypertension.
    Type: Grant
    Filed: May 14, 1979
    Date of Patent: November 4, 1980
    Assignee: Kanebo, Ltd.
    Inventors: Goro Tsukamoto, Koichiro Yoshino, Tominori Morita, Takashi Nose, Mitsuo Okazaki
  • Patent number: 4228109
    Abstract: This invention relates to aliphatic phosphorous containing compounds which are useful as herbicides. Additionally, they demonstrate tolerance towards desired, crops, e.g. wheat and rice.
    Type: Grant
    Filed: August 1, 1978
    Date of Patent: October 14, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Richard F. Sauers
  • Patent number: 4225521
    Abstract: This invention relates to phosphorus containing compounds which are useful as herbicides.Additionally, they demonstrate tolerance towards desired crops, e.g., cotton, soybeans and sugarbeets.
    Type: Grant
    Filed: August 1, 1978
    Date of Patent: September 30, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Richard F. Sauers
  • Patent number: 4217312
    Abstract: This invention relates to phosphorus containing compounds which are useful as herbicides.Additionally, they demonstrate tolerance towards desired crops, e.g., cotton, soybeans and sugarbeets.
    Type: Grant
    Filed: August 1, 1978
    Date of Patent: August 12, 1980
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Richard F. Sauers
  • Patent number: 4196090
    Abstract: Hydrocarbylpoly(oxyalkylene) aminophosphorylamido esters are monoesters and diesters of polyether alcohols and phosphoramidic acids. The esters find use as lubricating oil additives which impart lubricity to the oil.
    Type: Grant
    Filed: September 5, 1978
    Date of Patent: April 1, 1980
    Assignee: Chevron Research Company
    Inventor: Jennifer E. Lilburn
  • Patent number: 4187378
    Abstract: This invention relates to the preparation of pyridyl-4-phosphonates by reacting phosphite ester salts with pyridines which are N-substituted with sterically hindering or "bulky" groups such as "bulky" phenyl groups, for example trityl, .phi..sub.3 C-.
    Type: Grant
    Filed: December 15, 1975
    Date of Patent: February 5, 1980
    Assignee: Petrolite Corporation
    Inventor: Derek Redmore
  • Patent number: 4186268
    Abstract: New mercaptoacylpyrrolidine- and mercaptoacylpiperidine phosphonic acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: January 29, 1979
    Date of Patent: January 29, 1980
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Edward W. Petrillo, Jr.
  • Patent number: 4163850
    Abstract: Quaternary nitrogen-heterocyclic phosphonates wherein the phosphonate group is ortho- or para- to the nitrogen heterocyclic group, where the compounds are characterized as follows: ##STR1## wherein the dotted line represents a cyclic structure which cyclic structure may be the sole cyclic structure, or may be attached to other cyclic groups, where R is a hydrocarbon or a substituted hydrocarbon group such as alkyl, aryl, alkaryl, aralkyl, etc., and X is an anion such as halogen, a sulfite, a sulfate, a sulfonate-containing group, etc.These nitrogen-heterocyclic phosphonates are prepared by reacting an aromatic nitrogen-heterocyclic compound, wherein the nitrogen atom is in the form of a quaternary alkoxy derivative (N--OR hereinafter defined) with a phosphite salt, preferably in the form of an ester of the phosphite, as exemplified by the following equation: ##STR2## Quaternaries of these compounds are prepared by further reaction with a quaternizing agent.
    Type: Grant
    Filed: December 15, 1977
    Date of Patent: August 7, 1979
    Assignee: Petrolite Corporation
    Inventor: Derek Redmore
  • Patent number: 4162280
    Abstract: Preparation of a phosphorylated amidine of the formula ##STR1## wherein X is oxygen or sulfur and R, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are various organic radicals, which comprises reacting a phosphoric acid ester-amide of the formula ##STR2## with a carboxamide of the formula ##STR3## at a temperature between about 0.degree. and 50.degree. C., and then reacting the mixture with a base. Advantageously the reaction is effected at about 0.degree. to 15.degree. C. in the presence of an aliphatic or aromatic optionally chlorinated hydrocarbon or an alcohol as an inert solvent, and in the presence of a catalyst.
    Type: Grant
    Filed: March 17, 1978
    Date of Patent: July 24, 1979
    Assignee: Bayer Aktiengesellschaft
    Inventor: Eckart Kranz
  • Patent number: 4159324
    Abstract: O-(1-Fluoro-2-halo-ethyl)(thiono)phosphoric(phosphonic) acid ester-amides of the formula ##STR1## in which R and R.sup.1 independently represent hydrogen, alkyl, haloalkyl or cyanoalkyl, orR and R.sup.1 conjointly with the nitrogen atom form a heterocyclic ring which can optionally be interrupted by further hetero-atoms,R.sup.2 represents ##STR2## alkoxy, halogenalkoxy or alkyl, Hal represents chlorine or bromine, andX represents oxygen or sulphur, which possess insecticidal acaricidal and nematocidal properties.
    Type: Grant
    Filed: June 15, 1977
    Date of Patent: June 26, 1979
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter Arlt, Hellmut Hoffmann, Bernhard Homeyer, Wolfgang Behrenz, Ingeborg Hammann
  • Patent number: 4144394
    Abstract: Compounds of the formulas ##STR1## WHEREIN: X represents oxygen or sulfur;Z represents the residue of a hydroxyl-containing moiety;R.sub.1 and R.sub.2 in formula (1) may be the same or different and individually represent alkyl, cycloalkyl or aryl and, together with the common nitrogen atom, represent a 5 or 6-member ring containing oxygen, sulfur or nitrogen or combination thereof;Nr.sub.1 r.sub.2 in formula (2) represent a 5 or 6-member ring containing oxygen, sulfur or nitrogen or combination thereof;N represents an integer having a value of 2 or greater and is equal to the number of hydroxyl groups on the original hydroxyl-containing moiety,Are prepared by reacting a phosphorohalidate with an amine in an organic solvent containing aqueous alkali metal or ammonium hydroxide.The compounds are useful as flame retardants for natural and synthetic materials.
    Type: Grant
    Filed: December 19, 1977
    Date of Patent: March 13, 1979
    Assignee: Monsanto Company
    Inventors: Albert W. Morgan, Ignatius Schumacher, William Vanderlinde
  • Patent number: 4140774
    Abstract: Compounds of the formula ##STR1## in which R represents halogen, C.sub.1 -C.sub.6 -alkyl, C.sub.1 -C.sub.3 -haloalkyl, C.sub.1 -C.sub.2 alkoxy, NO.sub.2 or S-CH.sub.3, R.sub.1 represents hydrogen or C.sub.1 -C.sub.6 -alkyl, R.sub.2 represents C.sub.1 -C.sub.6 -alkylamino, C.sub.3 -C.sub.8 -alkenylamino, N,N-di-(C.sub.1 -C.sub.6 -alkylamino), C.sub.5 -C.sub.8 -cycloalkylamino or a saturated N-heterocycle having from 4 to 8 C-atoms altogether of which 1 or 2 may stand in the side chain and in which one CH.sub.2 group of the cycle may be replaced by oxygen or sulfur, R.sub.3 represents C.sub.1 -C.sub.6 -alkyl, X is oxygen or sulfur and n is zero or a whole number in the range of from 1 to 3 exhibit a good herbicidal effect on some economically important weed grasses and dicotyledonous weeds and simultaneously they have excellent insecticidal and acaricidal properties.
    Type: Grant
    Filed: February 2, 1977
    Date of Patent: February 20, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gerhard Salbeck, Hubert Schonowsky, Gerhard Horlein, Hermann Bieringer, Peter Langeluddeke, Ludwig Emmel, Anna Waltersdorfer
  • Patent number: 4124588
    Abstract: Anti-allergic 4-hydroxy-3-quinoline-2-one-3-phosphonic acid esters are prepared by reacting an isatoic anhydride with the carbanion resulting from the treatment of phosphono acetic acid alkyl esters with a proton abstracting agent.
    Type: Grant
    Filed: March 1, 1976
    Date of Patent: November 7, 1978
    Assignee: Sandoz, Inc.
    Inventors: Goetz E. Hardtmann, Gary M. Coppola
  • Patent number: 4124400
    Abstract: Compounds of the formula ##STR1## wherein: Z represents a radical selected from the group consisting of alkyl or aryl radicals;R.sub.1 and R.sub.2 may be the same or different and individually represent a radical selected from the group consisting of alkyl, cycloalkyl or aryl radicals; andR.sub.1 and R.sub.2 together with their common nitrogen atom represent a heterocyclic ring,Impart flame retardant properties to natural and synthetic polymers.
    Type: Grant
    Filed: May 9, 1977
    Date of Patent: November 7, 1978
    Assignee: Monsanto Company
    Inventors: Albert W. Morgan, Ignatius Schumacher, William Vanderlinde