Patent number: 6534545
Abstract: 6-tert-Butyl-1,1-dimethylindane derivatives which are unsaturated in the 4-position of formula:
X represents:
(i) either a radical of formula: (a)
and Y represents a radical of formula: (b)
(ii) or a radical of formula: (c)
and Y represents either a radical of formula (b) or a radical of formula:
Z being —O—, —S— or
R1 represents —CH3, —(CH2)p—OR4, —(CH2)p—COR5 or —S(O)t—R6,
p being 0, 1, 2 or 3, t being 0, 1 or 2, R2 represents H or lower alkyl, R3 represents H, lower alkyl or —COR7, R4 represents H, lower alkyl, —COR7, aryl, aralkyl, mono- or polyhydroxyalkyl, or a polyether radical, R5 represents H, lower alkyl, —OR8 or —N(r′)(r″), R6 represents H or lower alkyl, R7 represents lower alkyl, R8 represents H, alkyl, alkenyl, alkynyl, aryl, aralkyl, mono- or polyhydroxyalkyl, a sugar residu
Type:
Grant
Filed:
May 26, 2000
Date of Patent:
March 18, 2003
Assignee:
Galderma Research & Development
Inventors:
Angel De Lera, Beatriz Dominguez