Having -c(=x)-, Wherein X Is Chalcogen, Bonded Directly To The Piperidine Ring Patents (Class 546/245)
  • Reduction of blood pressure with carboxyalkylacyl-pipecolic acid derivatives
    Patent number: 4128653
    Abstract: New carboxyalkylacylamino acids which are derivatives of proline, pipecolic acid and azetidine-2-carboxylic acid and have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
    Type: Grant
    Filed: February 11, 1977
    Date of Patent: December 5, 1978
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: David W. Cushman, Miguel A. Ondetti
  • Process for the preparation of carboxylic acid amides from organic halides
    Patent number: 4128554
    Abstract: Carboxylic acid amides are obtained from aryl, heterocyclic, and vinylic halides and substituted derivates thereof, by reacting same with a primary or secondary amine and carbon monoxide, in the presence of a palladium catalyst and if necessry a tertiary amine at about 20.degree.-150.degree. C and from at least a half atmosphere pressure.
    Type: Grant
    Filed: March 10, 1977
    Date of Patent: December 5, 1978
    Assignee: University of Delaware
    Inventor: Richard F. Heck
  • Carbamoyloxy acrylate compounds
    Patent number: 4126747
    Abstract: Unsaturated carbamoyloxy carboxylates having low color are produced by reacting hydroxyalkyl carbamates such as N-methyl 2-hydroxyethyl carbamate with acrylic or methacrylic acid in contact with a lower alkoxy substituted phenolic or alkylated alkoxyphenolic polymerization inhibitor at a critical low reaction temperature of 40.degree. C. to 80.degree. C. Novel unsaturated carbamoyloxy carboxylates are also disclosed.
    Type: Grant
    Filed: December 28, 1976
    Date of Patent: November 21, 1978
    Assignee: Union Carbide Corporation
    Inventors: Frank G. Cowherd, III, Louis F. Theiling, Jr.
  • Isoxazolylmethylthiol carbamates
    Patent number: 4124591
    Abstract: Isoxazolylmethylthiol carbamates, herbicides containing these compounds, and methods of controlling the growth of unwanted plants with these compounds.
    Type: Grant
    Filed: June 27, 1977
    Date of Patent: November 7, 1978
    Assignee: BASF Aktiengesellschaft
    Inventors: Karl Eicken, Hans Theobald, Hanspeter Hansen, Bruno Wuerzer, Kurt Fett