Polycyclo Ring System Having The 1,3-diazole Ring As One Of The Cyclos Patents (Class 546/273.1)
Bicyclo ring system which is benzimidazole (including hydrogenated) (Class 546/273.4)
  • Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalene
    Publication number: 20020183351
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: April 23, 2002
    Publication date: December 5, 2002
    Applicant: Wyeth
    Inventor: Gary P. Stack
  • Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diaza-cyclopenta[a]naphthalene
    Publication number: 20020183330
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: April 23, 2002
    Publication date: December 5, 2002
    Applicant: American Home Products Corporation
    Inventors: Gary P. Stack, James A. Nelson
  • Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
    Publication number: 20020183354
    Abstract: Compounds of the formula: 1
    Type: Application
    Filed: April 25, 2002
    Publication date: December 5, 2002
    Applicant: Wyeth
    Inventors: Megan Tran, Gary P. Stack
  • Bicyclic imidazo-5-yl-amine derivatives
    Publication number: 20020183320
    Abstract: A novel bicyclic imidazo-5-yl-amine derivative of Formula I, 1
    Type: Application
    Filed: April 8, 2002
    Publication date: December 5, 2002
    Inventors: Matthias Gerlach, Corinna Maul
  • Substituted pyrrolobenzimidazoles for treating inflammatory diseases
    Patent number: 6469174
    Abstract: This invention provides compounds, and pharmaceutically acceptable salts thereof, having the structure shown below, as well as related pharmaceutical compositions, and methods of treatment and synthesis.
    Type: Grant
    Filed: September 25, 2000
    Date of Patent: October 22, 2002
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: John H. Dodd, James R. Henry, Kenneth C. Rupert
  • Hydantoin compounds useful as anti-inflammatory agents
    Publication number: 20020143035
    Abstract: Compounds having the formula (I): 1
    Type: Application
    Filed: November 30, 2001
    Publication date: October 3, 2002
    Inventors: Michele Launay, Dominique Potin, Magali Jeannine Blandine Maillet, Eric Antoine Nicolai, T.G. Murali Dhar, Edwin J. Iwanowicz
  • Small molecule modulators of G protein-coupled receptor six
    Patent number: 6420563
    Abstract: Disclosed herein are small molecule modulators of the G protein coupled receptor six, methods of making such compounds, and methods of using such compounds.
    Type: Grant
    Filed: February 25, 2000
    Date of Patent: July 16, 2002
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Nigel R. A. Beeley, Dominic P. Behan, Derek T. Chalmers, Frederique Menzaghi, Sonja Strah-Pleynet
  • Neuroprotective agents and methods related thereto
    Patent number: 6399606
    Abstract: Neuroprotective agents are disclosed having the following structure: wherein R1, R2, R3, R4 and R5 are as defined herein. Such compounds have utility in the treatment of conditions which benefit from administration of neuroprotective agents generally, including treatment of central and peripheral nervous condition as well as for promoting nerve cell differentiation. Methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more of the compounds of this invention.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: June 4, 2002
    Assignee: Nippon Kayaku Co., Ltd.
    Inventors: Moorthy S. S. Palanki, Shripad S. Bhagwat, Hiroshi Sato, Paul E. Erdman, Mary Doubleday
  • Organometallic complex and organic electroluminescent device using the same
    Patent number: 6383666
    Abstract: Disclosed are new organometallic complex molecules having light-emitting and electron-transporting characteristics. Also disclosed is organic EL (electroluminescent) devices using these organometallic complex molecules as electron-transporting materials. The organometallic complex molecules are used to form a light-emitting layer with or without doping of another light-emitting material. The organometallic complex molecules can also be used in an electron-transporting layer of the organic EL device. The organic EL devices incorporating the organometallic complex molecules have high thermal stability.
    Type: Grant
    Filed: March 31, 2000
    Date of Patent: May 7, 2002
    Assignee: LG Chem, Ltd.
    Inventors: Kongkyeom Kim, Sehwan Son, Okhee Kim, Seok-Hee Yoon, Hyo-Seok Kim, Jaesoon Bae, Youn-Gu Lee
  • Imidazole derivatives and their use as farnesyl protein transferase inhibitors
    Publication number: 20020052376
    Abstract: 1
    Type: Application
    Filed: September 20, 2001
    Publication date: May 2, 2002
    Applicant: AstraZeneca UK Limited
    Inventor: Jean-Claude Arnould
  • Cyclic bis-benzimidazole ligands and metal complexes thereof
    Patent number: 6376664
    Abstract: Cyclic bis benzimidazole ligands of the following formula are formed by contacting a (2-aminophenyl)-benzimidazole-4-carboxaldehyde ethylene acetal or a (2-nitrophenyl)-benzimidazole-4-benzaldehyde with an acid optionally in the presence of a metal or a metal salt. wherein R1 and R2 may be the same or different and are selected from H, an alkyl having 1 to 10 carbon atoms, a benzyl group, a substituted 2-ethylphenyl group, a carbonyl group, a phenyl substituent, a tosyl group, and an alkylsulfonate group; R3 and R4 may be the same or different and are selected from H, methyl, and ethyl; and R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, and R18 may be the same or different and are selected from H, alkyl having 1 to 10 carbon atoms, fluoride, chloride, bromide, iodide, nitro, amino, a carboxylate, an ester, and a phenyl group.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 23, 2002
    Assignee: The Ohio State University
    Inventors: Michael K. Chan, Wai H. Kwok, Huichang Zhang, Maosheng Duan