Patent number: 6444687
Abstract: Compounds of the formula I
or a pharmaceutically acceptable salt, solvate or N-oxide thereof, wherein
X is ═CH— or ═N—;
Y is H, halogen, trihaloalkyl, alkyl, alkenyl, cycloalkyl, cycloalkyl, SH, —S-alkyl, or —CN.
R is alkyl, —CF3, cycloalkyl, heterocycloalkyl, heterocycloalkyl-alkyl, heteroarylalky or adamantyl, or optionally substituted phenyl, phenoxyalkyl, phenylthioalkyl, pyridyl, thienyl, thiazolyl, pyrazinyl, 1,2,5,6-tetrahydropyridine or
wherein R10 and R11 are hydrogen, alkyl or together form a cycloalkyl, are disclosed, as well as pharmaceutical compositions and methods of using said compounds in the treatment of eating disorders and diabetes.
Type:
Grant
Filed:
December 14, 2000
Date of Patent:
September 3, 2002
Assignee:
Schering Corporation
Inventors:
Andrew W. Stamford, Craig D. Boyle, Ying Huang