Chalcogen Bonded Directly To Chalcogen Patents (Class 546/294)
-
Patent number: 4873338Abstract: Compounds corresponding to Formula I ##STR1## wherein R.sup.1 denotes an acyl group andX denotes hydrogen, halogen, alkoxy, aroxy, SO.sub.3 H or a heterocyclic group attached through --O-- or --N<are prepared form a compound corresponding to Formula II ##STR2## wherein X has the meaning already indicated and Q denotes the group required for completing a dicarbonimide ringby reduction of the said compound to the amino compound and acylation into a compound corresponding to Formula III ##STR3## wherein X, Q and R.sup.1 have the meanings indicatedfollowed by conversion of the compound corresponding to Formula III into a compound corresponding to Formula I by hydrazinolytic or hydrolytic decomposition of the dicarbonimide ring.Type: GrantFiled: November 23, 1987Date of Patent: October 10, 1989Assignee: Agfa-Gevaert AktiengesellschaftInventors: Heinz Wiesen, Erich Wolff
-
Patent number: 4863938Abstract: Pyridine derivatives of the formula ##STR1## their tautomers and their salts, in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and n have the meanings given in the claims, can be used as active ingredients in medicaments and are manufactured in a manner known per se.Type: GrantFiled: October 31, 1988Date of Patent: September 5, 1989Assignee: Ciba-Geigy CorporationInventors: Georg von Sprecher, Peter Waldmeier
-
Patent number: 4853389Abstract: This invention relates to substituted 5-pyrimidinesulfonamides, pharmaceutically acceptable salts thereof and to processes for synthesis thereof. Other aspects of the invention concern pharmaceutical compositions containing an instant compound as active ingredient and methods of treatment where there is an indicated need for an antihypertensive and/or diuretic agent.Type: GrantFiled: April 26, 1988Date of Patent: August 1, 1989Assignee: American Home Products CorporationInventors: Terence M. Dolak, Sung J. Lee, James L. Bullington
-
Patent number: 4845108Abstract: Compounds having the formula: ##STR1## are antagonists of leukotrines of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic and anti-inflammatory agents.Type: GrantFiled: February 17, 1987Date of Patent: July 4, 1989Assignee: Merck Frosst Canada, Inc.Inventors: Robert N. Young, Joshua Rokach
-
Patent number: 4826531Abstract: Acrylic acid derivatives having the formula (I): ##STR1## and stereoisomers thereof, wherein W is R.sup.1 O.sub.2 C--C.dbd.CH--ZR.sup.2, R.sup.1 and R.sup.2 are alkyl or fluoroalkyl groups, and Z is oxygen or sulphur; A, B, D and E are hydrogen, halogen, hydroxy or optionally substituted alkyl, alkoxy, aralkyl, arylalkoxy, alkenyl, alkynyl, aryl, aryloxy, arylthio, heteroaryloxy, heteroarylthio, acyloxy, amino, arylazo or acylamino, nitro, cyano, --CO.sub.2 R.sup.3, --CONR.sup.3 R.sup.4, --COR.sup.3, --CR.sup.3 .dbd.NR.sup.4, --N.dbd.CR.sup.3 R.sup.4 or --S(O).sub.n R.sup.3 groups; any two of the groups A, B, D and E, when they are in adjacent positions on the ring, optionally join to form a fused ring, n is 0, 1 or 2; and R.sup.3 and R.sup.4 are hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl or optionally substituted aryl or aralkyl; and metal complexes thereof. These compounds are useful as fungicides, insecticides, nematicides or plant growth regulators.Type: GrantFiled: April 17, 1987Date of Patent: May 2, 1989Assignee: Imperial Chemical Industries PLCInventors: Vivienne M. Anthony, John M. Clough, Paul DeFraine, Christopher R. A. Godfrey, Patrick J. Crowley, Kenneth Anderton
-
Patent number: 4822807Abstract: The present invention provides a process for the preparation of cystalline torasemide in the pure modification I (monoclinic, space group P2.sub.1 /c, melting point 162.degree. C.) from torasemide of modification II (monoclinic, space group P2/n, melting point 169.degree. C.), wherein a suspension of torasemide of modification II is stirred in water with the addition of a catalytic amount of modification I until the rearrangement is complete.The present invention also provides pharmaceutical compositions containing torasemide of modification I.Type: GrantFiled: October 20, 1987Date of Patent: April 18, 1989Assignee: Boehringer Mannheim GmbHInventors: Fritz Topfmeier, Gustav Lettenbauer
-
Patent number: 4808602Abstract: Novel adducts of menadione with pyridine derivatives, said compounds having vitamin B.sub.6 activity and vitamin K activity, and being useful in animal feed premix and animal feed compositions.Type: GrantFiled: February 9, 1987Date of Patent: February 28, 1989Assignee: Heterochemical CorporationInventor: Enrico Bruschi
-
Patent number: 4797491Abstract: Bifunctional chemicals useful for linking aldehyde containing moieties to moieties containing functionalities which are or can be reactive with sulfhydryl are claimed and have the formula:L--S--(CH.sub.2).sub.n1 --CONH--SPACER--NH--Xwherein L is a leaving group selected from --H or --S--Ar, wherein Ar represents optionally substituted phenyl or pyridyl;n.sub.1 =2-4;X is selected from:--CO--Y--CONHNH.sub.2, a hydrazide; ##STR1## a hydrazine; ##STR2## a hydrazine; --CO--Y--NH--CONHNH.sub.2, a semicarbazide; and--CO--Z--NH--CSNHNH.sub.2, a thiosemicarbazide;wherein Y is alkylene or oxaalkylene and Z is alkylene or a polypeptide residue bridging the N-terminal amino group and C-terminal carboxy group thereof;the SPACER is oxaalkylene or oxaalkylene substituted with hydroxyl and specifically includes residues having formulas selected from--(CH.sub.2).sub.n2 --O--(CH.sub.2).sub.n2 --O--(CH.sub.2).sub.n2 --(a)wherein each n2 is independently 2-4 and ##STR3## wherein n3 is 2-6.Type: GrantFiled: March 17, 1986Date of Patent: January 10, 1989Assignee: Cetus CorporationInventors: Danute E. Nitecki, Margaret Moreland
-
Patent number: 4792556Abstract: Psoriasis in mammals is relieved by topically administering naphthalenes of the formula: ##STR1## wherein: R.sup.1 and R.sup.2 are the same and are lower alkoxy or optionally substituted phenoxy,R.sup.3 is lower alkyl, lower alkoxy, or halo and m is 0, 1 or 2 or R.sup.3 is optionally substituted phenyl, optionally substituted phenyl lower alkyl, optionally substituted phenyl lower alkoxy, amino, lower alkylamino, lower dialkylamino, cyano, or S(O).sub.n R wherein R is lower alkyl; optionally substituted phenyl; optionally substituted phenyl lower alkyl; or optionally substituted heterocyclic aryl of three to nine ring atoms containing one or two heteroatoms selected from the group consisting of nitrogen, oxygen and sulfur, and the pharmaceutically acceptable acid addition salts thereof; and m is 1 and n is 0, 1 or 2;at least one of X or Y is C(O)W and the other X or Y is different and is hydrogen, C(O)W or R.sup.Type: GrantFiled: April 28, 1986Date of Patent: December 20, 1988Assignee: Syntex (U.S.A.) Inc.Inventors: D. V. K. Murthy, Michael C. Venuti, John M. Young
-
Patent number: 4791127Abstract: Disclosed herein is a compound of the formula:R.sup.1 --S(O)x--Ar--O--SO.sub.2 --R.sup.2 (I)whereinAr is pyridine ring, pyridazine ring, pyrimidine ring, pyrazine ring, isoquinoline ring or thiazole ring, and those rings may be substituted by 1.about.3 of substituents selected from the group consisting of halogen, C.sub.1 .about.C.sub.4 -alkyl, C.sub.1 .about.C.sub.4 -alkoxy, CF.sub.3 and nitro,R.sup.1 is C.sub.1 .about.C.sub.8 -alkyl; C.sub.1 .about.C.sub.7 -alkyl which is substituted by 1.about.3 of F, Cl or Br, C.sub.1 .about.C.sub.4 -alkoxy or C.sub.1 .about.C.sub.4 -alkylthio; C.sub.3 .about.C.sub.7 -cycloalkyl which may be substituted by 1.about.4 of F, Cl or methyl; C.sub.3 .about.C.sub.6 -cycloalkylmethyl which may be substituted by 1.about.4 of F, Cl, Br or methyl; allyl, propargyl, phenyl or benzyl; R.sup.2 is C.sub.1 .about.C.sub.4 -alkyl which may be substituted by 1.about.3 of F or Cl,x is integer of 0, 1 or 2, excepting wherein Ar is pyridine ring which is substituted by R.sup.Type: GrantFiled: September 30, 1986Date of Patent: December 13, 1988Assignee: Nippon Kayaku Kabushiki KaishaInventors: Shoichi Kato, Shizuo Shimano, Tatsumi Hayaoka, Akio Masui
-
Patent number: 4791123Abstract: There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4 and A have the meanings given in the description, processes for their preparation and insecticidal and acaricidal compositions containing these compounds.Type: GrantFiled: January 22, 1987Date of Patent: December 13, 1988Assignee: Schering Akt.Inventors: Helga Franke, Heinrich Franke, Hans-Rudolf Kruger, Hartmut Joppien, Dietrich Baumert, David Giles
-
Patent number: 4789395Abstract: Disclosed herein are compounds of the general formula ##STR1## which are useful as herbicides.Type: GrantFiled: May 12, 1986Date of Patent: December 6, 1988Assignee: Monsanto CompanyInventors: Len F. Lee, Kerry L. Spear, Mark G. Dolson
-
Patent number: 4766135Abstract: Novel fungicidal pyridyl cyclopropane carboxamides having the general structural formula ##STR1## wherein R is selected from the group consisting of haloalkyl, preferably C.sub.1 -C.sub.3 haloalkyl, C.sub.1 -C.sub.8 alkyl, aryl, substituted aryl, and arylalkyl wherein the preferred aryl is phenyl, the alkyl is C.sub.1 -C.sub.3 alkyl and the preferred substitutions are Cl, Br, F and nitro, alkanoyl, preferably C.sub.1 -C.sub.4 alkanoyl, ##STR2## wherein R.sub.3 and R.sub.4 can be alkyl, alkanoyl, alkoxycarbanoyl, benzyl pyridyl and substituted pyridyl, R.sub.1 is C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 haloalkoxy, preferably methoxy or halomethoxy and halogen wherein the halogen is chlorine, bromine or fluorine, R.sub.2 is hydrogen or methyl, and fungicidally acceptable organic and inorganic salts thereof which are highly effective fungicides for use both as preventive and curative fungicides are disclosed herein. These compounds provide excellent control of fungal growth.Type: GrantFiled: April 15, 1987Date of Patent: August 23, 1988Assignee: Stauffer Chemical Co.Inventors: Don R. Baker, Keith H. Brownell
-
Patent number: 4761480Abstract: Potent dopamine-.beta.-hydroxylase inhibitors having the Formula: ##STR1## which are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.Type: GrantFiled: October 7, 1986Date of Patent: August 2, 1988Assignee: SmithKline Beckman CorporationInventors: Carl Kaiser, Lawrence I. Kruse, Stephen T. Ross
-
Patent number: 4760067Abstract: Organic sulfoxides having a latent allyl group bound to the sulfur are enzyme inhibitors of the suicide or K.sub.cat type.Type: GrantFiled: March 9, 1987Date of Patent: July 26, 1988Assignee: Merck & Co., Inc.Inventor: Raymond A. Firestone
-
Patent number: 4756739Abstract: The compounds of the formula I ##STR1## in which A denotes N or N.fwdarw.O, Z denotes O or NH, R denotes H, (halo)alkyl, (halo)alkenyl, (halo)alkynyl or alkoxycarbonyl, R.sup.1 denotes hydrogen, halogen, amino, --NHOH, hydroxyl, (substituted) phenylazo or a radical of the formulae Y=C=N--, Y.sup.1 Y.sup.2 C.dbd.N--, Y.sup.3 NH-- or ##STR2## K denotes 0 or 1, and m and n, independently of one another, denote a number from 1 to 4, with the proviso that, when Z-R denotes OH or NH.sub.2, (R.sup.1).sub.n denotes at least one radical of the formula ##STR3## or represents two radicals, in the 5 or 6 position of the heterocyclic ring, which, in the 5 position, denote halogen and, in the 6 position, denote a radical of the group comprising halogen, amino, hydroxyl or phenylazo, which may be substituted as specified above, are valuable intermediates in the synthesis of plant protection agents.Type: GrantFiled: December 19, 1986Date of Patent: July 12, 1988Assignee: Hoechst AktiengesellschaftInventors: Andreas Fuss, Volker Koch
-
Patent number: 4743622Abstract: The invention relates to new aromatic alkane derivatives of the general formula ##STR1## in which R.sub.1 is aryl or aryl substituted by C.sub.1-4 alkyl, halo-C.sub.1-4 alkyl, phenyl-C.sub.1-4 alkyl, C.sub.2-4 alkenyl, halo-C.sub.2-4 alkenyl, phenyl-C.sub.2-4 alkenyl, C.sub.2-4 alkynyl, halo-C.sub.2-4 alkynyl, phenyl-C.sub.2-4 alkynyl, C.sub.1-4 alkoxy, halo-C.sub.1-4 alkoxy, phenyl-C.sub.1-4 alkoxy, C.sub.2-4 alkenyloxy, halo-C.sub.2-4 alkenyloxy, phenyl-C.sub.2-4 alkenyloxy, C.sub.2-4 alkynyloxy, halo-C.sub.2-4 alkynyloxy, phenyl-C.sub.2-4 alkynyloxy, alkylsulphonyloxy, haloalkylsulphonyloxy, arylsulphonyloxy, halo, cyano, nitro, aryloxy, haloaryloxy, C.sub.1-4 alkyl-aryloxy, or nitroaryloxy,R.sub.2 is hydrogen or C.sub.1-4 alkyl,R.sub.3 is hydrogen, cyano or ethynyl,R.sub.4 is phenyl or pyridyl or these groups substituted by one or more of C.sub.1-6 alkyl, halo-C.sub.1-6 alkyl, phenyl-C.sub.1-6 alkyl, C.sub.1-6 alkyl interrupted by an O-, N- or S- atom, C.sub.2-4 alkenyl, halo-C.sub.2-4 alkenyl, phenyl-C.Type: GrantFiled: February 11, 1986Date of Patent: May 10, 1988Assignee: Schering AktiengesellschaftInventors: Helga Franke, Heinrich Franke, Hans-Rudolf Kruger, Hartmut Joppien
-
Patent number: 4731108Abstract: Derivatives of 4-((aryloxy)phenoxy)alkenols, their preparation and use as active herbicides for the postemergent control of grassy weeds and especially the control of said weeds in the presence of corn plants are disclosed.Type: GrantFiled: March 7, 1986Date of Patent: March 15, 1988Assignee: The Dow Chemical CompanyInventors: James A. Turner, Wendy S. Jacks, Paul S. Zorner
-
Patent number: 4730050Abstract: A derivative of a fibrinolytic enzyme in which the catalytic site on the enzyme which is responsible for fibrinolytic activity is blocked by a human protein attached thereto by way of a reversible linking group.Type: GrantFiled: April 3, 1987Date of Patent: March 8, 1988Assignee: Beecham Group p.l.c.Inventor: Richard A. G. Smith
-
Patent number: 4678509Abstract: Certain novel pyridinyloxyphenoxy alkanoic acids, pyridinylthiophenoxy alkanoic acids, derivatives thereof and related compounds are described. More specifically, these novel compounds bear a fluorine substituent in the 3-position of the pyridinyl group and in the 5-position the substituent is selected from chlorine, CF.sub.3, CF.sub.2 Cl or CF.sub.2 H. These novel compounds exhibit surprising preemergent and postemergent activity in the control of grassy weeds.Type: GrantFiled: November 1, 1985Date of Patent: July 7, 1987Assignee: The Dow Chemical CompanyInventors: Howard Johnston, Lillian H. Troxell
-
Patent number: 4670470Abstract: Organic sulfoxides having a latent allyl group bound to the sulfur are enzyme inhibitors of the suicide or K.sub.cat type.Type: GrantFiled: August 29, 1985Date of Patent: June 2, 1987Assignee: Merck & Co., Inc.Inventor: Raymond A. Firestone
-
Patent number: 4668800Abstract: There is described a process for producing sulfonylureas of the formula ##STR1## wherein G is an unsubstituted or substituted furanyl, thienyl, pyrrolyl, pyridinyl or phenyl radical,X is alkyl, haloalkyl, alkoxy, alkylthio, halogen, haloalkoxy, alkylamino or dialkylamino,Y is alkyl, alkoxy or haloalkoxy,Z is a nitrogen atom or the methyne group --CH.dbd..This novel process comprises reacting a sulfonamide of the formulaG--SO.sub.2 --NH.sub.2,in the presence of a base, with a chloroformic acid ester of the formulaCl--CO--Q--T,or a sulfonyl chloride of the formulaG--SO.sub.2 Cl,in the presence of a base, with a urethane of the formulaH.sub.2 N--CO--Q--T;and converting the formed carbamate of the formulaG--SO.sub.2 --NH--CO--Q--Tby reaction with an amine of the formula ##STR2## into the sulfonylurea of the above formula. There are also described novel sulfonylcarbamates of the above formula as intermediates.Type: GrantFiled: March 4, 1985Date of Patent: May 26, 1987Assignee: Ciba-Geigy CorporationInventors: Willy Meyer, Werner F/o/ ry, Werner T/o/ pfl
-
Patent number: 4666928Abstract: Compounds having the formula: ##STR1## are antagonists of leukotrines of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic and anti-inflammatory agents.Type: GrantFiled: August 30, 1984Date of Patent: May 19, 1987Assignee: Merck Frosst Canada, Ind.Inventors: Robert N. Young, Joshua Rokach
-
Patent number: 4664848Abstract: Detergent compositions which comprise from about 0.05 to about 95% by weight of a water-soluble cationic compound having clay soil removal/anti-redeposition properties. These compounds are selected from ethoxylated cationic monoamines, ethoxylated cationic diamines, ethoxylated cationic polyamines, ethoxylated cationic polymers, and mixtures thereof. In addition to the cationic compounds, the detergent compositions further comprise from about 1 to about 75% by weight of a nonionic, anionic, ampholytic, zwitterionic, or cationic detergent surfactant or mixture thereof. In addition to these detergent surfactants, the detergent composition can optionally comprise from 0 to about 80% by weight of a detergent builder.Type: GrantFiled: November 22, 1983Date of Patent: May 12, 1987Assignee: The Procter & Gamble CompanyInventors: Young S. Oh, Eugene P. Gosselink
-
Patent number: 4652574Abstract: A compound of the formula: ##STR1## wherein R.sup.1 is C.sub.1 -C.sub.12 alkyl, R.sup.2 is C.sub.1 -C.sub.12 alkyl or C.sub.1 -C.sub.4 alkyl which is substituted with halogen, X is halogen, m is 0, 1 or 2 and n is 0, 1 or 2,a process for producing said compound and use thereof as an insecticide acaricide and nematicide.Type: GrantFiled: November 12, 1985Date of Patent: March 24, 1987Assignee: Nippon Kayaku Kabushiki KaishaInventors: Shoichi Kato, Shizuo Shimano, Tatsumi Hayaoka, Akio Masui
-
Patent number: 4647569Abstract: Pyridylaminoethene derivatives of the formula: ##STR1## wherein R.sup.1 is pyridyl, unsubstituted or substituted by one or more substituents R.sup.4 selected from halogen, amino, carboxy, cyano nitro, hydroxy, formyl, trifluoromethyl, aryl, aryloxy, arylthio, benzyloxycarbonylamino, sulphamoyl, tetrazol-5-yl, carbamoyl, thiocarbamoyl, arylcarbamoyl, aroyl, alkyl, alkoxy, alkylthio, alkylsulphonyl, alkylamino, alkylsulphamoyl, arylalkyl, alkanoyl, alkoxycarbonyl, alkoxycarbonylamino, alkylcarbamoyl, alkanoylamino, N-benzyloxycarbonyl-N-alkylamino, or dialkylsulphamoyl, dialkylamino or dialkylcarbamoyl, wherein the alkyl groups may together form a ring, and R.sup.2 and R.sup.3 each represents phenyl, unsubstituted or substituted by one or more substituents R.sup.4 as hereinbefore defined, possess antiarthritic properties.Type: GrantFiled: September 19, 1985Date of Patent: March 3, 1987Assignee: May & Baker LimitedInventors: Raymond F. Collins, Philip Knowles, Libert C. Saunders, Francis J. Tierney, Peter J. Warne
-
Patent number: 4647655Abstract: There is described a method for splitting at least one disulphide bond --S--S--, where each of the sulphur atoms is directly bound covalently to its respective aliphatic carbon atom in an organic substance which contains at least one such disulphide bond, in which each bond --S--S-- which is split is converted substantially to two reactive groups of the formulae --S--S--R.sub.1 and R.sub.2 --S--S--, where R.sub.1 and R.sub.2 are equal or different and each is an organic residue. Splitting of the bond is effected by reacting said organic substance with a mixture of a compound R.sub.3 --S--S--R.sub.4 and a compound capable of existing in the tautomeric forms R.sub.5 --S--H and HR.sub.5 .dbd.S or corresponding resonance-stabilized anion forms, in which compounds the residues R.sub.3, R.sub.4 and R.sub.5 (i) are organic residues of which all are different, two are equal or all are equal, and (ii) are defined in (a) that each of the aforesaid sulphur atoms in the compounds R.sub.3 --S--S--R.sub. 4 and R.sub.Type: GrantFiled: January 16, 1985Date of Patent: March 3, 1987Assignee: Pharmacia AktiebolagInventors: Rolf E. Axen, Jan P. Carlsson, Hakan N. Drevin
-
Patent number: 4647665Abstract: A process for the preparation of a sulphonyliso(thio)urea of the formula ##STR1## in which R.sup.1 represents an optionally substituted radical from the group consisting of alkyl, aralkyl, aryl and heteroaryl,R.sup.2 represents an optionally substituted and/or optionally fused, six-membered aromatic heterocycle containing at least one nitrogen atom,R.sup.3 represents an optionally substituted radical from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkyl-alkyl and aralkyl, andQ represents oxygen or sulphur,comprising reacting a sulphonylguanidine of the formula ##STR2## in which R.sup.4 represents an optionally substituted hydrocarbon radical,with a compound of the formulaH--Q--R.sup.3at a temperature between 0.degree. C. and 150.degree. C. The products are known herbicides.Type: GrantFiled: August 23, 1985Date of Patent: March 3, 1987Assignee: Bayer AktiengesellschaftInventors: Hans-Joachim Diehr, Christa Fest, Rolf Kirsten, Joachim Kluth, Klaus-Helmut Muller, Theodor Pfister, Uwe Priesnitz, Hans-Jochem Riebel, Wolfgang Roy
-
Patent number: 4634711Abstract: Potent dopamine-.beta.-hydroxylase inhibitors having the formula: ##STR1## which are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors, and methods of using these inhibitors to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.Type: GrantFiled: August 2, 1985Date of Patent: January 6, 1987Assignee: Smithkline Beckman CorporationInventors: Carl Kaiser, Lawrence I. Kruse, Stephen T. Ross
-
Patent number: 4631081Abstract: The invention concerns novel compounds of the formula I ##STR1## wherein: Z is selected from oxygen and the group --YAn wherein Y is selected from C.sub.1 to C.sub.6 alkyl and benzyl and An is an anion;k is zero or the integer 1;n is an integer selected from 3 and 4;X is selected from halogen, nitro, cyano, alkyl, substituted alkyl, hydroxy, alkoxy, substituted alkoxy, alkenyl, alkenyloxy, alkynyl, alkynyloxy, acyloxy, alkoxycarbonyl, alkylthio, alkylsulfinyl, alkylsulfonyl, sulfamoyl, substituted sulfamoyl, alkanoyloxy, benzyloxy, substituted benzyloxy, amino, substituted amino and the groups formyl and alkanoyl and the oxime, imine and Schiff base derivatives thereof;R.sup.1 is selected from hydrogen, alkyl, alkenyl, alkynyl, substituted alkyl, alkylsulfonyl, arylsulfonyl, acyl and an inorganic or organic cation;R.sup.2 is selected from alkyl, substituted alkyl, alkenyl, haloalkenyl, alkynyl and haloalkynyl;R.sup.3 is selected from alkyl, fluoroalkyl, alkenyl, alkynyl, and phenyl; andR.sup.Type: GrantFiled: September 27, 1983Date of Patent: December 23, 1986Assignee: ICI Australia LimitedInventors: Keith G. Watson, Graham J. Bird, Graeme J. Farquharson, Richard J. Conway, Peter G. Tucker
-
Patent number: 4629802Abstract: A novel process for producing sulfonylureas of the formula I having a herbicidal action and an action regulating plant growth ##STR1## wherein A is an unsubstituted or substituted phenyl, naphthyl, furan, thiophene or pyridine group, E is a nitrogen atom or the methine group, R.sub.a is hydrogen, halogen, C.sub.1 -C.sub.5 -alkyl, C.sub.1 -C.sub.5 -haloalkyl, C.sub.1 -C.sub.5 -alkoxy, C.sub.1 -C.sub.5 -haloalkoxy, C.sub.1 -C.sub.5 -alkylthio or C.sub.2 -C.sub.10 -alkoxyalkoxy, and R.sub.b is the same as R.sub.Type: GrantFiled: March 1, 1985Date of Patent: December 16, 1986Assignee: Ciba-Geigy CorporationInventors: Haukur Kristinsson, Werner Topfl
-
Patent number: 4629497Abstract: The subject matter of this invention are the following sulfonamides: ##STR1## wherein X is chlorine or trifluoromethylY is chlorine or hydrogenZ is hydrogen or methylType: GrantFiled: August 19, 1985Date of Patent: December 16, 1986Assignee: Sandoz Ltd.Inventors: Louis G. Nickell, Leonard J. Stach, Takeo Hokama
-
Patent number: 4623381Abstract: Cyclohexane-1,3-dione derivatives of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3, A and X have the meanings given in the description, and their use for controlling undesirable plant growth.Type: GrantFiled: August 10, 1983Date of Patent: November 18, 1986Assignee: BASF AktiengesellschaftInventors: Dieter Jahn, Rainer Becker, Norbert Goetz, Michael Keil, Bruno Wuerzer
-
Patent number: 4616087Abstract: A process for preparing substituted-pyridines having a sulfonyl type substituted at the 3 or 5 position of the pyridine ring and a phenoxy type substituent at the 2 position is described.Type: GrantFiled: May 21, 1982Date of Patent: October 7, 1986Assignee: The Dow Chemical CompanyInventor: Steven G. Wood
-
Patent number: 4609395Abstract: Benzylsulfonylureas and arylsulfamoylureas are useful as pre-emergent and post-emergent herbicides and as plant growth regulants.Type: GrantFiled: December 26, 1984Date of Patent: September 2, 1986Assignee: E. I. Du Pont de Nemours and CompanyInventors: Robert J. Pasteris, Mark E. Thompson
-
Patent number: 4603208Abstract: Novel polyprenyl compounds have the general formula: ##STR1## represents a cis-isoprene unit, n is an integer of 11-19, Z.sup.1 is --CH.sub.2 OH or a functional precursor thereof, and either one of R.sup.1 and R.sup.2 is a hydrogen atom and the other is --S(O).sub.m R.sup.3 in which m is an integer of 0 (zero), 1 or 2 and R.sup.3 is a phenyl, naphthyl, pyridyl or thiazolinyl group or such group substituted with at least one lower alkyl and/or halogen substituent. The topic novel polyprenyl compounds can be synthesized from derivatives of the polyprenol which is obtainable from leaves of Ginkgo biloba or Cedrus deodara, among others, by extraction, if necessary followed by hydrolytic treatment. The novel polyprenyl compounds can be converted to mammalian dolichols or precursors thereof by reductive elimination of the --S(O).sub.m R.sup.3 group.Type: GrantFiled: February 10, 1983Date of Patent: July 29, 1986Assignee: Kuraray Co., Ltd.Inventors: Takashi Onishi, Shigeaki Suzuki, Fumio Mori, Tetsuo Takigawa, Yoshiji Fujita, Masao Mizuno, Takashi Nishida
-
Patent number: 4602938Abstract: Guanidine derivatives of the formula ##STR1## in which R.sup.2 represents a six-membered aromatic heterocyclic structure which contains at least one nitrogen atom and is substituted by halogen, amino, cyano or formyl and/or by optionally substituted radicals from the series comprising alkyl, alkoxy, alkylamino, dialkylamino, alkylcarbonyl and alkoxycarbonyl, and/or is optionally fused,R.sup.3 represents hydrogen, an optionally substituted radical from the series comprising alkyl, cycloalkyl, alkenyl, alkinyl and aralkyl, or the radical --S(O).sub.n --R.sup.6,the other radicals can have varied meanings, andacid adducts and salts thereof,which possess herbicidal and plant growth regulating activity.Type: GrantFiled: February 9, 1984Date of Patent: July 29, 1986Assignee: Bayer AktiengesellschaftInventors: Koichi Moriya, Theodor Pfister, Hans-Jochem Riebel, Ludwig Eue, Robert R. Schmidt, Klaus Lurssen
-
Patent number: 4599105Abstract: Novel compounds, e.g., N-methanesulfonyl 2-((5-(3-fluoro-5-(trifluoromethyl)-2-pyridinyl)oxy)-2-nitro-5-phenoxy)pro pionamide are selective herbicides useful for controlling weeds in valuable crops.Type: GrantFiled: June 20, 1983Date of Patent: July 8, 1986Assignee: The Dow Chemical CompanyInventors: Sudarshan K. Malhotra, B. Clifford Gerwick, III
-
Patent number: 4586953Abstract: Herbicidal pyridine compounds of the formula (I): ##STR1## wherein Z may be halogen, or a fluorine- or chlorine-substituted alkyl group of 1 to 4 carbon atoms, and Y may be hydrogen, halogen, or a fluorine- or chlorine-substituted alkyl group of 1 to 4 carbon atoms; X may be an OH group or an acyloxy group; a halogen atom; an amino group, a mono- or di-alkyl amino group, or an alkanoylamido group; an alkoxy group optionally substituted by hydroxy or alkoxy; or a mercapto group, an alkylthio group, or a phenylthio group. The invention also provides herbicidal compositions containing the compounds, and processes for making the compounds.Type: GrantFiled: January 31, 1984Date of Patent: May 6, 1986Assignee: Imperial Chemical Industries PLCInventor: David Cartwright
-
Patent number: 4565568Abstract: Certain novel pyridinyloxyphenoxy alkanoic acids, pyridinylthiophenoxy alkanoic acids, derivatives thereof and related compounds are described. More specifically, these novel compounds bear a fluorine substituent in the 3-position of the pyridinyl group and in the 5-position the substituent is selected from chlorine, CF.sub.3, CF.sub.2 Cl or CF.sub.2 H. These novel compounds exhibit surprising preemergent and postemergent activity in the control of grassy weeds.Type: GrantFiled: May 23, 1983Date of Patent: January 21, 1986Assignee: The Dow Chemical CompanyInventors: Howard Johnston, Lillian H. Troxell
-
Patent number: 4563470Abstract: A salt of formula I or formula II ##STR1## wherein n is 2 or 3 and M is an alkali metal or alkaline earth metal. Such compounds can be used to introduce the metal, e.g. magnesium, ion into cells to cure a deficiency thereof.Type: GrantFiled: July 1, 1983Date of Patent: January 7, 1986Assignee: Les Laboratories MeramInventor: Jean P. Durlach
-
Patent number: 4558071Abstract: Organic sulfoxides having a latent allyl group bound to the sulfur are enzyme inhibitors of the suicide or K.sub.cat type.Type: GrantFiled: February 25, 1983Date of Patent: December 10, 1985Assignee: Merck & Co., Inc.Inventor: Raymond A. Firestone
-
Patent number: 4540578Abstract: Novel phenoxyphenyl and phenoxypyridyl benzoyl ureas and a process for their preparation are provided. The novel ureas are useful as the active toxicant in pesticidal compositions.Type: GrantFiled: December 30, 1982Date of Patent: September 10, 1985Assignee: Union Carbide CorporationInventors: David T. Chou, John A. Durden, Themistocles D. J. D'Silva
-
Patent number: 4508561Abstract: 1-Phenylethyl sulfone derivatives substituted by a halogenated alkyloxy group is represented by the general formula ##STR1## where R is an alkyl group substituted by a halogen atom, n is 1 or 2, each of P and Q is a hydrogen atom or a lower alkyl group and each of X and Y is a hydrogen atom, a lower alkyl group or a halogen atom. The compounds are effective as a herbicide. Also disclosed is a process for their preparation.Type: GrantFiled: January 12, 1983Date of Patent: April 2, 1985Assignee: Nissan Chemical Industries Ltd.Inventors: Gozyo Sakata, Tatsuo Numata, Kenzi Makino, Takuya Kakuta, Kazuya Kusano, Takasi Ikai, Tosihiko Oguti
-
Patent number: 4508562Abstract: Benzylsulfinyl pyridine-N-oxides represented by the formula: ##STR1## wherein X is a chlorine atom or a bromine atom; and Y and Z, which may be the same or different, are each a chlorine atom or a fluorine atom, is disclosed. A process for producing the same, and a herbicide containing the same as an active ingredient are also disclosed.Type: GrantFiled: May 27, 1983Date of Patent: April 2, 1985Assignee: Sumitomo Chemical Company, LimitedInventors: Koji Nakayama, Ryo Yoshida, Hiroshi Matsumoto
-
Patent number: 4505917Abstract: Selected (1-oxo-2-pyridyl) disulfides are used as active ingredients in animal feed compositions and in methods for increasing the growth and feed efficiency of monogastric animals. A useful new compound of this invention is 2-carboxyphenyl (1-oxo-2-pyridyl) disulfide.Type: GrantFiled: September 21, 1982Date of Patent: March 19, 1985Assignee: SmithKline Beckman CorporationInventors: Govind K. Menon, Winfred J. Sanders
-
Patent number: 4503230Abstract: A process for making a compound of the formula ##STR1## is disclosed wherein: R is C.sub.1 -C.sub.12 alkyl, allyl or benzyl,R.sup.1 and R.sup.2 are hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, or phenyl,R.sup.3 is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, CF.sub.3, NO.sub.2, phenyl or phenoxy, m is an integer from 1 to 3 andn is zero or 1,by contacting a compound of said formula where R is hydrogen with certain halohydrocarbons in the presence of solid KOH, a phase transfer catalyst, a solvent and an effective amount of water. The process of this invention permits production of the above compound, useful as a herbicide, without the need for cocatalysts or excess high concentration of NaOH and water.Type: GrantFiled: August 20, 1981Date of Patent: March 5, 1985Assignee: Uniroyal, Inc.Inventors: John A. Minatelli, Shih-Yu Ma
-
Patent number: 4501673Abstract: Betaines containing the pyridine nucleus, some of which are novel per se, are dissolved in sea water or formation water, the concentration of betaine being from 200 to 100,000 ppm, to give a surfactant solution suitable for displacing crude oil from a formation in an enhanced oil recovery process. These betaines have low interfacial tension (against oil), a high tolerance towards divalent metal ions and good temperature stability as compared with betaines previously proposed for enhanced oil recovery.Type: GrantFiled: March 31, 1982Date of Patent: February 26, 1985Assignee: The British Petroleum Company p.l.c.Inventor: Phillip K. G. Hodgson
-
Patent number: 4490532Abstract: Hydrogen chloride is passed into p-xylene and acetaldehyde to form bis-1-chloroethyl ether; the latter is converted to 2-(1-chloroethyl)-1,4-dimethylbenzene by the action of sulfuric acid and hydrogen chloride. Alkali metal hydrogen sulfide in aqueous methanol or ethanol converts the 2-(1-chloroethyl)-1,4-dimethylbenzene to alpha,2,5-trimethylbenzenemethanethiol; the sodium salt of the latter reacted with 2-chloropyridine-1-oxide yields 2-[1-(2,5-dimethylphenyl)ethylthio]pyridine-1-oxide which is then oxidized with hydrogen peroxide and alkali metal tungstate or tungstic acid to form 2-[1-(2,5-dimethylphenyl)ethylsulfonyl]pyridine-1-oxide.Type: GrantFiled: July 28, 1980Date of Patent: December 25, 1984Assignee: Uniroyal Ltd.Inventor: John W. Harris
-
Patent number: 4477672Abstract: 3-Alkylsulfonyloxy-4-substituted phenoxy alkanoic acid esters and the use thereof as intermediates for and as herbicides.Type: GrantFiled: August 6, 1982Date of Patent: October 16, 1984Assignee: Zoecon CorporationInventors: Gustave K. Kohn, Joe T. Bamberg