The Metal Is Bonded Directly To Chalcogen Which Chalcogen Is Attached Directly Or Indirectly To The Six-membered Hetero Ring By Nonionic Bonding Patents (Class 546/6)
  • Patent number: 9382273
    Abstract: Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: July 5, 2016
    Assignee: ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Jian Li, Eric Turner
  • Patent number: 9306178
    Abstract: The current invention relates to novel platinum(II) based organometallic materials. These materials show high emission quantum efficiencies and low self-quenching constant. Also provided are high efficiency, green to orange emitting organic light-emitting diode (OLED) that are fabricated using platinum(II) based organometallic materials as the light-emitting material. The organometallic materials of the invention are soluble in common solvents; therefore, solution process methods such as spin coating and printing can be used for device fabrication. The devices fabricated from these materials show low efficiency roll-off.
    Type: Grant
    Filed: April 11, 2013
    Date of Patent: April 5, 2016
    Assignees: THE UNIVERSITY OF HONG KONG, VERSITECH LIMITED
    Inventors: Chi Ming Che, Chi Fai Kui, Chi Chung Kwok
  • Publication number: 20150112066
    Abstract: The present invention relates to asymmetric catalysts, including redox-reconfigurable asymmetric catalysts. Methods of producing compounds having one or more stereocenters using the asymmetric catalysts of the present invention are also disclosed.
    Type: Application
    Filed: June 11, 2013
    Publication date: April 23, 2015
    Applicant: NEW YORK UNIVERSITY
    Inventors: James Canary, Shahab Mortezaei
  • Patent number: 8980876
    Abstract: The present invention is directed to a method of inhibiting aconitase activity of fungal cells in an individual, the method comprising administering an inhibitor of aconitase activity to the fungal cell in an amount effective to inhibit activity of aconitase by said fungal cells.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: March 17, 2015
    Assignee: The Procter & Gamble Company
    Inventors: James Robert Schwartz, Charles Winston Saunders, Robert Scott Youngquist, Jun Xu
  • Publication number: 20150056115
    Abstract: Provided is a compound including an activated metal and a ligand, a carbon dioxide (CO2) absorbent including the compound, a method of preparing the CO2 absorbent, and a method of removing CO2.
    Type: Application
    Filed: June 2, 2014
    Publication date: February 26, 2015
    Applicant: KOREA INSTITUTE OF ENERGY RESEARCH
    Inventors: Soon Kwan Jeong, Yeo Il Yoon, Sung Chan Nam, Soo Hyun Chol, Sung Ho Yoon, Dong Kook Park
  • Publication number: 20150011765
    Abstract: A copper(I) complex is represented by the following Formula (1): [Cua(XS)b(L)c], wherein, L is triphenylphosphine, acetonitrile, tri-iso-butylphosphine, or a substituted or unsubstituted heterocyclic compound having 5 to 18 carbon atoms, a is an integer from 2 to 6, b is an integer from 2 to 6, c is an integer from 0 to 6, X is a substituted or unsubstituted aryl group, substituted or unsubstituted carbazole, or PR3, where R is a substituted or unsubstituted phenyl group or a substituted or unsubstituted cyclohexyl group.
    Type: Application
    Filed: July 3, 2014
    Publication date: January 8, 2015
    Applicant: HOKKAIDO UNIVERSITY
    Inventors: Nobutaka AKASHI, Masako KATO, Atsushi KOBAYASHI, Koutarou SHIMADA, Yuki OHARA
  • Publication number: 20140336354
    Abstract: The present invention describes metal salen complexes having dianionic counterions. Such complexes can be readily precipitated and provide an economical method for the purification and isolation of the complexes, and are useful to prepare novel polymer compositions.
    Type: Application
    Filed: December 11, 2012
    Publication date: November 13, 2014
    Inventors: Gabriel E. Job, Jay J. Farmer, Anna E. Cherian
  • Patent number: 8877353
    Abstract: Described are novel platinum (II) containing organometallic materials. These materials show green to orange emissions with high emission quantum efficiencies. Using the materials as emitting materials; pure green emitting organic light-emitting diodes can be fabricated. Since the novel platinum (II) containing organometallic materials are soluble in common solvents, solution process methods such as spin coating and printing can be used for device fabrication.
    Type: Grant
    Filed: July 13, 2011
    Date of Patent: November 4, 2014
    Assignee: Versitech Limited
    Inventors: Chi Ming Che, Chi Fai Kui, Chi Chung Kwok
  • Publication number: 20140296061
    Abstract: A novel transition metal trimer compound/catalyst is disclosed. A method of increasing the overall mass transfer rate of acid gas scrubbing solvents utilizing that catalyst is also provided.
    Type: Application
    Filed: March 29, 2013
    Publication date: October 2, 2014
    Applicant: The University of Kentucky Research Foundation
    Inventor: The University of Kentucky Research Foundation
  • Publication number: 20140248342
    Abstract: The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use in the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias.
    Type: Application
    Filed: May 30, 2012
    Publication date: September 4, 2014
    Applicant: Vifor (International) AG
    Inventors: Thomas Bark, Wilm Buhr, Susanna Burckhardt, Michael Burgert, Camillo Canclini, Franz Dürrenberger, Felix Funk, Peter Geisser, Aris Kalogerakis, Simona Mayer, Erik Philipp, Stefan Reim, Diana Sieber, Jörg Schmitt, Katrin Schwarz, Jürgen Klotz
  • Publication number: 20140212335
    Abstract: Nanoparticles as described herein are configured to bind to bacterial contaminants, such as Gram positive bacteria, Gram negative bacteria, and endotoxins. The nanoparticles include a core comprising a magnetic material; and a plurality of ligands attached to the core. The ligands include, for example, bis(dipicolylamine) (“DPA”) coordinated with a metal ion, e.g., Zn2+ or Cu2+, to form, e.g., bis-Zn-DPA or bis-Cu-DPA, which can bind to the bacterial contaminants. The nanoparticles can be included in compositions for use in methods and systems to separate bacterial contaminants from liquids, such as liquids, such as blood, e.g., whole or diluted blood, buffer solutions, albumin solutions, beverages for human and/or animal consumption, e.g., drinking water, liquid medications for humans and/or animals, or other liquids.
    Type: Application
    Filed: January 29, 2014
    Publication date: July 31, 2014
    Applicants: Massachusetts Institute of Technology, Children's Medical Center Corporation
    Inventors: Jung-Jae Lee, Kyung Jae Jeong, Daniel S. Kohane
  • Publication number: 20140148425
    Abstract: Photosensitive compounds for use in a method of treating a disease or condition are described. The photosensitive compounds have the formula R—Y, wherein R is a ruthenium complex and Y is at least one sulphur-containing photoreleasable group, and the compounds comprise at least one ruthenium-sulphur bond; or a pharmaceutically acceptable salt, solvate, ester or amide, such that upon influence of visible or near infra-red light (400-1400 nm) in vivo, said at least one ruthenium-sulphur bond is broken, thereby generating a pharmacologically active compound.
    Type: Application
    Filed: October 18, 2011
    Publication date: May 29, 2014
    Inventor: Sylvestre Bonnet
  • Publication number: 20140106960
    Abstract: The invention relates to C—H activated olefin metathesis catalyst compounds, the preparation of such compounds, and the use of such catalysts in the metathesis of olefins and olefin compounds, more particularly, the use of such catalysts in Z selective olefin metathesis reactions. In general, the catalyst compounds of the invention comprise a Group 8 metal (M), an alkylidene moiety (?CR1R2), or more generally (?(C)mCR1R2), an anionic ligand (X1), two or three neutral ligands (L1, L2, and L3) and a 2-electron anionic donor bridging moiety (Q*) that forms a chelate ring structure in conjunction with L1 and M.
    Type: Application
    Filed: January 17, 2012
    Publication date: April 17, 2014
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Koji Endo, Benjamin Keith Keitz, Myles Benton Herbert, Paresma Rasiklal Patel, Robert Howard Grubbs
  • Publication number: 20140088066
    Abstract: The present disclosure relates to novel pharmaceutical compositions comprising a nanoparticle associated with, tether to, or encapsulating a platinum-based active pharmaceutical agent. The platinum-based drug is released from the nanoparticles in a controlled fashion. Also contemplated are methods of making the nanoparticles, as well as methods for using them in the treatment or prevention of diseases or conditions. One embodiment relates to phenanthriplatin nanoparticles and methods of using and making the same.
    Type: Application
    Filed: September 11, 2013
    Publication date: March 27, 2014
    Applicant: Blend Therapeutics
    Inventors: Mark T. Bilodeau, Craig A. Dunbar, Timothy E. Barder, Edward R. Lee, Rossitza G. Alargova, Danielle N. Rockwood, Benoît Moreau, Rajesh Shinde, Melaney Bouthillette
  • Publication number: 20140088308
    Abstract: Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials, dental bonding agents or other dental materials, to produce materials with high fluoride release rates, and high fluoride recharge capability. Such dental restorative materials may help reduce the level of dental caries in patients, particularly the level of caries occurring on the margins of the restorative materials.
    Type: Application
    Filed: November 12, 2013
    Publication date: March 27, 2014
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Xiaoming Xu, Shailaja Jayaramachandran
  • Publication number: 20140066290
    Abstract: The present invention provides a cathode catalyst for an air secondary cell having both excellent oxygen reduction activity and excellent water oxidation activity, and an air secondary cell that uses the catalyst. The present invention relates to a cathode catalyst for an air secondary cell in which the catalyst contains a polynuclear metal complex.
    Type: Application
    Filed: April 27, 2012
    Publication date: March 6, 2014
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventors: Nobuyoshi Koshino, Hideyuki Higashimura
  • Publication number: 20140051859
    Abstract: The present invention relates to a novel nickel complex and its derivatives, which mimic the active site of Ni-containing superoxide dismutase (NiSOD). The five-coordinate Ni(II) and Ni(III) complexes or their derivatives, and six-coordinate derivatives have the following structures of formula (I) and (II): The nickel complexes and their derivatives of the invention act as anti-oxidants or free radical scavengers. The invented nickel complexes can be used in the preparation of medicines, health foods or cosmetics for human, animals and plants, or can be used in environmental or soil protection.
    Type: Application
    Filed: October 30, 2013
    Publication date: February 20, 2014
    Applicant: National Taiwan Normal University
    Inventors: Way-Zen LEE, Chien-Wei CHIANG, Tsung-Han LIN, Ting-Shen KUO
  • Publication number: 20140039169
    Abstract: The present invention provides luminescent complexes between a lanthanide ion and an organic ligand which contains 1,2-hydroxypyridinone units. The complexes of the invention are stable in aqueous solutions and are useful as molecular probes, for example in medical diagnostics and bioanalytical assay systems. The invention also provides methods of using the complexes of the invention.
    Type: Application
    Filed: October 8, 2013
    Publication date: February 6, 2014
    Inventors: Kenneth N. RAYMOND, Jide Xu, Evan G. Moore, Eric J. Werner
  • Patent number: 8642763
    Abstract: The present invention relates to a novel nickel complex and its derivatives, which mimic the active site of Ni-containing superoxide dismutase (NiSOD). The five-coordinate Ni(II) and Ni(III) complexes or their derivatives, and six-coordinate derivatives have the following structures of formula (I) and (II): The nickel complexes and their derivatives of the invention act as anti-oxidants or free radical scavengers. The invented nickel complexes can be used in the preparation of medicines, health foods or cosmetics for human, animals and plants, or can be used in environmental or soil protection.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: February 4, 2014
    Assignee: National Taiwan Normal University
    Inventors: Way-Zen Lee, Chien-Wei Chiang, Tsung-Han Lin, Ting-Shen Kuo
  • Publication number: 20140024833
    Abstract: The invention relates to a process for preparing primary amines by alcohol amination of alcohols with ammonia with the elimination of water, where the alcohol amination is carried out under homogeneous catalysis in the presence of at least one complex catalyst which comprises ruthenium and at least one at least bidental donor ligand, but no anionic ligands.
    Type: Application
    Filed: July 23, 2013
    Publication date: January 23, 2014
    Applicant: BASF SE
    Inventors: Mathias SCHELWIES, Marion Brinks, Thomas Schaub, Johann-Peter Melder, Rocco Paciello, Martin Merger
  • Publication number: 20140011219
    Abstract: Novel grafted dinuclear metal complexes having formula (I) or of formula (II) wherein M represents a metal ion, and also the use thereof as sensors in a method for detecting and/or characterising cellular microparticles.
    Type: Application
    Filed: March 23, 2012
    Publication date: January 9, 2014
    Applicant: Centre National De La Recherche Scientifique (CNRS)
    Inventors: Catherine Belle, Gisele Gellon, Laurent Plawinski, Loic Doeuvre, Eduardo Angles cano
  • Patent number: 8609843
    Abstract: Disclosed are nitric oxide delivery agents and methods of their use, more specifically to photoactive compounds, which are able to perform targeted delivery of nitric oxide in vitro and in vivo and are useful for medicinal applications including, but not limited, to blood pressure regulation and cancer treatment.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: December 17, 2013
    Assignee: The Regents of the University of California
    Inventor: Pradip K. Mascharak
  • Publication number: 20130317224
    Abstract: The present invention relates to a novel nickel complex and its derivatives, which mimic the active site of Ni-containing superoxide dismutase (NiSOD). The five-coordinate Ni(II) and Ni(III) complexes or their derivatives, and six-coordinate derivatives have the following structures of formula (I) and (II): The nickel complexes and their derivatives of the invention act as anti-oxidants or free radical scavengers. The invented nickel complexes can be used in the preparation of medicines, health foods or cosmetics for human, animals and plants, or can be used in environmental or soil protection.
    Type: Application
    Filed: June 8, 2012
    Publication date: November 28, 2013
    Inventors: Way-Zen Lee, Chien-Wei Chiang, Tsung-Han Lin, Ting-Shen Kuo
  • Patent number: 8586201
    Abstract: An iridium complex is disclosed, which has a structure represented by the following formula (I): wherein each of Z1 and Z3 represents an atomic group for forming a nitrogen-containing heteroaryl group or a nitrogen-containing heterocycloalkenyl group; Z2 represents an atomic group for forming an aryl group, a heteroaryl group, a cycloalkenyl group or a heterocycloalkenyl group; Y represents an atomic group for forming a 5-membered nitrogen-containing heterocycloalkenyl group; each of R1, R2, R3 and R4 represents a hydrogen atom or a substituent; m is 1 or 2; a, b and d is 0 or any positive integer; and c is an integer of from 0 to 2.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: November 19, 2013
    Assignees: Chimei Innolux Corporation, National Tsing Hua University
    Inventors: Chien-Hong Cheng, Tai-Yen Chen, Hung-Hsin Shih, Chien-Te Wu, Kuan-Che Wang, Ching-In Wu, Huai-Ting Shih
  • Publication number: 20130296162
    Abstract: The present invention relates to novel micro or mesoporous metal organic frameworks (MOFs) which contain as ligands piperidine based phosphonic acids, as well as a method of synthesising such MOFs and uses of the MOFs themselves.
    Type: Application
    Filed: October 11, 2011
    Publication date: November 7, 2013
    Applicant: UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS
    Inventors: Paul A. Wright, Michael T. Wharmby, John P.S. Mowat
  • Patent number: 8574463
    Abstract: A metal complex dye, containing a ligand LL1 having a structure represented by Formula (I): wherein R1 and R2 represent a specific substituent; L1 and L2 represent a group composed of at least one kind of group selected from the group consisting of an ethenylene group, an ethynylene group and an arylene group, and conjugate with R1 or R2, and the bipyridine; the ethenylene group and the arylene group may be substituted or unsubstituted; R3 and R4 represent a substituent; n1 and n2 represent an integer of 0 to 3; A1 and A2 represent an acidic group or a salt thereof; and n3 and n4 represent an integer of 0 to 3.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: November 5, 2013
    Assignee: FUJIFILM Corporation
    Inventors: Yukio Tani, Tatsuya Susuki, Katsumi Kobayashi, Keizo Kimura
  • Patent number: 8557601
    Abstract: The present invention provides luminescent complexes between a lanthanide ion and an organic ligand which contains 1,2-hydroxypyridinone units. The complexes of the invention are stable in aqueous solutions and are useful as molecular probes, for example in medical diagnostics and bioanalytical assay systems. The invention also provides methods of using the complexes of the invention.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: October 15, 2013
    Assignee: The Regents of the University of California
    Inventors: Kenneth N. Raymond, Jide Xu, Evan G. Moore, Eric J. Werner
  • Publication number: 20130267483
    Abstract: This invention relates to complexes of certain divalent and polyvalent d-orbital metals of first transition series of the Periodic Table of Elements, from Group IV to Group VI, and including molybdenum, having a hydroxy acid [HA] and an amino acid [AA] moiety concurrently bound to a single said metal and having a spirocyclic, bidentate chelate structure of formula (I). Upon topical application said metal complexes undergo enhanced skin penetration without causing skin irritation.
    Type: Application
    Filed: February 6, 2013
    Publication date: October 10, 2013
    Applicant: BIODERM RESEARCH
    Inventor: SHYAM K GUPTA
  • Patent number: 8519130
    Abstract: Phosphorescent materials and devices with improved device manufacturing, fabrication, stability, efficiency, and/or color.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: August 27, 2013
    Assignee: Universal Display Corporation
    Inventor: Bert Alleyne
  • Publication number: 20130210793
    Abstract: The present invention provides compounds of Formula I: along with compositions comprising the same and methods of using the same, such as for photodynamic therapy in the treatment of cancer.
    Type: Application
    Filed: March 21, 2013
    Publication date: August 15, 2013
    Applicant: Duke University
    Inventor: Duke University
  • Publication number: 20130210615
    Abstract: Provided is a compound including residues derived from a compound represented by Formula (1) and a divalent aromatic group, wherein the number of the residues is 2 to 4, the number of the divalent aromatic group is 1 to 3, and the sum of the numbers of the residues and the divalent aromatic group is 3 to 5. In Formula (1), each of Y1 to Y4 represent a group represented by any of the following Formula (2); in the following Formula (2), R? represents a hydrogen atom or a hydrocarbyl group; each of P1 to P4 represents an atomic group forming a heterocyclic ring containing Y1 to Y4; P5 and P6 represent an atomic group forming an aromatic ring or a heterocyclic ring; Q1 and Q2 represent a linking group or a direct bond; and Z1 and Z2 represent a hydrogen atom or a group represented by any of the following Formula (3); and in the following Formula (3), R? represents a hydrogen atom or a hydrocarbyl group.
    Type: Application
    Filed: September 14, 2011
    Publication date: August 15, 2013
    Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED
    Inventor: Tadafumi Matsunaga
  • Publication number: 20130172524
    Abstract: The present invention provides bimetallic complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to one or more active metal centers of the complex.
    Type: Application
    Filed: September 14, 2011
    Publication date: July 4, 2013
    Applicant: NOVOMER, INC.
    Inventor: Jay J. Farmer
  • Publication number: 20130158267
    Abstract: Metal complex of Zinc(II) containing a dithio-based ligand have been synthesized and characterized by elemental analysis, mass spectrometry, Proton NMR and FT-IR spectrometry. A single crystal X-ray structure of the cadmium complex has been analyzed. The metal complex was subjected to biological tests on falcipain-2 (FP-2) and falcipain-3 (FP-3) cysteine protease enzymes from the malaria parasite Plasmodium falciparum. They were further tested in vitro against chloroquine resistant strain (W2). Whereas the potency of the metal complexes was weaker than the control regarding the FP-2 and FP-3, the potency of metal complexes was found to be exceedingly greater than the control when tested against the chloroquine resistant strain (W2) with a strength ratio of 172.4. This paper describes the synthesis, characterization and biological results of the said metal complex containing deprotonated 3-[1-(2-pyridyl) ethylidene] hydrazinecarbodithioate ligand.
    Type: Application
    Filed: November 19, 2010
    Publication date: June 20, 2013
    Inventor: Enos Kiremire
  • Publication number: 20130144031
    Abstract: The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.
    Type: Application
    Filed: January 31, 2013
    Publication date: June 6, 2013
    Applicant: NOVOMER, INC.
    Inventor: Novomer, Inc.
  • Publication number: 20130144032
    Abstract: The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.
    Type: Application
    Filed: January 31, 2013
    Publication date: June 6, 2013
    Applicant: NOVOMER, INC.
    Inventor: NOVOMER, INC.
  • Publication number: 20130144033
    Abstract: The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.
    Type: Application
    Filed: January 31, 2013
    Publication date: June 6, 2013
    Applicant: NOVOMER, INC.
    Inventor: Novomer, Inc.
  • Publication number: 20130137871
    Abstract: Metal complex of Manganese(II) containing a dithio-based ligand have been synthesized and characterized by elemental analysis, mass spectrometry, Proton NMR and FT-IR spectrometry. A single crystal X-ray structure of the cadmium complex has been analyzed. The metal complex was subjected to biological tests on falcipain-2 (FP-2) and falcipain-3 (FP-3) cysteine protease enzymes from the malaria parasite Plasmodium falciparum. They were further tested in vitro against chloroquine resistant strain (W2). Whereas the potency of the metal complexes was weaker than the control regarding the FP-2 and FP-3, the potency of metal complexes was found to be exceedingly greater than the control when tested against the chloroquine resistant strain (W2) with a strength ratio of 132.2 This paper describes the synthesis, characterization and biological results of the said metal complex containing deprotonated 3-[1-(2-pyridyl)ethylidene]hydrazinecarbodithioate ligand (FIG. 1).
    Type: Application
    Filed: November 19, 2010
    Publication date: May 30, 2013
    Inventor: Enos Kiremire
  • Publication number: 20130137872
    Abstract: Metal complex of Copper (II) containing a dithio-based ligand have been synthesized and characterized by elemental analysis, mass spectrometry, Proton NMR and FT-IR spectrometry. A single crystal X-ray structure of the copper complex has been analyzeThis paper describes the synthesis and characterization of the said metal complex containing deprotonated 3-[1-(2-pyridyl) ethylidene]hydrazinecarbodithioate ligand (FIG. 1).
    Type: Application
    Filed: November 19, 2010
    Publication date: May 30, 2013
    Inventor: Enos Kiremire
  • Patent number: 8440827
    Abstract: The present invention provides compounds of Formula I: (I) along with compositions comprising the same and methods of using the same, such as for photodynamic therapy in the treatment of cancer.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: May 14, 2013
    Assignee: Duke University
    Inventors: Katherine J. Franz, Katie L. Ciesienski
  • Patent number: 8436133
    Abstract: The present invention relates to the use of group 3 post-metallocene complexes based on sterically encumbered bis(naphthoxy)pyridine and bis(naphthoxy)thiophene ligands in the ring-opening polymerisation of polar monomers such as, for examples, lactones, lactides, cyclic carbonates.
    Type: Grant
    Filed: February 17, 2009
    Date of Patent: May 7, 2013
    Assignees: Total Petrochemicals Research Feluy, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Jean-François Carpentier, Evgueni Kirillov, Abbas Razavi
  • Publication number: 20130109662
    Abstract: The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use as medicaments, in particular for the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias.
    Type: Application
    Filed: March 22, 2011
    Publication date: May 2, 2013
    Applicant: Vifor (International) AG
    Inventors: Thomas Bark, Wilm Buhr, Susanna Burckhardt, Michael Burgert, Camillo Canclini, Franz Dürrenberger, Felix Funk, Peter Geisser, Aris Kalogerakis, Simona Mayer, Erik Philipp, Stefan Reim, Diana Sieber, Jörg Schmitt, Katrin Schwarz
  • Publication number: 20130096307
    Abstract: Metal complex of Cobalt (11) containing a dithio-based ligand have been synthesized and characterized by elemental analysis, mass spectrometry, Proton NMR and FT-IR spectrometry. A single crystal X-ray structure of the cadmium complex has been analyzed. The metal complex was subjected to biological tests on falcipain-2 (FP-2) and falcipain-3 (FP-3) cysteine protease enzymes from the malaria parasite Plasmodium falciparum. They were further tested in vitro against chloroquine resistant strain (W2). Whereas the potency of the metal complexes was weaker than the control regarding the FP-2 and FP-3, the potency of metal complexes was found to be exceedingly greater than the control when tested against the chloroquine resistant strain (W2) with a strength ratio of (0.5). This paper describes the synthesis, characterization and biological results of the said metal complex containing the deprotonated 3-[1-(2-pyridyl) ethylidene] hydrazinecarbodithioate ligand (FIG. 1).
    Type: Application
    Filed: November 19, 2010
    Publication date: April 18, 2013
    Applicant: UNIVERSITY OF NAMIBIA
    Inventor: Enos Kiremire
  • Publication number: 20130096308
    Abstract: Metal complex of Iron (U) containing a dithio-based ligand have been synthesized and characterized by elemental analysis, mass spectrometry, Proton NMR and FT-ER spectrometry. A single crystal X-ray structure of the cadmium complex has been analyzed. The metal complex was subjected to biological tests on falcipain-2 (FP-2) and falcipain-3 (FP-3) cysteine protease enzymes from the malaria parasite Plasmodium falciparum. They were further tested in vitro against chloroquine resistant strain (W2). Whereas the potency of the metal complexes was weaker than the control regarding the FP-2 and FP-3, the potency of metal complexes was found to be exceedingly greater than the control when tested against the chloroquine resistant strain (W2) with a strength ratio of (0.5). This paper describes the synthesis, characterization and biological results of the said metal complex containing deprotonated 3-[1-(2-pyridyl) ethylidene] hydrazinecarbodithioate ligand (FIG. 1).
    Type: Application
    Filed: November 19, 2010
    Publication date: April 18, 2013
    Inventor: Enos Kiremire
  • Publication number: 20130087203
    Abstract: A metal complex dye, containing a ligand LL1 having a structure represented by Formula (I): wherein R1 and R2 represent a specific substituent; L1 and L2 represent a group composed of at least one kind of group selected from the group consisting of an ethenylene group, an ethynylene group and an arylene group, and conjugate with R1 or R2, and the bipyridine; the ethenylene group and the arylene group may be substituted or unsubstituted; R3 and R4 represent a substituent; n1 and n2 represent an integer of 0 to 3; A1 and A2 represent an acidic group or a salt thereof; and n3 and n4 represent an integer of 0 to 3.
    Type: Application
    Filed: November 29, 2012
    Publication date: April 11, 2013
    Applicant: FUJIFILM CORPORATION
    Inventor: Fujifilm Corporation
  • Publication number: 20130045961
    Abstract: Personal care compositions including dried zinc pyrithione are provided.
    Type: Application
    Filed: August 15, 2012
    Publication date: February 21, 2013
    Inventors: Edward Dewey SMITH, III, Jason Edward COOK
  • Publication number: 20130001535
    Abstract: The present invention provides a light-emitting organic platinum complex, a light-emitting material containing this complex, and a functional device containing this complex. The light-emitting organic platinum complex is represented by any one of the following structural formulae: where: Z represents either —(CH2)n— or —CH2(CH2OCH2)mCH2—, where n represents 7 to 14, and m represents 3 to 4; A represents either an optionally condensed aromatic hydrocarbon ring or an optionally condensed heteroaromatic ring; R is a substituent group for A and represents H (unless n of Z in the structural formula (1) is 7 to 13), a halogen, a C1-C6 alkyl group, a C1-C6 alkenyl group, a C1-C6 alkynyl group, a C1-C6 alkoxy group or the like.
    Type: Application
    Filed: February 18, 2011
    Publication date: January 3, 2013
    Applicant: OSAKA UNIVERSITY
    Inventors: Takeshi Naota, Naruyoshi Komiya, Minoru Okada
  • Publication number: 20120269724
    Abstract: The present invention relates to compounds and related technetium and rhenium complexes thereof which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled metal complexes, particularly tissues, organs, or tumors which express certain receptors to which the compounds or complexes of the invention have an affinity. The present invention also relates to methods of treating cancer, particularly those cancer lines which express certain receptors to which the compounds or complexes of the invention have an affinity. In yet another embodiment, the present invention provides methods of imaging and/or inhibiting receptors or neuroreceptors using compounds or complexes of the invention which have an affinity for the receptor or neuroreceptor to be imaged and/or inhibited.
    Type: Application
    Filed: December 13, 2011
    Publication date: October 25, 2012
    Applicant: President and Fellows of Harvard College
    Inventors: Ashfaq Mahmood, Alun G. Jones, Naengnoi Limpa-Amara, Yijie Peng, Zeynep Akgun
  • Publication number: 20120264939
    Abstract: Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials, dental bonding agents or other dental materials, to produce materials with high fluoride release rates, and high fluoride recharge capability. Such dental restorative materials may help reduce the level of dental caries in patients, particularly the level of caries occurring on the margins of the restorative materials.
    Type: Application
    Filed: May 30, 2012
    Publication date: October 18, 2012
    Inventors: Xiaoming Xu, Shailaja Jayaramachandran, Liang Chen
  • Publication number: 20120260433
    Abstract: Metal bleach catalysts that are complexes of a transition-metal and a dioxo ligand, cleaning compositions comprising such metal bleach catalysts, and methods of using such metal bleach catalysts, are described herein.
    Type: Application
    Filed: April 11, 2012
    Publication date: October 18, 2012
    Inventors: David Tétard, Adam Phillip Robinson-Miller, Robert Richard Dykstra, Gregory Scot Miracle
  • Publication number: 20120238752
    Abstract: Provided is a colored photosensitive curing composition useful for color filters in primary colors, including blue, green, and red, having a high molar absorption coefficient and allowing a reduction in film thickness and superior color purity and fastness. A colored photosensitive curing composition, comprising, as its colorant, a dipyrromethene-based metal complex compound obtained from a metal or metal compound and a dipyrromethene-based compound represented by the following Formula (I): wherein in Formula (I), R1 to R6 each independently represent a hydrogen atom or a substituent group; and R7 represents a hydrogen or halogen atom, or an alkyl, aryl or heterocyclic group.
    Type: Application
    Filed: May 23, 2012
    Publication date: September 20, 2012
    Applicant: FUJIFILM CORPORATION
    Inventors: Yuki MIZUKAWA, Ryoji GOTO, Hideki TAKAKUWA, Masashi OGIYAMA, Toru FUJIMORI