Abstract: The present invention relates to self-regenerating antioxidant catalysts and methods of using the same.

Abstract: The present invention relates to a radiotracer precursor for imaging of hypoxic tissues, a radiotracer and a method for preparing the same. The radiotracer precursor, BANI, includes a nitroimidazole functional group with a feature of retention in hypoxic tissues and a bifunctional ligand able to complex with radioisotopes. Thus BANI can be used to produce radiotracers retained in hypoxic tissues and the radiotracers are applied to medical imaging of malignant tumor with hypoxic layer.

Abstract: The present invention relates to metal thiourea complexes comprising N-substituted thiourea ligands and sulfur-coordinated metal ions, and methods for using the metal thiourea complexes for delivering otherwise unstable or impermeable metal ions to mammalian cells, for inhibiting cancer cell growth and inflammation, and for inhibiting the activities of associated drug targets under in vitro and in vivo conditions. The metal complexes of N-substituted thiourea are defined by the following formula (Ia or Ib) wherein R1 can be H, alkyl, alkenyl, alkynyl, aryl or heterocyclic groups; R2 can be H, alkyl, alkenyl, alkynyl or aryl groups; n=1 to 4; X? is a pharmaceutically acceptable anion (chloride, bromide, iodide, hexafluorophosphate, or triflate) and M is a coinage metal (Au, Ag, or Cu).

Abstract: The present invention relates to specific metal complexes of dithiolenes with perfluoroalkyl substituted imidazolidine-2-chalcogenone-4,5-dithione ligands, a process for their preparation and their use as colourless IR absorbers, for optical filters application; especially for plasma display panels, or for laser welding of plastics. The compounds may be used in compositions for inks, paints and plastics, especially in a wide variety of printing systems and are particularly well-suited for security applications.

Abstract: An iridium complex is disclosed, which has a structure represented by the following formula (I): wherein each of Z1 and Z3 represents an atomic group for forming a nitrogen-containing heteroaryl group or a nitrogen-containing heterocycloalkenyl group; Z2 represents an atomic group for forming an aryl group, a heteroaryl group, a cycloalkenyl group or a heterocycloalkenyl group; Y represents an atomic group for forming a 5-membered nitrogen-containing heterocycloalkenyl group; each of R1, R2, R3 and R4 represents a hydrogen atom or a substituent; m is 1 or 2; a, b and d is 0 or any positive integer; and c is an integer of from 0 to 2.

Abstract: Disclosed are compounds having one of the following formulae: wherein X is an aromatic nucleophilic substitution leaving group; R1 is hydrogen, an alkyl group, or an aryl group; and Q1 is a carboxyl protecting group or an aldehyde protecting group. Also disclosed are fused thiophenes that can be prepared using these compounds, as well as stannylthio-containing thiophene, thienothiophene, and dithienothiophene compounds that can be used to prepare fused thiophenes. Methods for making and using the aforementioned compounds, fused thiophenes, and stannylthio-containing thiophene, thienothiophene, and dithienothiophene compounds are also disclosed.

Abstract: The present invention relates to the use of specific metal complexes of dithiolenes with aryl or heteroarylsubstituted imidazolidine-2-chalcogenone-4,5-dithione ligands as colourless IR absorbers.

Abstract: The present invention relates to metal thiourea complexes comprising N-substituted thiourea ligands and sulfur-coordinated metal ions, and methods for using the metal thiourea complexes for delivering otherwise unstable or impermeable metal ions to mammalian cells, for inhibiting cancer cell growth and inflammation, and for inhibiting the activities of associated drug targets under in vitro and in vivo conditions. The metal complexes of N-substituted thiourea are defined by the following formula (Ia or Ib) wherein R1 can be H, alkyl, alkenyl, alkynyl, aryl or heterocyclic groups; R2 can be H, alkyl, alkenyl, alkynyl or aryl groups; n=1 to 4; X? is a pharmaceutically acceptable anion (chloride, bromide, iodide, hexafluorophosphate, or triflate) and M is a coinage metal (Au, Ag, or Cu).

Abstract: The present invention relates to heteroleptic electroluminescent metal complexes and to their preparation and use in electroluminescent devices, particularly to electroluminescent compounds having the general chemical formula:

Abstract: Disclosed are compounds having one of the following formulae (11), (12), wherein X is an aromatic nucleophilic substitution leaving group; R1 is hydrogen, an alkyl group, or an aryl group; and Q1 is a carboxyl protecting group or an aldehyde protecting group. Also disclosed are fused thiophenes that can be prepared using these compounds, as well as stannylthio-containing thiophene, thienothiophene, and dithienothiophene compounds that can be used to prepare fused thiophenes. Methods for making and using the aforementioned compounds, fused thiophenes, and stannylthio-containing thiophene, thienothiophene, and dithienothiophene compounds are also disclosed.

Abstract: To provide a squarylium compound forming a metal complex, expressed by the general formula (I): where R1 and R2 are the same or different and each of R1 and R2 represents a substituted or unsubstituted alkyl, aralkyl, aryl, or heterocyclic group; Q represents a metal atom having coordinating ability; q represents 2 or 3; R3 represents a substituted or unsubstituted aralkyl, or aryl group; R4 represents a substituted or unsubstituted alkyl, aralkyl, or aryl group,’ R5 represents a hydrogen atom, or substituted or unsubstituted alkyl, aralkyl, or aryl group; R6 represents a halogen atom, nitro group, cyano group, or substituted or unsubstituted alkyl, aralkyl, aryl, or alkoxy group; p represents any integer ranging from 0 to 4; and RGs are the same or different and any adjacently located two R6s optionally form a substituted or unsubstituted aromatic ring together with two adjacent carbon atoms when p is 2, 3 or 4.

Abstract: A recording layer including a novel organic dye compound (I) for a high density optical recording medium is provided. The organic dye compound (I) has the following general chemical structural formula: wherein R1, R2, R3, R4 and R5 each independently represent H, alkyl, halide, nitro, benzyl group or substituted benzyl group. The organic dye compound (I) exhibits a maximum absorbance at a wavelength range of 400-550 nm.

Abstract: A recording layer including a novel organic compound for a high density optical recording medium is provided. The information may be recorded on the recording layer at a 2× speed or higher speed with a relatively lower writing power so that heat distribution of the recording layer in the irradiated area is not likely to become steep both in time and space. The organic compound incorporated in the recording layer has the following general chemical structural formula (I).

Abstract: Disclosed are colorant compounds of the formulae wherein R1, R2, R3, M, A, E, G, J, m, n, and p are as defined herein.

Abstract: An electroluminescent material is a metal complex, preferably aluminium, of a substituted pyrazol-5-one.

Abstract: A series of dynamic platinum compounds for cancer treatment are described. The compounds may become active and inactive reversibly.

Abstract: Thermally developable materials such as thermographic and photothermographic materials include a co-precipitate comprising first and second organic silver salts, the first organic silver salt comprising a silver salt of a nitrogen-containing heterocyclic compound containing an imino group, and the second organic silver salt comprising a silver salt of a mercaptotriazole. The first organic silver salt can be used in the imaging process as a source of reducible silver ions, and the second organic silver salt can be a source of a toning agent. The co-precipitate can be prepared using double-jet precipitation techniques to provide an aqueous dispersion that can be used in imaging formulations.

Abstract: New ruthenium dimeric complexes with high antimetastatic and antitumour activity and remarkable chemical stability are described.

Abstract: The present invention relates to novel hexacoordinated metathesis catalysts and to methods for making and using the same. The inventive catalysts are of the formula wherein: M is ruthenium or osmium; X and X1 are the same or different and are each independently an anionic ligand; L, L1′ and L2 are the same or different and are each independently a neutral electron donor ligand; and, R and R1 are each independently hydrogen or a substituent selected from the group consisting of C1-C20 alkyl, C2-C20 alkenyl, C2-C20 alkynyl, aryl, C1-C20 carboxylate, C1-C20 alkoxy, C2-C20 alkenyloxy, C2-C20 alkynyloxy, aryloxy, C2-C20 alkoxycarbonyl, C1-C20 alkylthio, C1-C20 alkylsulfonyl and C1-C20 alkylsulfinyl and silyl.

Abstract: This invention relates to an organothiosulfonato Au(I) complex having the formula

Abstract: An object of the present invention is to provide a material having spectroscopic properties, light resistance, solubility and thermal decomposition properties suitable for recording for DVD-R. More specifically, the present invention provides squarylium compounds in a state of a metal complex represented by the general formula (I): wherein, R1 and R2 are the same or different, and represent an alkyl group optionally having a substituent, an aralkyl group optionally;,having a substituent, an aryl group optionally having a substituent, or a heterocyclic group optionally having a substituent; Q represents a metal atom with a coordination ability; q represents 2 or 3; and A represents an aryl group optionally having a substituent, a heterocyclic group optionally having a substituent, or Y═CH— wherein Y represents an aryl group optionally having a substituent or a heterocyclic group optionally having a substituent.

Abstract: A composition comprising (a) a metal complex of a cyclic thiohydroxamic acid such as the 2:1 zinc complex of 3-hydroxy-4-methylthiazol-2(3H)-thione and (b) a salt of the metal such as zinc chloride, acetate or oxide. The presence of component (b) gives enhanced microbiological activity.

Abstract: Hexacoordinated ruthenium and osmium catalysts of the formulae ##STR1## in which M and M' independently of one another are ruthenium or osmium;X, X', Y and Y' independently of one another are anionic ligands, or X and Y and X' and Y' in each case together are bis-anionic ligandsL.sup.1 and L.sup.1' independently of one another are tertiary phosphine;L.sup.2 and L.sup.3 independently of one another are a monodentate ligand, or L.sup.2 and L.sup.3 together are bidentate, neutral electron donor ligands;L.sup.4 is tetradentate, neutral electron donor ligand;L.sup.5 is a bidentate, neutral electron donor ligand; andT and T' indepedently of one another are H or organic substituents, are useful for the synthesis of custom-tailored polymers and for the ring-closing metathesis of olefins.

Abstract: The present invention relates to the treatment of tumors with a novel water soluble trans-platinum coordination compound having the general structural formula [PtBX.sub.m (NR*.sub.3)] where B is a planar, heterocyclic ring containing at least one nitrogen atom, and a pendant chelating group; and X is an anionic ligand; and R* is hydrogen or a lower alkyl.

Abstract: A novel metallocene catalyst for the polymerization of olefin (co)polymers is of the general formula:Benzothiazole--E--M--X.sub.m L.sub.nwhere,M is a transition metal of Groups 3-10 of the Periodic Table;E is sulfur or oxygen; E being bond to the transition metal and to the carbon atom between sulfur and nitrogen of the benzothiazole moiety;L is a polymerization-stable anionic ancillary ligand;X is a halogen, alkoxy from C.sub.1 to C.sub.20, siloxy from C.sub.1 to C.sub.20, N(R.sub.1).sub.2, a hydrocarbyl group containing up to about 12 carbon atoms or hydrogen or mixtures thereof; preferably X is halogen, methoxy, ethoxy or siloxy (R.sub.1).sub.3 SiO--, where R.sub.1 is alkyl from C.sub.1 to C.sub.20 ; andm+n equals the valency of the M minus 1.

Abstract: The invention is a compound of the formula: ##STR1## wherein M is a bivalent or trivalent metal ion, and X is OH or O.sup..crclbar.. The above compound of the present invention is useful for prevention or treatment of mycoplasmosis.

Abstract: Compounds having a 5 membered, nitrogen containing ring with a thione group adjacent to a nitrogen atom substituted with an OR group have antimicrobial properties. Metal complexes or salts of these compounds also have antimicrobial properties. The compounds, or the metal complexes or salts thereof, can be used as a cutting fluid preservative, a wood preservative, in cooling water applications or as an antimicrobial agent in a paint. Some of the compounds are new. The metal complexes or salts are new.

Abstract: 2,4-Heteroatom-substituted-molybdena-3,3-dioxocyclopentane hydro-conversion catalysts are disclosed. In some embodiments, inexpensive bulk catalysts in accordance with the present invention are synthesized from bulk triglyceridic epoxides or fatty acids.

Abstract: A photographic silver halide material is chemically sensitized with a soluble gold(I) compound of the formula:AuL.sub.2.sup.+ X.sup.-orAuL(L.sup.1).sup.+ X.sup.-wherein L is a mesoionic compound; X is an anion; and L.sup.1 is Lewis donor ligand. The novel gold(I) compounds possess properties which are advantageous compared to the properties of previously known gold compounds.

Abstract: Metal complexes of azines of the formula ##STR1## in which X denotes hydrogen or halogen,R denotes hydrogen or an organic radical,R.sub.1 denotes hydrogen or an organic radical,R.sub.2 denotes an organic radical, in which R.sub.1 and R.sub.2 together with the C atom linking them can also form a carbocyclic or heterocyclic ring or a carbocyclic or heterocyclic ring system in which the rings and ring systems mentioned can also be substituted, and one of the radicals R.sub.1, R.sub.2 or R.sub.1 and R.sub.2 together contain a group capable of forming a metal salt, and processes for pigmenting using these metal complexes.

Abstract: A chiral catalyst is disclosed together with methods of using it for enantioselective syntheses. The chiral catalyst includes a nucleus with two metal atoms that has four bridging ligands oriented radially to the axis of the nucleus. Each of these ligands includes two complexing atoms each complexed to one of the metal atoms. At least one of the bridging ligands includes a chiral center which is bonded to one of the complexing atoms. Preferably, all four of the bridging ligands include a chiral center bonded to one of the complexing atoms. The catalyst of the invention has been found to be useful in catalyzing carbenoid transformation reactions such as cyclopropanation.

Abstract: Compounds of the formulae: ##STR1## and pharmaceutically acceptable salts, esters and prodrugs thereof, wherein M and R.sub.1 are independently selected from among optionally substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl, aryl, arylalkyl, arylalkenyl, reduced heteroaryl and reduced heteroarylalkyl groups, andZ is the residue of a compound selected from the class of compounds known as non-steroidal antiinflammatory grugs containing a carboxylic acid group, of the general form Z-COOH.

Abstract: Azine pigment which has one of the possible tautomeric forms of the formula I ##STR1## and which is present in its c-crystalline modification, which is characterized by the interplanar spacings (relative intensity) 3.29 (100); 3.60 (24); 3.73 (28); 4.64 (28); 6.23 (31); 6.97 (23); 8.05 (67); 9.36 (34); 12.63 (67); 13.96 (32) and 16.35 (30).This pigment is excellently suitable for coloring high-molecular weight organic material, in particular automobile paints.

Abstract: This invention relates to novel compositions of matter which are multifunctional amino zirconium aluminum metallo organic complexes which are comprised of a chemically united complex aluminum moiety, a tetravalent zirconium moiety, and a multifunctional amino acid wherein the acid is chemically bound to both the aluminum and zirconium centers.Such compositions are useful in promoting adhesion of adhesives, sealants, and coatings to metal, rubber, glass, plastic, coatings, and wood thereby enhancing strength properties and prolonging useful service life when such products are exposed to aggressive environments.Futher described is the specific process for the preparing of such compositions in organic media with desirable stability of the metal centers toward polymerization and related hydrolysis.

Abstract: Compounds of the formula ##STR1## wherein Het is a 5- or 6-membered aromatic heterocyclic ring containing 1 to 2 ring nitrogen atoms and the remaining ring atoms carbon atoms optionally substituted with 1 to 2 substituents independently selected from halo, nitro, trihalomethyl, lower alkyl of 1 to 3 carbon atoms, or lower alkoxy of 1 to 3 carbon atoms; R is alkyl of 1 to 7 carbon atoms; R.sup.1 is aryl of 6 to 10 carbon atoms, lower alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, all optionally substituted with 1 to 3 halogen atoms; and a is 0 or 1 are fungicidal and insecticidal, with the proviso that a ring nitrogen is not bonded to the hydroxamic acid ##STR2## moiety.

Abstract: Pigments of the formula ##STR1## in which Me=Zn, Cu, Co or preferably Ni,R=alkyl, cycloalkyl, aralkyl, aryl and hetaryl, where the mentioned radicals can be substituted, andAr=optionally substituted aryl,processes for their preparation, and their use.

Abstract: A new crystalline zirconium phosphate composition and method for its synthesis are provided. The composition has ion exchange properties and is readily convertible to catalytically active material by thermal treatment.

Abstract: Pigments which, in one of their tautomeric forms, have the formula ##STR1## in which R signifies --CH.sub.3 or ##STR2## and which, in the event that R is --CH.sub.3, are present in the .beta.-modification which is characterized by the lattice plane spacings d/.ANG. 13.33, 12.67, 9.17 and 15.15 having the relative intensities 100, 100, 60 and 2%, process for their preparation and their use.

Abstract: Novel copper (II) coordination complexes of 3,5-dioxo-pyrazolidine derivatives with dimethylsulphoxide, dimethylformamide, and 1,4-dioxan coordination ligands are described. The complexes are potent anti-inflammatory agents and are usually applied topically in non-aqueous solution, showing good dermal penetration and systemic absorption.

Abstract: The metal salts of 1,2,4-thiadiazole having the structure ##STR1## and lubricants containing said metal salts are provided.

Abstract: The invention relates to a simplified process for the manufacture of 1:1 metal complexes of isoindoline azines of the formula ##STR1## wherein R is hydrogen, alkyl or aryl, Q contains an isocyclic or heterocyclic radical, acyl, carbamoyl or thiocarbamoyl, and Y is the radical of an active methylene group or aromatic amine, which comprises reacting a compound HQ or a hydrazone with an ortho ester or amidine in the presence of a metal donor at elevated temperature in a polar solvent. Pigments made by this process are lightfast and are useful in coloring plastics.

Abstract: Process for the preparation of 1:1 metal complexes of azines of the formula ##STR1## in which R.sub.1 is an H atom or an alkyl or aryl group, R.sub.2 is an isocyclic or heterocyclic radical with a hydroxyl or mercapto group adjacent to the azomethine group, Y' is the radical of a methylene-active compound or of an aryl-or heteroaryl-amine and the ring A can have substituents which do not confer solubility in water, which comprises heating a hydrazone of the formula ##STR2## with an isoindolinone of the formula ##STR3## in which R.sub.1, R.sub.2, A and Y' are as defined, in the presence of a metal donor, in a polar organic solvent.

Abstract: 1:1 Nickel complexes of azines of the formula I or of a tautomer thereof ##STR1## wherein R.sub.1 is hydrogen or methyl, R.sub.2 is methyl or carbamoyl, R.sub.3 is hydrogen or chlorine, R.sub.4 is hydrogen, chlorine, methyl, trifluoromethyl or sulfamoyl, R.sub.5 is hydrogen or chlorine, R.sub.6 is hydrogen, chlorine, bromine, methyl, methoxy, trifluoromethyl, carbamoyl or alkanoylamino containing 2 to 4 carbon atoms, with the proviso that, if R.sub.2 is carbamoyl, at least two of the substituents R.sub.3 to R.sub.6 are halogen atoms and/or trifluoromethyl groups, color plastics, lacquers and printing inks in orange to red shades of outstanding fastness properties.

Abstract: Herbicidally active compound having the formula ##STR1## wherein R.sub.1 represents hydrogen atom or a lower alkyl group,R.sub.2 represents a lower alkyl group or a lower alkenyl group,X represents a variety of substituents of the phenyl ring, andY represents oxygen or sulfur, and the salts and organic acid esters thereof.

Abstract: The invention relates to a simplified process for the manufacture of 1:1 metal complexes of isoindoline azines of the formula ##STR1## wherein R is hydrogen, alkyl or aryl, Q contains an isocyclic or heterocyclic radical, acyl, carbamoyl or thiocarbamoyl, and Y is the radical of an active methylene group or aromatic amine, which comprises reacting a compound HQ or a hydrazone with an ortho ester or amidine in the presence of a metal donor at elevated temperature in a polar solvent. Pigments made by this process are lightfast and are useful in coloring plastics.

Abstract: 1:1 metal complexes of isoindolinazines of the formula ##STR1## in which the ring A can be further substituted, R is a hydrogen atom or an alkyl or aryl group, B is an isocyclic or heterocyclic aromatic radical, R.sub.1 is the OH or SH group and Y is a radical of the formula ##STR2## in which Z.sub.1 and Z.sub.2 are O or S atoms, n is the number 1 or 2, R.sub.2 ' is an alkyl, aryl or heteroaryl radical and R.sub.2 is an alkyl, cycloalkyl, aralkyl or aryl radical or a radical of the formula ##STR3## in which R.sub.3 is an alkylene or arylene group. The novel pigments color plastics and surface coatings in pure, intense orange to red shades with good fastness properties.

Abstract: 1:1 metal complexes of azines of the formula ##STR1## in which the ring A can be further substituted, R is an H atom or an alkyl or aryl group, B is an isocyclic or heterocyclic aromatic radical or an alicyclic radical, R.sub.1 is the OH or SH group and Y is a radical of the formula ##STR2## in which Z is an O or S atom, n is the number 1 or 2 and R.sub.2 is an alkyl, aralkyl, cycloalkyl or aryl radical or an amino group which is unsubstituted or substituted by an alkyl, cycloalkyl, aralkyl or aryl radical.In plastics and surface coatings, the novel pigments give intense pure orange to violet colorations with good fastness properties.

Abstract: 1:1 Nickel complexes of azines of the formula I or of a tautomer thereof ##STR1## wherein R.sub.1 is hydrogen or methyl, R.sub.2 is methyl or carbamoyl, R.sub.3 is hydrogen or chlorine, R.sub.4 is hydrogen, chlorine, methyl, trifluoromethyl or sulfamoyl, R.sub.5 is hydrogen or chlorine, R.sub.6 is hydrogen, chlorine, bromine, methyl, methoxy, trifluoromethyl, carbamoyl or alkanoylamino containing 2 to 4 carbon atoms, with the proviso that, if R.sub.2 is carbamoyl, at least two of the substituents R.sub.3 to R.sub.6 are halogen atoms and/or trifluoromethyl groups, color plastics, lacquers and printing inks in orange to red shades of outstanding fastness properties.

Abstract: A chiral catalyst is disclosed together with methods of using it for enantioselective syntheses. The chiral catalyst includes a nucleus with two metal atoms that has four bridging ligands oriented radially to the axis of the nucleus. Each of these ligands includes a two complexing atoms each complexed to one of the metal atoms. At least one of the bridging ligands includes a chiral center which is bonded to one of the complexing atoms. Preferably, all four of the bridging ligands include a chiral center bonded to one of the complexing atoms. The catalyst of the invention has been found to be useful in catalyzing carbenoid transformation reactions such as cyclopropanation.

Abstract: A new crystalline zirconium phosphate composition and method for its synthesis are provided. The composition has ion exchange properties and is readily convertible to catalytically active material by thermal treatment.