Boron Or Silicon Containing Patents (Class 548/110)
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Patent number: 12122765Abstract: The present disclosure relates to methods and intermediates useful for preparing a compound of formula I: or a co-crystal, solvate, salt or combination thereof.Type: GrantFiled: June 5, 2023Date of Patent: October 22, 2024Assignee: Gilead Sciences, Inc.Inventors: Anna Michelle Wagner, Scott Alan Wolckenhauer
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Patent number: 12000846Abstract: Nitrogen containing compounds may have formulas (I), (II) and (IV), and such compounds may be suitable for detecting alkyne group containing organic compounds by mass spectrometry. Furthermore, methods may also include synthesizing these compounds, detecting of organic compounds containing the specific compounds, uses of the compounds in mass spectrometry for determining enzyme activity or monitoring the lipid metabolism in a cell, and a kit which contains at least one of these compounds and at least one internal standard.Type: GrantFiled: June 28, 2019Date of Patent: June 4, 2024Assignee: Rheinische Friedrich-Wilhelms-Universitaet BonnInventor: Christoph Thiele
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Patent number: 11655368Abstract: A condensation curable silicone adhesive composition comprising a condensation curable organopolysiloxane, siloxane-imide crosslinker, a condensation catalyst and an additive is shown and described herein. The composition is curable at relatively room temperatures and shows good heat stability.Type: GrantFiled: December 23, 2020Date of Patent: May 23, 2023Assignee: Momentive Performance Materials Inc.Inventors: Subrata Mandal, Tetsuo Fujimoto, Vinodh Rajendra, Debanga B. Konwar, Clarissa Miller, Kaka Dey
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Patent number: 11638428Abstract: Disclosed are compounds of Formulae 1, 1a, 1b and 2, wherein R1, R1a, R1b, R2, R3 and R4 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formulae 1, 1a and 1b, and methods for controlling a parasitic nematode comprising contacting the parasitic nematode or its environment with a biologically effective amount of a compound or composition of Formulae 1, 1a, 1b and 2.Type: GrantFiled: September 14, 2020Date of Patent: May 2, 2023Assignee: CORTEVA AGRISCIENCE LLCInventors: George Philip Lahm, Andrew Jon Deangelis, Matthew James Campbell
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Patent number: 11543412Abstract: The present disclosure relates to biosensors, kits and methods for detecting and/or quantifying lysophosphatidic acid (LPA) in a liquid sample such as a serum sample from a subject. The present disclosure also relates to linker compounds that are useful, for example, in the biosensors, kits and methods of the present disclosure and to methods for preparing a biosensor for detecting and/or quantifying lysophosphatidic acid (LPA) in a liquid sample.Type: GrantFiled: June 10, 2020Date of Patent: January 3, 2023Assignee: Thompson Surface Innovations CorporationInventors: Brian De La Franier, Michael Thompson
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Patent number: 11342511Abstract: An object is to provide an azoline ring-containing compound which achieves characteristics required for an organic EL element, such as a driving voltage, a quantum efficiency, and element lifetime in a well-balanced manner, and particularly can obtain a high quantum efficiency, for example, in a case where the azoline ring-containing compound is used for the organic EL element. The above object is achieved by an azoline ring-containing compound represented by the following general formula (1). In formula (1), ? represents an m-valent group derived from an aromatic hydrocarbon having 6 to 40 carbon atoms or the like, Y represents —O—, —S—, or >N—Ar, R1 to R5 each represent a hydrogen atom or an alkyl having 1 to 4 carbon atoms, and L represents a phenylene group or the like.Type: GrantFiled: July 20, 2016Date of Patent: May 24, 2022Assignee: SK MATERIALS JNC CO., LTD.Inventors: Daisuke Baba, Yohei Ono, Katsuya Masuda
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Patent number: 11186768Abstract: The invention relates to the use of one or more compounds of the 4-bora-3a,4a-diaza-s-indacene family for the preparation of a security element for a product, in particular a document, said security element comprising a polymer and said compound(s) being incorporated in said polymer, and to a method for ensuring the security of a product, in particular that of a document.Type: GrantFiled: January 9, 2017Date of Patent: November 30, 2021Assignee: CRIME SCIENCE TECHNOLOGYInventor: Cosimo Prete
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Patent number: 11104693Abstract: The present disclosure is directed to methods for dehydrogenatively coupled hydrosilanes and alcohols, the methods comprising contacting an organic substrate having at least one organic alcohol moiety with a mixture of at least one hydrosilane and sodium and/or potassium hydroxide, the contacting resulting in the formation of a dehydrogenatively coupled silyl ether. The disclosure further described associated compositions and methods of using the formed products.Type: GrantFiled: April 15, 2019Date of Patent: August 31, 2021Assignee: California Institute of TechnologyInventors: Anton Toutov, Kerry Betz, Andrew M. Romine, Robert H. Grubbs
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Patent number: 10954436Abstract: The present invention relates to the use, as a fluorescent chromophore, of a compound with formula (I) wherein: A1 is —N— or —C(Y1)—; A2 is —N— or —C(Y2)—; A3 is —N— or —C(Y3)—; A4 is —N— or —C(Y4)—; at least one of A1, A2, A3 and A4 representing —N—; X1 is —N— or —C(Y5)—; X2 is —N— or —C(Y6)—; X3 is —N— or —C(Y7)—; and Y1, Y2, Y3, Y4, Y5, Y6 and Y7 are in particular chosen independently of one another from the group made up of: H, electron-donor groups and electron-attracting groups.Type: GrantFiled: July 19, 2016Date of Patent: March 23, 2021Assignees: UNIVERSITE D'ORLEANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Franck Suzenet, Doina Sirbu, Gérald Guillaumet, Pascal Bonnet
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Patent number: 10676490Abstract: Disclosed is a method of delivering therapeutic carbon monoxide to the cells and tissues of a patient which comprises administering thereto a compound of the formula XBY1Y2C(O)V (I) or pharmaceutically acceptable salts thereof. In addition, disclosed is a method of delivering a drug to a diseased cell or tissue by administering a compound of formula I either wherein at least one of X is a drug containing an amino group or V is a drug containing an amino group or hydroxyl group less a hydrogen on the amino or hydroxyl group. Further disclosed are novel compounds of Formula I.Type: GrantFiled: July 7, 2016Date of Patent: June 9, 2020Assignees: Florida Southwestern State College, The Research Foundation for the State University of New York, University of Alaska AnchorageInventors: Nin N. Dingra, Theppawut Israsena Na Ayudhya
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Patent number: 10336615Abstract: The present invention provides a titanium ligand-modified black phosphorus and the preparation method and use thereof. The titanium ligand-modified black phosphorus is a complex of black phosphorus and a titanium ligand having a structure represented by formula (I): wherein in the formula (I), R1 comprises C1-C6 alkyl, or phenyl optionally further substituted with 0 to 5 groups each independently selected from halogen atom, C1-C6 alkyl, nitro, hydroxy, amino or C1-C3 alkoxy; the C1-C6 alkyl or C1-C3 alkoxy is optionally further substituted with 0 to 3 groups each independently selected from halogen atom, nitro, hydroxy, amino, methyl, ethyl or n-propyl. The titanium ligand-modified black phosphorus of the present invention is not likely oxidized without changing inherent properties of the black phosphorus, and the antioxidant capacity is greatly enhanced.Type: GrantFiled: December 23, 2016Date of Patent: July 2, 2019Assignee: SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGYInventors: Huaiyu Wang, Yuetao Zhao, Xuefeng Yu
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Patent number: 10258608Abstract: The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.Type: GrantFiled: June 28, 2017Date of Patent: April 16, 2019Assignee: DISPERSOL TECHNOLOGIES, LLCInventors: Dave A. Miller, Justin M. Keen, Sandra U. Kucera
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Patent number: 9945038Abstract: Provided are a method of producing corrosion-protective copper paste through a single process and an application thereof to a dipole tag antenna. Copper powder is surface-etched by using a hydrochloric acid in an inert gas atmosphere, a phosphoric acid aqueous solution is added thereto to form copper phosphate on the etched surface of the copper powder, and then, a vinyl imidazole-silane copolymer and poly(4-styrenesulfonate) were introduced thereto to form a corrosion-protective coating layer on the surface of copper powder on which the copper phosphate has been formed, and a centrifuge and an agate mortar are used to prepare a copper paste having high viscosity and high dispersability. When a copper paste thin film is formed on a flexible film by screen printing, a produced dipole tag antenna may have high efficiency.Type: GrantFiled: May 27, 2014Date of Patent: April 17, 2018Assignee: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATIONInventors: Jyongsik Jang, Keunyoung Shin
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Patent number: 9935336Abstract: A secondary battery includes: a cathode including a lithium-oxygen-containing compound; an anode; and non-aqueous electrolytic solution including one or more first anions represented by Formula (1). B(XY)xFyRz-??(1) where X is one of a divalent chain hydrocarbon group, a divalent fluorinated chain hydrocarbon group, and nothing; Y is one of a cyano group (—C?N) and an isocyano group (—N+?C—); R is one of a monovalent fluorinated chain hydrocarbon group and a monovalent fluorinated cyclic hydrocarbon group; and x to z are integers that satisfy x>0, y?0, z?0, (x+y+z)=4, and (y+z)>0.Type: GrantFiled: November 7, 2014Date of Patent: April 3, 2018Assignee: MURATA MANUFACTURING CO., LTD.Inventors: Masayuki Ihara, Shigeru Fujita
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Patent number: 9935338Abstract: An object of the present invention is to provide a liquid electrolyte for a fluoride ion battery allowing a reaction between an active material and a fluoride ion. By providing a liquid electrolyte for a fluoride ion battery comprising: a fluoride salt; and a sulfonium compound having a cation in which R1, R2, and R3 (R1, R2, and R3 each independently represent hydrogen, an alkyl group, or a fluoroalkyl group) are bound to the S element, and an anion, wherein the molar ratio of the cation relative to the total of the cation and the fluoride ion (S+/(S++F?)) is 0.96 or more, the present invention achieves the aforementioned object.Type: GrantFiled: July 31, 2015Date of Patent: April 3, 2018Assignees: Toyota Jidosha Kabushiki Kaisha, Kyoto UniversityInventors: Hirofumi Nakamoto, Zempachi Ogumi, Takeshi Abe
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Patent number: 9905328Abstract: A resin composition used as a material of an insulating layer of a printed wiring board including the insulating layer and a conductor layer formed on a surface of the insulating layer by plating, the resin composition including: an epoxy compound; a cyanate compound; a maleimide compound; an inorganic filler; and an imidazole silane, wherein the maleimide compound includes a predetermined maleimide compound, a content of the maleimide compound is 25% by mass or less based on 100% by mass of a total content of the epoxy compound, the cyanate compound, and the maleimide compound, and the imidazole silane includes a compound represented by the formula (3).Type: GrantFiled: June 2, 2014Date of Patent: February 27, 2018Assignee: MITSUBISHI GAS CHEMICAL COMPANY, INC.Inventors: Keiichi Hasebe, Naoki Kashima, Takenori Takiguchi, Takaaki Ogashiwa
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Patent number: 9586886Abstract: Fatty acids are produced through transacylation. An organic nitrogen-containing compound is reacted with alkyl sultone to generate a white solid of a zwitterionic compound. After being purified and dried, the white solid is powdered to be reacted with a Bronsted strong acid for obtaining a clear viscous water-based acidic ionic liquid (IL) as a catalyst used used to effectively process transacylation between oil and acetic acid (HOAc) for fabricating fatty acid (FFA) and glycerol triacetate (GTA). Therein, unsaturated fatty acid is simultaneously processed through addition acetoxylation to obtain stabilized acetoxy fatty acid (AFFA). After, HOAc is recycled through vacuuming. Then, the product and the IL are stratified. The product at upper layer is taken out. The IL at lower layer can be recycled for processing transacylation and addition acetoxylation repeatedly. Therein, fatty acids including the stabilized AFFA are obtained from the product after taking out GTA through vacuum distillation.Type: GrantFiled: April 20, 2016Date of Patent: March 7, 2017Assignee: CPC CORPORATION, TAIWANInventors: Jung-Chung Wu, Ming-Yu Huang, Jann-Chen Lin, Yih-Ping Wang
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Patent number: 9518068Abstract: The present invention relates to compounds containing hydrido-tricyano-borate anions, their preparation and their use, in particular as part of electrolyte formulations for electrochemical or optoelectronic devices.Type: GrantFiled: May 23, 2012Date of Patent: December 13, 2016Assignee: MERCK PATENT GMBHInventors: Nikolai (Mykola) Ignatyev, Michael Schulte, Kentaro Kawata, Tomohisa Goto, Eduard Bernhardt, Vera Bernhardt-Pitchougina, Helge Willner
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Patent number: 9260397Abstract: The present invention relates to salts comprising novel aryl-alkyl-substituted imidazolium and triazolium cations and arbitrary anions. The invention further relates to methods for the chemical conversion and separation of substances, comprising the salts according to the invention as solvents, solvent additives, or extraction means, and to the use of the salts according to the invention, for example as solvents or solvent additives in chemical reactions, as extracting agents for the separation of substances, or for storing hydrogen.Type: GrantFiled: January 30, 2009Date of Patent: February 16, 2016Assignee: TECHNISCHE UNIVERSITAET DRESDENInventors: Thomas Strassner, Sebastian Ahrens
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Patent number: 9233990Abstract: Organoaminosilanes, such as without limitation di-iso-propylaminosilane (DIPAS), are precursors for the deposition of silicon containing films such as silicon-oxide and silicon-nitride films. Described herein are methods to make organoaminosilane compounds, or other compounds such as organoaminodisilanes and organoaminocarbosilanes, via the catalytic hydrosilylation of an imine by a silicon source comprising a hydridosilane.Type: GrantFiled: February 18, 2015Date of Patent: January 12, 2016Assignee: Air Products and Chemicals, Inc.Inventors: Manchao Xiao, Matthew R. MacDonald, Richard Ho, Xinjian Lei
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Patent number: 9209409Abstract: A naphthobisthiadiazole derivative is represented by Formula 1. In Formula 1, Z is selected from a hydrogen atom, a boronic acid group, a boronic acid ester group, a trifluoroborate salt group and a triolborate salt group, and at least one Z is a boronic acid group, a boronic acid ester group, a trifluoroborate salt group or a triolborate salt group. The naphthobisthiadiazole derivative is an organoboron compound, and can be converted to various compounds by a Suzuki-Miyaura coupling reaction; thus, is applicable as a precursor of complex compounds. Using the naphthobisthiadiazole derivative, research, development, and practical applications of low molecular weight compounds and high-molecular compounds useful for various organic semiconductor materials and the like can be ensured.Type: GrantFiled: February 27, 2013Date of Patent: December 8, 2015Assignees: National University of Corporation Hiroshima University, Sankyo Kasei Co., Ltd.Inventors: Kazuo Takimiya, Itaru Osaka, Kazuaki Kawashima
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Patent number: 9040710Abstract: The present disclosure relates to a compound comprising an aryloxy-phthalocyanine compound of Group IV metals, a method for preparing aryloxy-phthalocyanine compound of Group IV metals and an article of manufacture made therefrom.Type: GrantFiled: March 5, 2014Date of Patent: May 26, 2015Assignee: Saudi Basic Industries CorporationInventors: Timothy P. Bender, Benoit H. Lessard, Ahmed Abdelrahman, Amit Tevtia
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Publication number: 20150137666Abstract: A reactive ionic liquid to be used as an ionic component that is contained in an ion-containing layer in a transducer arranged in contact with a high-resistance layer as a dielectric layer of the transducer, and is restrained from migrating from the ion-containing layer to the high-resistance layer on application of a voltage is provided. The reactive ionic liquid comprises an ion pair that consists of an anion and a cation. (a) The cation (a1) is an imidazolium or quaternary ammonium cation, and (a2) comprises a reactive group that consists of an alkoxysilyl or phosphonate group. (b) The anion (b1) is a sulfonate, sulfonylimide, or nitrobenzoate anion.Type: ApplicationFiled: December 17, 2014Publication date: May 21, 2015Applicants: SUMITOMO RIKO COMPANY LIMITED, KYUSHU UNIVERSITYInventors: Shigeaki TAKAMATSU, Yota KOKUBO, Kazunobu HASHIMOTO, Hitoshi YOSHIKAWA, Atsushi TAKAHARA, Ryousuke MATSUNO, Hideyuki OTSUKA
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Publication number: 20150141646Abstract: In certain aspects, compounds and uses thereof are provided. In certain aspects, compound-conjugates and uses thereof are provided.Type: ApplicationFiled: May 14, 2013Publication date: May 21, 2015Applicant: Concortis Biosystems, Corp., a wholly owned subsidary of Sorrento Therapeutics, Inc,Inventors: Zhenwei Miao, Yufeng Hong, Tong Zhu
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Patent number: 9029377Abstract: Cyclohexyl sulfonamide compounds which are platelet-activating factor (PAF) receptor antagonists. Said compounds may be useful, for example, for the treatment of atherosclerosis or other PAF-mediated disorders, including inflammatory, cardiovascular, and immune disorders.Type: GrantFiled: June 28, 2010Date of Patent: May 12, 2015Assignee: Merck Sharp & Dohme Corp.Inventors: Anthony Ogawa, Feroze Ujjainwalla, Lin Chu, Bing Li, Lan Wei, Jinyou Xu, Hyun Ok, Aaron Lackner, Ihor Kopka
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Publication number: 20150119364Abstract: This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.Type: ApplicationFiled: November 10, 2014Publication date: April 30, 2015Inventors: Stephen J. BAKER, Tsutomu Akama, Michael Richard Kevin Alley, Stephen J. Benkovic, Michael DiPierro, Vincent S. Hernandez, Karin M. Hold, Isaac Kennedy, Igor Likhotvorik, Weimin Mao, Kirk Maples, Jacob J. Plattner, Fernando Rock, Virginia Sanders, Aaron M. Stemphoski, George Petros Yiannikouros, Siead Zegar, Yong-Kang Zhang, Huchen Zhou
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Publication number: 20150112081Abstract: A naphthobisthiadiazole derivative is represented by Formula 1. In Formula 1, Z is selected from a hydrogen atom, a boronic acid group, a boronic acid ester group, a trifluoroborate salt group and a triolborate salt group, and at least one Z is a boronic acid group, a boronic acid ester group, a trifluoroborate salt group or a triolborate salt group. The naphthobisthiadiazole derivative is an organoboron compound, and can be converted to various compounds by a Suzuki-Miyaura coupling reaction; thus, is applicable as a precursor of complex compounds. Using the naphthobisthiadiazole derivative, research, development, and practical applications of low molecular weight compounds and high-molecular compounds useful for various organic semiconductor materials and the like can be ensured.Type: ApplicationFiled: February 27, 2013Publication date: April 23, 2015Inventors: Kazuo Takimiya, Itaru Osaka, Kazuaki Kawashima
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Patent number: 8999956Abstract: The present invention relates to fungicidal N-[(het)arylalkyl)]pyrazolecarboxamide or thiocarboxamide and their heterosubstituted analogs, their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.Type: GrantFiled: June 1, 2011Date of Patent: April 7, 2015Assignee: Bayer Intellectual Property GmbHInventors: Jurgen Benting, Pierre-Yves Coqueron, Pierre Cristau, Peter Dahmen, Philippe Desbordes, Stephanie Gary, Jorg Greul, Hiroyuki Hadano, Ruth Meissner, Ulrike Wachendorff-Neumann
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Patent number: 8999734Abstract: Disclosed herein are mono-functional silylating compounds that may exhibit enhanced silylating capabilities. Also disclosed are method of synthesizing and using these compounds. Finally methods to determine effective silylation are also disclosed.Type: GrantFiled: March 10, 2010Date of Patent: April 7, 2015Assignee: American Air Liquide, Inc.Inventors: James J. F. McAndrew, Curtis Anderson, Christian Dussarrat
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Publication number: 20150094462Abstract: A novel method of simultaneously protecting two functions which are same or different, namely hydroxyl, amine, or thiol ones, particularly in sugars, polyalcohols, nucleosides, nucleotides, peptides, and nucleic acids during an organic synthesis, and to novel compounds for implementing this method, as well as to the method of obtaining these compounds. Method of simultaneously protecting two hydroxyl, amine, or thiol functions according to the invention by carrying out a protecting reaction between a compound having at least two free hydroxyl, amine, or thiol groups, and the disilane of formula 1, where R stands for Cl or Br, or I, or a substituent of formula 2, where X1, X2, X3, X4 are the same or different.Type: ApplicationFiled: April 23, 2013Publication date: April 2, 2015Inventors: Wojciech Tadeusz Markiewicz, Marcin Krzysztof Chmielewski, Sylwia Maria Musial, Hieronim Franciszek Maciejewski, Grzegorz Hreczycho
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Publication number: 20150093655Abstract: There is provided an ionic compound having attached thereto a silyloxy group. There is also provided methods of making this ionic compound as well as electrolytes, electrochemical cells and capacitors comprising this ionic compound.Type: ApplicationFiled: April 5, 2013Publication date: April 2, 2015Inventors: Matjaz Kozelj, Abdelbast Guerfi, Julie Trottier, Karim Zaghib
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Publication number: 20150094470Abstract: Compounds and method of preparation of Si—X and Ge—X compounds (X?N, P, As and Sb) via dehydrogenative coupling between the corresponding unsubstituted silanes and amines (including ammonia) or phosphines catalyzed by metallic catalysts is described. This new approach is based on the catalytic dehydrogenative coupling of a Si—H and a X—H moiety to form a Si—X containing compound and hydrogen gas (X?N, P, As and Sb). The process can be catalyzed by transition metal heterogenous catalysts such as Ru(0) on carbon, Pd(0) on MgO) as well as transition metal organometallic complexes that act as homogeneous catalysts. The —Si—X products produced by dehydrogenative coupling are inherently halogen free. Said compounds can be useful for the deposition of thin films by chemical vapor deposition or atomic layer deposition of Si-containing films.Type: ApplicationFiled: September 19, 2014Publication date: April 2, 2015Inventors: Antonio Sanchez, Gennadily Itov, Peng Zhang, Matthew Damien Stephens
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Publication number: 20150094469Abstract: A borate moiety-contained linker and a bio-sensing element containing the same are disclosed. The borate moiety-contained linker can be used to modify a sensing molecule and connect the sensing molecule to a substrate to form the bio-sensing element.Type: ApplicationFiled: December 4, 2014Publication date: April 2, 2015Inventors: Yaw-Kuen LI, Mo-Yuan SHEN, Yu-Ju PIEN
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Publication number: 20150090963Abstract: An organic compound represented by Formula 1 is disclosed. An organic light-emitting device including the organic compound is also disclosed.Type: ApplicationFiled: February 25, 2014Publication date: April 2, 2015Applicant: SAMSUNG DISPLAY CO., LTD.Inventors: Young-Kook Kim, Kwang-Hyun Kim, Eun-Young Lee
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Patent number: 8987466Abstract: The invention provides a silicon-containing bianthracene derivative, a production process and use thereof, and an organic electroluminescent device. The invention belongs to the technical field of organic electroluminescence, and can give a blue light-emitting material being able to form a dense film. The silicon-containing bianthracene derivative has a molecular structure of the following general formula, wherein R group represents an aryl group having a carbon atom number of 6-14, an aromatic heterocyclic group having a carbon atom number of 8-18, a fused-ring aromatic group having a carbon atom number of 9-15, a fluorenyl group, or a triarylamino group. The silicon-containing bianthracene derivative mentioned in the invention can be used in an organic electroluminescent device.Type: GrantFiled: January 27, 2014Date of Patent: March 24, 2015Assignees: BOE Technology Group Co., Ltd., JiLin OLED Material Tech. Co., Ltd.Inventors: Yinan Liang, Xiaoyu Ma, Hui Wang, Wenyu Ma
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Publication number: 20150080337Abstract: The present invention relates to fungicidal N-cycloalkyl-N-[(trisubstitutedsilylphenyl)methylene]carboxamide derivatives and their thiocarbonyl derivatives, their process of preparation and intermediate compounds for their preparation, their use as fungicides, particularly in the form of fungicidal compositions and methods for the control of phytopathogenic fungi of plants using these compounds or their compositions.Type: ApplicationFiled: April 18, 2013Publication date: March 19, 2015Inventors: Pierre Cristau, Philippe Desbordes, Mazen Es-Sayed, Marie-Claire Grosjean-Cournoyer, Helene Lachaise, Philippe Rinolfi, Jan-Peter Schmidt, Tomoki Tsuchyia, Jean-Pierre Vors
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Publication number: 20150072942Abstract: Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.Type: ApplicationFiled: April 8, 2014Publication date: March 12, 2015Applicant: Millennium Pharmaceuticals, Inc.Inventors: Julian Adams, Yu-Ting Ma, Ross L. Stein, Matthew Baevsky, Louis Grenier, Louis Plamondon
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Patent number: 8975316Abstract: Modified fillers are described which have adsorbed and/or attached chemical groups, such as a triazole and/or pyrazole thereon. Other modified fillers are also described. Elastomeric compositions containing the modified filler are further described, as well as methods to improve hysteresis and/or abrasion resistance in elastomeric compositions using the modified fillers of the present invention.Type: GrantFiled: February 22, 2013Date of Patent: March 10, 2015Assignee: Cabot CorporationInventors: James A. Belmont, Vijay R. Tirumala
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Publication number: 20150065724Abstract: The present invention is directed to novel synthetic methods for preparing a compound of Structural Formula (I): wherein R is —H or a hydroxyl protecting group. Also included are synthetic intermediates described herein.Type: ApplicationFiled: September 3, 2014Publication date: March 5, 2015Applicant: AbbVie Inc.Inventors: Yi-Yin Ku, Yu-Ming Pu, Hao Yang, Alan Christesen
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Publication number: 20150057247Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of degenerative diseases and disorders.Type: ApplicationFiled: October 29, 2014Publication date: February 26, 2015Inventors: Craig C. Beeson, Christopher C. Lindsey, Yuri K. Peterson, Baerbel Rohrer
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Publication number: 20150057246Abstract: The present invention relates to novel Silyl-Containing Heterocyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, B, C, D and R2 are as defined herein. The present invention also relates to compositions comprising at least one Silyl-Containing Heterocyclic Compound, and methods of using the Silyl-Containing Heterocyclic Compounds for treating or preventing HCV infection in a patient.Type: ApplicationFiled: September 11, 2012Publication date: February 26, 2015Inventors: Michael P. Dwyer, Kartik M. Keertikar, Qingbei Zeng, Robert D. Mazzola, JR., John P. Caldwell, Haiqun Tang, Anilkumar Gopinadhan Nair, Bandarpalle B. Shankar, Stuart B. Rosenblum, Joseph A. Kozlowski
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Patent number: 8962858Abstract: Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme.Type: GrantFiled: June 26, 2014Date of Patent: February 24, 2015Assignee: Eisai R&D Management Co., Ltd.Inventors: Branko Mitasev, Dae-Shik Kim, Huiming Zhang, Christopher N. Farthing
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Publication number: 20150051171Abstract: The present invention provides a compound having an excellent efficacy for controlling pests. A tetrazolinone compound of a formula (1): [wherein R1 represents an C6-C16 aryl group, an C1-C12 alkyl group, or a C3-C12 cycloalkyl group, etc., which each optionally be substituted; R2, R3, R4 and R5 represent independently of each other a hydrogen atom, a halogen atom or an C1-C3 alkyl group, etc.; R6 represents an C1-C6 alkyl group, a C3-C6 cycloalkyl group, a halogen atom, a C1-C6 haloalkyl group, an C2-C6 alkenyl group, an C1-C6 alkoxy group, or a C1-C6 haloalkoxy group, etc.; R7, R8 and R9 represent independently of each other a hydrogen atom, a halogen atom, or an C1-C4 alkyl group, etc.; X represents an oxygen atom or a sulfur atom; and R10 represents an C1-C6 alkyl group, etc.] shows an excellent controlling efficacy on pests.Type: ApplicationFiled: April 26, 2013Publication date: February 19, 2015Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Yuya Yoshimoto, Sadayuki Arimori, Yuichi Matsuzaki
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Patent number: 8957049Abstract: The present invention provides compounds, and pharmaceutically acceptable compositions thereof, encompassed by any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof. The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof.Type: GrantFiled: October 8, 2010Date of Patent: February 17, 2015Assignee: Infinity Pharmaceuticals, Inc.Inventors: Mark L. Behnke, Alfredo C. Castro, Catherine A. Evans, Louis Grenier, Michael J. Grogan, Tao Liu, Daniel A. Snyder, Thomas T. Tibbitts
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Patent number: 8940906Abstract: The present invention relates to a nonlinear fluorescent molecule that generates a nonlinear fluorescence reaction by incidence of excitation light. This nonlinear fluorescence molecule includes donors and, and an acceptor that is coupled to the donors and. As the donor is excited by the incidence of the excitation light, electric charge moves from the donor to the acceptor. Then, the donor and the acceptor form a charge separated state. In a state in which the charge separated state is maintained, the donor fluoresces when transiting from an excited state to a ground state.Type: GrantFiled: June 21, 2010Date of Patent: January 27, 2015Assignee: Osaka UniversityInventors: Katsumasa Fujita, Shin Mizukami, Kazuya Kikuchi, Satoshi Kawata, Shogo Kawano
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Patent number: 8937183Abstract: The present invention provides compounds useful for detection of hydrogen peroxide and methods of using same.Type: GrantFiled: July 21, 2014Date of Patent: January 20, 2015Assignee: Promega CorporationInventors: Dieter Klaubert, John Shultz, James Unch, Michael P. Valley, Hui Wang, Wenhui Zhou
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Patent number: 8933441Abstract: An organic electronic device may include an organic semiconductor compound represented by the following Chemical Formula 1 or Chemical Formula 2. Each substituent of the above Chemical Formulas 1 and 2 may be the same as described in the detailed description.Type: GrantFiled: January 8, 2013Date of Patent: January 13, 2015Assignee: Samsung Electronics Co., Ltd.Inventors: Jong Won Chung, Bang Lin Lee, Jeong Il Park, Yong Wan Jin
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Patent number: 8933239Abstract: A bis(aryl)acetal has the formula wherein Y1 and Y2 are each independently chloro, bromo, iodo, mesylate, tosylate, triflate, or Bx, provided that Y1 and Y2 are not both selected from chloro, bromo, and iodo; each occurrence of Bx is independently a boron-containing functional group bonded to Ar1 or Ar2 via a boron atom; Ar1 and Ar2 are each independently unsubstituted or substituted C6-18 arylene, or unsubstituted or substituted C3-18 heteroarylene; provided that Ar1 and Ar2 are not covalently linked to each other to form a ring structure that includes —Ar1—O—C—O—Ar2—; and R1 and R2 are each independently hydrogen, unsubstituted or substituted C1-18 linear or branched alkyl, unsubstituted or substituted C3-20 cycloalkyl, unsubstituted or substituted C6-18 aryl, or unsubstituted or substituted C3-20 heteroaryl. The bis(aryl)acetal is useful as a monomer for oligoacetal and polyacetal synthesis via Suzuki polycondensation.Type: GrantFiled: July 16, 2013Date of Patent: January 13, 2015Assignee: Dow Global Technologies LLCInventors: Matthias S. Ober, Duane R. Romer, John B. Etienne, Pulikkottil J. Thomas
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Patent number: 8921576Abstract: The present invention provides a novel compound represented by a general formula (1) as shown below, which has a glucokinase-activating action in the liver and pancreatic ?-cells and which is useful as an agent for preventing and/or treating diseases caused by hyperglycemia, such as diabetes. A spiroindoline compound represented by the general formula (1), or a salt thereof, or a solvate of the compound or the salt: [wherein ring A represents a nitrogen-containing 5-10 membered heteroaryl group; R1 and R2, which are the same or different, each represent a hydrogen atom, a halogen atom, a halo C1-6 alkyl group, a C6-10 aryl group, a cyano group, a C1-6 alkyl group optionally having a substituent, a C2-6 alkenyl group optionally having a substituent, etc.; R3 represents a hydrogen atom, a C1-6 alkyl group optionally having a substituent, etc.; and R4 represents a hydrogen atom, a halogen atom, a C1-6 alkyl group optionally having a substituent, etc.Type: GrantFiled: October 18, 2012Date of Patent: December 30, 2014Assignee: Kowa Company, Ltd.Inventors: Takahisa Ogamino, Yukiyoshi Yamazaki, Shin Tanikawa, Ayumu Okuda, Tomoaki Fukuda, Okihisa Tokuda, Yoshiharu Miyake, Shinsuke Itoh, Hiroyuki Ishiwata
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Publication number: 20140378416Abstract: The present invention relates to novel Silyl-Containing Heterocyclic Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, C, D, E, F and L are as defined herein. The present invention also relates to compositions comprising at least one Silyl-Containing Heterocyclic Compound, and methods of using the Silyl-Containing Heterocyclic Compounds for treating or preventing HCV infection in a patient.Type: ApplicationFiled: September 11, 2012Publication date: December 25, 2014Inventors: Michael P. Dwyer, Kartik M. Keertikar, Qingbei Zeng, Robert D. Mazzola, JR., Wensheng Yu, Haiqun Tang, Seong Heon Kim, Ling Tong, Stuart B. Rosenblum, Joseph A. Kozlowski, Anilkumar Gopinadhan Nair