Chalcogen Bonded Directly To The 2- And 5- Positions Of The Thiadiazole Ring Patents (Class 548/142)
  • Patent number: 10316005
    Abstract: The present invention relates to a process for the preparation of bis(dimercaptothiadiazole) (or bis-DMTD), more particularly of 5,5?-dithiobis(1,3,4-thiadiazole-2-thiol), said process being carried out in a single reactor and making possible a preparation with improved yields which is more respectful of the environment.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: June 11, 2019
    Assignee: MLPC INTERNATIONAL
    Inventors: Carole Coucharriere, Thierry Aubert, Dominique Bonhomme, Jean-Yves Ehlinger
  • Patent number: 8906835
    Abstract: An extreme pressure additive composition for use in grease contains alkaline earth metal derivatives of 2,5-dimercapto-1,3,4-thiadiazole (DMTD) complexed to alkylene glycol fluids and or PAG fluids. In addition, additives for extreme pressure and antiwear contain a complex of alkali and/or alkaline earth metal derivatives of DMTD with alkylene glycol fluids and or PAG fluids, in combination with an organophosphorus compound.
    Type: Grant
    Filed: May 8, 2012
    Date of Patent: December 9, 2014
    Assignee: Vanderbilt Chemicals, LLC
    Inventors: Ronald J. Tepper, Gaston A. Aguilar
  • Publication number: 20140301975
    Abstract: Methods of treating blood disorders are described.
    Type: Application
    Filed: June 20, 2014
    Publication date: October 9, 2014
    Inventor: Susan P. Perrine
  • Patent number: 8765088
    Abstract: The degradation of an absorbent solution comprising organic compounds having a amine function in aqueous solution is substantially reduced in the presence of a small amount of thiadiazole-derived degradation inhibiting agents defined by the general formula as follows: The absorbent solution is used to deacidize a gaseous effluent.
    Type: Grant
    Filed: June 23, 2009
    Date of Patent: July 1, 2014
    Assignee: IFP Energies nouvelles
    Inventors: Pierre-Louis Carrette, Bruno Delfort
  • Publication number: 20140065387
    Abstract: The present invention relates to a dispersion comprising metallic, metal oxide or metal precursor nanoparticles and a polymeric dispersant, the dispersant comprising an anchor group with affinity for the metallic, metal oxide or metal precursor nanoparticles that is chemically bonded to a polymeric backbone characterized in that the dispersant has a 95 wt. % decomposition at a temperature below 300° C. as measured by Thermal Gravimetric Analysis. It further relates to metallic fluids or inks prepared from the dispersion and to the preparation of the dispersion and the metallic fluid or inks.
    Type: Application
    Filed: December 19, 2011
    Publication date: March 6, 2014
    Applicant: AGFA-GEVAERT NV
    Inventors: Xavier Andre, Dirk Bollen, Johan Loccufier
  • Patent number: 8480926
    Abstract: Disclosed is a visible light-transmissive liquid-crystalline compound having good hole and electron-transport characteristics and useful as an organic semiconductor material. The compound is represented by a formula (1): wherein R independently represents hydrogen, or alkyl having from 1 to 24 carbon atoms, and any —CH2— in the alkyl may be replaced by —O—, —S—, —CO— or —SiH2—, any —(CH2)2— may be replaced by —CH?CH— or —C?C—, and any hydrogen may be replaced by halogen; Ar represents naphthylene, anthrylene, phenanthrylene, or phenylene; and every hydrogen in phenylene is replaced by halogen, and any hydrogen in naphthylene, anthrylene and phenanthrylene may be replaced by halogen.
    Type: Grant
    Filed: July 4, 2011
    Date of Patent: July 9, 2013
    Assignee: JNC Corporation
    Inventors: Yasuyuki Sasada, Tetsuharu Miwa
  • Publication number: 20120289443
    Abstract: An extreme pressure additive composition for use in grease contains alkaline earth metal derivatives of 2,5-dimercapto-1,3,4-thiadiazole (DMTD) complexed to alkylene glycol fluids and or PAG fluids. In addition, additives for extreme pressure and antiwear contain a complex of alkali and/or alkaline earth metal derivatives of DMTD with alkylene glycol fluids and or PAG fluids, in combination with an organophosphorus compound.
    Type: Application
    Filed: May 8, 2012
    Publication date: November 15, 2012
    Applicant: R.T. VANDERBILT COMPANY, INC.
    Inventors: Ronald J. TEPPER, Gaston A. AGUILAR
  • Publication number: 20110319455
    Abstract: A method of treating or preventing fungal infection, which includes identifying a plant or animal having a fungal infection and administering an effective amount of an anti-fungal composition to the plant or animal to reduce the fungal infection. In a preferred form of the present invention, the antifungal composition is compound 13 or 33 and is combined with an azole compound, such as fluconazole.
    Type: Application
    Filed: April 19, 2011
    Publication date: December 29, 2011
    Inventors: Bruce Steven Klein, Brad Mark Tebbets
  • Publication number: 20110004001
    Abstract: The present invention relates to a process for the preparation of bis(dimercaptothiadiazole) (or bis-DMTD), more particularly of 5,5?-dithiobis(1,3,4-thiadiazole-2-thiol), said process being carried out in a single reactor and making possible a preparation with improved yields which is more respectful of the environment.
    Type: Application
    Filed: July 1, 2010
    Publication date: January 6, 2011
    Applicant: MLPC INTERNATIONAL
    Inventors: Carole COUCHARRIERE, Thierry AUBERT, Dominique BONHOMME, Jean-Yves EHLINGER
  • Patent number: 7750088
    Abstract: The instant invention is an improved cure system composition and a method for curing chlorinated elastomer compositions. The cure system composition includes a polymercapto crosslinking agent, an inorganic base, and a quaternary ammonium salt. The quaternary ammonium salt has a formula selected from the group consisting of wherein R1 is an alkyl or aryl group containing between 4 and 12 carbon atoms; wherein R2 and R3 are independently alkyl or aryl groups containing between 1 and 8 carbon atoms; wherein the total number of carbon atoms on R2 and R3 are between 3 and 9; wherein R4 and R5 are methyl groups, and R6 is an alkyl group containing between 2 and 8 carbon atoms; and wherein X is an anion.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: July 6, 2010
    Assignee: Dow Global Technologies
    Inventors: Raymond L. Laakso, Jr., Gary R. Marchand
  • Patent number: 7612149
    Abstract: The instant invention is an improved cure system composition and a method for curing chlorinated elastomer compositions. The cure system composition includes a polymercapto crosslinking agent, an inorganic base, and a quaternary ammonium salt. The quaternary ammonium salt has a formula selected from the group consisting of wherein R1 is an alkyl or aryl group containing between 4 and 12 carbon atoms; wherein R2 and R3 are independently alkyl or aryl groups containing between 1 and 8 carbon atoms; wherein the total number of carbon atoms on R2 and R3 are between 3 and 9; wherein R4 and R5 are methyl groups, and R6 is an alkyl group containing between 2 and 8 carbon atoms; and wherein X is an anion.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: November 3, 2009
    Assignee: Dow Global Technologies Inc.
    Inventors: Raymond L. Laakso, Jr., Gary R. Marchand
  • Publication number: 20090091234
    Abstract: A salt molten at room temperature that does not contain any organic solvent, excelling in stability; and a display device that is improved in the durability in high-temperature environment by virtue of the use thereof. There is provided a salt molten at room temperature characterized by being composed of a silver salt and any of compounds of the following general formula (I) or general formula (II).
    Type: Application
    Filed: April 6, 2006
    Publication date: April 9, 2009
    Applicant: KONICA MINOLTA HOLDINGS, INC.
    Inventor: Noriyuki Kokeguchi
  • Patent number: 7511149
    Abstract: Insecticidal sulfoximines are produced efficiently and in high yield by the oxidation of the corresponding sulfilimine with ruthenium tetraoxide or an alkali metal permanganate.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: March 31, 2009
    Assignee: Dow AgroSciences LLC
    Inventors: Kim E. Arndt, Douglas C. Bland, David E. Podhorez, James R. McConnell
  • Publication number: 20080242860
    Abstract: The present invention relates to a silver halide color photographic light-sensitive material wherein at least one of light-sensitive silver halide emulsion layers includes a silver halide emulsion having a silver chloride content of at least 95 mol % and a silver iodide content of 0.05 mol % to 0.75 mol % and/or a silver bromide content of 0.05 mol % to 4.00 mol % and further at least one compound represented by the following formula (I): X-(L)n-Y ??Formula (I) wherein X represents a group adsorptive to a silver halide, L represents a divalent connecting group comprising one of an atom and an atomic group including at least one of a carbon atom, a nitrogen atom, a sulfur atom and an oxygen atom, Y denotes a reducible group and n denotes an integer of 0 or 1.
    Type: Application
    Filed: June 3, 2008
    Publication date: October 2, 2008
    Applicant: FUJIFILM CORPORATION
    Inventors: Atsushi Matsunaga, Tadashi Inaba, Shinichi Ichikawa
  • Patent number: 7261988
    Abstract: An improved organophotoreceptor comprises an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising: (a) a charge transport material having the formula where X comprises a linking group; R1 and R1? comprise, each independently, H, an alkyl group, an alkenyl group, an alkynyl group, an aromatic group, or a heterocyclic group; and R2, R3, R2?, and R3? comprise, each independently, an arylamine group; and (b) a charge generating compound. Corresponding electrophotographic apparatuses, imaging methods, and methods of forming the charge transport material are described.
    Type: Grant
    Filed: April 27, 2004
    Date of Patent: August 28, 2007
    Assignee: Samsung Electronics Co. Ltd
    Inventors: Zbigniew Tokarski, Nusrallah Jubran, Vytautas Getautis, Maryte Daskeviciene, Ingrida Paulauskaite, Robertas Maldzius, Jonas Sidaravicius
  • Patent number: 7232929
    Abstract: The invention relates to new 2,2,3,3-tetramethylcyclopropane carboxamide derivative compounds, pharmaceutical compositions thereof and uses thereof for treating psychotic disorders, neurodegenerative diseases, epilepsy and pain.
    Type: Grant
    Filed: February 15, 2004
    Date of Patent: June 19, 2007
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Meir Bialer, Boris Yagen, Eyal Sobol, Dan Kaufmann
  • Patent number: 7208509
    Abstract: This invention relates to novel heterocyclic compounds of formula I wherein R1—R4, X1 and X2 are as defined in the summary and pharmaceutically acceptable salts and solvates thereof, methods to inhibit or modulate Human Immunodeficiency Virus (HIV) reverse transcriptase with compounds of formula I, pharmaceutical compositions containing of formula I admixed with at least one solvent, carrier or excipient and processes to prepare compounds of formula I.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: April 24, 2007
    Assignee: Roche Palo Alto LLC
    Inventors: James Patrick Dunn, Steven Swallow, Zachary Kevin Sweeney
  • Patent number: 7189482
    Abstract: Improved organophotoreceptor comprises an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising: (a) a charge transport compound having the formula where R1 and R2 are, independently, hydrogen, an alkyl group, an alkaryl group or an aryl group; X is an aromatic group; Y is an (N,N-disubstituted)arylamine; Z is (CH2)m group where m is an integer between 0 and 30 where one or more of the methylene groups is optionally replaced by O, S, C?O, O?C—O, O?C—NR3, sulfoxide, sulfate, phosphate, an aryl group, urethane, urea, NR4 group, CHR5 group, or CR6R7 group where R3, R4, R5, R6, and R7 are, independently, H, hydroxyl, thiol, an amine group, an alkyl group, an alkaryl group, a heterocyclic group, or an aryl group, and E is a bond, O, S, C?O, NR8, CR9R10 group, a hetrocyclic group, or an aromatic group where R8, R9, and R10 are, independently, H, an alkyl group, an alkaryl group, or an aryl group; and (b) a charg
    Type: Grant
    Filed: September 16, 2003
    Date of Patent: March 13, 2007
    Assignee: Samsung Electronics Co., Ltd
    Inventors: Zbigniew Tokarski, Nusrallah Jubran, Vytautas Getautis, Maryte Daskeviciene, Ingrida Paulauskaite, Robertas Maldzius, Jonas Sidaravicius
  • Patent number: 6908937
    Abstract: The present invention relates to novel heterocyclic fluoroalkenyl thioethers of the formula (I) in which X represents hydrogen, halogen or alkyl, m represents integers from 3 to 10, n represents 0, 1 or 2, Het represents the groups where R1 represents hydrogen; mercapto; optionally halogen-substituted alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl or alkenyl; optionally substituted aryl; or optionally substituted heterocyclyl, Y represents oxygen or sulphur, and R2 represents hydrogen, alkyl or optionally substituted aryl, and to processes for their preparation and to their use as pesticides.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: June 21, 2005
    Assignee: Bayer Cropscience AG
    Inventors: Udo Kraatz, Bernd Gallenkamp, Albrecht Marhold, Peter Wolfrum, Wolfram Andersch, Christoph Erdelen, Andreas Turberg, Olaf Hansen, Achim Harder
  • Patent number: 6852716
    Abstract: The invention provides compounds of Formula I: These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful in pharmaceuticals to treat diseases or conditions in which ?7 is known to be involved.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: February 8, 2005
    Assignee: Pfizer Inc
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Jason K. Myers, Vincent E. Groppi, Jr.
  • Patent number: 6620771
    Abstract: 2,5-dimercapto-1,3,4-thiadiazole dimer-poly(ether)glycol reaction products and adducts useful as extreme pressure additives. Lubricating compositions (e.g., greases) containing reaction products and adducts exhibit improved Timken Load properties.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: September 16, 2003
    Assignee: R. T. Vanderbilt Company, Inc.
    Inventors: Thomas J. Karol, Ronald J. Tepper
  • Patent number: 6569876
    Abstract: The present invention is directed to novel inhibitors and methods for inhibiting serine elastases. These compounds and methods achieve a novel approach to enzyme inhibition; namely, balanced inhibition of a plurality of serine elastases. Balanced inhibition of a plurality of elastases offers a novel approach to therapeutic treatment of diseases that involve abnormal activities of a plurality of elastases resulting in pathological changes such as occur in inflammatory and vascular conditions. These pathological changes are not limited to the breakdown of elastin but may include the processing of other proteins by serine elastases which in turn results in adverse effects. The opportunity of targeting a plurality of enzymes using single inhibitor offers therapeutic advantages over administering multiple therapeutic against where each agent has a single specificity for an individual target enzyme.
    Type: Grant
    Filed: June 19, 2000
    Date of Patent: May 27, 2003
    Inventor: John C. Cheronis
  • Patent number: 6562816
    Abstract: The invention provides compounds of Formula I: compounds of the Formula I: wherein R1, R2, R4, R6, X, and W are defined herein. These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful in pharmaceuticals used to treat diseases or conditions in which &agr;7 is known to be involved.
    Type: Grant
    Filed: August 14, 2002
    Date of Patent: May 13, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Donn G. Wishka, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, David W. Piotrowski, Jeffrey W. Corbett, Alice L. Bodnar, Vincent E. Groppi, Jr.
  • Patent number: 6489484
    Abstract: Thiadiazole-poly(ether)glycol reaction products and adducts useful as extreme pressure additives. Lubricating compositions (e.g., greases) containing the reaction products and adducts exhibit improved Timken Load properties.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: December 3, 2002
    Assignee: R. T. Vanderbilt Company, Inc.
    Inventors: Thomas J. Karol, Ronald J. Tepper
  • Patent number: 6437169
    Abstract: 1. A 1-naphthol compound represented by formula (I) below: wherein A represents the moiety of a compound having an acidic proton the pKa of a corresponding protonated form (AH) of which is 0 to 14, R1 represents an aliphatic group, aryl group, or heterocyclic group, R2 represents a substituent, n represents an integer of 0 to 5, X represents a hydrogen atom, halogen atom, R11—, R11O—, R11S—, R11OCOO—, R12COO—, R12(R13)NCOO—, R12CON(R13)—, —NO, —NO2, or —N═N—R11, wherein R11 represents an aliphatic group, aryl group, or heterocyclic group, and each of R12 and R13 independently represents a hydrogen atom, aliphatic group, aryl group, or heterocyclic group, and Y represents an oxygen atom or sulfur atom.
    Type: Grant
    Filed: June 19, 2000
    Date of Patent: August 20, 2002
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Takayuki Ito, Koji Takaku
  • Publication number: 20020058594
    Abstract: 2,5-dimercapto-1,3,4-thiadiazole dimer-poly(ether)glycol reaction products and adducts useful as extreme pressure additives. Lubricating compositions (e.g., greases) containing reaction products and adducts exhibit improved Timken Load properties.
    Type: Application
    Filed: November 14, 2001
    Publication date: May 16, 2002
    Applicant: R.T. Vanderbilt Company, Inc.
    Inventors: Thomas J. Karol, Ronald J. Tepper
  • Patent number: 6365557
    Abstract: 2,5-dimercapto-1,3,4-thiadiazole dimer-poly(ether)glycol reaction products and adducts useful as extreme pressure additives. Lubricating compositions (e.g., greases) containing reaction products and adducts exhibit improved Timken Load properties.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: April 2, 2002
    Assignee: R.T. Vanderbilt Company, Inc.
    Inventors: Thomas J. Karol, Ronald J. Tepper
  • Patent number: 6362138
    Abstract: This invention relates to compounds which are suitable as ash-free antiwear additives and antioxidants, to lubricant compositions comprising said compounds as well as to their use. are particularly preferred. In the preferred compounds I′, R2 is isooctyloxycarbonylmethyl, R3 is isooctyloxycarbonylmethylthiomethyl and R4 is hydrogen; or R2 is tert-nonyl and R3 is tert-nonylthiomethyl and R4 is hydrogen; or R2 is isooctyloxycarbonylmethyl, R3 is hydrogen and R4 is isooctyloxycarbonylmethylthiomethyl; or R2 is tert-nonyl, R3 is hydrogen and R4 I is tert-nonylthiomethyl.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: March 26, 2002
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Hugo Camenzind, Samuel Evans, Alfred Dratva, Peter Hänggi
  • Patent number: 6362137
    Abstract: This invention relates to a cost effective process for preparing a corrosion inhibitor/metal passivator additive for lubricant, grease and fuel applications from waste refinery streams, comprising reacting 2,5-dimercapto-1,3,4-thiadiazole either in powder form or in solution form in polar organic solvent, with disulphide oil obtained from Merox extraction/caustic wash of the refinery streams, in the presence or absence of redox agent.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: March 26, 2002
    Assignee: Indian Oil Corporation
    Inventors: Akhilesh Bhatnagar, Deepak Kumar Tuli, Rakesh Sarin, Ajay Arora, Pankaj Kumar Mandal
  • Patent number: 6340539
    Abstract: This invention is directed to 2,5-dimercapto-1,3,4-thiadiazole dilithium salt and its dihydrate and methods of their manufacture, and a secondary lithium battery and positive electrode-active material comprising the same.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: January 22, 2002
    Assignee: Toyo Kasei Kogyo Company Limited
    Inventors: Satoshi Yamaguchi, Satoshi Nakagawa, Sunao Mitsui, Susumu Ohno
  • Patent number: 6265351
    Abstract: The invention relates to phenylpyrazoles having general formula (I): The compounds having formula (I) have a high herbicidal activity and are used for controlling weeds in the agronomic field.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: July 24, 2001
    Assignee: Isagro Ricerca S.r.L.
    Inventors: Piero La Porta, Franco Bettarini, Giovanni Meazza, Gregorio Valea, Ernesto Signorini, Domenico Portoso
  • Patent number: 6255259
    Abstract: Suitable lubricant additives are the compounds of formulae wherein the substituents and groups have the following preferred meanings: R1=H; R2=methyl or tert-butyl; R3=tert-butyl; s=0, 1 or 2; R4=—A—[(C6H2)(methyl or tert-butyl)(OH)(tert-butyl)]; A=—CH2CH2O—(C═O)—CH2CH2— or —CH2CH(CH3)—O—(C═O)—CH2CH2—.
    Type: Grant
    Filed: February 11, 2000
    Date of Patent: July 3, 2001
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Hugo Camenzind, Alfred Dratva, Peter Hänggi
  • Patent number: 6184383
    Abstract: There is disclosed a method of producing acetals, which comprises reacting a compound of formula (I), at least one compound selected from a group consisting of a compound of formula (II), paraformaldehyde, and trioxane; and a compound of formula (III), to synthesize an acetal of formula (IV), wherein the reaction is carried out in the presence of an oxidizing agent and an acid:  wherein R1 is an alkyl group etc., R2 is an alkyl or aryl group, R3 and R4 each independently are a hydrogen atom, an alkyl group or an aryl group, X1 and X2 each are a group of nonmetal atoms necessary to form a 5- or 6-membered N-containing heteroring, and M is a hydrogen atom or a cation. This method can give acetal compounds with good efficiency and a high yield.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: February 6, 2001
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Atsuo Kondoh, Fumio Iwamoto
  • Patent number: 6150307
    Abstract: This invention relates to compounds which are suitable as ash-free antiwear additives and antioxidants, to lubricant compositions comprising said compounds as well as to their use. Compounds of formulae ##STR1## are particularly preferred. In the preferred compounds I',R.sub.2 is isooctyloxycarbonylmethyl, R.sub.3 is isooctyloxycarbonylmethylthiomethyl and R.sub.4 is hydrogen; orR.sub.2 is tert-nonyl and R.sub.3 is tert-nonylthiomethyl and R.sub.4 is hydrogen; orR.sub.2 is isooctyloxycarbonylmethyl, R.sub.3 is hydrogen and R.sub.4 is isooctyloxycarbonylmethylthiomethyl; orR.sub.2 is tert-nonyl, R.sub.3 is hydrogen and R.sub.4 I is tert-nonylthiomethyl.In the preferred compounds II',R.sub.2 and R.sub.2 ' are isooctyloxycarbonylmethyl, R.sub.3 and R.sub.3 ' are isooctyloxycarbonylmethylthiomethyl and R.sub.4 and R.sub.4 ' are hydrogen; orR.sub.2 and R.sub.2 ' are tert-nonyl, R.sub.3 and R.sub.3 ' are tert-nonylthiomethyl and R.sub.4 and R.sub.4 ' are hydrogen; orR.sub.2 and R.sub.
    Type: Grant
    Filed: August 3, 1998
    Date of Patent: November 21, 2000
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Hugo Camenzind, Samuel Evans, Alfred Dratva, Peter Hanggi
  • Patent number: 6031108
    Abstract: The present invention provides a process for making thiadiazole sulfones. In particular, the present process is used to make 2-(methylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole using catalytic oxidation in the presence of a suitable oxidizing agent. The catalyst system used for the oxidation reaction is a mixture of glacial acetic acid and a tungsten catalyst. The tungsten catalyst is preferably selected from the group consisting of sodium tungstate, potassium tunstate, and tungstic acid.
    Type: Grant
    Filed: September 16, 1998
    Date of Patent: February 29, 2000
    Assignee: Bayer Corporation
    Inventors: Vidyanatha A. Prasad, Klaus Jelich, Joe J. Hanson
  • Patent number: 5889025
    Abstract: Novel antidiabetic compounds, their tautomeric forms, their derivatives, their steroisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutical acceptable compositions containing them: Methods for preparing the antidiabetic compounds and their uses.
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: March 30, 1999
    Assignees: Reddy's Research Foundation, Reddy-Cheminor, Inc.
    Inventors: Vidya Bhushan Lohray, Braj Bhushan Lohray, Sekar Reddy Alla, Rajagopalan Ramanujam, Ranjan Chakrabarti
  • Patent number: 5849925
    Abstract: Disclosed are novel compounds prepared by reacting two moles of 2,5-dimercapto-1,3,4-thiadiazole and one mole of a hydrocarbon compound selected from terpenes, aryl compounds and aliphatic compounds which may be substituted by oxygen or oxygen containing groups. The hydrocarbon compound forms a bivalent radical linking together the two 2,5-dimercapto-1,3,4-thiadiazoles. The compounds are effective extreme pressure agents when incorporated into lubricating compositions.
    Type: Grant
    Filed: December 13, 1996
    Date of Patent: December 15, 1998
    Assignee: R. T. Vanderbilt Co.
    Inventors: Thomas J. Karol, Ronald J. Tepper
  • Patent number: 5783704
    Abstract: Compounds of formu (I) wherein n and Z are as defined in claim 1, and, where appropriate, tautomers thereof, in each case in free form, or in salt form, can be used as agrochemical active ingredients and can be prepared in a manner known per se.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: July 21, 1998
    Assignee: Novartis Corporation
    Inventors: Henry Szczepanski, Haukur Kristinsson, Peter Maienfisch, Josef Ehrenfreund
  • Patent number: 5686397
    Abstract: A composition of matter is disclosed having the structure: ##STR1## wherein R and R.sup.1 are independently a member selected from the group consisting of alkyl, cycloalkyl, aryl, aralkyl, and alkaryl; R.sup.2 is an alkylene moiety; R.sup.3 is hydrogen, alkyl, alkenyl, aryl, alkaryl, aralkyl, or 2-hydroxyalkyl; X is sulfur; and y is 0 or 1. Lubricants and lubricant additives comprising the composition are also disclosed. The lubricants are preferably lubricating oils.
    Type: Grant
    Filed: February 3, 1997
    Date of Patent: November 11, 1997
    Assignee: Uniroyal Chemical Company, Inc.
    Inventors: John R. Baranski, Cyril A. Migdal
  • Patent number: 5622922
    Abstract: A homogenous product is formed by heating at a temperature in the range of from 50.degree. to 150.degree. C. a mixture of a benzotriazole and a 2,5-dihydrocarbyldithio-1,3,4-thiadiazole.
    Type: Grant
    Filed: December 27, 1995
    Date of Patent: April 22, 1997
    Assignee: Exxon Chemical Patents Inc.
    Inventors: Dean B. Clarke, Dale R. Carroll
  • Patent number: 5602181
    Abstract: Naphthyl ethers of the general formula I ##STR1## where the index and the substituents have the meanings defined in the specification.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: February 11, 1997
    Assignee: BASF Aktiengesellschaft
    Inventors: Wassilios Grammenos, Reinhard Kirstgen, Hartmann K onig, Klaus Oberdorf, Hubert Sauter, Gisela Lorenz, Eberhard Ammermann
  • Patent number: 5597785
    Abstract: Disclosed the novel compounds prepared by reacting 2,5-dimercapto-1,3,4,-thiadiazole with maleic anhydride and N-polyethylene amine-substituted succinimide. The compounds are dispersants or detergents, antiwear agents and antioxidants when incorporated into lubricating compositions.
    Type: Grant
    Filed: June 26, 1995
    Date of Patent: January 28, 1997
    Assignee: R. T. Vanderbilt Company, Inc.
    Inventor: Thomas J. Karol
  • Patent number: 5576443
    Abstract: Disclosed is a novel near-infrared absorbing dye of formula: ##STR1## wherein X.sup.1, X.sup.2 independently represents --CR.sup.8 R.sup.9 --, --S--, --Se--, --NR.sup.10 --, --CH.dbd.CH-- or --O--;n is an integer of 2 or 3;R.sup.1 and R.sup.2 independently represent alkyl of 1 to 10 carbons or substituted alkyl of 1 to 10 carbons;R.sup.3 represents a ring chosen from a set consisting of aryl, substituted aryl, and a heterocyclic ring of a type present in photographic emulsions;R.sup.4, R.sup.5, R.sup.6 and R.sup.7 independently represent hydrogen, alkyl of 1-10 carbons, substituted alkyl of 1-10 carbons, R.sup.4 and R.sup.5 taken together or R.sup.6 and R.sup.7 taken together can represent atoms necessary to form a 5 or 6-membered aliphatic ring, an aromatic six-membered ring, an aromatic 10-membered ring, a substituted aromatic six-member ring or a substituted aromatic 10-member ring;R.sup.8, R.sup.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: November 19, 1996
    Assignee: Sterling Diagnostic Imaging, Inc.
    Inventors: Dietrich M. Fabricius, Gregory C. Weed
  • Patent number: 5573999
    Abstract: .beta.-Substituted cinnamic acid derivatives of the formula 1, ##STR1## where R.sup.1 is alkyl, chlorine or bromine, --X-- is --O--, --S--, ##STR2## m is 0 or 1, --Y is --OR.sup.4, --O--N.dbd.CR.sup.5 R.sup.6, --NR.sup.7 R.sup.8, --N(OR.sup.9)R.sup.10 or --SR.sup.11, where the above-mentioned substituents R.sup.2 to R.sup.11 are alkyl, and R.sup.2, and R.sup.3 and R.sup.5 to R.sup.11 can also be hydrogen,Z is halogen, nitro, cyano, alkyl, cycloalkyl, aralkyl, aryloxyalkyl, arylthioalkyl, hetarylalkyl, hetaryloxyalkyl, hetarylthioalkyl, alkenyl, aralkenyl, aryloxyalkenyl, arylthioalkenyl, hetarylalkenyl, hetaryloxyalkenyl, hetarylthioalkenyl, alkynyl, arylalkynyl, hetarylalkynyl, aryl, hetaryl, arylazo, acylamino, --OR.sup.12, --SR.sup.13, --SOR.sup.14, --SO.sub.2 R.sup.15, --COOR.sup.16, --CONR.sup.17 R.sup.18, --COR.sup.19, --CR.sup.20 .dbd.NR.sup.21, --N.dbd.CR.sup.22, R.sup.23, --CR.sup.24 .dbd.N--OR.sup.25, --CR.sup.25 R.sup.26 --O--, N.dbd.CR.sup.27 R.sup.28, --CH.sub.2 --OCOR.sup.39 or --NR.sup.37 R.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: November 12, 1996
    Assignee: BASF Aktiengesellschaft
    Inventors: Hubert Sauter, Herbert Bayer, Klaus Oberdorf, Horst Wingert, Wolfgang von Deyn, Wassilios Grammenos, Hartmann Koenig, Harald Rang, Franz Roehl, Gisela Lorenz, Eberhard Ammermann
  • Patent number: 5538520
    Abstract: Polyalkylene amine coupled heterocyclic compounds are effective multifunctional additives, providing cleanliness to fuels and lubricants as well as anti-wear, friction-modifying, thermal and oxidative stabilizing properties. The beneficial effects of the product of the instant invention apparently result from an internal synergism between the polyalkylene amine groups and the heterocyclic groups.
    Type: Grant
    Filed: March 25, 1994
    Date of Patent: July 23, 1996
    Assignee: Mobil Oil Corporation
    Inventors: Noyes L. Avery, Joan C. Axelrod, James T. Carey, John Hiebert, Andrew G. Horodysky
  • Patent number: 5538652
    Abstract: Combinations of dimercaptothiadiazole-mercaptan coupled derivatives with amines have been found to be effective load-carrying additives for lubricants and fuels.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: July 23, 1996
    Assignee: Mobil Oil Corporation
    Inventors: Liehpao O. Farng, Arjun K. Goyal
  • Patent number: 5512190
    Abstract: The present invention provides a lubricating oil additive which provides anti-wear properties to a lubricating oil. The additive is the reaction product of 2,5-dimercapto-1,3,4-thiadiazole and a mixture of unsaturated mono-, di-, and tri-glycerides. The present invention also provides a lubricating oil additive with anti-wear properties produced by reacting a mixture of unsaturated mono-, di-, and tri-glycerides with diethanolamine to provide an intermediate reaction product and reacting the intermediate reaction product with 2,5-dimercapto-1,3,4-thiadiazole.
    Type: Grant
    Filed: August 22, 1994
    Date of Patent: April 30, 1996
    Assignee: Texaco Inc.
    Inventors: Gregory P. Anderson, Julian H. Dancy, Doris Love, Jayne M. Lucas
  • Patent number: 5482966
    Abstract: The invention concerns oxime derivatives of the formula I ##STR1## wherein R.sup.4 includes hydrogen, carboxy, carbamoyl, amino, cyano, trifluoromethyl, (1-4C)alkylamino, di-(1-4C)alkylamino and (1-4C)alkyl;R.sup.5 includes hydrogen, (1-4C)alkyl, (3-4C)alkenyl, (3-4C)alkynyl, (2-5C)alkanoyl, halogeno-(2-4C)alkyl and hydroxy-(2-4C)alkyl;Ar.sup.1 is phenylene or a heteroaryl diradical;A.sup.1 is a direct link to X.sup.1, or A.sup.1 is (1-4C)alkylene;X.sup.1 is oxy, thio, sulphinyl or sulphonyl;Ar.sup.2 is phenylene or a heteroaryl diradical;R.sup.1 is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; andR.sup.2 and R.sup.3 together form a group of the formula --A.sup.2 --X.sup.2 --A.sup.3 -- which together with the carbon atom to which A.sup.2 and A.sup.3 are attached define a ring having 5 or 6 ring atoms, wherein each of A.sup.2 and A.sup.3 is (1-3C)alkylene and X.sup.
    Type: Grant
    Filed: June 13, 1994
    Date of Patent: January 9, 1996
    Assignees: Zeneca Limited, Zeneca Pharma S.A.
    Inventors: Thomas G. C. Bird, Patrick Ple
  • Patent number: 5453433
    Abstract: Compounds of the formula; ##STR1## wherein: Thi is thiadiazolyl or substituted thiadiazolyl;Y is alkylene bridge of 3-9 carbon atoms;R.sub.1 and R.sub.2 are each independently chosen from hydrogen, halo, alkyl, alkenyl, amino, alkylthio, hydroxy, hydroxyalkyl, alkoxyalkyl, alkylthioalkyl, alkylsulfinyl alkyl, alkylsulfonylalkyl, alkoxy, nitro, carboxy, alkoxycarbonyl, dialkylaminoalkyl, alkylaminoalkyl, aminoalkyl, difluoromethyl, trifluoromethyl, or cyano;R.sub.3 is alkoxycarbonyl, phenyl, alkyltetrazolyl, or heterocyclyl; or a pharmaceutically acceptable salt thereof are effective antipicornaviral agents.
    Type: Grant
    Filed: May 13, 1994
    Date of Patent: September 26, 1995
    Assignee: Sterling Winthrop Inc.
    Inventors: David J. Aldous, Thomas R. Bailey, Guy D. Diana, Theodore J. Nitz
  • Patent number: 5440042
    Abstract: Disclosed is a novel near-infrared absorbing dye of formula: ##STR1## wherein X.sup.1, X.sup.2 independently represents --CR.sup.8 R.sup.9 --, --S--, --Se--, --NR.sup.10 --, --CH.dbd.CH-- or --O--;n is an integer of 2 or 3;R.sup.1 and R.sup.2 independently represent alkyl of 1 to 10 carbons or substituted alkyl of 1 to 10 carbons;R.sup.3 represents a ring chosen from the set consisting of aryl, substituted aryl, and heterocyclic containing 5 or 6 carbons in the ring;R.sup.4, R.sup.5, R.sup.6 and R.sup.7 independently represent hydrogen, alkyl of 1-10 carbons, substituted alkyl of 1-10 carbons, R.sup.4 and R.sup.5 taken together or R.sup.6 and R.sup.7 taken together may represent the atoms necessary to form a 5 or 6-membered aliphatic ring, an aromatic six-membered ring, an aromatic 10-membered ring, a substituted aromatic six-member ring or a substituted aromatic 10-member ring;R.sup.8, R.sup.
    Type: Grant
    Filed: May 26, 1993
    Date of Patent: August 8, 1995
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Dietrich M. Fabricius, Gregory C. Weed