Having -c(=x)-, Wherein X Is Chalcogen, Bonded Directly To The Diazole Ring Patents (Class 548/328.1)
  • Methods of modulating PPAR gamma-type receptors
    Patent number: 8022079
    Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
    Type: Grant
    Filed: September 18, 2009
    Date of Patent: September 20, 2011
    Assignee: Galderma Research & Development
    Inventors: Laurence Clary, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel
  • Compounds that modulate PPAR?-type receptors and cosmetic/pharmaceutical compositions comprising said compounds
    Patent number: 7968560
    Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: June 28, 2011
    Assignee: Galderma Research & Development
    Inventors: Laurence Clary, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel
  • Compounds that modulate PPAR? type receptors and cosmetic/pharmaceutical compositions comprised thereof
    Patent number: 7625914
    Abstract: Novel compounds having the general formula (I) below: are useful in a wide variety of applications in human or veterinary medicine (in dermatology, and also in the fields of cardiovascular diseases, immune diseases and/or diseases associated with lipid metabolism), or, alternatively are formulated into cosmetic compositions.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: December 1, 2009
    Assignee: Galderma Research & Development
    Inventors: Laurence Clary, Etienne Thoreau, Michel Rivier, Jerome Aubert, Laurent Chantalat, Johannes Voegel
  • Sulfonamides having antiangiogenic and anticancer activity
    Publication number: 20040167128
    Abstract: Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.
    Type: Application
    Filed: October 8, 2003
    Publication date: August 26, 2004
    Inventors: Kenneth M. Comess, Scott A. Erickson, Jack Henkin, Douglas M. Kalvin, Megumi Kawai, Ki H. Kim, Nwe Y. BaMaung, Chang Hoon Park, George S. Sheppard, Anil Vasudevan, Jieyi Wang, David M. Barnes, Steve D. Fidanze, Lawrence Kolaczkowski, Robert A. Mantei, David C. Park, William J. Sanders, Jason S. Tedrow, Gary T. Wang
  • 1,4-Benzofused urea compounds useful in treating cytokine mediated diseases
    Publication number: 20030232865
    Abstract: Disclosed are 1,4-disubstituted benzo-fused urea compounds of formula (I): 1
    Type: Application
    Filed: February 19, 2003
    Publication date: December 18, 2003
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Pier Francesco Cirillo, Abdelhakim Hammach, John Robinson Regan
  • Aromatic and heteroaromatic acid halides for synthesizing polyamides
    Publication number: 20030105279
    Abstract: The present invention is directed to protected amino acid halide monomers and oligomers, and to their use in the efficient sythesis of polyamides. The present invention is further directed to the use of &agr;-haloenamine reagents, which may optionally be immobilized, for the preparation of the amino acid halides.
    Type: Application
    Filed: August 30, 2002
    Publication date: June 5, 2003
    Applicant: Pharmacia Corporation
    Inventor: Dennis P. Phillion
  • Synthesis of temozolomide and analogs
    Publication number: 20020095036
    Abstract: This invention relates to a novel process for the synthesis of Temozolomide, an antitumor compound, and analogs, and to intermediates useful in this novel process.
    Type: Application
    Filed: January 16, 2002
    Publication date: July 18, 2002
    Applicant: Schering Corporation
    Inventors: Shen-Chun Kuo, Janet L. Mas, Donald Hou