The Chalcogen Is Sulfur Patents (Class 548/330.5)
  • Association of fluconazole-tinidazole for the treatment of vaginal infections, its composition, preparation process and usage
    Patent number: 8309103
    Abstract: The present invention refers to a treatment for mixed infectious diseases in the human reproductive system, wherein an association of compounds containing fluconazole and either tinidazole or secnidazole is used, the same being associated in doses lower to those commonly used therapeutically. The combination has proven to be highly efficacious and shown a good degree of tolerance.
    Type: Grant
    Filed: January 22, 2004
    Date of Patent: November 13, 2012
    Assignee: Alparis, S.A. DE C.V.
    Inventors: Luisa Hernandez-Ramirez, Angelica Arzola-Paniagua, Raul E. Garcia-Salgado-Lopez, Fernando Poot-Lopez
  • R-isomers of nonnucleoside inhibitors
    Patent number: 6545152
    Abstract: Novel chiral derivitaves of non-nucleoside inhibitors (NNI), particularly R-isomers of halopyridyl and thiazoyl thiourea compounds are provided as potent inhibitors of reverse transcriptase (RT), and particularly of retroviral RT, most particularly HIV RT. The stereospecific compounds and compositions of the invention inhibit replication of retrovirus, particularly human immunodeficiency virus-1 (HIV-1) and drug resistant strains.
    Type: Grant
    Filed: July 18, 2000
    Date of Patent: April 8, 2003
    Assignee: Parker Hughes Institute
    Inventors: Fatih M. Uckun, Taracad K. Venkatachalam