Chalcogen Attached Indirectly To The Diazole Ring By Acyclic Nonionic Bonding Patents (Class 548/349.1)
  • Patent number: 10849839
    Abstract: A personal care formulation comprising an active compound is operable to reduce the surface friction of hair fibres and promoting inter-fibre movement. The active compound is the reaction product of a fatty acid and a polyamine. The use of the active compound in a personal care formulation works as a friction modifier operable to reduce the surface friction of hair fibres. The invention extends to the active compound and a method of reducing hair-fibre surface friction.
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: December 1, 2020
    Assignee: Croda International Plc
    Inventors: Michael Christopher Hindley, David John Freeman, James Prodger, Sean Philip Nigel Rouse
  • Publication number: 20140051712
    Abstract: The invention describes pharmaceutical agents capable of crossing the blood brain barrier to protect against organophosphate pesticides and nerve agents or other electrophiles by reactivating inhibited cholinesterase (i.e., acetylcholinesterase and butyrylcholinesterase) and other proteins in the peripheral and central nervous system.
    Type: Application
    Filed: December 16, 2011
    Publication date: February 20, 2014
    Inventors: John R. Cashman, Jarosiaw Kalisiak
  • Publication number: 20130225469
    Abstract: Aqueous hard surface cleaner compositions derived from metathesized natural oil feedstocks are disclosed. In one aspect, the compositions comprise at least one anionic surfactant derived from a metathesis-derived C10-C17 monounsaturated acid, 5 octadecene-1,18-dioic acid, or their ester derivatives. In another aspect, aqueous hard surface cleaners comprising at least one nonionic or amphoteric surfactant derived from a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives are disclosed. The aqueous cleaners noted above rival or outperform commercial baselines in a Gardner straight-line washability test. Industrial degreasers comprising a C10 or C12 amide solvent and derived from a metathesis-derived C10-C17 monounsaturated acid are superior to commercial standards.
    Type: Application
    Filed: October 25, 2011
    Publication date: August 29, 2013
    Applicant: Stepan Company
    Inventors: Dave R Allen, Randal J Bernhardt, Aaron Brown, Ronald A. Masters, Patrick Shane Wolfe, Lena Titievsky
  • Publication number: 20110152271
    Abstract: The invention provides compositions and methods for treating nasal congestion through ophthalmic delivery. The provided compositions and methods utilize low concentrations of selective ?-2 adrenergic receptor agonists. The compositions preferably include brimonidine.
    Type: Application
    Filed: December 17, 2010
    Publication date: June 23, 2011
    Inventor: Gerald Horn
  • Publication number: 20110039109
    Abstract: Activators for heat-curing epoxy resin compositions, as well as use thereof in heat-curing epoxy resin compositions. These activators are distinguished by a good activation effect as well as good storage stability.
    Type: Application
    Filed: April 30, 2009
    Publication date: February 17, 2011
    Applicant: SIKA TECHNOLOGY AG
    Inventors: Karsten Frick, Ulrich Gerber, Juergen Finter, Andreas Kramer
  • Patent number: 7863459
    Abstract: An 'onium salt, e.g. a quaternary ammonium salt, of an anionic dye may be prepared by mixing an aqueous solution of a salt of the dye with a solution of a water-insoluble 'onium salt in an organic solvent, and separating a solution of the 'onium salt of the anionic dye in the organic solvent from the residual aqueous solution.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: January 4, 2011
    Assignee: Sun Chemical Corporation
    Inventor: Robert Lines
  • Publication number: 20100308285
    Abstract: The present invention provides (I) a method of manufacturing a triphenylmethane colorant that can suppress the sub-reactions in conversion to a sulfonamide and is industrially advantageous, (II) a colorant compound that has both excellent spectral characteristics and a high solubility relative to organic solvents or polymers as a coloring agent to be used in color filters and (III) a blue resist composition for use in a color filter that shows a high lightness and an excellent hue particularly for blue color and can be used to display an image that is excellent in terms of spectral characteristics and contrast.
    Type: Application
    Filed: August 19, 2010
    Publication date: December 9, 2010
    Applicant: CANON KABUSHIKI KAISHA
    Inventors: Yasuaki Murai, Takayuki Toyoda, Yuko Yamagishi, Takeshi Miyazaki
  • Publication number: 20100041573
    Abstract: The present invention relates to a product of reaction between a primary and/or secondary amine and one or more active ingredients. By the present invention, there is provided a release of the active component over a longer period of time than by the use of the active itself.
    Type: Application
    Filed: October 22, 2009
    Publication date: February 18, 2010
    Applicant: The Procter & Gamble Company
    Inventors: Jean-Luc Philippe Bettiol, Alfred Busch, Hugo Denutte, Christophe Laudamiel, Peter Marie Kamiel Perneel, Marie Montserrat Sanchez-Pena, Johan Smets
  • Publication number: 20090194731
    Abstract: Oxidized and maleated derivative compositions, such as chemically modified oxidized and maleated tall oil fatty acid compositions, can be prepared and used in a variety of industrial applications, including as emulsifiers, corrosion inhibitors, concrete admixtures, and in reverse flotation mining applications.
    Type: Application
    Filed: January 30, 2009
    Publication date: August 6, 2009
    Applicant: GEORGIA-PACIFIC CHEMICALS LLC
    Inventors: Phillip W. Hurd, Roger Scott Johnson, John B. Hines, Brett A. Neumann
  • Publication number: 20090143364
    Abstract: and the pharmaceutically acceptable salts and esters thereof, wherein X1, X2, X3, Y1, Y2 and R are described herein inhibit the interaction of MDM2 protein with a p53-like peptide and hence have anti proliferative activity.
    Type: Application
    Filed: February 5, 2009
    Publication date: June 4, 2009
    Inventors: Nader Fotouhi, Gregory Jay Haley, Klaus B. Simonsen, Binh Thanh Vu, Stephen Evan Webber
  • Publication number: 20080287686
    Abstract: An 'onium salt, e.g. a quaternary ammonium salt, of an anionic dye maybe prepared by mixing an aqueous solution of a salt of the dye with a solution of a water-insoluble 'onium salt in an organic solvent, and separating a solution of the 'onium salt of the anionic dye in the organic solvent from the residual aqueous solution.
    Type: Application
    Filed: December 18, 2006
    Publication date: November 20, 2008
    Applicant: Sun Chemical Corp
    Inventor: Robert Lines
  • Patent number: 7425639
    Abstract: An improved process for preparing arylethanoldiamines is described. Compounds of this type are known to be useful as agonists at a typical beta-adrenoceptors (also known as beta-3-adrenoceptors).
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: September 16, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Jason William Beames Cooke, Bobby Neal Glover, Ronnie Maxwell Lawrence, Matthew Jude Sharp, Maria Fumiko Tymoschenko
  • Patent number: 7291642
    Abstract: The present invention provides bradykinin-B1 antagonists of the formula in which A, Ar, G, Q, R1 and R4 are as defined in claim 1, their enantiomers, their diastereomers, their mixtures and their salts, in particular their physiologically acceptable salts with organic or inorganic acids or bases having useful properties, their preparation, medicaments comprising the pharmacologically effective compounds, their preparation and their use.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: November 6, 2007
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Iris Kauffmann-Hefner, Norbert Hauel, Henri Doods, Angelo Ceci, Stefan Peters
  • Patent number: 6949567
    Abstract: The invention relates to new diphenylurea having the formula (I) or a salt thereof, where Y is C?O, C?S, C?NH, (C?O)2 or SO2; and to processes for the preparation of these compounds and to their use in the treatment of protozoal diseases and to diseases where the inhibition of intracellular protein-degradation pathways is of benefit.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: September 27, 2005
    Assignee: 4SC AG
    Inventors: Andrea Aschenbrenner, Katharina Aulinger Fuchs, Matthias Dormeyer, Gabriel Garcia, Bernd Kramer, J├╝rgen Kraus, Rolf Krauss, Johan Leban, Stefano Pegoraro, Wael Saeb, Kristina Wolf
  • Patent number: 6884801
    Abstract: Compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Such compounds are useful in the treatment of Alpha-1A mediated diseases or conditions such as urinary incontinence.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: April 26, 2005
    Assignee: SmithKline Beecham Corporation
    Inventors: Eric Cleveland Bigham, Michael Joseph Bishop, David Harold Drewry, Deanna Trojan Garrison, Stephen Joseph Hodson, Frank Navas, III, Jason D. Speake
  • Patent number: 6756395
    Abstract: Compounds of the Formula: where R1-R6 are those defined herein and methods for producing the same. Also provided are pharmaceutical compositions comprising a Compound of Formula I and methods for their use as therapeutic agents.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: June 29, 2004
    Assignee: Roche Palo Alto LLC
    Inventors: Michael Patrick Dillon, Clara Jeou Jen Lin, Counde O'Yang, Xiaoming Zhang
  • Patent number: 6743817
    Abstract: Disclosed are compounds of the formula and the pharmaceutically acceptable salts thereof wherein R, Ar, A, n, R1 and R2 are defined herein. These compounds are highly selective agonists, antagonists or inverse agonists for GABAA brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAA brain receptors and are therefore useful in the diagnosis and treatment of anxiety, depression, Down Syndrome, sleep and seizure disorders, overdose with benzodiazepine drugs and for enhancement of memory. Pharmaceutical compositions, including packaged pharmaceutical compositions, are also disclosed.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: June 1, 2004
    Assignee: Neurogen Corporation
    Inventors: George Maynard, LingHong Xie, Stanislaw Rachwal
  • Patent number: 6696572
    Abstract: The present invention relates to a process for making and a method for using a corrosion inhibitor composition to reduce the corrosion rate of a metal by a fluid containing a corrosion agent. The corrosion inhibitor composition comprises at least a quaternized compound. Examples of the quaternized compound are quaternized imino imidazolines and quaternized amido imidazolines.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: February 24, 2004
    Assignee: Ondeo Nalco Energy Services, L.P.
    Inventor: George Richard Meyer
  • Patent number: 6653321
    Abstract: Methods for treating conditions associated with hyperglycemia, especially Type II diabetes, with novel naphthylsulfonic acids and related compounds. These compounds, as single stereoisomers or mixtures of stereoisomers, or their pharmaceutically acceptable salts, are useful in methods of stimulating the kinase activity of the insulin receptor, enhancing the activation of the insulin receptor by insulin, and stimulating the uptake of glucose into cells. A variety of antidiabetic compounds and pharmaceutical compositions comprising the antidiabetic compounds are also disclosed.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: November 25, 2003
    Assignee: Telik, Inc.
    Inventors: Wayne R. Spevak, Songyuan Shi, Prasad V. V. S. V. Manchem, Michael R. Kozlowski, Steven R. Schow, Robert T. Lum, Louise Robinson, Jeong Weon Park
  • Patent number: 6552061
    Abstract: Provided are an anti-inflammatory agent containing, as an active ingredient, at least one selected from amino acid derivatives represented by formula (I) wherein Ar represents an optionally substituted 2-hydroxyaryl group, n is 0 or 1, R2 represents a hydrogen atom or a side chain of an &agr;-amino acid or &bgr;-amino acid, X represents —O— or —NH—, R1 represents a hydrogen atom or a group that forms, together with R2 and an adjacent atoms, a cyclic structure of pyroglutamic acid, and R3 represents a hydrogen atom, an alkyl group having from 1 to 22 carbon atoms or an alkenyl group having from 2 to 22 carbon atoms, and salts thereof, and toiletries or skin external products containing the same. The anti-inflammatory agent of the invention inhibits expression of an inflammatory protein and activation of a gene transcription control factor that participates therein, and exhibits a good feeling upon use and a safety.
    Type: Grant
    Filed: April 2, 1999
    Date of Patent: April 22, 2003
    Assignee: Ajinomoto Co., Inc.
    Inventors: Manabu Kitazawa, Keiji Iwasaki, Eiji Shiojiri
  • Patent number: 6488868
    Abstract: The present invention relates to a process for making and a method for using a corrosion inhibitor composition to reduce the corrosion rate of a metal by a fluid containing a corrosion agent. The corrosion inhibitor composition comprises at least a quaternized compound having a substituted diethylamino moiety. Examples of the quaternized compound having a substituted diethylamino moiety are quaternized diacrylamino imidazolines.
    Type: Grant
    Filed: March 15, 1999
    Date of Patent: December 3, 2002
    Assignee: Ondeo Nalco Energy Services, L.P.
    Inventor: George Richard Meyer
  • Patent number: 6448411
    Abstract: The present invention relates to a process for making and a method for using a corrosion inhibitor composition to reduce the corrosion rate of a metal by a fluid containing a corrosion agent. The corrosion inhibitor composition comprises at least a quaternized compound. Examples of the quaternized compound are quaternized imino imidazolines and quaternized amido imidazolines.
    Type: Grant
    Filed: March 15, 1999
    Date of Patent: September 10, 2002
    Assignee: Ondeo Nalco Energy Services, L.P.
    Inventor: George Richard Meyer
  • Patent number: 6380237
    Abstract: The invention relates to novel diphenylimidazolines of the formula (I) in which Ar1, Ar2 and R are each as defined in the description, and a plurality of processes for their preparation and to their use for controlling animal pests.
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: April 30, 2002
    Assignee: Bayer Aktiengesellschaft
    Inventors: Alan Graff, Andrew Plant, Christoph Erdelen, Norbert Mencke, Andreas Turberg
  • Patent number: 6376765
    Abstract: An electrolyte composition comprising a compound represented by the following general formula (1): wherein R represents a substituent containing a —(CR1R2—CR3R4—O)n— bond (in which R1 to R4 are independently a hydrogen atom or an alkyl group, n being an integer of 2 to 20); Q represents an atomic group forming an aromatic cation having a 5- or 6-membered ring structure with a nitrogen atom, which may have a substituent; and X− represents an anion. A photoelectric conversion device comprising the electrolyte composition and a photo-electrochemical cell composed thereof are also provided.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: April 23, 2002
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Koji Wariishi, Chang-yi Qian, Michio Ono
  • Patent number: 6372918
    Abstract: The invention relates to compounds of the formula 1 R1—O—(A—O)x—(CH2)y—R2  (1) in which R1 is branched or straight-chain C4-C30-alkyl, C4-C30-alkenyl or C4-C30-alkylaryl, A is C2-C4-alkylene, x is an integer from 1 to 100, y is 1, 2, 3 or 4 and R2 is a radical selected from structures of the formulae 2 and 3 —CO—NR3R4  (2) in which one of the radicals R3 and R4 is a hydrocarbon chain which has at least one free NH or NH2 group and the other radical is hydrogen or a hydrocarbon chain which has at least one free NH or NH2 group and R5 is hydrogen or a hydrocarbon chain which has at least one free NH or NH2 group.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: April 16, 2002
    Assignee: Clariant GmbH
    Inventors: Michael Feustel, Peter Klug
  • Patent number: 6344473
    Abstract: 1,3-diazolino and 1,3-diazolidino heterocycle derivatives useful as nitric oxide synthase inhibitors.
    Type: Grant
    Filed: August 7, 2000
    Date of Patent: February 5, 2002
    Assignee: G.D. Searle & Co.
    Inventors: Donald W. Hansen, Jr., Arija A. Bergmanis, Timothy J. Hagen, E. Ann Hallinan, Steven W. Kramer, Suzanne Metz, Karen B. Peterson, Barnett S. Pitzele, Foe S. Tjoeng, Mihaly V. Toth, Mahima Trivedi, R. Keith Webber, Sofya Tsymbalov, Rolando E. Gapud
  • Patent number: 6331552
    Abstract: Substituted imidazolidine derivatives of the formula I, in which B, E, W, Y, R, R2, R3, R30, e and h have the meanings indicated in the claims. The compounds of the formula I are valuable pharmaceutical active compounds, which are suitable, for example, for the therapy of inflammatory disorders, for example of rheumatoid arthritis, or of allergic disorders. The compounds of the formula I are inhibitors of the adhesion and migration of leucocytes and/or antagonists of the adhesion receptor VLA-4 belonging to the integrins group. They are generally suitable for the therapy or prophylaxis of illnesses which are caused by an undesired extent of leucocyte adhesion and/or leucocyte migration or are associated therewith, or in which cell-cell or cell-matrix interactions which are based on interactions of VLA-4 receptors with their ligands play a part.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: December 18, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Volkmar Wehner, Hans Ulrich Stilz, Wolfgang Schmidt, Dirk Seiffge
  • Patent number: 6245520
    Abstract: Methods for introducing nucleic acids into mammalian cells are provided which use imidazolium lipids. The imidazolium lipids have the formula: wherein R1 and R2 each independently represent a C8-C24 saturated or unsaturated hydrocarbon chain, uninterrupted or interrupted by from 1 to 3 heteroatom moieties selected from —O—, —S—, —NH— and —NR—; X represents —CH2—, —O—, —S—, —NH— or —NR—; wherein R is a lower alkyl group having from 1 to 4 carbon atoms; n is an integer of from 1 to 2; and A− is an anion.
    Type: Grant
    Filed: July 25, 2000
    Date of Patent: June 12, 2001
    Assignee: Megabios Corporation
    Inventors: Jinkang Wang, Ralph Niven, Yilin Zhang, Pingzhong Huang
  • Patent number: 6200938
    Abstract: Amphoteric derivatives of aliphatic polyamines, such as diethylenetriamine or triethylenetetramine reacted with long chain fatty acids, esters or triglycerides from various natural or synthetic sources are effective in the softening/texture modification of substrates such as paper, textiles, human skin surfaces and hair tresses, as well as in applications for metal working and lubrication. The polyamines are first reacted with fatty acids, esters or triglycerides derived from various animal, vegetable or synthetic sources ranging in molecular distribution from butyric through erucic acids (e.g. milkfat, soy bean oil, rapeseed oil) to form polyamines or imidazolines; they are then further reacted with unsaturated or halogenated carboxylic acids, carboxylated epoxy compounds or acid anhydrides (e.g. acrylic acid, itaconic acid, chloroacetic acid, maleic anhydrides octadecenyl anhydride) to form the various amphoteric structures.
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: March 13, 2001
    Assignee: Mona Industries, Inc.
    Inventors: James e. Perella, Joseph A. Komor, Richard D. Katstra