The Chalcogen, X, Is In A -c(=x)x- Group, Wherein Xs Are The Same Or Diverse Chalcogens Patents (Class 548/352.1)
  • Patent number: 10479768
    Abstract: The present invention generally relates to improved processes for the preparation of amphiphilic imidazolinium compounds such as 1-[2-(9(Z)-octadecenoyloxy)ethyl]-2-(8(Z)-heptadecenyl)-3-(2-hydroxyethyl)imidazolinium chloride (DOTIM). In particular, the invention relates to processes for the synthesis of such compounds that avoid the need for toxic reagents, are more economical, and result in less waste than conventional methods. DOTIM and similar compounds can be formulated as cationic liposomes, which are useful as chemical vectors for nucleic acid delivery in gene therapy.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: November 19, 2019
    Assignee: Bayer Animal Health GmbH
    Inventors: Marco Brünjes, Mark James Ford
  • Patent number: 9040653
    Abstract: This disclosure provides methods of controlled polymerization of cyclic compounds catalyzed by carbene derivatives having a general formula as shown below, and to obtain a biodegradable polymeric material having a large molecular weight, a narrow dispersity, and no metallic impurity.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: May 26, 2015
    Assignee: NANJING UNIVERSITY OF TECHNOLOGY
    Inventors: Zhenjiang Li, Pingkai Ouyang, He Huang
  • Publication number: 20120001163
    Abstract: A photoelectric conversion element is provided which includes a photoelectrode (101) having a porous semiconductor layer (106) and a transparent electrode (107) and a counter electrode (102) disposed to face the photoelectrode (101) and in which a nitroxyl radical compound expressed by General Formula 1 is mainly enclosed between the photoelectrode (101) and the counter electrode (102). (where A in General Formula 1 represents a substituted or unsubstituted aromatic group and may contain one or more atoms of oxygen, nitrogen, sulfur, silicon, phosphorus, boron, or halogen and the aromatic group may be obtained by condensing a plurality of aromatic groups).
    Type: Application
    Filed: March 4, 2010
    Publication date: January 5, 2012
    Applicant: NEC CORPORATION
    Inventors: Kenji Kobayashi, Kentaro Nakahara, Masahiro Suguro, Shin Nakamura
  • Publication number: 20110308617
    Abstract: A photoelectric conversion element is provided which includes a semiconductor electrode (108) containing a semiconductor layer (103) and a dye, a counter electrode (109), and an electrolyte layer (104) disposed between the semiconductor electrode (108) and the counter electrode (109) and in which the dye contains a compound expressed by General Formula 1. (where A in General Formula 1 represents a substituted or unsubstituted aromatic group and may contain one or more atoms of oxygen, nitrogen, sulfur, silicon, phosphorus, boron, or halogen and the aromatic group may be obtained by condensing a plurality of aromatic groups).
    Type: Application
    Filed: March 4, 2010
    Publication date: December 22, 2011
    Applicant: NEC CORPORATION
    Inventors: Kentaro Nakahara, Kenji Kobayashi, Masahiro Suguro, Shin Nakamura
  • Patent number: 8044215
    Abstract: The disclosure provides new methods for preparing nitrogen-containing amphiphiles and their use in the preparation of liposomes and other lipid-containing carriers of pharmaceutical substances, including nucleic acids used in gene therapy.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: October 25, 2011
    Assignee: Juvaris BioTherapeutics, Inc.
    Inventors: Cheng-Sein Yu, Lee B. Bussey
  • Publication number: 20100280258
    Abstract: The disclosure provides new methods for preparing nitrogen-containing amphiphiles and their use in the preparation of liposomes and other lipid-containing carriers of pharmaceutical substances, including nucleic acids used in gene therapy.
    Type: Application
    Filed: April 29, 2009
    Publication date: November 4, 2010
    Applicant: Juvaris BioTherapeutics, Inc.
    Inventors: Cheng-Sein Yu, Lee B. Bussey
  • Publication number: 20100087656
    Abstract: The present invention relates to methods of improving the low temperature storage and performance properties of fatty acids and/or derivatives thereof, as well as compositions containing fatty acids and/or derivatives thereof having superior lower temperature storage and performance properties.
    Type: Application
    Filed: August 31, 2009
    Publication date: April 8, 2010
    Inventors: Dries Muller, Pedro Lopes, Mark Brewer, Erik Kelderman, David Broere
  • Patent number: 7504542
    Abstract: The present invention relates to the preparation of ?-hydroxy ketones of the general formula I. In particular, the invention relates to novel imidazolinium carboxylate adducts and to a novel process for using catalytic amounts of imidazolium and imidazolinium carboxylate adducts in the acyloin reaction of aldehydes to prepare hydroxy ketones of the general formula I, where R and R? are the same or different and are each H or a straight-chain or branched and optionally substituted C1-C12-alkyl radical, and R??H3CSCH2CH2, t-butyl, n-butyl, sec-butyl, n-propyl, i-propyl, an optionally heteroatom-substituted C6-C18-aryl, heteroaryl, C6-C18-arylalkyl, especially phenylmethyl, where phenyl may again be heteroatom-substituted, or heteroalkyl.
    Type: Grant
    Filed: August 10, 2007
    Date of Patent: March 17, 2009
    Assignee: Evonik Degussa GmbH
    Inventors: Ralf Jackstell, Irina Jovel, Matthias Beller, Martin Hateley, Christoph Weckbecker, Klaus Huthmacher
  • Patent number: 7485729
    Abstract: The present invention is directed to novel organometallic complexes as catalysts for the reaction of compounds with isocyanate and hydroxyl functional groups to form urethane and/or polyurethane and the process employing such catalysts. More particularly, the present invention is directed to novel complexes of zinc(II) with substituted amidines. These novel catalysts are useful for the production of urethanes and polyurethanes which are important in many industrial applications.
    Type: Grant
    Filed: July 17, 2006
    Date of Patent: February 3, 2009
    Assignee: King Industries, Inc.
    Inventors: Bing Hsieh, Ramanathan Ravichandran, Farouk Abi-Karam
  • Publication number: 20040235924
    Abstract: The present invention relates to novel heterocyclic antagonists of Formula (I) and pharmaceutical compositions comprising said antagonists of the corticotropin releasing factor receptor (“CRF receptor”) 1
    Type: Application
    Filed: February 4, 2004
    Publication date: November 25, 2004
    Inventors: Xiaojun Han, Gene M. Dubowchik, John E. Macor
  • Patent number: 6750352
    Abstract: A polymerizable molten salt monomer represented by the following general formula (I): wherein Q represents a nitrogen-containing aromatic heterocyclic atomic group which can form a cation; Y1 represents a divalent interlocking group or a bonding hand; Y2 represents a substituted or unsubstituted alkyl group; n represents an integer of from 2 to 20; m represents an integer of 2 or more; X− represents an anion; plural Y1's and plural Y2's may be the same or different, respectively, with the proviso that at least one of Y2's has a polymerizable substituent group; and a plurality of the compounds of the general formula (I) may be connected to each other at Q or Y2 to form a dimer, trimer or tetramer. Also disclosed are an electrolyte composition containing a polymer compound obtained by the polymerization of the molten salt monomer, and a cell containing the electrolyte composition.
    Type: Grant
    Filed: January 22, 2001
    Date of Patent: June 15, 2004
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Michio Ono, Chang-yi Qian
  • Publication number: 20030225288
    Abstract: Disclosed are novel compounds and a method of treating inflammatory diseases.
    Type: Application
    Filed: April 12, 2002
    Publication date: December 4, 2003
    Applicants: Millennium Pharmaceuticals, Inc., Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Etsuo Ohshima, Hiroki Sone, Osamu Kotera, Jay R. Luly, Gregory J. LaRosa
  • Publication number: 20030208082
    Abstract: This invention relates to a compound and the use of the compound of the formula 1
    Type: Application
    Filed: March 25, 2003
    Publication date: November 6, 2003
    Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
  • Patent number: 6599445
    Abstract: The present invention relates to a process for making and a method for using a corrosion inhibitor composition to reduce the corrosion rate of a metal by a fluid containing a corrosion agent. The corrosion inhibitor composition comprises at least a quaternized compound having a substituted diethylamino moiety. Examples of the quaternized compound having a substituted diethylamino moiety are quaternized diacrylamino imidazolines.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: July 29, 2003
    Assignee: Ondeo Nalco Energy Services, L.P.
    Inventor: George Richard Meyer
  • Publication number: 20030083445
    Abstract: The invention provides a method for converting a less active or slower to initiate system to a higher activity system so that at the end of a polymerization the most active species is present in the system. The invention generally relates to a process for converting a less active or slower to initiate catalyst system to a higher activity catalyst system wherein the process comprises contacting a protected N-heterocyclic carbene with a metathesis catalyst and an olefin in the presence of energy. One of the benefits of the invention is that the amount of catalyst required is less than or lowered in the presence of the protected N-heterocyclic carbene as compared to the amount of catalyst required in the absence of the protected N-heterocyclic carbene. The protected N-heterocyclic carbene can be unsaturated or saturated. In addition, the invention describes novel ruthenium initiators and methods of making the same.
    Type: Application
    Filed: May 3, 2002
    Publication date: May 1, 2003
    Inventors: Robert H. Grubbs, Jason L. Moore, John P. Morgan, Andrew Bell
  • Patent number: 6488868
    Abstract: The present invention relates to a process for making and a method for using a corrosion inhibitor composition to reduce the corrosion rate of a metal by a fluid containing a corrosion agent. The corrosion inhibitor composition comprises at least a quaternized compound having a substituted diethylamino moiety. Examples of the quaternized compound having a substituted diethylamino moiety are quaternized diacrylamino imidazolines.
    Type: Grant
    Filed: March 15, 1999
    Date of Patent: December 3, 2002
    Assignee: Ondeo Nalco Energy Services, L.P.
    Inventor: George Richard Meyer
  • Patent number: 6448411
    Abstract: The present invention relates to a process for making and a method for using a corrosion inhibitor composition to reduce the corrosion rate of a metal by a fluid containing a corrosion agent. The corrosion inhibitor composition comprises at least a quaternized compound. Examples of the quaternized compound are quaternized imino imidazolines and quaternized amido imidazolines.
    Type: Grant
    Filed: March 15, 1999
    Date of Patent: September 10, 2002
    Assignee: Ondeo Nalco Energy Services, L.P.
    Inventor: George Richard Meyer
  • Patent number: 6232496
    Abstract: Amphoacetate surfactants are made by reacting a compound of formula RCONHCH2CH2NHCH2CH2OH where R is an aliphatic radical, with formaldehyde and a cyanide of formula: R1CN, wherein R1 represents a hydrogen atom or an alkali metal, and, when R1 represents a hydrogen atom, hydrolysing the nitrile obtained with an alkali.
    Type: Grant
    Filed: November 22, 1995
    Date of Patent: May 15, 2001
    Assignee: Rhone-Poulenc Chemicals Limited
    Inventors: John F. Carr, Peter Lees, Richard Stocks-Wilson, Derek Pakenham
  • Patent number: 6222046
    Abstract: The invention has disclosed a trifluoroacetoxylation agent and a preparation process of the agent, which is safe and ease to handle, very useful in industry, and represented by the formula (1); wherein R1 to R4 are a substituted or unsubstituted, saturated or unsaturated alkyl group or a substituted or unsubstituted aryl group and can be the same or different, R1 and R2 or R3 and R4 can bond to form a ring containing a nitrogen atom or a nitrogen atom and other hetero atoms, and R1 and R3 can bond to form a ring containing a nitrogen atom or a nitrogen atom and other hetero atoms.
    Type: Grant
    Filed: August 9, 1999
    Date of Patent: April 24, 2001
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Hidetoshi Hayashi, Hiroshi Sonoda, Kenichi Goto, Kouki Fukumura, Junko Naruse, Teruyuki Nagata