The Chalcogen, X, Is In A -c(=x)x- Group, Wherein Xs Are The Same Or Diverse Chalcogens Patents (Class 548/352.1)
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Patent number: 10479768Abstract: The present invention generally relates to improved processes for the preparation of amphiphilic imidazolinium compounds such as 1-[2-(9(Z)-octadecenoyloxy)ethyl]-2-(8(Z)-heptadecenyl)-3-(2-hydroxyethyl)imidazolinium chloride (DOTIM). In particular, the invention relates to processes for the synthesis of such compounds that avoid the need for toxic reagents, are more economical, and result in less waste than conventional methods. DOTIM and similar compounds can be formulated as cationic liposomes, which are useful as chemical vectors for nucleic acid delivery in gene therapy.Type: GrantFiled: May 3, 2016Date of Patent: November 19, 2019Assignee: Bayer Animal Health GmbHInventors: Marco Brünjes, Mark James Ford
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Patent number: 9040653Abstract: This disclosure provides methods of controlled polymerization of cyclic compounds catalyzed by carbene derivatives having a general formula as shown below, and to obtain a biodegradable polymeric material having a large molecular weight, a narrow dispersity, and no metallic impurity.Type: GrantFiled: February 24, 2011Date of Patent: May 26, 2015Assignee: NANJING UNIVERSITY OF TECHNOLOGYInventors: Zhenjiang Li, Pingkai Ouyang, He Huang
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Publication number: 20120001163Abstract: A photoelectric conversion element is provided which includes a photoelectrode (101) having a porous semiconductor layer (106) and a transparent electrode (107) and a counter electrode (102) disposed to face the photoelectrode (101) and in which a nitroxyl radical compound expressed by General Formula 1 is mainly enclosed between the photoelectrode (101) and the counter electrode (102). (where A in General Formula 1 represents a substituted or unsubstituted aromatic group and may contain one or more atoms of oxygen, nitrogen, sulfur, silicon, phosphorus, boron, or halogen and the aromatic group may be obtained by condensing a plurality of aromatic groups).Type: ApplicationFiled: March 4, 2010Publication date: January 5, 2012Applicant: NEC CORPORATIONInventors: Kenji Kobayashi, Kentaro Nakahara, Masahiro Suguro, Shin Nakamura
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Publication number: 20110308617Abstract: A photoelectric conversion element is provided which includes a semiconductor electrode (108) containing a semiconductor layer (103) and a dye, a counter electrode (109), and an electrolyte layer (104) disposed between the semiconductor electrode (108) and the counter electrode (109) and in which the dye contains a compound expressed by General Formula 1. (where A in General Formula 1 represents a substituted or unsubstituted aromatic group and may contain one or more atoms of oxygen, nitrogen, sulfur, silicon, phosphorus, boron, or halogen and the aromatic group may be obtained by condensing a plurality of aromatic groups).Type: ApplicationFiled: March 4, 2010Publication date: December 22, 2011Applicant: NEC CORPORATIONInventors: Kentaro Nakahara, Kenji Kobayashi, Masahiro Suguro, Shin Nakamura
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Patent number: 8044215Abstract: The disclosure provides new methods for preparing nitrogen-containing amphiphiles and their use in the preparation of liposomes and other lipid-containing carriers of pharmaceutical substances, including nucleic acids used in gene therapy.Type: GrantFiled: April 29, 2009Date of Patent: October 25, 2011Assignee: Juvaris BioTherapeutics, Inc.Inventors: Cheng-Sein Yu, Lee B. Bussey
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Publication number: 20100280258Abstract: The disclosure provides new methods for preparing nitrogen-containing amphiphiles and their use in the preparation of liposomes and other lipid-containing carriers of pharmaceutical substances, including nucleic acids used in gene therapy.Type: ApplicationFiled: April 29, 2009Publication date: November 4, 2010Applicant: Juvaris BioTherapeutics, Inc.Inventors: Cheng-Sein Yu, Lee B. Bussey
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Publication number: 20100087656Abstract: The present invention relates to methods of improving the low temperature storage and performance properties of fatty acids and/or derivatives thereof, as well as compositions containing fatty acids and/or derivatives thereof having superior lower temperature storage and performance properties.Type: ApplicationFiled: August 31, 2009Publication date: April 8, 2010Inventors: Dries Muller, Pedro Lopes, Mark Brewer, Erik Kelderman, David Broere
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Patent number: 7504542Abstract: The present invention relates to the preparation of ?-hydroxy ketones of the general formula I. In particular, the invention relates to novel imidazolinium carboxylate adducts and to a novel process for using catalytic amounts of imidazolium and imidazolinium carboxylate adducts in the acyloin reaction of aldehydes to prepare hydroxy ketones of the general formula I, where R and R? are the same or different and are each H or a straight-chain or branched and optionally substituted C1-C12-alkyl radical, and R??H3CSCH2CH2, t-butyl, n-butyl, sec-butyl, n-propyl, i-propyl, an optionally heteroatom-substituted C6-C18-aryl, heteroaryl, C6-C18-arylalkyl, especially phenylmethyl, where phenyl may again be heteroatom-substituted, or heteroalkyl.Type: GrantFiled: August 10, 2007Date of Patent: March 17, 2009Assignee: Evonik Degussa GmbHInventors: Ralf Jackstell, Irina Jovel, Matthias Beller, Martin Hateley, Christoph Weckbecker, Klaus Huthmacher
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Patent number: 7485729Abstract: The present invention is directed to novel organometallic complexes as catalysts for the reaction of compounds with isocyanate and hydroxyl functional groups to form urethane and/or polyurethane and the process employing such catalysts. More particularly, the present invention is directed to novel complexes of zinc(II) with substituted amidines. These novel catalysts are useful for the production of urethanes and polyurethanes which are important in many industrial applications.Type: GrantFiled: July 17, 2006Date of Patent: February 3, 2009Assignee: King Industries, Inc.Inventors: Bing Hsieh, Ramanathan Ravichandran, Farouk Abi-Karam
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Publication number: 20040235924Abstract: The present invention relates to novel heterocyclic antagonists of Formula (I) and pharmaceutical compositions comprising said antagonists of the corticotropin releasing factor receptor (“CRF receptor”) 1Type: ApplicationFiled: February 4, 2004Publication date: November 25, 2004Inventors: Xiaojun Han, Gene M. Dubowchik, John E. Macor
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Patent number: 6750352Abstract: A polymerizable molten salt monomer represented by the following general formula (I): wherein Q represents a nitrogen-containing aromatic heterocyclic atomic group which can form a cation; Y1 represents a divalent interlocking group or a bonding hand; Y2 represents a substituted or unsubstituted alkyl group; n represents an integer of from 2 to 20; m represents an integer of 2 or more; X− represents an anion; plural Y1's and plural Y2's may be the same or different, respectively, with the proviso that at least one of Y2's has a polymerizable substituent group; and a plurality of the compounds of the general formula (I) may be connected to each other at Q or Y2 to form a dimer, trimer or tetramer. Also disclosed are an electrolyte composition containing a polymer compound obtained by the polymerization of the molten salt monomer, and a cell containing the electrolyte composition.Type: GrantFiled: January 22, 2001Date of Patent: June 15, 2004Assignee: Fuji Photo Film Co., Ltd.Inventors: Michio Ono, Chang-yi Qian
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Publication number: 20030225288Abstract: Disclosed are novel compounds and a method of treating inflammatory diseases.Type: ApplicationFiled: April 12, 2002Publication date: December 4, 2003Applicants: Millennium Pharmaceuticals, Inc., Kyowa Hakko Kogyo Co., Ltd.Inventors: Etsuo Ohshima, Hiroki Sone, Osamu Kotera, Jay R. Luly, Gregory J. LaRosa
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Publication number: 20030208082Abstract: This invention relates to a compound and the use of the compound of the formula 1Type: ApplicationFiled: March 25, 2003Publication date: November 6, 2003Inventors: Vincent Mutel, Jens-Uwe Peters, Juergen Wichmann
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Patent number: 6599445Abstract: The present invention relates to a process for making and a method for using a corrosion inhibitor composition to reduce the corrosion rate of a metal by a fluid containing a corrosion agent. The corrosion inhibitor composition comprises at least a quaternized compound having a substituted diethylamino moiety. Examples of the quaternized compound having a substituted diethylamino moiety are quaternized diacrylamino imidazolines.Type: GrantFiled: July 18, 2002Date of Patent: July 29, 2003Assignee: Ondeo Nalco Energy Services, L.P.Inventor: George Richard Meyer
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Publication number: 20030083445Abstract: The invention provides a method for converting a less active or slower to initiate system to a higher activity system so that at the end of a polymerization the most active species is present in the system. The invention generally relates to a process for converting a less active or slower to initiate catalyst system to a higher activity catalyst system wherein the process comprises contacting a protected N-heterocyclic carbene with a metathesis catalyst and an olefin in the presence of energy. One of the benefits of the invention is that the amount of catalyst required is less than or lowered in the presence of the protected N-heterocyclic carbene as compared to the amount of catalyst required in the absence of the protected N-heterocyclic carbene. The protected N-heterocyclic carbene can be unsaturated or saturated. In addition, the invention describes novel ruthenium initiators and methods of making the same.Type: ApplicationFiled: May 3, 2002Publication date: May 1, 2003Inventors: Robert H. Grubbs, Jason L. Moore, John P. Morgan, Andrew Bell
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Patent number: 6488868Abstract: The present invention relates to a process for making and a method for using a corrosion inhibitor composition to reduce the corrosion rate of a metal by a fluid containing a corrosion agent. The corrosion inhibitor composition comprises at least a quaternized compound having a substituted diethylamino moiety. Examples of the quaternized compound having a substituted diethylamino moiety are quaternized diacrylamino imidazolines.Type: GrantFiled: March 15, 1999Date of Patent: December 3, 2002Assignee: Ondeo Nalco Energy Services, L.P.Inventor: George Richard Meyer
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Patent number: 6448411Abstract: The present invention relates to a process for making and a method for using a corrosion inhibitor composition to reduce the corrosion rate of a metal by a fluid containing a corrosion agent. The corrosion inhibitor composition comprises at least a quaternized compound. Examples of the quaternized compound are quaternized imino imidazolines and quaternized amido imidazolines.Type: GrantFiled: March 15, 1999Date of Patent: September 10, 2002Assignee: Ondeo Nalco Energy Services, L.P.Inventor: George Richard Meyer
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Patent number: 6232496Abstract: Amphoacetate surfactants are made by reacting a compound of formula RCONHCH2CH2NHCH2CH2OH where R is an aliphatic radical, with formaldehyde and a cyanide of formula: R1CN, wherein R1 represents a hydrogen atom or an alkali metal, and, when R1 represents a hydrogen atom, hydrolysing the nitrile obtained with an alkali.Type: GrantFiled: November 22, 1995Date of Patent: May 15, 2001Assignee: Rhone-Poulenc Chemicals LimitedInventors: John F. Carr, Peter Lees, Richard Stocks-Wilson, Derek Pakenham
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Patent number: 6222046Abstract: The invention has disclosed a trifluoroacetoxylation agent and a preparation process of the agent, which is safe and ease to handle, very useful in industry, and represented by the formula (1); wherein R1 to R4 are a substituted or unsubstituted, saturated or unsaturated alkyl group or a substituted or unsubstituted aryl group and can be the same or different, R1 and R2 or R3 and R4 can bond to form a ring containing a nitrogen atom or a nitrogen atom and other hetero atoms, and R1 and R3 can bond to form a ring containing a nitrogen atom or a nitrogen atom and other hetero atoms.Type: GrantFiled: August 9, 1999Date of Patent: April 24, 2001Assignee: Mitsui Chemicals, Inc.Inventors: Hidetoshi Hayashi, Hiroshi Sonoda, Kenichi Goto, Kouki Fukumura, Junko Naruse, Teruyuki Nagata