Plural Chalcogens Bonded Directly To Diazole Ring Carbons Patents (Class 548/366.4)
  • Publication number: 20130296455
    Abstract: Disclosed are a dye that is excellent in solubility and heat-resistance, and a novel compound that is suitable for the dye, and specifically provides a yellow dye having a maximum absorption wavelength in the region of 420 to 470 nm. Also disclosed are a colored (alkali-developable) photosensitive composition and an optical filter using the dye, and specifically provides a color filter that does not decrease luminance and thus is preferable for an image display device such as a liquid crystal display panel. Specifically, disclosed are a novel compound represented by the following general formula (1), a dye using the compound, and a colored (alkali-developable) photosensitive composition and a color filter. The content of the above-mentioned general formula (1) is as described in the description.
    Type: Application
    Filed: December 27, 2011
    Publication date: November 7, 2013
    Applicant: ADEKA CORPORATION
    Inventors: Yosuke Maeda, Masaaki Shimizu, Koichi Shigeno
  • Patent number: 8470867
    Abstract: The invention relates to compounds of formula (I) having pharmacological activity towards the sigma receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which the sigma receptor is involved.
    Type: Grant
    Filed: February 9, 2010
    Date of Patent: June 25, 2013
    Assignee: Laboratorios Del Dr. Esteve, S.A.
    Inventors: Christian Laggner, María Rosa Cuberes-Altisent, Joerg Holenz, Juana María Berrocal-Romero, Maria Montserrat Contijoch-Llobet
  • Patent number: 8440839
    Abstract: The present invention provides: dinitropyrazole derivatives of formula (I) in which: R?NO2, NH2, NF2, NHOH, OH or NHNH2 and R??H when R?NH2, NF2, NHOH, OH or NHNH2 or R??H, NH2 or a linear or branched C1-C4 alkyl group, optionally substituted by at least one hydroxy and/or one fluoro group, when R?NO2; other than 4-amino-3,5-dinitropyrazole; and also the salts of said derivatives of formula (I) in which R??H; the preparation of said derivatives and of their salts; and energetic compositions comprising at least one of said derivatives and/or at least one salt of such a derivative.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: May 14, 2013
    Assignees: Herakles, Eurenco
    Inventor: Gregoire Herve
  • Patent number: 8273784
    Abstract: The present invention provides: dinitropyrazole derivatives of formula (I) in which: R?NO2, NH2, NF2, NHOH, OH or NHNH2 and R??H when R?NH2, NF2, NHOH, OH or NHNH2 or R??H, NH2 or a linear or branched C1-C4 alkyl group, optionally substituted by at least one hydroxy and/or one fluoro group, when R?NO2; other than 4-amino-3,5-dinitropyrazole; and also the salts of said derivatives of formula (I) in which R??H; the preparation of said derivatives and of their salts; and energetic compositions comprising at least one of said derivatives and/or at least one salt of such a derivative.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: September 25, 2012
    Assignees: Herakles, Eurenco
    Inventor: Gregoire Herve
  • Publication number: 20120129833
    Abstract: The invention relates to 5?-biphenyl-substituted cyclic ketoenols for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of diabetes, obesity, hyperlipidaemia, fatty livers and of disorders of the cardiovascular system.
    Type: Application
    Filed: August 19, 2011
    Publication date: May 24, 2012
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Ningshu LIU, Kai Thede, Philip Lienau, Arne Scholz, Maher Najjar, Ulf Bomer, Knut Eis, Reiner Fischer
  • Patent number: 7981890
    Abstract: A compound of the formula (I): wherein RH represents one or more optional substituents on the fused cyclohexene ring; R1 is selected from H and halo; RN is selected from H and optionally substituted C1-10 alkyl; and RC1 and RC2 are independently selected from H, R, C(?O)OR, where R is optionally substituted C1-10 alkyl, optionally substituted C5-20 aryl or optionally substituted C3-20 heterocyclyl; RC1 and RC2 together with the carbon atom to which they are attached may form an optionally substituted spiro-fused C5-7 carbocylic or heterocyclic ring.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: July 19, 2011
    Assignee: AstraZeneca AB
    Inventors: Muhammad Hashim Javaid, Keith Allan Menear, Niall Morrison Barr Martin
  • Publication number: 20110092368
    Abstract: The present invention relates to novel 2,4,6-phenyl-substituted cyclic ketoenols of the formula (I) in which W, X, Y and CKE have the meanings given in the disclosure, to a plurality of processes for their preparation and to their use as pesticides and/or herbicides. The invention further relates to selectively herbicidal compositions containing 2,4,6-phenyl-substituted cyclic ketoenols and a compound which improves crop plant tolerance.
    Type: Application
    Filed: December 17, 2010
    Publication date: April 21, 2011
    Inventors: Reiner Fischer, Klaus Kunz, Stefan Lehr, Michael Ruther, Udo Schneider, Markus Dollinger, Mark Wilhelm Drewes, Dieter Feucht, Jörg Konze, Ulrike Wachendorff-Neumann, Guido Bojack, Thomas Auler, Martin Jeffrey Hills, Thomas Bretschneider, Olga Malsam, Christoph Erdelen, Angelika Lubos-Erdelen, Alfred Angermann, Hein Kehne, Christopher Hugh Rosinger
  • Patent number: 7872038
    Abstract: The invention relates to 1-(2,4,6-trisubstituted-phenyl)-5-amino-4-substituted-pyrazole derivatives of formula (I) or salts thereof wherein the various symbols are as defined in the description, to processes for their preparation, to compositions thereof, and to their use for the control of pests (including arthropods and helminths).
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: January 18, 2011
    Assignee: Merial Limited
    Inventors: Stefan Schnatterer, David Teh-Wei Chou, Werner Knauf, Daniela Jans, Karl Seeger
  • Publication number: 20100311593
    Abstract: The invention relates to novel compounds of the formula (I), in which W, X, Y, Z and CKE are each as defined above, to several methods and intermediates for preparation thereof and to the use thereof as pesticides and/or herbicides. The invention also relates to selective herbicidal compositions which comprise firstly haloalkylmethyleneoxyphenyl-substituted ketoenols and secondly a compound which improves crop plant compatibility. The present invention further relates to the enhancement of the action of crop protection compositions comprising especially haloalkylmethyleneoxyphenyl-substituted ketoenols, by the addition of ammonium or phosphonium salts and optionally penetration enhancers, to the corresponding compositions, to methods for production thereof and to the use thereof in crop protection as insecticides and/or acaricides and/or for preventing undesired plant growth.
    Type: Application
    Filed: March 11, 2010
    Publication date: December 9, 2010
    Applicant: Bayer Cropscience AG
    Inventors: Reiner Fischer, Thomas Bretschneider, Stefan Lehr, Eva-Maria Franken, Olga Malsam, Arnd Voerste, Ulrich Görgens, Jan Dittgen, Dieter Feucht, Isolde Häuser-Hahn, Christopher Hugh Rosinger, Alfred Angermann
  • Patent number: 7776791
    Abstract: The invention relates to novel N-heterocyclylphenyl-substituted cyclic ketoenols of the formula (I) in which CKE, W, X, Y and Z are as defined in the disclosure, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides and/or microbicides. The invention further relates to selective herbicidal compositions comprising firstly the N-heterocyclylphenyl-substituted cyclic ketoenols and secondly a compound which improves crop plant tolerance.
    Type: Grant
    Filed: June 7, 2004
    Date of Patent: August 17, 2010
    Assignee: Bayer CropScience AG
    Inventors: Reiner Fischer, Astrid Ullmann, Thomas Bretschneider, Stefan Lehr, Klaus Kunz, Jörg Konze, Olga Malsam, Mark Wilhelm Drewes, Dieter Feucht, Karl-Heinz Kuck, Ulrike Wachendorff-Neumann, Wahed Ahmed Moradi, Guido Bojack, Thomas Auler, Martin Hills, Heinz Kehne
  • Publication number: 20100010123
    Abstract: An ultraviolet absorbent, containing a compound represented by formula (1) or (2); and a polymer material containing the ultraviolet absorbent: wherein R11, R12 and R14 each independently represent a monovalent substituent; R13 represents a hydrogen atom or a substituent having a Hammett substituent constant ?p of ?0.35 or more; and n represents an integer of 0 to 4; and wherein R21 represents a substituted or unsubstituted alkyl group having 1 to 18 carbon atoms, or a substituted or unsubstituted phenyl group; R22 represents a substituted or unsubstituted alkyl group having 1 to 18 carbon atoms; R23 represents a hydrogen atom or a substituent having a Hammett substituent constant ?p of ?0.35 or more; R24 represents a monovalent substituent; and m represents an integer of 0 to 4.
    Type: Application
    Filed: July 8, 2009
    Publication date: January 14, 2010
    Inventors: Yoshihiko Fujie, Takashi Hoshimiya, Hisashi Mikoshiba
  • Patent number: 7569517
    Abstract: The invention relates to novel 4-biphenyl-substituted 4-substituted pyrazolidine-3,5-diones of the formula (I) in which A, D, G, W, X, Y and Z are as defined above, to processes and intermediates for their preparation and to their use as pesticides and/or microbicides and/or herbicides. Moreover, the invention relates to selective herbicidal compositions comprising both the 4-biphenyl-substituted 4-substituted pyrazolidine-3,5-diones and a crop plant compatibility-improving compound.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: August 4, 2009
    Assignee: Bayer CropScience AG
    Inventors: Reiner Fischer, Ernst Rudolf F. Gesing, Dieter Feucht, Karl-Heinz Kuck, Peter Lösel, Olga Malsam, Christian Arnold, Thomas Auler, Martin Jeffrey Hills, Heinz Kehne
  • Publication number: 20090163560
    Abstract: A compound having a structure and therapeutic methods, compositions, and medicaments related thereto are disclosed herein.
    Type: Application
    Filed: February 17, 2009
    Publication date: June 25, 2009
    Inventors: David W. Old, Danny T. Dinh
  • Patent number: 7517983
    Abstract: The present invention describes a process to form hydrazides from the reaction of a hydrazine and a dicarboxylic, using a Lewis acid as a main reagent of the reaction. The reaction occurs in a safe reactional environment, utilizing smooth conditions, neither involving high temperatures nor high pressures, producing the desired products with high yields, between 90-95%. The invention also describes a kit for utilization of chemiluminescent substances, comprised of two solutions.
    Type: Grant
    Filed: November 25, 2004
    Date of Patent: April 14, 2009
    Assignee: Universidade Federal Do Rio De Janeiro-UFRG
    Inventors: Cláudio Cerqueira Lopes, Rosângela Sabattini Capella Lopes, Jarí Nobrega Cardoso, Jacqueline Alves da Silva, Letícia Gomes Ferreira
  • Patent number: 7511149
    Abstract: Insecticidal sulfoximines are produced efficiently and in high yield by the oxidation of the corresponding sulfilimine with ruthenium tetraoxide or an alkali metal permanganate.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: March 31, 2009
    Assignee: Dow AgroSciences LLC
    Inventors: Kim E. Arndt, Douglas C. Bland, David E. Podhorez, James R. McConnell
  • Patent number: 7507833
    Abstract: A compound having a structure and therapeutic methods, compositions, and medicaments related thereto are disclosed herein.
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: March 24, 2009
    Assignee: Allergan, Inc.
    Inventors: David W. Old, Danny T. Dinh
  • Patent number: 7488818
    Abstract: The present invention is directed to the preparation of novel compounds useful in the treatment of hyperlipidemia, arteriosclerosis, hypercholesterolemia, and other related metabolic disorders. More specifically, the present invention is a novel process for the preparation of 1,4-diphenylazetidinone derivatives from ?-substituted amino amides which are protected in the presence of silylating agents and at least one cyclization catalyst whose structural formula is represented by one of the general formula: wherein the various R-groups are defined herein.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: February 10, 2009
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Andreas Lindenschmidt, David William Will, Gerhard Jaehne, Theodor Andreas Wollmann, Wendelin Frick, Bernd Junker, David Rigal, Guenter Billen, Heiner Jendralla
  • Patent number: 7468381
    Abstract: A method of controlling parasites in or on an animal comprising administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: December 23, 2008
    Inventors: Scot Kevin Huber, David Teh-Wei Chou, Stefan Schnatterer, Henricus Maria Martinus Bastiaans
  • Patent number: 7459414
    Abstract: Compounds of formula wherein the substituents have the meanings given in claim 1, and agronomically tolerable salts, isomers and enantiomers of those compounds, are suitable for use as herbicides.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: December 2, 2008
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Thomas Maetzke, André Stoller, Sebastian Wendeborn, Henry Szczepanski
  • Patent number: 7256298
    Abstract: The present invention provides pyrazole derivatives useful as production intermediates for isoxazoline derivatives having an excellent herbicidal effect and selectivity between crops and weeds as well as processes for producing the same.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: August 14, 2007
    Assignees: Ihara Chemical Industry Co., Ltd., Kumiai Chemical Industry Co., Ltd.
    Inventors: Masao Nakatani, Minoru Ito, Masahiro Miyazaki
  • Patent number: 7109228
    Abstract: This invention relates to pyrazole derivatives of formula (I) or pharmaceutically acceptable salts, solvates or derivatives thereof, and to processes for the preparation thereof, intermediates used in their preparation of, compositions containing them and the uses of such derivatives. The compounds of the present invention bind to the enzyme reverse transcriptase and are modulators, especially inhibitors thereof. As such, the compounds of the present invention are useful in the treatment of a variety of disorders including those in which the inhibition of reverse transcriptase is implicated. Disorders of interest include those caused by Human Immunodificiency Virus (HIV) and genetically related retroviruses, such as Acquired Immune Deficiency Syndrome (AIDS).
    Type: Grant
    Filed: April 5, 2002
    Date of Patent: September 19, 2006
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Lyn Howard Jones, Charles Eric Mowbray, David Anthony Price, Matthew Duncan Selby, Paul Anthony Stupple
  • Patent number: 7105471
    Abstract: The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) in which X represents halogen, alkyl, alkoxy, alkenyloxy, alkylthio, alkylsulphinyl, alkylsulphonyl, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro, cyano or in each case optionally substituted phenyl, phenoxy, phenylthio, phenylalkoxy or phenylalkylthio, Y represents in each case optionally substituted cycloalkyl, aryl or hetaryl, Z represents hydrogen, halogen, alkyl, alkoxy, alkenyloxy, halogenoalkyl, halogenoalkoxy, halogenoalkenyloxy, nitro or cyano, CKE represents one of the groups ?in which A, B, D, G and Q1 to Q6 are each as defined in the description, to a plurality of processes for their preparation and to their use as pesticides and herbicides.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: September 12, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Folker Lieb, Reiner Fischer, Alan Graff, Udo Schneider, Thomas Bretschneider, Christoph Erdelen, Wolfram Andersch, Mark-Wilhelm Drewes, Markus Dollinger, Ingo Wetcholowsky, Randy Allen Myers
  • Patent number: 6987104
    Abstract: N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.
    Type: Grant
    Filed: June 14, 2002
    Date of Patent: January 17, 2006
    Assignee: Vicuron Pharmaceuticals Inc.
    Inventors: Jeffrey Jacobs, Rakesh K. Jain, Jason G. Lewis, Dinesh V. Patel, Zhengyu Yuan
  • Patent number: 6894005
    Abstract: Compounds of formula wherein the substituents have the meanings given in claim 1, and agronomically tolerable salts, isomers and enantiomer of those compounds, are suitable for use as herbicides.
    Type: Grant
    Filed: September 5, 2000
    Date of Patent: May 17, 2005
    Assignee: Syngenta Crop Protection, Inc.
    Inventors: Thomas Maetzke, André Stoller, Sebastian Wendeborn, Henry Szczepanski
  • Patent number: 6852749
    Abstract: The invention provides the use of an optionally hydroxy-protected 4-hydroxyo or hydroperoxy-3,5-dioxopyrazolidine or an equivalent wherein a pyrazolidine ring attached oxygen is replaced by a sulphur, or a physiologically acceptable salt thereof, for the manufacture of a medicament for use in therapy or prophylaxis. Additionally, the invention provides a method of combating HIV infection which comprises administering to an HIV-infected patient a T-lymphocyte growth suppressing agent, preferably a pyrazolidinol, in an amount sufficient to suppress T-lymphocyte growth in said patient for a period sufficient to reduce the T-lymphocyte concentration in lymph nodes in said patient by at least 25%, said administration being repeated at intervals of at least 3 months.
    Type: Grant
    Filed: June 29, 2000
    Date of Patent: February 8, 2005
    Inventors: Enok Tjøtta, Jo Klaveness
  • Publication number: 20040198797
    Abstract: A process for the preparation of compounds of formula I 1
    Type: Application
    Filed: February 13, 2003
    Publication date: October 7, 2004
    Inventors: Thomas Maetzke, Rene Mutti, Henry Szczepanski
  • Publication number: 20040142261
    Abstract: A photosensitive layer contains an electron-transfer agent that makes use of a compound represented by the following general formula (1): 1
    Type: Application
    Filed: September 30, 2003
    Publication date: July 22, 2004
    Applicants: PERMACHEM ASIA, LTD., SHINDENGEN ELECTRIC MANUFACTURING CO., LTD., YAMANASHI ELECTRONICS CO., LTD.
    Inventors: Yasuyuki Kiuchi, Toyozoh Satoh, Hitoshi Takahashi, Tomoko Kitsunai, Hiroki Suzuki, Mitsuyo Momose
  • Patent number: 6686318
    Abstract: The invention relates to new substituted aromatic amino compounds of the general formula (I) in which R1, R2, R3, R4 and Z have the meanings given in the description, to a process for their preparation, and to their use as herbicides.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: February 3, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Roland Andree, Mark Wilhelm Drewes, Kurt Findeisen, Joachim Kluth, Karl-Heinz Linker, Klaus-Helmut Müller, Otto Schallner, Markus Dollinger
  • Publication number: 20030144504
    Abstract: The present invention relates to new compounds of the formula (I) 1
    Type: Application
    Filed: July 18, 2002
    Publication date: July 31, 2003
    Inventors: Reiner Fischer, Thomas Bretschneider, Hermann Hagemann, Folker Lieb, Michael Ruther, Arno Widdig, Peter Dahmen, Markus Dollinger, Christoph Erdelen, Hans-Joachim Santel, Ulrike Wachendorff-Neumann, Alan Graff, Wolfram Andersch
  • Patent number: 6576632
    Abstract: The present invention relates to compounds of formula I and to pharmaceutically acceptable salts, hydrates and prodrugs thereof, wherein R1, R2, R3, R4, R5, R10, R11, b, m, n, p and v are as defined herein. The invention also relates to pharmaceutical compositions containing the above compounds and methods of treating hyperproliferative disorders in mammals by administering the above compounds.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: June 10, 2003
    Assignee: Pfizer Inc
    Inventors: Steven W. Goldstein, Kelly P. Longo, James F. Blake, Mohamed M. A. Awad, Kenneth P. Raiche, Kevin W. Kramer
  • Patent number: 6551360
    Abstract: The present invention relates to a composition for dyeing keratin fibres, in particular human hair, containing, in a medium which is suitable for dyeing: as coupler, at least one compound of formula: or one of the addition salts thereof with an acid, in which: R2 denotes, in particular, hydrogen, halogen, alkoxy, aryloxy, acetylamido, etc. R1 and R3, which are independent, denote, in, particular: hydrogen, alkyl, aryl, a heterocycle, etc. it being understood that when R2 and R1 simultaneously represent a hydrogen atom, then R1 is other than a hydrogen atom, a C1-C5 alkyl radical or a phenyl radical; and at least one oxidation base.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: April 22, 2003
    Inventors: Laurent Vidal, Gérard Malle
  • Publication number: 20030073851
    Abstract: The present invention relates to novel arylphenyl-substituted cyclic ketoenols of the formula (I) 1
    Type: Application
    Filed: May 9, 2002
    Publication date: April 17, 2003
    Inventors: Folker Lieb, Reiner Fischer, Alan Graff, Udo Schneider, Thomas Bretshneider, Christoph Erdelen, Wolfram Andersch, Mark Wilhelm Drewes, Markus Dollinger, Ingo Wetcholowsky, Randy Allen Myers
  • Publication number: 20030045432
    Abstract: The present invention relates to new compounds of the formula (I) 1
    Type: Application
    Filed: December 11, 2001
    Publication date: March 6, 2003
    Inventors: Reiner Fischer, Thomas Bretschneider, Hermann Hagemann, Folker Lieb, Norbert Lui, Michael Ruther, Arno Widdig, Christoph Erdelen, Ulrike Wachendorff-Neumann, Hans-Joachim Santel, Markus Dollinger, Peter Dahmen, Norbert Mencke, Andreas Turberg
  • Patent number: 6458474
    Abstract: Disclosed is a novel methine compound, for example, which is represented by the following formula (I): wherein R1, R2, R3, R4 and R5 each represents a hydrogen atom or a substituent; X represents an oxygen atom, a sulfur atom, or N—R6; Z represents —NR7R8, or —OG; R6, R7 and R8 each represents a hydrogen atom or a substituent; G represents a hydrogen atom, a cation or a substituent; L1, L2 and L3 each represents a substituted or unsubstituted methine group; n represents 1 or 2; and W represents an electron attractive group.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: October 1, 2002
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Hisashi Okada, Terukazu Yanagi
  • Patent number: 6451790
    Abstract: Compounds of formula I wherein W is optionally substituted alkylene; Y is N or CRa; Ra is hydrogen, halogen or alkyl; R1n represents hydrogen or 1 to 4 substituents; R2 is hydrogen, nitro, cyano, halogen, alkyl, haloalkyl, alkoxy, alkylthio or alkoxycarbonyl; R3 is optionally substituted alkyl, cycloalkyl, aryl or hetaryl; A is N—OR4, CH—OR4, CH—SR4 or CHR5; R4 is alkyl or haloalkyl; R5 is halogen, alkyl or haloalkyl; methods and intermediates for their preparation. The compounds and compositions comprising them are useful for combating animal pests and harmful fungi.
    Type: Grant
    Filed: July 11, 2001
    Date of Patent: September 17, 2002
    Assignee: BASF Aktiengesellschaft
    Inventors: Markus Gewehr, Hubert Sauter, Bernd Müller, Wassilios Grammenos, Andreas Gypser, Arne Ptock, Oliver Cullmann, Jordi Tormo i Blasco, Eberhard Ammermann, Siegfried Strathmann, Gisela Lorenz, Volker Harries, Roland Götz, Thomas Grote
  • Publication number: 20020052510
    Abstract: This invention relates to novel N-linked sulfonamides of N-heterocyclic carboxylic acid and carboxylic acid isosteres, their preparation, and use for treating neurological disorders including physically damaged nerves and neurodegenerative diseases, and for treating alopecia and promoting hair growth.
    Type: Application
    Filed: December 3, 1998
    Publication date: May 2, 2002
    Inventors: GREGORY S. HAMILTON, MARK H. NORMAN, YONG-QIAN WU
  • Publication number: 20020022575
    Abstract: The present invention relates to new compounds of the formula (I) 1
    Type: Application
    Filed: April 20, 2001
    Publication date: February 21, 2002
    Inventors: Reiner Fischer, Thomas Bretschneider, Hermann Hagemann, Folker Lieb, Michael Ruther, Arno Widdig, Peter Dahmen, Markus Dollinger, Christoph Erdelen, Hans-Joachim Santel, Ulrike Wachendorff-Neumann, Alan Graff, Wolfram Andersch
  • Patent number: 6331537
    Abstract: This invention relates to novel N-heteorocyclic carboxylic acids and carboxylic acid isosteres, their preparation and use for treating neurological disorders including physically damaged nerves and neurodengenerative diseases, for treating alopecia and promoting hair growth, for treating vision disorders and/or improving vision, and for treating memory impairment and/or enhancing memory performance by administering such compounds.
    Type: Grant
    Filed: December 2, 1999
    Date of Patent: December 18, 2001
    Assignee: GPI Nil Holdings, Inc.
    Inventors: Gregory S. Hamilton, Mark H. Norman, Yong-Qian Wu
  • Patent number: 6322775
    Abstract: The present invention relates to novel cosmetic compositions, in particular for coloring the skin and/or the hair, comprising, in a cosmetically acceptable support, at least one 4,5-pyrazolinedione. The invention also relates to novel 4,5-pyrazolinediones, to processes for their preparation and to their uses in the cosmetics field.
    Type: Grant
    Filed: January 6, 1999
    Date of Patent: November 27, 2001
    Assignee: L'Oreal S.A.
    Inventors: Gérard Malle, Laurent Vidal
  • Patent number: 6180568
    Abstract: A 4-aryl-4-substituted pyrazolidine-3,5-dione derivative represented by the formula (1) is useful as an effective component of a miticide, insecticide or herbicide wherein R1 and R2 are each independently alkyl group having 1 to 4 carbon atoms, or R1 and R2, when taken together, represent saturated or unsaturated bivalent hydrocarbon group having 3 or 4 carbon atoms which may optionally be substituted with alkyl group having 1 to 4 carbon atoms, or halogen atom, X is alkyl group having 1 to 4 carbon atoms, haloalkyl group having 1 to 4 carbon atoms or halogen atom, Y is halogen atom or nitro group, and n is an integer of 0 to 3.
    Type: Grant
    Filed: April 19, 2000
    Date of Patent: January 30, 2001
    Assignee: Otsuka Kagaku Kabushiki Kaisha
    Inventors: Nobuyoshi Takahashi, Hirofumi Nakagawa, Yoshinori Endo