Abstract: Pyrazolone derivative formulations are provided. The formulations include a pyrazolone derivative active agent, e.g., edaravone, and an amphiphilic solubilizing agent. Also provided are methods of making and using the subject formulations.

Abstract: A salt represented by formula (4) produced via a first step of dehydrating a mixture containing a hydrocarbon solvent and an alkali metal hydroxide represented by formula: A+ OH?, and a second step or reacting the mixture dehydrated in the first step with a compound represented by formula (2) is useful for producing an active ingredient of a plant disease control agent.

Abstract: A salt represented by formula (4) produced via a first step of dehydrating a mixture containing a hydrocarbon solvent and an alkali metal hydroxide represented by formula: A+ OH?, and a second step or reacting the mixture dehydrated in the first step with a compound represented by formula (2) is useful for producing an active ingredient of a plant disease control agent.

Abstract: Pyrazolone derivative emulsion formulations are provided. The emulsion formulations include a pyrazolone derivative active agent, e.g., Edaravone, oil, water and an emulsifier. Also provided are methods of making and using the subject emulsion formulations.

Abstract: Magenta chromophore dyes which are stabilized by adding steric hindering groups to protect the imino carbons; nonlimiting examples of the steric hindering groups being phenyl, methyl, ethyl, isopropyl, fluoride, chloride, bromide and iodide groups.

Abstract: The present invention relates to a plant diseases controlling composition containing as active ingredients: the pyrazolinone derivative represented by Chemical Formula: wherein R1 represents halogen or methyl optionally substituted with halogen, R2 represents hydrogen, halogen or methyl optionally substituted with halogen, R3 represents isopropyl, sec-butyl, 1-ethylpropyl, 1-methylbutyl, tert-butyl or 1,1-dimethylpropyl, R4 representing oxygen or sulfur, R5 represents C1-C5 alkyl, C2-C5 alkynyl or C3-C5 alkenyl, and at least one imide compound selected from N-(3,5-dichlorophenyl)-1,2-dimethylcyclopropane-1,2-dicarboximide, 3-(3,5-dichlorophenyl)-N-(1-methylethyl)-2,4-dioxo-1-imidazolidinecarboxamide and 3-(3,5-dichlorophenyl)-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione; and a plant diseases controlling method comprising applying said pyrazolinone derivative with said imide compound. The present invention can effectively control plant diseases.

Abstract: Compounds of formula I wherein W is optionally substituted alkylene; Y is N or CRa; Ra is hydrogen, halogen or alkyl; R1n represents hydrogen or 1 to 4 substituents; R2 is hydrogen, nitro, cyano, halogen, alkyl, haloalkyl, alkoxy, alkylthio or alkoxycarbonyl; R3 is optionally substituted alkyl, cycloalkyl, aryl or hetaryl; A is N—OR4, CH—OR4, CH—SR4 or CHR5; R4 is alkyl or haloalkyl; R5 is halogen, alkyl or haloalkyl; methods and intermediates for their preparation. The compounds and compositions comprising them are useful for combating animal pests and harmful fungi.

Abstract: The pyrazolinone derivatives represented by the formula [I]: [wherein R1, R2, R3, R4 and R5 may be identical or different and represent independently a hydrogen atom, a halogen atom, an alkyl group, a haloalkyl group, an alkoxyl group, etc.; R6 represents an optionally substituted alkyl group, etc.; X represents an optionally substituted alkyl group, etc,; and Y represents an oxygen atom or a sulfur atom] are provided.