Halogen Attached Directly Or Indirectly To The Cyclic Anhydride By Nonionic Bonding Patents (Class 549/254)
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Publication number: 20120190579Abstract: The present invention relates to a product comprising a solid substrate and a moiety of formula (I) linked thereto: wherein X, X? and R are as defined herein. The product is useful for immobilising target molecules such as molecules of biochemical interest to solid substrates for numerous applications, such as affinity chromatography, ELISA, biotechnological assay techniques and solid phase peptide synthesis.Type: ApplicationFiled: August 9, 2010Publication date: July 26, 2012Applicant: UCL Business PLCInventors: Mark Smith, Stephen Caddick, James Baker
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Patent number: 6984739Abstract: An inner salt of L-carnitine is prepared by reduction, with a suitable reducing agent, of a compound of formula (I): where X1 and X2, which may be the same or different, are hydroxy, C1–C4 alkoxy, phenoxy, halogen, or X1 and X2, when taken together are an oxygen atom and the resulting compound is a derivative of succinic anhydride; Y is halogen, a mesyloxy or a tosyloxy group, and subsequent treatment with water, then with a base and then with trimethylamine.Type: GrantFiled: November 20, 2003Date of Patent: January 10, 2006Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.Inventors: Piero Melloni, Alberto Cerri, Marco Santagostino
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Patent number: 6936722Abstract: (Per)haloethers having formula: X—(Rf)L—O—CF2CF2—O—CX1X2—CFX3X4??(I), process for obtaining them and hypofluorites usable in the synthesis of said (per)haloethers.Type: GrantFiled: February 4, 2003Date of Patent: August 30, 2005Assignee: Solvay Solexis S.p.A.Inventors: Giovanni Fontana, Walter Navarrini
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Patent number: 6677476Abstract: An inner salt of L-carnitine is prepared by reduction, with a suitable reducing agent, of a compound of formula (I): where X1 and X2, which may be the same or different, are hydroxy, C1-C4 alkoxy, phenoxy, halogen, or X1 and X2, when taken together are an oxygen atom and the resulting compound is a derivative of succinic anhydride; Y is halogen, the mesyloxy or the tosyloxy group: and subsequent treatment with water, then with a base and then with trimethylamine.Type: GrantFiled: November 6, 2001Date of Patent: January 13, 2004Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.Inventors: Piero Melloni, Alberto Cerri, Marco Santagostino
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Patent number: 6579658Abstract: Polymers comprising recurring units of fluorinated maleic anhydride and/or fluorinated maleimide are novel. Using the polymers, resist compositions featuring low absorption of F2 excimer laser light are obtained.Type: GrantFiled: February 15, 2001Date of Patent: June 17, 2003Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Jun Hatakeyama, Jun Watanabe, Yuji Harada
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Patent number: 5414095Abstract: An anhydride-functional primary alkyl halide having the structure: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.2 are each individually hydrogen or methyl, and the total number of carbon atoms in R.sup.1 and R.sup.2 and R.sup.3 combined is two or less. The compounds are useful in the synthesis of polymers, etc.Type: GrantFiled: January 3, 1994Date of Patent: May 9, 1995Assignee: The Sherwin-Williams CompanyInventor: Rodney M. Harris
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Patent number: 5225573Abstract: Tetrabromophthalic anhydride and the corresponding free acid are propared by oxidizing in the liquid phase a compound of the formula ##STR1## each of A and A' is independently selected from oxygen, OH or acetoxy; each of R and R' is independently selected from H, OH, alkyl, alkylidene or oxygen;x is 0 or 1; y is 3-x; and R.sub.y and R'.sub.y may together form a closed alicyclic or heterocyclic ring structure.Mixtures of two or more compounds of formula (I), optionally in the presence of an oxidation catalyst, can also be employed as the starting material.Type: GrantFiled: December 10, 1991Date of Patent: July 6, 1993Assignee: Bromine Compounds LimitedInventors: Leonard Shorr, Michael Peled
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Patent number: 5206392Abstract: A process for making acrylmaleic acid and arylmaleic anhydride derivative useful as intermediates for the preparation of arylmaleimides in the synthesis of compounds having activity in the central nervous system. The process involves reacting arylacetonitriles with glyoxylic acid to provide novel intermediate 3-aryl-3-cyanopropeneoates which may be converted to the arylmaleic acid and arylmaleic anhydride derivatives.Type: GrantFiled: April 27, 1992Date of Patent: April 27, 1993Assignee: American Cyanamid CompanyInventor: William D. Dean
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Patent number: 5112993Abstract: A process for producing difluoromaleic anhydride by reacting sulfur trioxide with a fluorinated precursor selected from the group consisting of hexafluoro-2,5-dihydrofuran, hexafluoro-2,5-dihydrothiophene, difluoro-2,5-dihydrothiophene-2,5-dione and tetrafluoro-2,5-dihydrothiophene-2-one. Also disclosed are the compounds difluoro-2,5-dihydrothiophene-2,5-dione and tetrafluoro-2,5-dihydrothiophene-2-one. Difluoromaleic anhydride is useful for example as a component of fluoropolymers.Type: GrantFiled: November 14, 1989Date of Patent: May 12, 1992Assignee: E. I. Du Pont de Nemours and CompanyInventor: Carl G. Krespan
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Patent number: 4596867Abstract: Di-substituted maleic anhydride compounds are disclosed of the structural formula ##STR1## wherein R and R.sup.1 are selected from the group consisting of aliphatic and phenyl moieties, and R.sup.2 is a divalent aromatic moiety. Polyamide-imide polymers, polyimide polymers and vinyl copolymers derived therefrom are also disclosed.Type: GrantFiled: July 12, 1984Date of Patent: June 24, 1986Assignee: Standard Oil Company (Indiana)Inventors: Ellis K. Fields, Mark L. Winzenburg, Steven J. Behrend
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Patent number: 4526986Abstract: Quaternary ammonium compounds containing anhydride groups are prepared by halogenating dimethylmaleic anhydride and reacting the halogenated product with a tertiary amine. The products are useful as surfactants, biocides and as cosurfactants in enhanced oil recovery.Type: GrantFiled: April 13, 1983Date of Patent: July 2, 1985Assignee: Standard Oil Company (Indiana)Inventors: Ellis K. Fields, Mark L. Winzenburg
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Patent number: 4431825Abstract: Products typified by alkenyl-substituted succinic acid anhydrides are prepared by reacting olefin oligomers with anhydrides of unsaturated aliphatic polycarboxylic acids in the presence of ferric chloride, ferric bromide, stannic chloride, or phosphoric acid H.sub.3 PO.sub.4 as catalyst.Type: GrantFiled: April 12, 1982Date of Patent: February 14, 1984Assignee: Texaco Inc.Inventor: Justin C. Powell