Halogen Attached Directly Or Indirectly To The Cyclic Anhydride By Nonionic Bonding Patents (Class 549/254)
  • Publication number: 20120190579
    Abstract: The present invention relates to a product comprising a solid substrate and a moiety of formula (I) linked thereto: wherein X, X? and R are as defined herein. The product is useful for immobilising target molecules such as molecules of biochemical interest to solid substrates for numerous applications, such as affinity chromatography, ELISA, biotechnological assay techniques and solid phase peptide synthesis.
    Type: Application
    Filed: August 9, 2010
    Publication date: July 26, 2012
    Applicant: UCL Business PLC
    Inventors: Mark Smith, Stephen Caddick, James Baker
  • Patent number: 6984739
    Abstract: An inner salt of L-carnitine is prepared by reduction, with a suitable reducing agent, of a compound of formula (I): where X1 and X2, which may be the same or different, are hydroxy, C1–C4 alkoxy, phenoxy, halogen, or X1 and X2, when taken together are an oxygen atom and the resulting compound is a derivative of succinic anhydride; Y is halogen, a mesyloxy or a tosyloxy group, and subsequent treatment with water, then with a base and then with trimethylamine.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: January 10, 2006
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Piero Melloni, Alberto Cerri, Marco Santagostino
  • Patent number: 6936722
    Abstract: (Per)haloethers having formula: X—(Rf)L—O—CF2CF2—O—CX1X2—CFX3X4??(I), process for obtaining them and hypofluorites usable in the synthesis of said (per)haloethers.
    Type: Grant
    Filed: February 4, 2003
    Date of Patent: August 30, 2005
    Assignee: Solvay Solexis S.p.A.
    Inventors: Giovanni Fontana, Walter Navarrini
  • Patent number: 6677476
    Abstract: An inner salt of L-carnitine is prepared by reduction, with a suitable reducing agent, of a compound of formula (I): where X1 and X2, which may be the same or different, are hydroxy, C1-C4 alkoxy, phenoxy, halogen, or X1 and X2, when taken together are an oxygen atom and the resulting compound is a derivative of succinic anhydride; Y is halogen, the mesyloxy or the tosyloxy group: and subsequent treatment with water, then with a base and then with trimethylamine.
    Type: Grant
    Filed: November 6, 2001
    Date of Patent: January 13, 2004
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Piero Melloni, Alberto Cerri, Marco Santagostino
  • Patent number: 6579658
    Abstract: Polymers comprising recurring units of fluorinated maleic anhydride and/or fluorinated maleimide are novel. Using the polymers, resist compositions featuring low absorption of F2 excimer laser light are obtained.
    Type: Grant
    Filed: February 15, 2001
    Date of Patent: June 17, 2003
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Jun Hatakeyama, Jun Watanabe, Yuji Harada
  • Patent number: 5414095
    Abstract: An anhydride-functional primary alkyl halide having the structure: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.2 are each individually hydrogen or methyl, and the total number of carbon atoms in R.sup.1 and R.sup.2 and R.sup.3 combined is two or less. The compounds are useful in the synthesis of polymers, etc.
    Type: Grant
    Filed: January 3, 1994
    Date of Patent: May 9, 1995
    Assignee: The Sherwin-Williams Company
    Inventor: Rodney M. Harris
  • Patent number: 5225573
    Abstract: Tetrabromophthalic anhydride and the corresponding free acid are propared by oxidizing in the liquid phase a compound of the formula ##STR1## each of A and A' is independently selected from oxygen, OH or acetoxy; each of R and R' is independently selected from H, OH, alkyl, alkylidene or oxygen;x is 0 or 1; y is 3-x; and R.sub.y and R'.sub.y may together form a closed alicyclic or heterocyclic ring structure.Mixtures of two or more compounds of formula (I), optionally in the presence of an oxidation catalyst, can also be employed as the starting material.
    Type: Grant
    Filed: December 10, 1991
    Date of Patent: July 6, 1993
    Assignee: Bromine Compounds Limited
    Inventors: Leonard Shorr, Michael Peled
  • Patent number: 5206392
    Abstract: A process for making acrylmaleic acid and arylmaleic anhydride derivative useful as intermediates for the preparation of arylmaleimides in the synthesis of compounds having activity in the central nervous system. The process involves reacting arylacetonitriles with glyoxylic acid to provide novel intermediate 3-aryl-3-cyanopropeneoates which may be converted to the arylmaleic acid and arylmaleic anhydride derivatives.
    Type: Grant
    Filed: April 27, 1992
    Date of Patent: April 27, 1993
    Assignee: American Cyanamid Company
    Inventor: William D. Dean
  • Patent number: 5112993
    Abstract: A process for producing difluoromaleic anhydride by reacting sulfur trioxide with a fluorinated precursor selected from the group consisting of hexafluoro-2,5-dihydrofuran, hexafluoro-2,5-dihydrothiophene, difluoro-2,5-dihydrothiophene-2,5-dione and tetrafluoro-2,5-dihydrothiophene-2-one. Also disclosed are the compounds difluoro-2,5-dihydrothiophene-2,5-dione and tetrafluoro-2,5-dihydrothiophene-2-one. Difluoromaleic anhydride is useful for example as a component of fluoropolymers.
    Type: Grant
    Filed: November 14, 1989
    Date of Patent: May 12, 1992
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Carl G. Krespan
  • Patent number: 4596867
    Abstract: Di-substituted maleic anhydride compounds are disclosed of the structural formula ##STR1## wherein R and R.sup.1 are selected from the group consisting of aliphatic and phenyl moieties, and R.sup.2 is a divalent aromatic moiety. Polyamide-imide polymers, polyimide polymers and vinyl copolymers derived therefrom are also disclosed.
    Type: Grant
    Filed: July 12, 1984
    Date of Patent: June 24, 1986
    Assignee: Standard Oil Company (Indiana)
    Inventors: Ellis K. Fields, Mark L. Winzenburg, Steven J. Behrend
  • Patent number: 4526986
    Abstract: Quaternary ammonium compounds containing anhydride groups are prepared by halogenating dimethylmaleic anhydride and reacting the halogenated product with a tertiary amine. The products are useful as surfactants, biocides and as cosurfactants in enhanced oil recovery.
    Type: Grant
    Filed: April 13, 1983
    Date of Patent: July 2, 1985
    Assignee: Standard Oil Company (Indiana)
    Inventors: Ellis K. Fields, Mark L. Winzenburg
  • Patent number: 4431825
    Abstract: Products typified by alkenyl-substituted succinic acid anhydrides are prepared by reacting olefin oligomers with anhydrides of unsaturated aliphatic polycarboxylic acids in the presence of ferric chloride, ferric bromide, stannic chloride, or phosphoric acid H.sub.3 PO.sub.4 as catalyst.
    Type: Grant
    Filed: April 12, 1982
    Date of Patent: February 14, 1984
    Assignee: Texaco Inc.
    Inventor: Justin C. Powell