Double Bond Between Ring Members Of The Cyclic Anhydride Patents (Class 549/261)
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Publication number: 20150018490Abstract: Provided is a surface-treated carbon nanotube having few surface fractures, not reducing the molecular weight of the resin to be mixed and having excellent extrudability. In the surface-treated carbon nanotube, the thermal reduction amount at 600° C. in a nitrogen atmosphere is 0.2 to 40%, the surface oxygen concentration measured by X-ray photoelectron spectroscopy (XPS) is 1.5 to 40 atm % and the surface sulfur concentration is less than 0.1 atm %.Type: ApplicationFiled: March 5, 2013Publication date: January 15, 2015Inventors: Aya Takagiwa, Teruaki Sakuma, Yasukazu Shikano, Kazuya Noda
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Publication number: 20140128584Abstract: We describe anhydride compounds suitable for physiologically labile modification of amine-containing molecules. The described anhydrides form reversible linkages having desirable kinetics for in vivo delivery of biologically active molecules. Also described are endosomolytic polymers formed by modification of membrane active polyamines with the described anhydrides.Type: ApplicationFiled: May 31, 2012Publication date: May 8, 2014Applicant: ARROWHEAD MADISON INC.Inventors: Andrei V. Blokhin, David B. Rozema, Jonathan D. Benson, Jeffrey C. Carlson
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Publication number: 20130096323Abstract: The present invention relates to a compound derived from mycelium of Antrodia camphorata. The present invention also relates to the composition or mycelium comprising the compounds of the invention. The composition of the invention decreases systolic blood pressure and increases high density lipoprotein.Type: ApplicationFiled: October 12, 2012Publication date: April 18, 2013Applicant: SIMPSON BIOTECH CO., LTD.Inventor: Simpson Biotech Co., Ltd.
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Patent number: 8273903Abstract: The disclosure provides a method for preparing the citraconic anhydride and a method for isomerizing/dehydrating itaconic acid. The method for preparing the citraconic anhydride includes the following steps: providing itaconic acid as a starting material; and subjecting the itaconic acid to an isomerization/dehydration reaction in the presence of a catalyst to obtain the citraconic anhydride, wherein the catalyst includes a heteropolyacid or heteropolyacid salt.Type: GrantFiled: December 30, 2010Date of Patent: September 25, 2012Assignee: Industrial Technology Research InstituteInventors: Hsi-Yen Hsu, Yu-Shan Chao
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Publication number: 20110160466Abstract: The disclosure provides a method for preparing the citraconic anhydride and a method for isomerizing/dehydrating itaconic acid. The method for preparing the citraconic anhydride includes the following steps: providing itaconic acid as a starting material; and subjecting the itaconic acid to an isomerization/dehydration reaction in the presence of a catalyst to obtain the citraconic anhydride, wherein the catalyst includes a heteropolyacid or heteropolyacid salt.Type: ApplicationFiled: December 30, 2010Publication date: June 30, 2011Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Hsi-Yen Hsu, Yu-Shan Chao
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Patent number: 7879906Abstract: The invention provides compounds of Formula (I), pharmaceutical compositions and methods of synthesis thereof.Type: GrantFiled: November 21, 2007Date of Patent: February 1, 2011Assignee: Anchen Laboratories, Inc.Inventors: Jenn-Tsang Hwang, Chrong-Shiong Hwang, Yow-Lone Chang, Chung-Niang Yao
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Publication number: 20100324309Abstract: The present invention relates to a compound derived from mycelium of Antrodia camphorata. The present invention also relates to the composition or mycelium comprising the compounds of the invention. The composition of the invention decreases systolic blood pressure and increases high density lipoprotein.Type: ApplicationFiled: July 21, 2010Publication date: December 23, 2010Applicant: SIMPSON BIOTECH CO., LTD.Inventors: Masao Hattori, Chia-Chin Sheu
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Patent number: 6649774Abstract: Processes for producing citraconic anhydride and citraconic acid using porous materials with specific surface acidities and surface areas are described. The preferred catalyst is a porous gamma alumina. Itaconic acid is produced from citraconic acid. Itaconic acid is an intermediate to a variety of compounds including polymers.Type: GrantFiled: August 23, 2002Date of Patent: November 18, 2003Assignee: Board of Trustees of Michigan State UniversityInventors: Dennis J. Miller, Dushyant Shekhawat, Kirthivasan Nagarajan, James E. Jackson
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Method and apparatus for direct oxygen injection with a reactant stream into a fluidized bed reactor
Patent number: 5895817Abstract: A system provides an oxygen-bearing gas and gaseous reactant stream to a fluidized bed reactor using a sparger to entrain the oxygen-bearing gas into the reactant gas stream. A feed line couples the sparger to the reactor's fluidized bed and introduces the reactant gas stream and entrained oxygen-bearing gas directly into contact with the fluidized bed. A controller controls and maintains both the amount of oxygen-bearing gas and the gaseous reactant above an upper flammability limit, preferably with a safety margin of at least 10%.Type: GrantFiled: June 19, 1997Date of Patent: April 20, 1999Assignee: Praxair Technology, Inc.Inventor: Matthew Lincoln Wagner -
Patent number: 5670659Abstract: Citraconic anhydride is prepared in a single step by heating itaconic acid, optionally in an inert organic solvent medium, in the presence of a catalytically effective amount of an at least partially organic acid/base catalyst compound having a pKa ranging from 4 to 10, in particular a salt catalyst such as pyridinium tosylate, itaconate or hydrochloride, ammonium itaconate, or phosphinium hydrobromide.Type: GrantFiled: January 30, 1995Date of Patent: September 23, 1997Assignee: Rhone-Poulenc ChimieInventors: Michel Alas, Alain Sigismondi, Philippe-Jean Tirel
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Patent number: 5532384Abstract: Hydrocarbon derivatives are produced by contacting a hydrocarbon with oxygen obtained from an air separation unit in the presence of a partial oxidation reaction catalyst. After separation of the hydrocarbon derivative from the reactor effluent, unreacted hydrocarbon is recovered from the effluent by adsorbing the unreacted hydrocarbon onto an adsorbent at superatmospheric pressure and removing the adsorbed hydrocarbon from the adsorbent by depressurizing said adsorbent and purging the adsorbent with nitrogen obtained from the air separation unit. The recovered unreacted hydrocarbon is recycled to the partial oxidation reactor.Type: GrantFiled: May 9, 1994Date of Patent: July 2, 1996Assignee: The BOC Group, Inc.Inventors: Arthur Shirley, Ramakrishnan Ramachandran
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Patent number: 5420157Abstract: This invention relates to pharmaceutical compounds of structural formulae (I) and (II): ##STR1## and compositions and methods of treatment utilizing these compounds to inhibit farnesyl protein transferase and farnesylation of the oncogene protein Ras.Type: GrantFiled: December 16, 1991Date of Patent: May 30, 1995Assignee: Merck & Co., Inc.Inventors: Sheo B. Singh, Gerald F. Bills, Russell B. Lingham, Keith C. Silverman, Deborah L. Zink
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Patent number: 5262548Abstract: An improvement in the oxidation catalyst used for the partial oxidation of n-butane and containing vanadium and phosphorus, zinc and lithium mixed oxides which comprises adding a molybdenum compound modifier in an amount of from about 0.005 to 0.025/1 Mo/V to the catalyst during the digestion of the reduced vanadium compound by concentrated phosphoric acid. The addition of Mo produces a catalyst which is very stable more active system and longer lived than the unmodified catalyst.Type: GrantFiled: August 3, 1992Date of Patent: November 16, 1993Assignee: Scientific Design Company, Inc.Inventor: Bruno J. Barone
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Patent number: 5206392Abstract: A process for making acrylmaleic acid and arylmaleic anhydride derivative useful as intermediates for the preparation of arylmaleimides in the synthesis of compounds having activity in the central nervous system. The process involves reacting arylacetonitriles with glyoxylic acid to provide novel intermediate 3-aryl-3-cyanopropeneoates which may be converted to the arylmaleic acid and arylmaleic anhydride derivatives.Type: GrantFiled: April 27, 1992Date of Patent: April 27, 1993Assignee: American Cyanamid CompanyInventor: William D. Dean
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Patent number: 5179215Abstract: An improved process is provided for the production of a petrochemical by the vapor phase reaction of a hydrocarbon with an oxygen-containing gas in the presence of a suitable catalyst to produce a flammable gaseous product stream comprising the desired petrochemical, unreacted hydrocarbon, oxygen, carbon monoxide and carbon dioxide. In the improved process, a cooled or liquefied inert gas is injected as a quench fluid into the gaseous product stream exiting the hydrocarbon oxidation reactor, thereby cooling the stream to a temperature below the autoignition temperature of the flammable components of the stream, the petrochemical is recovered from the gaseous product and unreacted hydrocarbon is removed from the gaseous product and recycled to the reactor.Type: GrantFiled: February 27, 1991Date of Patent: January 12, 1993Assignee: The BOC Group, Inc.Inventors: Ramakrishnan Ramachandran, Donald L. MacLean
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Patent number: 5126463Abstract: This invention provides a process for the production of an anhydride by the vapor phase reaction of a hydrocarbon with substantially pure oxygen in the presence of a suitable catalyst. In the improved process, the anhydride product is removed, carbon monoxide, present in the reactor effluent as a by-product, is oxidized to carbon dioxide and part of the gaseous effluent, comprised mainly of carbon dioxide and unreacted hydrocarbon, is recycled to the reactor. Removal of carbon monoxide from the recycle stream reduces the hazard of a fire or explosion in the reactor or associated equipment. The use of carbon dioxide as the principal diluent increases heat removal from the reactor, thereby increasing the production capacity of the reactor.Type: GrantFiled: October 31, 1990Date of Patent: June 30, 1992Assignee: The BOC Group, Inc.Inventors: Ramakrishnan Ramachandran, Arthur I. Shirley, Lien-Lung Sheu
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Patent number: 4644069Abstract: The reaction of maleic acid, fumaric acid and/or maleic anhydride in the presence of N-acylated heterocyclic amidines and at elevated temperature affords dimethylmaleic anhydride in good yield. Catalytic amounts of the amidine employed are sufficient for said reaction.Type: GrantFiled: August 6, 1985Date of Patent: February 17, 1987Assignee: Ciba-Geigy CorporationInventors: Marcus Baumann, Werner Breitenstein
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Patent number: 4639531Abstract: The reaction of maleic acid, fumaric acid and/or maleic anhydride at elevated temperature and in the presence of catalytic amounts of a heterocyclic amidine or a salt thereof with protonic acids affords dimethylmaleic anhydride in good yield.Type: GrantFiled: August 6, 1985Date of Patent: January 27, 1987Assignee: Ciba-Geigy CorporationInventors: Marcus Baumann, Werner Breitenstein
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Patent number: 4596867Abstract: Di-substituted maleic anhydride compounds are disclosed of the structural formula ##STR1## wherein R and R.sup.1 are selected from the group consisting of aliphatic and phenyl moieties, and R.sup.2 is a divalent aromatic moiety. Polyamide-imide polymers, polyimide polymers and vinyl copolymers derived therefrom are also disclosed.Type: GrantFiled: July 12, 1984Date of Patent: June 24, 1986Assignee: Standard Oil Company (Indiana)Inventors: Ellis K. Fields, Mark L. Winzenburg, Steven J. Behrend
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Patent number: 4562264Abstract: A process for the recovery of five-membered ring dicarboxylic acid anhydrides from aqueous solutions of the corresponding dicarboxylic acids which entails (a) washing the aqueous solution of the dicarboxylic acid with a water-insoluble tertiary amine, and separating the resulting amine-acid salt from the water layer; and (b) adding an aromatic hydrocarbon entrainer for the water, removing the entrainer/water azeotrope by distillation and separating the five-membered ring dicarboxylic acid anhydride after phase separation; or adding an aliphatic hydrocarbon entrainer for the water, removing a ternary azeotropic mixture consisting of a hydrolytically stable anhydride, water and entrainer by distillation and separating the five-membered ring dicarboxylic acid anhydride after phase separation.Type: GrantFiled: August 31, 1984Date of Patent: December 31, 1985Assignee: Chemische Werke Huls AktiengesellschaftInventors: Fritz Gude, Ferdinand von Praun
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Patent number: 4554360Abstract: Provided is a process for converting an aromatic compound to prepare an iodoarene, Ar--I, and an aryl compound which is a compound wherein an unsaturated compound is bonded directly to an aryl group, Ar, which process comprises reacting a diaryliodonium salt represented by general formula (I)[Ar--I.sup..sym. --Ar]X.sup..crclbar. (I)wherein Ar is an aryl group which may be substituted and two Ar's are identical and X.sup..crclbar. is a counter ion inert to the reaction with the unsaturated compound in a solvent in the presence of a transition metal catalyst and a base or a reducing metal, said reaction being carried out at a temperature not higher than 80.degree. C. and/or by using at least one of the base, the reducing metal and the unsaturated compound in an amount not more than 1.Type: GrantFiled: March 29, 1984Date of Patent: November 19, 1985Assignee: Nippon Petrochemicals Company, LimitedInventors: Yasuo Yamazaki, Takehiko Suzuki, Isoo Shimizu, Yasuo Matsumura
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Patent number: 4434071Abstract: Reaction of maleic acid anhydride and polyisobutylene is improved by use, as catalyst, of a complex of polyisobutylene and a 1,3-dibromo dialkylhydantoin.Type: GrantFiled: January 15, 1982Date of Patent: February 28, 1984Assignee: Texaco Inc.Inventor: Justin C. Powell