Double Bond Between Ring Members Of The Cyclic Anhydride Patents (Class 549/261)
  • Publication number: 20150018490
    Abstract: Provided is a surface-treated carbon nanotube having few surface fractures, not reducing the molecular weight of the resin to be mixed and having excellent extrudability. In the surface-treated carbon nanotube, the thermal reduction amount at 600° C. in a nitrogen atmosphere is 0.2 to 40%, the surface oxygen concentration measured by X-ray photoelectron spectroscopy (XPS) is 1.5 to 40 atm % and the surface sulfur concentration is less than 0.1 atm %.
    Type: Application
    Filed: March 5, 2013
    Publication date: January 15, 2015
    Inventors: Aya Takagiwa, Teruaki Sakuma, Yasukazu Shikano, Kazuya Noda
  • Publication number: 20140128584
    Abstract: We describe anhydride compounds suitable for physiologically labile modification of amine-containing molecules. The described anhydrides form reversible linkages having desirable kinetics for in vivo delivery of biologically active molecules. Also described are endosomolytic polymers formed by modification of membrane active polyamines with the described anhydrides.
    Type: Application
    Filed: May 31, 2012
    Publication date: May 8, 2014
    Applicant: ARROWHEAD MADISON INC.
    Inventors: Andrei V. Blokhin, David B. Rozema, Jonathan D. Benson, Jeffrey C. Carlson
  • Publication number: 20130096323
    Abstract: The present invention relates to a compound derived from mycelium of Antrodia camphorata. The present invention also relates to the composition or mycelium comprising the compounds of the invention. The composition of the invention decreases systolic blood pressure and increases high density lipoprotein.
    Type: Application
    Filed: October 12, 2012
    Publication date: April 18, 2013
    Applicant: SIMPSON BIOTECH CO., LTD.
    Inventor: Simpson Biotech Co., Ltd.
  • Patent number: 8273903
    Abstract: The disclosure provides a method for preparing the citraconic anhydride and a method for isomerizing/dehydrating itaconic acid. The method for preparing the citraconic anhydride includes the following steps: providing itaconic acid as a starting material; and subjecting the itaconic acid to an isomerization/dehydration reaction in the presence of a catalyst to obtain the citraconic anhydride, wherein the catalyst includes a heteropolyacid or heteropolyacid salt.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: September 25, 2012
    Assignee: Industrial Technology Research Institute
    Inventors: Hsi-Yen Hsu, Yu-Shan Chao
  • Publication number: 20110160466
    Abstract: The disclosure provides a method for preparing the citraconic anhydride and a method for isomerizing/dehydrating itaconic acid. The method for preparing the citraconic anhydride includes the following steps: providing itaconic acid as a starting material; and subjecting the itaconic acid to an isomerization/dehydration reaction in the presence of a catalyst to obtain the citraconic anhydride, wherein the catalyst includes a heteropolyacid or heteropolyacid salt.
    Type: Application
    Filed: December 30, 2010
    Publication date: June 30, 2011
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Hsi-Yen Hsu, Yu-Shan Chao
  • Patent number: 7879906
    Abstract: The invention provides compounds of Formula (I), pharmaceutical compositions and methods of synthesis thereof.
    Type: Grant
    Filed: November 21, 2007
    Date of Patent: February 1, 2011
    Assignee: Anchen Laboratories, Inc.
    Inventors: Jenn-Tsang Hwang, Chrong-Shiong Hwang, Yow-Lone Chang, Chung-Niang Yao
  • Publication number: 20100324309
    Abstract: The present invention relates to a compound derived from mycelium of Antrodia camphorata. The present invention also relates to the composition or mycelium comprising the compounds of the invention. The composition of the invention decreases systolic blood pressure and increases high density lipoprotein.
    Type: Application
    Filed: July 21, 2010
    Publication date: December 23, 2010
    Applicant: SIMPSON BIOTECH CO., LTD.
    Inventors: Masao Hattori, Chia-Chin Sheu
  • Patent number: 6649774
    Abstract: Processes for producing citraconic anhydride and citraconic acid using porous materials with specific surface acidities and surface areas are described. The preferred catalyst is a porous gamma alumina. Itaconic acid is produced from citraconic acid. Itaconic acid is an intermediate to a variety of compounds including polymers.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: November 18, 2003
    Assignee: Board of Trustees of Michigan State University
    Inventors: Dennis J. Miller, Dushyant Shekhawat, Kirthivasan Nagarajan, James E. Jackson
  • Patent number: 5895817
    Abstract: A system provides an oxygen-bearing gas and gaseous reactant stream to a fluidized bed reactor using a sparger to entrain the oxygen-bearing gas into the reactant gas stream. A feed line couples the sparger to the reactor's fluidized bed and introduces the reactant gas stream and entrained oxygen-bearing gas directly into contact with the fluidized bed. A controller controls and maintains both the amount of oxygen-bearing gas and the gaseous reactant above an upper flammability limit, preferably with a safety margin of at least 10%.
    Type: Grant
    Filed: June 19, 1997
    Date of Patent: April 20, 1999
    Assignee: Praxair Technology, Inc.
    Inventor: Matthew Lincoln Wagner
  • Patent number: 5670659
    Abstract: Citraconic anhydride is prepared in a single step by heating itaconic acid, optionally in an inert organic solvent medium, in the presence of a catalytically effective amount of an at least partially organic acid/base catalyst compound having a pKa ranging from 4 to 10, in particular a salt catalyst such as pyridinium tosylate, itaconate or hydrochloride, ammonium itaconate, or phosphinium hydrobromide.
    Type: Grant
    Filed: January 30, 1995
    Date of Patent: September 23, 1997
    Assignee: Rhone-Poulenc Chimie
    Inventors: Michel Alas, Alain Sigismondi, Philippe-Jean Tirel
  • Patent number: 5532384
    Abstract: Hydrocarbon derivatives are produced by contacting a hydrocarbon with oxygen obtained from an air separation unit in the presence of a partial oxidation reaction catalyst. After separation of the hydrocarbon derivative from the reactor effluent, unreacted hydrocarbon is recovered from the effluent by adsorbing the unreacted hydrocarbon onto an adsorbent at superatmospheric pressure and removing the adsorbed hydrocarbon from the adsorbent by depressurizing said adsorbent and purging the adsorbent with nitrogen obtained from the air separation unit. The recovered unreacted hydrocarbon is recycled to the partial oxidation reactor.
    Type: Grant
    Filed: May 9, 1994
    Date of Patent: July 2, 1996
    Assignee: The BOC Group, Inc.
    Inventors: Arthur Shirley, Ramakrishnan Ramachandran
  • Patent number: 5420157
    Abstract: This invention relates to pharmaceutical compounds of structural formulae (I) and (II): ##STR1## and compositions and methods of treatment utilizing these compounds to inhibit farnesyl protein transferase and farnesylation of the oncogene protein Ras.
    Type: Grant
    Filed: December 16, 1991
    Date of Patent: May 30, 1995
    Assignee: Merck & Co., Inc.
    Inventors: Sheo B. Singh, Gerald F. Bills, Russell B. Lingham, Keith C. Silverman, Deborah L. Zink
  • Patent number: 5262548
    Abstract: An improvement in the oxidation catalyst used for the partial oxidation of n-butane and containing vanadium and phosphorus, zinc and lithium mixed oxides which comprises adding a molybdenum compound modifier in an amount of from about 0.005 to 0.025/1 Mo/V to the catalyst during the digestion of the reduced vanadium compound by concentrated phosphoric acid. The addition of Mo produces a catalyst which is very stable more active system and longer lived than the unmodified catalyst.
    Type: Grant
    Filed: August 3, 1992
    Date of Patent: November 16, 1993
    Assignee: Scientific Design Company, Inc.
    Inventor: Bruno J. Barone
  • Patent number: 5206392
    Abstract: A process for making acrylmaleic acid and arylmaleic anhydride derivative useful as intermediates for the preparation of arylmaleimides in the synthesis of compounds having activity in the central nervous system. The process involves reacting arylacetonitriles with glyoxylic acid to provide novel intermediate 3-aryl-3-cyanopropeneoates which may be converted to the arylmaleic acid and arylmaleic anhydride derivatives.
    Type: Grant
    Filed: April 27, 1992
    Date of Patent: April 27, 1993
    Assignee: American Cyanamid Company
    Inventor: William D. Dean
  • Patent number: 5179215
    Abstract: An improved process is provided for the production of a petrochemical by the vapor phase reaction of a hydrocarbon with an oxygen-containing gas in the presence of a suitable catalyst to produce a flammable gaseous product stream comprising the desired petrochemical, unreacted hydrocarbon, oxygen, carbon monoxide and carbon dioxide. In the improved process, a cooled or liquefied inert gas is injected as a quench fluid into the gaseous product stream exiting the hydrocarbon oxidation reactor, thereby cooling the stream to a temperature below the autoignition temperature of the flammable components of the stream, the petrochemical is recovered from the gaseous product and unreacted hydrocarbon is removed from the gaseous product and recycled to the reactor.
    Type: Grant
    Filed: February 27, 1991
    Date of Patent: January 12, 1993
    Assignee: The BOC Group, Inc.
    Inventors: Ramakrishnan Ramachandran, Donald L. MacLean
  • Patent number: 5126463
    Abstract: This invention provides a process for the production of an anhydride by the vapor phase reaction of a hydrocarbon with substantially pure oxygen in the presence of a suitable catalyst. In the improved process, the anhydride product is removed, carbon monoxide, present in the reactor effluent as a by-product, is oxidized to carbon dioxide and part of the gaseous effluent, comprised mainly of carbon dioxide and unreacted hydrocarbon, is recycled to the reactor. Removal of carbon monoxide from the recycle stream reduces the hazard of a fire or explosion in the reactor or associated equipment. The use of carbon dioxide as the principal diluent increases heat removal from the reactor, thereby increasing the production capacity of the reactor.
    Type: Grant
    Filed: October 31, 1990
    Date of Patent: June 30, 1992
    Assignee: The BOC Group, Inc.
    Inventors: Ramakrishnan Ramachandran, Arthur I. Shirley, Lien-Lung Sheu
  • Patent number: 4644069
    Abstract: The reaction of maleic acid, fumaric acid and/or maleic anhydride in the presence of N-acylated heterocyclic amidines and at elevated temperature affords dimethylmaleic anhydride in good yield. Catalytic amounts of the amidine employed are sufficient for said reaction.
    Type: Grant
    Filed: August 6, 1985
    Date of Patent: February 17, 1987
    Assignee: Ciba-Geigy Corporation
    Inventors: Marcus Baumann, Werner Breitenstein
  • Patent number: 4639531
    Abstract: The reaction of maleic acid, fumaric acid and/or maleic anhydride at elevated temperature and in the presence of catalytic amounts of a heterocyclic amidine or a salt thereof with protonic acids affords dimethylmaleic anhydride in good yield.
    Type: Grant
    Filed: August 6, 1985
    Date of Patent: January 27, 1987
    Assignee: Ciba-Geigy Corporation
    Inventors: Marcus Baumann, Werner Breitenstein
  • Patent number: 4596867
    Abstract: Di-substituted maleic anhydride compounds are disclosed of the structural formula ##STR1## wherein R and R.sup.1 are selected from the group consisting of aliphatic and phenyl moieties, and R.sup.2 is a divalent aromatic moiety. Polyamide-imide polymers, polyimide polymers and vinyl copolymers derived therefrom are also disclosed.
    Type: Grant
    Filed: July 12, 1984
    Date of Patent: June 24, 1986
    Assignee: Standard Oil Company (Indiana)
    Inventors: Ellis K. Fields, Mark L. Winzenburg, Steven J. Behrend
  • Patent number: 4562264
    Abstract: A process for the recovery of five-membered ring dicarboxylic acid anhydrides from aqueous solutions of the corresponding dicarboxylic acids which entails (a) washing the aqueous solution of the dicarboxylic acid with a water-insoluble tertiary amine, and separating the resulting amine-acid salt from the water layer; and (b) adding an aromatic hydrocarbon entrainer for the water, removing the entrainer/water azeotrope by distillation and separating the five-membered ring dicarboxylic acid anhydride after phase separation; or adding an aliphatic hydrocarbon entrainer for the water, removing a ternary azeotropic mixture consisting of a hydrolytically stable anhydride, water and entrainer by distillation and separating the five-membered ring dicarboxylic acid anhydride after phase separation.
    Type: Grant
    Filed: August 31, 1984
    Date of Patent: December 31, 1985
    Assignee: Chemische Werke Huls Aktiengesellschaft
    Inventors: Fritz Gude, Ferdinand von Praun
  • Patent number: 4554360
    Abstract: Provided is a process for converting an aromatic compound to prepare an iodoarene, Ar--I, and an aryl compound which is a compound wherein an unsaturated compound is bonded directly to an aryl group, Ar, which process comprises reacting a diaryliodonium salt represented by general formula (I)[Ar--I.sup..sym. --Ar]X.sup..crclbar. (I)wherein Ar is an aryl group which may be substituted and two Ar's are identical and X.sup..crclbar. is a counter ion inert to the reaction with the unsaturated compound in a solvent in the presence of a transition metal catalyst and a base or a reducing metal, said reaction being carried out at a temperature not higher than 80.degree. C. and/or by using at least one of the base, the reducing metal and the unsaturated compound in an amount not more than 1.
    Type: Grant
    Filed: March 29, 1984
    Date of Patent: November 19, 1985
    Assignee: Nippon Petrochemicals Company, Limited
    Inventors: Yasuo Yamazaki, Takehiko Suzuki, Isoo Shimizu, Yasuo Matsumura
  • Patent number: 4434071
    Abstract: Reaction of maleic acid anhydride and polyisobutylene is improved by use, as catalyst, of a complex of polyisobutylene and a 1,3-dibromo dialkylhydantoin.
    Type: Grant
    Filed: January 15, 1982
    Date of Patent: February 28, 1984
    Assignee: Texaco Inc.
    Inventor: Justin C. Powell