Plural Six-membered Hetero Rings Patents (Class 549/415)
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Patent number: 11510992Abstract: Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide. In particular, conjugates can be used in the treatment of viral infections (e.g., influenza viral infections).Type: GrantFiled: April 21, 2021Date of Patent: November 29, 2022Assignee: Cidara Therapeutics, Inc.Inventors: Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Thanh Lam, Leslie W. Tari
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Patent number: 11046676Abstract: The present invention relates to process for the preparation of Empagliflozin or its co-crystals, solvates and/or polymorphs thereof. The present invention also relates to novel intermediates used therein, and process for the preparation thereof. The present invention further relates to process for preparation of amorphous and crystalline form of Empagliflozin.Type: GrantFiled: June 5, 2018Date of Patent: June 29, 2021Assignee: Laurus Labs LimitedInventors: Uma Maheswar Rao Vasireddi, Sanjay Kumar Dehury, Nagaraju Mekala, Jahangeer Baba Shaik, Srinivas Lagadapati
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Patent number: 10793590Abstract: Compounds of formula (I) or formula (II), compositions and methods useful for treating and/or preventing a fungal infections are provided. wherein the substituents are as defined in the appended claims.Type: GrantFiled: June 2, 2017Date of Patent: October 6, 2020Assignees: President and Fellows of Harvard College, Wisconsin Alumni Research Foundation, Universidad de Costa RicaInventors: Ethan Van Arnam, Clarissa Sit, Antonio Ruzzini, Jon Clardy, Cameron Currie, Adrian Alberto Pinto-Tomas
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Patent number: 9668851Abstract: An artificial stomach for replacing the normal stomach of a patient includes a food reservoir adapted to collect food, an inlet connected to a first opening of the food reservoir and further being adapted to upstream connect to the patient's gastrointestinal tract, and an outlet connected to a second opening of the food reservoir and further being adapted to downstream connect to the patient's gastrointestinal tract.Type: GrantFiled: November 8, 2013Date of Patent: June 6, 2017Inventor: Peter Forsell
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Patent number: 9314778Abstract: The present invention provides catalysts, methods, and reactor systems for converting oxygenated hydrocarbons to oxygenated compounds. The invention includes methods for producing cyclic ethers, monooxygenates, dioxygenates, ketones, aldehydes, carboxylic acids, and alcohols from oxygenated hydrocarbons, such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like, using catalysts containing palladium, molybdenum, tin, and tungsten. The oxygenated compounds produced are useful in the production of liquid fuels, chemicals, and other products.Type: GrantFiled: December 30, 2014Date of Patent: April 19, 2016Assignee: Virent, Inc.Inventors: Brian Blank, Randy Cortright, Taylor Beck, Elizabeth Woods, Mike Jehring
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Publication number: 20150141667Abstract: The present invention provides catalysts, methods, and reactor systems for converting oxygenated hydrocarbons to oxygenated compounds. The invention includes methods for producing cyclic ethers, monooxygenates, dioxygenates, ketones, aldehydes, carboxylic acids, and alcohols from oxygenated hydrocarbons, such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like, using catalysts containing palladium, molybdenum, tin, and tungsten. The oxygenated compounds produced are useful in the production of liquid fuels, chemicals, and other products.Type: ApplicationFiled: December 30, 2014Publication date: May 21, 2015Inventors: Brian Blank, Randy Cortright, Taylor Beck, Elizabeth Woods, Mike Jehring
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Publication number: 20150141465Abstract: Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.Type: ApplicationFiled: November 14, 2014Publication date: May 21, 2015Inventors: Calvin W. YEE, Zhe Li
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Publication number: 20150112035Abstract: The present invention relates to a polymerizable liquid crystal compound, a liquid crystal composition including the same, and an optically anisotropic body. The polymerizable liquid crystal compound according to the present invention has not only large solubility in various solvents but also high birefringence and excellent coating orientation, and thus it can provide an optically anisotropic body which is thin but superior in optical properties.Type: ApplicationFiled: June 11, 2013Publication date: April 23, 2015Inventors: Kyung Chang Seo, Sung-Ho Chun, Dai Seung Choi, Mi-Ra Hong, Hyeong Bin Jang
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Patent number: 8980586Abstract: An object of the present invention is to provide a novel compound useful as an antifungal substance and a method for producing the compound.Type: GrantFiled: October 22, 2012Date of Patent: March 17, 2015Assignees: The Ritsumeikan Trust, National University Corporation Shizuoka UniversityInventors: Nobutaka Imamura, Kazuya Nakagawa, Shinji Tokuyama
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Publication number: 20150069297Abstract: A liquid crystal compound having high stability to heat and light, etc., a high clearing point, a low minimum temperature of liquid crystal phase, a low viscosity, a suitable optical anisotropy, a large dielectric anisotropy, a suitable elastic constant, and good compatibility with other liquid crystal compounds, a liquid crystal composition containing the compound, and a LCD element using the composition are described. The compound is represented by formula (1): wherein, for example, R1 is C1-10 alkyl, ring A1, ring A2, ring A3, ring A4 and ring B1 are independently 1,4-cyclohexylene, 1,4-phenylene, 1,4-phenylene in which at least one hydrogen is substituted with halogen, 1,3-dioxane-2,5-diyl, or tetrahydropyran-2,5-diyl, Z1, Z2, Z3 and Z4 are single bonds, l, m, n and o are independently 0 or 1, and l+m+n+o?1.Type: ApplicationFiled: February 7, 2013Publication date: March 12, 2015Inventor: Hiroyuki Tanaka
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Patent number: 8946458Abstract: The present invention provides catalysts, methods, and reactor systems for converting oxygenated hydrocarbons to oxygenated compounds. The invention includes methods for producing cyclic ethers, monooxygenates, dioxygenates, ketones, aldehydes, carboxylic acids, and alcohols from oxygenated hydrocarbons, such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like, using catalysts containing palladium, molybdenum, tin, and tungsten. The oxygenated compounds produced are useful in the production of liquid fuels, chemicals, and other products.Type: GrantFiled: August 15, 2012Date of Patent: February 3, 2015Assignee: Virent, Inc.Inventors: Brian Blank, Randy Cortright, Taylor Beck, Elizabeth Woods, Mike Jehring
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Publication number: 20150010469Abstract: Compounds having a structure of Formula I: or a pharmaceutically acceptable salt, tautomer, stereoisomer or deuterated analogue thereof, wherein X, R, R1, R2, R3, R4, M1, M2, L1, L2, J1, J2, a1, a2, b1 and b2 are as defined herein, are provided. Uses of such compounds for treatment of various indications, including prostate cancer as well as methods of treatment involving such compounds are also provided.Type: ApplicationFiled: July 3, 2014Publication date: January 8, 2015Applicants: British Columbia Cancer Agency Branch, University of British ColumbiaInventors: Raymond John Andersen, Javier Garcia Fernandez, Marianne Dorothy Sadar
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Patent number: 8912348Abstract: To provide a tetrahydropyranyl compound represented by General Formula (1) below: General Formula (1) where X denotes any one of a substituted or unsubstituted alkyl group, an oxygen atom, and a substituted or unsubstituted aromatic hydrocarbon group, R1, R2, R3, R4, R5 and R6 each denote any one of a hydrogen atom, a methyl group and an ethyl group, and n denotes an integer of 1 to 4.Type: GrantFiled: June 14, 2011Date of Patent: December 16, 2014Assignee: Ricoh Company, Ltd.Inventor: Yuuji Tanaka
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Publication number: 20140309438Abstract: An object of the present invention is to provide a novel compound useful as an antifungal substance and a method for producing the compound.Type: ApplicationFiled: October 22, 2012Publication date: October 16, 2014Applicants: THE RITSUMEIKAN TRUST, NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITYInventors: Nobutaka Imamura, Kazuya Nakagawa, Shinji Tokuyama
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Patent number: 8846751Abstract: This invention provides an agent for inhibiting production of hepatitis C virus with notable anti-HCV activity and without side-effects. The agent comprises a proanthocyanidin polymer composition illustrated in the following the general formula (1), wherein R1 is hydrogen or hydroxyl, R2 is hydroxyl, R3 is hydrogen when R1 is either hydrogen or hydroxyl, but R3 is possibly hydroxyl when R1 is either hydrogen or hydroxyl to the extent that both R1 and R3 being hydroxyl is at most 40 percents in the proanthocyanidin polymer composition said units of flavan-3-ol being bonded each other in any one of three patterns as follows; (i) a bond between carbon at the position 4 and carbon at the position 8, (ii) a bond between carbon at the position 4 and carbon at the position 6, (iii) a bond between carbon at the position 4 and carbon at the position 8, and between carbon, at the position 2 and oxygen at the position 7.Type: GrantFiled: August 5, 2011Date of Patent: September 30, 2014Assignees: Miyazaki Enterprise Promotion Organization, Miyazaki Prefecture, Unkai Shuzo Co., Ltd., Minami Nippon Dairy Co-Op Co., Ltd.Inventors: Masahiko Takeshita, Hirohito Tsubouchi, Hirofumi Uto, Hiroaki Kataoka, Takanori Kai, Hideaki Hirabaru, Miho Sakai, Ena Akamatsu
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Patent number: 8791254Abstract: A hydrofluoroether compound comprises at least one five- or six-membered, perfluorinated heterocyclic ring, each ring comprising four or five ring carbon atoms and one or two catenated heteroatoms selected from divalent ether oxygen atoms and trivalent nitrogen atoms, at least one of the catenated heteroatoms being a divalent ether oxygen atom, and each of the ring carbon atoms adjacent to the divalent ether oxygen atom bearing a fluorochemical group that comprises a tetrafluoroethylidene moiety (—(CF3)CF—) that is directly bonded to the ring carbon atom, the fluorochemical group optionally comprising at least one catenated heteroatom selected from divalent ether oxygen atoms and trivalent nitrogen atoms.Type: GrantFiled: December 6, 2006Date of Patent: July 29, 2014Assignee: 3M Innovative Properties CompanyInventors: Daniel R. Vitcak, Richard M. Flynn, Michael G. Costello
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Patent number: 8748484Abstract: An anti-cancer ruthenium complex containing organometallic triruthenium with two maltol ligands is claimed.Type: GrantFiled: April 9, 2012Date of Patent: June 10, 2014Assignee: Research Foundation of The City University of New YorkInventor: Varattur Dayal Reddy
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Publication number: 20140134193Abstract: The present invention is directed to novel cytotoxic spliceostatin analogs and derivatives, to antibody drug conjugates thereof, and to methods for using the same to treat medical conditions including cancer.Type: ApplicationFiled: October 31, 2013Publication date: May 15, 2014Applicant: PFIZER INC.Inventors: Chakrapani SUBRAMANYAM, Frank Erich KOEHN, Kenneth John DIRICO, Alessandra S. EUSTAQUIO, Michael Eric GREEN, Haiyin HE, Min HE, Christopher John O'DONNELL, Sujiet PUTHENVEETIL, Anokha RATNAYAKE, Jesse Alexander TESKE, Hui Yu YANG
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Publication number: 20140088079Abstract: The present invention relates to a compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes. The present invention also provides a method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound.Type: ApplicationFiled: June 1, 2012Publication date: March 27, 2014Applicant: GREEN CROSS CORPORATIONInventors: Soongyu Choi, Kwang Seop Song, Suk Ho Lee, Min Ju Kim, Hee Jeong Seo, Eun-Jung Park, Younggyu Kong, So Ok Park, Hyunku Kang, Myung Eun Jung, Kinam Lee, Hyun Jung Kim, Jun Sung Lee, Min Woo Lee, Mi-Soon KIM, Dong Ho Hong, Misuk Kang
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Publication number: 20140073501Abstract: A species of Burkholderia sp with no known pathogenicity to vertebrates but with pesticidal activity (e.g., plants, insects, fungi, weeds and nematodes) is provided. Also provided are natural products derived from a culture of said species and methods of controlling pests using said natural products.Type: ApplicationFiled: March 15, 2013Publication date: March 13, 2014Inventors: Ratnakar Asolkar, Marja Koivunen, Pamela Marrone
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Publication number: 20140051872Abstract: The present invention provides catalysts, methods, and reactor systems for converting oxygenated hydrocarbons to oxygenated compounds. The invention includes methods for producing cyclic ethers, monooxygenates, dioxygenates, ketones, aldehydes, carboxylic acids, and alcohols from oxygenated hydrocarbons, such as carbohydrates, sugars, sugar alcohols, sugar degradation products, and the like, using catalysts containing palladium, molybdenum, tin, and tungsten. The oxygenated compounds produced are useful in the production of liquid fuels, chemicals, and other products.Type: ApplicationFiled: August 15, 2012Publication date: February 20, 2014Applicant: Virent, Inc.Inventors: Brian Blank, Randy Cortright, Taylor Beck, Elizabeth Woods, Mike Jehring
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Publication number: 20140028964Abstract: The invention relates to a liquid-crystalline medium which comprises at least one compound of the formula I, in which R1, R1*, rings A and B, Z1, L1, L2, a and b have the meanings indicated in Claim 1, and to the use thereof for an active-matrix display, in particular based on the VA, PSA, PS-VA, PALC, FFS, PS-FFS, IPS or PS-IPS effect.Type: ApplicationFiled: March 8, 2012Publication date: January 30, 2014Applicant: MERCK PATENT GMBHInventors: Melanie Klasen-Memmer, Achim Goetz, Georg Bernatz
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Patent number: 8628685Abstract: Compounds including at least one mesogenic substructure and at least one long flexible segment and methods of synthesizing the same are disclosed. Formulations which include various embodiments of the mesogen-containing compounds and their use in articles of manufacture and ophthalmic devices are also disclosed.Type: GrantFiled: March 18, 2011Date of Patent: January 14, 2014Assignee: Transitions Optical, IncInventors: Meng He, Anil Kumar
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Publication number: 20140010763Abstract: Novel fluorogenic compounds designed such that upon a chemical event, compounds capable of emitting NIR light are generated, are disclosed. The compounds comprise two or more acceptor-containing moieties and a cleavable donor-containing moiety, being in complete pi-electrons conjugation and being such that no delocalization of pi-electrons is enabled. Also disclosed are fluorescent compounds generated upon subjecting the fluorogenic compounds to a chemical event (e.g., deprotonation). Also disclosed are uses of the fluorogenic compounds as NIR probed with a Turn-ON mechanism in monitoring presence and/or level of various analytes.Type: ApplicationFiled: September 15, 2013Publication date: January 9, 2014Applicant: Ramot at Tel-Aviv University Ltd.Inventors: Doron SHABAT, Ronit Satchi-Fainaro
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Patent number: 8623238Abstract: The present invention relates to compounds represented by the following Formula Ic, in which R2-R6 can each independently be selected from hydrogen or hydrocarbyl (e.g., methyl); L1 and L4 are each independently a divalent linking group, such as a bond or —OC(O)—R8—C(O)O—, where R8 can be divalent hydrocarbyl (e.g., —CH2CH2—); each L2 and each L5 each independently represent a flexible segment, such as divalent linear or branched C1-C25 alkyl; each L3 and each L6 each independently represent a rigid segment including, for example, optionally substituted phenylen-1,4-diyl groups; t and s are each independently from 1 to 4; m and p are each independently from 0 to 4 for each t, provided that the sum of m and p is at least 1 for each t; q and r are each independently from 0 to 4 for each s, provided that the sum of q and r is at least 1 for each s; and E1 and E2 can each independently be hydrogen or hydrocarbyl.Type: GrantFiled: August 8, 2011Date of Patent: January 7, 2014Assignee: Transitions Optical, Inc.Inventors: Ruisong Xu, Xiao-Man Dai, Anil Kumar, Meng He, Chenguang Li, Rachael L. Yoest
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Publication number: 20130271719Abstract: To provide a liquid crystal compound having a large positive value of dielectric anisotropy and a small viscosity. The compound is represented by formula (1): wherein, in formula (1), R1 is alkyl having 1 to 20 carbons or the like; ring A1 is 1,4-cyclohexylene or the like; ring A2 is 1,4-phenylene, 2-fluoro-1,4-phenylene, 2,6-difluoro-1,4-phenylene or the like; ring A3 is 1,4-cyclohexylene, 1,4-phenylene, 2-fluoro-1,4-phenylene, 2,6-difluoro-1,4-phenylene or the like; and X1 is halogen, alkyl having 1 to 10 carbons or the like, and in the alkyl, at least one of hydrogen may be replaced by halogen.Type: ApplicationFiled: April 4, 2013Publication date: October 17, 2013Applicants: JNC PETROCHEMICAL CORPORATION, JNC CORPORATIONInventors: Takahiro KUBO, Yasuyuki GOTOH
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Patent number: 8431039Abstract: The present invention relates to compounds represented by the following Formula Ia, in which each R1-R6 can in each case be independently selected from hydrogen or hydrocarbyl (e.g., methyl); R7 is a multivalent linking group, such as L1 is a divalent linking group, such as a bond or divalent optionally substituted hydrocarbyl; each L2 independently represents a flexible segment, such as divalent linear or branched C1-C25 alkyl; each L3 independently represents a rigid segment including, for example, optionally substituted phenylen-1,4-diyl groups; t is from 1 to 4; m and p are each independently from 0 to 4 for each t, provided that the sum of m and p is at least 1 for each t; and E can be hydrogen or optionally substituted hydrocarbyl. The present invention also relates to compositions, such as liquid crystal compositions, and articles, such as optical elements, that include the compound represented by Formula Ia.Type: GrantFiled: August 8, 2011Date of Patent: April 30, 2013Assignee: Transitions Optical, Inc.Inventors: Xiao-Man Dai, Ruisong Xu, Meng He, Anil Kumar, Rachael L. Yoest, Chenguang Li
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Patent number: 8389073Abstract: The invention provides a liquid crystal compound that has a large negative dielectric anisotropy (??) and also has at least one of characteristics such as the stability to heat, light or the like, a high clearing point, a suitable refractive index anisotropy (?n), a large negative dielectric anisotropy (??) and an excellent compatibility with other liquid crystal compounds. An excellent effect in which especially the value of the dielectric anisotropy (??) is increased negatively is achieved by use of the compound having two moieties of 1) a tetrahydropyran ring and and thus the effect is utilized.Type: GrantFiled: February 1, 2010Date of Patent: March 5, 2013Assignees: JNC Corporation, JNC Petrochemical CorporationInventors: Kenji Hirata, Tokifumi Masukawa, Junichi Yamashita, Maiko Ito
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Patent number: 8383931Abstract: The present invention relates to substrates coated with films comprising compounds of general formula (I) below: and also to the process for manufacturing them and to their use as anode interface layer in electronic devices. The present invention also relates to organic electroluminescent diodes (OLED), polymeric electroluminescent diodes (PLED), organic field-effect transistors (OFET) and organic solar cells (OSC) comprising a substrate according to the invention, to specific organic solar cells and to the process for manufacturing them. Compounds of formula (I) as such also form part of the invention.Type: GrantFiled: October 13, 2009Date of Patent: February 26, 2013Assignees: Commissariat a l'Energie Atomique, Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie (Paris 6)Inventors: Denis Fichou, Stéphane Berny, Ludovic Tortech
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Patent number: 8349210Abstract: The present invention relates to compounds represented by the following Formula I, in which R1-R6 can each independently be selected from hydrogen or hydrocarbyl (e.g., methyl); L1 is a divalent linking group, such as a bond or —OC(O)—R8—C(O)O—, where R8 can be divalent hydrocarbyl (e.g., —CH2CH2—); each L2 independently represents a flexible segment, such as divalent linear or branched C1-C25 alkyl; each L3 independently represents a rigid segment including, for example, optionally substituted phenylen-1,4-diyl groups; t is from 1 to 4; m and p are each independently from 0 to 4 for each t, provided that the sum of m and p is at least 1 for each t; and E can be hydrogen or hydrocarbyl. The present invention also relates to compositions, such as liquid crystal compositions, and articles, such as optical elements, that include the compound represented by Formula I.Type: GrantFiled: August 8, 2011Date of Patent: January 8, 2013Assignee: Transitions Optical, Inc.Inventors: Ruisong Xu, Xiao-Man Dai, Anil Kumar, Meng He, Chenguang Li, Rachael L. Yoest
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Publication number: 20120301177Abstract: An electrophotographic photosensitive member that includes the outermost surface layer formed by curing a mixture of a charge transporting substance having a chain-polymerizable functional group and a urea compound represented by the following formula (1) or (2), and a process cartridge and an electrophotographic apparatus each including the electrophotographic photosensitive member.Type: ApplicationFiled: May 22, 2012Publication date: November 29, 2012Applicant: CANON KABUSHIKI KAISHAInventors: Masato Tanaka, Masaki Nonaka
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Patent number: 8309599Abstract: The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.Type: GrantFiled: September 15, 2010Date of Patent: November 13, 2012Assignee: University of Pittsburgh-Of The Commonwealth System of Higher EducationInventors: Kazunori Koide, Brian J. Albert, Ananthapadmanabhan Sivaramakrishnan
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Publication number: 20120269771Abstract: The present invention discloses a new class of compounds that exhibit an inhibitory effect on influenza virus type A and B, which may or may not be resistant to other drugs, as well as on other types of viruses, such as flavivirus but also on protozoa and other micro-organisms, their preparation methods, pharmaceutical formulations containing them and their use as medicinal products for the treatment of various conditions caused by particular microorganisms, including viruses, bacteria and protozoa, which affect animal and human health.Type: ApplicationFiled: November 25, 2010Publication date: October 25, 2012Inventors: Paolo Alberto Veronesi, Pablo E.A. Rodriguez, Anna Maria Veronesi, Emanuela Peschechera
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Publication number: 20120213720Abstract: A prodrug composition for skin with twin protecting groups bound by disubstituted benzene is disclosed. The prodrug composition is a derivative of 1,4-bis(tetrahydro-2H-pyran-2-yloxy)benzene. Thereby, the twin protecting groups endow the prodrug composition with improved duration of action and efficiency to a targeted object such as melanocytes or tyrosinase, so as to facilitate distributing the prodrug composition over the stratum basale, in turn promoting melanocytes' absorption and tyrosinase's transportation as well as metabolism.Type: ApplicationFiled: February 23, 2011Publication date: August 23, 2012Inventor: Hungsen Lai
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Publication number: 20120165528Abstract: The present invention relates to chiral binaphthyl compounds having good solubility and high helical twisting power. The chiral binaphthyl compounds as dopants in the liquid crystal compositions can help enhance the display quality of the liquid crystal panels.Type: ApplicationFiled: April 27, 2011Publication date: June 28, 2012Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Jian-Wen Lin, Chun-Ming Wu, Shih-Hsien Liu, Kung-Lung Cheng
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Publication number: 20120145958Abstract: A compound represented by formula (1-1) or (1-2) is provided. For example, R1 and R2 are independently hydrogen, alkyl having 1 to 10 carbons or alkoxy having 1 to 9 carbons; the ring A1, the ring A2, the ring A3, the ring A4, the ring A5 and the ring A6 are independently 1,4-cyclohexylene or 1,4-phenylene; a, b, c, d, e and f are independently 0 or 1, and the sum of a, b, c, d, e and f is 2; and g, h, i, j, k and l are independently 0 or 1, and the sum of g, h, i, j, k and l is 2.Type: ApplicationFiled: August 10, 2010Publication date: June 14, 2012Applicants: JNC PETROCHEMICAL CORPORATION, JNC CORPORATIONInventors: Tokifumi Masukawa, Kenji Hirata, Junichi Yamashita
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Publication number: 20120142948Abstract: To provide a tetrahydropyranyl compound represented by General Formula (1) below: General Formula (1) where X denotes any one of a substituted or unsubstituted alkyl group, an oxygen atom, and a substituted or unsubstituted aromatic hydrocarbon group, R1, R2, R3, R4, R5 and R6 each denote any one of a hydrogen atom, a methyl group and an ethyl group, and n denotes an integer of 1 to 4.Type: ApplicationFiled: June 14, 2011Publication date: June 7, 2012Inventor: Yuuji Tanaka
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Patent number: 8163461Abstract: The invention provides various photoacid generator compounds and ionic components thereof. Photoresist compositions that include the ions and non-ionic photoacid generator compounds are also provided. The invention further provides methods of making and using the photoacid generator compounds and photoresist compositions disclosed herein. The compounds and compositions are useful as photoactive components in chemically amplified resist compositions for use in, for example, various microfabrication applications.Type: GrantFiled: April 9, 2009Date of Patent: April 24, 2012Assignee: Cornell Research Foundation, Inc.Inventors: Christopher K. Ober, Yi Yi
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Publication number: 20120035255Abstract: The present invention relates to compounds having general formula (I), i.e. poly-alkyl-bis-maltolic molecules and in particular to derivates of [(3-hydroxy-4-pyron-2-yl)methyl]-amine and pharmaceutically acceptable salts thereof, and to the use thereof as anti-neoplastic drugs, in particular, for the preparation of a medicament for the treatment of neoplastic diseases.Type: ApplicationFiled: November 27, 2009Publication date: February 9, 2012Applicant: Universita' Degli Studi Di UrbinoInventors: Mirco Fanelli, Vieri Fusi
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Publication number: 20110297881Abstract: The invention provides a liquid crystal compound that has a large negative dielectric anisotropy (??) and also has at least one of characteristics such as the stability to heat, light or the like, a high clearing point, a suitable refractive index anisotropy (?n), a large negative dielectric anisotropy (??) and an excellent compatibility with other liquid crystal compounds. An excellent effect in which especially the value of the dielectric anisotropy (??) is increased negatively is achieved by use of the compound having two moieties of 1) a tetrahydropyran ring and and thus the effect is utilized.Type: ApplicationFiled: February 1, 2010Publication date: December 8, 2011Applicants: CHISSO PETROCHEMICAL CORPORATION, JNC CORPORATIONInventors: Kenji Hirata, Tokifumi Masukawa, Junichi Yamashita, Maiko Ito
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Publication number: 20110277378Abstract: A process for liquefying a cellulosic material to produce a liquefied product from cellulosic material is provided. Products obtained from such process and use of such products to prepare biofuels is also provided.Type: ApplicationFiled: May 12, 2011Publication date: November 17, 2011Applicant: SHELL OIL COMPANYInventors: Klaas Lambertus VON HEBEL, Jean-Paul LANGE
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Publication number: 20110263428Abstract: Compounds of formula (I), wherein the substituents are as defined in claim 1, are suitable for use as herbicides.Type: ApplicationFiled: July 1, 2009Publication date: October 27, 2011Applicant: SYNGENTA CROP PROTECTION, INC.Inventors: Stephane Andre Marie Jeanmart, Russell Colin Viner, John Benjamin Taylor, William Guy Whittingham, Jeffrey Steven Wailes, Sarah Margaret Targett, Christopher John Mathews, Mangala Govenkar, Matthew Robert Cordingley, Claire Janet Russell, Melloney Tyte
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Patent number: 8043789Abstract: A photosensitive compound whose size is smaller than conventional polymer for photoresist, and which has well-defined (uniform) structure, and a photoresist composition including the same are disclosed. The photosensitive compound represented by the following formula. Also, the present invention provides a photoresist composition comprising 1 to 85 wt % (weight %) of the photosensitive compound; 0.05 to 15 weight parts of a photo-acid generator with respect to 100 weight parts of the photosensitive compound; and 10 to 5000 weight parts of an organic solvent. In the formula, n is 0 or 1, x is 1, 2, 3, 4 or 5, y is 2, 3, 4, 5 or 6, z is 0, 1, 2, 3 or 4, R, R? and R? are independently hydrocarbon group of 1 to 30 carbon atoms, preferably 2 to 20 carbon atoms, and R?? is a hydrogen atom or hydrocarbon group of 1 to 30 carbon atoms, preferably 2 to 20 carbon atoms.Type: GrantFiled: December 17, 2008Date of Patent: October 25, 2011Assignee: Dongjin Semichem Co., Ltd.Inventors: Jae-Woo Lee, Min-Ja Yoo, Jun-Gyeong Lee, Young-Bae Lim, Jae-Hyun Kim
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Publication number: 20110207604Abstract: A species of Burkholderia sp with no known pathogenicity to vertebrates but with pesticidal activity (e.g., plants, insects, fungi, weeds and nematodes) is provided. Also provided are natural products derived from a culture of said species and methods of controlling pests using said natural products.Type: ApplicationFiled: February 24, 2011Publication date: August 25, 2011Applicant: MARRONE BIO INNOVATIONSInventors: Ratnakar Asolkar, Marja Koivunen, Pamela Marrone, Ana-Lucia Cordova-Kreylos, Huazhang Huang
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Publication number: 20110200536Abstract: The present invention relates to chelators, in particular to chelators which are capable of forming complexes, i.e. paramagnetic chelates, with paramagnetic metal ions. The invention also relates to said paramagnetic chelates, said paramagnetic chelates linked to other molecules and their use as contrast agents in magnetic resonance imaging (MRI).Type: ApplicationFiled: August 12, 2008Publication date: August 18, 2011Inventors: Harry John Wadsworth, Ian Martin Newington, Dennis O'shea
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Publication number: 20110190349Abstract: The present invention relates to a compound of formula I wherein R1/R2 are independently from each other hydrogen, (CR2)o-cycloalkyl, optionally substituted by lower alkyl or hydroxy, or are lower alkyl or heterocycloalkyl, and o is 0 or 1; and R may be the same or different and is hydrogen or lower alkyl; or R1 and R2 may form together with the N atom to which they are attached a heterocycloalkyl group, selected from the group consisting of pyrrolidinyl, piperidinyl, 3-aza-bicyclo[3.1.0]hex-3-yl or 2-aza-bicyclo[3.1.Type: ApplicationFiled: January 21, 2011Publication date: August 4, 2011Inventors: Sabine Kolczewski, Emmanuel Pinard
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Patent number: 7985291Abstract: A perimidine-substituted squarylium dye is represented by the following formula (I):Type: GrantFiled: April 22, 2009Date of Patent: July 26, 2011Assignee: Fuji Xerox Co., Ltd.Inventors: Kazuhiko Hirokawa, Kazunori Anazawa, Yuka Ito, Minquan Tian, Suguru Nakaso, Shinji Hasegawa, Takashi Matsubara, Makoto Furuki, Miho Watanabe, Tomoko Miyahara
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Patent number: 7955664Abstract: The chroman compounds of the formula I according to the invention R1-(A1-Z1)a—W1—(Z2-A2)b-Z3—W2—(Z4-A3)c-R2 in which R1, A1, A2, A3, W1, W2, Z1, Z2, Z3, Z4, a, b and c have the meanings indicated in claim 1, have two moieties W1 and W2 derived from chroman. The compounds are suitable as components of anisotropic switching media, as used, for example, in liquid-crystal display devices.Type: GrantFiled: December 11, 2007Date of Patent: June 7, 2011Assignee: Merck Patent GesellschaftInventors: Andreas Taugerbeck, Alexander Hahn, Achim Goetz
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Publication number: 20110110865Abstract: The present invention relates to chelators, in particular to chelators which are capable of forming complexes, i.e. paramagnetic chelates, with paramagnetic metal ions. The invention also relates to said paramagnetic chelates, said paramagnetic chelates linked to other molecules and their use as contrast agents in magnetic resonance imaging (MRI).Type: ApplicationFiled: August 12, 2008Publication date: May 12, 2011Inventors: Oskar Axelsson, Horry John Wadsworth, Ian Martin Newington, Dennis O'Shea
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Publication number: 20110083730Abstract: The present invention relates to substrates coated with films comprising compounds of general formula (I) below: and also to the process for manufacturing them and to their use as anode interface layer in electronic devices. The present invention also relates to organic electroluminescent diodes (OLED), polymeric electroluminescent diodes (PLED), organic field-effect transistors (OFET) and organic solar cells (OSC) comprising a substrate according to the invention, to specific organic solar cells and to the process for manufacturing them. Compounds of formula (I) as such also form part of the invention.Type: ApplicationFiled: October 13, 2009Publication date: April 14, 2011Inventors: Denis Fichou, Stéphane Berny, Ludovic Tortech