Halogen Attached Indirectly To The Hetero Ring By Nonionic Bonding Patents (Class 549/563)
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Patent number: 9439294Abstract: Reaction products of heterocyclic nitrogen compounds, polyepoxide compounds and polyhalogen compounds may be used as levelers in metal electroplating baths, such as copper electroplating baths, to provide good throwing power. Such reaction products may plate metal with good surface properties and good physical reliability.Type: GrantFiled: April 16, 2014Date of Patent: September 6, 2016Inventors: Julia Kozhukh, Zuhra I. Niazimbetova
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Publication number: 20140243538Abstract: A pretreated titanium silicalite with MFI structure (TS-1) catalyst which has been pretreated with methanol, and then optionally filtered and optionally air-dried to form a pretreated activated TS-1 catalyst. The activated TS-1 may be used in an epoxidation reaction with no additional methanol added and has equivalent activity to TS-1 used with large excesses of methanol. By removing the need for additional methanol during the reaction, the losses of epichlorohydrin from solvolysis are minimized significantly.Type: ApplicationFiled: April 14, 2014Publication date: August 28, 2014Applicant: Dow Global Technologies, LLCInventor: Hannah L. Crampton
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Patent number: 8557500Abstract: The present invention provides a salt represented by the formula (I): wherein Q1 and Q2 independently each represent a fluorine atom or a C1-C6 perfluoroalkyl group, L1 represents a C1-C17 divalent saturated hydrocarbon group in which one or more —CH2— can be replaced by —O— or —CO—, L2 represents a single bond or a C1-C6 alkanediyl group in which one or more —CH2— can be replaced by —O— or —CO—, Y represents a C3-C18 alicyclic hydrocarbon group which can have one or more substituents, and one or more —CH2— in the alicyclic hydrocarbon group can be replaced by —O—, —CO— or —SO2—, and Z+ represents an organic counter ion.Type: GrantFiled: February 28, 2012Date of Patent: October 15, 2013Assignee: Sumitomo Chemical Company, LimitedInventors: Koji Ichikawa, Hiromu Sakamoto, Takahiro Yasue
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Publication number: 20130012731Abstract: A pretreated titanium silicalite with MFI structure (TS-1) catalyst which has been pretreated with methanol, and then optionally filtered and optionally air-dried to form a pretreated activated TS-1 catalyst. The activated TS-1 may be used in an epoxidation reaction with no additional methanol added and has equivalent activity to TS-1 used with large excesses of methanol. By removing the need for additional methanol during the reaction, the losses of epichlorohydrin from solvolysis are minimized significantly.Type: ApplicationFiled: March 22, 2011Publication date: January 10, 2013Applicant: DOW GLOBAL TECHNOLOGIES LLCInventor: Hannah L. Crampton
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Publication number: 20120316353Abstract: The present invention provides one or more embodiments of a process for the epoxidation of an olefin. For the embodiments, the process includes reacting the olefin, with the proviso that the olefin is not propylene, with a hydrogen peroxide solution at a predetermined pH in the presence of a catalyst and a solvent at a predetermined reaction temperature. The pH of the hydrogen peroxide solution is adjusted to the predetermined pH by contacting the hydrogen peroxide solution with a supported base to remove acidic species from the hydrogen peroxide solution.Type: ApplicationFiled: November 12, 2010Publication date: December 13, 2012Inventor: Hannah L. Crampton
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Patent number: 8318959Abstract: The method of preparing novel allyl ethers. Novel glycidyl ethers and their preparation. Polyfunctional poly(glycidyl ethers) their methods of preparation. Novel polyurethanes based on the polyfunctional glycidyl ethers and their method of preparation.Type: GrantFiled: January 4, 2012Date of Patent: November 27, 2012Assignee: Flurochem, Inc.Inventors: Kurt Baum, Wen-Huey Lin
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Publication number: 20120238762Abstract: To provide an azole derivative which is contained as an active ingredient in an agro-horticultural agent having an excellent controlling effect on diseases. An azole derivative according to the invention is represented by Formula (I), wherein R1 and R2 are same or different, and each denotes a substituted C3-C6 cycloalkyl group or a C1-C4 alkyl group substituted with the substituted C3-C6 cycloalkyl group; and A denotes a nitrogen atom or a methyne group.Type: ApplicationFiled: November 29, 2010Publication date: September 20, 2012Applicant: KUREHA CORPORATIONInventors: Keiichi Sudo, Takashi Shimokawara, Eiyu Imai, Nobuyuki Kusano, Hisashi Kanno, Taiji Miyake, Masaru Mori, Toshihide Saishoji
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Publication number: 20120136167Abstract: This invention relates to processes for the production of optically active 2-(disubstituted aryl)cyclopropylamine compounds and optically active 2-(disubstituted aryl) cyclopropane carboxamide compounds which are useful intermediates for the preparation of pharmaceutical agents, and in particular the compound [1S-(1?,2?,3?(1S*,2R*),5?]-3-[7-[2-(3,4-difluorophenyl)-cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)-cyclopentane-1,2-diol.Type: ApplicationFiled: August 26, 2011Publication date: May 31, 2012Applicant: ASTRAZENECA ABInventors: Masaru Mitsuda, Tadashi Moroshima, Kentaro Tsukuya, Kazuhiko Watabe, Masahiko Yamada
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Publication number: 20120130095Abstract: A multiple liquid phase composition and process for preparing an oxirane product, such as epichlorohydrin, including a reaction mixture of: (a) at least one olefin, wherein the olefin is selected from one of (i) an aliphatic olefin or substituted aliphatic olefin, with the proviso that the aliphatic olefin is not propylene, (ii) a cycloaliphatic olefin, (iii) an aromatic olefin, (iv) a cycloaromatic olefin, and (v) mixtures thereof; (b) at least one peroxide compound, (c) at least one catalyst, and (d) and a solvent mixture; wherein the solvent mixture comprises at least (i) at least one alcohol or a combination of alcohols, and (ii) at least one non-reactive co-solvent; wherein the solvents are mixed at a predetermined concentration; wherein the non-reactive co-solvent has a different boiling point than the oxirane product; and wherein the oxirane product partitions into a high affinity solvent during the reaction.Type: ApplicationFiled: August 4, 2010Publication date: May 24, 2012Inventors: Hannah L. Crampton, Philip J. Carlberg, David H. West, Bruce D. Hook, William W. Fan, Anna Forlin
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Publication number: 20110137056Abstract: The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceuticals. In particular, the present invention concerns enantiomerically pure trans-cyclopropane carboxylic acid derivatives, processes for preparing the carboxylic acid derivatives and their use in preparing pharmaceuticals.Type: ApplicationFiled: November 30, 2010Publication date: June 9, 2011Applicant: ASTRAZENECA ABInventors: Jean-Paul Dejonghe, Koen Peeters, Marc Renard
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Publication number: 20110091508Abstract: The invention features oligofluorinated cross-linked polymers and their use in the manufacture of articles and coating surfaces.Type: ApplicationFiled: October 2, 2008Publication date: April 21, 2011Applicant: Interface Biologics ,Inc.Inventors: Roseita Esfand, J. Paul Santerre, Mark J. Ernsting, H. Hung Pham, Vivian Z. Wang, Meilin Yang
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Publication number: 20110028683Abstract: A composition comprising glycerol and at least one cyclic oligomer of glycerol, a process for obtaining the composition, and its use in the manufacture of dichloropropanol and of derived products such as epichlorohydrin and epoxy resins.Type: ApplicationFiled: March 31, 2009Publication date: February 3, 2011Applicant: SOLVAY S.A.Inventors: Patrick Gilbeau, Bruno Jestin
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Patent number: 7863469Abstract: The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceuticals. In particular, the present invention concerns enantiomerically pure trans-cyclopropane carboxylic acid derivatives, processes for preparing the carboxylic acid derivatives and their use in preparing pharmaceuticals.Type: GrantFiled: August 3, 2007Date of Patent: January 4, 2011Assignee: AstraZeneca ABInventors: Jean-Paul Dejonghe, Koen Peeters, Marc Renard
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Publication number: 20100317515Abstract: The present invention relates to triazolylmethyloxiranes of the formula I in which the variables A, B and D have the meanings described in the claims and the description.Type: ApplicationFiled: December 12, 2008Publication date: December 16, 2010Applicant: BASF SEInventors: Jochen Dietz, Thomas Grote, Bernd Mueller, Jan Klaas Lohmann, Jens Renner, Sarah Ulmschneider, Alice Glaettli, Marianna Vrettou
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Publication number: 20100311581Abstract: The present invention relates to triazolylmethyloxiranes of the formula I in which the variables D and B have the meanings as defined in the description and the claims.Type: ApplicationFiled: December 15, 2008Publication date: December 9, 2010Applicant: BASF SEInventors: Jochen Dietz, Thomas Grote, Bernd Mueller, Jan Klaas Lohmann, Jens Renner, Sarah Ulmschneider, Alice Glaettli, Marianna Vrettou
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Publication number: 20100273651Abstract: The present invention relates to azolylmethyloxiranes of the formula I in which the variables A, B and D have the meanings as defined in the description and the claims.Type: ApplicationFiled: December 15, 2008Publication date: October 28, 2010Applicant: BASF SEInventors: Jochen Dietz, Thomas Grote, Bernd Mueller, Jan Klaas Lohmann, Jens Renner, Sarah Ulmschneider, Alice Glaettli, Marianna Vrettou
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Publication number: 20100179302Abstract: Manufacture of dichloropropanol Process for manufacturing dichloropropanol wherein a glycerol-based product comprising at least one diol containing at least 3 carbon atoms other than 1,2-propanediol, is reacted with a chlorinating agent, and of products derived from dichloropropanol such as epichlorohydrin and epoxy resins. No figure.Type: ApplicationFiled: June 20, 2008Publication date: July 15, 2010Applicant: SOLVAY (SOCIETE ANONYME)Inventors: Philippe Krafft, Patrick Gilbeau
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Patent number: 7557227Abstract: A process for producing hexafluoropropylene oxide, which comprises contacting a reaction product containing hexafluoropropylene oxide obtained by reacting hexafluoropropylene with oxygen, with at least one adsorbent selected from activated carbon and the following metal oxides, wherein the metal oxides are oxides of at least one metal selected from Groups 1 and 2 of the Periodic Table, Zr and Si.Type: GrantFiled: February 12, 2004Date of Patent: July 7, 2009Assignee: Asahi Glass Company, LimitedInventors: Hirokazu Takagi, Kazuya Oharu, Keiichi Ohnishi
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Publication number: 20080312440Abstract: The present invention relates to drug derivatives and linkers. The invention specifically relates to compounds and methods of phosphonates and linkers, that are useful as carriers for imaging agents and useful in the treatment of various bone diseases.Type: ApplicationFiled: April 16, 2008Publication date: December 18, 2008Applicant: University of Southern CaliforniaInventors: Charles E. McKenna, Boris A. Kashemirov, Joy Lynn F. Bala
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Publication number: 20080132719Abstract: The present invention relates to compounds useful as pharmaceutical intermediates, to processes for preparing the intermediates, to intermediates used in the processes, and to the use of the intermediates in the preparation of pharmaceuticals. In particular, the present invention concerns enantiomerically pure trans-cyclopropane carboxylic acid derivatives, processes for preparing the carboxylic acid derivatives and their use in preparing pharmaceuticals.Type: ApplicationFiled: August 3, 2007Publication date: June 5, 2008Applicant: ASTRAZENECA ABInventors: Jean-Paul Dejonghe, Koen Peeters, Marc Renard
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Patent number: 7195719Abstract: The invention relates to chiral nonracemic liquid crystal compounds having achiral tails comprising a perfluoroalkyl terminal portion which are useful as components in liquid crystal to impart high polarization to the mixture. The materials of this invention can be combined with known liquid crystal host materials to impart improved properties. Chiral nonracemic compounds of this invention can function as additives or dopants in host materials to impart chirality into an LC material.Type: GrantFiled: January 3, 2002Date of Patent: March 27, 2007Assignee: Displaytech, Inc.Inventors: Michael Wand, Xin Hua Chen, William N. Thurmes
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Patent number: 6849750Abstract: Disclosed are intermediates and processes for preparing epoxides of the formula: where R and PROT are defined herein. These epoxides are useful as intermediates in the production of biologically active compounds, i.e., in the production of pharmaceutical agents.Type: GrantFiled: April 23, 2002Date of Patent: February 1, 2005Assignee: Pharmacia & UpJohn Company LLCInventor: Michael R. Reeder
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Publication number: 20040249177Abstract: Compounds that function to provide level or uniform metal deposits are provided. These compounds are particularly useful in providing level copper deposits. Copper plating baths and methods of copper plating using these compounds are also provided. These baths and methods are useful for providing a planarized layer of copper on a substrate having small apertures. The compositions and methods provide complete fill of small apertures with reduced void formation.Type: ApplicationFiled: June 4, 2003Publication date: December 9, 2004Applicant: Shipley Company, L.L.C.Inventors: Deyan Wang, Chunyi Wu, Robert D. Mikkola
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Patent number: 6750250Abstract: 11,12-Oxidoarachidonic acid derivatives and methods of their use for treating dry eye are disclosed.Type: GrantFiled: June 12, 2002Date of Patent: June 15, 2004Assignee: Alcon, Inc.Inventors: David B. Belanger, Peter G. Klimko
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Patent number: 6670474Abstract: The present invention relates to novel epoxides having the formulas where Y is a CO, CO2 or SO2, AR is the same or different divalent unsubstituted or substituted aromatic, halogen-substituted aromatic or cyano-substituted aromatic hydrocarbon radical having from 6 to 20 carbon atoms, Z is a divalent hydrocarbon or ether radical having from 1 to 20 carbon atoms, including Y-Z-Y being CO, and R* is an alkyl, aryl, arylalkyl, alkoxy, aryloxy or arylalkoxy radical having from 0-20 carbon atoms. The epoxides of the present invention are useful in the formation of epoxy resins.Type: GrantFiled: March 11, 2002Date of Patent: December 30, 2003Inventor: R. Garth Pews
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Patent number: 6653419Abstract: A method for producing partially fluorinated epoxides and corresponding polyether homopolymers of these polyfluorinated epoxides is described. Also described is a method for incorporating a fluoroalcohol functional group into a polymer as a pendant group. Certain perfluorinated olefins are also described. These polyfluorinated epoxides and the associated polymers and methods relating to them are useful components in photoresists, particulary in lithographic photoresists for use at low ultraviolet wavelengths (e.g., 157 nm).Type: GrantFiled: October 3, 2001Date of Patent: November 25, 2003Assignee: E. .I du Pont de Nemours and CompanyInventors: Viacheslav Alexandrovich Petrov, Andrew Edward Fiering, Jerald Feldman
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Patent number: 6538142Abstract: A process for the preparation of 5-(3,5-dimethylphenoxymethyl)-2-oxazolidinone, which includes: a) reacting 3,5-dimethylphonel with epichlorohydrin to obtain a mixture of 1-(3,5-dimethylphenoxy)2,3-epoxy propane (1) and 1-(3,5-dimethylphenoxy)-3-chloro-2-propanol (2); b) reacting the mixture of (1) and (2) obtained from step (a) with benzylamine to obtain a first compound; c) reducing the first compound with hydrogen in presence of ammonia, to obtain a second compound; and d) reacting the second compound with dimethylcarbonate in the presence of a strong base to obtain 5-(3,5-dimethlphenoxymethyl)-2-oxazolidinone.Type: GrantFiled: April 18, 2002Date of Patent: March 25, 2003Assignee: Farchemia S.r.l.Inventors: Gabriele Breviglieri, Sergio Contrini, Giacomo Bruno, Cinzia Assanelli
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Patent number: 6441121Abstract: A curable composition comprises a compound having at least one epoxy group and at least one styrenic or cinnamyl group per molecule.Type: GrantFiled: September 28, 2001Date of Patent: August 27, 2002Assignee: National Starch and Chemical Investment Holding CorporationInventors: Osama M. Musa, Harry Richard Kuder
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Method for making unsymmetrically substituted fluorenyl compounds for nonlinear optical applications
Patent number: 6379590Abstract: A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of a compound of the formula D wherein A′ is selected from the group consisting of —Br, —Cl, —F, —NO2, and —CN; A is selected from the group consisting of —NO2, —CN, —CO2R, —C(O)R, —SO2R, —SO2RF, —C(CN)═C(CN)2 and —CH═C(CN)2; RF is —CpF2p+1, p=from about 0 to about 10; R is an straight, branched or cyclic aliphatic alkyl group having about 1 to 10 carbon atoms, or an aromatic group such as phenyl or naphthyl; and is a carbonyl or a protected carbonyl such as a ketal or thio-ketal such as wherein R′ is —CrH2r+1; R″ is —(CH2)r—; and r is independently 2 or 3, with a nucleophilic reagent in the presence of an aprotic solventType: GrantFiled: December 2, 1994Date of Patent: April 30, 2002Assignee: AlliedSignal Inc.Inventors: Chengjiu Wu, Jianhui Shan -
Patent number: 6376662Abstract: A method for synthesizing C-glycosides of ulosonic acids such as Neu5Ac, by which diastereocontrolled synthesis of &agr;-C-glycosides of ulosonic acids is attained is disclosed. In the method of the present invention, an ulosonic acid sulfone or phosphite is reacted with an aldehyde or ketone compound in the presence of a lanthanide metal halide.Type: GrantFiled: November 17, 1998Date of Patent: April 23, 2002Assignee: University of Iowa Research FoundationInventors: Robert J. Linhardt, Iontcho R. Vlahov
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Patent number: 6177577Abstract: This invention relates to novel dicationic and polycationic monoprimary alcohol compounds and their derivatives, represented by the formula wherein each alk is independently alkyl of 1-8 carbon atoms; each ALK is independently alkyl of 1-8 carbon atoms; each R1, R2, R3, R4 or R5 is independently H or alkyl of 1-8 carbon atoms; n is 2-5; G is H, CR1R2CR3OHCR4R5X or X is Cl, Br or I; An− is an anion and p is 1-10; provided that the compound is soluble in water.Type: GrantFiled: November 15, 1991Date of Patent: January 23, 2001Assignee: The Dow Chemical CompanyInventors: Dorothy L. Roerden, R. Keith Frank
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Patent number: 6147224Abstract: Compounds of Formula 1, Formula 2 or Formula 3 where X is O, S, or (CR.sub.1 R.sub.1).sub.n where n is 0, 1 or 2; Y is a bivalent radical having Formula 4 or Formula 5 where o is an integer from 1 to 4 ##STR1## or Y is a bivalent aryl or 5 or 6 membered heteroaryl radical having 1 to 3 heteroatoms selected from N, S and O, said aryl or heteroaryl groups being unsubstituted, or substituted with 1 to 3 C.sub.1-6 alkyl or with 1 to 3 C.sub.1-6 fluoroalkyl groups; and the remaining symbols have the meaning described in the specification, have RXR selective retinoid agonist-like activity.Type: GrantFiled: October 1, 1998Date of Patent: November 14, 2000Assignee: Allergan Sales, Inc.Inventors: Vidyasagar Vuligonda, Kwok Yin Tsang, Jayasree Vasudevan, Roshantha A. Chandraratna
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Patent number: 6083981Abstract: The present invention relates to compounds that are inhibitors of interleukin-1.beta. converting enzyme that have the Formula I, II, or III. ##STR1## This invention also relates to a method of treatment of stroke, inflammatory diseases, septic shock reperfusion injury, Alzheimer's disease, and shigellosis, and to a pharmaceutically acceptable composition that contains a compound that is an inhibitor of interleukin-1.beta. converting enzyme.Type: GrantFiled: April 9, 1999Date of Patent: July 4, 2000Assignee: Warner-Lambert CompanyInventors: Hamish John Allen, Kenneth Dale Brady, William Glen Harter, Elizabeth Ann Lunney, Mark Stephen Plummer, Tomi Sawyer, Aurash Shahripour, Nigel Walker
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Patent number: 5986150Abstract: To provide a fluorine-containing olefin represented, for example, by CH.sub.2 .dbd.CFCF.sub.2 --R.sub.f.sup.6 --(CH.sub.2).sub.k --X.sup.2 [wherein, X.sup.2 is ##STR1## R.sub.f.sup.6 is a fluorine-substituted fluorine-containing alkyl group having 1 to 40 carbon atoms or --OR.sub.f.sup.7 --(Rf.sup.7 is a fluorine-substituted fluorine-containing alkyl group having 1 to 40 carbon atoms or a fluorine-substituted fluorine-containing ether group having 3 to 50 carbon atoms), k is 0 or an integer of 1 to 6]; a fluorine-containing polymer with functional group which is prepared by polymerizing the above-mentioned olefin, has good affinity with various heat-resisting thermoplastic resins and is capable of forming homogeneous dispersion with the thermoplastic resin; and a thermoplastic resin composition comprising the above-mentioned fluorine-containing polymer with functional group and an aromatic polyester or the like as the heat-resisting thermoplastic resin.Type: GrantFiled: May 15, 1997Date of Patent: November 16, 1999Assignee: Daikin Industries, Ltd.Inventors: Takayuki Araki, Tetsuo Shimizu, Takafumi Yamato, Masahiro Kumegawa, Yoshihisa Yamamoto
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Patent number: 5945552Abstract: A compound having the formula: ##STR1## wherein: R is fluorine, hydrogen, an unsubstituted or substituted aliphatic or unsubstituted or substituted aromatic radical;R.sub.1 is an unsubstituted or substituted aliphatic radical, or unsubstituted or substituted aromatic radical; andR.sub.2 is hydrogen, an unsubstituted or substituted aliphatic radical, or unsubstituted or substituted aromatic radical.Type: GrantFiled: November 21, 1997Date of Patent: August 31, 1999Assignee: AlliedSignal Inc.Inventor: Michael Van Der Puy
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Patent number: 5914412Abstract: Epoxides containing a perfluorovinyl group, and polymers made therefrom by polymerization of the epoxy function are disclosed. Such epoxides form polymers and copolymers useful for coatings, adhesion control agents, surface modifiers and crosslinking agents.Type: GrantFiled: May 16, 1994Date of Patent: June 22, 1999Assignee: E. I. du Pont de Nemours and CompanyInventors: Ming-Hong Hung, Shlomo Rozen
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Patent number: 5814612Abstract: The present invention provides a purified retinoid compound characterized by a molecular mass of about 320 daltons and an atomic composition of C.sub.20 H.sub.32 O.sub.3. The present invention also provides a purified retinoid compound having the structure: ##STR1## wherein the configuration of the C7, C9, and C11 double bond independently is Z or E and the absolute configuration at C13 and C14 is independently R or S; wherein R1 is alkyl, alkyl halide, alcohol, ester, ether, aldehyde, ketone, carboxylic acid, carboxylic ester, acyl halide, amide, nitrile, or amine; R2 and R3 are independently hydroxyl, halide, alkoxy, ester, alkyl, alcohol, ether, aldehyde, ketone, carboxylic acid, carboxylic ester, nitrile, amine, azide, alkyl halide, acid halide, acid azide, or amide; or wherein R2 and R3, or R1 and R2 are replaced by a 13,14-oxirane or a 14,15-oxirane group, respectively.Type: GrantFiled: May 6, 1992Date of Patent: September 29, 1998Assignees: Sloan-Kettering Institute for Cancer Research, The Trustees of Columbia in the City of New YorkInventors: Jochen Buck, Ulrich Hammerling, Fadila Derguini, Koji Nakanishi
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Patent number: 5530149Abstract: New azolylmethyl-fluorocyclopropyl derivatives of the formula ##STR1## in which R represents ##STR2## and addition products thereof which acids or metal salts are very effective for combating fungi.New oxiranes of the formula ##STR3## in which R has the abovementioned meaning, are valuable intermediates for the preparation of compounds of the formula (I).Type: GrantFiled: June 5, 1995Date of Patent: June 25, 1996Assignee: Bayer AktiengesellschaftInventors: Jurgen Scherkenbeck, Thomas Himmler, Stefan Bohm, Hermann Hagemann, Klaus Stroech, Stefan Dutzmann, Heinz-Wilhelm Dehne, Gerd Hanssler
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Patent number: 5514818Abstract: A method of resolving a mixture of stereoisomers of an aliphatic epoxide containing two or less oxygen atoms is provided. The method comprises utilizing a polysaccharide or a derivative thereof as a resolving agent.Type: GrantFiled: February 10, 1995Date of Patent: May 7, 1996Assignee: Daicel Chemical Industries, Ltd.Inventor: Kozo Tachibana
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Patent number: 5380887Abstract: A diphenylsulfone derivative of the formula (I) ##STR1## which is highly safe and used for imparting storage stability to a colored image of thermal or heat sensitive recording material, wherein R.sup.1 represents lower alkenyl or aralkyl optionally substituted with halogen or lower alkyl, and R.sup.2 represents hydrogen or methyl, provided that R.sup.2 represents methyl when R.sup.1 represents unsubstituted benzyl.Type: GrantFiled: February 4, 1994Date of Patent: January 10, 1995Assignee: Nippon Soda Co., Ltd.Inventors: Takafumi Tohyama, Takehiro Sato, Kousaku Morita, Masaaki Uchikawa, Nobuyuki Hirai
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Patent number: 5354511Abstract: Compounds having non-linear optical activity of the general formula ##STR1## wherein D and A are electron donor and acceptor groups, respectively, R.sup.1 and R.sup.2 are aromatic bridging groups, X and Y are preferably groups capable of partaking in polymerization reactions are suitable for use in polymer-based light modulator devices.Type: GrantFiled: November 27, 1992Date of Patent: October 11, 1994Assignee: AlliedSignal Inc.Inventors: Chengjiu Wu, Jianhui Shan, Ajay Nahata
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Patent number: 5340788Abstract: Storing stabilizers for color image of heat sensitive recording materials, which are higher safe diphenylsulfone derivatives represented by general formula (I), and the heat sensitive recording materials using them. ##STR1## (Wherein, R.sup.1 is aralkyl or lower alkenyl which may be substituted with halogen or lower alkyl and R.sup.2 is hydrogen or methyl, but when R.sup.1 is unsubstituted benzyl, R.sub.2 is methyl).Type: GrantFiled: March 19, 1992Date of Patent: August 23, 1994Assignee: Nippon Soda Co., Ltd.Inventors: Takafumi Tohyama, Takehiro Sato, Kousaku Morita, Masaaki Uchikawa, Nobuyuki Hirai
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Patent number: 5288722Abstract: The present invention relates to a compound of the formula: ##STR1## wherein R.sup.1 is 2-methyl-1-propenyl group or isobutyl group; R.sup.2 and R.sup.3 are each hydrogen atom, an optionally substituted hydrocarbon residue or an optionally substituted acyl group or R.sup.2 and R.sup.3 may form a ring together with the adjacent nitrogen atom; and the bonding mark .about. represents an .alpha.-linkage or .beta.-linkage, or a salt thereof. The compound (I) of the present invention has, among others, angiogenesis inhibiting activity, cell-growth inhibiting activity and immune reaction inhibiting activity, thus being useful as medicines, etc.Type: GrantFiled: September 19, 1991Date of Patent: February 22, 1994Assignee: Takeda Chemical Industries, Ltd.Inventors: Shoji Kishimoto, Shogo Marui, Takeshi Fujita
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Patent number: 5288883Abstract: Fungicidal azolyl-propanols of the formula ##STR1## in which R represents halogenoalkyl, halogenoalkenyl, a 2-phenoxy-isopropyl radical, ##STR2## Y represents nitrogen or a CH group, Z represents halogen, alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, cyano, phenoxy, halophenoxy, or optionally substituted aryl,m represents the number 0, 1, 2, or 3,and addition products thereof with acids and metal salts.Type: GrantFiled: December 28, 1992Date of Patent: February 22, 1994Assignee: Bayer AktiengesellschaftInventors: Jurgen Scherkenbeck, Thomas Himmler, Klaus Stroech, Stefan Dutzmann, Gerd Hanssler, Heinz-Wilhelm Dehne
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Patent number: 5264595Abstract: Disclosed is a process for the preparation of 3,4-dichloro and 3,4-dibromo-1,2-epoxybutane by the reaction of 3,4-epoxy-1-butene with chlorine or bromine in the presence of a catalytic amount of a tertiary amine or a hydrohalide of a primary, secondary or tertiary amine. The reaction preferably is carried out by the addition of 3,4-epoxy-1-butene and chlorine or bromine to an organic, halogenation solvent containing chlorine or bromine and tertiary amine or amine hydrohalide catalyst.Type: GrantFiled: April 5, 1993Date of Patent: November 23, 1993Assignee: Eastman Kodak CompanyInventors: Stephen N. Falling, Patricia Lopez-Maldonado
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Patent number: 5216180Abstract: A herbicidal hydroxyethyl-cyclopropyl-azolyl derivative of the formula ##STR1## in which R.sup.1 represents halogen, phenyl or the grouping --Z-R.sup.3, whereinZ represents oxygen, sulphur, SO or SO.sub.2 andR.sup.3 represents alkyl, phenyl or benzyl,R.sup.2 represents alkenyl, optionally substituted furyl, optionally substituted thienyl or the radical of the formula ##STR2## wherein R.sup.4 represents difluoromethoxy, 1,1,2,2-tetrafluoroethoxy, 1,1,2-trifluoro-2-chloro-ethoxy, cyano, formyl, alkoximinoalkyl, carbalkoxy, dialkoxyalkyl, phenoxyalkyl which is optionally substituted in the phenyl moiety by halogen, or benzyloxy which is optionally substituted in the phenyl moiety by halogen andR.sup.5 represents hydrogen or halogen, orR.sup.4 and R.sup.5 are linked in the ortho-position and together represent --O--CH.sub.2 --O--, orR.sup.2 represents the radical of the formula ##STR3## in which R.sup.6 represents difluoromethoxy, 1,1,2,2-tetrafluoroethoxy or 1,1,2-trifluoro-2-chloro-ethoxy, orR.sup.Type: GrantFiled: November 1, 1991Date of Patent: June 1, 1993Assignee: Bayer AktiengesellschaftInventors: Jurgen Scherkenbeck, Monika Frie, Klaus Stroech, Thomas Himmler, Georg-W. Ludwig, Wilhelm Brandes, Stefan Dutzmann
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Patent number: 5177226Abstract: Perfluoropolyethers having fluorinated epoxy groups positioned along their perfluoropolyether chain, and free from peroxidic oxygen, are obtained by means of a low-temperature oxidation process, in the liquid phase, with molecular oxygen and in the presence of U.V. light, of a mixture of a perfluorinated monoolefin and a perfluorinated coniugated diene, and of the subsequent photochemical decomposition of the peroxy groups contained in the photoxidation product, carried out by treating the peroxy-groups-containing product with U.V. light at a temperature comprised within the range of from 0.degree. C. to 160.degree. C. Derivatives of said epoxy containing perfluoropolyethers in which the epoxy groups have been turned into functional groups.Type: GrantFiled: June 7, 1991Date of Patent: January 5, 1993Assignee: Ausimont S.p.A.Inventors: Giuseppe Marchionni, Ugo De Patto, Ezio Strepparola, Gian T. Viola
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Patent number: 5103028Abstract: Disclosed is a process for the preparation of 3,4-dichloro- and 3,4-dibromo-1,2-epoxybutane by the reaction of 3,4-epoxy-1-butane with chlorine or bromine in the presence of a quaternary ammonium or phosphonium halide compound. The reaction preferably is carried out by the addition of 3,4-epoxy-1-butane and chlorine or bromine to an organic, halogenation solvent containing chlorine or bromine and the quaternary compound.Type: GrantFiled: September 9, 1991Date of Patent: April 7, 1992Assignee: Eastman Kodak CompanyInventors: Stephen N. Falling, Patricia Lopez-Maldonado
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Patent number: 5097050Abstract: An oxirane of the formula ##STR1## in which Ar represents phenyl optionally substituted with from one to three halogen atoms,R represents alkyl having from 1 to 4 carbon atoms,X.sup.1 represents halogen,X.sup.2 represents hydrogen or halogen,X.sup.3 represents hydrogen or halogen,X.sup.4 represents hydrogen or halogen andn represents 0 to 1,useful as intermediates for the synthesis of fungicidal hydroxyalkinyl-azoles.Type: GrantFiled: February 14, 1991Date of Patent: March 17, 1992Assignee: Bayer AktiengesellschaftInventors: Reinhard Lantzcsh, Ernst Kysela, Karl H. Buchel, Stefan Dutzmann, Wilheim Brandes, Gerd Hanssler
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Patent number: 5089640Abstract: Plant growth-regulating and fungicidal compounds of the formula ##STR1## in which Ar represents optionally substituted aryl or optionally substituted heteroaryl,R.sup.1 represents hydrogen, alkyl, alkenyl, alkinyl, trialkylsilyl, optionally substituted phenylalkyl or an acyl radical,R.sup.2 represents halogen, cyano, thiocyano, alkylcarbonyloxy, alkylcarbonylthio or the groupings --X--R.sup.3 and --NR.sup.4 R.sup.5,R.sup.3 represents alkyl, cycloalkyl, alkenyl, alkinyl, hydroxyalkyl, alkylthioalkyl, carboxyalkyl, alkoxycarbonylalkyl, optionally substituted aryl, optionally substituted aralkyl or the radical of the formula ##STR2## R.sup.4 and R.sup.3 independently of one another represent hydrogen or alkyl, orR.sup.4 and R.sup.5, together with the nitrogen atom to which they are bonded, represent an optionally substituted cycloaliphatic ring which can contain further heteroatoms,X represents oxygen, sulphur, an SO group or an SO.sub.2 group, orR.sup.Type: GrantFiled: September 28, 1988Date of Patent: February 18, 1992Assignee: Bayer AktiengesellschaftInventors: Klaus Bockmann, Erik Regel, Karl H. Buchel, Klaus Lurssen, Jorg Konze, Wilhelm Brandes