The Compound Consists Of The Ring Sulfur, Carbon, And Hydrogen Patents (Class 549/83)
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Patent number: 11656503Abstract: The sealing material composition of the present disclosure includes a lactone-based compound having at least two functional groups A represented by the Chemical Formula (1) and a curing agent that is thermally reactive with the lactone-based compound and contains a compound having at least two of one or more kinds of functional groups B selected from the group consisting of a mercaptan group, a hydroxyl group, and a secondary amine group where, a is an integer of 0 or 1, and * is an atomic bond.Type: GrantFiled: July 6, 2018Date of Patent: May 23, 2023Assignee: SHARP KABUSHIKI KAISHAInventor: Masanobu Mizusaki
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Patent number: 8956803Abstract: The present invention provides a sulfonium salt used in a resist composition that can give a pattern having a high resolution, especially an excellent rectangularity of a pattern form and a small roughness, while not readily generating a defect, in the photolithography using a high energy beam as a light source; a resist composition that contains the sulfonium salt; and a patterning process using this resist composition, wherein the sulfonium salt is shown by the following general formula (1a), wherein each of R and R0 independently represents a hydrogen atom, or a linear, branched, or cyclic monovalent hydrocarbon group having 1 to 30 carbon atoms which may be optionally substituted by a heteroatom or interposed by a heteroatom.Type: GrantFiled: December 6, 2013Date of Patent: February 17, 2015Assignee: Shin-Etsu Chemical Co., Ltd.Inventors: Masaki Ohashi, Tomohiro Kobayashi, Akihiro Seki, Masayoshi Sagehashi, Masahiro Fukushima
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Publication number: 20140012018Abstract: The present invention aims to provide, with combination of a sulfolane compound and an organic alkanolamine compound, a sulfolane composition which is not likely to cause odor, can suppress pyrolysis of the sulfolane compound with a reduced amount of additives, and can reduce generation of sulfur dioxide. The present invention relates to a sulfolane composition containing a sulfolane compound represented by formula (1) and an organic alkanolamine compound, wherein R1 to R6 each independently represent a hydrogen atom or a C1-6 alkyl group.Type: ApplicationFiled: December 27, 2011Publication date: January 9, 2014Applicant: SUMITOMO SEIKA CHEMICALS CO., LTD.Inventors: Masayoshi Miyada, Katsumi Takano, Hisaaki Kanda
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Patent number: 8563779Abstract: A description is given of (4-trifluoromethyl-3-thiobenzoyl)cyclohexanediones of the formula (I) and of their use as herbicides. In this formula (I), X, R1, R2, R3, and R4 are radicals such as hydrogen and organic radicals such as alkyl. A and Z are oxygen or alkylene.Type: GrantFiled: July 19, 2011Date of Patent: October 22, 2013Assignee: Bayer CropScience AGInventors: Hartmut Ahrens, Andreas Van Almsick, Elmar Gatzweiler, Dieter Feucht, Isolde Haeuser-Hahn, Stefan Lehr, Christopher Hugh Rosinger
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Patent number: 8524763Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases, disorders or conditions that would benefit from inhibition of SOC channel activity.Type: GrantFiled: September 22, 2009Date of Patent: September 3, 2013Assignee: Calcimedica, Inc.Inventor: Jeffrey P. Whitten
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Patent number: 8513439Abstract: The invention provides a pharmaceutical composition of duloxetine or its pharmaceutically equivalent derivatives like salts, isomers, complexes, polymorphs, hydrates or esters thereof and at least one buffering agent. The duloxetine or its pharmaceutically equivalent derivative is present from about 2 mg to approximately 200 mg; and the buffering agent is present in an amount of approximately 0.1 mEq to approximately 2.5 mEq per mg of duloxetine. Also provided is a method for treating of major depressive disorder and or diabetic peripheral neuropathic pain comprising administering to a mammal in need of such treatment a therapeutically effective amount of a composition.Type: GrantFiled: January 10, 2012Date of Patent: August 20, 2013Assignee: Wockhardt LimitedInventor: Ramesh Sesha
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Patent number: 8455667Abstract: The invention provides for the first time an oral liquid composition of duloxetine or its pharmaceutically equivalent derivatives like salts, isomers, complexes, polymorphs, hydrates or esters thereof. The duloxetine or its pharmaceutically equivalent derivative is present from about 2 mg to approximately 200 mg; and a buffering agent was used to stabilize the acid sensitive duloxetine. The composition has duloxetine from about 0.1 mEq to about 2.5 mEq per mg of duloxetine. The invention further discloses an oral liquid composition of duloxetine or its pharmaceutically equivalent derivative wherein the degradation product 1-Naphthol is less than 0.01%. Also provided is a method for treating of major depressive disorder and or diabetic peripheral neuropathic pain comprising administering to a mammal in need of such treatment a therapeutically effective amount of a composition.Type: GrantFiled: April 10, 2012Date of Patent: June 4, 2013Assignee: Wockhardt LimitedInventor: Ramesh Sesha
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Publication number: 20130065937Abstract: A compound represented by the general formula (C): (wherein R101 represents a substituted or unsubstituted aromatic heterocyclic group, R102, R103, R104 and R105 may be the same or different, and each represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a haloalkyl group having 1 to 3 carbon atoms, and R106 represents a hydrogen atom, or a saturated or unsaturated hydrocarbon group which is a straight or branched chain having 1 to 12 carbon atoms, but excluded is the case where R101 is a 3-furyl group, R102, R103, R104 and R105 are all methyl groups, and R106 is a methyl group, a 4-methyl-3-pentenyl group or a 4,8-dimethyl-3,7-nonadienyl group); or a pharmaceutically acceptable salt thereof has selective inhibitory activity on hypoxic cell growth in a broad range of the concentration and therefore is useful as an active ingredient of a medicament for cancer prevention or treatment.Type: ApplicationFiled: May 6, 2011Publication date: March 14, 2013Applicant: Osaka UniversityInventors: Motomasa Kobayashi, Naoyuki Kotoku, Masayoshi Arai, Takashi Kawachi
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Patent number: 8236845Abstract: The present invention relates to heterocyclyl-substituted-tetrahydro-naphthalen-amine compounds of general formula (I) and compositions thereof, methods for their preparation, and the use of said compounds for the treatment or prophylaxis of various disorders of humans or animals.Type: GrantFiled: March 28, 2008Date of Patent: August 7, 2012Assignee: Laboratorios del Dr. Esteve, S.A.Inventors: Monica Garcia-Lopez, Antonio Torrens-Jover, Helmut H. Buschmann
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Patent number: 8153824Abstract: The invention provides for the first time an oral liquid composition of duloxetine or its pharmaceutically equivalent derivatives like salts, isomers, complexes, polymorphs, hydrates or esters thereof. The duloxetine or its pharmaceutically equivalent derivative is present from about 2 mg to approximately 200 mg; and a buffering agent was used to stabilize the acid sensitive duloxetine. The composition has duloxetine from about 0.1 meq to about 2.5 mEq per mg of duloxetine. The invention further discloses an oral liquid composition of duloxetine or its pharmaceutically equivalent derivative wherein the degradation product 1-Naphthol is less than 0.01%. Also provided is a method for treating of major depressive disorder and or diabetic peripheral neuropathic pain comprising administering to a mammal in need of such treatment a therapeutically effective amount of a composition.Type: GrantFiled: June 22, 2005Date of Patent: April 10, 2012Assignee: The Wockhardt CompanyInventor: Ramesh Sesha
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Patent number: 8093408Abstract: The invention provides a pharmaceutical composition of duloxetine or its pharmaceutically equivalent derivatives like salts, isomers, complexes, polymorphs, hydrates or esters thereof and at least one buffering agent. The duloxetine or its pharmaceutically equivalent derivative is present from about 2 mg to approximately 200 mg; and the buffering agent is present in an amount of approximately 0.1 mEq to approximately 2.5 mEq per mg of duloxetine. Also provided is a method for treating of major depressive disorder and or diabetic peripheral neuropathic pain comprising administering to a mammal in need of such treatment a therapeutically effective amount of a composition.Type: GrantFiled: June 21, 2005Date of Patent: January 10, 2012Assignee: The Company WockhardtInventor: Ramesh Sesha
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Patent number: 8067418Abstract: There is provided compounds of formula I, wherein the dotted line, X1, X2, X3, A, Y1, Y2, Y3, Y4, Z1, Z2, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful as selective agonists of the AT2 receptor, and thus, in particular, in the treatment of inter alia gastrointestinal conditions, such as dyspepsia, IBS and MOF, and cardiovascular disorders.Type: GrantFiled: April 12, 2006Date of Patent: November 29, 2011Assignee: Vicore Pharma ABInventors: Mathias Alterman, Anders Hallberg, Xiongyu Wu
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Patent number: 8058457Abstract: A star-shaped oligothiophene-arylene derivative in which an oligothiophene having p-type semiconductor characteristics is bonded to an arylene having n-type semiconductor characteristics positioned in the central moiety of the molecule and forms a star shape with the arylene, thereby simultaneously exhibiting both p-type and n-type semiconductor characteristics. Further, an organic thin film transistor using the oligothiophene-arylene derivative. The star-shaped oligothiophene-arylene derivative can be spin-coated at room temperature, leading to the fabrication of organic thin film transistors simultaneously satisfying the requirements of high charge carrier mobility and low off-state leakage current.Type: GrantFiled: February 17, 2010Date of Patent: November 15, 2011Assignee: Samsung Electronics Co., Ltd.Inventors: Kook Min Han, Eun Jeong Jeong, Chang Ju Kim, Eun Kyung Lee
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Publication number: 20110102970Abstract: The present invention relates to a monomer having the general formula (I) in which R1 and R2 stand, independently of one another, for hydrogen, for an optionally substituted C1-C20-alkyl group or C1-C20-oxyalkyl group, optionally interrupted by 1 to 5 oxygen atoms and/or sulfur atoms, or jointly for an optionally substituted C1-C20-dioxyalkylene group or C6-C20-dioxyarylene group, wherein the monomer has a colour in a range of a Hazen colour number determined according to test method described herein of at least 20, to a Gardner colour number determined according to test method described herein of not more than 5. The present invention also relates to a method for the manufacture of a capacitor, a capacitor obtained by this method and to the use of a monomer.Type: ApplicationFiled: September 30, 2010Publication date: May 5, 2011Applicant: H.C. Starck Clevios GmbHInventors: Udo Merker, Klaus Wussow, Knud Reuter, Andreas Elschner
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Publication number: 20100267857Abstract: Provided are a salt compound, cationic polymerization initiator and cationically polymerizable composition, which have a superior acid-generating capacity and high sensitivity, and are free from coloration. The salt compound is represented by the following general Formula (1): (wherein, R01 to R05 each independently represents a group selected from a hydrogen atom, a fluorine atom and —YR group, one of the R01 to R05 being a —YR group and at least two of the R01 to R05 being fluorine atoms; Y represents an oxygen atom or a sulfur atom; R represents a C1-C4 alkyl group; Ctp+ represents a p-valent cation, the p being 1 or 2; and n represents a coefficient required for maintaining electrical neutrality).Type: ApplicationFiled: October 28, 2008Publication date: October 21, 2010Applicant: ADEKA CORPORATIONInventors: Kentaro Kimura, Shohei Fujita, Tomoya Tamachi
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Publication number: 20100217015Abstract: A process is described for the preparation of substituted heteroaromatics of the general formula (I) where X is oxygen, sulphur or NR5 where R5 is hydrogen, C1-C20-alkyl or C5-C6-aryl and R4 is C1-C20-alkyl, C5-C6-aryl or heteroaryl, R1, R2, R3 is hydrogen, halogen, C1-C20-alkyl, C5-C6-aryl or heteroaryl, by reaction A) of a halogenated heteroaromatic of the general formula (II) where X has the meaning given for formula (I) and R6 is bromine, iodine or chlorine and R1, R2 and R3 have the meaning given for formula (I), with a Grignard reagent of the general formula (III) R4MgHal??(III) where R4 has the meaning given for formula (I) and Hal is bromine, iodine or chlorine or B) reaction of the halogenated heteroaromatics of the formula (II) with magnesium firstly to give a Grignard compound of the general formula (IIIa) where Hal is bromine, iodine or chlorine and X and R1, R2 and R3 have the meaning given for formula (I), and further reaction with a halogenated compound of theType: ApplicationFiled: May 27, 2008Publication date: August 26, 2010Applicant: SALTIGO GMBHInventors: Antje Hieronymi, Lars Rodefeld
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Patent number: 7767626Abstract: 3-Arylphenyl sulfide derivatives represented by general formula (I): (wherein R is a C2-C6 alkyl group, a C2-C6 alkenyl group, a C2-C6 alkynyl group or the like, B0 to B2 and B3 are hydrogen atoms, halogen atoms, cyano groups, C1-C4 haloalkyl groups or the like, n is 0, 1 or 2, and Ar is a phenyl ring, a pyridine ring, a thiophene ring, a pyrazole ring or the like), and insecticides and miticides containing the 3-arylphenyl sulfide derivatives as an active ingredient.Type: GrantFiled: November 12, 2008Date of Patent: August 3, 2010Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.Inventors: Keiji Toriyabe, Nobuo Takefuji, Minoru Itou, Tetsuya Hirade, Kiyotoshi Nishiyama, Mitsuharu Asahida, Yasunobu Maeda, Nobuhide Wada, Toyokazu Fujisawa, Hiroyuki Yano, Masaaki Komatsu, Osamu Tada
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Patent number: 7692029Abstract: A star-shaped oligothiophene-arylene derivative in which an oligothiophene having p-type semiconductor characteristics is bonded to an arylene having n-type semiconductor characteristics positioned in the central moiety of the molecule and forms a star shape with the arylene, thereby simultaneously exhibiting both p-type and n-type semiconductor characteristics. Further, an organic thin film transistor using the oligothiophene-arylene derivative. The star-shaped oligothiophene-arylene derivative can be spin-coated at room temperature, leading to the fabrication of organic thin film transistors simultaneously satisfying the requirements of high charge carrier mobility and low off-state leakage current.Type: GrantFiled: April 28, 2005Date of Patent: April 6, 2010Assignee: Samsung Electronics Co., Ltd.Inventors: Kook Min Han, Eun Jeong Jeong, Chang Ju Kim, Eun Kyung Lee
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Patent number: 7628938Abstract: The present invention provides a photochromic compound that is colored when irradiated with visible light and quickly faded when set in a dark place. The photochromic compound according to the present invention is expressed by the following general formula (I): where each of A1, A2 and A3 is a five-member rings forming a 6?-electron system, the three rings being identical, partially identical or totally different from each other, and each ring may have a substituent; B1 and B2 are functional groups, each having an atomic number of five or larger, including a ring compound, and bonded to the 2-carbon of each of A2 and A3, respectively; and R1, R2 and R3 are substituents identical to or different from each other. This compound is highly colorable and durable even when it is dispersed into plastic macromolecular materials. Therefore, it is suitable as a dye material for sunglasses or similar products.Type: GrantFiled: March 21, 2007Date of Patent: December 8, 2009Assignee: National University Corporation Nara Institute of Science and TechnologyInventors: Tsuyoshi Kawai, Takuya Nakajima, Shigekazu Kawai
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Patent number: 7528261Abstract: A small molecule compound including at least one type of an optionally substituted indolocarbazole moiety and at least one divalent linkage.Type: GrantFiled: December 17, 2007Date of Patent: May 5, 2009Assignee: Xerox CorporationInventors: Yuning Li, Beng S Ong, Yiliang Wu, Ping Liu
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Patent number: 7521170Abstract: The present application relates to a compound of formula A-X—B, where (i)A-X—B form an ionic compound Ai Xi Bi where Ai and Bi are each individually an organic onium cation; and Xi is anion of the formula Q-R500—SO3? or (ii)A-X—B form a non-ionic compound Ac-Xc-Bc, where Ai, Bi, Q, R500, Ac, Bc, and Xc are defined herein. The compounds are useful as photoactive materials.Type: GrantFiled: February 16, 2006Date of Patent: April 21, 2009Assignee: AZ Electronic Materials USA Corp.Inventors: M. Dalil Rahman, Francis M. Houlihan, Munirathna Padmanaban, SangHo Lee, Ralph R. Dammel, David Rentkiewicz, Clement Anyadiegwu
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Publication number: 20090020732Abstract: Provided is method of selectively separating carbon nanotubes into metallic carbon nanotubes and semiconducting carbon nanotubes, the method including: preparing a mixture including a dispersant, carbon nanotubes, and a solvent; dispersing the carbon nanotubes in the mixture; and separating the semiconducting carbon nanotubes from the mixture in which the carbon nanotubes are dispersed, wherein the dispersant is an oligomer including about 2 to about 24 repeat units, each including a head moiety and a tail moiety, wherein the head moiety comprises 1 to about 5 aromatic hetero rings, and the tail moiety comprises a hydrocarbon chain or chains connected to the head moiety.Type: ApplicationFiled: May 19, 2008Publication date: January 22, 2009Applicant: SAMSUNG ELECTRONICS CO., LTD.Inventors: Hyeon-Jin SHIN, Jae-young CHOI, Seong-jae CHOI, Seon-mi YOON
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Patent number: 7411093Abstract: The present invention relates to compounds of formula (I) wherein R1 is as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP-IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.Type: GrantFiled: December 13, 2005Date of Patent: August 12, 2008Assignee: Hoffman-La Roche Inc.Inventors: Markus Boehringer, Daniel Hunziker, Bernd Kuhn, Bernd Michael Loeffler, Hans Peter Marty, Patrizio Mattei, Robert Narquizian
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Patent number: 7408188Abstract: An organic semiconductor material characterized by having a structure represented by chemical formula 1, the planarity of a main chain A1-X-A2 being disintegrated by steric hindrance between B1 and X and steric hindrance between B2 and X, the organic semiconductor material having a number average molecular weight of about 2,000 to about 200,000: wherein A1, A2, B1, B2 and X each have a skeleton structure comprising L 6 ? electron rings, M 8 ? electron rings, N 10 ? electron rings, O 12 ? electron rings, P 14 ? electron rings, Q 16 ? electron rings, R 18 ? electron rings, S 20 ? electron rings, T 22 ? electron rings, U 24 ? electron rings, and V 26 ? electron rings, wherein L, M, N, O, P, Q, R, S, T, U, and V are each an integer of 0 (zero) to 6 and L+M+N+O+P+Q+R+S+T+U+V=1 to 6; and B1 and B2 have an alkyl group.Type: GrantFiled: June 7, 2006Date of Patent: August 5, 2008Assignee: Dai Nippon Printing Co., Ltd.Inventors: Shigeru Sugawara, Hiroki Maeda, Ken Tomino, Masanao Matsuoka
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Patent number: 7390613Abstract: The present application relates to a compound of formula Ai Xi Bi where Ai and Bi are each individually an organic onium cation; and Xi is anion of the formula ?O3S—CF2CF2OCF2CF2—SO3?. The compounds are useful as photoactive materials.Type: GrantFiled: December 4, 2006Date of Patent: June 24, 2008Assignee: AZ Electronic Materials USA Corp.Inventors: M. Dalil Rahman, David L. Rentkiewicz
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Patent number: 7342042Abstract: Improved cyclamenaldehyde derivatives, and fragrances and flavorings including the derivatives, are disclosed. In particular, the derivatives maintain the fragrance characteristics of cyclamenaldehyde, while enhancing the odorant intensity. In addition, when present in a fragrance they heighten the effect of the remainder of the formulation. Further, they heighten the perceived intensity of other olfactory stimuli, e.g. food and ambient smells. Also disclosed are methods of making the derivatives, and articles of manufacture including the derivatives. The derivatives are prepared by replacing the phenyl moiety in cyclamenaldehyde with a thiophene moiety, which can be unsubstituted, or substituted with one or two lower alkyl, preferably isopropyl groups. The aldehyde group in cyclamenaldehyde can also be replaced with an acetal, methyl ether, nitrile or ester functionality.Type: GrantFiled: June 16, 2004Date of Patent: March 11, 2008Assignee: Flexitral, Inc.Inventor: Luca Turin
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Patent number: 7332513Abstract: Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.Type: GrantFiled: November 4, 2005Date of Patent: February 19, 2008Assignee: Renopharm Ltd.Inventors: Peter Assaf, Elham Gazaleen-Mariee, Michael Naveh
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Publication number: 20080006797Abstract: The present invention provides a photochromic compound that is colored when irradiated with visible light and quickly faded when set in a dark place. The photochromic compound according to the present invention is expressed by the following general formula (I): where each of A1, A2 and A3 is a five-member rings forming a 6?-electron system, the three rings being identical, partially identical or totally different from each other, and each ring may have a substituent; B1 and B2 are functional groups, each having an atomic number of five or larger, including a ring compound, and bonded to the 2-carbon of each of A2 and A3, respectively; and R1, R2 and R3 are substituents identical to or different from each other. This compound is highly colorable and durable even when it is dispersed into plastic macromolecular materials. Therefore, it is suitable as a dye material for sunglasses or similar products.Type: ApplicationFiled: March 21, 2007Publication date: January 10, 2008Applicant: NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Tsuyoshi Kawai, Takuya Nakajima, Shigekazu Kawai
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Patent number: 7294639Abstract: Novel pharmaceutical/cosmetic compositions contain at least one biaromatic ligand activator of a PPAR? receptor, such biaromatic ligand having the structural formula (I): and are well suited, inter alia, for regulating and/or restoring skin lipid metabolism, for treating a wide variety of dermatological afflictions, and for preventing and/or treating the signs of aging and/or dry skin.Type: GrantFiled: August 18, 2006Date of Patent: November 13, 2007Assignee: Galderma Research & DevelopmentInventors: Jean-Michel Bernardon, Laurence Clary, Eric Terranova
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Patent number: 7273856Abstract: Described herein are compounds of formula (I) useful as antagonists of tachykinins in general, and in particular of neurokinin A; and the pharmaceutical formulations comprising the compounds of formula (I)Type: GrantFiled: October 28, 2002Date of Patent: September 25, 2007Assignee: Menarini Ricerche S.P.A.Inventors: Alessandro Sisto, Valerio Caciagli, Maria Altamura, Alessandro Giolitti, Valentina Fedi, Antonio Guidi, Danilo Giannotti, Nicholas Harmat, Rossano Nannicini, Franco Pasqui, Carlo Alberto Maggi
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Patent number: 7247736Abstract: The present invention provides a compound capable of binding to the ubiquinone binding site of DHODH which contains a non-aromatic ring system as a core structure, a group capable of interacting with structural elements of subsite 2 or 3 of the ubiquinone binding site of DHODH and a group capable of interacting hydrophobically with structural elements of subsite 1 of the ubiquinone binding site of DHODH. Furthermore, the present invention provides a compound capable of binding to the ubiquinone binding site of DHODH which contains an aromatic ring system as a core structure, a group capable of interacting with residues His 56 and/or Tyr 356 of subsite 3 of the ubiquinone binding site of DHODH and a group capable of interacting hydrophobically with structural elements of subsite 1 of the ubiquinone binding site of DHODH.Type: GrantFiled: November 10, 2004Date of Patent: July 24, 2007Assignee: 4SC AGInventors: Johann Leban, Bernd Kramer, Roland Baumgartner, Katharina Aulinger-Fuchs, Stefan Tasler
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Patent number: 7247735Abstract: In the case of the materials according to the invention, the charge carrier mobility in the correspondingly prepared films is achieved if the molecules are composed in such a way that side chains—consisting of conjugated aromatic or heteroaromatic systems—are attached in direct conjugation to a central aromatic or heteroaromatic ring so that the total molecule acquires an octupolar structure. This octupolar structure permits an effective ?-? interaction of the molecules with one another in a manner such that stacking of a plurality of molecules along an imaginary axis (central ring) can take place and various stacks from among these stacks can interact with one another by intermeshing of the side chains. The electronic properties of the materials are determined both by the arrangement of the molecules in a layer and by the molecular design.Type: GrantFiled: January 24, 2005Date of Patent: July 24, 2007Assignee: Infineon Technologies AGInventors: Marcus Halik, Hagen Klauk, Guenter Schmid
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Patent number: 7227040Abstract: A branched composition can be formed by reacting a reagent containing a saturated hydrocarbon moiety in the presence of (a) a catalyst capable of activating a carbon-hydrogen bond therein and (b) a branching reagent having a moiety that binds to the carbon atom in the carbon-hydrogen bond upon extraction of the hydrogen atom from that carbon-hydrogen bond. Suitable catalysts are those that comprise a transition metal cation possessing multiple oxidation states that is embedded in an anion that is a transition metal oxide possessing a higher oxidation state for the metal therein than the metal in the cation.Type: GrantFiled: June 7, 2004Date of Patent: June 5, 2007Assignee: Akzo Nobel N.V.Inventors: Zongchao Zhang, Xiaolei Sun
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Patent number: 7217295Abstract: The invention relates to the use of a composition comprising at least one conductive polymer in a cosmetically acceptable medium, said polymer being in soluble form in said medium, as, or for the manufacture of, cosmetic products for giving a visual effect to human keratin fibers and more particularly the hair, and also, when said conductive polymer absorbs in the visible region, as, or for the manufacture of, cosmetic products intended to color said fibers. The invention also relates to the corresponding treatment process.Type: GrantFiled: January 31, 2003Date of Patent: May 15, 2007Assignee: L'Oreal S.A.Inventors: Henri Samain, Grégory Plos, Nathalie Mougin
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Patent number: 7205414Abstract: A method for the formation of 3-alkylthiophenes or 3-arylthiophenes from 3-halothiophenes. More particularly, improvements on the Kumada coupling reaction for the production of 3-alkylthiophenes or 3-arylthiophenes by reacting a 3-halothiophene with an alkylmagnesiumhalide or arylmagnesiumhalide Grignard reagent in the presence of a catalyst and a 2-methyl tetrahydrofuran solvent. The 2-methyl tetrahydrofuran solvent allows for higher concentrations of the Grignard reagent with minimal or no dithienyl side product generation, achieving higher product yields and at a lower cost than other known methods.Type: GrantFiled: January 12, 2005Date of Patent: April 17, 2007Assignee: Honeywell International Inc.Inventors: Christian Werner, Frauke Platz, Andreas Kanschik-Conradsen
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Patent number: 7202368Abstract: A process for preparing an optionally substituted 4-benzimidazol-2-ylmethylamino)benzamidine, the process comprising: (a) condensing an optionally suitably substituted diaminobenzene with 2-[4-(1,2,4-oxadiazol-5-on-3-yl)phenylamino]acetic acid; (b) hydrogenating the product obtained from step (a); and (c) optionally carboxylating the amidino group of the product obtained from step (b).Type: GrantFiled: June 9, 2005Date of Patent: April 10, 2007Assignee: Boehringer Ingelheim International GmbHInventors: Georg Zerban, Arndt Hausherr, Kerstin Schlarb, Heinz-Peter Schmitt, Bjoern Weyell, Gunter Koch, Rainer Hamm
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Patent number: 7192978Abstract: New pyrrolidinium derivatives having the chemical structure of general formula (I) are disclosed; as well as processes for their preparation, pharmaceutical compositions comprising them and their use in therapy as antagonists of M3 muscarinic receptors.Type: GrantFiled: April 11, 2003Date of Patent: March 20, 2007Assignee: Almirall Prodesfarma AGInventors: Maria Prat Quinones, Maria Dolors Fernandez Forner
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Patent number: 7122564Abstract: Novel pharmaceutical/cosmetic compositions contain at least one biaromatic ligand activator of a PPAR? receptor, such biaromatic ligand having the structural formula (I): and are well suited, inter alia, for regulating and/or restoring skin lipid metabolism, for treating a wide variety of dermatological afflictions, and for preventing and/or treating the signs of aging and/or dry skin.Type: GrantFiled: January 26, 2005Date of Patent: October 17, 2006Assignee: Galderma Research & DevelopmentInventors: Jean-Michel Bernardon, Laurence Clary, Eric Terranova
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Patent number: 7109354Abstract: Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R1, R2, R3, R4 and R7 are defined in the specification, Z is SO or SO2, and Ar is an aromatic or heteroaromatic group as defined herein.Type: GrantFiled: May 28, 2003Date of Patent: September 19, 2006Assignee: 3-Dimensional Pharmaceuticals, Inc.Inventors: Nalin Subasinghe, Ehab Khalil, Kristi Leonard, Farah Ali, Heather Rae Hufnagel, Jeremy M. Travins, Shelley K. Ballentine, Kenneth T. Wilson, Maxwell D. Cummings, Wenxi Pan, Joan Gushue, Sanath Meegalla, Mark Wall, Jinsheng Chen, M. Jonathan Rudolph, Hui Huang
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Patent number: 6992101Abstract: The present invention provides compounds of formula (I) the prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein R?, R?, R??, and Z are as defined herein; pharmaceutical compositions thereof; and uses thereof in treating diabetes, insulin resistance, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, cataracts, hyperglycemia, hypercholesterolemia, hypertension, hyperinsulinemia, hyperlipidemia, atherosclerosis, and tissue ischemia.Type: GrantFiled: November 6, 2003Date of Patent: January 31, 2006Assignee: Pfizer, Inc.Inventors: Donald L. Bussolotti, Ronald B. Gammill, Jana Polivkova
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Patent number: 6916938Abstract: There is provided a method for preparing a sulfone or sulfoxide compound, characterized in that a sulfide compound is allowed to react with hydrogen peroxide in the presence of a metal oxide catalyst formed by the reaction of hydrogen peroxide with at least one metal or metal compound selected from tungsten metal; molybdenum metal; a tungsten compound comprising tungsten and a Group IIIb, IVb, Vb, or VIb element exclusive of oxygen; and a molybdenum compound comprising molybdenum and a Group IIIb, IVb, Vb, or VIb element exclusive of oxygen.Type: GrantFiled: January 23, 2003Date of Patent: July 12, 2005Assignee: Sumitomo Chemical Company, LimitedInventors: Jun Oguma, Koji Hagiya, Takashi Miyawaki
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Patent number: 6913710Abstract: The invention relates to new reactive mesogenic benzodithiophene derivatives, their use as semiconductors or charge transport materials, in optical, electro-optical or electronic devices like for example liquid crystal displays, optical films, organic field effect transistors (FET or OFET) for thin film transistor liquid crystal displays and integrated circuit devices such as RFID tags, electroluminescent devices in flat panel displays, and in photovoltaic and sensor devices, and to a field effect transistor, light emitting device or ID tag comprising the reactive mesogenic benzodithiophenes.Type: GrantFiled: April 24, 2003Date of Patent: July 5, 2005Assignee: Merck Patent GmbHInventors: Louise Farrand, Martin Heeney, Steven Tierney, Mark Giles, Marcus Thompson, Maxim Shkunov, David Sparrowe, Iain McCulloch
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Patent number: 6878801Abstract: Novel polythiophenes which exhibit strong main chain absorption in the ultraviolet to visible region, show optical activity depending on the polymeric chain alone, and comprise as repeating units thiophene rings containing chiral substituent groups, and are represented by the following general formula: (wherein R1 and R2 are the same or different, each representing a hydrogen atom or an organic group, of which at least one is an enantiopure alkyl group with a branch structure at the ?-position, and n represents the number of repeating units selected from 10 to 100,000).Type: GrantFiled: January 8, 2003Date of Patent: April 12, 2005Assignees: Japan Science and Technology, Nippon Telegraph and Telephone CorporationInventors: Michiya Fujiki, Hiroshi Nakashima, Julian R. Koe, Masao Morita, Hiromi Tamoto
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Patent number: 6858602Abstract: Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis, are disclosed.Type: GrantFiled: October 14, 2003Date of Patent: February 22, 2005Assignee: Wellstat Therapeutics CorporationInventors: Shalini Sharma, Reid W. von Borstel
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Patent number: 6809090Abstract: N-(imino)amines and their preparation and their use as NO synthase inhibitors and selective or non-selective traps for a reactive oxygen species.Type: GrantFiled: July 1, 2003Date of Patent: October 26, 2004Inventors: Dennis Bigg, Pierre-Etienne Chabrier de Lassauniere, Serge Auvin, Jeremiah Harnett, Gérard Ulibarri
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Patent number: 6656939Abstract: This invention describes novel pyrazole compounds of formula III: wherein Z1, Z2, and Z3 are as described in the specification; Q is —S—, —O—, —N(R4)—, or —CH(R6)—; R1 is T-Ring D, wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; and R2 and R2′ are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of Aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.Type: GrantFiled: December 20, 2001Date of Patent: December 2, 2003Assignee: Vertex Pharmaceuticals IncorporatedInventors: David Bebbington, Jean-Damien Charrier
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Patent number: 6639083Abstract: The invention relates to a process for preparing 2-thienyl-2-ethanol, in which: a) thiophene is metallated using an alkali metal, in the presence of an electron transfer agent, b) the compound obtained is treated with ethylene oxide, c) the thienyl derivative thus formed is hydrolyzed, to give the desired compound. 2-Thienyl-2-ethanol is a synthetic intermediate.Type: GrantFiled: April 19, 2002Date of Patent: October 28, 2003Assignee: Sanofi-SynthelaboInventors: Michel Biard, André Bousquet
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Patent number: 6479514Abstract: Compounds of formula (I) in which the substituents and symbols have the meanings indicated in the description, are suitable for the control of Helicobacter bacteria.Type: GrantFiled: November 17, 2000Date of Patent: November 12, 2002Assignee: Altana Pharma AGInventors: Peter Zimmerman, Gerhard Grundler
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Patent number: 6426354Abstract: Novel thiol derivatives of formula I or of the formula Ia wherein the variables have the meanings as defined hereinbefore.Type: GrantFiled: October 16, 2000Date of Patent: July 30, 2002Assignee: Novartis AGInventors: Cynthia Anne Fink, Fariborz Firooznia
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Patent number: 6392047Abstract: Biaryls, e,g,. biphenyls, phenylpyridines, phenylfurans, phenylpyrroles, phenylthiophenes, bipyridines, pyridylfurans or pyridylpyrroles are prepared in high yields by coupling aromatics with an aromatic boric acid or boric ester in the presence of a palladaphosphacyclobutane catalyst.Type: GrantFiled: July 13, 2000Date of Patent: May 21, 2002Assignee: Clariant GmbHInventors: Holger Geissler, Steffen Haber, Andreas Meudt, Frank Vollmueller, Stefan Scherer