Acyclic Carbon Bonded Directly To Three Benzene Rings Or To Two Benzene Rings And A Cyclohexadienyl Ring, Which Acyclic Carbon May Not Be Bonded To A Fourth Carbon (e.g., Triphenylmethane Dyestuffs, Etc.) Patents (Class 552/101)
  • Patent number: 9150597
    Abstract: Provided herein is a compound of Formula 1: or an isomer thereof, or a salt of the compound or of an isomer thereof, wherein R1 and R2 are each independently selected from the group consisting of hydrogen, halogen, alkyl, haloalkyl, alkoxy, haloalkoxy, dialkylamino, halodialkylamino, hydroxyalkyl, and cyano, and R is selected from the group consisting of alkyl, haloalkyl, cyanoalkyl, alkoxy, dialkylamino, and cyano.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: October 6, 2015
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Daniel J. Mindiola, Ba L. Tran
  • Patent number: 8911647
    Abstract: Disclosed is a photosensitive resin composition for a color filter including (A) a dye-polymer composite wherein the dye includes a repeating unit derived from a compound represented by the following Chemical Formula 1, wherein in Chemical Formula 1, each substituent is the same as defined in the detailed description; (B) a binder resin; (C) a photopolymerizable monomer; (D) a photopolymerization initiator; and (E) a solvent.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: December 16, 2014
    Assignee: Cheil Industries Inc.
    Inventors: Sang-Won Cho, Won-A Noh, Soo-Young Heo, Han-Chul Hwang, Gyu-Seok Han
  • Patent number: 8906271
    Abstract: Disclosed is a photosensitive resin composition for a color filter and a color filter using the same. The photosensitive resin composition for a color filter includes (A) a dye-polymer composite including a structural unit derived from the compound represented by the following Chemical Formula 1, wherein each substituent is the same as defined in the detailed description; (B) an acryl-based photopolymerizable monomer; (C) a photopolymerization initiator; and (D) a solvent.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: December 9, 2014
    Assignee: Cheil Industries Inc.
    Inventors: Yeon-Soo Lee, Seong-Ryong Nam, Taek-Jin Baek, Sang-Won Cho, Jae-Hyun Kim, Chang-Min Lee, Gyu-Seok Han
  • Patent number: 8436195
    Abstract: The use of malachite green in the form of a tetramethyldiamino-triphenyl-carbinol anhydro-oxalate [(C23H25N2)—(C2HO4)]2—C2H2O4 of the following structural formula as a drug for treating malignant neoplasms administered in a single dose of 1 to 2 g. Malachite green can be used when dissolved in an aqueous solution or in a physiological salt solution or in spirit. In different cases, the malachite green solution is perorally administered before and after a meal or is injected per rectum, or a 1% malachite green solution is intravenously introduced, or the malachite green is applied as a rectal suppository component or as a component of 1-5% ointment. The medicinal agent exhibits an extended range of therapeutic actions with respect to different oncological diseases, is freely available, not expensive, non-toxic, does not generate side effects when used in pharmaceutically acceptable doses, and makes it possible to reduce a treating time and to increase the efficiency of treatment.
    Type: Grant
    Filed: November 29, 2006
    Date of Patent: May 7, 2013
    Inventor: Mikhail Vladimirovich Kutushov
  • Patent number: 8318443
    Abstract: A reagent for use in detecting an analyte comprises a fluorescent energy donor and an energy acceptor, wherein the energy acceptor is of the general formula: and wherein the distance between the energy donor and the energy acceptor of the reagent is capable of modulation by a suitable analyte to be detected.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: November 27, 2012
    Assignee: Medtronic Minimed, Inc.
    Inventors: Jens Christian Norrild, Bo Wegge Laursen
  • Patent number: 8282862
    Abstract: A triphenylmethane-based complex dye, a photosensitive resin composition, and a color filter, the triphenylmethane-based complex dye being represented by the following Chemical Formula 1:
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: October 9, 2012
    Assignee: Cheil Industries, Inc.
    Inventors: Nam-Gwang Kim, Jianhua Li, Sina Maghsoodi, Shahrokh Motallebi, Jae-Hyun Kim, Gyu-Seok Han
  • Patent number: 7597723
    Abstract: This invention relates to unsubstituted and polymeric leuco colorants for use as consumer product additives to indicate a product function by color change, to make attractive or distinctive visual effects, or to provide latent or delayed color generation. The colorants may be present in a stable, colorless state and may be transformed to an intense colored state upon exposure to certain physical or chemical changes. Alternatively, the colorants may be transformed from one color to another color upon exposure to certain physical or chemical changes. The colored form of the unsubstituted or polymeric leuco colorant may be transient, since the colorant can revert back to its colorless form or its original color after the physical or chemical activation has been removed or changed. Polymeric leuco colorants are typically comprised of at least two components: at least one leuco chromophore component and at least one polymeric component.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: October 6, 2009
    Assignee: Milliken & Company
    Inventors: Patrick D Moore, Eduardo Torres
  • Patent number: 7097669
    Abstract: Colorant compositions are useful for a wide variety of product applications. For example, colorants are used in tinting of polymers, providing colors to aqueous solution(s), and affording color to solid or semi-solid products such as detergents. Disclosed herein are colorant compositions having a triphenylmethane (“TPM”) derived structure having improved stability to alkaline conditions. Thus, the colorant compositions resist decolorization, even at relatively high pH levels. The colorant compositions of the invention are useful as applied in polyolefins, such as polypropylene and polyethylene, as examples. These colorant compositions also may be employed in thermoplastics, such as PET, for example.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: August 29, 2006
    Assignee: Milliken & Company
    Inventors: Eric B. Stephens, Pat Moore
  • Publication number: 20040214918
    Abstract: Disclosed are colorant compounds of the formula 1
    Type: Application
    Filed: April 24, 2003
    Publication date: October 28, 2004
    Applicant: Xerox Corporation
    Inventors: Jeffery H. Banning, Donald R. Titterington, Clifford R. King
  • Publication number: 20040097725
    Abstract: The present invention relates to charge transport compositions. The invention further relates to electronic devices in which there is at least one active layer comprising such charge transport compositions.
    Type: Application
    Filed: July 2, 2003
    Publication date: May 20, 2004
    Inventors: Norman Herron, Nora Sabina Radu, Eric Maurice Smith, Ying Wang
  • Publication number: 20040054203
    Abstract: The present invention relates to a method for converting a substituted or unsubstituted solid supported trityl alcohol to a substituted or unsubstituted solid supported trityl chloride.
    Type: Application
    Filed: August 19, 2003
    Publication date: March 18, 2004
    Inventors: James Charles Bohling, William Joseph Zabrodski
  • Patent number: 6603029
    Abstract: The invention provides a partially protected trisphenol having the general formula (I) wherein R1 is an alkyl group of 1-4 carbons or an alkoxyl group of 1-4 carbons, R2 is an alkyl group of 1-6 carbons or a cycloalkyl group of 5 or 6 carbons, X1 is a hydrogen atom, an alkoxycarbonylmethyl group wherein the alkyl group has 1-4 carbons, an alkoxycarbonyl group wherein the alkyl group has 1-4 carbons or a tetrahydropyranyl group, X2 is a hydrogen atom, an alkoxycarbonylmethyl group wherein the alkyl group has 1-4 carbons, an alkoxycarbonyl group wherein the alkyl group has 1-4 carbons or a tetrahydropyranyl group, provided that when X1 is a hydrogen atom, X2 is not a hydrogen atom, and when X2 is a hydrogen atom, X1 is not a hydrogen atom; and m is an integer of 0, 1 or 2, and n is an integer of 0, 1, 2 or 3.
    Type: Grant
    Filed: December 18, 2000
    Date of Patent: August 5, 2003
    Assignee: Honshu Chemical Industry Co., Ltd.
    Inventors: Taiichi Shiomi, Sachiko Miyagi, Toru Masuda
  • Patent number: 6586256
    Abstract: Chemical sensor compositions and methods for quantifying analytes are described. The chemical sensors include analyte-binding moieties and reporter moieties covalently attached to a framework including two trityl groups connected by a linear spacer such as ethyne or butadiyne. The sensors chelate an analyte across the acetylene axis of the molecule to stabilize the molecule in an eclipsed rotamer conformation. This conformation causes the sensors to emit a measurable signal.
    Type: Grant
    Filed: May 2, 2000
    Date of Patent: July 1, 2003
    Assignee: The Penn State Research Foundation
    Inventors: Timothy E. Glass, Joseph Raker, Ricardo Moran
  • Patent number: 6342618
    Abstract: Triphenylmethane dyes or colorants with sterically hindered fugitive amine counter ions are provided as durable, storage-stable, and excellent coloring and shading printing inks. Ink compositions are disclosed which provide improvements in long-term storage capabilities, particularly within alkaline environments, extremely effective colorations of cellulose-based substrates, and lower cost over those of the prior art. The preferred dyes or colorants are triphenylmethane polymeric colorants which are capped with cyclic anhydride and the preferred sterically hindered amine counter ions are those based on low molecular weight fugitive tertiary amines, such as N,N-dimethylethanolamine. Compositions comprising water soluble or emulsion resins as diluents for lowered viscosity and lower overall cost are also contemplated. Furthermore, compositions comprising the inventive colorant and other pigments, dyes, surfactants, preservatives, and other colorants are contemplated.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: January 29, 2002
    Assignee: Milliken & Company
    Inventor: Philip G. Harris
  • Patent number: 6342617
    Abstract: Triphenylmethane dyes or colorants with sterically hindered fugitive amine counter ions are provided as durable, storage-stable, and excellent coloring and shading printing inks. Ink compositions are disclosed which provide improvements in long-term storage capabilities, particularly within alkaline environments, extremely effective colorations of cellulose-based substrates, and lower cost over those of the prior art. The preferred dyes or colorants are triphenylmethane polymeric colorants which are capped with cyclic anhydride and the preferred sterically hindered amine counter ions are those based on low molecular weight fugitive tertiary amines, such as N,N-dimethylethanolamine. Compositions comprising water soluble or emulsion resins as diluents for lowered viscosity and lower overall cost are also contemplated. Furthermore, compositions comprising the inventive colorant and other pigments, dyes, surfactants, preservatives, and other colorants are contemplated.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: January 29, 2002
    Assignee: Milliken & Company
    Inventor: Philip G. Harris
  • Patent number: 6342616
    Abstract: Triphenylmethane dyes or colorants with sterically hindered fugitive amine counter ions are provided as durable, storage-stable, and excellent coloring and shading printing inks. Ink compositions are disclosed which provide improvements in long-term storage capabilities, particularly within alkaline environments, extremely effective colorations of cellulose-based substrates, and lower cost over those of the prior art. The preferred dyes or colorants are triphenylmethane polymeric colorants which are capped with cyclic anhydride and the preferred sterically hindered amine counter ions are those based on low molecular weight fugitive tertiary amines, such as N,N-dimethylethanolamine. Compositions comprising water soluble or emulsion resins as diluents for lowered viscosity and lower overall cost are also contemplated. Furthermore, compositions comprising the inventive colorant and other pigments, dyes, surfactants, preservatives, and other colorants are contemplated.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: January 29, 2002
    Assignee: Milleken & Company
    Inventor: Philip G. Harris
  • Patent number: 6331564
    Abstract: The present invention provides a class of chemical compounds useful as efficacious drugs in the treatment of sickle cell disease and diseases characterized by unwanted or abnormal cell proliferation, and in particular inflammatory diseases associated with unwanted cellular proliferation. The active compounds are substituted triaryl methane compounds or analogues thereof where one or more of the aryl groups is replaced with a heteroaryl, cycloalkyl or heterocycloalkyl group and/or the tertiary carbon atom is replaced with a different atom such as Si, Ge, N or P, the compounds inhibit mammalian cell proliferation, inhibit the Gardos channel of erythrocytes, reduce sickle erythrocyte dehydration and/or delay the occurrence of erythrocyte sickling or deformation.
    Type: Grant
    Filed: September 23, 1998
    Date of Patent: December 18, 2001
    Assignee: Ion Pharmaceuticals, Inc.
    Inventors: Carlo Brugnara, Jose Halperin, Emile M. Bellot, Jr., Mark Froimowitz, Richard John Lombardy, John J. Clifford, Ying-Duo Gao, Reem M. Haidar, Eugene W. Kelleher, Falguni M. Kher, Adel M. Moussa, Yesh P. Sachdeva, Minghua Sun, Heather N. Taft
  • Patent number: 6239220
    Abstract: The present invent n provides a method for the preparation of triarylmethyl protecting group reagents. The reagents are prepared from reaction effluent from the cleavage step of oligonucleotide synthetic regimes.
    Type: Grant
    Filed: July 16, 1999
    Date of Patent: May 29, 2001
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Yogesh S. Sanghvi, Zhiqiang Guo
  • Patent number: 6124484
    Abstract: The present invention provides a method for the preparation of triarylmethyl protecting group reagents. The reagents are prepared from reaction effluent from the cleavage step of oligonucleotide synthetic regimes.
    Type: Grant
    Filed: July 17, 1998
    Date of Patent: September 26, 2000
    Assignee: Isis Pharmaceuticals, Inc.
    Inventors: Yogesh S. Sanghvi, Zhiqiang Guo
  • Patent number: 6028103
    Abstract: The present invention provides a class of chemical compounds useful as efficacious drugs in the treatment of sickle cell disease and diseases characterized by unwanted or abnormal cell proliferation. The active compounds are substituted triaryl methane compounds or analogues thereof where one or more of the aryl groups is replaced with a heteroaryl, cycloalkyl or heterocycloalkyl group and/or the tertiary carbon atom is replaced with a different atom such as Si, Ge, N or P. The compounds inhibit mammalian cell proliferation, inhibit the Gardos channel of erythrocytes, reduce sickle erythrocyte dehydration and/or delay the occurrence of erythrocyte sickling or deformation.
    Type: Grant
    Filed: March 19, 1997
    Date of Patent: February 22, 2000
    Assignees: Children's Medical Center Corporation, Ion Pharmaceuticals, Inc.
    Inventors: Carlo Brugnara, Jose Halperin, Emile M. Bellot, Jr., Mark Froimowitz, Richard John Lombardy, John J. Clifford, Ying-Duo Gao, Reem M. Haidar, Eugene W. Kelleher, Falguni M. Kher, Adel M. Moussa, Yesh P. Sachdeva, Minghua Sun, Heather N. Taft
  • Patent number: 6022987
    Abstract: Aryl substituted alkylsilanes represented by the formula I and a preparation method thereof by reacting substituted benzenes represented by the formula II with aryl substituted alkylsilanes represented by the formula III in the presence of Lewis acid catalysts such as aluminum chloride: ##STR1## wherein m, p, and q are 0 or 1, respectively; n and y are 0, 1, or 2, respectively; X.sup.1, X.sup.2, X.sup.3, X.sup.4, and X.sup.5 which are same or different represent hydrogen, fluoro, chloro; R represents C.sub.1 -C.sub.12 alkyl group; provided that if n is 0, m is 0 and if n is 1 or 2, at least two of X.sup.1, X.sup.2, X.sup.3, X.sup.4, and X.sup.5 represent chloro or fluoro group.
    Type: Grant
    Filed: December 23, 1997
    Date of Patent: February 8, 2000
    Assignee: Korea Institute of Science and Technology
    Inventors: Il Nam Jung, Bok Ryul Yoo, Joon Soo Han, Yeon Seok Cho
  • Patent number: 5919846
    Abstract: A novel colorant compound is provided which is the addition product of an organic chromophore having at least one reactive hydroxyl or amine substituent, a polyisocyanate, and a carboxylic acid, sulfonic acid, or salt of either thereof. The polyisocyanate, added in a molar excess relative to the number of such reactive substituents, reacts with the reactive hydroxyl or amine groups to provide terminal isocyanate groups. Subsequently, the carboxylic acid or salt thereof, also added in an amount excessive in relation to the number of terminal isocyanate groups, reacts therewith to from urethane moieties on the colorant. Such a compound provides excellent ink compositions upon dilution and are very soluble within all the standard ink diluents. Furthermore, such colorants provide good jettability, waterfastness, washfastness, and the like, within ink-jet applications on various types of printing substrates.
    Type: Grant
    Filed: February 19, 1998
    Date of Patent: July 6, 1999
    Assignee: Milliken Research Corporation
    Inventors: Raj Batlaw, John W. Miley
  • Patent number: 5804563
    Abstract: The invention is directed to synthetic receptor(s) which comprises a polyfunctional organic template covalently linked to two or more oligomers which may independently be the same or different and may independently be straight chain or branched. The template may be linked to an identifier which uniquely defines the synthetic receptor. The identifier is a stable chemical molecule or a plurality of stable chemical molecules distinguishable and detectable to picomolar levels or may be an oligonucleotide. In an preferred embodiment, the template is covalently linked to a solid support which is linked to an identifier.
    Type: Grant
    Filed: April 8, 1996
    Date of Patent: September 8, 1998
    Assignee: The Trustees of Columbia University in The City of New York
    Inventors: W. Clark Still, Ge Li
  • Patent number: 5419966
    Abstract: A solid support for oligonucleotide synthesis has the structure ##STR1## where CPG represents a controlled pore glass matrix, the wavy line represents a carbon chain covalently linking the NH group with the controlled pore glass matrix, X is 2,2'-dimethoxytrityl or H, and R is alkyl, aryl, arylalkyl, heteroalkyl, or heteroaryl. The dimethoxytrityl group is removed from the solid support by treatment with acid, and the oligonucleotide is built, step-by-step in a conventional synthesizer after attachment of the 3' end of the first oligonucleotide unit to the hydroxyl function connected to the R group.
    Type: Grant
    Filed: July 12, 1993
    Date of Patent: May 30, 1995
    Assignee: MicroProbe Corporation
    Inventors: Michael W. Reed, Rich B. Meyer, Jr., Charles R. Petrie, John C. Tabone
  • Patent number: 5241082
    Abstract: Aromatic trisanhydrides of the formula (I) ##STR1## wherein R is hydrogen, C.sub.1 -C.sub.4 alkyl or aryl are useful for the synthesis of star-branched and star-burst polyester-imides and polyesterimide-amides and as curing agents for epoxy resins, phenolics and polyesters.
    Type: Grant
    Filed: March 11, 1991
    Date of Patent: August 31, 1993
    Assignee: Ciba-Geigy Corporation
    Inventor: Yefim Blyakhman
  • Patent number: 5023325
    Abstract: A reactive dye of the formulaD--U--R).sub.nin which D is the radical of an anthraquinone, phthalocyanine, formazane, azomethine, dioxazine, phenazine, stilbene, triphenylmethane, xanthene, thioxanthone, nitroaryl, naphthoquinone, pyrenequinone or perylenetetracarbimide dye; U is --CO-- or --SO.sub.2 --; R is a radical of the formula ##STR1## Z is sulfatoethyl, .beta.-thiosulfatoethyl, .beta.-phosphatoethyl, .beta.-acetoxyethyl, .beta.-halogenoethyl or vinyl; alk is a polymethylene radical having 1 to 6 C atoms or its branched isomers; Y is hydrogen, chlorine, bromine, fluorine, hydroxyl, sulfato, C.sub.1 -C.sub.4 -alkanoyloxy, cyano, carboxyl, alkoxycarbonyl having 1 to 5 C atoms, carbamoyl or a radical --SO.sub.2 --Z in which Z is as defined above; V is hydrogen or C.sub.1 -C.sub.4 -alkyl which is unsubstituted or substituted by carboxyl, sulfo, C.sub.1 -C.sub.2 -alkoxy, halogen or hydroxyl;or a radical ##STR2## in which Z, alk and Y are as defined above; R.sub.1 is hydrogen or C.sub.1 -C.sub.
    Type: Grant
    Filed: May 11, 1988
    Date of Patent: June 11, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Athanassios Tzikas, Peter Aeschlimann
  • Patent number: 5011955
    Abstract: Synthetic procedures to tetraalkyls, tetraacids and dianhydrides substituted 1,1,1-triaryl-2,2,2-trifluoroethanes which comprises: (1) 1,1-bis(dialkylaryl)-1-aryl-2,2,2-trifluoroethane, (2) 1,1-bis(dicarboxyaryl)-1-aryl-2,2,2-trifluoroethane or (3) cyclic dianhydride or diamine of 1,1-bis(dialkylaryl)-1-aryl-2,2,2-trifluoroethanes. The synthesis of (1) is accomplished by the condensation reaction of an aryltrifluoromethyl ketone with a dialkylaryl compound. The synthesis of (2) is accomplished by oxidation of (1). The synthesis dianhydride of (3) is accomplished by the conversion of (2) to its corresponding cyclic dianhydride. The synthesis of the diamine is accomplished by the similar reaction of an aryltrifluoromethyl ketone with aniline or alkyl substituted or disubstituted anilines. Also, other derivatives of the above are formed by nucleophilic displacement reactions.
    Type: Grant
    Filed: October 10, 1989
    Date of Patent: April 30, 1991
    Inventors: William B. Alston, Roy F. Gratz
  • Patent number: 4912238
    Abstract: Synthetic procedures to tetraalkyls, tetraacids and dianhydrides substituted 1,1,1-triaryl-2,2,2-trifluoroethanes which comprises: (1) 1,1-bis(dialkylaryl)-1-aryl-2,2,2-trifluoroethane, (2) 1,1-bis(dicarboxyaryl)-1-aryl-2,2,2-trifluoroethane or (3) cyclic dianhydride or diamine of 1,1-bis(dialkylaryl)-1-aryl-2,2,2-trifluoroethanes. The synthesis of (1) is accomplished by the condensation reaction of an aryltrifluoromethyl ketone with a dialkylaryl compound. The synthesis of (2) is accomplished by oxidation of (1). The synthesis dianhydride of (3) is accomplished by the conversion of (2) to its corresponding cyclic dianhydride. The synthesis of the diamine is accomplished by the similar reaction of an aryltrifluoromethyl ketone with aniline or alkyl substituted or disubstituted anilines. Also, other derivatives of the above are formed by nucleophilic displacement reactions.
    Type: Grant
    Filed: December 30, 1988
    Date of Patent: March 27, 1990
    Assignee: The United States of America as represented by the United States National Aeronautics and Space Administration
    Inventors: William B. Alston, Roy F. Gratz