Abstract: The present invention comprises a group of related lipid molecules, and methods for their use, that maybe used to treat inflammation and certain inflammation related diseases. The group of related lipid molecules are capable of inhibiting certain enzyme systems including phospholipase A2, and cyclooxygenase-2. The group of related lipid molecules of the invention may be characterized by specific structural characteristics, or by specific biological activity, including inhibition of the previously listed enzymes.

Abstract: Compositions and methods of using conjugated linoleic acid preparations enriched for the t10,c12 and c9,t11 isomers are disclosed. It is found that preparations of conjugated linoleic acid containing a ratio of t10,c12 to c9,t11 of about greater than 1.2:1 are desirable for a wide variety of nutritional, therapeutic and pharmacologic uses.

Abstract: Oils containing a triacylglycerol polyol ester and a non-glycerol polyol ester are described, as well as methods of making such oils. Methods for improving lubrication properties of a vegetable oil also are described.

Abstract: Plants, seeds and oils having a total long chain monounsaturated content of at least about 82% and an erucic acid content of at least about 15% are described. Methods for producing plants having the profiled fatty acid content are also described.

Abstract: The present invention relates to a vegetable oil which is or can be extracted from seeds and in which at least 12% of the triacylglycerol species that constitute the oil have the general formula SMS and at least 25% of the triacylglycerol species have the general formula SMM, wherein the formula gives from left to right the first, second and third fatty acid in the triacylglycerol and S represents a saturated fatty acid and M represents a monoenoic fatty acid. The invention further relates to a meal obtained as the remainder of the process for extracting the oil from seeds, as well as to the seeds containing the oil and the use thereof for the production of progeny plants having seeds which contain the oil.

Abstract: Triglycerides, that have at least two long chain polyunsaturated fatty acids L1 and L2, from which at least one is present for more than 20 wt %, while the weight ratio L1:L2 is at least 2 and which triglycerides also contain at least 2 wt % of saturated fatty acids with 2-12 and/or 20-24 C-atoms, but not more than 10 wt % of saturated fatty acids with 16-18 C-atoms, while at least 5 wt % of the saturated C2-C12 or C20-C24 fatty acid residues is bonded on a triglyceride molecule, wherein at least L1 and/or L2 is present, display a number of advantageous properties (e.g. higher oxidative stability, healthier, lower caloric, structuring properties, digestibility).

Abstract: Edible fat based flakes containing a flavoring system and displaying an excellent oral and textural properties are disclosed that contain i) 0 to 2% moisture ii) 25 to 90 wt % of a fat containing: a vegetable fat with an N20 of more than 50 and 5 to 40 wt % of a fish oil composition, containing w-3 fatty acids so that the w-3 content of the total flavored fat system ranges from 0.1 to 20 wt % iii) 0 to 15% of a flavoring system iv) 0 to 40% of sugar v) 0 to 60 wt % of a filler vi) 0 to 50% of a health component and which flakes have a size of 0.05 mm to 2.5 cm.

Abstract: A mouthguard composition is disclosed, containing (a) from 40 to 80% by weight of a styrene block copolymer, (b) from 20 to 60% by weight of an alicyclic saturated hydrocarbon resin and/or an ester gum, and (c) from 0.1 to 10% by weight of an organopolysiloxane in which at least one of organic groups directly bound to the silicon atom in one molecule thereof is a phenyl group, a methylstyryl group, or an alkyl group having from 7 to 30 carbon atoms. The mouthguard composition is high in durability and impact absorption and is free from sticking to gypsum model or hands and fingers at the time of preparation and adjustment works.

Abstract: The present invention provides a hardstock fat which is suitable for stabilizing a dispersion of a non-fat phase in a triglyceride oil, including liquid margarines, which hardstock fat consists of a mixture of triglycerides, characterized in that, at least two triglycerides having a melting point >55° C. each have a concentration of at least 5 wt. %, the amount of triglycerides having fatty acid residues with a difference in chain length of the longest and the shortest residue of at least four carbon atoms is at least 15 wt. % and the amount of triglycerides with a melting point of 25-55° C. is ≦25 wt. %.

Abstract: A process directed to the preparation of acetals of malondialdehyde by reacting alkylvinyl ethers or esters with ortho formates in the gas phase with a heterogeneous catalyst.

Abstract: The present invention relates to transgenic and non-transgenic plants that produce oil having high levels of saturated fatty acids and medium to high levels of olecic acid. More specifially, the invention relates to a sunflower plant, seed, and the extractable oil having increased stearic acid content and increased oleic acid content relative to the normal sunflower oil level of stearic acid and oleic acid.

Abstract: Administration of alkoxylated acyl glycerine (AAG) containing lower carboxylic acid acyl moieties to mammalian subjects results in increase of lower carboxylate concentration, particularly in the colon, and may be used to treat such disorders as simple colitis, ulcerative colitis, divertive colitis, colorectal cancer, and other diseases of the gastrointestinal tract where lower carboxylates are implicated. The AAG encourage patient compliance due to substantially no odor, even when butyric acid acyl groups are employed.

Abstract: Described herein are novel structured lipids as well as novel mixtures comprising structured lipids. Also described herein are enzymatic methods of forming these structured lipids and mixtures comprising structured lipids. Also described herein are methods of modulating total cholesterol levels, low-density lipoprotein cholesterol, triacylglycerol levels, and/or the ratio of T-helper cells to T-cytotoxic cells in an individual comprising administrating a structured lipid mixture as provided herein. It is further an object to provide a method of modulating weight in an individual comprising administrating a structured lipid mixture as provided herein.

Abstract: Process for the preparation of malondialdehyde-derivatives by reacting vinylesters with orthoesters in the presence of a precious metal catalyst.

Abstract: The present invention provides therapeutic conjugates which comprise a therapeutic compound bound to one to three acyl groups derived from fatty acids. The therapeutic compounds are preferably non-steroidal anti-infiammatory agents which include a carboxylic acid group. The compounds involve the use of tromethamine or ethanolamine derivative to link the acyl groups derived from fatty acids to the therapeutic compounds.

Abstract: The invention relates to plant seeds that contain an oil having an oleic acid content of more than 5% and less than 65% by weight based upon the total fatty acid content, a linoleic acid content of more than 1% and less than 65% by weight based upon the total fatty acid content, a palmitic acid content of more than 20% and less than 40% by weight based upon the total fatty acid content, a stearic acid content of more than 3% and less than 15% based upon the total fatty acid content, and wherein the palmitoleic acid content is less than 4% based upon the total fatty acid content, and the asclepic acid content is less than 4% based upon the total fatty acid content. The invention further relates to the oil that can be obtained from the seeds, the use of that oil and to plants grown from the seeds or producing the seeds.

Abstract: Disclosed are a fatty acid esters composition of a polyglycerine containing more than 70% of a fatty acid monoester which is defined by a specified analysis method, a process for the preparation thereof, a process for the preparation of a highly-purified fatty acid esters composition of a polyglycerine, and a highly-purified fatty acid esters composition of a polyglycerine having an oxirane oxygen concentration of below 100 ppm which is defined by a specified analysis method. The fatty acid esters compositions of a polyglycerine are useful as additives for a variety of food-stuffs, additives for a variety of thermoplastic resins, and as additives for a variety of cosmetics or detergents.

Abstract: By this invention, low calorie fat compositions comprising the use of acylated glycerides are provided. Of particular interest is the use of triglyceride compositions having a at least one acylated fatty acid. Preferably, the acylated fatty acid has a melting temperature above 40° C. The acylated glyceride compositions find use as low calorie fat ingredients in food compositions. The low calorie fat compositions of the present invention demonstrate a caloric value of less than 6.5 kcal/g. Such low calorie fat compositions find use in the preparation of food compositions wherein at least a portion of the fat ingredients have been replaced with a acylated glyceride compositions of the present invention.

Abstract: 15-HETE derivatives with enhanced metabolic stability and methods of their use for treating dry eye are disclosed.

Abstract: The present invention relates to a wax mixture comprising a) 10-80% by weight of partial esters of polyols with carboxylic acids or carboxylic acid mixtures having a chain length of C16-C36; b) 0-30% by weight of partial esters of polyols with polybasic carboxylic acids having a chain length of C4-C36; and c) 20-90% by weight of alkaline earth metal soaps of the abovementioned carboxylic acids or carboxylic acid mixtures, with the proviso that 1,2-ethanediol and 1,3-butanediol are excluded. The wax mixtures are highly suitable for the preparation of solvent pastes as a single component or in combination with synthetic, natural or semi-synthetic wax-like products, as lubricants or release agents in plastic or metal processing, and for the preparation of microfine wax powders.

Abstract: The present invention relates to a process for preparing calorie cooking and frying oils, containing nondigestable polyol polyesters, and having improved color and improved stability against hydrolysis during frying. The process comprises, as a first step, treating a crude polyol polyester with an ion exchange ligand in an aqueous phase to convert diavalent metal soaps present in the crude polyol polyester to monovalent soaps. The monovalent soaps and ion exchange ligands are then removed from the treated polyol polyester to provide a cooking and frying oil which contains less than about 550 ppb divalent metal ions. Said oil, when further processed according to conventional industry standards will have a free fatty acid content of less than about 500 ppm. Preferably, the cooking and frying oils prepared according to the process of the present invention will further have a Lovibond red color of less than about 6, preferably less than about 4.

Abstract: The present invention to provide a process for conditioning hair and skin which comprise contacting the skin or hair with an effective conditioning concentration of a of the reaction product of meadowfoam oil and an ester selected from the group consisting of beeswax, jojoba oil, carnauba wax, and candelilla wax.

Abstract: Disclosed is a new structural class of amphiphilic molecules which incorporate a hydrophilic material or polymer attached, at spatially distinct sites, to at least two hydrophobic residues. Certain of the amphiphilic molecules comprise a plurality of hydrophobic moieties. All such amphiphilic molecules have a common structural motif and, in contact with water, display surface activity and self-assemble into multimolecular aggregates and liquid crystalline phases. Also disclosed are enhanced stability liposomes that incorporate such amphiphilic molecules via unique interactions, and methods of using such formulations in a variety of applications including drug delivery, nutrition, bio-diagnostics, cosmetics, blood products and related applications.

Abstract: Oral and dental care compositions comprising sorbitol esters obtained by transesterification of optionally oxalkylated sorbitol with fatty acid methyl esters or fatty acid triglycerides and optionally oxalkylation of the reaction products obtained by transesterification with fatty acid methyl esters.

Abstract: A triacylglycerol containing oil having a 1,3-dierucoyl 2-oleoyl glycerol (EOE) content of at least 50% is described. Plants for producing an oil having a high EOE content are also described.

Abstract: Described are reduced calorie edible plastic fat compositions based on mixtures of triglycerides being various combinations of short (C2 to C4), saturated long (C16 to C22), and monounsaturated long (C16 to C22) chain fatty acid residues, and the use of such compositions in edible compositions such as shortenings and margarines.

Abstract: Disclosed are a fatty acid esters composition of a polyglycerine containing more than 70% of a fatty acid monoester which is defined by a specified analysis method, a process for the preparation thereof, a process for the preparation of a highly-purified fatty acid esters composition of a polyglycerine, and a highly-purified fatty acid esters composition of a polyglycerine having an oxirane oxygen concentration of below 100 ppm which is defined by a specified analysis method. The fatty acid esters compositions of a polyglycerine are useful as additives for a variety of food-stuffs, additives for a variety of thermoplastic resins, and as additives for a variety of cosmetics or detergents.

Abstract: Randomized fats from triglycerides are disclosed which have a fatty acid composition of: 20-50% C18:0, 30-60% C18:1, 5-15% C16:0 and 0-15% C18:2. The fats display a solid fat content at the temperatures indicated of: N10=10-30, N20=8-20, N30=5-8 and N35<5.

Abstract: Mixtures of dimeric and trimeric fatty acid C1-4 alkyl esters and processes for their preparation comprising either A) epoxidizing an unsaturated or partially hydrogenated fatty acid glyceride; B) transesterifying the epoxidized glyceride with a C1-4 alkanol to obtain epoxidized fatty acid C1-4 alkyl esters; and C) ring opening and dimerizing the epoxidized fatty acid C1-4 alkyl esters; or A) transesterifying an unsaturated or partially hydrogenated glyceride with a C1-4 alkanol to obtain olefinically unsaturated fatty acid C1-4 alkyl esters; B) epoxidizing the unsaturated fatty acid C1-4 alkyl esters; and C) ring opening and dimerizing the epoxidized fatty acid C1-4 alkyl esters.

Abstract: Reduced calorie fat mimetics comprising fatty acid-esterified alkoxylated polyol compositions having an average number of oxyalkylene groups per molecule of no more than 5 and from 5 percent to 39 percent primary hydroxyl groups based on the total amount of hydroxyl groups on the molecule. These reduced calorie fat mimetics are prepared by alkoxylating a polyol such that the average number of oxyalkylene groups per molecule is no more than 5, and subsequently esterifying with fatty acids. The reduced calorie fat mimetics can be synthesized to mimic the properties of the natural fats which are replaced in numerous food products. The fat mimetics are partially digestible thus obviating undesirable gastrointestinal side effects.

Abstract: The present invention relates to a series of “reconstituted meadowfoam oils”. The term reconstituted as used heron refers to a process in which meadowfoam oil and one or more oils of natural origin are transesterfied under conditions of high temperature and catalyst to make a “reconstituted product” having an altered alkyl distribution and consequently altered chemical and physical properties. The present invention deals with the reaction of meadowfoam oil and beeswax, carnauba wax, candellia wax, and jojoba oil.

Abstract: The present invention discloses a microbial polyunsaturated fatty acid(PUFA)-containing oil with a high triglyceride content and a high oxidative stability. In addition, a method is described for the recovery of such oil from a microbial biomass derived from a pasteurised fermentation broth, wherein the microbial biomass is subjected to extrusion to form granular particles, dried and the oil then extracted from the dried granules using an appropriate solvent.

Abstract: Compounds of structure (I), and when for use in therapy: where R1 is an acyl group derived from a C16-30 fatty acid with two or more cis or trans double bonds and particularly an n-6 or n-3 series EFA or conjugated linoleic acid, or columbinic acid, or parinaric acid and R2 is as R1 the same or different, or any other nutrient, drug or other bioactive residue released as the active in the body and R3 is either hydrogen, fully hydrocarbon, or containing heteroatoms, preferably an alkyl group particularly a C1-C4 alkyl group.

Abstract: The invention relates to polyglycerol partial esters of saturated or unsaturated, linear or branched fatty acids and polyfunctional carboxylic acids, which are obtainable by esterification of a polyglycerol mixture with saturated or unsaturated, linear or branched fatty acids having 12 to 22 carbon atoms and polyfunctional carboxylic acids having 4 to 54 carbon atoms and a mean functionality of from 2 to 2.4, the degree of esterification of the polyglycerol mixture being between 30 and 75%.

Abstract: Compositions and methods of using conjugated linoleic acid preparations enriched for the t10,c12 and c9,t11 isomers are disclosed. It is found that preparations of conjugated linoleic acid containing a ratio of t10,c12 to c9,t11 of about greater than 1.2:1 are desirable for a wide variety of nutritional, therapeutic and pharmacologic uses.

Abstract: A fat is provided hich is substantially free of trans saturated fatty acid residues and suitable for use in the preparation of a spread, which consists of an interesterified mixture of 30-90% of high lauric rapeseed oil, and 10-70% of an oil A comprising at least 40% of saturated fatty acid residues of which saturated fatty acid residues at least 80% are C16-C18 fatty acid residues and at most 60% are C16 fatty acid residues. The fat is used for preparing margarine fats and spreads. It provides low-trans and trans-free spreads with improved properties, while problems caused by slow crystallization are avoided.

Abstract: The present invention provides a lubricating oil or a lubricating oil additive, particularly suitable for a R-134a (1,1,1,2-tetrafluoroethane) or R-134 (1,1,2,2-tetrafluoroethane) refrigerant, consisting of a compound (X) that can be prepared by esterification of a polyoxyethoxylated glycerol with at least one polycarboxylic acid compound having from 2 to 20 carbon atoms, preferably from 4 to 13 carbon atoms, and at least one monocarboxylic acid compound having from 2 to 20 carbon atoms, preferably from 6 to 13 carbon atoms.

Abstract: The present invention relates to the use of ethoxylated fatty acid esters as self-emulsifiable compounds particularly useful for the preparation of phytosanitary treatment products or as drugs for veterinary or human use. According to the invention, said fatty acid esters comprise a total number of ethylene oxide molecules such that the HLB value (hydrophilic-lipophilic balance) of said compounds is comprised between about 4 and about 10, preferably between about 5 and about 9. Said ethoxylated fatty acid esters form in an original way self-emulsifiable components without requiring any other surfactant, and they are biodegradable and capable of dissolving active principles which are little or non water-soluble.

Abstract: The present invention is directed to free radical polymers, which contain a meadowfoam ester group as one of the functional groups polymerized. The compounds of the invention are prepared by the free radical polymerization of a novel meadowfoam monomer having a reactive vinyl group and a number of other free radical polymerizable reactants. The unique structure of the meadowfoam results in polymers with oxidative stability heretofore unattainable.

Abstract: Alpha-fluorinated alkynoic acids and pharmaceutical compositions containing these compounds are provided, which are useful for the treatment and prevention of seizures such as are associated with epilepsy. The compounds of the invention exhibit reduced side effects, relative to valproic acid, with regard to sedation and teratogenic potential.

Abstract: Dry fractionation process where a fat soluble derivative of a high molecular weight polymer, preferably an ester of a polysaccharide is used as crystal habit modifier.

Abstract: Provided are a flame-retardant polycarbonate resin composition capable of being formed into moldings having good impact resistance, high strength and good thermal stability that are intrinsic to polycarbonate resins and having good antistatic properties and good flame retardancy, and also injection moldings of the composition. The composition comprises 100 parts by weight of a resin or resin mixture of (A) from 50 to 100% by weight of a polycarbonate resin and (B) from 0 to 50% by weight of a styrenic resin, from 1 to 50 parts by weight of (C) a flame retardant, and from 0.1 to 5 parts by weight of (D) an anionic antistatic agent, and has a sodium sulfate content of at most 0.05% by weight. Optionally, the composition may contain (F) a fluoro-olefinic resin, (G) a rubber-like elastomer, and (H) an inorganic filler.

Abstract: Liquid oils with a SAFA-content of less than 5 wt % can be obtained by conversion of a fatty compound (A), preferably having a SAFA-level of more then 5 wt %, with a reactant (B), capable of forming different reaction products of the non-triglyceride type (C.sub.1, C.sub.2 etc.) having a different melting point and/or different solubility in compound (A); the SAFA-level of the end product can be controlled by separating the precipitate of the higher melting more saturated reaction-products (C.sub.1, C.sub.2 etc.) from the rest of the reaction mixture.

Abstract: Iodinated fatty acid esters, iodinated fatty acids and fluid pharmaceutical-grade stable derivatives thereof are produced by iodohydrination in an organic medium using alkylsilylated derivatives, such as trimethylsilyl chloride or trimethylchlorosilane, that react with an alkaline iodide such as sodium iodide, whereafter hydroiodic acid is formed in situ by exposure to water and the hydroiodic acid is reacted with fatty acid esters and particularly rapeseed oil fatty acid methyl esters that may be used as a biofuel for gasoline engines to provide a low-cost product, and are used therapeutically, in particular for treating goitre linked to iodine deficiency.

Abstract: A peanut line and seed and oil products derived therefrom wherein the seed has an oleic acid content of from about 74% to about 84% and a linoleic acid content of from about 2% to about 8%, each based upon the total fatty acid content of the seed, and a ratio of the amount of oleic acid to linoleic acid in the seed of from about 9:1 to about 42:1.

Abstract: The present invention relates to the use of ethoxylated fatty acid esters self-emulsifiable compounds particularly useful for the preparation of phytosanitary treatment products or as drugs for veterinary or human use. According to the invention, said fatty acid esters comprise a total number of ethylene oxide molecules such that the HLB value (hydrophilic-lipophilic balance) of said compounds is comprised between about 4 and about 10, preferably between about 5 and about 9. Said ethoxylated fatty acid esters form in an original way self-emulsifiable components without requiring any other surfactant, and they are biodegradable and capable of dissolving active principles which are little or non water-soluble.

Abstract: Two new forms of prodrug for phenylacetate, of even congeners of phenylalkanoic acid and phenylalkenoic acids, which are the phenylalkanoic or phenylalkenoic esters of glycerol, or the ethyl esters of phenylalkanoic acid or phenylalkenoic acids. These forms of the drugs provide a convenient dosage form of the drugs. The prodrugs of the invention are useful to treat patients with diseases of nitrogen accumulation, patients with certain .beta.-hemoglobinopathies, anemia, and cancer.

Abstract: An endogenous oil extracted from Brassica seeds is disclosed that contains, after crushing and extraction, greater than 86% oleic acid and less than 2.5% .alpha.-linolenic acid. The oil also contains less than 7% linoleic acid. The Brassica seeds are produced by plants that contain seed-specific inhibition of microsomal oleate desaturase and microsomal linoleate desaturase gene expression. Such inhibition can be created by cosuppression or antisense technology. Such an oil has a very high oxidative stability in the absence of added antioxidants.

Abstract: The present invention provides compositions and methods for protecting cells from injury due to intrinsic membrane lysis, oxidation and/or invasion by destructive agents. Even more particularly, the present invention provides compositions and methods for treating or prophylactically inhibiting phospholipase mediated injury, injury due to oxidation, and inflammation. In a very specific sense, this invention provides compositions and methods of making these compositions that are inhibitors of phospholipase.

Abstract: The present invention deals with the composition of matter and the utilization of certain novel sorbitol guerbet esters which are prepared by the reaction of a guerbet acid and a sorbitol as emulsifiers.