Abstract: Disclosed is a hair colouring composition containing amino acids with at least a pKa greater than 10, oxidative dyes, and acetylaspartic acid or salts thereof. The compositions according to the invention do not contain ammonia or ethanolamine, do not damage the hair, guarantee shine and combability, and also cover white hair and withstand blue light.

Abstract: A modified drilling fluid comprising a drilling fluid and the reaction product(s) of a polyalkylene polyamine, fatty acid, and alkylene carbonate, and methods of making and using the same.

Abstract: The present invention provides a method for acylating one or more amino groups of a peptide where the acylation reaction is to be performed in an aqueous mixture containing less than 10% w/w aprotic polar solvent.

Abstract: The present invention relates to an aqueous microemulsion, comprising a) one or more liquid carboxylic acid esters, b) one or more water-soluble salts having one or more cations, preferably selected from the group comprising sodium, potassium, calcium, magnesium, and ammonium, c) one or more salts of sulphosuccinic acid ester, d) one or more nonionic surfactants selected from alkoxylated sorbitan ester and alkoxylated vegetable oil, and e) one or more boosters.

Abstract: Substituted saccharide compounds, dental compositions comprising substituted saccharide compounds, and methods of using dental compositions are described. In one embodiment, the substituted saccharide amide compound comprises a hydrophobic group and at least one free-radically polymerizable group with the proviso that the hydrophobic group is not bonded to the ethylenically unsaturated carbon atom of the free-radically polymerizable group. The hydrophobic group is typically bonded to a nitrogen atom of a saccharide amine residue or a carbonyl moiety of saccharide amide residue.

Abstract: N-fatty acid-amino acid conjugates and J2 prostanoid-amino acid conjugates are disclosed along with methods for making such conjugates and methods of using these conjugates in the treatment of conditions that involve dysfunctional lipid metabolism, insulin sensitivity, glucose homeostasis, and/or inflammation.

Abstract: The invention is a catalyst, the use of the catalyst and a method of using the catalyst in the formation of a compound with an amide bond. The catalyst is an HOBT derivative having the following formula (1): where R1 is a group bearing a positive charge at pH 5-7; where Y is a bond or a substituted or unsubstituted alkylene chain containing 1-10 carbon atoms and 0-2 heteroatoms selected from the group consisting of N, S and O; and where X is a linker group selected from —CO— or —SO2—. In the method, an amine, a carboxylic acid, an amide coupling agent and a catalyst of formula (1) are reacted for a time sufficient to produce an amide bond between the amine and the carboxylic acid. Thereafter, the compound containing the amide bond is isolated.

Abstract: Oleamide is an endogenous fatty acid primary amide that possesses sleep-inducing properties in animals and has been shown to effect seratonergic systems and block gap junction communication in a structurally specific manner. Certain agents can serve both as an oleamide agonist and as an inhibitor of fatty acid amide hydrolase. Fatty acid amide hydrolase is responsible for the rapid inactivation of oleamide in vivo. The structural features of oleamide required for inhibition of gap junction-mediated chemical and electrical transmission in rat glial cells are defined. Effective inhibitors fall into two classes of fatty acid primary amides of which oleamide and arachidonamide are the prototypical members. Of these two, oleamide constitutes the most effective and its structural requirements for inhibition of the gap junction are well defined.

Abstract: The present invention aims to provide a novel sphingosine analogue, which is useful as an intermediate for syntheses of novel lipid derivatives such as sphingolipid derivatives and the like that can regulate the effects of sphingolipid. The present invention relates to a sphingosine analogue represented by the general formula (I) described below. In the formula, as for Q1, Q2 and Q3, Q1 and Q2, which are the same or different each other, are hydrogen, alkyl groups having 1-4 of carbon atoms, acyl groups having 2-5 of carbon atoms, or protecting groups of the amino group, and Q3 is a hydrogen or a protecting group of the hydroxyl group; or Q2 and Q3 make up an isopropylidene group and Q1 is a hydrogen or a protecting group of the amino group. Q4 and Q5, which are the same or different each other, are hydroxyl groups, acyl groups having 2-5 of carbon atoms, —O—Q6, or hydrogen; or Q4 and Q5 make up a covalent bond. Q6 is a protecting group of the hydroxyl group.

Abstract: The present invention is directed to free radical polymers, which contain a meadowfoam ester group as one of the functional groups polymerized. The compounds of the invention are prepared by the free radical polymerization of a novel meadowfoam monomer having a reactive vinyl group and a number of other free radical polymerizable reactants. The unique structure of the meadowfoam results in polymers with oxidative stability heretofore unattainable.

Abstract: The invention relates to fatty acids conjugated to amino acids and their derivatives that elicit the production and/or release of plant volatiles compounds which attract and/or retain beneficial insects and deter herbivorous insect feeding. These conjugates also induce plants to increase production of pharmacologically important compounds such as taxol, increase fragrance of flowers, and increase production of plant essential oil. The invention also relates to methods for isolating the compounds from herbivorous insect oral secretions and to chemically synthesizing the compounds and their active derivatives.

Abstract: At least 5, preferably at least 30, in particular about 50, percent by weight of the alkali metal salts and/or triethanolamine salts of alkanoylamidocarboxylic acids of the general formula ##STR1## R.sup.1 denotes an alkanoyl or an alkanesulfonyl radical, each having 6 to 20 carbon atoms, ##STR2## R.sup.4 denotes a hydrogen atom; m is 2;n is 0 or 1, andz denotes an integer from 0 to 3;are used as antifoams in corrosion-inhibiting metal working compositions.

Abstract: Fluorinated diesters useful for imparting repellency of low surface tension fluids to thermoplastic polymers of formulaeR.sub.f --O--C(O)--(CH.sub.2).sub.n --C(O)--O--R.sub.1 ;R.sub.f --O--C(O)--CH.sub.2 --CH(R.sub.2)--C(O)--O--R.sub.f ;a mixture of R.sub.f --O--C(O)--(CH.sub.2).sub.n --C(O)--O--R.sub.1,R.sub.f --O--C(O)--(CH.sub.2).sub.n --C(O)--R.sub.f, and R.sub.1 --O--C(O)--(CH.sub.2).sub.n --C(O)--O--R.sub.1 ;and [F(CF.sub.2).sub.x CH.sub.2 CH.sub.2 --S--CH.sub.2 ].sub.2 --C--[CH.sub.2 --O--C(O)--C.sub.17 H.sub.35 ].sub.2 ;wherein R.sub.f is F(CF.sub.2).sub.x --(CH.sub.2).sub.m wherein x is 4 to 20 and m is 2 to 6, or F(CF.sub.2).sub.x --SO.sub.2 N(R.sub.3)--R.sub.4 wherein x is 4 to 20; R.sub.1 is a saturated aliphatic hydrocarbon with an average carbon chain length of 12 to 66 carbons; R.sub.2 is a saturated or unsaturated hydrocarbon with 1-20 carbon atoms; R.sub.3 is an alkyl radical having 1 to 4 carbon atoms; R.sub.

Abstract: According to the invention, an improved class of amphoteric surfactant having improved surfactant properties characterized as mild and environmentally safe has been provided comprising compounds of the formula: ##STR1## The amphoteric surfactant of the subject invention have at least two hydrophobic moieties and at least two hydrophilic groups per molecule and are useful as emulsifiers, detergents, dispersants and solubilizing agents.

Abstract: .alpha.-Amino-substituted acetic acids or acid salts of formula ##STR1## where R represents a hydrogen atom or an alkyl or alkoxy group X represents a hydrogen atom, an alkali metal or alkaline-earth metal or an ammonium residue characterized in that they are totally free of haloacetic acid and alkali metal halide. They are capable of being obtained by reaction, under hot conditions, of glyoxal, or of a precursor of glyoxal, with a secondary amine or one of its salts of formula ##STR2## where R represents a hydrogen atom or an alkyl or alkoxy group, optionally followed by hydrolysis. They may be used as amphoteric surface-active agents for the manufacture of cosmetic compositions.

Abstract: The process of the invention is directed to the synthesis of cationic type surfactant compounds consisting of natural basic-character amino acids, and any of their homologs, suitably modified for the purpose of obtaining products having specific applications as antimicrobial (biocidal) agents. The process comprises a first step of esterification of an amino acid, and a second step of the condensation of a fatty acid chloride with an esterified amino acid derivative. Nontoxic reaction media and catalysts are used, and a final product free from impurities is obtained. The cost of the process of the invention is reduced from prior art processes due to the use of cheaper starting materials and simpler equipment.

Abstract: The present invention deals with novel novel amido amines amphoteric surfactants which contain ether functionalities. The utility for these novel polymers is as softening, anti-tangle, and conditioning agents for use in personal care, textile and related applications. The properties of these novel amphoteric polymeric compositions which makes them well suited for these applications is the fact that they are substantive to fibers, hair and skin and also very mild to the skin and eyes.

Abstract: It has been found that certain combinations of substituted imidazoline-based amphoterics and quaternary ammonium compounds show markedly reduced irritation profile in addition to providing excellent cleaning detergency. Moreover, it has further been found that certain substituted imidazoline amphoteric surfactants in combination with didecyl dimethyl ammonium chloride (DIDAC) show unexpected synergistic irritation reduction compared to that observed when the quaternary is an ADBAC type. This allows the formulation of disinfectants and sanitizers with the favored antimicrobial agent while at the same time affording the optimum reduction in irritation potential.

Abstract: A method for the synthesis of amphoteric surfactants by the reaction of amines with chloroacetic acid or its salts in aqueous solution at an elevated temperature, consists of reacting compounds of the general formula ##STR1## with chloroacetic acid at temperatures ranging from 115.degree. to 180.degree. C., until the chloroacetic acid content is less than 10 ppm.

Abstract: The present invention relates to new lupane dervivatives of the general formula: ##STR1## to their salts, to their preparation and to the pharmaceutical compositions which contain them.

Abstract: The present invention relates to novel polyether-substituted compounds of imides and their use as surface-active agents.

Abstract: Chemical synthesis of amido acids, and their conversion to amido acid phenyl ester sulfates for use as bleach activators, starting from carboxylic acids and lactams.

Abstract: The process described relates to the preparation of aqueous betaine solutions by reaction of a tertiary amine with an .omega.-monohalocarboxylic acid, preferably monochloroacetic acid, and an alkali metal hydroxide in the presence of water, which solutions are said to be highly pure particularly in respect of the tertiary starting amine and .omega.-monohalocarboxylic acid. This is achieved by first reacting the three reaction components in a certain molar ratio with the aim of obtaining a betaine solution which comprises only a tolerated amount of starting amine. This aqueous betaine solution is then treated with a sulfonating agent, preferably with an alkali metal sulfite, alkali metal pyrosulfite or alkali metal bisulfite, for conversion of the .omega.-monohalocarboxylic acid present into the corresponding sulfocarboxylic acid, which is not troublesome. The process described is simple to carry out and leads to the highly pure aqueous betaine solutions mentioned.

Abstract: A method is disclosed for the preparation of flowable, aqueous dispersions, which contain 10 to 30% by weight of betaines of the general formula ##STR1## wherein R.sup.1 is a linear alkyl group with at least 16 carbon atoms or the R.sup.4 CONH(CH.sub.2).sub.x -- group, in which R.sup.4 CO is an acyl group derived from a saturated, linear fatty acid with at least 16 carbon atoms and x=2 or 3,R.sup.2, R.sup.3 are the same or different and in each case represent an alkyl group with 1 to 4 carbon atoms,y is 1, 2 or 3,by quaternizing a tertiary amine of the general formulaR.sup.1 --NR.sup.2 R.sup.3with .omega.-halogenalkylcarboxylic acids X(CH.sub.2).sub.y COOY or their salts (X=halogen group, Y=hydrogen, alkali or ammonium) in an aqueous or alcoholic, aqueous solution at elevated temperature. Anionic surfactants are added to the reaction mixture before the quaternization reaction in such amounts, that the ultimate dispersion contains 1 to 10% by weight of anionic surfactants.

Abstract: The present invention relates to the compounds of formula (I): ##STR1## in which: R.sub.1 and R.sub.2, which are identical or different, denote a methyl or ethyl radical;R.sub.3 denotes a methyl, ethyl or hydroxyethyl radical;A denotes a ##STR2## radical or ##STR3## R denotes H or CH.sub.3 ; X denotes Cl.sup.-, BR.sup.-, I.sup.-, CH.sub.3 OSO.sub.3.sup.-, CH.sub.3 SO.sub.3.sup.-, ##STR4## p and q, which are identical or different, denote integers such that 1.ltoreq.p.ltoreq.15, 0.ltoreq.q.ltoreq.13 and 2.ltoreq.p+q.ltoreq.20;n denotes an integer equal to 2 or 3;m denotes 0 or 1, and m+q.noteq.0;as well as the salts from neutralization by bases, their preparation process and their utilization as an additive in compositions for treatment of keratinous materials.

Abstract: Amphiphilic lipid compound having the formula: ##STR1## in which: R.sub.1 denotes a C.sub.7 -C.sub.21 alkyl or alkenyl radical,R.sub.2 denotes a saturated or unsaturated C.sub.7 -C.sub.31 hydrocarbon radical,COA denotes a group chosen from the following groups:a) COOM, M being H, Na, K, NH.sub.4 or a substituted ammonium ion derived from an amine,b) ##STR2## B being a radical derived from mono- or polyhydroxylated primary or secondary amines and R denoting a hydrogen atom or a methyl, ethyl or hydroxyethyl radical,c) ##STR3## Q denoting a substituted aminoalkyl or ammonioalkyl radical and R having the meaning indicated for b), andd) COOZ, Z representing the residue of a C.sub.3 -C.sub.7 polyol, and a process for its preparation.Cosmetic or dermopharmaceutical composition comprising the said compound and especially an aqueous dispersion of liposomes.