Halogen Or Additional Oxygen Containing (e.g., Isocyanate Containing, Etc.) Patents (Class 554/55)
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Publication number: 20140027354Abstract: The invention concerns a process for enriching an iron mineral from a silicate containing iron ore by inverse flotation comprising the addition of a collector or collector composition comprising at least one of the compounds of formulae RC(O)N(Z—O—X-NH2)2 (Ia); RC(O)N(Z-O-X-NH2)2H+ Y? (Ib); in which X is an aliphatic alkylene group containing 2 to 6 carbon atoms; Z is an aliphatic alkylene group containing 2 to 6 carbon atoms; Y? is an anion; and R is a saturated or unsaturated, linear or branched, aliphatic or aromatic moiety having between 7 and 23 carbon atoms. The invention also relates to the novel compounds according to formulae (Ia) and (Ib), compositions comprising said compounds and the use of compounds and formulations as collectors for enriching of iron mineral.Type: ApplicationFiled: April 4, 2012Publication date: January 30, 2014Applicant: BASF SEInventors: Christian Bittner, Joerg Nieberle, Bernhard Ulrich von Vacano, Alexsandro Berger, Roland Boehn, Guenter Oetter
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Publication number: 20120093875Abstract: Aminocyclitol compounds and uses thereof as pharmaceutical compositions for the treatment of diseases associated with alterations in iNKT cells, more specifically autoimmune diseases, cancer, infections caused by pathogenic microorganisms or inflammatory diseases. Furthermore, the invention relates to the process for obtaining said compounds.Type: ApplicationFiled: September 20, 2011Publication date: April 19, 2012Inventors: Amadeo Llebaria Soldevilla, Carmen Bedia Girbés, Youssef Harrak Serifi, Angel Raul Castaño Garcia, Carolina Mercedes Barra Quaglia, Antonio Delgado Cirilo
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Publication number: 20100279870Abstract: A method of producing an amidoamine alkoxylate is disclosed that involves reacting a triglyceride, a carboxylic acid, or a combination of triglyceride and carboxylic acid with an alkyleneamine to produce an amidoamine and alkoxylating the amidoamine with an alkylene oxide. Also disclosed are amidoamine alkoxylate compositions and their use in agricultural formulations.Type: ApplicationFiled: December 19, 2008Publication date: November 4, 2010Applicant: Huntsman Petrochemical LLCInventors: Alan J. Stern, Curtis M. Elsik
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Patent number: 7811548Abstract: The invention generally relates to novel fluorescent phospholipid compounds and compositions comprising these compounds.Type: GrantFiled: May 11, 2009Date of Patent: October 12, 2010Assignee: Cellectar, Inc.Inventors: Anatoly Pinchuk, Jamey P. Weichert, Marc Longino, Irawati Kandela, William R. Clarke
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Patent number: 7161016Abstract: Novel analogs of arachidonylethanolamide are presented which have higher affinities for the cannabinoid CB1 and/or CB2 receptor sites. Further, most of the analogs exhibit greater metabolic stability than arachidonylethanolamide. The improved receptor affinity and selectivity and/or greater metabolic stability make these analogs therapeutically useful as medications for relief of pain caused by cancer and nausea caused by chemotherapy, as well as for peripheral pain. The compounds may also be useful as oral and topical contraceptives, in suppression of the immune system, enhancement of appetite and in treatment of psychomotor disorders, multiple sclerosis and hypertension.Type: GrantFiled: November 24, 1999Date of Patent: January 9, 2007Assignee: University of ConnecticutInventors: Alexandros Makriyannis, Atmaram Khanolkar, Andreas Goutopoulos
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Patent number: 6835831Abstract: Disclosed is a method of preparing a composition comprising a compound represented Structural Formula (I): The method comprises the step of reacting an aldehyde compound R10CHO with an isonitrile compound represented by Structural Formula (II):Type: GrantFiled: November 26, 2002Date of Patent: December 28, 2004Assignee: Genzyme CorporationInventor: Bradford H. Hirth
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Patent number: 6756504Abstract: The invention relates to compounds of the general formula (I), as defined, and to pharmaceutical compositions containing them. The compounds of formula (I) are inhibitors of various lipid-related enzymes. They can be used in reducing accumulation of sphingolipids and thus in the treatment of lipid storage diseases. The compounds of formula (I) can also be used for the treatment of cancerous diseases and for killing of wild type and drug-resistant cancer cells.Type: GrantFiled: October 17, 2002Date of Patent: June 29, 2004Assignee: Yissum Research Development Company of the Hebrew University of JerusalemInventors: Arieh Dagan, Shimon Gatt
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Patent number: 6747164Abstract: The present invention relates to the use of an amino compound, which is an esteramine or an amidoamine surfactant with improved biodegradability, as an adjuvant for agrochemically active compounds such as pesticides or fertilizers. The adjuvant has Formula (I) where R1 is an aliphatic group containing 7-22 carbon atoms; EO is an ethyleneoxy group; Y is 0 or NH; R2 and R3 is independently CH2CH2OH or an alkyl group with 1-5 carbon atoms, preferably 1-3 carbon atoms; n is a number between 0-10; x is a number 0-1 provided that when Y is O, then x is 1, and when Y is NH, then x is O; and m is a number 2-6, preferably 2-3, provided that when Y is NH, then m is 3-6, preferably 3; or an adduct obtained by reacting one mole of the compound with 1-5 moles of an alkylene oxide having 2-3 carbon atoms.Type: GrantFiled: March 25, 2003Date of Patent: June 8, 2004Assignee: Akzo Nobel N.V.Inventors: Bodil Gustavsson, Burkhard Weuste
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Patent number: 6506710Abstract: A method for controlling the rheology of aqueous systems, particularly for those intended for underground use, includes injecting an aqueous viscoelastic fluid containing a surfactant gelling agent into the system. The viscoelastic surfactant composition of the invention comprises, as a gelling agent, at least one fatty aliphatic amidoamine oxide in a glycol solvent. The composition also maintains the levels of free fatty acid and free amine within critical parameters in order to achieve superior performance. The additives may be incorporated in the viscoelastic fluid to tailor its use in stimulation fluids, drilling muds, fracture fluids, and in applications such as permeability modification, gravel packing, cementing, and the like.Type: GrantFiled: April 20, 2000Date of Patent: January 14, 2003Assignee: Akzo Nobel N.V.Inventors: Michael D. Hoey, Ralph Franklin, Douglas M. Lucas, Maurice Dery, Randy E. Dobson, Michael Engel, James F. Gadberry, Ramanair S. Premachandran, Glenda Del Carmen Vale
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Patent number: 6437032Abstract: A novel compound bearing urethane linkage of formula as shown herebelow, which is an adduct of ricinoleic ester and isocyanate, useful as a plasticizer for polyvinylchloride (PVC) and a process for the preparing the compound bearing urethane linkage by reacting fatty acid esters bearing hydroxyl groups with an organic isocyanate in the presence of a catalyst at a temperature in the range of 30°-100° C.Type: GrantFiled: September 22, 1998Date of Patent: August 20, 2002Assignee: C.S.I.R.Inventors: Srinivasan Subbagiri Ramaswamy Iyengar, Raut Kundalik Ganpat, Saxena Prabhat Kumar, Sivaram Swaminathan
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Patent number: 6251931Abstract: Oleamide is an endogenous fatty acid primary amide that possesses sleep-inducing properties in animals and has been shown to effect seratonergic systems and block gap junction communication in a structurally specific manner. Certain agents can serve both as an oleamide agonist and as an inhibitor of fatty acid amide hydrolase. Fatty acid amide hydrolase is responsible for the rapid inactivation of oleamide in vivo. The structural features of oleamide required for inhibition of gap junction-mediated chemical and electrical transmission in rat glial cells are defined. Effective inhibitors fall into two classes of fatty acid primary amides of which oleamide and arachidonamide are the prototypical members. Of these two, oleamide constitutes the most effective and its structural requirements for inhibition of the gap junction are well defined.Type: GrantFiled: April 19, 2000Date of Patent: June 26, 2001Assignee: The Scripps Research InstituteInventors: Dale L. Boger, Norton B. Gilula, Richard A. Lerner, Benjamin F. Cravatt
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Patent number: 6239183Abstract: A method for controlling the rheology of aqueous systems, particularly for those intended for underground use, includes injecting an aqueous fluid containing a surfactant gelling agent into the system. The surfactant gelling agents are, for example, fatty aliphatic amidoamine oxides, salts of an alkoxylated monoamine with an aromatic dicarboxylic acid, and salts of an alkyldiamine with an aromatic dicarboxylic acid. The surfactant gelling agents can be adsorbed onto particulate supports to facilitate delivery of the gelling agent. The additives may be incorporated in the viscoelastic fluid to tailor its use in hydraulic fluids, drilling muds, fracture fluids, and in applications such as permeability modification, gravel packing, cementing, and the like.Type: GrantFiled: December 19, 1997Date of Patent: May 29, 2001Assignee: Akzo Nobel NVInventors: Robert F. Farmer, Andress K. Doyle, Glenda Del Carmen Vale, James F. Gadberry, Michael D. Hoey, Randy E. Dobson
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Patent number: 6118012Abstract: A novel compound bearing urethane linkage of formula as shown herebelow, which is an adduct of ricinoleic ester and isocyanate, useful as a plasticizer for polyvinylchloride (PVC) and a process for the preparing the compound bearing urethane linkage by reacting fatty acid esters bearing hydroxyl groups with an organic isocyanate in die presence of a catalyst at a temperature in the range of 30.degree.-100.degree. C.Type: GrantFiled: April 1, 1999Date of Patent: September 12, 2000Assignee: Council of Scientific & Industrial ResearchInventors: Srinivasan Subbagiri Ramaswamy Iyengar, Raut Kundalik Ganpat, Saxena Prabhat Kumar, Sivaram Swaminathan
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Patent number: 5925775Abstract: Amidopropyl-N-alkyl-polyhydroxyalkylamines of the following formula (1) ##STR1## in which Z is a linear polyhydroxyhydrocarbon radical having at least 2 free or oxyalkylated hydroxyl groups, R.sup.1 is a C.sub.1 to C.sub.7 -alkyl radical or C.sub.2 to C.sub.4 -hydroxyalkyl radical and COR is an aliphatic acyl radical having 6 to 22 carbon atoms, and salts thereof from an inorganic or organic acid are described. They are prepared by a) reaction of a compound of the formula (2) ##STR2## with acrylonitrile to give the compound of the formula (3) ##STR3## b) hydrogenation of the product obtained in step a) to give the compound of the formula (4) ##STR4## and c) monoacylation of the product obtained in step b) in the melt to give the compound of the formula (1) mentioned. The compounds according to the invention are readily soluble in water and water/alcohol mixtures and are advantageous co-surfactants for use in detergents and cleaning compositions and in cosmetic preparations for cleansing the hair and skin.Type: GrantFiled: August 2, 1996Date of Patent: July 20, 1999Assignee: Clariant GmbHInventors: Gunter Prossel, Reinhard Vybiral, Werner Skrypzak, Hans Jurgen Scholz
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Patent number: 5919959Abstract: The present invention deals with the composition of matter and the utilization of certain novel guerbet based amine oxide compounds. These materials are useful in personal care applications.Type: GrantFiled: June 18, 1998Date of Patent: July 6, 1999Assignee: Lambent Tech IncInventor: Anthony J. O'Lenick, Jr.
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Patent number: 5907049Abstract: The present invention deals with the composition of matter and the utilization of certain amine oxides of meadowfoam amido propyl dimethyl amine. These materials are useful in personal care applications.Type: GrantFiled: May 11, 1998Date of Patent: May 25, 1999Assignee: Fan Tech LTDInventor: Anthony J. O'Lenick, Jr.
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Patent number: 5861520Abstract: The present invention provides a compound which is a glycolipid analog having a novel structure represented by the formula (1): ##STR1## wherein Z represents an imino group, an oxygen atom or a sulfur atom; m is an integer of from 3 to 12; and n is an integer of from 4 to 22; and shows a potent activity of inhibiting glycosidase and has potential physiological activities, for example, antiviral activity. The invention also provides a glycosidase inhibitor which comprises said glycolipid analog as an active ingredient.Type: GrantFiled: May 31, 1995Date of Patent: January 19, 1999Assignee: Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation)Inventors: Seiichiro Ogawa, Hidetoshi Tsunoda, Jinichi Inokuchi
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Patent number: 5654452Abstract: Aromatic acid-derived lipophilic polyhalogenated compounds are provided for use as contrast agents in diagnostic imaging or as therapeutic agents. These compounds are particularly useful when incorporated into an oil-in-water emulsion for tissue-specific delivery to the liver. For hepatocyte-selective delivery, the emulsion is chylomicron remnant-like by being in a size range of 50 to 200 nm and having a composition simulating naturally-occuring chylomicron remnants.Type: GrantFiled: June 7, 1995Date of Patent: August 5, 1997Assignee: Molecular Biosystems, Inc.Inventors: Rolf Lohrmann, Dung K. Hong
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Patent number: 5646143Abstract: .delta.-Amino-.gamma.-hydroxy-.omega.Type: GrantFiled: July 25, 1996Date of Patent: July 8, 1997Assignee: Ciba-Geigy CorporationInventors: Richard Goschke, Jurgen Klaus Maibaum, Walter Schilling, Stefan Stutz, Pascal Rigollier, Yasuchika Yamaguchi, Nissim Claude Cohen, Peter Herold
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Patent number: 5627182Abstract: .delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients.Type: GrantFiled: July 25, 1996Date of Patent: May 6, 1997Assignee: Ciba Geigy CorporationInventors: Richard G oschke, J urgen K. Maibaum, Walter Schilling, Stefan Stutz, Pascal Rigollier, Yasuchika Yamaguchi, Nissim C. Cohen, Peter Herold
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Patent number: 5614649Abstract: Disclosed herein are inhibitors of the multicatalytic protease enzyme which are represented by the general formula: ##STR1## Constituent members and preferred constituent members are disclosed herein. Methodologies for making and using the disclosed compounds are also set forth herein.Type: GrantFiled: November 3, 1995Date of Patent: March 25, 1997Assignee: Cephalon, Inc.Inventors: Mohamed Iqbal, James L. Diebold, Robert Siman, Sankar Chatterjee, James C. Kauer
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Patent number: 5587513Abstract: The present invention relates to novel polyether-substituted compounds of imides and their use as surface-active agents.Type: GrantFiled: January 20, 1995Date of Patent: December 24, 1996Inventors: Klaus Pohmer, Rainer Weber, Cornelia D orzbach-Lange, Reinhard Haida, Hans-Heinrich Moretto
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Patent number: 5547990Abstract: It has been found that certain combinations of substituted imidazoline-based amphoterics and quaternary ammonium compounds show markedly reduced irritation profile in addition to providing excellent cleaning detergency. Moreover, it has further been found that certain substituted imidazoline amphoteric surfactants in combination with didecyl dimethyl ammonium chloride (DIDAC) show unexpected synergistic irritation reduction compared to that observed when the quaternary is an ADBAC type. This allows the formulation of disinfectants and sanitizers with the favored antimicrobial agent while at the same time affording the optimum reduction in irritation potential.Type: GrantFiled: May 20, 1994Date of Patent: August 20, 1996Assignee: Lonza, Inc.Inventors: Larry Hall, Michael Y. Chiang, Judith M. Meyer
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Patent number: 5470878Abstract: Therapeutic compounds have the formula:(X)j-(non-cyclic core moiety),j being an integer from one to three, the core moiety is non-cyclic and X is a racemic mixture, R or S enantiomer, solvate, hydrate, or salt of: ##STR1## *C is a chiral carbon atom, n is an integer from one to four (preferably from one to three), one or more carbon atoms of (CH.sub.2).sub.n may be substituted by a keto or hydroxy group, and m is an integer from one to fourteen. Independently, R.sub.1 and R.sub.2 may be a hydrogen, a straight or branched chain alkane or alkene of up to twelve carbon atoms in length, or --(CH.sub.2).sub.w R.sub.5, w being an integer from two to fourteen and R.sub.5 being a mono-, di- or tri-substituted or unsubstituted aryl group, substituents on R.sub.5 being hydroxy, chloro, fluoro, bromo, or C.sub.1-6 alkoxy. Or jointly, R.sub.1 and R.sub.2 form a substituted or unsubstituted, saturated or unsaturated heterocyclic group having from four to eight carbon atoms, N being a hetero atom. R.sub.Type: GrantFiled: December 8, 1993Date of Patent: November 28, 1995Assignee: Cell Therapeutics, Inc.Inventors: John Michnick, Gail E. Underiner, J. Peter Klein, Glenn C. Rice
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Patent number: 5318727Abstract: A cationic compound is useful for a cleaning agent such as shampooing and defined by the formula (I): ##STR1## in which R1 is straight or branched and an alkyl having 7 to 15 carbon atoms or an alkenyl having 7 to 15 carbon atoms; R2, R3 and R4, independently of one another, are an alkyl having 1 to 3 carbon atoms; G is hydrogen atom, an alkyl having 1 to 3 carbon atoms or a hydroxyalkyl having 1 to 3 carbon atoms, E is hydrogen atom, an alkyl having 1 to 3 carbon atoms, a hydroxyalkyl having 1 to 3 carbon atoms or an ammonium group having the formula (II): ##STR2## Y being hydrogen atom or hydroxy, A being hydroxy, a halogen atom or an alkylsulfate having 1 to 4 carbon atoms, m being 2 or 3, n being zero or an integer of 1 to 5, provided that (1) when G is an alkyl or a hydroxyalkyl, E is neither an alkyl nor a hydroxyalkyl, (2) when n is 1, Y is hydrogen atom or hydroxy and when n is zero, 2, 3, 4 or 5, Y is hydrogen atom and (3) G and E cannot both be hydrogen.Type: GrantFiled: August 14, 1991Date of Patent: June 7, 1994Assignee: Kao CorporationInventors: Yasuki Ohtawa, Makoto Kubo, Hiroyuki Imoto, Takashi Matsuo, Kazuyuki Yahagi, Koshiro Sotoya
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Patent number: RE41585Abstract: A method for controlling the rheology of aqueous systems, particularly for those intended for underground use, includes injecting an aqueous fluid containing a surfactant gelling agent into the system. The surfactant gelling agents are, for example, fatty aliphatic amidoamine oxides, salts of an alkoxylated monoamine with an aromatic dicarboxylic acid, and salts of an alkyldiamine with an aromatic dicarboxylic acid. The surfactant gelling agents can be absorbed onto particulate supports to facilitate delivery of the gelling agent. The additives may be incorporated in the viscoelastic fluid to tailor its use in hydraulic fluids, drilling muds, fracture fluids, and in applications such as permeability modification, gravel packing, cementing, and the like.Type: GrantFiled: May 30, 2002Date of Patent: August 24, 2010Inventors: Robert F. Farmer, Andress K. Doyle, Glenda Del Carmen Vale, James F. Gadberry, Michael D. Hoey, Randy E. Dobson