Abstract: Disclosed are formulation and optimization protocols for delivery of therapeutically effective amounts of biologically active agents to liver, tumors, and/or other cells or tissues. Also provided are compositions and uses for cationic lipid compounds of formula (I). The invention also relates to compositions and uses for stealth lipids of formula (XI). Also provided are processes for making such compounds, compositions, and formulations, plus methods and uses of such compounds, compositions, and formulations to deliver biologically active agents to cells and/or tissues.

Abstract: A process is provided for preparing C8-C22 acyl glycinate acid or salt thereof via reacting and heating a mixture of glycine or salt thereof with a C1-C3 alkyl ester of a C8-C22 fatty acid in a medium of glycerol or propylene glycol. The reaction proceeds well where the mixture is formulated to have a pKa ranging from 9.5 to 13.

Abstract: The present invention is directed to transdermal compositions and the uses thereof. These compositions include at least one of the following components: a C1-C6 dialkyl, C12-C30 dialkyl quaternary ammonium salt, a C12-C30 fatty acid, a nitrogenous organic base, C12-30 fatty alcohol, monoglyceride or the reaction products thereof.

Abstract: The present invention is directed to transdermal compositions and the uses thereof. These compositions include at least one of the following components: a C1-C6 dialkyl, C12-C30 dialkyl quaternary ammonium salt, a C12-C30 fatty acid, a nitrogenous organic base, C12-30 fatty alcohol, monoglyceride or the reaction products thereof.

Abstract: The invention relates to fatty acid amides; compositions comprising an effective amount of a fatty acid amide; and methods for treating or preventing cancer, a metabolic disease or a neurodegenerative disease comprising the administration of an effective amount of a fatty acid amide.

Abstract: A liquid for discharge includes: a biospecimen; and at least one kind of compounds represented by the formula (1). In the formula (1), m?8, and 6?n?20.

Abstract: A process is described for preparing alkylene oxide-adducted hydrocarbyl amides having less than 2 wt % of amine by-products by a) reacting a C4-C30 fatty acid or fatty acid lower alkyl ester with a mono- or di-hydroxy hydrocarbyl amine to form a hydrocarbyl amide; b) reacting the hydrocarbyl amide with alkylene oxide; and c) extracting the product of b) with water, acidic water, or water-containing inorganic salts or a combination thereof at a temperature from about 5° C. to 95° C. to yield an alkylene oxide-adducted hydrocarbyl amide having less than 2 wt % of amine by-products.

Abstract: Provided for are rinse aids that exhibit improved drying properties during automatic dish washing and thus allow cleaning methods at lower temperatures than customer reference agents. The rinse aids comprise a) at least one surfactant according to the general formula (I), where R1 is a saturated or unsaturated, branched or linear alkyl or alkenyl radical having 6 to 22 carbon atoms, R2 is hydrogen or an alkyl group having 1 to 6 carbon atoms or a group R3, and R3 is a group A-(O—CH2CHR4—)m—OR5 and R4 and R5 independently from each other are a hydrogen atom or an alkyl group having 1 to 4 carbon atoms and A is a (CH2)n— group or a hydroxyl alkyl group having 2 to 6 carbon atoms and n is an integer from 1 to 6 and m is an integer or a fractional number from 1 to 10 and furthermore b) at least one hydrotrope, c) at least one organic hydroxycarboxylic acid and d) water.

Abstract: A liquid for discharge includes: a biospecimen; and at least one kind of compounds represented by the formula (1). In the formula (1), m?8, and 6?n?20.

Abstract: Disclosed herein are compounds having a formula of R1—CONH—R6—CONH—R3, R1—NHCO—R6—CONH—R3, R1—CONH—R6—NHCO—R3 or R1—NHCO—R6—NHCO—R3, wherein R6 is a cyclic group having from 5 to 8 carbon atoms, wherein R1 and R3 are the same or different and comprise an alkyl group having from about 3 carbon atoms to about 200 carbon atoms, and wherein one or both of R1 and R3 include at least one hydroxyl group substituent, and ink compositions including the compounds as an ink vehicle.

Abstract: Novel alkanolamides prepared by the reaction of an alkanolamine and shea butter, preferably mild-processed shea butter (MPSB). Materials of the present invention are useful as cosmetic and personal care ingredients; they thicken shampoos and body washes, stabilize foam, and deliver to the hair and skin highly desirable unsaponifiables present in shea butter, including natural antioxidants.

Abstract: The use of amidoamines to treat or prevent infections attributable to Acanthamoeba and fungi is described. The amidoamines are highly effective against both Acanthamoeba and fungi, and are less toxic to delicate tissues that may become infected with these types of microorganisms (e.g., the cornea).

Abstract: The invention relates to a heat-sensitive compound having the property of being soluble in water below a critical temperature Tc and insoluble in water above this temperature Tc, this property being thermally reversible, characterized in that it comprises a first amphiphilic and thermally reversible part corresponding to one of the following formulae (I) and (II): in which i is an integer ranging from 1 to 20 and j is an integer ranging from 3 to 30. This compound can be used to extract a chemical entity, such as uranium.

Abstract: Novel ceramide compounds, compositions containing them and the use of these compounds, in particular for strengthening the lipid barrier of the epidermis.

Abstract: The present invention relates to a polyethoxylated retinamide derivative represented by formula (I), which is useful as an agent for inhibiting skin aging; in R represents hydrogen or C1-6 lower alkyl and n denotes the number of 2 to 100, and the process for preparing the compound of formula (I) as an effective component.

Abstract: Monoamide-containing polyether alcohol compounds of the formula: wherein R1, R2 and R3 are each independently selected from hydrogen, hydrocarbyl of 1 to 100 carbon atoms, substituted hydrocarbyl of 1 to 100 carbon atoms and polyoxyalkylene alcohol of 2 to 200 carbon atoms or R2 and R3 taken together form a heterocyclic group of 2 to 100 carbon atoms or a substituted heterocyclic group of 2 to 100 carbon atoms with the proviso that at least one of R1, R2 or R3 must be polyoxyalkylene alcohol have been found to decrease intake valve deposits, control octane requirement increases and reduce octane requirement when used as gasoline additives.

Abstract: Disclosed herein is a ceramide-like compound having properties of the natural ceramides, and a method for producing the same, and a cosmetic composition containing the same as a active ingredient.

Abstract: This invention relates to amide derivatives represented by the following formula (1), amide derivative synthesis intermediates represented by the following formula (2), (3) or (4), and external skin care preparations, cosmetic hair care formulations and bath medicines containing the amide derivatives (1): ##STR1## wherein R.sup.1 and R.sup.1a are, for example, tetradecyl or hexadecyl, R.sup.2 is, for example, tridecyl or pentadecyl, R.sup.3 is, for example, ethylene or trimethylene, R.sup.3a is, for example, trimethylene, and R.sup.4, R.sup.4a and R.sup.4b are, for example, methoxy or ethoxy. When added to external skin care preparations, bath medicines and cosmetic hair care formulations, the amide derivatives (1) exhibit advantageous effects such as skin-roughness preventing/curing effects and hair touch-feeling improving effects.

Abstract: Multiple amide polyether alcohol compounds of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are each independently selected from the group consisting of hydrocarbyl of 2 to 100 carbon atoms and substituted hydrocarbyl of 2 to 100 carbon atoms; R.sub.3 and R.sub.4 are each independently selected from the group consisting of hydrocarbyl of 1 to 100 carbon atoms, substituted hydrocarbyl of 1 to 100 carbon atoms and polyoxyalkylene alcohol of 2 to 200 carbon atoms; R.sub.5 is selected from the group consisting of alkylene of 2 to 20 carbon atoms and alkylene of 2 to 20 carbon atoms having at least one methylene group replaced by at least one oxygen atom or at least one acylated nitrogen atom; x and y are each from 1 to 50 and the weight average molecular weight of the additive compound is greater than about 600 when used as gasoline additives are found to decrease intake valve deposits.

Abstract: A compound represented by the formula (I) is disclosed. The compound of the formula (I) is useful as a fine particle drug carrier. When used as the fine particle drug carrier, the compound efficiently avoids a reticuloendothelial system and has a long circulation time in blood.

Abstract: The present invention deals with the certain novel meadowfoam derived sulfosuccinates. These materials are useful as cosmetic ingredients as additives to shampoo systems where outstanding liquidity, resistance to oxidation, and minimal odor variation are required.

Abstract: The use of endgroup-capped fatty amide alkoxylates IR.sup.1 --CO--NH--(CH.sub.2).sub.n --O--(AO).sub.x --R.sup.2(I)whereR.sup.1 is C.sub.5 -C.sub.21 -alkyl or -alkenyl,R.sup.2 is C.sub.1 -C.sub.4 -alkyl,A is C.sub.2 -C.sub.4 -alkylene,n is 2 or 3, andx has a value from 1 to 6,as nonionic surfactants or emulsifiers in detergents, cleaners or body care compositions, as surface-active substances for industrial applications in electroplating, in the photographic industry, in petroleum production, in the pharmaceutical industry, in plant feeding and in crop protection formulations, and as surface-active substances in the production of emulsions and pigment and plastic dispersions.

Abstract: A process for preparing a surfactant composition comprising reacting an N-alkylpolyhydroxyamine and an alkoxylated triglyceride of a fatty acid to produce a mixture of a polyhydroxy-fatty amide, an alkoxylated monoglyceride of a fatty acid, and an alkoxylated diglyceride of a fatty acid, the resulting mixture providing a water soluble surfactant composition.

Abstract: The present invention deals with the certain novel alkanolamides which are prepared by the reaction of an alkanolamie and meadowfoam fatty, methyl ester or triglyceride. These materials are useful as cosmetic ingredients as additives to shampoo systems where outstanding liquidity, resistance to oxidation, and minimal odor variation are required.

Abstract: The efficacy of an agricultural chemical can be enhanced by using a specific fatty acid alkanolamide or a fatty acid ester or carboxymethylated derivative thereof represented by the following formula (I) together with the agricultural chemical: ##STR1## wherein R.sup.1 represents a linear or branched alkyl or alkenyl group having 5 to 29 carbon atoms; each R.sup.2 represents a hydrogen atom or a methyl group; each R.sup.3 represents a hydrogen atom or a methyl group; R.sup.4 and R.sup.5 may be the same or different from each other and each independently represents a hydrogen atom, a group represented by the formula: ##STR2## wherein R.sup.6 represents a linear or branched alkyl or alkenyl group having 1 to 29 carbon atoms, or a group represented by the formula: --CH.sub.2 COOX, wherein X represents a hydrogen atom, a sodium atom, a potassium atom, an ammonium group or an organic ammonium group.

Abstract: Novel amide derivatives have the following structure (1): ##STR1## where Y is hydrogen or an unsaturated fatty acid residue,A is an hydroxyalkyl group,B is a sugar or phosphate residue, and(C.sub.a H.sub.b) is a hydrocarbon residue with from 7 to 49 carbon atoms.The amide derivative can be employed in compositions, together with a suitable carrier, for topical application, particularly to improve damaged human skin or hair.

Abstract: Insecticidal and acaricidal compounds of FormulaAR(CH.sub.2).sub.x O(CH.sub.2).sub.m A(CH.sub.2).sub.n (CE.sup.1 =CE.sup.2).sub.a (CE.sup.3 =CE.sup.4)CONR.sup.1 R.sup.2 (I)whereinAr is phenyl or naphthyl, in either case optionally substituted by one or more of optionally substituted C.sub.1-6 alkyl, optionally substituted C.sub.1-6 -alkylthio or C.sub.1-6 alkylthiooxy, halogen or optionally substituted C.sub.1-6 alkoxy,x=0 or 1m=1 to 7n=1 to 7A=CH.sub.2 or oxygena=0 or 1R.sup.1 and R.sup.2 are independently selected from hydrogen, C.sub.1-6 alkyl and C.sub.3-6 cycloalkyl (either of which may be substituted by one or more of halo, C.sub.1-6 alkyl, C.sub.2-6 alkenyl, CF.sub.2-6 alkoxy, C.sub.2-6 alkynyl, dioxalanyl and C.sub.3-6 cycloalkyl)E.sup.1, E.sup.2, E.sup.3 and E.sup.4 are independently selected from hydrogen, C.sub.1-4 alkyl, optionally substituted by halo, and nitrile, provided that at least one of E.sup.1, E.sup.2, E.sup.3 and E.sup.

Abstract: Alkoxylates of active hydrogen compounds having a peaked molecular weight distribution are prepared by reacting the active hydrogen compound with an alkylene oxide of from 2 to 4 carbon atoms using iron oxides as alkoxylation catalysts.

Abstract: The invention relates to mixtures of amidated fatty acids or derivatives thereof of the general formula ##STR1## wherein R' is absent or an alkyl group with 2-4 C-atoms, the average value of n is 0,5 to 3 and R represents a fatty acid radical with 14-24 C-atoms obtained from oils produced from the plant species `Brassica` with an eruca acid content lower than 5%.These products are good thickeners for surfactants and/or detergents. No nitrose compounds of (di)alkanolamines, which could present a health hazard, are formed in the thickeners according to the invention.