Having -c(=x)-, Wherein X Is Chalcogen, Bonded Directly To The Nitrogen Patents (Class 556/411)
  • Patent number: 8895137
    Abstract: The present invention relates to a multilayer system comprising a base layer consisting of a thermoplastic, a primer layer, and a scratch resistant layer consisting of a scratch resistant top coat, the multilayer system being characterized in that the primer layer contains a certain UV absorber and a certain amount of acid, preferably acetic acid, is added to the scratch resistant top coat.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: November 25, 2014
    Assignee: Bayer MaterialScience AG
    Inventors: Birgit Meyer Zu Berstenhorst, Peter Capellen
  • Patent number: 8778224
    Abstract: The present invention provides a fluorescent dye-silane hybrid resin manufactured by polycondensing an alkoxysilane bonded with a fluorescent dye with an organo-silane. More particularly, the present invention provides a fluorescent dye-siloxane hybrid resin that is manufactured by reacting a fluorescent dye having one or more functional groups with an alkoxysilane having an organic functional group to form an alkoxysilane bonded with the fluorescent dye and then polycondensing the alkoxysilane bonded with a fluorescent dye with an organo-silanediol and an organo-alkoxysilane having a thermocurable or ultraviolet-curable functional group without water. The fluorescent dye-silane hybrid resin has excellent thermostability, photostability, fluorescence characteristics, and processibility.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: July 15, 2014
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: Byeong-Soo Bae, Seung-Yeon Kwak
  • Publication number: 20140171542
    Abstract: The invention provides an amphiphilic siloxane-containing vinylic monomer which comprises one sole ethylenically unsaturated group and a siloxane-containing group covalently linked to the ethylenically-unsaturated group through a hydrophilic linker. The present invention is also related to a polymer, an actinically-crosslinkable silicone-containing prepolymer, a silicone hydrogel polymeric material, or a silicone hydrogel contact lens, which comprises monomeric units derived from an amphiphilic siloxane-containing vinylic monomer of the invention. In addition, the invention provides a method for making silicone hydrogel contact lenses using a water-based lens-forming formulation comprising an amphiphilic siloxane-containing vinylic monomer of the invention and/or an actinically-crosslinkable silicone-containing prepolymer of the invention.
    Type: Application
    Filed: December 13, 2013
    Publication date: June 19, 2014
    Applicant: Novartis AG
    Inventor: Frank Chang
  • Publication number: 20140024805
    Abstract: The present invention relates to a process for producing N-alkyl-N-trialkylsilylamides from trialkylsilylhalides and N-alkylamides in the presence of a base and in the absence of a solvent.
    Type: Application
    Filed: April 2, 2012
    Publication date: January 23, 2014
    Applicant: SOLVAY S.A.
    Inventors: Roland Callens, Andre Collin
  • Patent number: 8450512
    Abstract: Disclosed herein are methods for a simple process to make 3-aminoorgano functional silanes and siloxanes, free from isomers, by the use of commonly available materials. One embodiment of such a method comprises reacting aminoorgano functional silanes with hexamethyldisilazane in the presence of an acidic catalyst to produce a cyclic gamma-functional aminoorganic silane and beta isomers; separating the cyclic gamma-functional aminoorganic silane and the beta isomers; and converting the separated cyclic gamma-functional aminoorganic silane to pure gamma-aminoalkylsilane or pure aminoorganic siloxane. Also disclosed herein are cyclic derivatives of gamma-functional aminoorganic silanes.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: May 28, 2013
    Assignee: Genesee Polymers Corporation
    Inventors: Charles Piskoti, Charles R. Piskoti
  • Patent number: 8304571
    Abstract: The present invention relates to a perfluoropolyether-modified polysiloxane represented by general formula (1): wherein X is a divalent group represented by formula —CH2—, —CH2O—, —CH2OCH2— or —Y—NR—CO—, R1, R2, and R3 are, independently of each other, an alkyl group having 1 to 10 carbon atoms or an aryl group; X? is a divalent group represented by formula —CH2—, —OCH2—, —CH2OCH2— or —CO—NR—Y?—, a is, independently of each other, 0 or 1; z and z? are, independently of each other, an integer of 5 to 100; and Rf is a divalent group represented by the following general formula (2): —CtF2t[OCF2CF(CF3)]m—OCF2(CF2)rCF2O[CF(CF3)CF2O]nCtF2t—??(2) or by the following general formula (3): —Ct?F2t?(OCF2CF2)u(OCF2)vOCt?F2t?—??(3).
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: November 6, 2012
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Hiromasa Yamaguchi, Noriyuki Koike
  • Patent number: 8247591
    Abstract: A nanoparticle includes a chain oligomer section having a hydrophilic group and fluoroalkyl groups respectively at its opposite terminals, a three-dimensional silica network section, and an organic chain having fluorine or silicon, and is represented by the following formula (2): where R? is independent H or independent alkyl group; X is the hydrophilic group and is selected from the group consisting of an OH group, an NCO group, an NH2 group, an NHR group (where R is alkyl group) and a COY group (where Y is a hydrophilic group); RF is the fluoroalkyl group having a carbon number of 2 to 10 and a molecular weight of 119 to 1000; 3D-SN is the three-dimensional silica network section; B is selected from the group consisting of an O, O?C—O, NH—C?O and NR—C?O (where R is alkyl group); E is O, O?C—O, NH—C?O or NR—C?O (where R is alkyl group); L is (CH2O)l—[Si(CH3)2O]k—(CH2O)l-?, (CF2)j-? or (CF2O)h-? where ? is COY group (where Y is hydrophilic group), NCO group, NH2 group, NHR group (R is alkyl group), R grou
    Type: Grant
    Filed: October 22, 2010
    Date of Patent: August 21, 2012
    Assignee: Nissan Motor Co., Ltd.
    Inventors: Hideaki Yaegashi, Shoko Kano, Masahiko Yamanaka, Kentarou Watanabe, Hiroshi Yokoyama, Hideo Sawada
  • Publication number: 20120045515
    Abstract: The present invention provides a hollow silica micro- or nanoparticle with a polymer immobilized thereon. The polymer is covalently linked to the silica particle via urethane groups. Provided is also a method of covalently coupling a polymer to a silica surface. The method comprises contacting a silica surface that carries amino functional groups with a polymer with a carbonate group of the general Formula (2). R2 in Formula (2) is the polymer and R3 is one of an aliphatic, an alicyclic an aromatic and an arylaliphatic group or a silyl group with a main chain of about 1 to about 20 carbon atoms and 0 to about 6 heteroatoms selected from the group consisting of N, O, S, Se and Si. The method further comprises allowing the carbonate group of the polymer and an amino functional group on the silica surface to undergo a coupling reaction, thereby covalently coupling the polymer to the silica surface.
    Type: Application
    Filed: January 25, 2010
    Publication date: February 23, 2012
    Inventors: Ye Liu, Decheng Wu
  • Publication number: 20120045396
    Abstract: Biodegradation kinetics of biodegradable porous objects, such as porous silicon objects, can be controlled by a molecular weight of polymer chains, such as polyethylene glycol chains, disposed on an outer surface of the object. Provided are biodegradable porous objects, which have their biodegradation kinetics controlled by a molecular weight of the disposed polymer chains. Also provided are methods of making such biodegradable porous objects as well as methods of using such biodegradable porous objects for delivery of active agents, such as therapeutic agents and/or imaging agents.
    Type: Application
    Filed: January 15, 2009
    Publication date: February 23, 2012
    Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Biana Godin-Vilentchouk, Mauro Ferrari
  • Publication number: 20110123413
    Abstract: The present invention generally relates to coating materials, including photoactive coating materials. In some aspects of the invention, a sol-gel is provided that can be formed as a coating on a microfluidic channel. One or more portions of the sol-gel can be reacted to alter its hydrophobicity, in some cases. For instance, in one set of embodiments, a portion of the sol-gel may be exposed to light, such as ultraviolet light, which can be used to induce a chemical reaction in the sol-gel that alters its hydrophobicity. In one set of embodiments, the sol-gel can include a photoinitiator, that upon exposure to light, produces radicals. Optionally, the photoinitiator may be conjugated to a silane or other material within the sol-gel. The radicals so produced may be used to cause a polymerization reaction to occur on the surface of the sol-gel, thus altering the hydrophobicity of the surface. In some cases, various portions may be reacted or left unreacted, e.g.
    Type: Application
    Filed: February 11, 2009
    Publication date: May 26, 2011
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Adam R. Abate, Amber T. Krummel, David A. Weitz
  • Publication number: 20110087040
    Abstract: A bromine/nitro moiety linked into the backbone of an ester or other compound over a wide range of occurrence rates provides antimicrobial, bio-resistant and fungal resistant properties for metal working fluids (MWF)s and other coatings. The moiety can be have the bromo and nitro groups linked to the same or different carbon atoms. The present invention also relates to urethanes, urea, amides, imides, carbonates, ethers, siloxanes, and many other types of linkages essential to MWF bases.
    Type: Application
    Filed: December 10, 2010
    Publication date: April 14, 2011
    Inventor: Thomas Daly
  • Publication number: 20110053375
    Abstract: A method for processing an amorphous carbon film which has been formed on a substrate and wet-cleaned after being dry-etched includes preparing the substrate having the wet-cleaned amorphous carbon film and modifying a surface of the amorphous carbon film, before forming an upper layer on the wet-cleaned amorphous carbon film.
    Type: Application
    Filed: January 9, 2009
    Publication date: March 3, 2011
    Applicant: TOKYO ELECTRON LIMITED
    Inventors: Hiraku Ishikawa, Takaaki Matsuoka
  • Patent number: 7803958
    Abstract: A crosslinker (i.e., a curing agent) for polymerizing a film-forming material. The crosslinker is an organic compound including at least two functional groups reactive with a film-forming material and at least one pendent group comprising a —Si(OR)3 group, wherein each R is independently an alkyl group including from 1 to about 12 carbon atoms or an aryl group including substituted and unsubstituted phenyl and benzyl groups. Functional groups reactive with a film-forming materials include isocyanate, blocked isocyanate, uretdione, epoxide, hydroxyl, carboxyl, ester, ether, carbamate, aminoalkanol, aminoalkylether, amide, or amine groups. Embodiments include derivatives of the various crosslinkers as disclosed elsewhere herein, where the crosslinker has at least two functional groups reactive with a film-forming material and at least one pendent group comprising a —Si(OR)3 group.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: September 28, 2010
    Assignee: BASF Coatings GmbH
    Inventors: Sergio Gonzalez, Timothy S. December
  • Patent number: 7652163
    Abstract: Cyclic silazanes containing an oxamido ester group and methods of making these compounds are described. The compounds can be used, for example, to make oxamido ester-terminated siloxanes, which can be precursors for the preparation of various polymeric materials such as, for example, polydiorganosiloxane polyoxamides.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: January 26, 2010
    Assignee: 3M Innovative Properties Company
    Inventors: Charles M. Leir, Karl E. Benson, Richard G. Hansen
  • Patent number: 7592474
    Abstract: Silanes of the formula: [(ZmRnSi—R1o—)pR2q—Y—C(X)—Y—]rG[—Y—(X)C—Y—R3]s??(I), in which m+n=3; m=1, 2 or 3; n=0, 1 or 2; o=0 or 1, and q=1 if o=0; p=1, 2, 3 or 4; q=0 or 1, and p=1 if q=0; r, s=1, 2 or 3; and Z is a hydrolyzable atom or group; R is a nonhydrolyzable group without an epoxide group; R1 is a divalent group; R2 is a (p+1)-valent group; R3 is a nonhydrolyzable, epoxy-containing group; X is an oxygen atom and/or sulfur atom; G is an (r+s)-valent cyclic group; Y is an oxygen atom, sulfur atom or imino group >NR4 where R4=hydrogen atom, group R, group (ZmRnSi—R1o—)pR2q—, group R3—, group (ZmRnSi—R1o—)pR2q—NH—C(X)— or group R3—NH—C(X)—; processes for their preparation, and their use.
    Type: Grant
    Filed: April 23, 2004
    Date of Patent: September 22, 2009
    Assignee: BASF Coatings AG
    Inventors: Andreas Poppe, Elke Westhoff, Winfried Stübbe
  • Patent number: 7507849
    Abstract: Cyclic silazanes containing an oxamido ester group and methods of making these compounds are described. The compounds can be used, for example, to make oxamido ester-terminated siloxanes, which can be precursors for the preparation of various polymeric materials such as, for example, polydiorganosiloxane polyoxamides.
    Type: Grant
    Filed: June 22, 2007
    Date of Patent: March 24, 2009
    Assignee: 3M Innovative Properties Company
    Inventors: Charles M. Leir, Karl E. Benson, Richard G. Hansen
  • Patent number: 7087776
    Abstract: Compounds of formula (I, II, or III), wherein X is OH; Y is OH, H, lower alkyl of one to six carbons or heteroatoms or F; Z and Z? are independently H, lower alkyl or Q3Si where Q is lower alkyl or aryl; n is 3–50; n? is 2–50; A and B are independently a) alkyl of one to ten carbons or heteroatoms, b) aryl of four to ten carbons or heteroatoms, c) cyclic of three to ten carbons or heteroatoms, or moieties of the formulas (d, e, or f); R1–R11 groups are each independently hydrogen, alkyl of one to ten carbons or heteroatoms, aryl of 4 to 14 carbons or heteroatoms, arylalkyl of five to twenty carbons or heteroatoms; unsubstituted carbonyl or substituted carbonyl. Heteroatoms are nitrogen, oxygen, silicon or sulfur. At least one of A or B, or both A and B are d), e), or f). The compounds of formula (I) inhibit protease enzymes and can be used as pharmaceuticals.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: August 8, 2006
    Assignee: Research Foundation of State University of New York
    Inventors: Scott McN. Sieburth, Alfred M. Mutahi, Chien-An Chen
  • Patent number: 6998499
    Abstract: Iminoorganosilanes may be prepared by reacting aminoorganosilanes with organoimines by an amine exchange reaction. The resultant iminoorganosilanes can then be catalytically reduced to produce secondary and tertiary amino silanes. Imidoorganosilanes can be prepared by a similar amine reaction between aminoorganosilanes and organoimides. The imidoorganosilanes can also be reacted to produce tertiary amines. Water-sensitive silane reactants may be employed to yield water-sensitive imino, imido, or amino silane products.
    Type: Grant
    Filed: June 10, 2003
    Date of Patent: February 14, 2006
    Assignee: General Electric Company
    Inventors: Steven C. Gedon, Andrea Trotto
  • Patent number: 6960678
    Abstract: Compounds of formula (I, II or III), wherein X is OH; Y is OH, H, lower alkyl of one to six carbons or heteroatoms or F; Z and Z? are independently H, lower alkyl or Q3Si where Q is lower alkyl or aryl; n is 3-50; n? is 2-50; A and B are independently a) alkyl of one to ten carbons or heteroatoms, b) aryl of four to seven carbons or heteroatoms, c) cyclic of three to ten carbons or heteroatoms, or moieties of the formulas (d, e, or f); R1-R11 groups are each independently hydrogen, alkyl of one to ten carbons or heteroatoms, aryl of 4 to 14 carbons or heteroatoms, arylalkyl of five to twenty carbons or heteroatoms; unsubstituted carbonyl or substituted carbonyl. Heteroatoms are nitrogen, oxygen, silicon or sulfur. At least one of A or B, or both A and B are d), e), or f). The compounds of formula (I) inhibit protease enzymes and can be used as pharmaceuticals.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: November 1, 2005
    Assignee: The Research Foundation of State University of New York
    Inventors: Scott McN. Sieburth, Alfred M. Mutahi, Chien-An Chen
  • Patent number: 6881855
    Abstract: Silanes of the formula Ra1R4-a-xSiLx??(I) where each R is identical or different and is a monovalent, optionally substituted hydrocarbon radical which is free of aliphatic carbon—carbon multiple bonds and has from 1 to 18 carbon atoms per radical, R1 is an optionally substituted 2-norbornyl radical, L is a leaving group, a is 1, 2 or 3 and x is 1 or 2, with the proviso that the sum of a+x?4, are useful for protecting functional groups of organic compounds (2) which have at least one functional group having an active hydrogen atom, preferably as a hydroxyl group —OH, a thiol groups —SH, an amine group —NH— or —NH2, a carboxyl group —COOH, or an amide group —CONH— or —CONH2.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: April 19, 2005
    Assignee: Consortium fur Elektrochemische Industrie GmbH
    Inventors: Dieter Heldmann, Oliver Schaefer, Juergen Stohrer
  • Patent number: 6875243
    Abstract: Catalysts and processes for preparing polyisocyanates containing isocyanurate groups, and their use, wherein the catalysts are represented by the following formula (1): [Hl?Xm?Fn?]p·[R(4?q)Si(NR1R2)q]r??(I), wherein n=m+l with 1?m/n>0, and l?0, p>0 and r>0, and the ratio p/r is any value, q=1 or 2, and R, R1, R2 and X are as defined.
    Type: Grant
    Filed: November 27, 2002
    Date of Patent: April 5, 2005
    Assignee: Degussa AG
    Inventors: Michael Ewald, Manuela Windmueller, Waltraud Poersch, Stephan Kohlstruk
  • Patent number: 6803445
    Abstract: A moisture curable polyurethane composition comprising (A) a urethane prepolymer having two or more isocyanate groups in the molecule, (B) an inorganic filler as a storage stabilizer, (C) an N-silylamide compound represented by the formula (1), (D) an epoxy resin, and/or (E) a moisture latent curing agent, and a moisture curable epoxy resin composition comprising (D) an epoxy resin, (C) an N-silylamide compound, and (E) a moisture latent curing agent. (R1—CONH)4-n—Si—R2n  (1) wherein R1 is a hydrocarbon group having 5 to 21 carbon atoms optionally containing a heteroatom, provided that when n is 0, 1 or 2, R1s may be the same or different; and R2 is an alkyl or alkoxy group having 1 to 3 carbon atoms; and n is 0, 1, 2 or 3. The moisture curable compositions are excellent in storage stability and thixotropic properties, have high curing rates at the time of working, and can give rise to cured products having excellent mechanical properties such as tensile strength.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: October 12, 2004
    Assignee: The Yokohama Rubber Co., Ltd.
    Inventors: Kazunori Ishikawa, Hiroyuki Hosoda
  • Publication number: 20040138489
    Abstract: This invention relates to silicon precursor compositions for forming silicon-containing films by low temperature (e.g., <300° C.) chemical vapor deposition processes for fabrication of ULSI devices and device structures. Such silicon precursor compositions comprise at least one disilane derivative compound that is fully substituted with alkylamino and/or dialkylamino functional groups.
    Type: Application
    Filed: October 31, 2003
    Publication date: July 15, 2004
    Inventors: Ziyun Wang, Chongying Xu, Thomas H. Baum, Bryan Hendrix, Jeffrey F. Roeder
  • Publication number: 20030134977
    Abstract: Relatively high refractive index polymeric compositions and ophthalmic devices such as for example intraocular lenses and corneal inlays made therefrom are described herein. The preferred polymeric compositions are produced through the copolymerization of one or more aromatic-substituted polysiloxane prepolymers with one or more aromatic monomers, alkylated monomers or hydrophilic monomers.
    Type: Application
    Filed: November 2, 2001
    Publication date: July 17, 2003
    Inventors: Yu-Chin Lai, Edmond T. Quinn
  • Patent number: 6586612
    Abstract: Iminoorganosilanes may be prepared by reacting aminoorganosilanes with organoimines by an amine exchange reaction. The resultant iminoorganosilanes can then be catalytically reduced to produce secondary and tertiary amino silanes. Imidoorganosilanes can be prepared by a similar amine reaction between aminoorganosilanes and organoimides. The imidoorganosilanes can also be reacted to produce tertiary amines. Water-sensitive silane reactants may be employed to yield water-sensitive imino, imido, or amino silane products.
    Type: Grant
    Filed: November 16, 2001
    Date of Patent: July 1, 2003
    Assignee: Crompton Corporation
    Inventors: Steven C. Gedon, Andrea Trotto
  • Publication number: 20030032623
    Abstract: A purpose of the present invention is to provide TNF-&agr; production inhibitors being useful as therapeutic agents for autoimmune diseases such as rheumatoid arthritis.
    Type: Application
    Filed: June 21, 2002
    Publication date: February 13, 2003
    Inventors: Masakazu Ban, Hiroshi Suhara, Masato Horiuchi, Noriyoshi Yamamoto, Hiroshi Enomoto
  • Patent number: 6388117
    Abstract: Processes for preparing carbamatoorganosilanes from aminoorganosilanes, ureas and alcohols. These compounds are useful for surface modification of inorganic and organic materials, as adhesion promoters between inorganic materials and organic polymers, as crosslinking agents for the moisture-curing of polymers, for PU sealants, in the coating and adhesive sector, and for the production of biologically active products, such as insecticides and herbicides.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: May 14, 2002
    Assignee: Degussa AG
    Inventor: Klaus Pinske
  • Publication number: 20020032344
    Abstract: The invention concerns the synthesis of bis trialkylsilylamide which consists in: subjecting the amide to the action of a trialkylsilyl halide on an amide bearing a Rf group in the presence of a base whose halide, or halohydrate is insoluble in the medium and in the presence of a covalent and non-hydrophilic solvent. The invention is applicable to organic synthesis.
    Type: Application
    Filed: September 7, 1999
    Publication date: March 14, 2002
    Inventor: GERARD FORAT
  • Publication number: 20020016486
    Abstract: Processes for preparing carbamatoorganosilanes from aminoorganosilanes, ureas and alcohols. These compounds are useful for surface modification of inorganic and organic materials, as adhesion promoters between inorganic materials and organic polymers, as crosslinking agents for the moisture-curing of polymers, for PU sealants, in the coating and adhesive sector, and for the production of biologically active products, such as insecticides and herbicides.
    Type: Application
    Filed: December 14, 1999
    Publication date: February 7, 2002
    Inventor: KLAUS PINSKE
  • Publication number: 20020013459
    Abstract: The present invention relates to processes for the preparation of macrocyclic molecules containing anti-succinate residues which inhibit metalloproteinases such as aggrecanase, and the production of tumor necrosis factor (TNF). The anti-succinates are formed by an Ireland Claisen rearrangement of a silyl ketene acetal which proceeds with high stereoselectivity.
    Type: Application
    Filed: July 31, 2001
    Publication date: January 31, 2002
    Inventors: Roberta L. Dorow, Silvio Campagna, Pasquale N. Confalone, Fuqiang Jin, Zhe Wang
  • Patent number: 6235833
    Abstract: A water-repellent solution for forming a superior water-repellent film on a glass substrate is produced by subjecting a fluoroalkyl-group contained silane compound to a hydrolysis and a condensation polymerization. With this, at least dimers and trimers of the silane compound are produced. In case wherein the fluoroalkyl-group contained silane compound is of a type having the following general formula, satisfied performance of the formed water-repellent film is expected: CF3(CF2)m(CH2)2SiX3 wherein “m” is equal to or greater than 7 (seven) and “X” represents halogen, isocyanate-group or alkoxy-group, said alkoxy-group including methoxy-group [OCH3], ethoxy-group [OC2H5] or isopropoxy-group [OC3H5]. When the “m” is equal to or greater than 9 (nine), the performance of the film is much increased.
    Type: Grant
    Filed: February 12, 1999
    Date of Patent: May 22, 2001
    Assignee: Central Glass Company, Limited
    Inventors: Yoshinori Akamatsu, Shigeo Hamaguchi
  • Patent number: 6218498
    Abstract: The invention relates to organosilicon compounds with at least three silicon atoms, consisting of units of the formula (I) RaSi(NR1C═ONR22)k(NR3C═ONR4)t/2YmOn/2[(CR52)s]r/2, where Y represents units of the formula (II) —SiR63-p-q(NR1C═ONR22)p(NR3C═ONR4)q/2, where R, R1, R2, R3, R4, R5 and R6 independently of each other can be either identical or different and represent a hydrogen atom or possibly substituted monovalent hydrocarbon radicals with between 1 and 20 carbon atoms; and where a, k, t, n, m, r, s, p and q have the meaning assigned to them in claim 1, under the provision that the sum of p+q is ≦3, the sum of a+k+l+m+n+r equals 4, the sum of m+r equals 0 or 1, and the organosilicon compound of the invention contains at least one unit of formula (I) where t is not equal to 0.
    Type: Grant
    Filed: May 24, 1999
    Date of Patent: April 17, 2001
    Assignee: Wacker-Chemie GmbH
    Inventors: Stefan Oberneder, Wolfgang Hechtl, Erich Pilzweger, Doris Filusch, Michael Stepp
  • Patent number: 6211393
    Abstract: Silicon compound of general formula a), in which A, B, C, D are radicals which are different from OH and are covalently bonded to Si; two or three of these bond that are linked to Si are Si—O—C, Si—S—C or Si—N—C type bonds and are hydrolyzable in vivo, forming Si—OH bonds that are biologically active especially when in contact with living tissue, the A and D bonds of formula b) being invariably hydrolyzable; at least one of the hydrolyzable bonds corresponds to an acyloxy, aryloxy or vinyloxy radical; at least one of the compounds obtained after hydrolysis of the hydrolyzable bonds is a stabilizer, and the non-hydrolyzable bonds, which are of the Si—C type, correspond to hydrocarbon or fluorocarbon radicals for which Si is not directly linked to the phenyl ring.
    Type: Grant
    Filed: July 22, 1996
    Date of Patent: April 3, 2001
    Assignee: Exsymol S.A.M.
    Inventors: Marie Christine Seguin, Jean Gueyne, Jean-Francois Nicolay, Andre Franco
  • Patent number: 6172250
    Abstract: A process for the preparation of biologically active silicon compounds by hydrolysis of a precursor which produces a compound which prevents the formation of polymers from the silicon hydrolyzed bonds.
    Type: Grant
    Filed: July 16, 1996
    Date of Patent: January 9, 2001
    Assignee: Exsymol S.A.M.
    Inventors: Marie-Christine Seguin, Jean Gueyne, Jean-Francois Nicolay, Andre Franco
  • Patent number: 6160147
    Abstract: A compound of formula (I) is disclosed for use as a silylating agent: ##STR1## wherein each R.sup.1 is independently a hydrogen atom, an alkyl group or an alkenyl group with at least one R.sup.1 being a hydrogen atom or alkenyl group, and R.sup.2 is a hydrogen atom or an alkyl group. Also disclosed is a method of making the compound, and a method of using the compound as a silylating agent.
    Type: Grant
    Filed: December 9, 1999
    Date of Patent: December 12, 2000
    Assignee: Dow Corning Limited
    Inventors: Eric Damme, Jean de la Cro Habimana, Fabrice Lebecq, David Wilson
  • Patent number: 6130348
    Abstract: The present invention relates to a new method for making compounds of formula ##STR1## and intermediates for making compounds of formual II. The compounds of this invention are useful intermediates for the manufacture of pharmacologically active compounds suitable for the treatment of viral infections, particularly, those caused by HIV and other retroviruses.
    Type: Grant
    Filed: March 19, 1998
    Date of Patent: October 10, 2000
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Hans Hilpert
  • Patent number: 5959057
    Abstract: There is disclosed a polyorganosiloxane and a method for the preparation thereof, said polyorganosiloxane having the formula ##STR1## in which R is independently selected from substituted or unsubstituted monovalent hydrocarbon groups, m is an integer having a value of 0 to 500, n is an integer having a value of 0 to 500 and X is selected from a substituted or an unsubstituted monovalent hydrocarbon group or a hindered phenol group which is linked through either a carboxylate ester or an amide moiety, with the proviso that at least one of the X groups is said hindered phenol group.
    Type: Grant
    Filed: January 20, 1998
    Date of Patent: September 28, 1999
    Assignee: Dow Corning Toray Silicone Co., Ltd.
    Inventors: Haruhiko Furukawa, Koji Nakanishi
  • Patent number: 5532398
    Abstract: Silanes of the general formula (I):{X.sub.a R.sub.b Si(R'(A).sub.c).sub.(4-a-b) }.sub.x B (I)in which the groups and indices have the following meaning:X: hydrogen, halogen, hydroxy, alkoxy, acyloxy, alkyl carbonyl, alkoxycaryl or --NR".sub.2 ;R: alkyl, alkenyl, aryl, alkaryl, or aralkyl;R': alkylene, arylene or alkylene arylene;R": hydrogen, alkyl or aryl;A: O, S, PR", POR", NHC(O)O or NHC(O)NR";B: straight chain or branched organic group, which is derived from a B' compound with at least one C.dbd.C double bond for c.dbd.1 and A.dbd.NHC(O)O or NHC(O)NR") or at least two C.dbd.C double bonds, and 5 to 50 carbon atoms;a: 1, 2 or 3;b: 0, 1 or 2;c: 0 or 1;x: whole number, whose maximum value corresponds to the number of double bonds in compound B' minus 1, or is equal to the number of double bonds in compound B', when c.dbd.
    Type: Grant
    Filed: December 29, 1994
    Date of Patent: July 2, 1996
    Assignee: Fraunhofer-Gesellschaft zur Forderung der angewandten Forschung e.V.
    Inventors: Herbert Wolter, Klaus Rose, Christian Egger
  • Patent number: 5399738
    Abstract: Silanes of the general formula (I):{(X.sub.a R.sub.b Si(R'(A).sub.c).sub.(4-a-b) }.sub.x B (I)in which the groups and indices have the following meaning:X: hydrogen, halogen, hydroxy, alkoxy, acyloxy, alkyl carbonyl, alkoxycaryl or --NR".sub.2 ;R: alkyl, alkenyl, aryl, alkaryl, or aralkyl;R': alkylene, arylene or alkylene arylene;R": hydrogen, alkyl or aryl;A: O, S, PR", POR", NHC(O)O or NHC(O)NR";B: straight chain or branched organic group, which is derived from a B' compound with at least one C.dbd.C double bond for c=1 and A=NHC(O)O or NHC(O)NR") or at least two C.dbd.C double bonds, and 5 to 50 carbon atoms;a: 1, 2 or 3;b: 0, 1 or 2;c: 0 or 1;x: whole number, whose maximum value corresponds to the number of double bonds in compound B' minus 1, or is equal to the number of double bonds in compound B', when c=1 and A stands for NHC(O)O or NHC(O)NR";are suitable to prepare homo and copolycondensates and homo or copolymers according to the sol-gel method or by photochemical or thermal polymerization.
    Type: Grant
    Filed: April 5, 1991
    Date of Patent: March 21, 1995
    Assignee: Fraunhofer-Gesellschaft zur Forderung der Angewandten Forschung E.V.
    Inventors: Herbert Wolter, Klaus Rose, Christian Egger
  • Patent number: 5264603
    Abstract: A polydimethylsiloxane which has both low reactivity endgroups and high reactivity endgroups. These polydimethylsiloxanes are useful for making sealants with reduced modulus. An example of these polydimethylsiloxanes is one having low reactivity endgroups of the formulaXR.sub.2 SiO--where X is methoxy or methylethylketoximo, and R is methyl or vinyl and high reactivity endgroups having a formulaY.sub.b R.sub.(3-b) SiO--in which b is 2 or 3, R is methyl radical, and each Y is a hydrolyzable group selected from the group consisting of a ketoximo group and methoxy.
    Type: Grant
    Filed: August 25, 1992
    Date of Patent: November 23, 1993
    Assignee: Dow Corning Corporation
    Inventors: Michael G. Altes, Louise C. Bergman, Jerome M. Klosowski, Virginia K. O'Neil
  • Patent number: 5227504
    Abstract: A silylating agent comprising an N-(trialkylsilyl)benzanilide having the following general formula: ##STR1## wherein R.sup.1 is a lower alkyl group. This agent is reacted with a secondary amine to produce an N,N-dialkylaminotrialkylsilane. This process is free of formation of amine hydrochlorides as by-products. Therefore, the problem associated with disposal of such amine hydrochlorides and the problem of limitations on the use of the silane compound product due to mixing of such amine hydrochlorides can be obviated effectively.
    Type: Grant
    Filed: May 14, 1992
    Date of Patent: July 13, 1993
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Toshio Shinohara, Muneo Kudo, Kazuyuki Matsumura
  • Patent number: 5162559
    Abstract: A silylation reagent is useful for preparing binders which are soluble in aqueous alkali and contain silanyl groups in the side chain, comprises a compound having the formula I(A-B.sub.n).sub.m C (I)whereinA denotes a silanyl group containing at least 2 silicon atoms in total linked to each other, but not more than 3 silicon atoms linked to each other in an unbranched chain of silicon atoms;B denotes a bridging group;C denotes a functional group which is capable of forming a covalent bond with an aromatic, aliphatic or cycloaliphatic hydroxyl group;n denotes 0 or 1; andm denotes 1 or 2.Binders prepared with the silylation reagents described are soluble in aqueous alkali and exhibit a high resistance to plasma etching and a high storage stability, and are resistant to rediation with a wavelength of greater than 300 nm.
    Type: Grant
    Filed: April 3, 1989
    Date of Patent: November 10, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Peter Wilharm, Juergen Fuchs
  • Patent number: 5155228
    Abstract: A process is described for the improved synthesis of the optically pure C.sub.10 -C.sub.18 fragment of the macrolide structure of the immunosuppressant FK-506. This compound is also useful as an intermediate for preparing FK-506 derivatives.
    Type: Grant
    Filed: May 16, 1991
    Date of Patent: October 13, 1992
    Assignee: Merck & Co., Inc.
    Inventors: Todd K. Jones, Sander G. Mills, Richard Desmond
  • Patent number: 5079206
    Abstract: A catalyst for addition polymerization comprising:(a) an (initiator) first component of Formula (I):MX(Y.sub.n)Z.sub.p (I)whereinM is Si, Ge or Sn;n is O or an integer, and p is an integer such that (n+p)=3;X is a radical ##STR1## where Q and Q.sup.1 are each independently N, P or As;Q.sup.2 is O, S, NR or PR where R is C.sub.1-4 alkyl;R.sup.1 is H or optionally substituted hydrocarbyl; andR.sup.2 and R.sup.3 are each independently optionally substituted hydrocarbyl, or R.sup.2 and R.sup.3 together are optionally substituted aliphatic hydrocarbadiyl;all such R.sup.1, R.sup.2 and R.sup.3 being inert in the process conditions of the present invention;Y is A or OA where A is optionally substituted hydrocarbyl inert in the process conditions of the present invention, or trialkylsilylalkyl; andZ is independently any group as definedd for Y, or an organic polymer radical comprising further MXY.sub.n moieties; orp is 2 andZ.sub.2 is a group Z.sup.1 .sub.2 of the formula --OSiR.sup.5 R.sup.8 O-- where R.sup.5, R.sup.
    Type: Grant
    Filed: June 25, 1990
    Date of Patent: January 7, 1992
    Assignee: Imperial Chemical Industries plc
    Inventors: Denis G. H. Ballard, Anthony Pickering, Peter J. I. Runciman, Rowena J. Sellens, Nicholas J. Walton
  • Patent number: 5049689
    Abstract: Described is a novel process for the introduction of an organic acyl radical selectively at the nitrogen atom of the amino group of desferrioxamine B or of a partially O-acylated derivative thereof. It comprises treating a derivative of desferrioxamine B, in which the amino nitrogen and the hydroxy oxygen of at least one of the hydroxamic acid groupings carries an organic silyl group, with an organic acylating agent and then removing the silyl groups present. The novel N- and O-silylated starting materials can be manufactured, preferably in situ, by reacting an appropriate derivative of desferrioxamine B that has at least one hydroxy group and the amino group in free form, with an organic silicon halide.
    Type: Grant
    Filed: January 23, 1990
    Date of Patent: September 17, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Heinrich Peter, Theophile Moerker
  • Patent number: 5021600
    Abstract: A new mono-silylating agent of general formula (I)(R.sub.1,R.sub.2,R.sub.3)Si--NH--CO--O--Si(R.sub.1,R.sub.2,R.sub.3) (I)is described as well as its use in the preparation of chromatographic supports based on silica with functional groups covalently bonded thereto, the so-called "bonded stationary phases".The new compounds are easy and safe to prepare from the coresponding mono-halosilanes with ammonium carbamate, and their use as silylating agents leads to stationary phases with a higher degree of surface coating than that attainable with the corresponding chlorosilanes.
    Type: Grant
    Filed: August 15, 1989
    Date of Patent: June 4, 1991
    Assignees: Eniricerche S.p.A., Sclavo S.p.A.
    Inventors: Franco Cardinali, Maria G. Longobardi, Giuseppe C. Viscomi, Alessandra Ziggiotti
  • Patent number: 4871646
    Abstract: Disclosed are a polysilane containing a unit represented by the following formulas I, II, or III, and a photosensitive composition consisting of the polysilane.
    Type: Grant
    Filed: May 13, 1988
    Date of Patent: October 3, 1989
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Shizu Hayase, Rumiko Horiguchi, Yasunobu Onishi, Toru Ushirogouchi
  • Patent number: 4789742
    Abstract: Novel Isomaleimido and isophthalimido derivatives of chromophoric compounds are provided which are useful in analytic techniques for the detection and measurement of biological compounds such as bacteria, enzymes, hormones and the like.
    Type: Grant
    Filed: July 14, 1986
    Date of Patent: December 6, 1988
    Inventor: Spyros Theodoropulos
  • Patent number: 4767876
    Abstract: A method of forming preceramic polymers using an organosilicon polymer containing Si--H repeat units by reacting it with alkali metal amide or silylamide is disclosed. Preferably, the silylamide is a polymeric silylamide formed by reacting in solution anhydrous ammonia with a mixture of R.sup.1 SiHX.sub.2 (where R.sup.1 is a lower alkyl group having from 1 to about 6 carbon atoms, a substituted or unsubstituted cycloalkyl group having from 3 to about 6 carbon atoms, a substituted or unsubstituted lower alkenyl group having from 2 to about 6 carbon atoms or a substituted or unsubstituted lower aryl group having from 6 to about 10 carbon atoms; and X is a halogen) and R.sup.2 SiX.sub.3 (where R.sup.
    Type: Grant
    Filed: October 7, 1986
    Date of Patent: August 30, 1988
    Assignee: Massachusetts Institute of Technology
    Inventors: Dietmar Seyferth, Joanne M. Schwark, Yuan-Fu Yu
  • Patent number: RE32717
    Abstract: N-Methyl-N-trimethylsilyl trifluoroacetamide can be synthesized by the reaction of N-methyl trifluoroacetamide and, N,O-bis(trimethylsilyl) acetamide at 40.degree.-130.degree. C. followed by fractionating distillation. The method is advantageous in respect of the absence of the step of filtration for the removal of the by-product salt and non-use of any corrosive reactant in comparison with conventional methods.
    Type: Grant
    Filed: October 19, 1987
    Date of Patent: July 19, 1988
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Toshio Shinohara, Yoshifumi Inoue