Plural Phosphori Attached Indirectly To Each Other By A Benzene Ring Or By A Chain Which Includes A Benzene Ring Patents (Class 558/162)
  • Patent number: 5506313
    Abstract: The invention relates to compounds of the formula (1) ##STR1## in which m is 0 or 1,R is a hydrogen atom or a group of formula ##STR2## T is either an (m+2)-valent aromatic group or a bisphenylene group, [Z] is a group of on average 1 to 10 structural units of the formula (3)--Q--T(OR).sub.1+m-r (EB).sub.r (3),in whichQ is a group of the formula (4) ##STR3## in which R.sup.0 is a phenyl radical substituted in a particular manner andR.sup.1 andR.sup.2 are C.sub.1 -C.sub.4 alkyl, and in which, furthermore,EB symbolizes a free valency of the group T,r has one of the values 0, 1 or 1+mand the structural units of the formula (3) are linked via their free valencies to the group [Z] such that the groups Q in each case alternate with groups T and the group [Z] overall is monovalent. As excellent flameproofing agents which are reactive towards epoxy compounds, the compounds are a useful formulation component for epoxy resin compositions.
    Type: Grant
    Filed: September 7, 1994
    Date of Patent: April 9, 1996
    Assignee: Ciba-Geigy Corporation
    Inventors: Peter Flury, Carl W. Mayer, Wolfgang Scharf, Ennio Vanoli
  • Patent number: 5476888
    Abstract: The diposphines have the formula (I) ##STR1## wherein: R.sup.2, R.sup.3 and R.sup.4 independently from each other represent a hydrocarbyl group which is substituted with one or more radicals selected from the group consisting of halogen, alkyl and alkoxy, andA is --C(O)--, --S(O).sub.2 --, --S(O)-- or certain divalent organic groups.The diphosphines are useful for stabilizing thermoplastic polymers, such as polycarbonates, against thermal discoloration.
    Type: Grant
    Filed: September 2, 1994
    Date of Patent: December 19, 1995
    Assignee: The Dow Chemical Company
    Inventors: Jurgen Eiffler, Gunter A. Juptner, David P. Flores
  • Patent number: 5438047
    Abstract: Diphosphates of catecholamines having formula (I) wherein R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and X have the meanings reported in the description, are useful in the therapy of cardiovascular and renal diseases.
    Type: Grant
    Filed: March 28, 1994
    Date of Patent: August 1, 1995
    Assignee: Zambon Group S.p.A.
    Inventors: Francesco Santangelo, Cesare Casagrande, Gabriele Norcini
  • Patent number: 5420327
    Abstract: Hydrocarbyl bisphosphate compounds containing hindered aryl substituents in the phosphate groups can be formed by: (a) reacting a hindered phenol, e.g., xylenol, with a phosphorus oxytrihalide, e.g., phosphorus oxytrichloride, to form a reaction product mixture; and (b) combining the reaction product, without distillation of the product from the reaction product mixture, from (a) mixture with a hydrocarbyl diol, e.g., one containing a phenyl ring such as hydroquinone or resorcinol.
    Type: Grant
    Filed: September 10, 1993
    Date of Patent: May 30, 1995
    Assignee: Akzo Nobel N.V.
    Inventors: Danielle A. Bright, Ronald L. Pirrelli
  • Patent number: 5393748
    Abstract: Novel pharmacologically active methylenebisphosphonates having formula (I) wherein R.sup.1 -R.sup.4 independently are C.sub.1 -C.sub.10 -alkyl, C.sub.3 -C.sub.10 -cycloalkyl, aryl, aralkyl, silyl SiR.sub.3 or hydrogen, whereby in formula (I) at least one of the groups R.sup.1 -R.sup.4 is hydrogen and at least one of the groups R.sup.1 -R.sup.4 is different from hydrogen, Q.sup.1 is hydrogen, hydroxyl, halogen, amino NH.sub.2, or OR'.sub.1, wherein R'.sub.1 is C.sub.1 -C.sub.4 -alkyl or acyl, Q.sup.2 is the group (.alpha.) wherein Y is a six-membered heterocyclic group, or a carbocyclic aromatic group, X is a bond, O, S or NR'", wherein R'" is hydrogen, lower alkyl, or acyl, n is the integer 0 to 6, and R' and R" are hydrogen or lower alkyl provided that as a ring atom of the ring Y and/or a chain atom of the group X, there is always at least one heteroatom from the group O, N and S, including the steroisomers and the salts of the compounds.
    Type: Grant
    Filed: October 20, 1993
    Date of Patent: February 28, 1995
    Assignee: Leiras Oy
    Inventors: Esko Pohjala, Marjaana Heikkila-Hoikka, Hannu Nikander, Hannu Hanhijarvi
  • Patent number: 5387352
    Abstract: Novel aromatic polyphosphate ester-acids and amine salts thereof are described. These products are eminently useful as ashless antiwear agents in lubricating oils.
    Type: Grant
    Filed: November 26, 1993
    Date of Patent: February 7, 1995
    Assignee: Ethyl Corporation
    Inventor: Ramnath N. Iyer
  • Patent number: 5347040
    Abstract: Onium salt capable of generating acid upon exposure to actinic radiation having the following structure:(R.sub.1).sub.a (R.sub.2).sub.b (R.sub.3).sub.c Q.sup.+ --A--M.sup.+ X.sup.- --B--X'.sup.-where:Q is S;R.sub.1, R.sub.2 and R.sub.3 are independently substituted or unsubstituted aromatic, aliphatic, or aralkyl groups having 7-18 carbon atoms;M.sup.+ is a cationic organic radical;A is a divalent radical selected from the group of hindered alkylene groups, substituted or unsubstituted aromatic or aralkyl groups;B is a divalent aromatic sensitizer which absorbs radiation having a wavelength longer than 300 nm and is capable of transferring an electron to Q,x.sup.- and X'.sup.- are anionic groups; and wherein A provides a spatial separation between Q and M, and B provides a spatial separation between X and X', such that the spatial separation provided by A between Q and M is substantially the same as the spatial separation provided by B between X and X'.
    Type: Grant
    Filed: December 9, 1992
    Date of Patent: September 13, 1994
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Arnost Reiser, Xiaohua He
  • Patent number: 5342869
    Abstract: A composition, having good weatherability properties, comprisinga) one or more compounds of formula I ##STR1## in which m is 1;n is 0 or 1;p is 0;each R or R.sup.1 independently, is a group derived from an aliphatic, alicyclic or aromatic alcohol containing one or two OH groups; whereby the two --OH groups are not positioned to be able to form a P-containing ring;or both groups R form a group derived from an aliphatic, alicyclic or aromatic alcohol containing two OH groups in such a position that they can form a cyclic group with a single phosphorus atom;Y is --O--, --S--, --CH(R.sub.5)-- or --C.sub.6 H.sub.4 --;where R.sub.5 is hydrogen or C.sub.1-8 alkyl or COOR.sub.6 and R.sub.6 is C.sub.1-8 alkyl; andb) a polymeric material.
    Type: Grant
    Filed: July 6, 1992
    Date of Patent: August 30, 1994
    Assignee: Sandoz Ltd.
    Inventors: Klaus Stoll, Rainer Wolf
  • Patent number: 5328621
    Abstract: The invention relates to novel compounds of formulae I, II and III ##STR1## wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.20 alkyl or C.sub.5 -C.sub.7 cycloalkyl, R.sub.2 is hydrogen, C.sub.1 -C.sub.20 alkyl or C.sub.5 -C.sub.7 cycloalkyl, and R.sub.3 is C.sub.1 -C.sub.18 alkyl or C.sub.3 -C.sub.18 alkenyl. The compounds are used as antiwear additives for lubricants.
    Type: Grant
    Filed: October 21, 1993
    Date of Patent: July 12, 1994
    Assignee: Ciba-Geigy Corporation
    Inventors: Hugo Camenzind, Paul Dubs
  • Patent number: 5312954
    Abstract: Novel bisphosphonates comprise compounds of the formula (I) ##STR1## wherein m and l are independently 1 or 2; R.sub.1 represents hydrogen, a lower alkyl group, or an alkali metal cation; R.sub.2 represents hydrogen, a lower alkyl group or an alkali metal cation; Y represents .dbd.0 or .dbd.N--OH, or --OH and X represents --(CH.sub.2).sub.n --, a branched alkylene group, or a branched or straight alkenylene or alkynylene chain optionally substituted by one or more oxygen or nitrogen atoms, wherein n is an integer from 3 to 24. Further definitions of X are included in the description.
    Type: Grant
    Filed: May 13, 1992
    Date of Patent: May 17, 1994
    Assignee: Yissum, Research Development Company of the Hebrew University of Jerusalem
    Inventors: Eli Breuer, Gershon Golomb
  • Patent number: 5302738
    Abstract: Novel, racemic and optically active phosphorus compounds of the formula ##STR1## wherein R signifies lower alkyl, lower alkoxy or protected hydroxy, R.sup.1 signifies lower alkoxy, phenoxy, benzyloxy, chlorine or bromine, R.sup.2 stands for lower alkyl or lower alkoxy and n represents the number 0, 1 or 2, are described. These compounds are valuable intermediates in the manufacture of not only known, but also novel diphosphine ligands.
    Type: Grant
    Filed: November 13, 1992
    Date of Patent: April 12, 1994
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Joseph Foricher, Bernd Heiser, Rudolf Schmid
  • Patent number: 5278212
    Abstract: A flow modifier for a thermoplastic resin, which is a hydroxyphenyl-containing organophosphorus compound represented by formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, and R.sub.4 each represents a hydroxyl group, ##STR2## a hydrogen atom, or an alkyl group having 1 to 6 carbon atoms; a, b, c, and d each represents an integer of from 1 to 3; n represents 0 or an integer of from 1 to 3; when n is 0 or 1, the compound contains one hydroxyl group or ##STR3## group per molecule; and when n is 2 or 3, the compound contains one or two, in total, of hydroxyl group and ##STR4## group per molecule and thermoplastic resin composition containing the flow modifier is disclosed.
    Type: Grant
    Filed: October 13, 1992
    Date of Patent: January 11, 1994
    Assignee: Asahi Kasei Kogyo Kabushiki Kaisha
    Inventors: Hajime Nishihara, Katsuaki Maeda, Hiroaki Ishikawa, Hiroshi Mikami
  • Patent number: 5227506
    Abstract: The invention relates to acyloxymethyl esters of bisphosphonic acids, halo-bisphosphonic acids and hydroxy-bisphosphonic acids which exhibit oral bioavailability and are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.
    Type: Grant
    Filed: July 12, 1990
    Date of Patent: July 13, 1993
    Assignee: Merck & Co., Inc.
    Inventors: Walfred S. Saari, Paul S. Anderson
  • Patent number: 5217964
    Abstract: The present invention relates to certain polyamine thiols which are useful as radioprotective agents.
    Type: Grant
    Filed: January 23, 1991
    Date of Patent: June 8, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: Michael L. Edwards, Ronald D. Snyder
  • Patent number: 5173431
    Abstract: A procedure for detecting proteins in fluids (particularly body fluids) which involves contacting such fluid with a composition comprising copper in a form capable of forming a copper/protein complex, a peroxide and a redox indicator which provides a detectable response when oxidized, together with an ionizable phosphate containing compound to prevent interference with the redox indicator from substances present in the fluid.
    Type: Grant
    Filed: October 12, 1991
    Date of Patent: December 22, 1992
    Assignee: Miles Inc.
    Inventors: Michael J. Pugia, Michael Salvati
  • Patent number: 5084592
    Abstract: Azulenesquaric acid dyes of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 each have specified meanings are prepared from azulene derivatives of the formula ##STR2## where R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 each have specified meanings as intermediates, and used in an optical recording medium.
    Type: Grant
    Filed: September 30, 1988
    Date of Patent: January 28, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Wolfgang Schrott, Peter Neumann, Sibylle Brosius, Helmut Barzynski, Klaus D. Schomann, Harald Kuppelmaier
  • Patent number: 4924023
    Abstract: A process for regioselectively preparing phosphorylated cyclitols, in particular phosphorylated inositols such as myo-inositol 1,4,5-tris(phosphate) and myo-inositol 1,3,4,5-tetrakis(phosphate). Novel cyclitols produced by means of this process are also described.
    Type: Grant
    Filed: June 27, 1989
    Date of Patent: May 8, 1990
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Frank W. Hobbs, James L. Meek
  • Patent number: 4898944
    Abstract: Precursors for the preparation of fiber-reactive triphendioxazine dyestuffs correspond to the general formulas: ##STR1## in which Y' is a vinyl, a beta-hydroxyethyl or an ethyl group which contains in the beta-position a substituent which can be eliminated by an alkali;T is an optionally substituted alkyl (e.g.
    Type: Grant
    Filed: October 27, 1988
    Date of Patent: February 6, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Gunther Schwaiger, Hartmut Springer, Walter Helmling
  • Patent number: 4853455
    Abstract: The present invention relates to hardenable mixtures containing:(i) a polyglycidyl ether or ester based on an aliphatic, cycloaliphatic or aromatic alcohol or a corresponding carboxylic acid and(ii) a hardener obtainable by reaction of:(A) a mixture of 2-4 mol of a monohydric, aliphatic alcohol and 1 mol of phosphorus pentoxide in an inert organic solvent, or of 2 mol of a dialkyl phosphate or of 2 mol of phosphoric acid, if appropriate in combination with 1-2 mol of a monohydric, aliphatic alcohol, with(B) 0.5-1.5 mol of a diglycidyl ether based on a cycloaliphatic or aromatic diol,with the proviso that the said diglycidyl ether used for the preparation of the hardener has an average molecular weight (number-average) of not more than 2,500 and the said hardener is essentially free from 1,2-epoxide groups.The hardenably mixtures are suitable in particular for the production of coatings.
    Type: Grant
    Filed: May 6, 1988
    Date of Patent: August 1, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Wolfgang Schneider, Kurt Amsler
  • Patent number: 4837276
    Abstract: The invention relates to oligomeric and polymeric esters of difunctional polyphenylene ethers and phosphinic acids, phosphonic acids and phosphoric acid and to their use as a flame-retarding mixing component for other plastics.
    Type: Grant
    Filed: December 28, 1987
    Date of Patent: June 6, 1989
    Assignee: Bayer Aktiengesellschaft
    Inventors: Karl Fuhr, Friedemann Muller, Karl-Heinz Ott
  • Patent number: 4814448
    Abstract: Certain phenyl and N-heterocyclic phosphorothioates and phosphates are prepared by the reaction of an appropriate alkali metal or alkaline earth metal -O-phenyl or N-heterocyclic compound with an appropriate phosphorochloridate or phosphorochloridothioate under alkaline conditions in a liquid reaction medium and in the presence of a tertiary amine catalyst and a nonionic surfactant having a HLB Value of from about 2.5 to about 20 or more.
    Type: Grant
    Filed: March 6, 1987
    Date of Patent: March 21, 1989
    Assignee: The Dow Chemical Company
    Inventors: Sterling C. Gatling, Karl L. Krumel
  • Patent number: 4814451
    Abstract: Certain phenyl and N-heterocyclic phosphorothioates and phosphonothioates and phosphates are prepared by the reaction of an appropriate alkali metal or alkaline earth metal --0-phenyl or N-heterocyclic compound with an appropriate phosphorochloridate, phosphorochloridothioate, phosphonochloridate or phosphonochloridothioate under alkaline conditions in the presence of a tertiary amine catalyst and a nonionic surfactant having an HLB Value of from about 1 to about 20, preferably about 5 to 15, in a two-phase system, one phase being primarily the phosphorate or phosphonate reactant and a complex thereof with the tertiary amine catalyst and the other phase being an aqueous reaction medium comprising water, a buffer system, and the alkali metal or alkaline earth metal-O-phenyl or --O-N-heterocyclic compound, in the substantial or complete absence of an organic solvent the aqueous reaction medium being maintained at pH about 10 to 12 by the buffer system.
    Type: Grant
    Filed: March 20, 1987
    Date of Patent: March 21, 1989
    Assignee: The Dow Chemical Company
    Inventor: Sterling C. Gatling
  • Patent number: 4724247
    Abstract: An aromatic diphosphite as a antioxidant for organic materials. The aromatic diphosphite has the formula: ##STR1## wherein each R is independently selected from the group consisting of hydrogen and methyl; and R.sup.1, R.sup.2 and R.sup.3 are each independently selected from the group consisting of hydrogen and straight chain and branched alkyl groups having from 1 to about 18 carbon atoms with the proviso that at least two of said R.sup.1, R.sup.2, and R.sup.3 are alkyl groups having at least three carbon atoms.
    Type: Grant
    Filed: July 18, 1986
    Date of Patent: February 9, 1988
    Assignee: Ethyl Corporation
    Inventors: Lester P. J. Burton, Kestutis A. Keblys, Ronald L. Shubkin
  • Patent number: 4696920
    Abstract: 2-Substituted-1,3-propylidenediphosphonates of formula (I), where A, R.sup.1 and R.sup.2 are defined in claim 1, are therapeutically active compounds, namely for the treatment of cardiovascular diseases.They can be prepared by reacting phosphonating agents with 1,3- dibromopropanes or ditosylates of 1,3-propanediols substituted in position 2. ##STR1## .
    Type: Grant
    Filed: July 16, 1985
    Date of Patent: September 29, 1987
    Assignee: Symphar S.A.
    Inventors: Craig L. Bentzen, Yves Guyon-Gellin, Kyriacos Kalathakis, Hieu T. Phan, Lan Nguyen Mong, Eric Niesor, Jean-Robert Rossier
  • Patent number: 4681965
    Abstract: A class of Mannich condensates containing phosphorus prepared by reacting a phenol with formaldehyde and a primay amine, and then reacting the product with formaldehyde and a dialkyl phosphite. Useful applications include use as a fire retardant additive in polyurethane foams.
    Type: Grant
    Filed: August 8, 1985
    Date of Patent: July 21, 1987
    Assignee: Texaco Inc.
    Inventors: George P. Speranza, Michael E. Brennan, Robert A. Grigsby, Jr.
  • Patent number: 4659856
    Abstract: Compounds of the general formula (1) ##STR1## in which the Zs, preferably identical to each other, each denote a hydroxy group or a sulfato, thiosulfato or phosphato group. They can be prepared by first converting biphenyl by sulfochlorination into biphenyl-4,4'-disulfochloride, then reducing the latter with an alkali metal or alkaline earth metal sulfite or hydrogensulfite to sulfinic acid, and in turn reacting the latter with ethylene oxide to give 4,4'-bis-(.beta.-hydroxyethylsulfonyl)-biphenyl, which can be esterified in conventional manner. They are used for modifying and improving the physical and coloristic properties of materials made of natural and/or synthetic polyamide fibers and/or polyurethane fibers and as auxiliaries in dyeing processes for such fiber materials.
    Type: Grant
    Filed: September 12, 1985
    Date of Patent: April 21, 1987
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hartmut Springer, Gerd Konig
  • Patent number: 4650609
    Abstract: Compounds having a quinodimethane or a 7,8-dihydroquinodimethane nucleus and four substituted phosphinyl groups at the 7- and 8-positions are disclosed. A process for preparing the specified compounds is also disclosed.
    Type: Grant
    Filed: June 25, 1985
    Date of Patent: March 17, 1987
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: David R. Brittelli