Abstract: The present invention relates to a novel process for preparation of 2-Cyano-3,3-diarylacrylates by the Knoevenagel condensation of Cyanoacetic esters and Arylketones using ammonium compound and acetic acid and without the use of organic solvent.

Abstract: Porous metal-organic frameworks (MOFs) and metallated porous MOFs are provided. Also provided are methods of metallating porous MOFs using atomic layer deposition and methods of using the metallated MOFs as catalysts and in remediation applications.

Abstract: The present invention relates to the preparation of a solid catalytic composition based on a functionalized porous organic material, wherein: (A) organogelator compounds are self-assembled, within a medium comprising organic monomers, in the form of fibrillar structures having a diameter ranging from 10 nm to 100 nm; and then (B) the monomers are then polymerized; and then (C) the organogelator compounds are extracted from the polymer material, thereby obtaining a porous polymer material (M0), wherein the monomers bear reactive R functions, for which the presence is sought on the material; or said reactive R functions in protected form; or functions able to allow grafting of said reactive R functions on the polymer materials; and wherein, following step (C), (D) all or part of the functions present at the walls of the mesopores of the polymer material (M0) are converted where appropriate into reactive R functions and a composition is recovered comprising a porous polymer material (M) bearing the reactive R fu

Abstract: This invention relates to novel imines, some of which are in the form of ionic liquids, and a process for producing electron deficient olefins, such as 2-cyanoacrylates, using an imine, for instance such novel imines, many of which are in the form of an ionic liquid.

Abstract: The invention relates to an improved process for the manufacture of substituted 2-cyanocinnamic esters. This novel economical process provides products in high purity and yields.

Abstract: A process for the preparation of entacapone, in particular as the polymorphic form A, comprising the preparation of a compound of formula (V), wherein R is C1-C6 alkyl, by condensation of N,N-diethyl-cyano-acetamide with a compound of formula (IV), wherein R is C1-C6 alkyl, in the presence of a strong basic agent; the dealkylation of the compound of formula (V) to obtain entacapone, and the crystallization thereof from methyl ethyl ketone is performed to yield the polymorphic form A. The polymorphic form A of entacapone may be used to treat Parkinson's disease and/or to enhance effectiveness of muscle control.

Abstract: Process for the preparation of 4-fluoroalkoxycinnamonitriles.The invention relates to a process for the preparation of fluoroalkoxycinnamonitriles of the formula (I) ##STR1## in which n is 1 to 8 and m is 1 to 17, where m.ltoreq.2n+1, by reacting 4-fluorobenzaldehyde with a fluoroalkanol of the formula (II)H.sub.2n+1-m F.sub.m C.sub.n O--H (II)in which m and n are as defined above, in the presence of a base and, if appropriate, a solvent, and reacting the resulting 4-fluoroalkoxybenzaldehyde with cyanoacetic acid or an alkyl cyanoacetate in the presence of a base and, if appropriate, a solvent.

Abstract: In the preparation of substituted 2-cyanocinnamic esters by the Knoevenagel condensation of cyanoacetic esters and carbonyl compounds, the reaction times for obtaining high yields can be considerably reduced by using C.sub.3 -C.sub.6 -monocarboxylic acids and ammonium compounds as catalysts.

Abstract: Described are substituted 2,6-dimethylbicyclo[3,3,1]- non-6-enes defined according to the generic structure: ##STR1## wherein the dashed line represents a carbon-carbon single bond or a carbon-carbon double bond and wherein "R" represents one of the moieties: ##STR2## processes for preparing same and uses thereof in augmenting or enhancing the aroma of consumable materials including perfume compositions, colognes and perfumed articles (e.g., solid or liquid anionic, cationic, nonionic or zwitterionic detergents, hair preparations, fabric softeners, fabric softener articles, cosmetic powders and perfumed polymers).

Abstract: A process for the preparation of arylidene dyes comprises the reaction of an aromatic amine with an enolate salt of a formylated active methylene compound in the presence of a sulfonyl halide compound. An enol sulfonate is postulated as a reactive intermediate in the reaction. The process gives high yields of products under mild reaction conditions and allows the use of aromatic groups containing substituents such as hydroxy that lead to side reactions and low product yields with previously known methods for making arylidene dyes.

Abstract: New nitriles which are odoriferous substances having an extremely fresh note are accessible by Knoevenagel condensation of 2-cyclopentyl-cyclopentanone and cyanoacetic acid and decarboxylation of the reaction product.

Abstract: Fluorene derivatives represented by the general formula (I): ##STR1## wherein R represents an alkyl group having 1 to 8 carbon atoms, a phenyl group of a C.sub.1 -C.sub.8 alkyl-substituted phenyl group, and a process for preparation thereof. These fluorene derivatives are synthesized by reacting fluorenone derivatives represented by the general formula (II): ##STR2## wherein R is the same as defined above, with malonitrile.

Abstract: Benzophenone derivatives which are useful in electrophotographic light-sensitive material represented by formula (I): ##STR1## wherein A represents the structural formula (a), (b) or (c): ##STR2## and R represents an alkyl group having 1 to 8 carbon atoms or a nitro group, and a process for preparation thereof. These benzophenone derivatives can be synthesized by reacting compounds represented by formula (II): ##STR3## wherein A and R are the same as defined above, with malonitrile.

Abstract: An improvement in a process for the industrial application of the Knoevenagel synthesis in an acid solution, resulting in a steady flow of waste gas.

Abstract: 13-oxabicyclo[10.3.0]pentadecane, a valuable ambergris fragrance, is prepared by reacting cyclododecanone with cyanoacetic acid in the presence of a Knoevenagel catalyst to form cyclododecenylacetonitrile, the nitrile is hydrolyzed to cyclododecenylacetic acid, and the acid is cyclized to the lactone, and the lactone is reduced to the corresponding diol which is cyclized to 13-oxabicyclo[10.3.0]pentadecane.

Abstract: An electron-accepting compound represented by the formula (I): ##STR1## wherein R represents a hydrogen atom or --B(Mes).sub.2 and Mes represents a mesityl group.A method for preparing an electron-accepting compound represented by the above-described formula (I), which comprises condensing a benzophenone derivative represented by the following formula (II) with malononitride, ##STR2## wherein R and Mes have the same meanings as defined for the formula (I).

Abstract: Alkylidene compounds and arylidene compounds are prepared by reacting the corresponding CH-acidic compounds with carbonyl compounds in the presence of a catalyst comprising a metal compound of a metal of Groups IIA, IIIA, IVA, IB, IIB, VIB, VIIB, or VIIIB of the periodic table of elements. The rate of reaction is increased by adding 1 to 40% water referred to the weight of catalyst used.

Abstract: .beta.-Dicarbonyl and .beta.-cyanocarbonyl compounds ##STR1## where R.sup.1 is alkyl of 1-20 carbons, X is --COR.sup.2, Y is --COOR.sup.3, --COR.sup.3 or --CN, and R.sup.2 and R.sup.3 are each C.sub.1 -C.sub.10 -alkyl, are prepared from R.sup.1 --CHO (II) and X--CH.sub.2 --Y (III) by reaction in the presence of a condensation catalyst, hydrogen and a hydrogenation catalyst, using an oxide or phosphate of Mg, Al, Ti, Zn or a rare earth metal as the condensation catalyst.

Abstract: Cyclododecenylacetonitrile is prepared by reacting cyclododecanone with cyanoacetic acid in the presence of a catalyst. Purified cyclododecenylacetonitrile has a pleasant scent reminiscent of roses and lilies of the valley, containing additionally a musk note, and is suitable as a fragrance and as a fragrance component.

Abstract: .beta.-Dicarbonyl, .beta.-cyanocarbonyl and .beta.-dicyano compounds I ##STR1## where R.sup.1 is an organic radical, X and Y are COOR.sup.2, --CO--R.sup.2 or --CN and R.sup.2 is an organic radical, are prepared from R.sup.1 --CHO (II) and X--CH.sub.2 --Y (III) by reaction in the presence of a condensation catalyst, hydrogen and a hydrogenation catalyst, using an oxide or phosphate of Mg, Al, Ti, Zn or a rare earth metal as the condensation catalyst.