Chalcogen Attached Indirectly To The Sulfonate Group By Acyclic Nonionic Bonding Patents (Class 558/51)
-
Patent number: 4931579Abstract: Indicators for the detection of thio groups are disclosed together with processes for the preparation of such indicators.Type: GrantFiled: November 7, 1989Date of Patent: June 5, 1990Assignee: Miles Inc.Inventors: Holger Heidenreich, Klaus Wehling
-
Patent number: 4918211Abstract: Novel surfactants of the formula: ##STR1## wherein R.sub.1 is alkyl, alkenyl or aralkyl of 4-18 carbon atoms, R.sub.2 is hydrogen or same as R.sub.1, R.sub.3 is hydrogen or methyl, A is alkylene of 2-4 carbon atoms, and n is 1-200. Sulfates, phosphates and sulfosuccinates thereof are also useful as anionic surfactants.Type: GrantFiled: November 10, 1987Date of Patent: April 17, 1990Assignee: Dai-Ichi Kogyo Seiyaku Co., Ltd.Inventors: Kinya Yokota, Akinobu Ichihara, Hitoshi Shinike
-
Patent number: 4873354Abstract: An iodophor having biocidal activity is disclosed which is a polyethylene glycol alkylarylsulfonate iodine complex. The complex is formed by reacting polyethylene glycol, alkylarylsulfonate and iodine, in the presence of water and propylene glycol as solvent under reflux conditions. This iodophor is characterized by a low iodine content, high sudsing properties, high biocidal activity, reduced vapor pressure, reduced odor and substantially non-existent staining.Type: GrantFiled: April 21, 1988Date of Patent: October 10, 1989Inventor: Alfred R. Globus
-
Patent number: 4851585Abstract: Novel methyl carbinol derivatives of Vitamin E and a method for their manufacture.Type: GrantFiled: November 12, 1987Date of Patent: July 25, 1989Assignee: Hoffmann-La Roche Inc.Inventors: Richard Barner, Josef Hubscher
-
Patent number: 4812589Abstract: The invention relates to a process for the production of sulphonic acid ester group-containing polyhydroxyl compounds having an average hydroxyl functionality of from 1.5 to 4, comprising reacting(a) paraffin sulphochlorides which are obtained by sulphochlorination of paraffins containing from 10 to 18 carbon atoms or of industrial mixtures of these paraffins, with unreacted paraffins and/or with chloroparaffins, having saponifiable chlorine content, based on the total weight of component (a), of from 5 to 15% with(b) an alcohol which is at least trihydric and which contains primary and/or secondary hydroxyl groups within the molecular weight range of from 92 to 250 or with mixtures of polyhydric alcohols having a molecular weight in the range of from 62 to 250 with an average hydroxyl functionality of from 2.Type: GrantFiled: September 17, 1986Date of Patent: March 14, 1989Assignee: Bayer AktiengesellschaftInventors: Klaus Prater, Walter Uerdingen, Heinrich Heine, Dieter Freitag
-
Patent number: 4758362Abstract: A phosphorus free or a low phosphorus containing lubricant composition is provided by formulating the composition with an additive of the formula ##STR1## wherein R.sub.1 and R.sub.2 are independently alkyl of 1 to about 7 carbons, aryl, aralkyl or together form an alicyclic or heteroalicyclic radical in which the ring is completed through the nitrogen; X is O or S; a is 1 or 2; R.sub.3 and R.sub.4 are independently H, alkyl or aryl; and Z is ##STR2## wherein R.sub.5 is hydrogen, alkyl, or aralkyl, and ##STR3## wherein Y is H, OH, R.sub.6 where R.sub.6 is alkyl, aryl or aralkyl, OR.sub.6, OR.sub.7 --OH, where R.sub.7 is alkylene of 1 to about 7 carbon atoms, and NR.sub.8 R.sub.9 where R.sub.8 and R.sub.9 are independently hydrogen, alkyl, cycloaliphatic, heteroalicyclic or together form an alicyclic or heteroalicyclic radical in which the ring is completed through the nitrogen; with the proviso that when a is 1, Y is not OR.sub.6.Type: GrantFiled: March 18, 1986Date of Patent: July 19, 1988Assignee: The Lubrizol CorporationInventor: Betsy J. Butke
-
Patent number: 4749804Abstract: Pharmaceutically useful optically active .alpha.-arylalkanoic acids or esters, ortho esters, or amides thereof are stereoselectively prepared by contacting an aryl magnesium Grignard reagent with an optically active .alpha.-substituted acyl halide to form the optically active aryl .alpha.-substituted alkyl ketone, which is ketalized and rearranged to the desired optically active .alpha.-arylalkanoic acid or the corresponding ester, ortho ester or amide. In an alternate embodiment, the aryl .alpha.-substituted alkyl ketone is reduced to the corresponding alkanol, which is rearranged to the .alpha.-arylalkanal. The alkanal so produced is converted to the desired optically active .alpha.-arylalkanoic acid by conventional methods.Type: GrantFiled: June 10, 1986Date of Patent: June 7, 1988Assignee: Syntex (U.S.A.) Inc.Inventor: George C. Schloemer
-
Patent number: 4736055Abstract: Oxime sulfonates of formula I ##STR1## wherein Y is a polymerizable unsaturated group or epoxide group or an --OH, --NHR.sup.5, --COOH, COOR.sup.6, --COCl, --CH.sub.2 Hal, --SO.sub.2 Cl or --NCO group, Z is an (x+y)-valent connecting member, R.sup.1 and R.sup.2 are monovalent organic radicals, m is 0 or 1, x is 1 or 2 and y is 1 or 2, can be converted into polymers which can be thermally or photochemically dissociated to form free sulfonic acid groups. Said polymers can therefore be used as photoresists which can be developed with aqueous alkalis.Type: GrantFiled: April 11, 1986Date of Patent: April 5, 1988Assignee: Ciba-Geigy CorporationInventors: Kurt Dietliker, Werner Rutsch, Godwin Berner, Max Hunziker, Christopher G. Demmer
-
Patent number: 4727199Abstract: Active-hydrogen compounds, for example, primary and secondary alcohols or diols, are alkoxylated, for example, ethoxylated, using solid anion-bound metal oxide catalysts, such as, zirconium oxysulfate catalyst. Hydrous zicronium oxide is treated with solutions of sulfate phosphate, nitrate or tetrafluoroborate and calcined in air at 300.degree. to 950.degree. C. to produce highly active heterogeneous alkoxylation catalysts. The amorphous catalysts afford narrow molecular weight products. The catalyst can be removed from the product by filtration and reused with no significant loss in activity. Reaction temperatures of 50.degree. to 140.degree. C. are employed for alkoxylation.Type: GrantFiled: July 10, 1985Date of Patent: February 23, 1988Assignee: Union Carbide CorporationInventor: Stephen W. King
-
Patent number: 4727174Abstract: Compounds of the formula: ##STR1## wherein R is methyl or other lower alkyl group; X and X' individually are hydrogen, lower alkyl, aryl, or halogen; and R' is a 2-haloethyl group or other halogenated lower alkyl group are useful in the treatment of neoplastic diseases.Type: GrantFiled: April 4, 1986Date of Patent: February 23, 1988Assignee: Southern Research InstituteInventors: Y. Fulmer Shealy, Charles A. Krauth
-
Patent number: 4659855Abstract: Certain novel aryl sulfonyl fluorides, their preparation, and their use in inhibiting serine proteases with chymotrypsin-like and elastase-like specificity.Type: GrantFiled: May 9, 1983Date of Patent: April 21, 1987Assignee: Georgia Tech Research CorporationInventor: James C. Powers
-
Patent number: 4645852Abstract: In an improved process of converting a 1,2-epoxy-2-phenylbutane or a 1,2-epoxy-2-phenylpentane to a 2-hydroxy-2-phenylbutylsulfonate, sulfamate, or halide, or the corresponding 2-hydroxy-2-phenylpentyl compound, respectively, by the reaction at about 40.degree. to 120.degree. C. in the presence of an organic solvent of the requisite epoxybutane or epoxypentane with a proton source and a nucleophile. The proton source can be a free strong acid such as a sulfonic, sulfamic acid, or hydrohalide acid, or the proton source can be derived from an equilibrium system comprising a free strong acid and weak base in equilibrium with the respective deprotonated strong acid and protonated weak base. The process is carried out in one step with reduction or avoidance of aldehyde formation by rearrangement of the epoxyalkane.Type: GrantFiled: September 16, 1985Date of Patent: February 24, 1987Assignee: The Dow Chemical CompanyInventors: Lennon H. McKendry, Richard C. Krauss
-
Patent number: 4628120Abstract: A preparing method of optically active ketones given by a general formula ##STR1## (wherein R represents a hydrocarbon group having 2 to 20 carbon atoms and R' represents a hydrocarbon group having 1 to 20 carbon atoms. The hydrocarbon groups of R and R' may contain functional groups having no influence on the reaction. But, * represents an asymmetric carbon atom, and R represents a more electron donating group than R' (except when R=R') through the rearrangement reaction by using organoaluminum compound.Type: GrantFiled: October 16, 1984Date of Patent: December 9, 1986Assignee: Toyo Stauffer Chemical Co., Ltd.Inventors: Genichi Tsuchihashi, Keisuke Suzuki
-
Patent number: 4611074Abstract: Compounds of the formula: ##STR1## wherein R is methyl or other lower alkyl group; X and X' individually are hydrogen or lower alkyl; and R' is a 2-haloethyl group or other halogenated lower alkyl group are useful in the treatment of neoplastic diseases.Type: GrantFiled: November 19, 1984Date of Patent: September 9, 1986Assignee: Southern Research InstituteInventors: Y. Fulmer Shealy, Charles A. Krauth
-
Patent number: 4605758Abstract: Pharmaceutically useful optically active .alpha.-arylalkanoic acids or esters, ortho esters, or amides thereof are stereoselectively prepared by contacting an aryl magnesium Grignard reagent with an optically active .alpha.-substituted acyl halide to form the optically active aryl .alpha.-substituted alkyl ketone, which is ketalized and rearranged to the desired optically active .alpha.-arylalkanoic acid or the corresponding ester, ortho ester or amide. In an alternate embodiment, the aryl .alpha.-substituted alkyl ketone is reduced to the corresponding alkanol, which is rearranged to the .alpha.-arylalkanal. The alkanal so produced is converted to the desired optically active .alpha.-arylalkanoic acid by conventional methods.Type: GrantFiled: April 23, 1984Date of Patent: August 12, 1986Assignee: Syntex Pharmaceuticals International Ltd.Inventor: George C. Schloemer
-
Patent number: 4582905Abstract: Convenient intermediates for preparing 3-substituted-2-hydroxypropyl aryl ether .beta.-blockers, a reaction to the intermediates of the following formula and a conversion to obtain the said .beta.-blockers are disclosed. ##STR1## (wherein X is hydrogen or halogen; Y is halogen, hydroxy, lower acyloxy, amino, lower alkylamino, lower aralkylamino, lower acylamino, di-lower alkylamino, lower alkyleneamino, N-lower alkyl-N-lower aralkylamino, di-lower acylamino, N-lower alkyl-N-lower acylamino or N-tri-lower alkylsilylamino;one of P and R combined together with Q represents lower alkylene or alkenylene optionally interrupted by O, N or S and optionally substituted by lower alkyl, lower aralkyl, lower carboxylic acyl, carboxy, protected carboxy; hydroxy, lower alkoxy, lower acyloxy, oxo; amino, lower alkylamino, lower acylamino, nitro, nitroso, lower alkylthio, lower sulfonic acyl or halogen;and the remaining R or P is hydrogen or halogen;and dotted line represents the presence of one or two double bonds).Type: GrantFiled: December 20, 1984Date of Patent: April 15, 1986Assignee: Shionogi & Co., Ltd.Inventor: Makiko Sakai