Addition Salts Having Organic Nitrogen Containing Cation Patents (Class 562/114)
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Patent number: 9212263Abstract: A reactive ionic liquid to be used as an ionic component that is contained in an ion-containing layer in a transducer arranged in contact with a high-resistance layer as a dielectric layer of the transducer, and is restrained from migrating from the ion-containing layer to the high-resistance layer on application of a voltage is provided. The reactive ionic liquid comprises an ion pair that consists of an anion and a cation. In the reactive ionic liquid, (a) the anion comprises (a1) a reactive group that consists of an alkoxysilyl group and (a2) an anionic group consisting of a carboxylate (—COO?) group or a sulfonate (—SO3?) group. (b) The cation (b1) consists of an imidazolium, ammonium, pyrrolidinium, morpholinium, or phosphonium cation, and (b2) does not comprise an N—H group or a P—H group.Type: GrantFiled: June 16, 2014Date of Patent: December 15, 2015Assignees: SUMITOMO RIKO COMPANY LIMITED, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Shigeaki Takamatsu, Ryosuke Matsuno, Shingi Kumagai, Yota Kokubo, Kazunobu Hashimoto, Hitoshi Yoshikawa, Atsushi Takahara, Hideyuki Otsuka
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Publication number: 20150080601Abstract: The present invention is directed to an isomerized alpha olefin sulfonate and a method of making the same wherein the isomerized alpha olefin sulfonate is derived from sulfonating an isomerized alpha olefin with sulfur trioxide in the presence of air thereby producing an isomerized alpha olefin sulfonic acid, wherein the isomerized alpha olefin is derived from the isomerization of C12-C20 normal alpha olefins: and neutralizing the isomerized alpha olefin sulfonic acid with a source of an alkali metal or ammonium or substituted ammonium ion.Type: ApplicationFiled: November 19, 2014Publication date: March 19, 2015Inventors: Curtis B. Campbell, Andrew J. Howes
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Publication number: 20140243247Abstract: A composition of an oil-soluble ionic detergent that does not contribute metal ions to the composition, and which comprises a quaternary non-metallic pnictogen cation and an organic anion having at least one hydrocarbyl group of sufficient length to impart oil solubility to the detergent, the detergent having a total base number (TBN) to total acid number (TAN) ratio of at least 2:1 imparts ash-free basicity to a lubricant composition.Type: ApplicationFiled: May 14, 2014Publication date: August 28, 2014Applicant: The Lubrizol CorporationInventors: Ewan E. Delbridge, Virginia A. Carrick, John K. Pudelski, Matthew D. Giesleman, Christopher L. Friend, Patrick E. Mosier, Michele M. Rogers, Mark T. Tierney
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Publication number: 20140238900Abstract: The present invention is related to formulations consisting by block copolymers ?,?-di-aryl or alkyl sulfonates of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w of bis-ammonium and block copolymers ?,?-di-amine of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w, that are effective in the dewatering and desalting crude whose specific gravities are within the range of 14 to 23° API.Type: ApplicationFiled: February 25, 2014Publication date: August 28, 2014Inventors: Eugenio Alejandro FLORES OROPEZA, Cesar Andres FLORES SANDOVAL, Reyna REYES MARTINEZ, Jose Gonzalo HERNANDEZ CORTEZ, Alfonso LOPEZ ORTEGA, Laura Veronica CASTRO SOTELO, Fernando ALVAREZ RAMIREZ, Arquimedes ESTRADA MARTINEZ, Flavio Salvador VAZQUEZ MORENO
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Patent number: 8614346Abstract: The invention provides methods and compositions for preparing amphetamine conjugates, such as lisdexamfetamine, homoarginine-D-amphetamine, and salts thereof. In one embodiment, the invention provides methods of preparing an amphetamine conjugate from a chloramphetamine intermediate.Type: GrantFiled: June 18, 2010Date of Patent: December 24, 2013Assignee: Cambrex Charles City, Inc.Inventors: Paul Alan Jass, Todd Jeffrey Johnson, Jason Scott Douglas, Matthew Wendell Schiesher
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Publication number: 20130289112Abstract: Salts of kukoamine B, their preparation method and their pharmaceutical use in preparation of drugs for preventing and treating sepsis. Experiments indicate that salts of kukoamine B have a good effect on antagonizing the key factors inducing sepsis, and can be used in the preparation of drugs for preventing and treating sepsis. Under the current circumstances of the lack of effective measures for the treatment of sepsis in clinical practice, the medicinal formulations, which comprise the salts of kukoamine B, pharmaceutically acceptable carrier and/or diluent, provide a new approach for the prevention and treatment of sepsis.Type: ApplicationFiled: March 21, 2011Publication date: October 31, 2013Applicant: TIANJIN CHASESUN PHARMACEUTICAL CO., LTDInventors: Jiang Zheng, Xinchuan Zheng, Xin Liu, Hong Zhou, Ning Wang, Hongwei Cao, Yan Li, Yongling Lu, Kecen Zhao, Jingcheng Yang, Yang Yang, Yuanfeng Zhu, Guo Wei, Min Huang
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Patent number: 8546609Abstract: Problem: Providing a novel ionic liquid, which is low-cost, environment-friendly, and has low viscosity and melting point. Means for Solving the Problem: The present invention is the invention of the ionic liquid represented by the general formula [1]: {wherein, R1 to R3 and n pieces of R4 each independently represent hydrogen atom or alkyl group having 1 to 4 carbon atoms, R5 to R7 each independently represent alkyl group, aralkyl group, or aryl group, R8 represents alkyl group, aralkyl group, aryl group, or the one represented by the general formula [2]: (wherein T represents alkylene chain having 1 to 8 carbon atoms, n represents 1 or 2, and R1 to R7 are the same as the above-described), X represents nitrogen atom or phosphorus atom, n represents 1 or 2. When n is 1, R3 and R4 are bound and may form cyclohexene ring together with the adjacent carbon atoms. In addition, when X is nitrogen atom, R5 to R7 or R5 to R6 may form hetero ring with nitrogen atom binding thereto}.Type: GrantFiled: August 30, 2010Date of Patent: October 1, 2013Assignee: Wako Pure Chemical Industries, Ltd.Inventors: Tsutomu Watahiki, Kuniaki Okamoto, Motoshige Sumino
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Publication number: 20130137772Abstract: A salt of a polyamine having the formula: with a pharmaceutically acceptable organic or inorganic acid, wherein at least one of the bridging groups ALK1, ALK2 and ALK3 contains at least one —CH(OH)-group which is not alpha- to any of the nitrogen atoms.Type: ApplicationFiled: November 29, 2011Publication date: May 30, 2013Inventor: Raymond J. Bergeron
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Publication number: 20130039983Abstract: The invention relates to a new process for the production and/or purification of the salt of the compound (S)-2-[4-(2-fluorobenzyloxy)benzylamino]propanamide, i.e. ralfinamide, or the respective R-enantiomer, with methanesulfonic acid in high yields and very high enantiomeric and chemical purity in the form of the crystalline anhydrous polymorph identified as form A, wherein said salt is substantially free from impurities having genotoxic effect, such as (C1-C5)alkanylmethanesulfonates, and residual solvents known as potential precursors thereof, such as (C1-C5)alkanols or esters thereof with lower alkanoic acids.Type: ApplicationFiled: April 6, 2011Publication date: February 14, 2013Applicant: NEWRON PHARMACEUTICALS S.P.A.Inventors: Claudio Giordano, Erwin Waldvogel
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Publication number: 20120316350Abstract: A process for the preparation of N-monosubstituted ?-aminoalcohol sulfonates of formula (1a), (1b): wherein R1 is C6-20-aryl or C4-12-heteroaryl, each optionally being substituted with one or more halogen atoms and/or one or more C1-4-alkyl or C1-4-alkoxy groups, R2 is C1-4-alkyl or C6-20-aryl, each aryl optionally being substituted with one or more halogen atoms and/or one or more C1-4-alkyl or C1-4-alkoxy groups, and wherein R3 is selected from the group consisting of C1-18-alkyl, C6-20-cycloalkyl, C6-20-aryl and C7-20-aralkyl residues; including a) reacting a methyl ketone, a primary amine, formaldehyde and a sulfonic acid, at a pressure above 1.5 bar, optionally in a organic solvent, said organic solvent which can include water to provide N-monosubstituted ?-aminoketone sulfonates of formula (II): wherein R1, R2 and R3 are as defined above, and b) asymmetrically hydrogenating.Type: ApplicationFiled: July 27, 2012Publication date: December 13, 2012Applicant: Lonza AGInventors: Walter Brieden, Martin Clausen, John McGarrity, Hanspeter Mettler, Dominique Michel
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Patent number: 8283491Abstract: The present invention is directed to an isomerized alpha olefin sulfonate and a method of making the same wherein the isomerized alpha olefin sulfonate is derived from sulfonating an isomerized alpha olefin with sulfur trioxide in the presence of air thereby producing an isomerized alpha olefin sulfonic acid, wherein the isomerized alpha olefin is derived from the isomerization of C12-C40 normal alpha olefins; and neutralizing the isomerized alpha olefin sulfonic acid with a source of a mono-valent cation.Type: GrantFiled: October 23, 2008Date of Patent: October 9, 2012Assignee: Chevron Oronite Company LLCInventors: Curtis Bay Campbell, Theresa Ann Denslow
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Publication number: 20120226030Abstract: Rinsable dyes with improved fugitivity are formulated by attaching dyestuff compounds with amine-capped sulfonic solubilizing groups to commercially available ethoxylated aniline, so that the surfactant effect of the ethoxylated aniline counteracts the substantivity of the dyestuff compound, while the neutralization of the sulfonic solubilizing groups reduces substantivity.Type: ApplicationFiled: May 16, 2012Publication date: September 6, 2012Inventors: Mark Berenfeld, Sai Harfouch, Peter Caputo
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Patent number: 8258338Abstract: A process for the preparation of N-monosubstituted ?-aminoalcohol sulfonates of formula (Ia), (Ib): wherein R1 is C6-20-aryl or C4-12-heteroaryl, each optionally being substituted with one or more halogen atoms and/or one or more C1-4-alkyl or C1-4-alkoxy groups, R2 is C1-4-alkyl or C6-20-aryl, each aryl optionally being substituted with one or more halogen atoms and/or one or more C1-4-alkyl or C1-4-alkoxy groups and wherein R3 is selected from the group consisting of C1-18-alkyl, C6-20-cycloalkyl, C6-20-aryl and C7-20-aralkyl residues. The process has the steps of (a) reacting a methyl ketone, a primary amine, formaldehyde and a sulfonic acid, at a pressure above 1.5 bar, optionally in a organic solvent, the organic solvent optionally containing water, to afford N-monosubstituted ?-aminoketone sulfonates of formula (II): wherein R1, R2 and R3 are as defined above, and (b) asymmetrically hydrogenating.Type: GrantFiled: February 14, 2006Date of Patent: September 4, 2012Assignee: Lonza AGInventors: Walter Brieden, Martin Clausen, John McGarrity, Hanspeter Mettler, Colette Mettler, legal representative, Dominique Michel
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Publication number: 20120190880Abstract: The invention provides methods and compositions for preparing amphetamine conjugates, such as lisdexamfetamine, homoarginine-D-amphetamine, and salts thereof. In one embodiment, the invention provides methods of preparing an amphetamine conjugate from a chloramphetamine intermediate.Type: ApplicationFiled: June 18, 2010Publication date: July 26, 2012Inventors: Paul Alan Jass, Todd Jeffrey Johnson, Jason Scott Douglas, Matthew Wendell Schiesher
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Publication number: 20120157680Abstract: PROBLEM: Providing a novel ionic liquid, which is low-cost, environment-friendly, and has low viscosity and melting point. MEANS FOR SOLVING THE PROBLEM: The present invention is the invention of the ionic liquid represented by the general formula [1]: {wherein, R1 to R3 and n pieces of R4 each independently represent hydrogen atom or alkyl group having 1 to 4 carbon atoms, R5 to R7 each independently represent alkyl group, aralkyl group, or aryl group, R8 represents alkyl group, aralkyl group, aryl group, or the one represented by the general formula [2]: (wherein T represents alkylene chain having 1 to 8 carbon atoms, n represents 1 or 2, and R1 to R7 are the same as the above-described), X represents nitrogen atom or phosphorus atom, n represents 1 or 2. When n is 1, R3 and R4 are bound and may form cyclohexene ring together with the adjacent carbon atoms. In addition, when X is nitrogen atom, R5 to R7 or R5 to R6 may form hetero ring with nitrogen atom binding thereto}.Type: ApplicationFiled: August 30, 2010Publication date: June 21, 2012Applicant: Wako Pure Chemical Industries, Ltd.Inventors: Tsutomu Watahiki, Kuniaki Okamoto, Motoshige Sumino
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Patent number: 8173353Abstract: The present invention provides a sulfonium compound represented by the formula (I): wherein Q1 and Q2 each independently represent a fluorine atom or a C1-C6 perfluoroalkyl group, R1 represents a C5-C42 organic group having a ?-ketoester structure and A+ represents an organic counter ion, and a chemically amplified photoresist composition comprising the above-mentioned sulfonium compound and a resin comprising a structural unit having an acid-labile group and being insoluble or poorly soluble in an aqueous alkali solution but becoming soluble in an aqueous alkali solution by the action of an acid.Type: GrantFiled: March 23, 2010Date of Patent: May 8, 2012Assignee: Sumitomo Chemical Company, LimitedInventors: Tatsuro Masuyama, Junji Shigematsu, Hanwoo Park
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Publication number: 20120101168Abstract: The subject invention provides deuterated rasagiline, its salts and uses.Type: ApplicationFiled: October 25, 2011Publication date: April 26, 2012Inventors: Eliezer Bahar, Anton Frenkel, Victor Piryatinsky
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Publication number: 20120100184Abstract: Process for manufacturing 1-amino-1,3,3,5,5-pentamethylcyclohexane mesylate comprising step (i): (i) reacting 1-amino-1,3,3,5,5-pentamethylcyclohexane with methane sulfonic acid in a solvent or a mixture of two or more solvents selected from anisole, cumene, pentane, hexane, heptane, isooctane, methyl acetate, propyl acetate, isopropyl acetate, n-butyl acetate, isobutyl acetate, methyl ethyl ketone, methyl isopropylketone, methyl isobutyl ketone, dimethyl sulphoxide, tetrahydrofuran, methyltetrahydrofuran, 1,1-diethoxypropane, 1,1-dimethoxymethane, and 2,2-dimethoxypropane.Type: ApplicationFiled: April 16, 2010Publication date: April 26, 2012Applicant: MERZ PHARMA GmbH & CO.KGaAInventors: Markus Henrich, Simona Negura, Gergely Tasi, Pal Kocsan, Federico Sbrogio, Michael Pyerin, Herbert Koller
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Patent number: 8134024Abstract: Disclosed is a new ionic liquid monomer salt and methods of is synthesis and polymerization. The ionic liquid monomer salt is prepared by mixing equimolar amounts of an amine, such as tris[2-(2-methoxyethoxy)-ethyl]amine and an acid functionalized polymerizable monomer, such as 2-acrylamido-2-methyl-1-propanesulfonic acid, which is stirred at ambient temperature until salt formation is complete. Also disclosed is a new ionic liquid polymer salts and method for making the same. The synthesis of 2-acrylamido-2-methyl-1-propanesulfonic acid-ammonium salt polymer is accomplished by adding 2,2?-azobisisobutyronitrile (AIBN) to the ionic liquid monomer salt and heating the homogeneous melt at 70° C. for 18 hr.Type: GrantFiled: October 5, 2010Date of Patent: March 13, 2012Assignee: The United States of America as represented by the Secretary of the NavyInventors: Holly L Ricks-Laskoski, Arthur W Snow
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Publication number: 20110152537Abstract: The present invention relates to chemical compounds comprising a [Y(CHRa)n—CH(Ra)SO3]? anion, their preparation and application. The chemical compounds are preferably ionic liquids.Type: ApplicationFiled: May 12, 2009Publication date: June 23, 2011Applicant: MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNGInventors: Peter Wasserscheid, Natalia Paape, Andreas Boesmann, Peter Schulz
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Publication number: 20110112200Abstract: The present invention provides crystalline and amorphous salts of O-desmethylvenlafaxine and processes for preparing said salts of O-desmethylvenlafaxine. The present invention further provides pharmaceutical compositions comprising said salts of O-desmethylvenlafaxine.Type: ApplicationFiled: June 16, 2009Publication date: May 12, 2011Inventors: Valerie Niddam-Hildesheim, Tamar Nidam, Eli Lancry
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Publication number: 20110105788Abstract: The invention relates to a polymorphic form of rasagiline mesylate, and to processes for preparing the same.Type: ApplicationFiled: March 27, 2009Publication date: May 5, 2011Applicant: MEDICHEM, S.A.Inventors: Stephen Benedict David Winter, Maria Carmen Burgarolas Montero
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Patent number: 7858822Abstract: Disclosed is a new ionic liquid monomer salt and methods of is synthesis and polymerization. The ionic liquid monomer salt is prepared by mixing equimolar amounts of an amine, such as tris[2-(2-methoxyethoxy)-ethyl]amine and an acid functionalized polymerizable monomer, such as 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), which is stirred at ambient temperature until salt formation is complete. Also disclosed is a new ionic liquid polymer salts and method for making the same. The synthesis of AMPS-ammonium salt polymer is accomplished by adding 2,2?-azobisisobutyronitrile (AIBN) to the ionic liquid monomer salt and heating the homogeneous melt at 70° C. for 18 hr.Type: GrantFiled: August 24, 2010Date of Patent: December 28, 2010Assignee: The United States of America as represented by the Secretary of the NavyInventors: Holly L. Ricks-Laskoski, Arthur W Snow
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Patent number: 7807852Abstract: Disclosed is a new ionic liquid monomer salt and methods of is synthesis and polymerization. The ionic liquid monomer salt is prepared by mixing equimolar amounts of an amine, such as tris[2-(2-methoxyethoxy)-ethyl]amine and an acid functionalized polymerizable monomer, such as 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), which is stirred at ambient temperature until salt formation is complete. Also disclosed is a new ionic liquid polymer salts and method for making the same. The synthesis of AMPS-ammonium salt polymer is accomplished by adding 2,2?-azobisisobutyronitrile (AIBN) to the ionic liquid monomer salt and heating the homogeneous melt at 70° C. for 18 hr.Type: GrantFiled: August 17, 2007Date of Patent: October 5, 2010Assignee: The United States of America as represented by the Secretary of the NavyInventors: Holly L. Ricks-Laskoski, Arthur W. Snow
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Patent number: 7713679Abstract: There is provided a compound represented by a general formula (B1-1) shown below, an acid generator composed of the above compound, a resist composition containing an acid generator composed of the above compound, and a method of forming a resist pattern: (wherein RX represents a hydrocarbon group which may contain a substituent group; Q1 represents an alkylene group of 1 to 12 carbon atoms which may contain a substituent group, or a single bond; n represents an integer of 0 or 1; Y1 represents an alkylene group of 1 to 4 carbon atoms, or a fluorinated alkylene group of 1 to 4 carbon atoms; and A+ represents an organic cation which contains a nitrogen atom).Type: GrantFiled: October 14, 2008Date of Patent: May 11, 2010Inventors: Keita Ishiduka, Yoshiyuki Utsumi, Akiya Kawaue, Takehiro Seshimo, Hideo Hada
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Publication number: 20090176963Abstract: Provided is a new organic-acid-based catalyst enabling production of a polyhydroxycarboxylic acid by direct dehydration polycondensation of a hydroxycarboxylic acid such as L-lactic acid, specifically, an organic-acid-based catalyst comprising an amine salt of a sulfonic acid or a phosphine salt of a sulfonic acid for production of polyhydroxycarboxylic acids such as poly-L-lactic acid.Type: ApplicationFiled: June 12, 2007Publication date: July 9, 2009Inventors: Atsushi Abiko, Hisako Iwahashi
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Patent number: 7534906Abstract: The invention concerns a method for synthesis of hydrogenofluoromethylenesulphonyl radical derivatives, comprising: a) a step which consists in condensing a thiolate (that is a monoalkyl sulphide salt) with a compound having a sp; 3hybridized carbon bearing a hydrogen, a fluorine, a heavy halogen selected among chlorine, bromine and iodine and an electron-attracting group selected among fluorine and those whereof the; is not less than 0.2, advantageously than 0.4; b) a step which consists in oxidizing the compound obtained in step a). The invention is applicable to the synthesis of various compounds having a suphinyl or sulphonyl group.Type: GrantFiled: June 24, 2003Date of Patent: May 19, 2009Assignee: Rhodia ChimieInventor: Laurent Saint-Jalmes
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Patent number: 7189798Abstract: This invention relates to new cyclodextrin derivatives, processes for producing these cyclodextrin derivatives, and inclusion complexes comprised of the new cyclodextrin derivatives and guest molecules, as well as methods of making such materials and related materials and methods of using the same.Type: GrantFiled: June 24, 2003Date of Patent: March 13, 2007Assignee: Eastman Chemical CompanyInventors: Charles M. Buchanan, Steven N. Falling, Juanelle L. Lambert, Shannon E. Large, Jozsef Szejtli, Lajos Szente, Laszlo Jicsinszky
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Patent number: 7060851Abstract: Chiral hydroxyethylamine, hydroxyethylurea or hydroxyethylsulfonamide isostere containing retroviral protease and renin inhibitors can be prepared by multi-step syntheses that utilize key chiral amine intermediates. This invention is a cost effective method of obtaining such key chiral amine intermediates enantiomerically, diastereomerically and chemically pure. The method is suitable for large scale (multikilogram) productions. This invention also encompasses organic acid and inorganic acid salts of the amine intermediates.Type: GrantFiled: October 12, 2004Date of Patent: June 13, 2006Assignee: G.D. Searle & Co.Inventors: John S Ng, Claire A Przybyla, Shu-Hong Zhang
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Patent number: 6900245Abstract: The present invention relates to a pharmaceutical composition for treating or preventing obesity, comprising novel crystalline sibutramine methanesulfonate hemihydrate of formula (I).Type: GrantFiled: October 3, 2003Date of Patent: May 31, 2005Assignee: Hanmi Pharm. Co., Ltd.Inventors: Jae-Heon Lee, Gha-Seung Park, Jae-Cheol Lee, Han-Kyong Kim, Young-Kil Chang, Gwan-Sun Lee
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Patent number: 6858414Abstract: The present invention provides a purification process whereby deferoxamine B produced by a microorganism and in mixture with other polyhydroxamates produced by the microorganism may be converted into its mesylate salt substantially free of the other polyhydroxamates and substantially free of chloride ion. The process includes adsorption and desorption of the deferoxamine B on an adsorption resin, direct precipitation of the deferoxamine free base out of the eluent from the adsorption resin, contacting of the deferoxamine B free base with methanesulfonic acid and isolation of the deferoxamine B mesylate salt by precipitation. This process minimizes decomposition of deferoxamine B.Type: GrantFiled: November 30, 2000Date of Patent: February 22, 2005Assignee: Biogal Gyógyszergyár Rt.Inventors: Vilmos Keri, Zoltan Czovek, Attila Mezo
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Patent number: 6849760Abstract: Chiral hydroxyethylamine, hydroxyethylurea or hydroxyethylsulfonamide isostere containing retroviral protease and renin inhibitors can be prepared by multi-step syntheses that utilize key chiral amine intermediates. This invention is a cost effective method of obtaining such key chiral amine intermediates enantiomerically, diastereomerically and chemically pure. The method is suitable for large scale (multikilogram) productions. This invention also encompasses organic acid and inorganic acid salts of the amine intermediates.Type: GrantFiled: December 23, 2002Date of Patent: February 1, 2005Assignee: G. D. Searle & Co.Inventors: John S Ng, Claire S Przybyla, Shu-Hong Zhang
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Patent number: 6765112Abstract: A process that can be used for manufacturing a tetraalkylonium perfluoroalkylsulfonate is provided. The process comprises contacting a tetraalkylonium halide with a metal perfluoroalkyl sulfonate to produce a mixture; allowing the second mixture to produce an aqueous upper layer and a separate lower liquid layer; separating the lower liquid layer from the upper aqueous layers to produce a product layer; optionally washing the product layer with 1 to 10 volumes of water, based on the volume of the product layer at a temperature of about 50° C. to about 100° C. to produce a washed product layer; and drying the product layer or washed product.Type: GrantFiled: March 25, 2003Date of Patent: July 20, 2004Assignee: E. I. du Pont de Nemours and CompanyInventor: James A. Schultz
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Publication number: 20030198607Abstract: Compounds of Formula I 1Type: ApplicationFiled: April 10, 2002Publication date: October 23, 2003Applicant: EM IndustriesInventor: Ratan K. Chaudhuri
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Patent number: 6521785Abstract: The present invention relates to surfactants useful in life science and industrial formulations. More particularly, the invention relates to surfactants of alkoxylated amine neutralized by aromatic sulfonic acid and pesticide formulations containing the same.Type: GrantFiled: February 5, 2001Date of Patent: February 18, 2003Assignee: Syngenta Participations AGInventors: Tammy Tyler Shannon, Carolyn Estep Moore, Victor Shui-Chiu Chow
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Patent number: 6506804Abstract: Disclosed are ethylenically unsaturated amine salts of sulfonic, phosphoric and carboxylic acids. The salts are surface active agents which are useful in a variety of applications as primary and/or secondary surfactants. The salts are especially useful as surfactants in emulsion polymerization reactions.Type: GrantFiled: March 8, 2001Date of Patent: January 14, 2003Assignee: Stepan CompanyInventor: Alfred K. Schultz
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Patent number: 6388126Abstract: The invention features the use of flourosulphonates to release the organic bases from their fluorohydrate. This use is characterised in that a hydrogenofluorosulphonate of an organic base is formed and in that the hydrofuoric acid which is associated with the said base or with one of its precursors is separated therefrom. The invention is useful in organic synthesis applications.Type: GrantFiled: January 25, 2001Date of Patent: May 14, 2002Assignee: Rhodia ChimieInventors: Laurent Saint-Jalmes, Marcel Morel
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Patent number: 5866040Abstract: A novel complex containing an ampholytic and/or semi-polar surfactant as well as a higher fatty acid, and if necessary, a clay mineral, and an emulsified composition containing this complex.Type: GrantFiled: July 27, 1994Date of Patent: February 2, 1999Assignee: Shiseido Company, Ltd.Inventors: Yasunari Nakama, Michihiro Yamaguchi, Kiyoshi Miyazawa, Takayuki Ohmura
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Patent number: 5814110Abstract: Distillate fuel is treated with additives whose structure match the crystal planes of the wax which crystallizes from the fuel to produce crystals below 4000 nanometres in size, suitable additive include novel sulpho-carboxylic materials particularly their esters and amine derivatives such as the amine salts and/or amides of ortho-sulpho benzoic acid.Type: GrantFiled: November 23, 1994Date of Patent: September 29, 1998Assignee: Exxon Chemical Patents Inc.Inventors: Kenneth William Bartz, Jacqueline Dawn Bland, David Paul Gillingham, Richard Dix Kerwood, Edwin William Lehmann, Kenneth Lewtas, John Edward Maddox, Albert Rossi, Robert Dryden Tack
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Patent number: 5411933Abstract: Antimicrobial compounds of the formula ##STR1## wherein R, R.sup.1 and R.sup.2 are selected according to the following:A. R is (C.sub.11 -C.sub.16) alkyl (straight or branched), and R.sup.1 and R.sup.2 are joined to form a morpholine, pyrrolidine, or piperidine ring with the N;B. R is (C.sub.11 -C.sub.16) and R.sup.1 and R.sup.2 are independently selected from (C.sub.1 -C.sub.3) alkyl which in the case of C.sub.3 can be branched; andC. R.sup.1 and R.sup.2 are the same and are (C.sub.6 -C.sub.12) alkyl, straight or branched, and R is (C.sub.1 -C.sub.16) alkyl, straight or branched; andX.sup.- =an anion preferably selected from chlorine, bromine, iodine, phosphate, acetate, benzoate, citrate, tartrate, alkyl- or aryl-sulfonate, and alkylsulfate.Type: GrantFiled: March 11, 1994Date of Patent: May 2, 1995Assignee: Rohm & Haas CompanyInventor: Adam C. Hsu
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Patent number: 5374771Abstract: A process for the preparation of high-purity deferoxamine salts from filtered fermentation liquors containing deferoxamine B as active ingredient by the adsorption of the active ingredient onto an ion exchange resin and the subsequent dissolution and purification thereof, which comprises carrying out the separation of the deferoxamine salt subsequent to the concentration of the eluate by salting out from an aqueous solution or from a mixture of water and an organic solvent and purifying it by repeated salting out and/or by methods known per se, and optionallya) preparing the methanesulfonate salt by known methods, orb) passing the aqueous solution of the deferoxamine salt trough an ion exchange resin containing methanesulfonate anions as counter ions and recovering the methanesulfonate salt from the effluent, preferably by lyophilization.Type: GrantFiled: May 27, 1993Date of Patent: December 20, 1994Assignee: Biogal Gyogyszergyar Rt.Inventors: Zoltan Konyari, Vilmos Keri, Antal Kovacs, Sandor Horkay, Laszlo Eszenyi, Janos Erdelyi, Ilona Himesi, Gyorgy Toth, Janos Balint, SzilaJudit, Ferenc Vinczi, Csaba Szabo, Nelli Sas
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Patent number: 5344949Abstract: Surface active anion-cation complexes are synthesized where an organic or organosilicon compound with at least one epoxide group is reacted with a quaternary ammonium hydrogen sulfite of the general formulaHN.sup.+ (R.sup.1).sub.3 SO.sub.3 H.sup.- IwhereinR.sup.1 within the molecule is the same or different and can be(1) an alkyl or hydroxyalkyl group with 1 to 18 carbon atoms,(2) a phenyl group, or(3) a group of the formula C.sub.n H.sub.2n+1 CONH--(CH.sub.2).sub.m --, in which n can be a number from 7 to 17 and m is 2 or 3,in the presence of a polar solvent in such amounts so that the molar ratio of the epoxide group to HN.sup.+ (R.sup.1).sub.3 SO.sub.3 H.sup.- is 2:1.Type: GrantFiled: July 14, 1993Date of Patent: September 6, 1994Assignee: Th. Goldschmidt AGInventors: Gotz Koerner, Klaus-Dieter Klein, Dietmar Schaefer
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Patent number: 5246965Abstract: The invention relates to the compounds of the formula ##STR1## wherein the C(.dbd.NH)--NHR group may be in tautomeric or isomeric form, and pharmaceutically acceptable salts thereof, in which:R is hydrogen or an acyl radical which is derived from an organic carbonic acid, an organic carboxylic acid, a sulfonic acid, or a carbamic acid;R.sub.1 is a substituent selected from an aliphatic hydrocarbon radical, an araliphatic hydrocarbon radical and a cycloaliphatic hydrocarbon radical;X.sub.1 and X.sub.3, independently of one another, are oxygen (--O--) or sulphur (--S--); andX.sub.Type: GrantFiled: September 17, 1992Date of Patent: September 21, 1993Assignee: Ciba-GeigyInventor: Alan J. Main
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Patent number: 5245075Abstract: Amino-derivative (poly)peroxycarboxylic acids which have the formula: ##STR1## wherein the symbols have the following meanings: R, R.sub.1, and R.sub.2, which may be equal to or different from one another, represent hydrogen atoms, alkyl groups or groups selected from R, R.sub.1 and R.sub.2, which taken together with the nitrogen atom to which they are linked, give rise to an aliphatic heterocyclic group, all of them being optionally substituted;A represents a (cyclo) alkylene group, an arylene group which may also be condensed with cycloaliphatic groups, a cycloalkylene-alkylene or an alkylene-cycloalkylene group, an arylene-alkylene or an alkylene-arylene group, which may be condensed with cyclo-aliphatic groups wherein said alkylene group may also be interrupted by --CONR.sub.3 groups, wherein R.sub.3 represents a hydrogen atom or an alkyl or aryl group;X.sup.- represents HSO.sub.4.sup.- or CH.sub.3 SO.sub.3.sup.- ; a process for their preparation; and their use as bleaching agents.Type: GrantFiled: December 9, 1991Date of Patent: September 14, 1993Assignee: Ausimont S.r.l.Inventors: Carlo Venturello, Claudio Cavallotti
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Patent number: 5166416Abstract: The invention relates to new propenone oxime ethers, a method of preparing them and pharmaceutical compositions containing them.Said new propenone oxime ethers have the formula ##STR1## in which--Ar and Ar' each independentlyl denotes a phenyl group non-substituted, mono or polysubstituted, a 9-anthryl group or a naphthyl group, a pyridyl, thienyl or furyl group;R.sub.1 R.sub.2 each independently denotes hydrogen, a C.sub.1 -C.sub.4 alkyl group or together with the N-atom to which they are bonded a 1-pyrrolidinyl, piperidino, morpholino or 1-piperazinyl group;M=H, Cl, Br or a C.sub.1 -C.sub.6 alkyl groupn=2 or 3.The invention also deals with the salts of compounds of formula (I). Said compounds have good activity in the anti platelet-clotting tests and are also antagonists of the 5HT.sub.2 receptors.Type: GrantFiled: December 1, 1989Date of Patent: November 24, 1992Assignee: Societe Anonyme: SanofiInventors: Christian Congy, Patrick Gueule, Bernard Labeeuw, Murielle Rinaldi
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Patent number: 5068405Abstract: Halogenated N-sulfamyl propionamidine addition salts corresponding to the formula ##STR1## are provided, in which X represents halogen and A represents an acid selected from sulfuric acid, nitric acid, benzenesulfonic acid; toluenesulfonic acid; 2,4,5-trichlorobenzenesulfonic acid; trichloroacetic acid; trifluoroacetic acid or methanesulfonic acid. They are useful as intermediates in the preparation of famotidine. They are prepared by reacting a halogenated propionitrile with the respective acid.Type: GrantFiled: July 6, 1990Date of Patent: November 26, 1991Assignee: Delmar Chemicals Inc.Inventors: Michel Bekhazi, Josef Oren
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Patent number: 5053531Abstract: Described are certain quaternary ammonium alkyl benzene sulfonate salts and certain quaternary ammonium alkane sulfonate salts, e.g., octyl dimethyl hydroxyethyl ammonium dodecyl benzene sulfonate and octyl dimethyl hydroxyethyl ammonium methane sulfonate which are useful as antistatic agents for synthetic polymer articles.Type: GrantFiled: December 12, 1989Date of Patent: October 1, 1991Assignee: PPG Industries, Inc.Inventor: Cheruthur Govindan
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Patent number: RE44032Abstract: Disclosed is a new ionic liquid monomer salt and methods of is synthesis and polymerization. The ionic liquid monomer salt is prepared by mixing equimolar amounts of an amine, such as tris[2-(2-methoxyethoxy)-ethyl]amine and an acid functionalized polymerizable monomer, such as 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), which is stirred at ambient temperature until salt formation is complete. Also disclosed is a new ionic liquid polymer salts and method for making the same. The synthesis of AMPS 2-acrylamido-2-methyl-1-propanesulfonic acid-ammonium salt polymer is accomplished by adding 2,2?-azobisisobutyronitrile (AIBN) to the ionic liquid monomer salt and heating the homogeneous melt at 70° C. for 18 hr.Type: GrantFiled: January 5, 2011Date of Patent: February 26, 2013Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Holly L. Ricks-Laskoski, Arthur W Snow
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Patent number: RE44988Abstract: Disclosed is a new ionic liquid monomer salt and methods of is synthesis and polymerization. The ionic liquid monomer salt is prepared by mixing equimolar amounts of an amine, such as tris[2-(2-methoxyethoxy)-ethyl]amine and an acid functionalized polymerizable monomer, such as 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), which is stirred at ambient temperature until salt formation is complete. Also disclosed is a new ionic liquid polymer salts and method for making the same. The synthesis of AMPS-ammonium salt polymer is accomplished by adding 2,2?-azobisisobutyronitrile (AIBN) to the ionic liquid monomer salt and heating the homogeneous melt at 70° C. for 18 hr.Type: GrantFiled: February 11, 2013Date of Patent: July 1, 2014Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Holly L. Ricks-Laskoski, Arthur W. Snow